Accession_ID	Pathway_Count	Pathway_IDs	Pathway_Names
Lalb_05471	3	MetaCyc: PWY-7887;Reactome: R-HSA-6787450;MetaCyc: PWY-7892	"Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)"
Lalb_12513	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_06570	20	Reactome: R-HSA-5656169;Reactome: R-HSA-5685938;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-110312;Reactome: R-HSA-5693616;Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-110314	"Termination of translesion DNA synthesis";"HDR through Single Strand Annealing (SSA)";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Translesion synthesis by REV1";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Recognition of DNA damage by PCNA-containing replication complex"
Lalb_01857	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_04262	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
Lalb_09269	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
Lalb_02739	4	Reactome: R-HSA-379716;KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
Lalb_05964	3	Reactome: R-HSA-5362798;Reactome: R-HSA-8957275;Reactome: R-HSA-381426	"Release of Hh-Np from the secreting cell";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
Lalb_08082	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
Lalb_11271	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
Lalb_06304	5	Reactome: R-HSA-3249367;Reactome: R-HSA-3134975;Reactome: R-HSA-6798695;Reactome: R-HSA-1834941;Reactome: R-HSA-3270619	"STAT6-mediated induction of chemokines";"Regulation of innate immune responses to cytosolic DNA";"Neutrophil degranulation";"STING mediated induction of host immune responses";"IRF3-mediated induction of type I IFN"
Lalb_12570	3	Reactome: R-HSA-373080;Reactome: R-HSA-4608870;Reactome: R-HSA-4086400	"Class B/2 (Secretin family receptors)";"Asymmetric localization of PCP proteins";"PCP/CE pathway"
Lalb_06910	34	Reactome: R-HSA-167152;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-5696395;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-6782135;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-6782210;Reactome: R-HSA-73762;Reactome: R-HSA-76042;Reactome: R-HSA-6807505;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-8939236;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-69273;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-73863;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-69231;Reactome: R-HSA-167246	"Formation of HIV elongation complex in the absence of HIV Tat";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"Dual incision in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Cyclin D associated events in G1";"Tat-mediated elongation of the HIV-1 transcript"
Lalb_09928	7	Reactome: R-HSA-381042;Reactome: R-HSA-3371453;Reactome: R-HSA-114608;Reactome: R-HSA-983170;Reactome: R-HSA-381033;Reactome: R-HSA-381183;Reactome: R-HSA-381070	"PERK regulates gene expression";"Regulation of HSF1-mediated heat shock response";"Platelet degranulation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperones";"ATF6 (ATF6-alpha) activates chaperone genes";"IRE1alpha activates chaperones"
Lalb_10277	6	Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756	"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation"
Lalb_06812	4	MetaCyc: PWY-7511;Reactome: R-HSA-8866427;Reactome: R-HSA-983168;Reactome: R-HSA-9031525	"Protein ubiquitination";"VLDLR internalisation and degradation";"Antigen processing: Ubiquitination & Proteasome degradation";"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake"
Lalb_02720	4	Reactome: R-HSA-72764;Reactome: R-HSA-6782315;Reactome: R-HSA-156581;Reactome: R-HSA-6790901	"Eukaryotic Translation Termination";"tRNA modification in the nucleus and cytosol";"Methylation";"rRNA modification in the nucleus and cytosol"
Lalb_00701	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis"
Lalb_06563	1	Reactome: R-HSA-1632852	"Macroautophagy"
Lalb_14741	1	Reactome: R-HSA-611105	"Respiratory electron transport"
Lalb_03243	5	MetaCyc: PWY-7269;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
Lalb_08602	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
Lalb_11619	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
Lalb_13956	5	MetaCyc: PWY-7922;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)"
Lalb_07211	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
Lalb_06361	57	Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-6798695;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-5610785;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-174113	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RAS by GAPs";"Degradation of AXIN";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neutrophil degranulation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"GLI3 is processed to GLI3R by the proteasome";"Interleukin-1 signaling";"Hedgehog 'on' state";"SCF-beta-TrCP mediated degradation of Emi1"
Lalb_14613	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
Lalb_08656	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
Lalb_14088	5	Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-9615710	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy"
Lalb_12076	7	KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00052+3.2.1.23	"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Other glycan degradation";"Sphingolipid metabolism";"Neutrophil degranulation";"Galactose metabolism"
Lalb_03353	2	Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2	"Glycine degradation";"Glycine, serine and threonine metabolism"
Lalb_05613	1	Reactome: R-HSA-8951664	"Neddylation"
Lalb_00185	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
Lalb_09757	10	Reactome: R-HSA-4719360;Reactome: R-HSA-4719377;MetaCyc: PWY-7921;KEGG: 00510+2.4.1.83;MetaCyc: PWY-7979;Reactome: R-HSA-162699;MetaCyc: PWY-7661;Reactome: R-HSA-913709;Reactome: R-HSA-4717374;MetaCyc: PWY-7922	"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Protein O-mannosylation I (yeast)";"N-Glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Synthesis of dolichyl-phosphate mannose";"Protein N-glycosylation (Haloferax volcanii)";"O-linked glycosylation of mucins";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Protein O-mannosylation II (mammals, core M1 and core M2)"
Lalb_05109	6	Reactome: R-HSA-3299685;Reactome: R-HSA-8862803;MetaCyc: PWY-6854;Reactome: R-HSA-8950505;Reactome: R-HSA-2151201;Reactome: R-HSA-9615017	"Detoxification of Reactive Oxygen Species";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Ethylene biosynthesis III (microbes)";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Transcriptional activation of mitochondrial biogenesis";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"
Lalb_14076	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
Lalb_01274	1	Reactome: R-HSA-1483191	"Synthesis of PC"
Lalb_04947	14	Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-203927;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-426486;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519	"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"MicroRNA (miRNA) biogenesis";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Small interfering RNA (siRNA) biogenesis";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression"
Lalb_09022	4	Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-400511	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
Lalb_07402	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
Lalb_07066	4	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
Lalb_06283	7	Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-6798695;Reactome: R-HSA-390471	"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation";"Association of TriC/CCT with target proteins during biosynthesis"
Lalb_05322	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
Lalb_03446	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
Lalb_03869	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
Lalb_10312	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
Lalb_09847	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
Lalb_08137	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
Lalb_14268	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_05036	4	Reactome: R-HSA-3371568;Reactome: R-HSA-3371497;Reactome: R-HSA-8939211;Reactome: R-HSA-9018519	"Attenuation phase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"ESR-mediated signaling";"Estrogen-dependent gene expression"
Lalb_03430	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
Lalb_07949	3	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841;Reactome: R-HSA-383280	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines";"Nuclear Receptor transcription pathway"
Lalb_07420	1	Reactome: R-HSA-8951664	"Neddylation"
Lalb_01153	14	KEGG: 00561+3.1.3.4;Reactome: R-HSA-75109;MetaCyc: PWY-8052;MetaCyc: PWY-8051;KEGG: 00600+3.1.3.4;Reactome: R-HSA-4419969;Reactome: R-HSA-1483191;MetaCyc: PWY-7782;Reactome: R-HSA-1483213;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053;KEGG: 00564+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8055	"Glycerolipid metabolism";"Triglyceride biosynthesis";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis I";"Sphingolipid metabolism";"Depolymerisation of the Nuclear Lamina";"Synthesis of PC";"Plasmalogen biosynthesis";"Synthesis of PE";"Ether lipid metabolism";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis"
Lalb_06536	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
Lalb_08188	5	KEGG: 04070+2.7.7.41;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-7817;MetaCyc: PWY-5667	"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis I"
Lalb_05031	12	Reactome: R-HSA-70263;KEGG: 00680+4.1.2.13;KEGG: 00051+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-1042;KEGG: 00010+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-6142;MetaCyc: PWY-1861;KEGG: 00030+4.1.2.13	"Gluconeogenesis";"Methane metabolism";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway"
Lalb_10525	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
Lalb_03767	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
Lalb_02853	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
Lalb_08549	4	MetaCyc: PWY-6030;Reactome: R-HSA-209931;KEGG: 00380+1.14.16.4;KEGG: 00790+1.14.16.4	"Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis";"Tryptophan metabolism";"Folate biosynthesis"
Lalb_03568	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
Lalb_00199	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
Lalb_06462	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
Lalb_03712	4	Reactome: R-HSA-5389840;Reactome: R-HSA-1268020;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial protein import";"Mitochondrial translation initiation";"Mitochondrial translation termination"
Lalb_10062	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
Lalb_04777	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_13116	6	MetaCyc: PWY-7356;Reactome: R-HSA-196819;MetaCyc: PWY-6898;MetaCyc: PWY-6908;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6907	"Thiamine salvage IV (yeast)";"Vitamin B1 (thiamin) metabolism";"Thiamine salvage III";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)"
Lalb_12589	3	MetaCyc: PWY-7800;Reactome: R-HSA-2514859;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)"
Lalb_01151	5	Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
Lalb_01760	6	Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72649	"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation"
Lalb_01710	3	Reactome: R-HSA-6782315;MetaCyc: PWY-6700;MetaCyc: PWY-8106	"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)"
Lalb_08035	5	Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-5221030	"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA"
Lalb_10842	8	MetaCyc: PWY-5738;KEGG: 00520+4.2.1.47;MetaCyc: PWY-5740;Reactome: R-HSA-6787639;MetaCyc: PWY-7573;MetaCyc: PWY-66;MetaCyc: PWY-5739;KEGG: 00051+4.2.1.47	"GDP-6-deoxy-D-talose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-L-colitose biosynthesis";"GDP-fucose biosynthesis";"GDP-mycosamine biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-D-perosamine biosynthesis";"Fructose and mannose metabolism"
Lalb_05138	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
Lalb_08132	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
Lalb_00189	12	Reactome: R-HSA-2408550;Reactome: R-HSA-174362;MetaCyc: PWY-5340;MetaCyc: PWY-6683;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6932;KEGG: 00920+2.7.1.25;KEGG: 00230+2.7.1.25;KEGG: 00230+2.7.7.4;KEGG: 00450+2.7.7.4;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5278	"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Transport and synthesis of PAPS";"Sulfate activation for sulfonation";"Assimilatory sulfate reduction III";"Sulfur metabolism";"Selenate reduction";"Sulfur metabolism";"Purine metabolism";"Purine metabolism";"Selenocompound metabolism";"Monobactam biosynthesis";"Sulfite oxidation III"
Lalb_13734	11	Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167200	"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
Lalb_06260	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
Lalb_13448	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
Lalb_05720	27	Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-159230	"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"ISG15 antiviral mechanism";"snRNP Assembly";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA"
Lalb_11517	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
Lalb_04380	5	Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic"
Lalb_00336	6	MetaCyc: PWY-7165;KEGG: 00030+3.1.1.17;MetaCyc: PWY-2221;KEGG: 00930+3.1.1.17;MetaCyc: PWY-5530;KEGG: 00053+3.1.1.17	"L-ascorbate biosynthesis VI (engineered pathway)";"Pentose phosphate pathway";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Caprolactam degradation";"Sorbitol biosynthesis II";"Ascorbate and aldarate metabolism"
Lalb_13781	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
Lalb_04133	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
Lalb_01796	4	Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-8943724	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription"
Lalb_01940	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
Lalb_11389	2	Reactome: R-HSA-8951664;Reactome: R-HSA-6798695	"Neddylation";"Neutrophil degranulation"
Lalb_01733	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
Lalb_04752	1	Reactome: R-HSA-611105	"Respiratory electron transport"
Lalb_00346	12	Reactome: R-HSA-982772;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826;Reactome: R-HSA-177929;Reactome: R-HSA-193692;Reactome: R-HSA-5362798;Reactome: R-HSA-2691232;Reactome: R-HSA-1442490;Reactome: R-HSA-75893;Reactome: R-HSA-2644606;Reactome: R-HSA-1251985	"Growth hormone receptor signaling";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Signaling by EGFR";"Regulated proteolysis of p75NTR";"Release of Hh-Np from the secreting cell";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Collagen degradation";"TNF signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nuclear signaling by ERBB4"
Lalb_07033	2	Reactome: R-HSA-442982;Reactome: R-HSA-5673001	"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade"
Lalb_09083	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
Lalb_08835	57	Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-6798695;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-202424;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-5607761;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-9010553;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-1236974;Reactome: R-HSA-69017;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-187577;Reactome: R-HSA-8939902	"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neutrophil degranulation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Downstream TCR signaling";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Interleukin-1 signaling";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"Regulation of expression of SLITs and ROBOs";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER-Phagosome pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Degradation of AXIN";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity"
Lalb_13750	2	KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
Lalb_06601	6	Reactome: R-HSA-204005;Reactome: R-HSA-416993;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPII-mediated vesicle transport";"Trafficking of GluR2-containing AMPA receptors";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
Lalb_06984	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
Lalb_01020	16	KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.4;MetaCyc: PWY-5392;MetaCyc: PWY-5749;KEGG: 00020+6.2.1.4;MetaCyc: PWY-6728;MetaCyc: PWY-5537;MetaCyc: PWY-5538;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5913;KEGG: 00660+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-7384;Reactome: R-HSA-71403	"Propanoate metabolism";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Reductive TCA cycle II";"Itaconate degradation";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Pyruvate fermentation to acetate V";"Pyruvate fermentation to acetate VI";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)"
Lalb_09721	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
Lalb_14538	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_01693	2	Reactome: R-HSA-1482798;Reactome: R-HSA-1268020	"Acyl chain remodeling of CL";"Mitochondrial protein import"
Lalb_03186	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_10546	7	MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25;MetaCyc: PWY-2301;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-4702;Reactome: R-HSA-1855183	"D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol"
Lalb_13575	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
Lalb_08666	1	Reactome: R-HSA-8951664	"Neddylation"
Lalb_00774	7	Reactome: R-HSA-163210;Reactome: R-HSA-8949613;Reactome: R-HSA-1268020;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-2151201;MetaCyc: PWY-7980	"Formation of ATP by chemiosmotic coupling";"Cristae formation";"Mitochondrial protein import";"Photosynthesis";"Oxidative phosphorylation";"Transcriptional activation of mitochondrial biogenesis";"ATP biosynthesis"
Lalb_00686	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
Lalb_08672	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
Lalb_02710	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
Lalb_03307	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
Lalb_07492	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
Lalb_06835	4	Reactome: R-HSA-4420097;Reactome: R-HSA-8849471;Reactome: R-HSA-2029482;Reactome: R-HSA-164944	"VEGFA-VEGFR2 Pathway";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Regulation of actin dynamics for phagocytic cup formation";"Nef and signal transduction"
Lalb_07872	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
Lalb_07058	5	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-201722;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of the beta-catenin:TCF transactivating complex";"Formation of RNA Pol II elongation complex"
Lalb_05727	7	MetaCyc: PWY-6855;MetaCyc: PWY-8004;MetaCyc: PWY-5514;Reactome: R-HSA-71336;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906;KEGG: 00030+3.1.1.31	"Chitin degradation I (archaea)";"Entner-Doudoroff pathway I";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Pentose phosphate pathway";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Pentose phosphate pathway"
Lalb_10077	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
Lalb_06211	16	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-156902	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation"
Lalb_08958	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
Lalb_11463	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
Lalb_01425	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
Lalb_14517	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
Lalb_03313	4	Reactome: R-HSA-1632852;Reactome: R-HSA-936440;Reactome: R-HSA-5205685;Reactome: R-HSA-8934903	"Macroautophagy";"Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy";"Receptor Mediated Mitophagy"
Lalb_06344	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
Lalb_14705	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
Lalb_14560	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
Lalb_12115	2	Reactome: R-HSA-1268020;Reactome: R-HSA-6803204	"Mitochondrial protein import";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
Lalb_13210	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
Lalb_09075	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
Lalb_08172	1	KEGG: 00906+1.23.5.1	"Carotenoid biosynthesis"
Lalb_12563	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
Lalb_00758	12	Reactome: R-HSA-76071;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-1834949;Reactome: R-HSA-427413;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73863;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"Cytosolic sensors of pathogen-associated DNA";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
Lalb_00741	9	Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-5674135;Reactome: R-HSA-8943724;Reactome: R-HSA-6798695;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897	"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"MAP2K and MAPK activation";"Regulation of PTEN gene transcription";"Neutrophil degranulation";"mTORC1-mediated signalling";"Macroautophagy";"TP53 Regulates Metabolic Genes"
Lalb_07474	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
Lalb_02722	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
Lalb_09542	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
Lalb_03166	13	MetaCyc: PWY-5497;MetaCyc: PWY-1722;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-2161;MetaCyc: PWY-2201;MetaCyc: PWY-5030;KEGG: 00720+6.3.4.3;Reactome: R-HSA-196757;KEGG: 00670+6.3.4.3;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-3841;MetaCyc: PWY-6613;MetaCyc: PWY-7909	"Purine nucleobases degradation II (anaerobic)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Folate polyglutamylation";"Folate transformations I";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"One carbon pool by folate";"One carbon pool by folate";"Folate transformations II (plants)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)"
Lalb_06270	31	Reactome: R-HSA-75105;MetaCyc: PWY-8012;MetaCyc: PWY-7388;MetaCyc: PWYG-321;MetaCyc: PWY-7746;MetaCyc: PWY-6799;Reactome: R-HSA-163765;MetaCyc: PWY-5366;MetaCyc: PWY-8049;MetaCyc: PWY-5367;MetaCyc: PWY-7858;MetaCyc: PWY-5142;MetaCyc: PWY-5994;Reactome: R-HSA-9029558;MetaCyc: PWY-6519;MetaCyc: PWY-5971;MetaCyc: PWY-7664;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6282;MetaCyc: PWY-7723;MetaCyc: PWY-6113;MetaCyc: PWY-5973;MetaCyc: PWY-8047;MetaCyc: PWY-5989;Reactome: R-HSA-2426168;MetaCyc: PWY-5147;MetaCyc: PWY-7663;MetaCyc: PWY-4381;Reactome: R-HSA-199220;MetaCyc: PWY-5966-1;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14	"Fatty acyl-CoA biosynthesis";"Mupirocin biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"ChREBP activates metabolic gene expression";"Palmitoleate biosynthesis II (plants and bacteria)";"Pederin biosynthesis";"Petroselinate biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Acyl-[acyl-carrier protein] thioesterase pathway";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"8-amino-7-oxononanoate biosynthesis I";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Oleate biosynthesis IV (anaerobic)";"Biotin metabolism";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Bacterial bioluminescence";"Superpathway of mycolate biosynthesis";"Cis-vaccenate biosynthesis";"Bryostatin biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"Oleate biosynthesis I (plants)";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Vitamin B5 (pantothenate) metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis"
Lalb_06249	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
Lalb_10088	56	Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-174113;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-174154;Reactome: R-HSA-211733	"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Regulation of RAS by GAPs";"Degradation of AXIN";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"SCF-beta-TrCP mediated degradation of Emi1";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Interleukin-1 signaling";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation"
Lalb_07922	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
Lalb_08155	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_00065	4	KEGG: 00520+2.7.1.59;Reactome: R-HSA-446210;MetaCyc: PWY-6517;MetaCyc: PWY-6906	"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II";"Chitin derivatives degradation"
Lalb_09372	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
Lalb_05197	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
Lalb_07486	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
Lalb_08705	5	MetaCyc: PWY-5653;MetaCyc: PWY-5381;Reactome: R-HSA-196807;MetaCyc: PWY-7761;KEGG: 00760+2.7.7.18	"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism"
Lalb_11797	3	Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
Lalb_13910	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
Lalb_10331	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)"
Lalb_11616	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
Lalb_10307	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
Lalb_04434	1	Reactome: R-HSA-1483148	"Synthesis of PG"
Lalb_04805	4	KEGG: 00260+4.2.1.22;Reactome: R-HSA-1614603;KEGG: 00270+4.2.1.22;MetaCyc: PWY-801	"Glycine, serine and threonine metabolism";"Cysteine formation from homocysteine";"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion"
Lalb_12116	11	MetaCyc: PWY-5381;MetaCyc: PWY-5695;MetaCyc: PWY-6596;MetaCyc: PWY-6606;MetaCyc: PWY-6608;MetaCyc: PWY-7185;KEGG: 00230+3.1.3.5;KEGG: 00760+3.1.3.5;MetaCyc: PWY-7821;MetaCyc: PWY-6607;KEGG: 00240+3.1.3.5	"Pyridine nucleotide cycling (plants)";"Inosine 5'-phosphate degradation";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III";"UTP and CTP dephosphorylation I";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Tunicamycin biosynthesis";"Guanosine nucleotides degradation I";"Pyrimidine metabolism"
Lalb_05392	1	Reactome: R-HSA-156588	"Glucuronidation"
Lalb_07351	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_03392	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
Lalb_03028	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
Lalb_02452	1	Reactome: R-HSA-1483191	"Synthesis of PC"
Lalb_01085	13	Reactome: R-HSA-6798695;Reactome: R-HSA-4085001;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23;Reactome: R-HSA-1660662;Reactome: R-HSA-4341670;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2206308;Reactome: R-HSA-2022857;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23	"Neutrophil degranulation";"Sialic acid metabolism";"Galactose metabolism";"HS-GAG degradation";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis";"Other glycan degradation";"MPS IV - Morquio syndrome B";"Keratan sulfate degradation";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series"
Lalb_10253	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
Lalb_04424	16	Reactome: R-HSA-176407;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-176412;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-176409;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-8853884	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Transcriptional Regulation by VENTX"
Lalb_08512	7	MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-5469	"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Sesamin biosynthesis"
Lalb_01184	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
Lalb_10737	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
Lalb_06776	6	Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-429958	"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease"
Lalb_12444	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
Lalb_01860	14	Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-5687128;Reactome: R-HSA-168333;Reactome: R-HSA-9634638;Reactome: R-HSA-3769402;Reactome: R-HSA-2467813;Reactome: R-HSA-2173788;Reactome: R-HSA-450520;Reactome: R-HSA-69273;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MAPK6/MAPK4 signaling";"NEP/NS2 Interacts with the Cellular Export Machinery";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Deactivation of the beta-catenin transactivating complex";"Separation of Sister Chromatids";"Downregulation of TGF-beta receptor signaling";"HuR (ELAVL1) binds and stabilizes mRNA";"Cyclin A/B1/B2 associated events during G2/M transition";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
Lalb_06277	13	Reactome: R-HSA-8856825;Reactome: R-HSA-167590;Reactome: R-HSA-2132295;Reactome: R-HSA-8856828;Reactome: R-HSA-177504;Reactome: R-HSA-5099900;Reactome: R-HSA-8964038;Reactome: R-HSA-3928665;Reactome: R-HSA-8866427;Reactome: R-HSA-5140745;Reactome: R-HSA-437239;Reactome: R-HSA-182218;Reactome: R-HSA-416993	"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"MHC class II antigen presentation";"Clathrin-mediated endocytosis";"Retrograde neurotrophin signalling";"WNT5A-dependent internalization of FZD4";"LDL clearance";"EPH-ephrin mediated repulsion of cells";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Recycling pathway of L1";"Nef Mediated CD8 Down-regulation";"Trafficking of GluR2-containing AMPA receptors"
Lalb_03121	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
Lalb_03013	2	Reactome: R-HSA-446199;KEGG: 00510+3.6.1.43	"Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis"
Lalb_10383	14	KEGG: 00720+1.3.5.1;MetaCyc: PWY-6728;KEGG: 00020+1.3.5.1;MetaCyc: PWY-5690;KEGG: 00650+1.3.5.1;KEGG: 00190+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-6969;MetaCyc: PWY-561;Reactome: R-HSA-71403;MetaCyc: PWY-3781;MetaCyc: PWY-7254;MetaCyc: PWY-7279;Reactome: R-HSA-611105	"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Butanoate metabolism";"Oxidative phosphorylation";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citric acid cycle (TCA cycle)";"Aerobic respiration I (cytochrome c)";"TCA cycle VII (acetate-producers)";"Aerobic respiration II (cytochrome c) (yeast)";"Respiratory electron transport"
Lalb_08277	2	Reactome: R-HSA-5663220;Reactome: R-HSA-376176	"RHO GTPases Activate Formins";"Signaling by ROBO receptors"
Lalb_08617	4	Reactome: R-HSA-947581;MetaCyc: PWY-7887;KEGG: 00790+2.8.1.12;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
Lalb_01728	3	KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491	"Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation"
Lalb_05418	2	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
Lalb_07182	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_04570	24	Reactome: R-HSA-416482;Reactome: R-HSA-416476;Reactome: R-HSA-392451;Reactome: R-HSA-392170;Reactome: R-HSA-8964315;Reactome: R-HSA-6814122;Reactome: R-HSA-428930;Reactome: R-HSA-420092;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-9009391;Reactome: R-HSA-8964616;Reactome: R-HSA-202040;Reactome: R-HSA-432040;Reactome: R-HSA-381676;Reactome: R-HSA-500657;Reactome: R-HSA-418594;Reactome: R-HSA-392851;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-4086398;Reactome: R-HSA-418217;Reactome: R-HSA-400042;Reactome: R-HSA-418555	"G alpha (12/13) signalling events";"G alpha (q) signalling events";"G beta:gamma signalling through PI3Kgamma";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through BTK";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Thromboxane signalling through TP receptor";"Glucagon-type ligand receptors";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through CDC42";"G-protein activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Presynaptic function of Kainate receptors";"G alpha (i) signalling events";"Prostacyclin signalling through prostacyclin receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"Ca2+ pathway";"G beta:gamma signalling through PLC beta";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (s) signalling events"
Lalb_01215	6	Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72706	"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit"
Lalb_11476	1	Reactome: R-HSA-6798163	"Choline catabolism"
Lalb_03882	4	Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-422085	"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin"
Lalb_02094	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
Lalb_05128	3	Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-390471	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Association of TriC/CCT with target proteins during biosynthesis"
Lalb_13139	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
Lalb_10547	7	Reactome: R-HSA-1855183;MetaCyc: PWY-2301;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363	"Synthesis of IP2, IP, and Ins in the cytosol";"Myo-inositol biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Phytate degradation I";"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation"
Lalb_00104	4	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
Lalb_01423	8	MetaCyc: PWY-7524;MetaCyc: PWY-7391;MetaCyc: PWY-922;KEGG: 00900+1.1.1.34;Reactome: R-HSA-2426168;MetaCyc: PWY-6174;Reactome: R-HSA-1989781;Reactome: R-HSA-191273	"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway II (archaea)";"PPARA activates gene expression";"Cholesterol biosynthesis"
Lalb_05974	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
Lalb_13096	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
Lalb_02999	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_00932	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
Lalb_06796	4	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379716;Reactome: R-HSA-379726	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation"
Lalb_14259	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus"
Lalb_03447	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_07917	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_05707	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
Lalb_05890	14	KEGG: 00290+2.6.1.42;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5076;MetaCyc: PWY-5101;MetaCyc: PWY-5057;KEGG: 00770+2.6.1.42;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5108;MetaCyc: PWY-5104;MetaCyc: PWY-5103;MetaCyc: PWY-5078;KEGG: 00280+2.6.1.42;MetaCyc: PWY-7767;Reactome: R-HSA-70895	"Valine, leucine and isoleucine biosynthesis";"Cysteine and methionine metabolism";"L-leucine degradation III";"L-isoleucine biosynthesis II";"L-valine degradation II";"Pantothenate and CoA biosynthesis";"Glucosinolate biosynthesis";"L-isoleucine biosynthesis V";"L-isoleucine biosynthesis IV";"L-isoleucine biosynthesis III";"L-isoleucine degradation II";"Valine, leucine and isoleucine degradation";"L-leucine degradation IV (Stickland reaction)";"Branched-chain amino acid catabolism"
Lalb_10302	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_03513	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
Lalb_01325	2	Reactome: R-HSA-1268020;Reactome: R-HSA-611105	"Mitochondrial protein import";"Respiratory electron transport"
Lalb_10926	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
Lalb_02086	7	KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-4702;Reactome: R-HSA-1855183;KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363	"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation"
Lalb_02676	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
Lalb_04158	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
Lalb_10843	57	Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-202424;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-6798695;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-382556	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Regulation of PTEN stability and activity";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Regulation of RAS by GAPs";"Degradation of AXIN";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Hedgehog 'on' state";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"Downstream TCR signaling";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Neutrophil degranulation";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport"
Lalb_09872	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
Lalb_01349	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
Lalb_12778	2	Reactome: R-HSA-6782315;Reactome: R-HSA-6787450	"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion"
Lalb_12498	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
Lalb_02028	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
Lalb_05412	3	Reactome: R-HSA-2514859;KEGG: 00310+2.1.1.60;Reactome: R-HSA-8876725	"Inactivation, recovery and regulation of the phototransduction cascade";"Lysine degradation";"Protein methylation"
Lalb_10545	16	Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
Lalb_06425	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
Lalb_10670	1	Reactome: R-HSA-156588	"Glucuronidation"
Lalb_01065	5	Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757	"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation"
Lalb_01649	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_05001	13	MetaCyc: PWY-5537;MetaCyc: PWY-5690;MetaCyc: PWY-6728;KEGG: 00640+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00720+6.2.1.5;Reactome: R-HSA-71403;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5913;MetaCyc: PWY-6969	"Pyruvate fermentation to acetate V";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
Lalb_11480	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
Lalb_12507	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
Lalb_09100	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
Lalb_08025	19	Reactome: R-HSA-194840;Reactome: R-HSA-389359;Reactome: R-HSA-525793;Reactome: R-HSA-5663213;Reactome: R-HSA-418885;Reactome: R-HSA-2029482;Reactome: R-HSA-5687128;Reactome: R-HSA-428543;Reactome: R-HSA-5627123;Reactome: R-HSA-182971;Reactome: R-HSA-114604;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-4420097;Reactome: R-HSA-3928662;Reactome: R-HSA-5625970;Reactome: R-HSA-8964616;Reactome: R-HSA-983231;Reactome: R-HSA-8950505	"Rho GTPase cycle";"CD28 dependent Vav1 pathway";"Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"DCC mediated attractive signaling";"Regulation of actin dynamics for phagocytic cup formation";"MAPK6/MAPK4 signaling";"Inactivation of CDC42 and RAC1";"RHO GTPases activate PAKs";"EGFR downregulation";"GPVI-mediated activation cascade";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"VEGFA-VEGFR2 Pathway";"EPHB-mediated forward signaling";"RHO GTPases activate KTN1";"G beta:gamma signalling through CDC42";"Factors involved in megakaryocyte development and platelet production";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
Lalb_06522	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
Lalb_07296	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
Lalb_00192	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
Lalb_01645	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
Lalb_01577	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
Lalb_04056	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_07490	1	Reactome: R-HSA-71288	"Creatine metabolism"
Lalb_09362	6	Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-399997;Reactome: R-HSA-428930	"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor"
Lalb_04551	1	Reactome: R-HSA-1296061	"HCN channels"
Lalb_04389	2	Reactome: R-HSA-191859;Reactome: R-HSA-6807505	"snRNP Assembly";"RNA polymerase II transcribes snRNA genes"
Lalb_07904	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
Lalb_12813	5	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-432722;Reactome: R-HSA-6798695	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis";"Neutrophil degranulation"
Lalb_10895	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
Lalb_09177	4	Reactome: R-HSA-8934903;Reactome: R-HSA-1632852;Reactome: R-HSA-936440;Reactome: R-HSA-5205685	"Receptor Mediated Mitophagy";"Macroautophagy";"Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy"
Lalb_02048	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
Lalb_13846	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
Lalb_03477	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
Lalb_07407	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
Lalb_03690	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
Lalb_10437	11	Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-174437;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-69166;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693607	"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Removal of the Flap Intermediate from the C-strand";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Removal of the Flap Intermediate";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends"
Lalb_06521	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_03933	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_10306	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
Lalb_09630	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
Lalb_11913	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
Lalb_08369	8	KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1	"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis"
Lalb_06431	2	Reactome: R-HSA-8949664;Reactome: R-HSA-1268020	"Processing of SMDT1";"Mitochondrial protein import"
Lalb_01585	4	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
Lalb_09125	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
Lalb_13785	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
Lalb_13851	7	Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-166208	"Macroautophagy";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"mTORC1-mediated signalling"
Lalb_10215	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
Lalb_02899	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
Lalb_10829	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
Lalb_09238	6	Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-72163	"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Splicing - Major Pathway"
Lalb_01575	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
Lalb_00378	4	Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
Lalb_04320	31	MetaCyc: PWY-5366;MetaCyc: PWY-8049;MetaCyc: PWY-5367;MetaCyc: PWY-5142;MetaCyc: PWY-7858;MetaCyc: PWY-6519;Reactome: R-HSA-9029558;MetaCyc: PWY-5994;MetaCyc: PWY-8012;MetaCyc: PWY-7388;MetaCyc: PWYG-321;Reactome: R-HSA-75105;MetaCyc: PWY-7746;Reactome: R-HSA-163765;MetaCyc: PWY-6799;MetaCyc: PWY-5989;MetaCyc: PWY-8047;MetaCyc: PWY-4381;MetaCyc: PWY-5147;MetaCyc: PWY-7663;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;MetaCyc: PWY-5966-1;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7664;MetaCyc: PWY-5971;MetaCyc: PWY-6282;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6113;MetaCyc: PWY-5973;MetaCyc: PWY-7723	"Palmitoleate biosynthesis II (plants and bacteria)";"Pederin biosynthesis";"Petroselinate biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"(5Z)-dodecenoate biosynthesis II";"8-amino-7-oxononanoate biosynthesis I";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Mupirocin biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"";"Fatty acyl-CoA biosynthesis";"Mycobacterial sulfolipid biosynthesis";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (plant mitochondria)";"Stearate biosynthesis II (bacteria and plants)";"Bryostatin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Oleate biosynthesis I (plants)";"Gondoate biosynthesis (anaerobic)";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Biotin metabolism";"Superpathway of mycolate biosynthesis";"Cis-vaccenate biosynthesis";"Bacterial bioluminescence"
Lalb_11642	5	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9639288	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"Amino acids regulate mTORC1"
Lalb_13107	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
Lalb_08648	57	Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-174113;Reactome: R-HSA-5632684;Reactome: R-HSA-532668;Reactome: R-HSA-5610785;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783	"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Degradation of AXIN";"Regulation of RAS by GAPs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Hedgehog 'on' state";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"GLI3 is processed to GLI3R by the proteasome";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome"
Lalb_04924	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
Lalb_06881	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
Lalb_06407	13	Reactome: R-HSA-1855204;Reactome: R-HSA-2871809;MetaCyc: PWY-6367;Reactome: R-HSA-2029485;Reactome: R-HSA-2424491;Reactome: R-HSA-2871796;MetaCyc: PWY-8052;MetaCyc: PWY-7039;Reactome: R-HSA-9027277;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;Reactome: R-HSA-202433;KEGG: 00562+3.1.4.11	"Synthesis of IP3 and IP4 in the cytosol";"FCERI mediated Ca+2 mobilization";"D-myo-inositol-5-phosphate metabolism";"Role of phospholipids in phagocytosis";"DAP12 signaling";"FCERI mediated MAPK activation";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Erythropoietin activates Phospholipase C gamma (PLCG)";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Generation of second messenger molecules";"Inositol phosphate metabolism"
Lalb_13223	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
Lalb_05532	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
Lalb_08176	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
Lalb_01497	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
Lalb_13137	10	KEGG: 04150+2.7.1.153;KEGG: 04070+2.7.1.153;KEGG: 05165+2.7.1.153;KEGG: 05163+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 04151+2.7.1.153;KEGG: 00562+2.7.1.153;MetaCyc: PWY-6352;Reactome: R-HSA-9027276;KEGG: 05170+2.7.1.153	"mTOR signaling pathway";"Phosphatidylinositol signaling system";"Human papillomavirus infection";"Human cytomegalovirus infection";"Synthesis of PIPs at the plasma membrane";"PI3K-Akt signaling pathway";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human immunodeficiency virus 1 infection"
Lalb_08934	13	MetaCyc: PWY-5392;MetaCyc: PWY-561;MetaCyc: PWY-5913;MetaCyc: PWY-6969;MetaCyc: PWY-8086;Reactome: R-HSA-71403;KEGG: 00620+4.2.1.2;MetaCyc: PWY-7254;MetaCyc: PWY-7384;KEGG: 00020+4.2.1.2;KEGG: 00720+4.2.1.2;MetaCyc: PWY-6728;MetaCyc: PWY-5690	"Reductive TCA cycle II";"Superpathway of glyoxylate cycle and fatty acid degradation";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citric acid cycle (TCA cycle)";"Pyruvate metabolism";"TCA cycle VII (acetate-producers)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"TCA cycle II (plants and fungi)"
Lalb_09044	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
Lalb_00596	1	Reactome: R-HSA-1632852	"Macroautophagy"
Lalb_12520	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
Lalb_04697	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
Lalb_00290	6	Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813	"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids"
Lalb_03625	11	MetaCyc: PWY-381;KEGG: 00910+6.3.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-210455;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6549;KEGG: 00220+6.3.1.2;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6963;MetaCyc: PWY-6964;MetaCyc: PWY-5675	"Nitrate reduction II (assimilatory)";"Nitrogen metabolism";"Glutamate and glutamine metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Alanine, aspartate and glutamate metabolism";"L-glutamine biosynthesis III";"Arginine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle I";"Ammonia assimilation cycle II";"Nitrate reduction V (assimilatory)"
Lalb_03937	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
Lalb_02403	3	MetaCyc: PWY-7426;KEGG: 00510+2.4.1.144;Reactome: R-HSA-975574	"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Reactions specific to the hybrid N-glycan synthesis pathway"
Lalb_07399	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
Lalb_07975	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
Lalb_12668	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
Lalb_07168	1	Reactome: R-HSA-189200	"Cellular hexose transport"
Lalb_08918	57	Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-195253;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-174113;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-6798695;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442	"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"Neutrophil degranulation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of AXIN";"Regulation of RAS by GAPs"
Lalb_02115	24	Reactome: R-HSA-6811434;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276	"COPI-dependent Golgi-to-ER retrograde traffic";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Recycling pathway of L1";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint"
Lalb_09856	16	Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
Lalb_02604	5	KEGG: 00240+6.3.4.2;MetaCyc: PWY-7177;Reactome: R-HSA-499943;MetaCyc: PWY-7185;MetaCyc: PWY-7176	"Pyrimidine metabolism";"UTP and CTP dephosphorylation II";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation I";"UTP and CTP de novo biosynthesis"
Lalb_00507	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
Lalb_09490	52	Reactome: R-HSA-77075;Reactome: R-HSA-9018519;Reactome: R-HSA-72086;Reactome: R-HSA-749476;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-73780;Reactome: R-HSA-167290;Reactome: R-HSA-5601884;Reactome: R-HSA-112382;Reactome: R-HSA-8851708;Reactome: R-HSA-167161;Reactome: R-HSA-73863;Reactome: R-HSA-73779;Reactome: R-HSA-203927;Reactome: R-HSA-5578749;Reactome: R-HSA-167160;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-73980;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167162;Reactome: R-HSA-5617472;Reactome: R-HSA-427413;Reactome: R-HSA-168325;Reactome: R-HSA-76061;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-76066;Reactome: R-HSA-6781823;Reactome: R-HSA-73776;Reactome: R-HSA-6803529;Reactome: R-HSA-167172;Reactome: R-HSA-73772;Reactome: R-HSA-6782135;Reactome: R-HSA-1834949;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-6782210;Reactome: R-HSA-72203;Reactome: R-HSA-73762;Reactome: R-HSA-72163;Reactome: R-HSA-5250924;Reactome: R-HSA-76071;Reactome: R-HSA-167243;Reactome: R-HSA-76042;Reactome: R-HSA-167287;Reactome: R-HSA-6807505	"RNA Pol II CTD phosphorylation and interaction with CE";"Estrogen-dependent gene expression";"mRNA Capping";"RNA Polymerase III Abortive And Retractive Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase III Chain Elongation";"Pausing and recovery of HIV elongation";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of RNA Pol II elongation complex";"Signaling by FGFR2 IIIa TM";"HIV Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"MicroRNA (miRNA) biogenesis";"Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II HIV Promoter Escape";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NoRC negatively regulates rRNA expression";"Viral Messenger RNA Synthesis";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Promoter Escape";"FGFR2 alternative splicing";"Transcription of the HIV genome";"RNA Polymerase I Promoter Escape";"Dual incision in TC-NER";"Cytosolic sensors of pathogen-associated DNA";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase I Transcription Initiation";"mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes"
Lalb_03114	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
Lalb_04132	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
Lalb_02195	13	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
Lalb_14018	22	MetaCyc: PWY-6958;KEGG: 00062+4.2.1.134;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7053;MetaCyc: PWY-7606;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-5353;MetaCyc: PWY-8041;MetaCyc: PWY-7726;MetaCyc: PWY-7601;MetaCyc: PWY-7592;MetaCyc: PWY-7727;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7728;MetaCyc: PWY-7725;MetaCyc: PWY-7049;MetaCyc: PWY-7035	"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Fatty acid elongation";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"(9Z)-tricosene biosynthesis"
Lalb_13482	2	Reactome: R-HSA-167827;Reactome: R-HSA-167826	"The proton buffering model";"The fatty acid cycling model"
Lalb_00749	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
Lalb_02986	1	Reactome: R-HSA-8951664	"Neddylation"
Lalb_11673	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
Lalb_04611	14	MetaCyc: PWY-1622;MetaCyc: PWY-6142;MetaCyc: PWY-7003;MetaCyc: PWY-6901;MetaCyc: PWY-8004;MetaCyc: PWY-2221;MetaCyc: PWY-5484;MetaCyc: PWY-5723;MetaCyc: PWY-7218;MetaCyc: PWY-7124;KEGG: 00010+4.2.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-6886;KEGG: 00680+4.2.1.11	"Formaldehyde assimilation I (serine pathway)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway I";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"Rubisco shunt";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Ethylene biosynthesis V (engineered)";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Methane metabolism"
Lalb_02170	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
Lalb_09576	57	Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-6798695;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-69017;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-5358346	"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Downstream TCR signaling";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neutrophil degranulation";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"Degradation of AXIN";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"CDK-mediated phosphorylation and removal of Cdc6";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis"
Lalb_09662	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
Lalb_05939	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
Lalb_08653	6	Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68962	"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Activation of the pre-replicative complex"
Lalb_03433	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
Lalb_09317	2	Reactome: R-HSA-2024096;Reactome: R-HSA-2206307	"HS-GAG degradation";"MPS IIIA - Sanfilippo syndrome A"
Lalb_10974	4	MetaCyc: PWY-7546;MetaCyc: PWY-6482;Reactome: R-HSA-8849175;Reactome: R-HSA-5358493	"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)";"Threonine catabolism";"Synthesis of diphthamide-EEF2"
Lalb_08929	5	MetaCyc: PWY-7426;KEGG: 00513+2.4.1.68;KEGG: 00510+2.4.1.68;Reactome: R-HSA-975578;KEGG: 00533+2.4.1.68	"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Glycosaminoglycan biosynthesis - keratan sulfate"
Lalb_02157	13	KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52	"Glycosaminoglycan degradation";"Other glycan degradation";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Hyaluronan uptake and degradation";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis"
Lalb_04559	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
Lalb_07005	1	Reactome: R-HSA-211981	"Xenobiotics"
Lalb_10897	1	Reactome: R-HSA-70350	"Fructose catabolism"
Lalb_01702	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_10782	5	Reactome: R-HSA-70688;KEGG: 00250+1.2.1.88;KEGG: 00330+1.2.1.88;MetaCyc: PWY-6853;Reactome: R-HSA-389661	"Proline catabolism";"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism";"Ethylene biosynthesis II (microbes)";"Glyoxylate metabolism and glycine degradation"
Lalb_10262	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_03874	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
Lalb_10523	13	Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-192823	"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Viral mRNA Translation"
Lalb_07786	4	Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-77595	"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs"
Lalb_11051	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
Lalb_02001	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_09154	12	Reactome: R-HSA-73772;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-73863;Reactome: R-HSA-76061;Reactome: R-HSA-427413;Reactome: R-HSA-73980	"RNA Polymerase I Promoter Escape";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Termination"
Lalb_01899	5	KEGG: 00670+1.5.1.20;MetaCyc: PWY-3841;MetaCyc: PWY-2201;KEGG: 00720+1.5.1.20;Reactome: R-HSA-196757	"One carbon pool by folate";"Folate transformations II (plants)";"Folate transformations I";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines"
Lalb_11308	6	KEGG: 00520+1.1.1.22;KEGG: 00040+1.1.1.22;MetaCyc: PWY-7820;MetaCyc: PWY-7346;KEGG: 00053+1.1.1.22;Reactome: R-HSA-173599	"Amino sugar and nucleotide sugar metabolism";"Pentose and glucuronate interconversions";"Teichuronic acid biosynthesis (B. subtilis 168)";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Ascorbate and aldarate metabolism";"Formation of the active cofactor, UDP-glucuronate"
Lalb_00894	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
Lalb_03482	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Intra-Golgi traffic"
Lalb_02862	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
Lalb_08532	15	Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-9603505;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167200	"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"NTRK3 as a dependence receptor";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
Lalb_05155	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
Lalb_02361	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
Lalb_12055	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
Lalb_06477	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
Lalb_09795	7	KEGG: 00600+2.4.1.80;MetaCyc: PWY-7839;MetaCyc: PWY-7841;MetaCyc: PWY-7836;MetaCyc: PWY-5129;MetaCyc: PWY-7838;Reactome: R-HSA-1660662	"Sphingolipid metabolism";"Lacto-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Globo-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism"
Lalb_01188	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
Lalb_09489	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
Lalb_08603	5	Reactome: R-HSA-5579006;MetaCyc: PWY-8043;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3;KEGG: 00270+6.3.2.3	"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Glutathione metabolism";"Cysteine and methionine metabolism"
Lalb_01134	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
Lalb_14009	3	Reactome: R-HSA-5628897;KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"TP53 Regulates Metabolic Genes";"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
Lalb_02562	19	MetaCyc: PWY-5690;MetaCyc: PWY-7115;Reactome: R-HSA-70263;KEGG: 00020+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00710+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-5392;MetaCyc: PWY-1622;MetaCyc: PWY-8086;KEGG: 00620+1.1.1.37;MetaCyc: PWY-6728;Reactome: R-HSA-71403;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-5913;KEGG: 00680+1.1.1.37;KEGG: 00720+1.1.1.37	"TCA cycle II (plants and fungi)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation in photosynthetic organisms";"Glyoxylate and dicarboxylate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Reductive TCA cycle II";"Formaldehyde assimilation I (serine pathway)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Cysteine and methionine metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Methane metabolism";"Carbon fixation pathways in prokaryotes"
Lalb_08175	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
Lalb_05514	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
Lalb_04909	13	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-6791226	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_07807	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
Lalb_05905	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
Lalb_10690	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
Lalb_08621	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
Lalb_05139	13	Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-1632852;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-5628897;Reactome: R-HSA-5218920;Reactome: R-HSA-9639288;Reactome: R-HSA-1257604;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-389357	"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"Macroautophagy";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"TP53 Regulates Metabolic Genes";"VEGFR2 mediated vascular permeability";"Amino acids regulate mTORC1";"PIP3 activates AKT signaling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"CD28 dependent PI3K/Akt signaling"
Lalb_10806	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
Lalb_11860	17	Reactome: R-HSA-5685938;Reactome: R-HSA-1221632;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3371453;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-6783310;Reactome: R-HSA-176187;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6796648;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693616	"HDR through Single Strand Annealing (SSA)";"Meiotic synapsis";"Relaxin signaling pathway";"Regulation of HSF1-mediated heat shock response";"mTOR signaling pathway";"Human cytomegalovirus infection";"Regulation of TP53 Activity through Phosphorylation";"Fanconi Anemia Pathway";"Activation of ATR in response to replication stress";"Thermogenesis";"PI3K-Akt signaling pathway";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Human papillomavirus infection";"TP53 Regulates Transcription of DNA Repair Genes";"Human immunodeficiency virus 1 infection";"Presynaptic phase of homologous DNA pairing and strand exchange"
Lalb_07981	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_09133	13	Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339	"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane"
Lalb_09912	6	MetaCyc: PWY-6123;KEGG: 00230+6.3.2.6;KEGG: 00230+4.1.1.21;Reactome: R-HSA-73817;MetaCyc: PWY-6124;MetaCyc: PWY-7234	"Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis III"
Lalb_09743	1	Reactome: R-HSA-156588	"Glucuronidation"
Lalb_12120	56	Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978	"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RAS by GAPs";"Degradation of AXIN";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)"
Lalb_08534	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
Lalb_12235	5	Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73772	"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape"
Lalb_07106	2	Reactome: R-HSA-70350;Reactome: R-HSA-168928	"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta"
Lalb_14111	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
Lalb_03804	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
Lalb_02402	7	KEGG: 00510+2.7.8.15;MetaCyc: PWY-5265;Reactome: R-HSA-446193;KEGG: 00550+2.7.8.13;Reactome: R-HSA-4549356;MetaCyc: PWY-6470;MetaCyc: PWY-6471	"N-Glycan biosynthesis";"Peptidoglycan biosynthesis II (staphylococci)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)"
Lalb_13002	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
Lalb_00707	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
Lalb_09148	1	Reactome: R-HSA-189200	"Cellular hexose transport"
Lalb_12137	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_05494	1	Reactome: R-HSA-1483166	"Synthesis of PA"
Lalb_04297	5	Reactome: R-HSA-917937;Reactome: R-HSA-5689603;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-2173789	"Iron uptake and transport";"UCH proteinases";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"TGF-beta receptor signaling activates SMADs"
Lalb_08234	5	Reactome: R-HSA-5620924;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Intraflagellar transport";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
Lalb_03555	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
Lalb_05359	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
Lalb_03706	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
Lalb_06911	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
Lalb_04475	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
Lalb_00583	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
Lalb_05923	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
Lalb_07586	33	Reactome: R-HSA-1169408;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-170822;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-141444;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-2467813;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-5619107	"ISG15 antiviral mechanism";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"Separation of Sister Chromatids";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"
Lalb_13659	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
Lalb_00122	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
Lalb_08641	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
Lalb_06815	4	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
Lalb_10938	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
Lalb_06602	11	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9614657;Reactome: R-HSA-163680;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"FOXO-mediated transcription of cell death genes";"AMPK inhibits chREBP transcriptional activation activity";"Human cytomegalovirus infection";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
Lalb_13985	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER"
Lalb_11472	1	Reactome: R-HSA-6798163	"Choline catabolism"
Lalb_10367	8	KEGG: 00220+6.3.4.5;MetaCyc: PWY-5;MetaCyc: PWY-4983;MetaCyc: PWY-5154;Reactome: R-HSA-70635;MetaCyc: PWY-4984;KEGG: 00250+6.3.4.5;MetaCyc: PWY-7400	"Arginine biosynthesis";"Canavanine biosynthesis";"Nitric oxide biosynthesis II (mammals)";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Urea cycle";"Urea cycle";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis IV (archaebacteria)"
Lalb_04552	14	MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-8041;Reactome: R-HSA-75876	"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs"
Lalb_03566	13	Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72764	"Viral mRNA Translation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination"
Lalb_03724	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
Lalb_01680	7	Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
Lalb_05767	3	Reactome: R-HSA-204174;Reactome: R-HSA-156590;Reactome: R-HSA-8963684	"Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation";"Tyrosine catabolism"
Lalb_00485	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
Lalb_13965	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
Lalb_06456	5	MetaCyc: PWY-6829;Reactome: R-HSA-196843;MetaCyc: PWY-7285;Reactome: R-HSA-6782861;MetaCyc: PWY-7286	"Trna methylation (yeast)";"Vitamin B2 (riboflavin) metabolism";"Methylwyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
Lalb_06348	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
Lalb_07084	16	Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72649	"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation"
Lalb_11192	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
Lalb_07098	7	KEGG: 00030+3.1.3.11;KEGG: 00051+3.1.3.11;KEGG: 00680+3.1.3.11;MetaCyc: PWY-5484;Reactome: R-HSA-70263;KEGG: 00710+3.1.3.11;KEGG: 00010+3.1.3.11	"Pentose phosphate pathway";"Fructose and mannose metabolism";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis"
Lalb_08627	8	Reactome: R-HSA-5083633;MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109	"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis"
Lalb_09309	57	Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-211733;Reactome: R-HSA-6798695;Reactome: R-HSA-174154;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-180585	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neutrophil degranulation";"APC/C:Cdc20 mediated degradation of Securin";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RAS by GAPs";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G"
Lalb_02185	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
Lalb_04584	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
Lalb_01971	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
Lalb_05286	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
Lalb_03204	11	Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-5689880;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847	"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"Ub-specific processing proteases";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones"
Lalb_08568	3	KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3	"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism"
Lalb_07569	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
Lalb_12081	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
Lalb_07117	15	MetaCyc: PWY-7218;MetaCyc: PWY-5723;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5484;MetaCyc: PWY-6886;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-6901;MetaCyc: PWY-6142;MetaCyc: PWY-2221;MetaCyc: PWY-8004;MetaCyc: PWY-7383;KEGG: 00230+2.7.1.40;KEGG: 00010+2.7.1.40	"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"Pyruvate metabolism";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"Anaerobic energy metabolism (invertebrates, cytosol)";"Purine metabolism";"Glycolysis / Gluconeogenesis"
Lalb_08147	13	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72706	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit"
Lalb_07154	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
Lalb_03542	9	MetaCyc: PWY-7003;MetaCyc: PWY-6901;KEGG: 00010+1.2.1.12;MetaCyc: PWY-8004;MetaCyc: PWY-5484;Reactome: R-HSA-70263;KEGG: 00710+1.2.1.12;MetaCyc: PWY-1042;Reactome: R-HSA-70171	"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Glycolysis"
Lalb_13299	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
Lalb_10771	1	Reactome: R-HSA-912446	"Meiotic recombination"
Lalb_11418	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
Lalb_05823	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
Lalb_06596	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
Lalb_09862	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
Lalb_06778	3	MetaCyc: PWY-6829;MetaCyc: PWY-7888;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol"
Lalb_03007	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
Lalb_09909	1	Reactome: R-HSA-611105	"Respiratory electron transport"
Lalb_06311	5	Reactome: R-HSA-6798695;MetaCyc: PWY-7185;KEGG: 00240+3.6.1.6;KEGG: 00230+3.6.1.6;MetaCyc: PWY-7210	"Neutrophil degranulation";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
Lalb_06887	5	Reactome: R-HSA-1912408;Reactome: R-HSA-1912399;Reactome: R-HSA-1912420;Reactome: R-HSA-350054;Reactome: R-HSA-5083630	"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Pre-NOTCH Processing in Golgi";"Notch-HLH transcription pathway";"Defective LFNG causes SCDO3"
Lalb_06307	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
Lalb_10548	7	MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-4702;Reactome: R-HSA-1855183	"D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol"
Lalb_02370	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_03223	19	Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-438066;Reactome: R-HSA-936837;Reactome: R-HSA-111932;Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-442982	"Ion homeostasis";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion transport by P-type ATPases";"CaMK IV-mediated phosphorylation of CREB";"Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"HSF1-dependent transactivation";"RAF activation";"Phase 0 - rapid depolarisation";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor"
Lalb_05420	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
Lalb_08739	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
Lalb_00201	3	Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-110320	"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH"
Lalb_13134	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
Lalb_10775	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
Lalb_06823	19	Reactome: R-HSA-8964046;Reactome: R-HSA-8964026;Reactome: R-HSA-8866423;Reactome: R-HSA-432142;Reactome: R-HSA-202733;Reactome: R-HSA-8856825;Reactome: R-HSA-381426;Reactome: R-HSA-3000484;Reactome: R-HSA-8963901;Reactome: R-HSA-8964038;Reactome: R-HSA-3000497;Reactome: R-HSA-8957275;Reactome: R-HSA-8964041;Reactome: R-HSA-5686938;Reactome: R-HSA-975634;Reactome: R-HSA-3000471;Reactome: R-HSA-8856828;Reactome: R-HSA-3000480;Reactome: R-HSA-8963888	"VLDL clearance";"Chylomicron clearance";"VLDL assembly";"Platelet sensitization by LDL";"Cell surface interactions at the vascular wall";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class F Receptors";"Chylomicron remodeling";"LDL clearance";"Scavenging by Class H Receptors";"Post-translational protein phosphorylation";"LDL remodeling";"Regulation of TLR by endogenous ligand";"Retinoid metabolism and transport";"Scavenging by Class B Receptors";"Clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"Chylomicron assembly"
Lalb_07370	1	Reactome: R-HSA-977443	"GABA receptor activation"
Lalb_10232	12	MetaCyc: PWY-7901;MetaCyc: PWY-6309;MetaCyc: PWY-6842;MetaCyc: PWY-6936;MetaCyc: PWY-801;MetaCyc: PWY-1187;MetaCyc: PWY-601;MetaCyc: PWY-2821;KEGG: 00270+4.4.1.13;Reactome: R-HSA-71240;KEGG: 00380+2.6.1.7;KEGG: 00450+4.4.1.13	"Glucosinolate biosynthesis from tyrosine";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glutathione-mediated detoxification II";"Seleno-amino acid biosynthesis (plants)";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from tryptophan";"Glucosinolate biosynthesis from phenylalanine";"Cysteine and methionine metabolism";"Tryptophan catabolism";"Tryptophan metabolism";"Selenocompound metabolism"
Lalb_01358	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
Lalb_13893	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
Lalb_14039	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
Lalb_08657	2	Reactome: R-HSA-201681;Reactome: R-HSA-3772470	"TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists"
Lalb_02915	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
Lalb_04062	7	Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
Lalb_02096	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
Lalb_08985	6	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-8939211;Reactome: R-HSA-5675221;Reactome: R-HSA-5693565;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"ESR-mediated signaling";"Negative regulation of MAPK pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
Lalb_04719	13	Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339	"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane"
Lalb_11151	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
Lalb_08543	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
Lalb_12456	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
Lalb_02880	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
Lalb_01416	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_08953	3	Reactome: R-HSA-2022928;KEGG: 00534+5.1.3.17;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)"
Lalb_13631	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
Lalb_03900	2	Reactome: R-HSA-72764;Reactome: R-HSA-156581	"Eukaryotic Translation Termination";"Methylation"
Lalb_11678	7	Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;Reactome: R-HSA-5083628;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-9010553;Reactome: R-HSA-5083633	"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"Regulation of expression of SLITs and ROBOs";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
Lalb_08226	26	Reactome: R-HSA-69166;Reactome: R-HSA-174414;Reactome: R-HSA-110314;Reactome: R-HSA-69205;Reactome: R-HSA-5358606;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5358565;Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-174417;Reactome: R-HSA-6804114;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-1362277;Reactome: R-HSA-174437;Reactome: R-HSA-4615885;Reactome: R-HSA-8866654;Reactome: R-HSA-5656169	"Removal of the Flap Intermediate";"Processive synthesis on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"G1/S-Specific Transcription";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching";"Processive synthesis on the lagging strand";"Telomere C-strand (Lagging Strand) Synthesis";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Transcription of E2F targets under negative control by DREAM complex";"Removal of the Flap Intermediate from the C-strand";"SUMOylation of DNA replication proteins";"E3 ubiquitin ligases ubiquitinate target proteins";"Termination of translesion DNA synthesis"
Lalb_12733	3	KEGG: 04070+3.1.3.78;MetaCyc: PWY-6368;MetaCyc: PWY-6367	"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism"
Lalb_06606	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
Lalb_14325	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
Lalb_04617	10	Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-9018519	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Estrogen-dependent gene expression"
Lalb_00953	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
Lalb_04348	3	MetaCyc: PWY-2161B;Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9	"Glutamate removal from folates";"Neutrophil degranulation";"Folate biosynthesis"
Lalb_12263	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_04261	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
Lalb_12977	2	Reactome: R-HSA-4641262;Reactome: R-HSA-196299	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade"
Lalb_13633	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
Lalb_06036	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_11672	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
Lalb_00479	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
Lalb_06329	17	MetaCyc: PWY-5532;MetaCyc: PWY-6627;Reactome: R-HSA-6798695;MetaCyc: PWY-7179;Reactome: R-HSA-74217;MetaCyc: PWY-5695;KEGG: 00230+2.4.2.1;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6644;MetaCyc: PWY-4202;MetaCyc: PWY-6620;MetaCyc: PWY-7179-1;MetaCyc: PWY-6611;Reactome: R-HSA-74259;MetaCyc: PWY-6609;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6608	"Nucleoside and nucleotide degradation (archaea)";"Salinosporamide A biosynthesis";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I";"Purine salvage";"Inosine 5'-phosphate degradation";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Arsenate detoxification I (mammalian)";"Guanine and guanosine salvage";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage V";"Purine catabolism";"Adenine and adenosine salvage III";"Pyrimidine metabolism";"Guanosine nucleotides degradation III"
Lalb_05999	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_11536	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
Lalb_10365	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_08230	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_08502	9	Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167161	"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation"
Lalb_10268	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
Lalb_04392	17	KEGG: 04658+3.1.3.16;Reactome: R-HSA-167246;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167287;Reactome: R-HSA-167243;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167242	"Th1 and Th2 cell differentiation";"Tat-mediated elongation of the HIV-1 transcript";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"T cell receptor signaling pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat"
Lalb_00261	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
Lalb_00113	57	Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-6798695;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-202424;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783	"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neutrophil degranulation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Downstream TCR signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome"
Lalb_05743	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
Lalb_09620	10	MetaCyc: PWY-5030;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;MetaCyc: PWY-1722;MetaCyc: PWY-5497;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613;MetaCyc: PWY-3841;MetaCyc: PWY-7909;Reactome: R-HSA-196757	"L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"Folate transformations I";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations II (plants)";"Formaldehyde oxidation VII (THF pathway)";"Metabolism of folate and pterines"
Lalb_12557	1	Reactome: R-HSA-176974	"Unwinding of DNA"
Lalb_01822	8	Reactome: R-HSA-70268;KEGG: 00270+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00640+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-8086;KEGG: 00620+1.1.1.27;KEGG: 00010+1.1.1.27	"Pyruvate metabolism";"Cysteine and methionine metabolism";"Pyruvate fermentation to (S)-lactate";"Propanoate metabolism";"Superpathway of glucose and xylose degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis"
Lalb_10060	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
Lalb_09451	4	Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295	"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
Lalb_00501	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
Lalb_09605	6	Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination"
Lalb_11264	14	Reactome: R-HSA-8854518;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-2467813	"AURKA Activation by TPX2";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Separation of Sister Chromatids"
Lalb_08710	6	Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176187	"Switching of origins to a post-replicative state";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress"
Lalb_13884	4	Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590	"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"NIK-->noncanonical NF-kB signaling"
Lalb_07611	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
Lalb_07432	16	Reactome: R-HSA-3134963;Reactome: R-HSA-975155;Reactome: R-HSA-6811558;Reactome: R-HSA-166058;Reactome: R-HSA-1810476;Reactome: R-HSA-5603037;Reactome: R-HSA-5603041;Reactome: R-HSA-975110;Reactome: R-HSA-209543;Reactome: R-HSA-5602498;Reactome: R-HSA-975138;Reactome: R-HSA-1236974;Reactome: R-HSA-975871;Reactome: R-HSA-5602680;Reactome: R-HSA-9020702;Reactome: R-HSA-1257604	"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"MyD88 dependent cascade initiated on endosome";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"RIP-mediated NFkB activation via ZBP1";"IRAK4 deficiency (TLR5)";"IRAK4 deficiency (TLR2/4)";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"p75NTR recruits signalling complexes";"MyD88 deficiency (TLR2/4)";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"ER-Phagosome pathway";"MyD88 cascade initiated on plasma membrane";"MyD88 deficiency (TLR5)";"Interleukin-1 signaling";"PIP3 activates AKT signaling"
Lalb_12588	13	Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-2408557	"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Selenocysteine synthesis"
Lalb_09344	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
Lalb_02297	2	Reactome: R-HSA-389661;Reactome: R-HSA-2408508	"Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
Lalb_00308	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
Lalb_04200	6	Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68867	"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA";"Assembly of the pre-replicative complex"
Lalb_11696	4	Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"RHO GTPases activate KTN1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
Lalb_09057	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
Lalb_14041	5	KEGG: 00860+4.1.1.37;Reactome: R-HSA-189451;MetaCyc: PWY-7766;MetaCyc: PWY-7159;MetaCyc: PWY-5531	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Heme b biosynthesis IV (Gram-positive bacteria)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)"
Lalb_14551	2	MetaCyc: PWY-6502;Reactome: R-HSA-2393930	"8-oxo-(d)GTP detoxification I";"Phosphate bond hydrolysis by NUDT proteins"
Lalb_07318	2	KEGG: 00563+3.5.1.89;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
Lalb_10846	8	Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
Lalb_07585	2	Reactome: R-HSA-6803157;Reactome: R-HSA-8876198	"Antimicrobial peptides";"RAB GEFs exchange GTP for GDP on RABs"
Lalb_05467	8	Reactome: R-HSA-74217;Reactome: R-HSA-5683826;KEGG: 00230+3.5.4.4;MetaCyc: PWY-6609;MetaCyc: PWY-7179-1;MetaCyc: PWY-6611;MetaCyc: PWY-7179;Reactome: R-HSA-6798695	"Purine salvage";"Surfactant metabolism";"Purine metabolism";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation I";"Neutrophil degranulation"
Lalb_04769	7	MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466	"Justicidin B biosynthesis";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis"
Lalb_13232	1	Reactome: R-HSA-156588	"Glucuronidation"
Lalb_14552	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
Lalb_00151	9	Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167162	"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape"
Lalb_02498	16	Reactome: R-HSA-8943723;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-2559585;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-426496	"Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Oncogene Induced Senescence";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Post-transcriptional silencing by small RNAs"
Lalb_05913	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
Lalb_11172	1	Reactome: R-HSA-189200	"Cellular hexose transport"
Lalb_07067	9	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
Lalb_03437	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
Lalb_08458	13	Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72706	"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit"
Lalb_04187	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
Lalb_01953	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
Lalb_13472	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
Lalb_09368	18	Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214;Reactome: R-HSA-6796648;Reactome: R-HSA-5693565;MetaCyc: PWY-7511;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-1221632;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-5693579;Reactome: R-HSA-8953750	"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins";"TP53 Regulates Transcription of DNA Repair Genes";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Protein ubiquitination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic synapsis";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"Homologous DNA Pairing and Strand Exchange";"Transcriptional Regulation by E2F6"
Lalb_09002	19	Reactome: R-HSA-975634;Reactome: R-HSA-8964041;Reactome: R-HSA-5686938;Reactome: R-HSA-8957275;Reactome: R-HSA-3000497;Reactome: R-HSA-8963888;Reactome: R-HSA-3000471;Reactome: R-HSA-8856828;Reactome: R-HSA-3000480;Reactome: R-HSA-8964026;Reactome: R-HSA-8964046;Reactome: R-HSA-8866423;Reactome: R-HSA-432142;Reactome: R-HSA-202733;Reactome: R-HSA-8963901;Reactome: R-HSA-8964038;Reactome: R-HSA-3000484;Reactome: R-HSA-381426;Reactome: R-HSA-8856825	"Retinoid metabolism and transport";"LDL remodeling";"Regulation of TLR by endogenous ligand";"Post-translational protein phosphorylation";"Scavenging by Class H Receptors";"Chylomicron assembly";"Scavenging by Class B Receptors";"Clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"Chylomicron clearance";"VLDL clearance";"VLDL assembly";"Platelet sensitization by LDL";"Cell surface interactions at the vascular wall";"Chylomicron remodeling";"LDL clearance";"Scavenging by Class F Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cargo recognition for clathrin-mediated endocytosis"
Lalb_10735	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
Lalb_14492	5	Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-75105	"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis"
Lalb_00632	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_13157	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
Lalb_11436	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
Lalb_03352	7	Reactome: R-HSA-171319;Reactome: R-HSA-201722;Reactome: R-HSA-5696394;Reactome: R-HSA-606279;Reactome: R-HSA-3214847;Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage Recognition in GG-NER";"Deposition of new CENPA-containing nucleosomes at the centromere";"HATs acetylate histones";"Ub-specific processing proteases";"UCH proteinases"
Lalb_08819	5	Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390471	"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis"
Lalb_04147	14	MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-6433	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)"
Lalb_04679	4	Reactome: R-HSA-1632852;Reactome: R-HSA-6802952;Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Macroautophagy";"Signaling by BRAF and RAF fusions";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
Lalb_11464	1	Reactome: R-HSA-6798163	"Choline catabolism"
Lalb_11442	9	Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73776	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape"
Lalb_00582	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
Lalb_10218	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
Lalb_05123	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
Lalb_08238	5	KEGG: 00270+4.2.1.109;Reactome: R-HSA-9627069;MetaCyc: PWY-4361;Reactome: R-HSA-111458;Reactome: R-HSA-1237112	"Cysteine and methionine metabolism";"Regulation of the apoptosome activity";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Formation of apoptosome";"Methionine salvage pathway"
Lalb_08071	5	Reactome: R-HSA-72165;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Minor Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
Lalb_07607	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
Lalb_00955	2	Reactome: R-HSA-8983711;Reactome: R-HSA-909733	"OAS antiviral response";"Interferon alpha/beta signaling"
Lalb_03440	2	Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
Lalb_13651	8	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2028269	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Signaling by Hippo"
Lalb_07009	1	Reactome: R-HSA-211981	"Xenobiotics"
Lalb_04925	8	Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-983231;Reactome: R-HSA-432040;Reactome: R-HSA-381676;Reactome: R-HSA-180024;Reactome: R-HSA-442720	"PKA activation";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Factors involved in megakaryocyte development and platelet production";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase"
Lalb_01449	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
Lalb_03003	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
Lalb_06359	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
Lalb_12906	5	Reactome: R-HSA-381426;Reactome: R-HSA-901042;Reactome: R-HSA-8957275;Reactome: R-HSA-879415;Reactome: R-HSA-532668	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Calnexin/calreticulin cycle";"Post-translational protein phosphorylation";"Advanced glycosylation endproduct receptor signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
Lalb_08508	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
Lalb_02092	3	Reactome: R-HSA-4724289;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.267	"Defective ALG6 causes ALG6-CDG (CDG-1c)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
Lalb_07194	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_02765	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_04258	30	Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-400253;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-69231;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-2565942;Reactome: R-HSA-2122947;Reactome: R-HSA-917937;Reactome: R-HSA-2871837;Reactome: R-HSA-1170546;Reactome: R-HSA-2894862;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-5684264;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-2644607;Reactome: R-HSA-2644606	"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"Circadian Clock";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"Cyclin D associated events in G1";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Regulation of PLK1 Activity at G2/M Transition";"NOTCH1 Intracellular Domain Regulates Transcription";"Iron uptake and transport";"FCERI mediated NF-kB activation";"Prolactin receptor signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
Lalb_06516	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
Lalb_12250	6	Reactome: R-HSA-5617472;Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-3214841;Reactome: R-HSA-3769402;Reactome: R-HSA-8951664	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines";"Deactivation of the beta-catenin transactivating complex";"Neddylation"
Lalb_11086	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
Lalb_10538	15	Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-2559586;Reactome: R-HSA-5693548;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5685939;Reactome: R-HSA-5693579;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5693616	"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Meiotic recombination";"DNA Damage/Telomere Stress Induced Senescence";"Sensing of DNA Double Strand Breaks";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through MMEJ (alt-NHEJ)";"Homologous DNA Pairing and Strand Exchange";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange"
Lalb_02120	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_11098	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
Lalb_09725	8	KEGG: 00500+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1	"Starch and sucrose metabolism";"Streptomycin biosynthesis";"Glycolysis";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism"
Lalb_14386	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
Lalb_01970	11	Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040	"PKA activation";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (s) signalling events";"G alpha (i) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins"
Lalb_04218	5	KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22	"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Glycerolipid metabolism";"Sphingolipid metabolism"
Lalb_01012	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
Lalb_05396	1	Reactome: R-HSA-156588	"Glucuronidation"
Lalb_08535	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
Lalb_01952	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
Lalb_04594	3	Reactome: R-HSA-9609523;Reactome: R-HSA-6798695;Reactome: R-HSA-1660661	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Neutrophil degranulation";"Sphingolipid de novo biosynthesis"
Lalb_11935	1	Reactome: R-HSA-189200	"Cellular hexose transport"
Lalb_10917	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
Lalb_05015	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
Lalb_10522	56	Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442	"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"Hedgehog 'on' state";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of AXIN";"Regulation of RAS by GAPs"
Lalb_05631	1	Reactome: R-HSA-189200	"Cellular hexose transport"
Lalb_07121	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
Lalb_04295	6	Reactome: R-HSA-264876;Reactome: R-HSA-6807878;Reactome: R-HSA-5620916;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-1445148	"Insulin processing";"COPI-mediated anterograde transport";"VxPx cargo-targeting to cilium";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
Lalb_04815	6	Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-429958	"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease"
Lalb_07455	5	Reactome: R-HSA-936964;Reactome: R-HSA-9013973;Reactome: R-HSA-936440;Reactome: R-HSA-933541;Reactome: R-HSA-918233	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TICAM1-dependent activation of IRF3/IRF7";"Negative regulators of DDX58/IFIH1 signaling";"TRAF6 mediated IRF7 activation";"TRAF3-dependent IRF activation pathway"
Lalb_10214	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
Lalb_07640	5	Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Amino acids regulate mTORC1";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
Lalb_03873	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
Lalb_09729	4	KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614	"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage"
Lalb_01662	1	Reactome: R-HSA-71288	"Creatine metabolism"
Lalb_12564	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
Lalb_05352	26	Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-5626467;Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-389960;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-389977;Reactome: R-HSA-6811434	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases activate IQGAPs";"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Recycling pathway of L1";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Aggrephagy";"Cilium Assembly";"Formation of tubulin folding intermediates by CCT/TriC";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Post-chaperonin tubulin folding pathway";"COPI-dependent Golgi-to-ER retrograde traffic"
Lalb_06580	1	Reactome: R-HSA-8951664	"Neddylation"
Lalb_07804	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
Lalb_10357	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
Lalb_08783	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
Lalb_07220	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
Lalb_06771	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
Lalb_06801	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
Lalb_10089	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
Lalb_09941	3	KEGG: 00350+1.13.11.5;Reactome: R-HSA-8963684;KEGG: 00643+1.13.11.5	"Tyrosine metabolism";"Tyrosine catabolism";"Styrene degradation"
Lalb_08750	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
Lalb_11179	11	Reactome: R-HSA-391160;Reactome: R-HSA-877312;Reactome: R-HSA-210990;Reactome: R-HSA-432142;Reactome: R-HSA-389948;Reactome: R-HSA-388841;Reactome: R-HSA-9008059;Reactome: R-HSA-912694;Reactome: R-HSA-909733;Reactome: R-HSA-512988;Reactome: R-HSA-114604	"Signal regulatory protein family interactions";"Regulation of IFNG signaling";"PECAM1 interactions";"Platelet sensitization by LDL";"PD-1 signaling";"Costimulation by the CD28 family";"Interleukin-37 signaling";"Regulation of IFNA signaling";"Interferon alpha/beta signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"GPVI-mediated activation cascade"
Lalb_06779	1	Reactome: R-HSA-611105	"Respiratory electron transport"
Lalb_12642	3	KEGG: 00901+2.7.1.222;Reactome: R-HSA-2672351;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Stimuli-sensing channels";"Psilocybin biosynthesis"
Lalb_04609	7	MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25;MetaCyc: PWY-2301;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-4702;Reactome: R-HSA-1855183	"D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol"
Lalb_09149	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
Lalb_08274	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
Lalb_06112	5	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing"
Lalb_12581	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_12532	1	Reactome: R-HSA-1296061	"HCN channels"
Lalb_13082	8	MetaCyc: PWY-7193;MetaCyc: PWY-6556;Reactome: R-HSA-6798695;MetaCyc: PWY-7199;KEGG: 00240+3.5.4.5;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7181;Reactome: R-HSA-73614	"Pyrimidine ribonucleosides salvage I";"Pyrimidine ribonucleosides salvage II";"Neutrophil degranulation";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine salvage"
Lalb_12889	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
Lalb_08824	4	KEGG: 00430+1.13.11.20;KEGG: 00270+1.13.11.20;MetaCyc: PWY-5331;Reactome: R-HSA-1614558	"Taurine and hypotaurine metabolism";"Cysteine and methionine metabolism";"Taurine biosynthesis I";"Degradation of cysteine and homocysteine"
Lalb_05085	1	Reactome: R-HSA-156581	"Methylation"
Lalb_05853	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
Lalb_11448	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
Lalb_02975	6	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444	"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
Lalb_02661	16	Reactome: R-HSA-5693565;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693548;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-5693571;Reactome: R-HSA-5693579;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-5685938;Reactome: R-HSA-3214847;Reactome: R-HSA-5693568	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Sensing of DNA Double Strand Breaks";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Nonhomologous End-Joining (NHEJ)";"Homologous DNA Pairing and Strand Exchange";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"HDR through Single Strand Annealing (SSA)";"HATs acetylate histones";"Resolution of D-loop Structures through Holliday Junction Intermediates"
Lalb_03703	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
Lalb_04199	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
Lalb_02978	1	MetaCyc: PWY-7511	"Protein ubiquitination"
Lalb_12095	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
Lalb_01392	4	Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-381771;Reactome: R-HSA-422085	"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin"
Lalb_06630	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
Lalb_09357	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
Lalb_04764	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
Lalb_11349	7	Reactome: R-HSA-2122948;MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862	"Activated NOTCH1 Transmits Signal to the Nucleus";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
Lalb_11787	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
Lalb_08124	1	Reactome: R-HSA-3295583	"TRP channels"
Lalb_12519	2	Reactome: R-HSA-6803205;Reactome: R-HSA-8873719	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation"
Lalb_10461	2	Reactome: R-HSA-171319;Reactome: R-HSA-3214847	"Telomere Extension By Telomerase";"HATs acetylate histones"
Lalb_08509	13	KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-4061;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6370;MetaCyc: PWY-6842;KEGG: 00980+2.5.1.18;Reactome: R-HSA-196836;Reactome: R-HSA-156590;KEGG: 00053+1.8.5.1;MetaCyc: PWY-2261;MetaCyc: PWY-7112;MetaCyc: PWY-7533	"Drug metabolism - other enzymes";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Drug metabolism - cytochrome P450";"Ascorbate recycling (cytosolic)";"Glutathione-mediated detoxification II";"Metabolism of xenobiotics by cytochrome P450";"Vitamin C (ascorbate) metabolism";"Glutathione conjugation";"Ascorbate and aldarate metabolism";"Ascorbate glutathione cycle";"4-hydroxy-2-nonenal detoxification";"Gliotoxin biosynthesis"
Lalb_00345	8	Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-6798695;Reactome: R-HSA-2565942;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Neutrophil degranulation";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes"
Lalb_04986	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
Lalb_10916	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
Lalb_12735	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
Lalb_13503	42	Reactome: R-HSA-5250924;Reactome: R-HSA-212300;Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-2299718;Reactome: R-HSA-2559580;Reactome: R-HSA-2559586;Reactome: R-HSA-606279;Reactome: R-HSA-110328;Reactome: R-HSA-3214842;Reactome: R-HSA-9610379;Reactome: R-HSA-3214858;Reactome: R-HSA-5334118;Reactome: R-HSA-3214841;Reactome: R-HSA-73772;Reactome: R-HSA-110329;Reactome: R-HSA-9609690;Reactome: R-HSA-201722;Reactome: R-HSA-5617472;Reactome: R-HSA-427413;Reactome: R-HSA-8936459;Reactome: R-HSA-4551638;Reactome: R-HSA-977225;Reactome: R-HSA-2559582;Reactome: R-HSA-73728;Reactome: R-HSA-5578749;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-427389;Reactome: R-HSA-1912408;Reactome: R-HSA-171306;Reactome: R-HSA-5693565;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-3214847;Reactome: R-HSA-1221632;Reactome: R-HSA-912446;Reactome: R-HSA-9616222;Reactome: R-HSA-5693571;Reactome: R-HSA-9018519;Reactome: R-HSA-3214815;Reactome: R-HSA-8939236	"B-WICH complex positively regulates rRNA expression";"PRC2 methylates histones and DNA";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Condensation of Prophase Chromosomes";"Oxidative Stress Induced Senescence";"DNA Damage/Telomere Stress Induced Senescence";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HDMs demethylate histones";"HCMV Late Events";"RMTs methylate histone arginines";"DNA methylation";"PKMTs methylate histone lysines";"RNA Polymerase I Promoter Escape";"Cleavage of the damaged pyrimidine";"HCMV Early Events";"Formation of the beta-catenin:TCF transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"SUMOylation of chromatin organization proteins";"Amyloid fiber formation";"Senescence-Associated Secretory Phenotype (SASP)";"RNA Polymerase I Promoter Opening";"Transcriptional regulation by small RNAs";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Pre-NOTCH Transcription and Translation";"Packaging Of Telomere Ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"HATs acetylate histones";"Meiotic synapsis";"Meiotic recombination";"Transcriptional regulation of granulopoiesis";"Nonhomologous End-Joining (NHEJ)";"Estrogen-dependent gene expression";"HDACs deacetylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
Lalb_05476	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
Lalb_03001	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
Lalb_06067	9	MetaCyc: PWY-6367;Reactome: R-HSA-416476;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-8052;MetaCyc: PWY-7039;Reactome: R-HSA-112043	"D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events"
Lalb_00248	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
Lalb_10597	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
Lalb_04268	2	Reactome: R-HSA-8939236;Reactome: R-HSA-9010553	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs"
Lalb_05289	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
Lalb_02200	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
Lalb_02998	2	Reactome: R-HSA-5683371;Reactome: R-HSA-1369007	"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters"
Lalb_14189	6	KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"Circadian Clock";"T cell receptor signaling pathway"
Lalb_10812	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
Lalb_13626	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
Lalb_01408	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_12411	5	MetaCyc: PWY-6129;Reactome: R-HSA-193048;Reactome: R-HSA-4755579;Reactome: R-HSA-446199;KEGG: 00510+1.3.1.94	"Dolichol and dolichyl phosphate biosynthesis";"Androgen biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis"
Lalb_05424	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
Lalb_04216	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
Lalb_11786	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
Lalb_05591	14	MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7725	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)"
Lalb_00676	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_02309	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
Lalb_05196	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
Lalb_05354	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
Lalb_01105	10	Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5684264;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-2565942;Reactome: R-HSA-2871837	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Regulation of PLK1 Activity at G2/M Transition";"FCERI mediated NF-kB activation"
Lalb_08574	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
Lalb_13769	9	Reactome: R-HSA-2173796;Reactome: R-HSA-1362277;Reactome: R-HSA-69231;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-6804114;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-1362300	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin D associated events in G1";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
Lalb_01830	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
Lalb_06487	13	Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339	"Viral mRNA Translation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane"
Lalb_13866	5	MetaCyc: PWY-7279;MetaCyc: PWY-3781;MetaCyc: PWY-7082;KEGG: 00190+7.1.1.8;MetaCyc: PWY-6692	"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Oxidative phosphorylation";"Fe(II) oxidation"
Lalb_10810	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
Lalb_08037	57	Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-6798695;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-9020702	"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of AXIN";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"Neutrophil degranulation";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Interleukin-1 signaling"
Lalb_00898	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
Lalb_07473	6	Reactome: R-HSA-73856;Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-77588;Reactome: R-HSA-72165;Reactome: R-HSA-111367	"RNA Polymerase II Transcription Termination";"snRNP Assembly";"mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs"
Lalb_04618	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
Lalb_08397	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_04487	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
Lalb_02579	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
Lalb_04616	4	Reactome: R-HSA-8874211;Reactome: R-HSA-1655829;Reactome: R-HSA-8963889;Reactome: R-HSA-381033	"CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Assembly of active LPL and LIPC lipase complexes";"ATF6 (ATF6-alpha) activates chaperones"
Lalb_09985	4	KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-6483;MetaCyc: PWY-7119	"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)"
Lalb_08742	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
Lalb_07639	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
Lalb_13018	13	MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-7220;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7222;KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1;KEGG: 00480+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7198	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Glutathione metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
Lalb_00454	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
Lalb_11784	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
Lalb_11577	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_06792	1	Reactome: R-HSA-189200	"Cellular hexose transport"
Lalb_10509	16	Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-176409	"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins"
Lalb_09279	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
Lalb_04403	1	Reactome: R-HSA-6783984	"Glycine degradation"
Lalb_08956	11	Reactome: R-HSA-212436;Reactome: R-HSA-383280;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-9018519;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168	"Generic Transcription Pathway";"Nuclear Receptor transcription pathway";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Estrogen-dependent gene expression";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)"
Lalb_05202	6	Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695	"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Neutrophil degranulation"
Lalb_11096	6	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10;Reactome: R-HSA-446210;MetaCyc: PWY-5514;KEGG: 00520+5.4.2.3;MetaCyc: PWY-6906	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation"
Lalb_12967	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
Lalb_06839	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
Lalb_00754	25	Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-380270;Reactome: R-HSA-437239;Reactome: R-HSA-2467813	"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Kinesins";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Recruitment of mitotic centrosome proteins and complexes";"Recycling pathway of L1";"Separation of Sister Chromatids"
Lalb_08718	5	Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-983170	"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
Lalb_01226	3	MetaCyc: PWY-5987;Reactome: R-HSA-75105;MetaCyc: PWY-5996	"Sorgoleone biosynthesis";"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis II (animals and fungi)"
Lalb_00970	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
Lalb_02653	32	Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-8851708;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167172;Reactome: R-HSA-6803529;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-167162;Reactome: R-HSA-168325;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-6807505;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-76042;Reactome: R-HSA-72163;Reactome: R-HSA-72203;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-113418	"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"Estrogen-dependent gene expression";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Signaling by FGFR2 IIIa TM";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Transcription of the HIV genome";"FGFR2 alternative splicing";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II HIV Promoter Escape";"Viral Messenger RNA Synthesis";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA polymerase II transcribes snRNA genes";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Splicing - Major Pathway";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex"
Lalb_14154	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
Lalb_01185	5	MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Lysine degradation";"Citrate cycle (TCA cycle)"
Lalb_09050	7	Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6811434	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"COPI-dependent Golgi-to-ER retrograde traffic"
Lalb_01962	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
Lalb_09673	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
Lalb_09040	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
Lalb_06492	8	MetaCyc: PWY-241;MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-7117;MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1	"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism"
Lalb_05688	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
Lalb_00719	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
Lalb_08667	9	Reactome: R-HSA-5649702;Reactome: R-HSA-110357;Reactome: R-HSA-9656256;Reactome: R-HSA-110329;Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-9657050;Reactome: R-HSA-110328;Reactome: R-HSA-9656255	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Displacement of DNA glycosylase by APEX1";"Defective OGG1 Substrate Processing";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Defective OGG1 Localization";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective OGG1 Substrate Binding"
Lalb_03285	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
Lalb_12244	4	MetaCyc: PWY-7494;MetaCyc: PWY-3722;Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1	"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism";"Glycine, serine and threonine metabolism"
Lalb_04000	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
Lalb_06832	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
Lalb_12618	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
Lalb_01877	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
Lalb_11549	1	Reactome: R-HSA-156588	"Glucuronidation"
Lalb_00980	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
Lalb_13015	3	MetaCyc: PWY-5963;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.9	"Thio-molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
Lalb_11802	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
Lalb_13730	3	KEGG: 00051+2.7.1.3;Reactome: R-HSA-5657562;Reactome: R-HSA-70350	"Fructose and mannose metabolism";"Essential fructosuria";"Fructose catabolism"
Lalb_06012	3	Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis"
Lalb_01836	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
Lalb_03858	11	Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-8854518	"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"AURKA Activation by TPX2"
Lalb_09110	8	Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-176187	"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress"
Lalb_01473	6	KEGG: 00750+2.6.1.52;MetaCyc: PWY-8010;Reactome: R-HSA-977347;KEGG: 00270+2.6.1.52;KEGG: 00680+2.6.1.52;KEGG: 00260+2.6.1.52	"Vitamin B6 metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Serine biosynthesis";"Cysteine and methionine metabolism";"Methane metabolism";"Glycine, serine and threonine metabolism"
Lalb_08146	5	Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-9615710	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy"
Lalb_09614	4	MetaCyc: PWY-7285;MetaCyc: PWY-6829;MetaCyc: PWY-7286;Reactome: R-HSA-6782315	"Methylwyosine biosynthesis";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the nucleus and cytosol"
Lalb_05947	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
Lalb_02534	5	Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-6784531	"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"tRNA processing in the nucleus"
Lalb_07259	3	KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491	"Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation"
Lalb_07300	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
Lalb_08827	8	Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-113501	"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
Lalb_03671	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
Lalb_06139	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
Lalb_03561	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
Lalb_07398	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
Lalb_09328	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
Lalb_02654	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
Lalb_11089	56	Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-1236974;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-180585	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"Degradation of AXIN";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER-Phagosome pathway";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G"
Lalb_13506	8	KEGG: 00332+2.7.2.11;KEGG: 00332+1.2.1.41;Reactome: R-HSA-8964539;KEGG: 00330+1.2.1.41;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00330+2.7.2.11;MetaCyc: PWY-6922;KEGG: 00330+1.2.1.41+2.7.2.11	"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism"
Lalb_11382	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
Lalb_06493	7	Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724	"TP53 Regulates Metabolic Genes";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription"
Lalb_10769	1	Reactome: R-HSA-1632852	"Macroautophagy"
Lalb_07059	6	Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72706	"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit"
Lalb_11248	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
Lalb_09307	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
Lalb_06976	11	Reactome: R-HSA-975634;Reactome: R-HSA-2024096;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;Reactome: R-HSA-1971475;Reactome: R-HSA-4420332;Reactome: R-HSA-202733;Reactome: R-HSA-3560783;Reactome: R-HSA-3000170;Reactome: R-HSA-3560801	"Retinoid metabolism and transport";"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Cell surface interactions at the vascular wall";"Defective B4GALT7 causes EDS, progeroid type";"Syndecan interactions";"Defective B3GAT3 causes JDSSDHD"
Lalb_00776	3	KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980	"Photosynthesis";"Oxidative phosphorylation";"ATP biosynthesis"
Lalb_00798	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
Lalb_14174	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
Lalb_06692	3	KEGG: 00600+1.14.19.17;Reactome: R-HSA-1660661;MetaCyc: PWY-5129	"Sphingolipid metabolism";"Sphingolipid de novo biosynthesis";"Sphingolipid biosynthesis (plants)"
Lalb_07250	1	MetaCyc: PWY-7511	"Protein ubiquitination"
Lalb_11099	8	MetaCyc: PWY-5668;MetaCyc: PWY-7817;Reactome: R-HSA-1483148;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;MetaCyc: PWY-5269;KEGG: 00564+3.1.3.27;KEGG: 04658+3.1.3.16	"Cardiolipin biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Synthesis of PG";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Cardiolipin biosynthesis II";"Glycerophospholipid metabolism";"Th1 and Th2 cell differentiation"
Lalb_04232	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
Lalb_08056	1	Reactome: R-HSA-611105	"Respiratory electron transport"
Lalb_01819	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
Lalb_01861	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
Lalb_09114	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
Lalb_04217	5	Reactome: R-HSA-73817;MetaCyc: PWY-6121;MetaCyc: PWY-6277;MetaCyc: PWY-6122;KEGG: 00230+6.3.5.3	"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism"
Lalb_12379	1	Reactome: R-HSA-6804760	"Regulation of TP53 Activity through Methylation"
Lalb_05996	10	MetaCyc: PWY-6362;MetaCyc: PWY-6361;MetaCyc: PWY-6369;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855191;Reactome: R-HSA-1855167;MetaCyc: PWY-6372;MetaCyc: PWY-6554;KEGG: 04070+2.7.1.158;MetaCyc: PWY-4661	"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Inositol diphosphates biosynthesis";"Inositol phosphate metabolism";"Synthesis of IPs in the nucleus";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)"
Lalb_07744	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
Lalb_13110	3	Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942	"Glutathione synthesis and recycling";"Glutathione metabolism";"5-oxo-L-proline metabolism"
Lalb_08790	4	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;MetaCyc: PWY-7221	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis"
Lalb_12388	13	KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)"
Lalb_12276	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
Lalb_10978	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_08909	9	Reactome: R-HSA-2024096;Reactome: R-HSA-3656253;Reactome: R-HSA-975634;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475;Reactome: R-HSA-2022928;Reactome: R-HSA-4420332;Reactome: R-HSA-3560783;Reactome: R-HSA-3560801	"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Retinoid metabolism and transport";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG biosynthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GAT3 causes JDSSDHD"
Lalb_01902	3	Reactome: R-HSA-71336;KEGG: 00030+1.1.1.44;KEGG: 00480+1.1.1.44	"Pentose phosphate pathway";"Pentose phosphate pathway";"Glutathione metabolism"
Lalb_04575	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
Lalb_01772	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436	"MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic"
Lalb_07323	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
Lalb_03574	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
Lalb_09774	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
Lalb_10435	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
Lalb_13231	1	Reactome: R-HSA-156588	"Glucuronidation"
Lalb_05814	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
Lalb_09513	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
Lalb_07924	5	MetaCyc: PWY-3341;MetaCyc: PWY-6344;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981	"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)"
Lalb_01076	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
Lalb_00753	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
Lalb_12934	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
Lalb_05548	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
Lalb_09574	1	Reactome: R-HSA-70171	"Glycolysis"
Lalb_11197	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
Lalb_03284	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
Lalb_13987	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
Lalb_06899	3	Reactome: R-HSA-1660662;MetaCyc: PWY-7277;KEGG: 00600+3.1.4.12	"Glycosphingolipid metabolism";"Sphingolipid biosynthesis (mammals)";"Sphingolipid metabolism"
Lalb_06324	3	Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
Lalb_13890	1	Reactome: R-HSA-8849175	"Threonine catabolism"
Lalb_13409	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
Lalb_08503	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
Lalb_12984	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
Lalb_08242	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
Lalb_05478	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
Lalb_03058	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
Lalb_01590	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
Lalb_09251	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_10211	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
Lalb_00302	6	Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430	"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"RUNX3 regulates WNT signaling"
Lalb_13311	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
Lalb_13151	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
Lalb_07632	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
Lalb_04063	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
Lalb_00166	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
Lalb_05997	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
Lalb_00517	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
Lalb_05401	2	KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
Lalb_02259	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
Lalb_07277	12	Reactome: R-HSA-2173788;Reactome: R-HSA-2467813;Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-141444	"Downregulation of TGF-beta receptor signaling";"Separation of Sister Chromatids";"Circadian Clock";"T cell receptor signaling pathway";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
Lalb_04908	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
Lalb_09399	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
Lalb_06782	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
Lalb_04535	4	Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
Lalb_05454	3	Reactome: R-HSA-8963684;KEGG: 00643+3.7.1.2;KEGG: 00350+3.7.1.2	"Tyrosine catabolism";"Styrene degradation";"Tyrosine metabolism"
Lalb_10360	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-450341;Reactome: R-HSA-2559580;Reactome: R-HSA-450321	"mTOR signaling pathway";"FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
Lalb_06326	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_04486	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
Lalb_08015	5	Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-5675221;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955	"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Negative regulation of MAPK pathway";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
Lalb_03660	5	Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-381183;Reactome: R-HSA-9614657;Reactome: R-HSA-380994	"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress"
Lalb_03610	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
Lalb_00799	20	Reactome: R-HSA-110314;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-5693616;Reactome: R-HSA-110320;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-5685938;Reactome: R-HSA-69091;Reactome: R-HSA-5656169	"Recognition of DNA damage by PCNA-containing replication complex";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion Synthesis by POLH";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"HDR through Single Strand Annealing (SSA)";"Polymerase switching";"Termination of translesion DNA synthesis"
Lalb_00990	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_09533	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
Lalb_02214	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
Lalb_03309	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
Lalb_11323	6	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
Lalb_11065	57	Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-6798695;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-195253;Reactome: R-HSA-5607761;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-9010553;Reactome: R-HSA-5362768;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-69017;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-8939902	"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neutrophil degranulation";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Degradation of beta-catenin by the destruction complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"Degradation of AXIN";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity"
Lalb_09061	9	Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-6798695;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-5674135;Reactome: R-HSA-380972;Reactome: R-HSA-165159	"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Neutrophil degranulation";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Amino acids regulate mTORC1";"MAP2K and MAPK activation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling"
Lalb_05869	3	Reactome: R-HSA-420029;Reactome: R-HSA-4608870;Reactome: R-HSA-2173791	"Tight junction interactions";"Asymmetric localization of PCP proteins";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"
Lalb_04142	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
Lalb_02648	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
Lalb_11255	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
Lalb_06992	9	Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-69205;Reactome: R-HSA-68616;Reactome: R-HSA-176187	"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"G1/S-Specific Transcription";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress"
Lalb_05032	12	MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00010+4.1.2.13;KEGG: 00051+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-5484;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00030+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-7385;MetaCyc: PWY-1861	"Glycolysis IV (plant cytosol)";"Glycolysis";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Gluconeogenesis";"Pentose phosphate pathway";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
Lalb_13395	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_11594	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
Lalb_01745	2	Reactome: R-HSA-5689880;Reactome: R-HSA-1632852	"Ub-specific processing proteases";"Macroautophagy"
Lalb_12808	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
Lalb_05398	4	KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;Reactome: R-HSA-72731;MetaCyc: PWY-4361	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Recycling of eIF2:GDP";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
Lalb_08345	3	Reactome: R-HSA-159230;Reactome: R-HSA-77588;Reactome: R-HSA-73856	"Transport of the SLBP Dependant Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination"
Lalb_02646	6	Reactome: R-HSA-72165;Reactome: R-HSA-111367;Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-77588;Reactome: R-HSA-73856	"mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination"
Lalb_11152	6	KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183;Reactome: R-HSA-1855204;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.36;Reactome: R-HSA-194840	"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Rho GTPase cycle"
Lalb_09953	7	Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-1362300	"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"Polo-like kinase mediated events";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
Lalb_03881	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
Lalb_03719	2	MetaCyc: PWY-6938;Reactome: R-HSA-430039	"NADH repair";"mRNA decay by 5' to 3' exoribonuclease"
Lalb_09569	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
Lalb_03813	13	Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-2408557	"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis"
Lalb_10942	18	Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-983189;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-6811434	"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Kinesins";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"COPI-dependent Golgi-to-ER retrograde traffic"
Lalb_06672	5	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719;Reactome: R-HSA-6798695;Reactome: R-HSA-1445148;Reactome: R-HSA-1660499	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation";"Neutrophil degranulation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Synthesis of PIPs at the plasma membrane"
Lalb_13106	4	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
Lalb_07072	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
Lalb_03994	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-1442490;Reactome: R-HSA-177929;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606	"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Collagen degradation";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
Lalb_08054	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
Lalb_06355	2	Reactome: R-HSA-936440;Reactome: R-HSA-5689896	"Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases"
Lalb_13382	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
Lalb_10487	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
Lalb_08599	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
Lalb_02634	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
Lalb_13952	7	Reactome: R-HSA-204174;Reactome: R-HSA-389661;Reactome: R-HSA-70268;Reactome: R-HSA-5362517;KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1;KEGG: 00020+1.2.4.1	"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)"
Lalb_02387	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis"
Lalb_07577	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
Lalb_07583	3	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
Lalb_08083	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
Lalb_13245	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
Lalb_05425	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
Lalb_04400	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
Lalb_04985	6	Reactome: R-HSA-5358565;Reactome: R-HSA-6796648;Reactome: R-HSA-5545483;Reactome: R-HSA-5632987;Reactome: R-HSA-5358606;Reactome: R-HSA-912446	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MLH1";"Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Meiotic recombination"
Lalb_04166	56	Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-9020702;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-174113;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768	"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Interleukin-1 signaling";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Degradation of AXIN";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
Lalb_09908	14	MetaCyc: PWY-5690;KEGG: 00650+1.3.5.1;KEGG: 00720+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-3781;Reactome: R-HSA-611105;MetaCyc: PWY-7279;MetaCyc: PWY-7254;KEGG: 00190+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-6969;MetaCyc: PWY-561	"TCA cycle II (plants and fungi)";"Butanoate metabolism";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Aerobic respiration I (cytochrome c)";"Respiratory electron transport";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle VII (acetate-producers)";"Oxidative phosphorylation";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation"
Lalb_06519	13	Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
Lalb_07984	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
Lalb_04751	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
Lalb_10059	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
Lalb_01581	5	KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-6527;MetaCyc: PWY-3821	"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"D-galactose detoxification"
Lalb_03187	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
Lalb_13857	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_01064	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
Lalb_09460	12	Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-9646399	"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy"
Lalb_12406	2	Reactome: R-HSA-8854518;Reactome: R-HSA-2160916	"AURKA Activation by TPX2";"Hyaluronan uptake and degradation"
Lalb_01650	3	KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism"
Lalb_14112	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
Lalb_09678	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
Lalb_02013	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
Lalb_04430	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
Lalb_13640	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
Lalb_10134	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
Lalb_11609	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_06575	1	Reactome: R-HSA-5617833	"Cilium Assembly"
Lalb_13267	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
Lalb_11816	1	Reactome: R-HSA-8949613	"Cristae formation"
Lalb_08980	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
Lalb_04627	1	MetaCyc: PWY-7511	"Protein ubiquitination"
Lalb_02926	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
Lalb_09088	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
Lalb_06661	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
Lalb_01898	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
Lalb_08072	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
Lalb_05933	24	Reactome: R-HSA-9634600;Reactome: R-HSA-422356;Reactome: R-HSA-8853659;KEGG: 04150+2.7.11.11;Reactome: R-HSA-442720;Reactome: R-HSA-163615;Reactome: R-HSA-5610783;Reactome: R-HSA-163358;Reactome: R-HSA-4420097;Reactome: R-HSA-983231;Reactome: R-HSA-9010642;Reactome: R-HSA-432040;Reactome: R-HSA-381676;Reactome: R-HSA-180024;Reactome: R-HSA-5610780;Reactome: R-HSA-164378;Reactome: R-HSA-5621575;Reactome: R-HSA-5687128;Reactome: R-HSA-5610787;Reactome: R-HSA-8963896;Reactome: R-HSA-163560;Reactome: R-HSA-392517;Reactome: R-HSA-111931;Reactome: R-HSA-5610785	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Regulation of insulin secretion";"RET signaling";"mTOR signaling pathway";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation";"Degradation of GLI2 by the proteasome";"PKA-mediated phosphorylation of key metabolic factors";"VEGFA-VEGFR2 Pathway";"Factors involved in megakaryocyte development and platelet production";"ROBO receptors bind AKAP5";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events";"Degradation of GLI1 by the proteasome";"PKA activation in glucagon signalling";"CD209 (DC-SIGN) signaling";"MAPK6/MAPK4 signaling";"Hedgehog 'off' state";"HDL assembly";"Triglyceride catabolism";"Rap1 signalling";"PKA-mediated phosphorylation of CREB";"GLI3 is processed to GLI3R by the proteasome"
Lalb_04254	7	Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-6798695;Reactome: R-HSA-6814122	"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
Lalb_03642	7	Reactome: R-HSA-6798695;MetaCyc: PWY-7238;Reactome: R-HSA-70221;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6724;MetaCyc: PWY-5941;MetaCyc: PWY-6737	"Neutrophil degranulation";"Sucrose biosynthesis II";"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism";"Starch degradation II";"Glycogen degradation II";"Starch degradation V"
Lalb_05324	7	Reactome: R-HSA-9033241;MetaCyc: PWY-5074;KEGG: 00650+4.1.3.4;Reactome: R-HSA-77111;KEGG: 00281+4.1.3.4;KEGG: 00280+4.1.3.4;KEGG: 00072+4.1.3.4	"Peroxisomal protein import";"Mevalonate degradation";"Butanoate metabolism";"Synthesis of Ketone Bodies";"Geraniol degradation";"Valine, leucine and isoleucine degradation";"Synthesis and degradation of ketone bodies"
Lalb_04595	1	Reactome: R-HSA-189200	"Cellular hexose transport"
Lalb_07010	1	Reactome: R-HSA-211981	"Xenobiotics"
Lalb_12292	10	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5357905;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5357956;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Regulation of TNFR1 signaling";"Thermogenesis";"Human cytomegalovirus infection";"T cell receptor signaling pathway";"Human immunodeficiency virus 1 infection";"TNFR1-induced NFkappaB signaling pathway";"mTOR signaling pathway"
Lalb_09631	6	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis"
Lalb_11666	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
Lalb_09913	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
Lalb_00609	1	Reactome: R-HSA-191859	"snRNP Assembly"
Lalb_03717	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
Lalb_07451	2	MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24	"Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis"
Lalb_10090	5	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-176407;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5687128	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"MAPK6/MAPK4 signaling"
Lalb_00915	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
Lalb_12178	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
Lalb_08092	1	Reactome: R-HSA-8951664	"Neddylation"
Lalb_00247	5	KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084	"Citrate cycle (TCA cycle)";"Lysine degradation";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA"
Lalb_02416	6	Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712	"Neutrophil degranulation";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport"
Lalb_03127	1	MetaCyc: PWY-7511	"Protein ubiquitination"
Lalb_02655	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
Lalb_00671	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
Lalb_12600	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
Lalb_02561	5	Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-75035	"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"
Lalb_13895	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
Lalb_12192	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
Lalb_06989	1	Reactome: R-HSA-8951664	"Neddylation"
Lalb_03725	15	Reactome: R-HSA-9665233;Reactome: R-HSA-9665247;Reactome: R-HSA-9665244;Reactome: R-HSA-9665250;Reactome: R-HSA-9665245;Reactome: R-HSA-1236382;Reactome: R-HSA-9665249;Reactome: R-HSA-9634285;Reactome: R-HSA-1227986;Reactome: R-HSA-9665251;Reactome: R-HSA-9664565;Reactome: R-HSA-9665246;Reactome: R-HSA-9652282;Reactome: R-HSA-8863795;Reactome: R-HSA-5637810	"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to osimertinib";"Resistance of ERBB2 KD mutants to sapitinib";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to tesevatinib";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Resistance of ERBB2 KD mutants to afatinib";"Constitutive Signaling by Overexpressed ERBB2";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to lapatinib";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to neratinib";"Drug-mediated inhibition of ERBB2 signaling";"Downregulation of ERBB2 signaling";"Constitutive Signaling by EGFRvIII"
Lalb_02469	5	Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling"
Lalb_10695	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
Lalb_03870	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
Lalb_13452	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
Lalb_08350	10	MetaCyc: PWY-8001;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-7112;MetaCyc: PWY-7559;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13	"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway";"Taurine and hypotaurine metabolism";"Glutathione metabolism"
Lalb_09616	4	Reactome: R-HSA-3000170;Reactome: R-HSA-2129379;Reactome: R-HSA-216083;Reactome: R-HSA-3000178	"Syndecan interactions";"Molecules associated with elastic fibres";"Integrin cell surface interactions";"ECM proteoglycans"
Lalb_11183	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
Lalb_14466	5	Reactome: R-HSA-201722;Reactome: R-HSA-1266695;Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509	"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Chromatin modifying enzymes"
Lalb_02864	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
Lalb_12083	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
Lalb_09601	1	Reactome: R-HSA-1632852	"Macroautophagy"
Lalb_04874	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
Lalb_08341	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
Lalb_10798	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
Lalb_05394	1	Reactome: R-HSA-156588	"Glucuronidation"
Lalb_03732	30	Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-6781823;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-5696395;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-2564830;Reactome: R-HSA-72086;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-76042;Reactome: R-HSA-167160;Reactome: R-HSA-167161;Reactome: R-HSA-73863;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-112382	"Dual incision in TC-NER";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"Cytosolic iron-sulfur cluster assembly";"mRNA Capping";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex"
Lalb_08285	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
Lalb_02912	19	Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-3214858;Reactome: R-HSA-6790901;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-8876725	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"RMTs methylate histone arginines";"rRNA modification in the nucleus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Protein methylation"
Lalb_10836	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_02327	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
Lalb_12308	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
Lalb_13170	18	MetaCyc: PWY-7783;MetaCyc: PWY-7409;Reactome: R-HSA-1482801;MetaCyc: PWY-6803;Reactome: R-HSA-1482925;MetaCyc: PWY-8051;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4	"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PS";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PG";"Anandamide biosynthesis I";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Synthesis of PA";"Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism"
Lalb_08952	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
Lalb_02173	1	MetaCyc: PWY-7511	"Protein ubiquitination"
Lalb_04553	14	MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7035	"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis"
Lalb_05949	1	Reactome: R-HSA-3295583	"TRP channels"
Lalb_11804	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import"
Lalb_03124	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
Lalb_07316	7	Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284	"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
Lalb_04967	2	Reactome: R-HSA-9033500;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import"
Lalb_08344	5	Reactome: R-HSA-1834949;Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695	"Cytosolic sensors of pathogen-associated DNA";"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation"
Lalb_10651	1	Reactome: R-HSA-176974	"Unwinding of DNA"
Lalb_02242	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
Lalb_07916	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_03375	4	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
Lalb_12711	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
Lalb_08902	2	KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608	"Aminoacyl-tRNA biosynthesis";"Platelet degranulation"
Lalb_02776	6	Reactome: R-HSA-3322077;MetaCyc: PWY-622;MetaCyc: PWY-5067;Reactome: R-HSA-3878781;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18	"Glycogen synthesis";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen storage disease type IV (GBE1)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism"
Lalb_13623	2	Reactome: R-HSA-3108214;Reactome: R-HSA-5685938	"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)"
Lalb_00575	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
Lalb_13915	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
Lalb_08053	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1660499;Reactome: R-HSA-111465	"T cell receptor signaling pathway";"Synthesis of PIPs at the plasma membrane";"Apoptotic cleavage of cellular proteins"
Lalb_06553	1	Reactome: R-HSA-8951664	"Neddylation"
Lalb_09543	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
Lalb_07224	3	Reactome: R-HSA-6783310;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Fanconi Anemia Pathway";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_00975	13	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
Lalb_03305	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_00610	4	Reactome: R-HSA-6798695;Reactome: R-HSA-446203;Reactome: R-HSA-1799339;Reactome: R-HSA-879415	"Neutrophil degranulation";"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane";"Advanced glycosylation endproduct receptor signaling"
Lalb_05163	19	Reactome: R-HSA-8964026;Reactome: R-HSA-8964046;Reactome: R-HSA-8866423;Reactome: R-HSA-202733;Reactome: R-HSA-432142;Reactome: R-HSA-8856825;Reactome: R-HSA-381426;Reactome: R-HSA-3000484;Reactome: R-HSA-8963901;Reactome: R-HSA-8964038;Reactome: R-HSA-3000497;Reactome: R-HSA-8957275;Reactome: R-HSA-5686938;Reactome: R-HSA-8964041;Reactome: R-HSA-975634;Reactome: R-HSA-3000471;Reactome: R-HSA-8856828;Reactome: R-HSA-3000480;Reactome: R-HSA-8963888	"Chylomicron clearance";"VLDL clearance";"VLDL assembly";"Cell surface interactions at the vascular wall";"Platelet sensitization by LDL";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class F Receptors";"Chylomicron remodeling";"LDL clearance";"Scavenging by Class H Receptors";"Post-translational protein phosphorylation";"Regulation of TLR by endogenous ligand";"LDL remodeling";"Retinoid metabolism and transport";"Scavenging by Class B Receptors";"Clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"Chylomicron assembly"
Lalb_14469	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
Lalb_12854	2	Reactome: R-HSA-1221632;Reactome: R-HSA-5601884	"Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis"
Lalb_08720	11	MetaCyc: PWY-6608;MetaCyc: PWY-6606;MetaCyc: PWY-5497;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6596;MetaCyc: PWY-5695;MetaCyc: PWY-6999;Reactome: R-HSA-8851680;MetaCyc: PWY-6607;Reactome: R-HSA-74259;MetaCyc: PWY-6538	"Guanosine nucleotides degradation III";"Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Purine metabolism";"Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Theophylline degradation";"Butyrophilin (BTN) family interactions";"Guanosine nucleotides degradation I";"Purine catabolism";"Caffeine degradation III (bacteria, via demethylation)"
Lalb_00797	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
Lalb_09055	3	Reactome: R-HSA-6782315;MetaCyc: PWY-8106;MetaCyc: PWY-6700	"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)"
Lalb_07242	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_10325	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
Lalb_10937	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
Lalb_07493	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
Lalb_05099	33	Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-141444;Reactome: R-HSA-3108214;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-2467813;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-2500257;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-4570464	"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA damage response and repair proteins";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"Separation of Sister Chromatids";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins"
Lalb_09837	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
Lalb_06177	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
Lalb_05393	1	Reactome: R-HSA-156588	"Glucuronidation"
Lalb_10242	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
Lalb_12587	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_02238	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
Lalb_05938	1	Reactome: R-HSA-264876	"Insulin processing"
Lalb_01928	5	MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14	"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism"
Lalb_08979	1	Reactome: R-HSA-977347	"Serine biosynthesis"
Lalb_06466	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
Lalb_10199	7	KEGG: 00564+2.7.8.11;MetaCyc: PWY-6352;Reactome: R-HSA-1483226;KEGG: 04070+2.7.8.11;MetaCyc: PWY-7625;MetaCyc: PWY-6351;KEGG: 00562+2.7.8.11	"Glycerophospholipid metabolism";"3-phosphoinositide biosynthesis";"Synthesis of PI";"Phosphatidylinositol signaling system";"Phosphatidylinositol biosynthesis II (eukaryotes)";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism"
Lalb_12003	7	Reactome: R-HSA-5658034;Reactome: R-HSA-5635838;Reactome: R-HSA-5362798;Reactome: R-HSA-373080;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5632681	"HHAT G278V abrogates palmitoylation of Hh-Np";"Activation of SMO";"Release of Hh-Np from the secreting cell";"Class B/2 (Secretin family receptors)";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Ligand-receptor interactions"
Lalb_01609	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs"
Lalb_14042	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
Lalb_12269	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
Lalb_07720	3	Reactome: R-HSA-2206282;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.50	"MPS IIIB - Sanfilippo syndrome B";"HS-GAG degradation";"Glycosaminoglycan degradation"
Lalb_11477	1	Reactome: R-HSA-6798163	"Choline catabolism"
Lalb_13282	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
Lalb_13156	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
Lalb_00736	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825	"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis"
Lalb_08160	4	Reactome: R-HSA-73817;KEGG: 00230+6.3.4.4;KEGG: 00250+6.3.4.4;MetaCyc: PWY-7219	"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis"
Lalb_08984	11	MetaCyc: PWY-7102;Reactome: R-HSA-191273;MetaCyc: PWY-7560;MetaCyc: PWY-5123;MetaCyc: PWY-6383;MetaCyc: PWY-6174;KEGG: 00900+5.3.3.2;MetaCyc: PWY-6859;MetaCyc: PWY-7524;MetaCyc: PWY-7391;MetaCyc: PWY-922	"Bisabolene biosynthesis (engineered)";"Cholesterol biosynthesis";"Methylerythritol phosphate pathway II";"Trans, trans-farnesyl diphosphate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"All-trans-farnesol biosynthesis";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I"
Lalb_06541	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_06123	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
Lalb_00150	57	Reactome: R-HSA-5607761;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-6798695;Reactome: R-HSA-174113;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-69481	"Dectin-1 mediated noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neutrophil degranulation";"SCF-beta-TrCP mediated degradation of Emi1";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Interleukin-1 signaling";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"Regulation of RAS by GAPs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints"
Lalb_08121	4	Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
Lalb_09923	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
Lalb_04588	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
Lalb_10640	6	Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
Lalb_08738	2	KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9	"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate"
Lalb_06543	1	Reactome: R-HSA-8964038	"LDL clearance"
Lalb_13473	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
Lalb_03492	3	Reactome: R-HSA-9609736;Reactome: R-HSA-212676;Reactome: R-HSA-6794361	"Assembly and cell surface presentation of NMDA receptors";"Dopamine Neurotransmitter Release Cycle";"Neurexins and neuroligins"
Lalb_04965	2	Reactome: R-HSA-1799339;Reactome: R-HSA-446203	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation"
Lalb_11332	5	Reactome: R-HSA-168638;Reactome: R-HSA-376172;KEGG: 04150+2.7.11.24;Reactome: R-HSA-4420097;Reactome: R-HSA-171007	"NOD1/2 Signaling Pathway";"DSCAM interactions";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"p38MAPK events"
Lalb_12038	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
Lalb_04781	9	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"tRNA modification in the nucleus and cytosol";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
Lalb_10297	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
Lalb_13135	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
Lalb_06793	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
Lalb_04240	7	MetaCyc: PWY-7886;MetaCyc: PWY-7818;MetaCyc: PWY-3385;MetaCyc: PWY-7782;Reactome: R-HSA-1483191;KEGG: 00564+2.7.1.32+2.7.1.82;Reactome: R-HSA-1483213	"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Choline biosynthesis I";"Plasmalogen biosynthesis";"Synthesis of PC";"Glycerophospholipid metabolism";"Synthesis of PE"
Lalb_08338	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
Lalb_00748	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
Lalb_07094	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
Lalb_03624	5	Reactome: R-HSA-1169408;Reactome: R-HSA-6811555;Reactome: R-HSA-6804756;Reactome: R-HSA-5668599;Reactome: R-HSA-936440	"ISG15 antiviral mechanism";"PI5P Regulates TP53 Acetylation";"Regulation of TP53 Activity through Phosphorylation";"RHO GTPases Activate NADPH Oxidases";"Negative regulators of DDX58/IFIH1 signaling"
Lalb_05630	1	Reactome: R-HSA-189200	"Cellular hexose transport"
Lalb_13682	1	Reactome: R-HSA-156588	"Glucuronidation"
Lalb_04156	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
Lalb_05979	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
Lalb_10819	5	MetaCyc: PWY-7919;Reactome: R-HSA-532668;MetaCyc: PWY-7918;KEGG: 00510+3.2.1.106;Reactome: R-HSA-4793954	"Protein N-glycosylation processing phase (plants and animals)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein N-glycosylation processing phase (yeast)";"N-Glycan biosynthesis";"Defective MOGS causes MOGS-CDG (CDG-2b)"
Lalb_04945	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
Lalb_01918	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
Lalb_11999	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
Lalb_10300	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_10563	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_05963	3	Reactome: R-HSA-381426;Reactome: R-HSA-5362798;Reactome: R-HSA-8957275	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Release of Hh-Np from the secreting cell";"Post-translational protein phosphorylation"
Lalb_00559	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
Lalb_14559	27	Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-165054;Reactome: R-HSA-159227	"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"snRNP Assembly";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA"
Lalb_11677	9	MetaCyc: PWY-5744;MetaCyc: PWY-7117;MetaCyc: PWY-5743;MetaCyc: PWY-7115;Reactome: R-HSA-1475029;MetaCyc: PWY-241;MetaCyc: PWY-5789;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1	"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism"
Lalb_08941	4	Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216	"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Collagen chain trimerization"
Lalb_13115	4	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
Lalb_12670	1	Reactome: R-HSA-156588	"Glucuronidation"
Lalb_09250	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_06095	14	MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-6433	"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)"
Lalb_09359	17	Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339	"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane"
Lalb_09010	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
Lalb_03638	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
Lalb_06178	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
Lalb_01655	5	Reactome: R-HSA-389661;Reactome: R-HSA-3214858;Reactome: R-HSA-191859;Reactome: R-HSA-6783984;Reactome: R-HSA-6804760	"Glyoxylate metabolism and glycine degradation";"RMTs methylate histone arginines";"snRNP Assembly";"Glycine degradation";"Regulation of TP53 Activity through Methylation"
Lalb_12924	11	Reactome: R-HSA-8862803;Reactome: R-HSA-9018519;Reactome: R-HSA-5617472;Reactome: R-HSA-8943724;Reactome: R-HSA-6796648;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-2871796;Reactome: R-HSA-2559582;Reactome: R-HSA-450341;Reactome: R-HSA-5687128	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Estrogen-dependent gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of PTEN gene transcription";"TP53 Regulates Transcription of DNA Repair Genes";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"FCERI mediated MAPK activation";"Senescence-Associated Secretory Phenotype (SASP)";"Activation of the AP-1 family of transcription factors";"MAPK6/MAPK4 signaling"
Lalb_05063	4	Reactome: R-HSA-6794361;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825	"Neurexins and neuroligins";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis"
Lalb_05792	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
Lalb_01359	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
Lalb_07006	1	Reactome: R-HSA-211981	"Xenobiotics"
Lalb_03084	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
Lalb_01856	13	Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
Lalb_14115	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
Lalb_10556	5	Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-937072;Reactome: R-HSA-936964	"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
Lalb_05142	5	MetaCyc: PWY-7511;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-381038;Reactome: R-HSA-901032	"Protein ubiquitination";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"XBP1(S) activates chaperone genes";"ER Quality Control Compartment (ERQC)"
Lalb_04706	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
Lalb_01930	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
Lalb_08826	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
Lalb_00159	24	Reactome: R-HSA-4086398;Reactome: R-HSA-418217;Reactome: R-HSA-418592;Reactome: R-HSA-418555;Reactome: R-HSA-400042;Reactome: R-HSA-202040;Reactome: R-HSA-8964616;Reactome: R-HSA-392851;Reactome: R-HSA-456926;Reactome: R-HSA-418594;Reactome: R-HSA-500657;Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-420092;Reactome: R-HSA-428930;Reactome: R-HSA-9009391;Reactome: R-HSA-416476;Reactome: R-HSA-392451;Reactome: R-HSA-416482;Reactome: R-HSA-6814122;Reactome: R-HSA-8964315;Reactome: R-HSA-392170	"Ca2+ pathway";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 1";"G alpha (s) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"G-protein activation";"G beta:gamma signalling through CDC42";"Prostacyclin signalling through prostacyclin receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (i) signalling events";"Presynaptic function of Kainate receptors";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"Glucagon-type ligand receptors";"Thromboxane signalling through TP receptor";"Extra-nuclear estrogen signaling";"G alpha (q) signalling events";"G beta:gamma signalling through PI3Kgamma";"G alpha (12/13) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through BTK";"ADP signalling through P2Y purinoceptor 12"
Lalb_04234	4	KEGG: 00900+2.5.1.87;MetaCyc: PWY-6129;Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Terpenoid backbone biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
Lalb_06728	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
Lalb_09253	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_00621	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
Lalb_06241	5	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-3214815;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
Lalb_05100	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_01301	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
Lalb_13462	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
Lalb_07249	5	MetaCyc: PWY-6892;KEGG: 00730+2.2.1.7;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6891;MetaCyc: PWY-7560	"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiamine metabolism";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis II (aerobic bacteria)";"Methylerythritol phosphate pathway II"
Lalb_01495	13	Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-2408557	"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis"
Lalb_12191	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
Lalb_08342	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
Lalb_11489	3	Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-429947	"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Deadenylation of mRNA"
Lalb_02359	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
Lalb_07128	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
Lalb_03365	2	Reactome: R-HSA-2514853;Reactome: R-HSA-2299718	"Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes"
Lalb_07635	1	Reactome: R-HSA-114608	"Platelet degranulation"
Lalb_09726	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
Lalb_04613	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
Lalb_11553	8	Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-176187	"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress"
Lalb_00486	17	Reactome: R-HSA-176412;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-176407;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-176409;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-174048;Reactome: R-HSA-174154	"Phosphorylation of the APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin"
Lalb_11079	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
Lalb_03296	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
Lalb_01758	52	Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-8939902;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-450408	"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Regulation of PTEN stability and activity";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX2 expression and activity";"Regulation of RAS by GAPs";"Degradation of AXIN";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA"
Lalb_06497	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
Lalb_11331	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
Lalb_09580	2	MetaCyc: PWY-7802;MetaCyc: PWY-7799	"N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)"
Lalb_10427	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
Lalb_04521	12	KEGG: 04714+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416476;KEGG: 05163+2.7.11.1;Reactome: R-HSA-418885;Reactome: R-HSA-416482	"Thermogenesis";"Rho GTPase cycle";"Human papillomavirus infection";"NRAGE signals death through JNK";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"G alpha (q) signalling events";"Human cytomegalovirus infection";"DCC mediated attractive signaling";"G alpha (12/13) signalling events"
Lalb_06463	7	KEGG: 00270+6.3.2.2;Reactome: R-HSA-5578999;MetaCyc: PWY-7255;MetaCyc: PWY-8043;Reactome: R-HSA-174403;MetaCyc: PWY-6840;KEGG: 00480+6.3.2.2	"Cysteine and methionine metabolism";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Ergothioneine biosynthesis I (bacteria)";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Homoglutathione biosynthesis";"Glutathione metabolism"
Lalb_05546	6	Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-975957	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
Lalb_03123	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
Lalb_12740	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
Lalb_05803	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
Lalb_12354	2	Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77	"Methionine salvage pathway";"Cysteine and methionine metabolism"
Lalb_02863	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
Lalb_02917	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
Lalb_13079	1	Reactome: R-HSA-6806664	"Metabolism of vitamin K"
Lalb_10797	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
Lalb_03609	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
Lalb_00093	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
Lalb_01213	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
Lalb_08379	5	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-159231	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript"
Lalb_12783	2	Reactome: R-HSA-2564830;Reactome: R-HSA-5693554	"Cytosolic iron-sulfur cluster assembly";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
Lalb_01127	1	Reactome: R-HSA-189451	"Heme biosynthesis"
Lalb_01143	9	Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73776	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape"
Lalb_01075	2	MetaCyc: PWY-7511;Reactome: R-HSA-6783310	"Protein ubiquitination";"Fanconi Anemia Pathway"
Lalb_06176	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
Lalb_10996	1	Reactome: R-HSA-1632852	"Macroautophagy"
Lalb_04215	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
Lalb_01227	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
Lalb_06390	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_10233	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
Lalb_01569	6	Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616	"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange"
Lalb_05413	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_00757	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
Lalb_09832	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
Lalb_12510	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
Lalb_03188	4	KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism"
Lalb_10694	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
Lalb_12621	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
Lalb_00414	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
Lalb_14349	5	Reactome: R-HSA-9029558;Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;Reactome: R-HSA-75105	"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis"
Lalb_06345	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
Lalb_01479	13	MetaCyc: PWY-5538;KEGG: 00020+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-6969;MetaCyc: PWY-7384;KEGG: 00720+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-6728;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5537	"Pyruvate fermentation to acetate VI";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate V"
Lalb_12073	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
Lalb_02602	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
Lalb_05468	7	Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-4086400;Reactome: R-HSA-5368598;Reactome: R-HSA-4641258;Reactome: R-HSA-201681;Reactome: R-HSA-201688	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"PCP/CE pathway";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"Degradation of DVL";"TCF dependent signaling in response to WNT";"WNT mediated activation of DVL"
Lalb_10866	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_09863	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
Lalb_06251	1	Reactome: R-HSA-8949613	"Cristae formation"
Lalb_06903	4	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379726;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation"
Lalb_12744	6	Reactome: R-HSA-6781823;Reactome: R-HSA-6798695;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135	"Formation of TC-NER Pre-Incision Complex";"Neutrophil degranulation";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER"
Lalb_06244	4	KEGG: 00670+1.5.1.6;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;Reactome: R-HSA-196757	"One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Metabolism of folate and pterines"
Lalb_05485	26	Reactome: R-HSA-5621575;Reactome: R-HSA-933541;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-8866907;Reactome: R-HSA-381340;Reactome: R-HSA-3371568;Reactome: R-HSA-918233;Reactome: R-HSA-400253;Reactome: R-HSA-9013508;Reactome: R-HSA-9614657;Reactome: R-HSA-1368082;Reactome: R-HSA-2644606;Reactome: R-HSA-9013695;Reactome: R-HSA-1989781;Reactome: R-HSA-3134973;Reactome: R-HSA-1234158;Reactome: R-HSA-9617629;Reactome: R-HSA-3214847;Reactome: R-HSA-2894862;Reactome: R-HSA-3899300;Reactome: R-HSA-210744;Reactome: R-HSA-201722;Reactome: R-HSA-5617472;Reactome: R-HSA-9018519;Reactome: R-HSA-2122947	"CD209 (DC-SIGN) signaling";"TRAF6 mediated IRF7 activation";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"Activation of the TFAP2 (AP-2) family of transcription factors";"Transcriptional regulation of white adipocyte differentiation";"Attenuation phase";"TRAF3-dependent IRF activation pathway";"Circadian Clock";"NOTCH3 Intracellular Domain Regulates Transcription";"FOXO-mediated transcription of cell death genes";"RORA activates gene expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression by Hypoxia-inducible Factor";"Regulation of FOXO transcriptional activity by acetylation";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SUMOylation of transcription cofactors";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Formation of the beta-catenin:TCF transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Estrogen-dependent gene expression";"NOTCH1 Intracellular Domain Regulates Transcription"
Lalb_11607	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_11679	1	Reactome: R-HSA-189200	"Cellular hexose transport"
Lalb_09558	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_14048	10	Reactome: R-HSA-111457;Reactome: R-HSA-2151201;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-111459;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-3299685;Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"Release of apoptotic factors from the mitochondria";"Transcriptional activation of mitochondrial biogenesis";"Formation of apoptosome";"Regulation of the apoptosome activity";"Activation of caspases through apoptosome-mediated cleavage";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Detoxification of Reactive Oxygen Species";"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
Lalb_04894	31	MetaCyc: PWY-7746;Reactome: R-HSA-163765;MetaCyc: PWY-6799;MetaCyc: PWY-7388;MetaCyc: PWYG-321;MetaCyc: PWY-8012;Reactome: R-HSA-75105;MetaCyc: PWY-7858;MetaCyc: PWY-5142;MetaCyc: PWY-6519;Reactome: R-HSA-9029558;MetaCyc: PWY-5994;MetaCyc: PWY-5366;MetaCyc: PWY-8049;MetaCyc: PWY-5367;MetaCyc: PWY-6113;MetaCyc: PWY-5973;MetaCyc: PWY-7723;MetaCyc: PWY-7664;MetaCyc: PWY-5971;MetaCyc: PWY-6282;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5966-1;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-199220;MetaCyc: PWY-5989;MetaCyc: PWY-8047;MetaCyc: PWY-4381;MetaCyc: PWY-5147;Reactome: R-HSA-2426168;MetaCyc: PWY-7663	"Mycobacterial sulfolipid biosynthesis";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (plant mitochondria)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"";"Mupirocin biosynthesis";"Fatty acyl-CoA biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Acyl-[acyl-carrier protein] thioesterase pathway";"8-amino-7-oxononanoate biosynthesis I";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Pederin biosynthesis";"Petroselinate biosynthesis";"Superpathway of mycolate biosynthesis";"Cis-vaccenate biosynthesis";"Bacterial bioluminescence";"Oleate biosynthesis IV (anaerobic)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Biotin metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Stearate biosynthesis II (bacteria and plants)";"Bryostatin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Oleate biosynthesis I (plants)";"Activation of gene expression by SREBF (SREBP)";"Gondoate biosynthesis (anaerobic)"
Lalb_05918	8	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6791226	"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_13807	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
Lalb_08702	26	Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-389960;Reactome: R-HSA-9646399;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-437239;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Cilium Assembly";"Formation of tubulin folding intermediates by CCT/TriC";"Aggrephagy";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Recycling pathway of L1";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
Lalb_13396	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
Lalb_04642	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
Lalb_01369	24	KEGG: 04926+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-9634635;Reactome: R-HSA-2730905;Reactome: R-HSA-2871837;KEGG: 04150+2.7.11.1;Reactome: R-HSA-114604;KEGG: 04151+2.7.11.1;Reactome: R-HSA-389357;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-202424;Reactome: R-HSA-5218920;KEGG: 04714+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-6804757;Reactome: R-HSA-5625740;Reactome: R-HSA-5607764;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-354192;Reactome: R-HSA-444257	"Relaxin signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"G beta:gamma signalling through PI3Kgamma";"Estrogen-stimulated signaling through PRKCZ";"Role of LAT2/NTAL/LAB on calcium mobilization";"FCERI mediated NF-kB activation";"mTOR signaling pathway";"GPVI-mediated activation cascade";"PI3K-Akt signaling pathway";"CD28 dependent PI3K/Akt signaling";"Human papillomavirus infection";"PIP3 activates AKT signaling";"Downstream TCR signaling";"VEGFR2 mediated vascular permeability";"Thermogenesis";"Activation of AKT2";"Regulation of TP53 Degradation";"RHO GTPases activate PKNs";"CLEC7A (Dectin-1) signaling";"Human immunodeficiency virus 1 infection";"VEGFR2 mediated cell proliferation";"Integrin signaling";"RSK activation"
Lalb_11621	1	Reactome: R-HSA-6804759	"Regulation of TP53 Activity through Association with Co-factors"
Lalb_05242	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
Lalb_00509	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
Lalb_08406	4	KEGG: 00510+2.4.1.259+2.4.1.261;KEGG: 00513+2.4.1.261;Reactome: R-HSA-446193;Reactome: R-HSA-4720454	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG9 causes ALG9-CDG (CDG-1l)"
Lalb_13090	3	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
Lalb_07202	2	KEGG: 00062+3.1.2.22;Reactome: R-HSA-75105	"Fatty acid elongation";"Fatty acyl-CoA biosynthesis"
Lalb_11646	2	Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
Lalb_13487	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
Lalb_11650	5	MetaCyc: PWY-6902;MetaCyc: PWY-6855;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)"
Lalb_09025	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
Lalb_09124	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
Lalb_04922	3	Reactome: R-HSA-6798695;Reactome: R-HSA-264870;Reactome: R-HSA-6794361	"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins";"Neurexins and neuroligins"
Lalb_06153	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
Lalb_12855	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
Lalb_06144	5	KEGG: 00900+2.7.4.2;Reactome: R-HSA-191273;MetaCyc: PWY-922;MetaCyc: PWY-7391;Reactome: R-HSA-2426168	"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)"
Lalb_14554	1	Reactome: R-HSA-71288	"Creatine metabolism"
Lalb_00545	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_06795	1	Reactome: R-HSA-8876725	"Protein methylation"
Lalb_06597	1	Reactome: R-HSA-203615	"eNOS activation"
Lalb_02650	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
Lalb_00121	6	Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-6791226	"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_01886	11	MetaCyc: PWY-7184;KEGG: 00240+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7206	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Pantothenate and CoA biosynthesis";"Tunicamycin biosynthesis";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation"
Lalb_10581	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_06132	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
Lalb_04749	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
Lalb_00536	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
Lalb_13961	3	MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695	"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Neutrophil degranulation"
Lalb_11258	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
Lalb_06540	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
Lalb_00584	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
Lalb_07229	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
Lalb_09261	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578998	"Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)"
Lalb_13644	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
Lalb_02127	6	Reactome: R-HSA-201722;Reactome: R-HSA-5626467;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-3769402;Reactome: R-HSA-2173796	"Formation of the beta-catenin:TCF transactivating complex";"RHO GTPases activate IQGAPs";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Deactivation of the beta-catenin transactivating complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"
Lalb_08504	14	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167287	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery"
Lalb_07681	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
Lalb_11068	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
Lalb_01563	1	Reactome: R-HSA-5635838	"Activation of SMO"
Lalb_11380	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
Lalb_05677	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
Lalb_06106	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
Lalb_07554	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
Lalb_09388	18	MetaCyc: PWY-6803;Reactome: R-HSA-1482801;Reactome: R-HSA-1482925;MetaCyc: PWY-7409;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;MetaCyc: PWY-8051;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4	"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PS";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Anandamide biosynthesis I";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Synthesis of PA";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism"
Lalb_12709	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_01684	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
Lalb_11163	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
Lalb_01103	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
Lalb_00303	13	Reactome: R-HSA-5358346;Reactome: R-HSA-201722;Reactome: R-HSA-5632681;Reactome: R-HSA-3769402;Reactome: R-HSA-5658034;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-5632684;Reactome: R-HSA-8951430;Reactome: R-HSA-5635838;Reactome: R-HSA-4086398;Reactome: R-HSA-373080;Reactome: R-HSA-5362798	"Hedgehog ligand biogenesis";"Formation of the beta-catenin:TCF transactivating complex";"Ligand-receptor interactions";"Deactivation of the beta-catenin transactivating complex";"HHAT G278V abrogates palmitoylation of Hh-Np";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"Hedgehog 'on' state";"RUNX3 regulates WNT signaling";"Activation of SMO";"Ca2+ pathway";"Class B/2 (Secretin family receptors)";"Release of Hh-Np from the secreting cell"
Lalb_05678	4	Reactome: R-HSA-964975;MetaCyc: PWY-7204;MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5	"Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism"
Lalb_00347	3	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.5;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
Lalb_13041	20	Reactome: R-HSA-5656121;Reactome: R-HSA-5693616;Reactome: R-HSA-110320;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-110314;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135	"Translesion synthesis by POLI";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion Synthesis by POLH";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Recognition of DNA damage by PCNA-containing replication complex";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Dual incision in TC-NER"
Lalb_12765	24	Reactome: R-HSA-400042;Reactome: R-HSA-418555;Reactome: R-HSA-418592;Reactome: R-HSA-418217;Reactome: R-HSA-4086398;Reactome: R-HSA-432040;Reactome: R-HSA-381676;Reactome: R-HSA-500657;Reactome: R-HSA-418594;Reactome: R-HSA-392851;Reactome: R-HSA-456926;Reactome: R-HSA-8964616;Reactome: R-HSA-202040;Reactome: R-HSA-9009391;Reactome: R-HSA-428930;Reactome: R-HSA-420092;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-392170;Reactome: R-HSA-8964315;Reactome: R-HSA-6814122;Reactome: R-HSA-416482;Reactome: R-HSA-392451;Reactome: R-HSA-416476	"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (s) signalling events";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PLC beta";"Ca2+ pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Presynaptic function of Kainate receptors";"G alpha (i) signalling events";"Prostacyclin signalling through prostacyclin receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through CDC42";"G-protein activation";"Extra-nuclear estrogen signaling";"Thromboxane signalling through TP receptor";"Glucagon-type ligand receptors";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through BTK";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (12/13) signalling events";"G beta:gamma signalling through PI3Kgamma";"G alpha (q) signalling events"
Lalb_10712	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
Lalb_11475	1	Reactome: R-HSA-6798163	"Choline catabolism"
Lalb_06598	15	Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-2559580;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-2559585;Reactome: R-HSA-8936459;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897	"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"Oxidative Stress Induced Senescence";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Oncogene Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes"
Lalb_02386	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
Lalb_01264	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
Lalb_11478	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_05699	5	Reactome: R-HSA-68827;Reactome: R-HSA-69205;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962	"CDT1 association with the CDC6:ORC:origin complex";"G1/S-Specific Transcription";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex"
Lalb_07692	17	MetaCyc: PWY-7176;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7197;MetaCyc: PWY-7187;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7210;MetaCyc: PWY-7221;MetaCyc: PWY-7205;MetaCyc: PWY-7220;MetaCyc: PWY-7184;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-6545	"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine ribonucleotides de novo biosynthesis";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
Lalb_11569	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
Lalb_02937	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
Lalb_03697	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
Lalb_05103	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
Lalb_09612	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
Lalb_13240	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
Lalb_00222	7	Reactome: R-HSA-5696394;Reactome: R-HSA-5696400;Reactome: R-HSA-110362;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-2173795;Reactome: R-HSA-5685939	"DNA Damage Recognition in GG-NER";"Dual Incision in GG-NER";"POLB-Dependent Long Patch Base Excision Repair";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"HDR through MMEJ (alt-NHEJ)"
Lalb_07700	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
Lalb_13869	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
Lalb_13171	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
Lalb_13748	12	Reactome: R-HSA-2132295;Reactome: R-HSA-380284;Reactome: R-HSA-381038;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-6807878;Reactome: R-HSA-2565942	"MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome";"XBP1(S) activates chaperone genes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition"
Lalb_00544	2	Reactome: R-HSA-6790901;Reactome: R-HSA-8869496	"rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
Lalb_03006	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
Lalb_11687	3	Reactome: R-HSA-6787450;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470	"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion"
Lalb_11501	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
Lalb_08684	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
Lalb_02295	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
Lalb_09497	3	Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-948021	"COPII-mediated vesicle transport";"Cargo concentration in the ER";"Transport to the Golgi and subsequent modification"
Lalb_02545	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_13497	42	Reactome: R-HSA-110329;Reactome: R-HSA-73772;Reactome: R-HSA-3214841;Reactome: R-HSA-5334118;Reactome: R-HSA-977225;Reactome: R-HSA-4551638;Reactome: R-HSA-8936459;Reactome: R-HSA-5617472;Reactome: R-HSA-427413;Reactome: R-HSA-201722;Reactome: R-HSA-9609690;Reactome: R-HSA-2559586;Reactome: R-HSA-2299718;Reactome: R-HSA-110330;Reactome: R-HSA-2559580;Reactome: R-HSA-110331;Reactome: R-HSA-212300;Reactome: R-HSA-5250924;Reactome: R-HSA-3214858;Reactome: R-HSA-9610379;Reactome: R-HSA-3214842;Reactome: R-HSA-110328;Reactome: R-HSA-606279;Reactome: R-HSA-9616222;Reactome: R-HSA-912446;Reactome: R-HSA-1221632;Reactome: R-HSA-3214847;Reactome: R-HSA-8939236;Reactome: R-HSA-3214815;Reactome: R-HSA-9018519;Reactome: R-HSA-5693571;Reactome: R-HSA-1912408;Reactome: R-HSA-427389;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-2559582;Reactome: R-HSA-5578749;Reactome: R-HSA-73728;Reactome: R-HSA-427359;Reactome: R-HSA-5625886;Reactome: R-HSA-5693565;Reactome: R-HSA-171306	"Cleavage of the damaged pyrimidine";"RNA Polymerase I Promoter Escape";"PKMTs methylate histone lysines";"DNA methylation";"Amyloid fiber formation";"SUMOylation of chromatin organization proteins";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NoRC negatively regulates rRNA expression";"Formation of the beta-catenin:TCF transactivating complex";"HCMV Early Events";"DNA Damage/Telomere Stress Induced Senescence";"Condensation of Prophase Chromosomes";"Recognition and association of DNA glycosylase with site containing an affected purine";"Oxidative Stress Induced Senescence";"Cleavage of the damaged purine";"PRC2 methylates histones and DNA";"B-WICH complex positively regulates rRNA expression";"RMTs methylate histone arginines";"HCMV Late Events";"HDMs demethylate histones";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Deposition of new CENPA-containing nucleosomes at the centromere";"Transcriptional regulation of granulopoiesis";"Meiotic recombination";"Meiotic synapsis";"HATs acetylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDACs deacetylate histones";"Estrogen-dependent gene expression";"Nonhomologous End-Joining (NHEJ)";"Pre-NOTCH Transcription and Translation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation by small RNAs";"RNA Polymerase I Promoter Opening";"SIRT1 negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Packaging Of Telomere Ends"
Lalb_12255	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
Lalb_14558	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
Lalb_03332	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
Lalb_03470	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
Lalb_03668	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
Lalb_09166	16	Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557	"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis"
Lalb_09183	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
Lalb_09812	1	MetaCyc: PWY-7511	"Protein ubiquitination"
Lalb_04484	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
Lalb_03501	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
Lalb_00933	7	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs"
Lalb_08281	7	Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
Lalb_12213	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
Lalb_13270	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
Lalb_08328	5	Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5610787;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684	"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Hedgehog 'off' state";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state"
Lalb_10131	18	Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-167160;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-167290	"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation"
Lalb_07729	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
Lalb_02161	6	MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis"
Lalb_02649	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
Lalb_12064	13	KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2022857;KEGG: 00513+3.2.1.52	"Other glycan degradation";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Keratan sulfate degradation";"Various types of N-glycan biosynthesis"
Lalb_07216	6	Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72649	"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation"
Lalb_06083	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
Lalb_02651	13	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-6791226	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_01551	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
Lalb_09156	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
Lalb_12054	1	MetaCyc: PWY-7511	"Protein ubiquitination"
Lalb_02939	83	Reactome: R-HSA-391160;Reactome: R-HSA-8853338;Reactome: R-HSA-5655302;Reactome: R-HSA-74749;Reactome: R-HSA-9034864;Reactome: R-HSA-9607240;Reactome: R-HSA-112412;Reactome: R-HSA-5654700;Reactome: R-HSA-2428933;Reactome: R-HSA-5654720;Reactome: R-HSA-2730905;Reactome: R-HSA-9664565;Reactome: R-HSA-180292;Reactome: R-HSA-1236382;Reactome: R-HSA-5673001;Reactome: R-HSA-6807004;Reactome: R-HSA-8851907;Reactome: R-HSA-1963642;Reactome: R-HSA-5655253;Reactome: R-HSA-8851805;Reactome: R-HSA-9027284;Reactome: R-HSA-1433557;Reactome: R-HSA-8875656;Reactome: R-HSA-1839117;Reactome: R-HSA-1963640;Reactome: R-HSA-1250196;Reactome: R-HSA-5654699;Reactome: R-HSA-8856828;Reactome: R-HSA-210993;Reactome: R-HSA-8875360;Reactome: R-HSA-8875555;Reactome: R-HSA-5654688;Reactome: R-HSA-9026519;Reactome: R-HSA-5654733;Reactome: R-HSA-8856825;Reactome: R-HSA-5654710;Reactome: R-HSA-5654706;Reactome: R-HSA-167044;Reactome: R-HSA-2219530;Reactome: R-HSA-8865999;Reactome: R-HSA-5654712;Reactome: R-HSA-74751;Reactome: R-HSA-5654693;Reactome: R-HSA-182971;Reactome: R-HSA-1257604;Reactome: R-HSA-2029482;Reactome: R-HSA-186763;Reactome: R-HSA-5637810;Reactome: R-HSA-8983432;Reactome: R-HSA-1250347;Reactome: R-HSA-9645135;Reactome: R-HSA-2871796;Reactome: R-HSA-8853334;Reactome: R-HSA-388841;Reactome: R-HSA-375165;Reactome: R-HSA-1295596;Reactome: R-HSA-912526;Reactome: R-HSA-9028731;Reactome: R-HSA-2179392;Reactome: R-HSA-2871809;Reactome: R-HSA-109704;Reactome: R-HSA-5654695;Reactome: R-HSA-912631;Reactome: R-HSA-983695;Reactome: R-HSA-2424491;Reactome: R-HSA-180336;Reactome: R-HSA-5654689;Reactome: R-HSA-5654719;Reactome: R-HSA-5654727;Reactome: R-HSA-512988;Reactome: R-HSA-6811558;Reactome: R-HSA-1433559;Reactome: R-HSA-5663213;Reactome: R-HSA-389359;Reactome: R-HSA-5655291;Reactome: R-HSA-5654704;Reactome: R-HSA-8853659;Reactome: R-HSA-354194;Reactome: R-HSA-179812;Reactome: R-HSA-5654726;Reactome: R-HSA-9634285;Reactome: R-HSA-9028335;Reactome: R-HSA-5654732	"Signal regulatory protein family interactions";"Signaling by FGFR3 point mutants in cancer";"Signaling by FGFR1 in disease";"Signal attenuation";"Activated NTRK3 signals through RAS";"FLT3 Signaling";"SOS-mediated signalling";"FRS-mediated FGFR2 signaling";"SHC-related events triggered by IGF1R";"PI-3K cascade:FGFR4";"Role of LAT2/NTAL/LAB on calcium mobilization";"Signaling by ERBB2 KD Mutants";"GAB1 signalosome";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"RAF/MAP kinase cascade";"Negative regulation of MET activity";"MET activates PI3K/AKT signaling";"PI3K events in ERBB2 signaling";"Signaling by FGFR2 in disease";"MET activates RAS signaling";"Erythropoietin activates RAS";"Signaling by SCF-KIT";"MET receptor recycling";"Signaling by cytosolic FGFR1 fusion mutants";"GRB2 events in ERBB2 signaling";"SHC1 events in ERBB2 signaling";"SHC-mediated cascade:FGFR2";"Clathrin-mediated endocytosis";"Tie2 Signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"MET activates RAP1 and RAC1";"SHC-mediated cascade:FGFR1";"Activated NTRK2 signals through RAS";"Negative regulation of FGFR4 signaling";"Cargo recognition for clathrin-mediated endocytosis";"PI-3K cascade:FGFR3";"FRS-mediated FGFR3 signaling";"Signalling to RAS";"Constitutive Signaling by Aberrant PI3K in Cancer";"MET activates PTPN11";"FRS-mediated FGFR4 signaling";"Insulin receptor signalling cascade";"FRS-mediated FGFR1 signaling";"EGFR downregulation";"PIP3 activates AKT signaling";"Regulation of actin dynamics for phagocytic cup formation";"Downstream signal transduction";"Constitutive Signaling by EGFRvIII";"Interleukin-15 signaling";"SHC1 events in ERBB4 signaling";"STAT5 Activation";"FCERI mediated MAPK activation";"Signaling by FGFR3 fusions in cancer";"Costimulation by the CD28 family";"NCAM signaling for neurite out-growth";"Spry regulation of FGF signaling";"Interleukin receptor SHC signaling";"Activated NTRK2 signals through FRS2 and FRS3";"EGFR Transactivation by Gastrin";"FCERI mediated Ca+2 mobilization";"PI3K Cascade";"PI-3K cascade:FGFR2";"Regulation of signaling by CBL";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"DAP12 signaling";"SHC1 events in EGFR signaling";"PI-3K cascade:FGFR1";"SHC-mediated cascade:FGFR4";"Negative regulation of FGFR2 signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Regulation of KIT signaling";"RHO GTPases Activate WASPs and WAVEs";"CD28 dependent Vav1 pathway";"Signaling by FGFR4 in disease";"SHC-mediated cascade:FGFR3";"RET signaling";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"GRB2 events in EGFR signaling";"Negative regulation of FGFR1 signaling";"Constitutive Signaling by Overexpressed ERBB2";"Activated NTRK2 signals through PI3K";"Negative regulation of FGFR3 signaling"
Lalb_03198	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
Lalb_00176	1	Reactome: R-HSA-6803529	"FGFR2 alternative splicing"
Lalb_03884	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
Lalb_09466	27	Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-3108214;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-168271	"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"snRNP Assembly";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus"
Lalb_03734	3	KEGG: 00620+4.4.1.5;MetaCyc: PWY-5386;Reactome: R-HSA-70268	"Pyruvate metabolism";"Methylglyoxal degradation I";"Pyruvate metabolism"
Lalb_01883	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
Lalb_05547	56	Reactome: R-HSA-8854050;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-174113;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-187577	"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RAS by GAPs";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21"
Lalb_03781	42	Reactome: R-HSA-1221632;Reactome: R-HSA-3214847;Reactome: R-HSA-9616222;Reactome: R-HSA-912446;Reactome: R-HSA-9018519;Reactome: R-HSA-5693571;Reactome: R-HSA-8939236;Reactome: R-HSA-3214815;Reactome: R-HSA-73728;Reactome: R-HSA-2559582;Reactome: R-HSA-5578749;Reactome: R-HSA-427389;Reactome: R-HSA-1912408;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-427359;Reactome: R-HSA-171306;Reactome: R-HSA-5693565;Reactome: R-HSA-5625886;Reactome: R-HSA-5334118;Reactome: R-HSA-110329;Reactome: R-HSA-3214841;Reactome: R-HSA-73772;Reactome: R-HSA-201722;Reactome: R-HSA-5617472;Reactome: R-HSA-427413;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-977225;Reactome: R-HSA-8936459;Reactome: R-HSA-212300;Reactome: R-HSA-5250924;Reactome: R-HSA-110330;Reactome: R-HSA-2299718;Reactome: R-HSA-2559580;Reactome: R-HSA-2559586;Reactome: R-HSA-110331;Reactome: R-HSA-110328;Reactome: R-HSA-606279;Reactome: R-HSA-3214842;Reactome: R-HSA-9610379;Reactome: R-HSA-3214858	"Meiotic synapsis";"HATs acetylate histones";"Transcriptional regulation of granulopoiesis";"Meiotic recombination";"Estrogen-dependent gene expression";"Nonhomologous End-Joining (NHEJ)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDACs deacetylate histones";"RNA Polymerase I Promoter Opening";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation by small RNAs";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Pre-NOTCH Transcription and Translation";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"SIRT1 negatively regulates rRNA expression";"Packaging Of Telomere Ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"DNA methylation";"Cleavage of the damaged pyrimidine";"PKMTs methylate histone lysines";"RNA Polymerase I Promoter Escape";"Formation of the beta-catenin:TCF transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NoRC negatively regulates rRNA expression";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Amyloid fiber formation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PRC2 methylates histones and DNA";"B-WICH complex positively regulates rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected purine";"Condensation of Prophase Chromosomes";"Oxidative Stress Induced Senescence";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Deposition of new CENPA-containing nucleosomes at the centromere";"HDMs demethylate histones";"HCMV Late Events";"RMTs methylate histone arginines"
Lalb_04855	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
Lalb_03045	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
Lalb_04515	6	MetaCyc: PWY-6368;Reactome: R-HSA-1660516;KEGG: 00562+3.1.3.66;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1855183;Reactome: R-HSA-1660499	"3-phosphoinositide degradation";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane"
Lalb_13850	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
Lalb_11909	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
Lalb_06612	3	Reactome: R-HSA-2672351;Reactome: R-HSA-1268020;Reactome: R-HSA-8949613	"Stimuli-sensing channels";"Mitochondrial protein import";"Cristae formation"
Lalb_13384	1	MetaCyc: PWY-7511	"Protein ubiquitination"
Lalb_13565	3	Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"snRNP Assembly";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
Lalb_03210	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
Lalb_05489	6	MetaCyc: PWY-5381;KEGG: 00760+6.3.1.5;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5653;MetaCyc: PWY-7761;Reactome: R-HSA-196807	"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism"
Lalb_04311	3	Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395	"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER"
Lalb_09652	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
Lalb_10905	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_05916	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
Lalb_08106	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
Lalb_04687	56	Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-9010553;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-174113;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978	"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"Regulation of expression of SLITs and ROBOs";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"Degradation of AXIN";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Regulation of PTEN stability and activity";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF-beta-TrCP mediated degradation of Emi1";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)"
Lalb_00703	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
Lalb_09857	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
Lalb_07070	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
Lalb_01957	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
Lalb_01027	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
Lalb_04691	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
Lalb_01133	3	Reactome: R-HSA-9033807;MetaCyc: PWY-7831;MetaCyc: PWY-7833	"ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)"
Lalb_03905	4	Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437	"UCH proteinases";"HATs acetylate histones";"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation"
Lalb_01411	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
Lalb_08127	1	Reactome: R-HSA-71288	"Creatine metabolism"
Lalb_13916	3	KEGG: 00480+1.11.1.15;Reactome: R-HSA-5628897;Reactome: R-HSA-3299685	"Glutathione metabolism";"TP53 Regulates Metabolic Genes";"Detoxification of Reactive Oxygen Species"
Lalb_02088	5	Reactome: R-HSA-3247509;Reactome: R-HSA-3214858;Reactome: R-HSA-1266695;Reactome: R-HSA-201722;Reactome: R-HSA-8939243	"Chromatin modifying enzymes";"RMTs methylate histone arginines";"Interleukin-7 signaling";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
Lalb_07570	27	Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-170822;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-168276	"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"snRNP Assembly";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways"
Lalb_08644	9	Reactome: R-HSA-5696395;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-8951664;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Formation of Incision Complex in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Neddylation";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Dual incision in TC-NER";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
Lalb_02349	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
Lalb_01111	10	KEGG: 00564+2.3.1.15;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-8053;Reactome: R-HSA-1483166	"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Synthesis of PA"
Lalb_13517	1	Reactome: R-HSA-71288	"Creatine metabolism"
Lalb_11341	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_02139	179	Reactome: R-HSA-168638;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-2173788;Reactome: R-HSA-975144;Reactome: R-HSA-5684264;Reactome: R-HSA-5610783;Reactome: R-HSA-5654726;Reactome: R-HSA-5357905;Reactome: R-HSA-5689896;Reactome: R-HSA-8876493;Reactome: R-HSA-5654732;Reactome: R-HSA-9013507;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-110312;Reactome: R-HSA-180534;Reactome: R-HSA-8866652;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-179409;Reactome: R-HSA-9033241;Reactome: R-HSA-917937;Reactome: R-HSA-8863795;Reactome: R-HSA-2122948;Reactome: R-HSA-1253288;Reactome: R-HSA-5678895;Reactome: R-HSA-2173796;Reactome: R-HSA-4641257;Reactome: R-HSA-5696395;Reactome: R-HSA-2672351;Reactome: R-HSA-937042;Reactome: R-HSA-174178;Reactome: R-HSA-2644606;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768;Reactome: R-HSA-1358803;Reactome: R-HSA-5696397;Reactome: R-HSA-2173795;Reactome: R-HSA-6782210;Reactome: R-HSA-182971;Reactome: R-HSA-9636383;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-168928;Reactome: R-HSA-936964;Reactome: R-HSA-6781827;Reactome: R-HSA-975110;Reactome: R-HSA-3322077;Reactome: R-HSA-168927;Reactome: R-HSA-6804760;Reactome: R-HSA-5696400;Reactome: R-HSA-8856825;Reactome: R-HSA-5654733;Reactome: R-HSA-5693565;Reactome: R-HSA-2173791;Reactome: R-HSA-110320;Reactome: R-HSA-5655862;Reactome: R-HSA-917729;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-9633012;Reactome: R-HSA-6783310;Reactome: R-HSA-8941858;Reactome: R-HSA-532668;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-2691232;Reactome: R-HSA-5693607;Reactome: R-HSA-72706;Reactome: R-HSA-174113;Reactome: R-HSA-5689901;Reactome: R-HSA-5656169;Reactome: R-HSA-9615710;Reactome: R-HSA-6807004;Reactome: R-HSA-187577;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9646399;Reactome: R-HSA-209543;Reactome: R-HSA-6782135;Reactome: R-HSA-2408557;Reactome: R-HSA-5689603;Reactome: R-HSA-1799339;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-69017;Reactome: R-HSA-3769402;Reactome: R-HSA-69541;Reactome: R-HSA-9010553;Reactome: R-HSA-209560;Reactome: R-HSA-1234176;Reactome: R-HSA-975957;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-2559580;Reactome: R-HSA-937039;Reactome: R-HSA-8866654;Reactome: R-HSA-2894862;Reactome: R-HSA-936440;Reactome: R-HSA-4641263;Reactome: R-HSA-937072;Reactome: R-HSA-445989;Reactome: R-HSA-5607761;Reactome: R-HSA-156827;Reactome: R-HSA-8849469;Reactome: R-HSA-2979096;Reactome: R-HSA-205043;Reactome: R-HSA-68949;Reactome: R-HSA-5685942;Reactome: R-HSA-912631;Reactome: R-HSA-69601;Reactome: R-HSA-9014325;Reactome: R-HSA-6804756;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-2559582;Reactome: R-HSA-69231;Reactome: R-HSA-9637628;Reactome: R-HSA-201681;Reactome: R-HSA-5654727;Reactome: R-HSA-192823;Reactome: R-HSA-2122947;Reactome: R-HSA-349425;Reactome: R-HSA-2559585;Reactome: R-HSA-2871837;Reactome: R-HSA-9013973;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-4641258;Reactome: R-HSA-1295596;Reactome: R-HSA-937041;Reactome: R-HSA-5607764;Reactome: R-HSA-72689;Reactome: R-HSA-5357956;Reactome: R-HSA-1236974;Reactome: R-HSA-5205685;Reactome: R-HSA-975163;Reactome: R-HSA-450302;Reactome: R-HSA-5675482;Reactome: R-HSA-2565942;Reactome: R-HSA-8948747;Reactome: R-HSA-162588;Reactome: R-HSA-4608870;Reactome: R-HSA-8875360;Reactome: R-HSA-901032;Reactome: R-HSA-5656121;Reactome: R-HSA-3134975;Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-6804757;Reactome: R-HSA-174490;Reactome: R-HSA-9613829;Reactome: R-HSA-8856828;Reactome: R-HSA-110314;Reactome: R-HSA-450408;Reactome: R-HSA-1169408;Reactome: R-HSA-5689877;Reactome: R-HSA-174184;Reactome: R-HSA-450321;Reactome: R-HSA-977225;Reactome: R-HSA-5658442;Reactome: R-HSA-1236382;Reactome: R-HSA-8939902;Reactome: R-HSA-9645460;Reactome: R-HSA-3785653;Reactome: R-HSA-72764;Reactome: R-HSA-175474;Reactome: R-HSA-400253;Reactome: R-HSA-975956;Reactome: R-HSA-69481;Reactome: R-HSA-5675221	"NOD1/2 Signaling Pathway";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downregulation of TGF-beta receptor signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Degradation of GLI2 by the proteasome";"Negative regulation of FGFR1 signaling";"Regulation of TNFR1 signaling";"Ovarian tumor domain proteases";"InlA-mediated entry of Listeria monocytogenes into host cells";"Negative regulation of FGFR3 signaling";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Translesion synthesis by REV1";"Vpu mediated degradation of CD4";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC-Cdc20 mediated degradation of Nek2A";"Peroxisomal protein import";"Iron uptake and transport";"Downregulation of ERBB2 signaling";"Activated NOTCH1 Transmits Signal to the Nucleus";"Downregulation of ERBB4 signaling";"Defective CFTR causes cystic fibrosis";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Degradation of AXIN";"Formation of Incision Complex in GG-NER";"Stimuli-sensing channels";"IRAK2 mediated activation of TAK1 complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downregulation of ERBB2:ERBB3 signaling";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Gap-filling DNA repair synthesis and ligation in TC-NER";"EGFR downregulation";"Prevention of phagosomal-lysosomal fusion";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Glycogen synthesis";"TICAM1, RIP1-mediated IKK complex recruitment";"Regulation of TP53 Activity through Methylation";"Dual Incision in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of FGFR4 signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Translesion Synthesis by POLH";"Translesion synthesis by POLK";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Fanconi Anemia Pathway";"Regulation of RUNX3 expression and activity";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Processing of DNA double-strand break ends";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SCF-beta-TrCP mediated degradation of Emi1";"Metalloprotease DUBs";"Termination of translesion DNA synthesis";"Late endosomal microautophagy";"Negative regulation of MET activity";"SCF(Skp2)-mediated degradation of p27/p21";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Aggrephagy";"p75NTR recruits signalling complexes";"Dual incision in TC-NER";"Selenocysteine synthesis";"UCH proteinases";"SRP-dependent cotranslational protein targeting to membrane";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"CDK-mediated phosphorylation and removal of Cdc6";"Deactivation of the beta-catenin transactivating complex";"Stabilization of p53";"Regulation of expression of SLITs and ROBOs";"NF-kB is activated and signals survival";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"Oxidative Stress Induced Senescence";"IRAK1 recruits IKK complex";"E3 ubiquitin ligases ubiquitinate target proteins";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Negative regulators of DDX58/IFIH1 signaling";"Regulation of FZD by ubiquitination";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Dectin-1 mediated noncanonical NF-kB signaling";"L13a-mediated translational silencing of Ceruloplasmin expression";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Orc1 removal from chromatin";"HDR through Homologous Recombination (HRR)";"Regulation of signaling by CBL";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Regulation of TP53 Activity through Phosphorylation";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Senescence-Associated Secretory Phenotype (SASP)";"Cyclin D associated events in G1";"Modulation by Mtb of host immune system";"TCF dependent signaling in response to WNT";"Negative regulation of FGFR2 signaling";"Viral mRNA Translation";"NOTCH1 Intracellular Domain Regulates Transcription";"Autodegradation of the E3 ubiquitin ligase COP1";"Oncogene Induced Senescence";"FCERI mediated NF-kB activation";"TICAM1-dependent activation of IRF3/IRF7";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Degradation of DVL";"Spry regulation of FGF signaling";"IKK complex recruitment mediated by RIP1";"CLEC7A (Dectin-1) signaling";"Formation of a pool of free 40S subunits";"TNFR1-induced NFkappaB signaling pathway";"ER-Phagosome pathway";"Pink/Parkin Mediated Mitophagy";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"activated TAK1 mediates p38 MAPK activation";"Regulation of necroptotic cell death";"Regulation of PLK1 Activity at G2/M Transition";"Regulation of PTEN localization";"Budding and maturation of HIV virion";"Asymmetric localization of PCP proteins";"InlB-mediated entry of Listeria monocytogenes into host cell";"ER Quality Control Compartment (ERQC)";"Translesion synthesis by POLI";"Regulation of innate immune responses to cytosolic DNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of TP53 Degradation";"Membrane binding and targetting of GAG proteins";"Chaperone Mediated Autophagy";"Clathrin-mediated endocytosis";"Recognition of DNA damage by PCNA-containing replication complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ISG15 antiviral mechanism";"Josephin domain DUBs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Amyloid fiber formation";"Regulation of RAS by GAPs";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Regulation of RUNX2 expression and activity";"Alpha-protein kinase 1 signaling pathway";"Myoclonic epilepsy of Lafora";"Eukaryotic Translation Termination";"Assembly Of The HIV Virion";"Circadian Clock";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"G2/M Checkpoints";"Negative regulation of MAPK pathway"
Lalb_08032	9	Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-76042	"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
Lalb_07957	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
Lalb_09930	10	Reactome: R-HSA-2514853;Reactome: R-HSA-6814122;Reactome: R-HSA-445144;Reactome: R-HSA-8934903;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-201688;Reactome: R-HSA-8939243;Reactome: R-HSA-1483191;Reactome: R-HSA-6804756	"Condensation of Prometaphase Chromosomes";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Signal transduction by L1";"Receptor Mediated Mitophagy";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Synthesis of PC";"Regulation of TP53 Activity through Phosphorylation"
Lalb_03837	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
Lalb_12680	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
Lalb_00319	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
Lalb_14074	10	Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-9018519;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-75953	"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Estrogen-dependent gene expression";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation"
Lalb_07434	4	Reactome: R-HSA-8874211;Reactome: R-HSA-1655829;Reactome: R-HSA-8963889;Reactome: R-HSA-381033	"CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Assembly of active LPL and LIPC lipase complexes";"ATF6 (ATF6-alpha) activates chaperones"
Lalb_09056	1	Reactome: R-HSA-8951664	"Neddylation"
Lalb_01478	7	Reactome: R-HSA-446193;Reactome: R-HSA-5633231;KEGG: 00550+2.4.1.227;MetaCyc: PWY-6471;MetaCyc: PWY-6470;MetaCyc: PWY-6385;MetaCyc: PWY-5265	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis II (staphylococci)"
Lalb_06259	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
Lalb_13780	2	Reactome: R-HSA-1369062;Reactome: R-HSA-6798695	"ABC transporters in lipid homeostasis";"Neutrophil degranulation"
Lalb_06138	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
Lalb_04713	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
Lalb_06532	18	Reactome: R-HSA-1482925;MetaCyc: PWY-6803;Reactome: R-HSA-1482801;MetaCyc: PWY-7409;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;Reactome: R-HSA-1482839;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4	"Acyl chain remodelling of PG";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Acyl chain remodelling of PE";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Synthesis of PA";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism"
Lalb_01625	12	MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-7783;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8051	"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I"
Lalb_10619	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
Lalb_13166	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
Lalb_01821	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
Lalb_12059	7	Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73980	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination"
Lalb_10447	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
Lalb_11471	1	Reactome: R-HSA-6798163	"Choline catabolism"
Lalb_12194	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
Lalb_06301	1	MetaCyc: PWY-7511	"Protein ubiquitination"
Lalb_09805	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
Lalb_03546	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
Lalb_07057	7	KEGG: 00330+2.5.1.22;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.22	"Arginine and proline metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism"
Lalb_03567	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
Lalb_11027	5	Reactome: R-HSA-3247509;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243;Reactome: R-HSA-1266695;Reactome: R-HSA-201722	"Chromatin modifying enzymes";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling";"Formation of the beta-catenin:TCF transactivating complex"
Lalb_14093	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
Lalb_05282	1	Reactome: R-HSA-3295583	"TRP channels"
Lalb_01752	6	Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-380994	"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
Lalb_09240	15	Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-6807505	"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes"
Lalb_09244	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
Lalb_01316	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
Lalb_04949	1	Reactome: R-HSA-400253	"Circadian Clock"
Lalb_08943	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_13919	56	Reactome: R-HSA-9010553;Reactome: R-HSA-5362768;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-69017;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-195253;Reactome: R-HSA-5607761;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783	"Regulation of expression of SLITs and ROBOs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of AXIN";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Degradation of beta-catenin by the destruction complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome"
Lalb_14146	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
Lalb_04064	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
Lalb_02530	6	Reactome: R-HSA-202040;Reactome: R-HSA-8851805;Reactome: R-HSA-383280;Reactome: R-HSA-418594;Reactome: R-HSA-112043;Reactome: R-HSA-6814122	"G-protein activation";"MET activates RAS signaling";"Nuclear Receptor transcription pathway";"G alpha (i) signalling events";"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
Lalb_07564	25	Reactome: R-HSA-8939243;Reactome: R-HSA-8939902;Reactome: R-HSA-8939247;Reactome: R-HSA-8939245;Reactome: R-HSA-9616222;Reactome: R-HSA-9018519;Reactome: R-HSA-8877330;Reactome: R-HSA-8941284;Reactome: R-HSA-8940973;Reactome: R-HSA-8941333;Reactome: R-HSA-8931987;Reactome: R-HSA-8936459;Reactome: R-HSA-8939242;Reactome: R-HSA-8939236;Reactome: R-HSA-8941858;Reactome: R-HSA-8941332;Reactome: R-HSA-8941326;Reactome: R-HSA-8934593;Reactome: R-HSA-8939256;Reactome: R-HSA-8951936;Reactome: R-HSA-8935964;Reactome: R-HSA-8949275;Reactome: R-HSA-8878166;Reactome: R-HSA-8939246;Reactome: R-HSA-8951911	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 regulates transcription of genes involved in BCR signaling";"Transcriptional regulation of granulopoiesis";"Estrogen-dependent gene expression";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX2 regulates chondrocyte maturation";"RUNX2 regulates osteoblast differentiation";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX3 expression and activity";"RUNX2 regulates genes involved in cell migration";"RUNX2 regulates bone development";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX3 regulates p14-ARF";"RUNX1 regulates expression of components of tight junctions";"RUNX3 Regulates Immune Response and Cell Migration";"Transcriptional regulation by RUNX2";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX3 regulates RUNX1-mediated transcription"
Lalb_01956	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
Lalb_14100	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_01683	5	Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-1989781;Reactome: R-HSA-380994;Reactome: R-HSA-9614657	"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes"
Lalb_04980	31	MetaCyc: PWY-5367;MetaCyc: PWY-8049;MetaCyc: PWY-5366;MetaCyc: PWY-6519;MetaCyc: PWY-5994;Reactome: R-HSA-9029558;MetaCyc: PWY-5142;MetaCyc: PWY-7858;MetaCyc: PWY-7388;MetaCyc: PWY-8012;MetaCyc: PWYG-321;Reactome: R-HSA-75105;Reactome: R-HSA-163765;MetaCyc: PWY-6799;MetaCyc: PWY-7746;MetaCyc: PWY-4381;MetaCyc: PWY-5147;Reactome: R-HSA-2426168;MetaCyc: PWY-7663;MetaCyc: PWY-8047;MetaCyc: PWY-5989;MetaCyc: PWY-5966-1;Reactome: R-HSA-199220;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6282;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7664;MetaCyc: PWY-5971;MetaCyc: PWY-6113;MetaCyc: PWY-5973;MetaCyc: PWY-7723	"Petroselinate biosynthesis";"Pederin biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"8-amino-7-oxononanoate biosynthesis I";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"(5Z)-dodecenoate biosynthesis II";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Mupirocin biosynthesis";"";"Fatty acyl-CoA biosynthesis";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (plant mitochondria)";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Oleate biosynthesis I (plants)";"Activation of gene expression by SREBF (SREBP)";"Gondoate biosynthesis (anaerobic)";"Bryostatin biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"Fatty acid biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Biotin metabolism";"Oleate biosynthesis IV (anaerobic)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Superpathway of mycolate biosynthesis";"Cis-vaccenate biosynthesis";"Bacterial bioluminescence"
Lalb_12782	5	MetaCyc: PWY-6855;MetaCyc: PWY-6906;Reactome: R-HSA-70171;MetaCyc: PWY-5514;KEGG: 00520+3.5.99.6	"Chitin degradation I (archaea)";"Chitin derivatives degradation";"Glycolysis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism"
Lalb_08712	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
Lalb_10519	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
Lalb_03639	3	KEGG: 00051+1.1.1.271;KEGG: 00520+1.1.1.271;Reactome: R-HSA-6787639	"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis"
Lalb_07566	6	Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex"
Lalb_00569	4	MetaCyc: PWY-5189;MetaCyc: PWY-5188;KEGG: 00860+4.2.1.75;Reactome: R-HSA-189451	"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
Lalb_03019	4	Reactome: R-HSA-8875656;Reactome: R-HSA-8875555;Reactome: R-HSA-912631;Reactome: R-HSA-186763	"MET receptor recycling";"MET activates RAP1 and RAC1";"Regulation of signaling by CBL";"Downstream signal transduction"
Lalb_01764	9	Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)"
Lalb_14461	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
Lalb_00661	3	KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857;Reactome: R-HSA-192456	"Glycerolipid metabolism";"Retinol biosynthesis";"Digestion of dietary lipid"
Lalb_09603	4	Reactome: R-HSA-3304356;Reactome: R-HSA-3656532;Reactome: R-HSA-2173789;Reactome: R-HSA-2173788	"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"Downregulation of TGF-beta receptor signaling"
Lalb_08185	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
Lalb_14309	9	Reactome: R-HSA-2022928;Reactome: R-HSA-1971475;Reactome: R-HSA-4420332;Reactome: R-HSA-975634;Reactome: R-HSA-2024096;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-3560783	"HS-GAG biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Retinoid metabolism and transport";"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type"
Lalb_01924	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
Lalb_04177	3	Reactome: R-HSA-5689880;Reactome: R-HSA-6783310;Reactome: R-HSA-110314	"Ub-specific processing proteases";"Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex"
Lalb_05796	1	MetaCyc: PWY-7379	"Mrna capping II"
Lalb_03949	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
Lalb_08029	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
Lalb_06075	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
Lalb_11158	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
Lalb_02631	4	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes"
Lalb_04238	10	Reactome: R-HSA-70263;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-6886;MetaCyc: PWY-1042;KEGG: 00710+2.7.2.3;MetaCyc: PWY-6901;MetaCyc: PWY-7003;KEGG: 00010+2.7.2.3;MetaCyc: PWY-8004	"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I"
Lalb_12183	5	Reactome: R-HSA-1834949;Reactome: R-HSA-3270619;Reactome: R-HSA-5693571;Reactome: R-HSA-6798695;Reactome: R-HSA-164843	"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)";"Neutrophil degranulation";"2-LTR circle formation"
Lalb_12619	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
Lalb_11095	5	Reactome: R-HSA-212300;Reactome: R-HSA-427413;Reactome: R-HSA-5334118;Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37	"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression";"DNA methylation";"SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism"
Lalb_13879	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
Lalb_00715	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
Lalb_06730	8	MetaCyc: PWY-5686;MetaCyc: PWY-5154;KEGG: 00250+6.3.5.5;MetaCyc: PWY-7790;KEGG: 00240+3.5.2.3;MetaCyc: PWY-7400;MetaCyc: PWY-7791;KEGG: 00240+6.3.5.5	"UMP biosynthesis I";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis II";"Pyrimidine metabolism";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis III";"Pyrimidine metabolism"
Lalb_02172	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
Lalb_06430	33	Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-3108214;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-159231;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-5578749;Reactome: R-HSA-2467813;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-168276	"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transcriptional regulation by small RNAs";"Separation of Sister Chromatids";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways"
Lalb_10005	56	Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978	"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RAS by GAPs";"Degradation of AXIN";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)"
Lalb_10275	2	Reactome: R-HSA-5689880;Reactome: R-HSA-110320	"Ub-specific processing proteases";"Translesion Synthesis by POLH"
Lalb_04516	3	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807;MetaCyc: PWY-7805	"Oxidative phosphorylation";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation"
Lalb_02405	26	Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-389960;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-437239;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-9619483;Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497	"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Formation of tubulin folding intermediates by CCT/TriC";"Cilium Assembly";"Aggrephagy";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Recycling pathway of L1";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"Activation of AMPK downstream of NMDARs";"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
Lalb_02670	1	Reactome: R-HSA-8949613	"Cristae formation"
Lalb_02855	11	Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-205043;Reactome: R-HSA-9013700;Reactome: R-HSA-2894862;Reactome: R-HSA-3928665;Reactome: R-HSA-9017802;Reactome: R-HSA-193692;Reactome: R-HSA-9013507;Reactome: R-HSA-1251985;Reactome: R-HSA-2644606	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NRIF signals cell death from the nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"Noncanonical activation of NOTCH3";"Regulated proteolysis of p75NTR";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
Lalb_11912	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
Lalb_07400	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
Lalb_04524	5	Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-983231;Reactome: R-HSA-2132295	"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Factors involved in megakaryocyte development and platelet production";"MHC class II antigen presentation"
Lalb_13983	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
Lalb_03839	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
Lalb_08299	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway"
Lalb_10229	5	Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9615710	"Budding and maturation of HIV virion";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy"
Lalb_13272	13	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-156827	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression"
Lalb_01450	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
Lalb_02338	5	Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-196108	"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis"
Lalb_04245	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
Lalb_12955	14	MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-6433	"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)"
Lalb_03178	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
Lalb_09608	3	KEGG: 00130+1.17.4.4;Reactome: R-HSA-6806664;MetaCyc: PWY-7999	"Ubiquinone and other terpenoid-quinone biosynthesis";"Metabolism of vitamin K";"Vitamin K-epoxide cycle"
Lalb_00191	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
Lalb_03763	5	MetaCyc: PWY-7268;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7269	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
Lalb_06895	6	Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994	"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
Lalb_03796	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
Lalb_12500	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
Lalb_13216	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
Lalb_11670	2	MetaCyc: PWY-7533;Reactome: R-HSA-1268020	"Gliotoxin biosynthesis";"Mitochondrial protein import"
Lalb_05824	1	Reactome: R-HSA-525793	"Myogenesis"
Lalb_13788	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
Lalb_06152	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
Lalb_09126	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
Lalb_00217	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
Lalb_13652	10	MetaCyc: PWY-6174;Reactome: R-HSA-1989781;MetaCyc: PWY-7571;KEGG: 00650+2.3.3.10;KEGG: 00072+2.3.3.10;KEGG: 00900+2.3.3.10;KEGG: 00280+2.3.3.10;MetaCyc: PWY-922;MetaCyc: PWY-7391;MetaCyc: PWY-7524	"Mevalonate pathway II (archaea)";"PPARA activates gene expression";"Ferrichrome A biosynthesis";"Butanoate metabolism";"Synthesis and degradation of ketone bodies";"Terpenoid backbone biosynthesis";"Valine, leucine and isoleucine degradation";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)"
Lalb_04154	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
Lalb_01714	9	Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172	"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome"
Lalb_02335	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
Lalb_11504	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
Lalb_00751	4	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-202733;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Cell surface interactions at the vascular wall";"Th1 and Th2 cell differentiation"
Lalb_05664	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
Lalb_02606	5	Reactome: R-HSA-199220;KEGG: 00770+2.7.8.7;MetaCyc: PWY-6012-1;MetaCyc: PWY-6289;MetaCyc: PWY-6012	"Vitamin B5 (pantothenate) metabolism";"Pantothenate and CoA biosynthesis";"Acyl carrier protein activation";"Petrobactin biosynthesis";"Acyl carrier protein metabolism"
Lalb_05669	3	Reactome: R-HSA-196780;Reactome: R-HSA-70263;Reactome: R-HSA-3371599	"Biotin transport and metabolism";"Gluconeogenesis";"Defective HLCS causes multiple carboxylase deficiency"
Lalb_14049	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
Lalb_07810	15	Reactome: R-HSA-5693616;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-5693579;Reactome: R-HSA-5685939;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693548;Reactome: R-HSA-5685938;Reactome: R-HSA-2559586;Reactome: R-HSA-912446;Reactome: R-HSA-5693607;Reactome: R-HSA-69473	"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Homologous DNA Pairing and Strand Exchange";"HDR through MMEJ (alt-NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Sensing of DNA Double Strand Breaks";"HDR through Single Strand Annealing (SSA)";"DNA Damage/Telomere Stress Induced Senescence";"Meiotic recombination";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint"
Lalb_07581	27	Reactome: R-HSA-159227;Reactome: R-HSA-72187;Reactome: R-HSA-6803529;Reactome: R-HSA-77595;Reactome: R-HSA-674695;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-72086;Reactome: R-HSA-73856;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-191859;Reactome: R-HSA-72165;Reactome: R-HSA-6807505;Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72203;Reactome: R-HSA-8851708;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167200	"Transport of the SLBP independent Mature mRNA";"mRNA 3'-end processing";"FGFR2 alternative splicing";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Pre-transcription Events";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Capping";"RNA Polymerase II Transcription Termination";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"snRNP Assembly";"mRNA Splicing - Minor Pathway";"RNA polymerase II transcribes snRNA genes";"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Processing of Capped Intron-Containing Pre-mRNA";"Signaling by FGFR2 IIIa TM";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
Lalb_12496	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
Lalb_08459	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
Lalb_13402	9	MetaCyc: PWY-4061;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18;KEGG: 00980+2.5.1.18;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7533;Reactome: R-HSA-156590;MetaCyc: PWY-7112	"Glutathione-mediated detoxification I";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - other enzymes";"Gliotoxin biosynthesis";"Glutathione conjugation";"4-hydroxy-2-nonenal detoxification"
Lalb_01824	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
Lalb_05395	1	Reactome: R-HSA-156588	"Glucuronidation"
Lalb_08789	10	KEGG: 05163+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04150+2.7.11.1;Reactome: R-HSA-444257;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-442742	"Human cytomegalovirus infection";"Recycling pathway of L1";"mTOR signaling pathway";"RSK activation";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling"
Lalb_10719	13	Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72764	"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination"
Lalb_04396	7	Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912	"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane"
Lalb_12558	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
Lalb_06951	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
Lalb_09874	1	Reactome: R-HSA-156588	"Glucuronidation"
Lalb_11196	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
Lalb_13035	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
Lalb_06975	20	Reactome: R-HSA-9033241;MetaCyc: PWY-7854;MetaCyc: PWY-7574;MetaCyc: PWY-7288;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7606;MetaCyc: PWY-7291;MetaCyc: PWY-6920;MetaCyc: PWY-7338;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-5136;MetaCyc: PWY-7007;MetaCyc: PWY-6837;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;MetaCyc: PWY-735	"Peroxisomal protein import";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"alpha-Linolenic acid metabolism";"(5Z)-dodecenoate biosynthesis II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid degradation";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"Jasmonic acid biosynthesis"
Lalb_04419	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_02977	10	Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616	"Meiotic recombination";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange"
Lalb_07567	5	Reactome: R-HSA-6811436;Reactome: R-HSA-6798695;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295	"COPI-independent Golgi-to-ER retrograde traffic";"Neutrophil degranulation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation"
Lalb_11544	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)"
Lalb_07974	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
Lalb_11059	4	Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-77075;MetaCyc: PWY-7375	"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"Mrna capping I"
Lalb_00508	4	Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946	"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin"
Lalb_07456	3	Reactome: R-HSA-1660517;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514	"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane"
Lalb_07054	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
Lalb_13081	1	MetaCyc: PWY-7511	"Protein ubiquitination"
Lalb_00282	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
Lalb_07180	11	Reactome: R-HSA-432040;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-418555	"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway";"PKA activation";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events"
Lalb_09878	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
Lalb_12992	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_01823	8	KEGG: 00010+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-8086;KEGG: 00620+1.1.1.27;KEGG: 00640+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00270+1.1.1.27;Reactome: R-HSA-70268	"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Propanoate metabolism";"Pyruvate fermentation to (S)-lactate";"Cysteine and methionine metabolism";"Pyruvate metabolism"
Lalb_02704	11	Reactome: R-HSA-5693616;Reactome: R-HSA-5358565;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5358606;Reactome: R-HSA-5693607;Reactome: R-HSA-69473	"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint"
Lalb_10521	4	Reactome: R-HSA-389661;KEGG: 00785+2.8.1.8;MetaCyc: PWY-6987;MetaCyc: PWY-7382	"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)"
Lalb_01427	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
Lalb_00781	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
Lalb_14218	1	Reactome: R-HSA-480985	"Synthesis of dolichyl-phosphate-glucose"
Lalb_01001	4	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;Reactome: R-HSA-1237112	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway"
Lalb_11241	5	Reactome: R-HSA-110328;Reactome: R-HSA-5221030;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-3108214	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins"
Lalb_07757	6	MetaCyc: PWY-6952;Reactome: R-HSA-163560;MetaCyc: PWY-4261;Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6118	"Glycerophosphodiester degradation";"Triglyceride catabolism";"Glycerol degradation I";"Synthesis of PA";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle"
Lalb_10740	6	Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-388844	"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
Lalb_07409	1	Reactome: R-HSA-71288	"Creatine metabolism"
Lalb_00412	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
Lalb_11129	12	Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1839117;Reactome: R-HSA-5655302;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-193648;KEGG: 05165+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04714+2.7.11.1	"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"NRAGE signals death through JNK";"Human papillomavirus infection";"Rho GTPase cycle";"Thermogenesis"
Lalb_11191	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
Lalb_10644	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
Lalb_04006	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
Lalb_04307	19	Reactome: R-HSA-525793;Reactome: R-HSA-389359;Reactome: R-HSA-5663213;Reactome: R-HSA-418885;Reactome: R-HSA-194840;Reactome: R-HSA-5663220;Reactome: R-HSA-4420097;Reactome: R-HSA-5625970;Reactome: R-HSA-8964616;Reactome: R-HSA-3928662;Reactome: R-HSA-983231;Reactome: R-HSA-8950505;Reactome: R-HSA-2029482;Reactome: R-HSA-5687128;Reactome: R-HSA-428543;Reactome: R-HSA-5627123;Reactome: R-HSA-182971;Reactome: R-HSA-114604;Reactome: R-HSA-5626467	"Myogenesis";"CD28 dependent Vav1 pathway";"RHO GTPases Activate WASPs and WAVEs";"DCC mediated attractive signaling";"Rho GTPase cycle";"RHO GTPases Activate Formins";"VEGFA-VEGFR2 Pathway";"RHO GTPases activate KTN1";"G beta:gamma signalling through CDC42";"EPHB-mediated forward signaling";"Factors involved in megakaryocyte development and platelet production";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Regulation of actin dynamics for phagocytic cup formation";"MAPK6/MAPK4 signaling";"Inactivation of CDC42 and RAC1";"RHO GTPases activate PAKs";"EGFR downregulation";"GPVI-mediated activation cascade";"RHO GTPases activate IQGAPs"
Lalb_07875	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
Lalb_02675	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
Lalb_02599	11	Reactome: R-HSA-2173796;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-350054;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-9013695;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-72163	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"mRNA Splicing - Major Pathway"
Lalb_01477	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
Lalb_11581	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
Lalb_00502	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
Lalb_12374	1	Reactome: R-HSA-1614558	"Degradation of cysteine and homocysteine"
Lalb_13684	1	Reactome: R-HSA-156588	"Glucuronidation"
Lalb_14596	6	Reactome: R-HSA-3769402;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-8951430	"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling"
Lalb_00949	2	Reactome: R-HSA-171319;Reactome: R-HSA-6790901	"Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol"
Lalb_10473	4	Reactome: R-HSA-2214320;Reactome: R-HSA-1650814;Reactome: R-HSA-2243919;Reactome: R-HSA-1474228	"Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils";"Degradation of the extracellular matrix"
Lalb_04469	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
Lalb_02258	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
Lalb_00717	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
Lalb_10445	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
Lalb_06482	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
Lalb_00457	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
Lalb_01720	33	Reactome: R-HSA-73772;Reactome: R-HSA-6782135;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-6781823;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-5696395;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-73762;Reactome: R-HSA-6782210;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-8939236;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-69231;Reactome: R-HSA-167160;Reactome: R-HSA-73863;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-69273	"RNA Polymerase I Promoter Escape";"Dual incision in TC-NER";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Formation of Incision Complex in GG-NER";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"Cyclin D associated events in G1";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"Cyclin A/B1/B2 associated events during G2/M transition"
Lalb_11576	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
Lalb_11387	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
Lalb_06393	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
Lalb_14579	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
Lalb_11850	5	Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815	"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones"
Lalb_06775	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
Lalb_01060	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
Lalb_05384	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
Lalb_01275	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
Lalb_09551	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
Lalb_06111	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
Lalb_11064	9	Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-69017;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68867	"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"CDK-mediated phosphorylation and removal of Cdc6";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex"
Lalb_05665	5	Reactome: R-HSA-2132295;Reactome: R-HSA-4085001;Reactome: R-HSA-6798695;Reactome: R-HSA-4341670;Reactome: R-HSA-1660662	"MHC class II antigen presentation";"Sialic acid metabolism";"Neutrophil degranulation";"Defective NEU1 causes sialidosis";"Glycosphingolipid metabolism"
Lalb_01705	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
Lalb_10511	8	Reactome: R-HSA-5083629;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;Reactome: R-HSA-5083633;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;Reactome: R-HSA-5173105	"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"O-linked glycosylation"
Lalb_12296	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
Lalb_05018	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
Lalb_11339	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
Lalb_05503	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
Lalb_13888	1	Reactome: R-HSA-611105	"Respiratory electron transport"
Lalb_05733	5	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs";"COPI-mediated anterograde transport"
Lalb_01637	4	KEGG: 00562+1.13.99.1;KEGG: 00053+1.13.99.1;Reactome: R-HSA-1855183;MetaCyc: PWY-4841	"Inositol phosphate metabolism";"Ascorbate and aldarate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)"
Lalb_05254	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
Lalb_01401	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
Lalb_03782	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
Lalb_13165	1	Reactome: R-HSA-8951664	"Neddylation"
Lalb_00188	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
Lalb_03183	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
Lalb_12321	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
Lalb_06494	8	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Activation of RAC1";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
Lalb_11244	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
Lalb_08510	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
Lalb_05070	6	Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-69473	"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint"
Lalb_10818	16	Reactome: R-HSA-174084;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-8853884;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-176409;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-174178	"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Transcriptional Regulation by VENTX";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
Lalb_06829	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
Lalb_07253	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
Lalb_09929	5	MetaCyc: PWY-5188;Reactome: R-HSA-6798695;MetaCyc: PWY-5189;Reactome: R-HSA-189451;KEGG: 00860+4.2.1.24	"Tetrapyrrole biosynthesis I (from glutamate)";"Neutrophil degranulation";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
Lalb_05539	1	MetaCyc: PWY-7511	"Protein ubiquitination"
Lalb_06084	3	Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476	"G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events"
Lalb_13795	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
Lalb_00763	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
Lalb_02356	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
Lalb_08637	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
Lalb_08563	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
Lalb_01081	3	Reactome: R-HSA-2514859;MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
Lalb_00563	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
Lalb_08963	3	KEGG: 00860+1.3.3.4;MetaCyc: PWY-7159;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis"
Lalb_12186	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
Lalb_07245	1	MetaCyc: PWY-7511	"Protein ubiquitination"
Lalb_02418	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
Lalb_05992	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_13874	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
Lalb_13269	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
Lalb_00095	4	MetaCyc: PWY-6906;MetaCyc: PWY-6517;Reactome: R-HSA-446210;KEGG: 00520+2.7.1.59	"Chitin derivatives degradation";"N-acetylglucosamine degradation II";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism"
Lalb_11330	2	KEGG: 00260+2.3.1.29;Reactome: R-HSA-8849175	"Glycine, serine and threonine metabolism";"Threonine catabolism"
Lalb_04237	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
Lalb_00220	6	MetaCyc: PWY-6731;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.1;MetaCyc: PWY-5941;Reactome: R-HSA-70221;MetaCyc: PWY-7238	"Starch degradation III";"Starch degradation V";"Starch and sucrose metabolism";"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II"
Lalb_00890	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_13645	5	KEGG: 00640+1.2.4.4;Reactome: R-HSA-70895;KEGG: 00280+1.2.4.4;MetaCyc: PWY-5046;Reactome: R-HSA-389661	"Propanoate metabolism";"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glyoxylate metabolism and glycine degradation"
Lalb_11547	1	Reactome: R-HSA-156588	"Glucuronidation"
Lalb_09536	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
Lalb_10343	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
Lalb_09463	3	Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-1268020	"Complex I biogenesis";"Respiratory electron transport";"Mitochondrial protein import"
Lalb_09559	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
Lalb_06284	16	Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-8853884;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-176407;Reactome: R-HSA-176408;Reactome: R-HSA-174184	"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Transcriptional Regulation by VENTX";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
Lalb_11148	42	MetaCyc: PWY-5136;KEGG: 00903+4.2.1.17;MetaCyc: PWY-6583;MetaCyc: PWY-7401;MetaCyc: PWY-7007;KEGG: 00592+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;MetaCyc: PWY-7779;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;MetaCyc: PWY-5177;MetaCyc: PWY-5789;MetaCyc: PWY-7094;KEGG: 00627+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;MetaCyc: PWY-7726;MetaCyc: PWY-6883;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-5109;MetaCyc: PWY-6863;MetaCyc: PWY-7606;MetaCyc: PWY-7778;MetaCyc: PWY-6945;MetaCyc: PWY-7216;MetaCyc: PWY-1361;KEGG: 00410+4.2.1.17;MetaCyc: PWY-6435	"Fatty acid beta-oxidation II (plant peroxisome)";"Limonene and pinene degradation";"Pyruvate fermentation to butanol I";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Geraniol degradation";"Phenylalanine metabolism";"Valine, leucine and isoleucine degradation";"Toluene degradation";"Fatty acid elongation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Methyl tert-butyl ether degradation";"Fatty acid degradation";"Androstenedione degradation";"Caprolactam degradation";"Fatty acid degradation";"Spodoptera littoralis pheromone biosynthesis";"Tryptophan metabolism";"Benzoate degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Glutaryl-coa degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid salvage";"Aminobenzoate degradation";"Lysine degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Pyruvate fermentation to butanol II (engineered)";"Carbon fixation pathways in prokaryotes";"Butanoate metabolism";"Butanoate metabolism";"Propanoate metabolism";"Fermentation to 2-methylbutanoate";"Pyruvate fermentation to hexanol (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"2-methylpropene degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Benzoyl-coa degradation I (aerobic)";"beta-Alanine metabolism";"4-hydroxybenzoate biosynthesis III (plants)"
Lalb_08785	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
Lalb_01862	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
Lalb_07065	4	KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism"
Lalb_08697	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
Lalb_12594	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
Lalb_05833	8	KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1	"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Glycolysis";"Streptomycin biosynthesis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis"
Lalb_09249	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_02552	5	Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-9029558;Reactome: R-HSA-199220	"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism"
Lalb_05793	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
Lalb_06232	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
Lalb_06093	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
Lalb_02505	27	Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379	"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"snRNP Assembly";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"HCMV Late Events"
Lalb_13674	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
Lalb_04937	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
Lalb_07908	1	Reactome: R-HSA-8876725	"Protein methylation"
Lalb_02210	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
Lalb_13744	1	Reactome: R-HSA-176974	"Unwinding of DNA"
Lalb_11375	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
Lalb_05019	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
Lalb_12593	18	KEGG: 00640+1.8.1.4;KEGG: 00620+1.8.1.4;MetaCyc: PWY-5084;KEGG: 00260+1.8.1.4;Reactome: R-HSA-70895;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;KEGG: 00310+1.8.1.4;Reactome: R-HSA-6783984;Reactome: R-HSA-389661;KEGG: 00380+1.8.1.4;Reactome: R-HSA-70268;KEGG: 00010+1.8.1.4;KEGG: 00020+1.8.1.4;MetaCyc: PWY-5046;Reactome: R-HSA-71403;KEGG: 00280+1.8.1.4;Reactome: R-HSA-71064	"Propanoate metabolism";"Pyruvate metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glycine, serine and threonine metabolism";"Branched-chain amino acid catabolism";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Lysine degradation";"Glycine degradation";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Citric acid cycle (TCA cycle)";"Valine, leucine and isoleucine degradation";"Lysine catabolism"
Lalb_02211	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
Lalb_14281	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
Lalb_02148	9	Reactome: R-HSA-2022928;Reactome: R-HSA-1971475;Reactome: R-HSA-4420332;Reactome: R-HSA-975634;Reactome: R-HSA-2024096;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-3560783	"HS-GAG biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Retinoid metabolism and transport";"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type"
Lalb_06042	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
Lalb_12848	8	Reactome: R-HSA-2151209;Reactome: R-HSA-1632852;Reactome: R-HSA-9613354;Reactome: R-HSA-5628897;Reactome: R-HSA-9619483;Reactome: R-HSA-380972;Reactome: R-HSA-1445148;Reactome: R-HSA-6804756	"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Macroautophagy";"Lipophagy";"TP53 Regulates Metabolic Genes";"Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation"
Lalb_13127	14	KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;MetaCyc: PWY-6803;MetaCyc: PWY-7409;Reactome: R-HSA-975634;MetaCyc: PWY-8053;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4	"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Retinoid metabolism and transport";"Anandamide biosynthesis II";"Plasmalogen degradation";"Arachidonic acid metabolism"
Lalb_08933	7	MetaCyc: PWY-4984;Reactome: R-HSA-70635;KEGG: 00330+3.5.3.1;MetaCyc: PWY-46;MetaCyc: PWY-31;MetaCyc: PWY-6922;KEGG: 00220+3.5.3.1	"Urea cycle";"Urea cycle";"Arginine and proline metabolism";"Putrescine biosynthesis III";"Canavanine degradation";"L-Ndelta-acetylornithine biosynthesis";"Arginine biosynthesis"
Lalb_04847	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
Lalb_01565	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_10481	13	Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-1799339	"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane"
Lalb_02257	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
Lalb_03337	5	MetaCyc: PWY-7791;MetaCyc: PWY-5686;Reactome: R-HSA-500753;MetaCyc: PWY-7790;KEGG: 00240+4.1.1.23	"UMP biosynthesis III";"UMP biosynthesis I";"Pyrimidine biosynthesis";"UMP biosynthesis II";"Pyrimidine metabolism"
Lalb_02059	4	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis";"Pre-NOTCH Processing in Golgi"
Lalb_08196	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes"
Lalb_01435	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
Lalb_00285	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER"
Lalb_02069	2	Reactome: R-HSA-2514853;Reactome: R-HSA-2299718	"Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes"
Lalb_02642	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
Lalb_00139	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
Lalb_01654	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
Lalb_11439	1	Reactome: R-HSA-189200	"Cellular hexose transport"
Lalb_09922	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
Lalb_00451	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
Lalb_05472	10	Reactome: R-HSA-400206;Reactome: R-HSA-9022702;Reactome: R-HSA-9615017;Reactome: R-HSA-9022699;Reactome: R-HSA-8936459;Reactome: R-HSA-3899300;Reactome: R-HSA-983231;Reactome: R-HSA-9022692;Reactome: R-HSA-9022538;Reactome: R-HSA-427413	"Regulation of lipid metabolism by PPARalpha";"MECP2 regulates transcription of neuronal ligands";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"MECP2 regulates neuronal receptors and channels";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"SUMOylation of transcription cofactors";"Factors involved in megakaryocyte development and platelet production";"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to 5mC-DNA";"NoRC negatively regulates rRNA expression"
Lalb_02870	1	Reactome: R-HSA-3295583	"TRP channels"
Lalb_01607	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
Lalb_01402	2	Reactome: R-HSA-204626;MetaCyc: PWY-5905	"Hypusine synthesis from eIF5A-lysine";"Hypusine biosynthesis"
Lalb_10195	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
Lalb_14601	5	Reactome: R-HSA-500753;MetaCyc: PWY-5686;MetaCyc: PWY-7790;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7791	"Pyrimidine biosynthesis";"UMP biosynthesis I";"UMP biosynthesis II";"Pyrimidine metabolism";"UMP biosynthesis III"
Lalb_10293	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
Lalb_04567	6	Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444	"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
Lalb_02732	1	Reactome: R-HSA-5689603	"UCH proteinases"
Lalb_01420	1	Reactome: R-HSA-1632852	"Macroautophagy"
Lalb_00620	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
Lalb_13196	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
Lalb_11290	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-202433	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Generation of second messenger molecules"
Lalb_07573	5	KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855	"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)"
Lalb_09098	1	Reactome: R-HSA-8951664	"Neddylation"
Lalb_09854	4	Reactome: R-HSA-389661;Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-77289	"Glyoxylate metabolism and glycine degradation";"Complex I biogenesis";"Respiratory electron transport";"Mitochondrial Fatty Acid Beta-Oxidation"
Lalb_06043	5	Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-72163	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway"
Lalb_03207	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
Lalb_13277	4	Reactome: R-HSA-4719360;Reactome: R-HSA-162699;Reactome: R-HSA-4719377;Reactome: R-HSA-4717374	"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM1 causes DPM1-CDG (CDG-1e)"
Lalb_03499	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
Lalb_10234	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
Lalb_00659	3	Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3	"Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism"
Lalb_10338	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
Lalb_00422	16	Reactome: R-HSA-196025;Reactome: R-HSA-2132295;Reactome: R-HSA-8856825;Reactome: R-HSA-164939;Reactome: R-HSA-8964038;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665;Reactome: R-HSA-416993;Reactome: R-HSA-182218;Reactome: R-HSA-190873;Reactome: R-HSA-177504;Reactome: R-HSA-8856828;Reactome: R-HSA-167590;Reactome: R-HSA-5099900;Reactome: R-HSA-437239;Reactome: R-HSA-8866427	"Formation of annular gap junctions";"MHC class II antigen presentation";"Cargo recognition for clathrin-mediated endocytosis";"Nef mediated downregulation of CD28 cell surface expression";"LDL clearance";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells";"Trafficking of GluR2-containing AMPA receptors";"Nef Mediated CD8 Down-regulation";"Gap junction degradation";"Retrograde neurotrophin signalling";"Clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"WNT5A-dependent internalization of FZD4";"Recycling pathway of L1";"VLDLR internalisation and degradation"
Lalb_02543	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
Lalb_13078	57	Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-6798695;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236	"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Neutrophil degranulation";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
Lalb_07364	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
Lalb_01030	5	MetaCyc: PWY-5083;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268	"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
Lalb_00356	13	Reactome: R-HSA-416572;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3928663;KEGG: 05163+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-416482;Reactome: R-HSA-3928662;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5627117	"Sema4D induced cell migration and growth-cone collapse";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"EPHA-mediated growth cone collapse";"Human cytomegalovirus infection";"VEGFA-VEGFR2 Pathway";"G alpha (12/13) signalling events";"EPHB-mediated forward signaling";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"RHO GTPases Activate ROCKs"
Lalb_00624	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
Lalb_08388	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
Lalb_12546	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
Lalb_14034	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
Lalb_09363	5	KEGG: 00983+2.4.2.3;Reactome: R-HSA-73621;MetaCyc: PWY-5532;Reactome: R-HSA-73614;KEGG: 00240+2.4.2.3	"Drug metabolism - other enzymes";"Pyrimidine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine salvage";"Pyrimidine metabolism"
Lalb_01131	3	KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis"
Lalb_09081	5	Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5689901;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565	"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Metalloprotease DUBs";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
Lalb_14061	29	Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-6782210;Reactome: R-HSA-73863;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-5696395;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-6781827;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-167162;Reactome: R-HSA-427413	"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"RNA Polymerase II HIV Promoter Escape";"NoRC negatively regulates rRNA expression"
Lalb_05326	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
Lalb_12170	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
Lalb_05847	4	KEGG: 00908+2.5.1.75;Reactome: R-HSA-6782315;Reactome: R-HSA-6787450;MetaCyc: PWY-2781	"Zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion";"Cis-zeatin biosynthesis"
Lalb_00902	6	Reactome: R-HSA-9028731;Reactome: R-HSA-5673001;Reactome: R-HSA-5654700;Reactome: R-HSA-5654712;Reactome: R-HSA-5654706;Reactome: R-HSA-5654693	"Activated NTRK2 signals through FRS2 and FRS3";"RAF/MAP kinase cascade";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR1 signaling"
Lalb_06982	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
Lalb_11124	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
Lalb_13451	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
Lalb_06935	5	MetaCyc: PWY-6692;KEGG: 00190+7.1.1.8;MetaCyc: PWY-3781;MetaCyc: PWY-7082;MetaCyc: PWY-7279	"Fe(II) oxidation";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration II (cytochrome c) (yeast)"
Lalb_11443	8	KEGG: 00950+1.14.16.2;Reactome: R-HSA-209905;MetaCyc: PWY-3581;MetaCyc: PWY-5394;MetaCyc: PWY-5049;MetaCyc: PWY-6133;KEGG: 00790+1.14.16.2;KEGG: 00350+1.14.16.2	"Isoquinoline alkaloid biosynthesis";"Catecholamine biosynthesis";"(S)-reticuline biosynthesis I";"Betalamic acid biosynthesis";"Rosmarinic acid biosynthesis II";"(S)-reticuline biosynthesis II";"Folate biosynthesis";"Tyrosine metabolism"
Lalb_07830	6	MetaCyc: PWY-7077;MetaCyc: PWY-7395;KEGG: 00052+3.5.1.25;Reactome: R-HSA-446210;MetaCyc: PWY-6906;KEGG: 00520+3.5.1.25	"N-acetyl-D-galactosamine degradation";"D-galactosamine and N-acetyl-D-galactosamine degradation";"Galactose metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism"
Lalb_09741	56	Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-174113;Reactome: R-HSA-5610785;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-8939902	"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF-beta-TrCP mediated degradation of Emi1";"GLI3 is processed to GLI3R by the proteasome";"Interleukin-1 signaling";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Regulation of RAS by GAPs";"Degradation of AXIN";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity"
Lalb_10438	12	MetaCyc: PWY-5857;MetaCyc: PWY-5855;MetaCyc: PWY-5870;MetaCyc: PWY-5873;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5856;Reactome: R-HSA-2142789;MetaCyc: PWY-7233;MetaCyc: PWY-5872;MetaCyc: PWY-5871;MetaCyc: PWY-6708;MetaCyc: PWY-7230	"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)"
Lalb_02774	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
Lalb_08829	57	Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-174154;Reactome: R-HSA-6798695;Reactome: R-HSA-211733;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-382556	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Degradation of AXIN";"Regulation of RAS by GAPs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Hedgehog 'on' state";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"APC/C:Cdc20 mediated degradation of Securin";"Neutrophil degranulation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport"
Lalb_04018	2	Reactome: R-HSA-181429;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
Lalb_00657	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
Lalb_10568	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
Lalb_04754	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
Lalb_06440	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
Lalb_06010	3	Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
Lalb_00951	4	Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-69205	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA";"G1/S-Specific Transcription"
Lalb_03812	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
Lalb_04203	17	KEGG: 00620+1.1.1.37;MetaCyc: PWY-6728;KEGG: 00680+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-6969;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-7115;KEGG: 00020+1.1.1.37;KEGG: 00710+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-8086;MetaCyc: PWY-5392;MetaCyc: PWY-561;MetaCyc: PWY-1622	"Pyruvate metabolism";"Methylaspartate cycle";"Methane metabolism";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Cysteine and methionine metabolism";"TCA cycle II (plants and fungi)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Citrate cycle (TCA cycle)";"Carbon fixation in photosynthetic organisms";"Glyoxylate and dicarboxylate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Reductive TCA cycle II";"Superpathway of glyoxylate cycle and fatty acid degradation";"Formaldehyde assimilation I (serine pathway)"
Lalb_11288	8	KEGG: 00220+4.3.2.1;MetaCyc: PWY-4984;MetaCyc: PWY-7400;MetaCyc: PWY-5;KEGG: 00250+4.3.2.1;Reactome: R-HSA-70635;MetaCyc: PWY-4983;MetaCyc: PWY-5154	"Arginine biosynthesis";"Urea cycle";"L-arginine biosynthesis IV (archaebacteria)";"Canavanine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Urea cycle";"Nitric oxide biosynthesis II (mammals)";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)"
Lalb_02593	5	Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-6814122	"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
Lalb_12424	17	Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-174417;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-5656169;Reactome: R-HSA-174437;Reactome: R-HSA-5358606;Reactome: R-HSA-174414;Reactome: R-HSA-110314;Reactome: R-HSA-69166;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-5358565	"Dual Incision in GG-NER";"Dual incision in TC-NER";"Telomere C-strand (Lagging Strand) Synthesis";"Processive synthesis on the lagging strand";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processive synthesis on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
Lalb_03042	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
Lalb_10125	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
Lalb_01706	6	Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72649	"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation"
Lalb_01281	27	Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-159230	"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"snRNP Assembly";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA"
Lalb_02587	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
Lalb_09180	2	Reactome: R-HSA-1912399;KEGG: 00514+2.4.1.221	"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Other types of O-glycan biosynthesis"
Lalb_13779	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
Lalb_05169	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
Lalb_10814	3	MetaCyc: PWY-7511;Reactome: R-HSA-349425;Reactome: R-HSA-8951664	"Protein ubiquitination";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation"
Lalb_02191	2	KEGG: 00230+4.6.1.1;Reactome: R-HSA-196819	"Purine metabolism";"Vitamin B1 (thiamin) metabolism"
Lalb_00193	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
Lalb_09313	8	Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-8943724	"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Macroautophagy";"HSF1-dependent transactivation";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription"
Lalb_12708	12	KEGG: 00261+2.7.7.4;KEGG: 00450+2.7.7.4;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5278;KEGG: 00920+2.7.7.4;KEGG: 00230+2.7.1.25;KEGG: 00920+2.7.1.25;MetaCyc: PWY-6932;MetaCyc: PWY-5340;MetaCyc: PWY-6683;Reactome: R-HSA-174362;Reactome: R-HSA-2408550	"Monobactam biosynthesis";"Selenocompound metabolism";"Purine metabolism";"Sulfite oxidation III";"Sulfur metabolism";"Purine metabolism";"Sulfur metabolism";"Selenate reduction";"Sulfate activation for sulfonation";"Assimilatory sulfate reduction III";"Transport and synthesis of PAPS";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se"
Lalb_10660	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_10954	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
Lalb_09107	13	Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
Lalb_03801	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
Lalb_01858	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
Lalb_03740	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
Lalb_02261	16	Reactome: R-HSA-912526;Reactome: R-HSA-388841;Reactome: R-HSA-9009391;Reactome: R-HSA-194840;Reactome: R-HSA-8853659;Reactome: R-HSA-416476;Reactome: R-HSA-6811558;Reactome: R-HSA-1266695;Reactome: R-HSA-389357;Reactome: R-HSA-1660499;Reactome: R-HSA-512988;Reactome: R-HSA-114604;Reactome: R-HSA-1257604;Reactome: R-HSA-912631;Reactome: R-HSA-2219530;Reactome: R-HSA-1433557	"Interleukin receptor SHC signaling";"Costimulation by the CD28 family";"Extra-nuclear estrogen signaling";"Rho GTPase cycle";"RET signaling";"G alpha (q) signalling events";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Interleukin-7 signaling";"CD28 dependent PI3K/Akt signaling";"Synthesis of PIPs at the plasma membrane";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"GPVI-mediated activation cascade";"PIP3 activates AKT signaling";"Regulation of signaling by CBL";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by SCF-KIT"
Lalb_05635	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
Lalb_04204	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
Lalb_13190	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
Lalb_00425	4	Reactome: R-HSA-947581;MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7;Reactome: R-HSA-1362409	"Molybdenum cofactor biosynthesis";"[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism";"Mitochondrial iron-sulfur cluster biogenesis"
Lalb_00737	2	Reactome: R-HSA-5689880;Reactome: R-HSA-8949215	"Ub-specific processing proteases";"Mitochondrial calcium ion transport"
Lalb_02174	1	Reactome: R-HSA-350562	"Regulation of ornithine decarboxylase (ODC)"
Lalb_01463	6	MetaCyc: PWY-5097;MetaCyc: PWY-8088;MetaCyc: PWY-2942;KEGG: 00261+4.3.3.7;KEGG: 00300+4.3.3.7;MetaCyc: PWY-2941	"L-lysine biosynthesis VI";"Dipicolinate biosynthesis";"L-lysine biosynthesis III";"Monobactam biosynthesis";"Lysine biosynthesis";"L-lysine biosynthesis II"
Lalb_07938	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
Lalb_03903	18	Reactome: R-HSA-499943;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7197;MetaCyc: PWY-7187;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7210;MetaCyc: PWY-7205;MetaCyc: PWY-7220;MetaCyc: PWY-7184;MetaCyc: PWY-7226;MetaCyc: PWY-6545;MetaCyc: PWY-7227	"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis"
Lalb_04619	5	Reactome: R-HSA-209560;Reactome: R-HSA-209543;Reactome: R-HSA-9020702;Reactome: R-HSA-205043;Reactome: R-HSA-5205685	"NF-kB is activated and signals survival";"p75NTR recruits signalling complexes";"Interleukin-1 signaling";"NRIF signals cell death from the nucleus";"Pink/Parkin Mediated Mitophagy"
Lalb_11284	12	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-6804756;Reactome: R-HSA-167290	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Regulation of TP53 Activity through Phosphorylation";"Pausing and recovery of HIV elongation"
Lalb_09189	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
Lalb_01947	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
Lalb_04532	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
Lalb_12077	3	Reactome: R-HSA-8853383;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.25	"Lysosomal oligosaccharide catabolism";"Neutrophil degranulation";"Other glycan degradation"
Lalb_05808	24	Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-5626467	"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"Cilium Assembly";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Recycling pathway of L1";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs"
Lalb_09936	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
Lalb_11272	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
Lalb_01056	1	Reactome: R-HSA-71384	"Ethanol oxidation"
Lalb_00891	16	Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
Lalb_08708	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
Lalb_03015	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
Lalb_05360	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
Lalb_02084	7	MetaCyc: PWY-4702;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;Reactome: R-HSA-1855183;MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25	"Phytate degradation I";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis"
Lalb_13729	5	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing"
Lalb_03208	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
Lalb_12877	6	Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex"
Lalb_06930	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
Lalb_00358	13	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-416482;Reactome: R-HSA-3928662;Reactome: R-HSA-4420097;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3928663;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5627117;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Sema4D induced cell migration and growth-cone collapse";"G alpha (12/13) signalling events";"EPHB-mediated forward signaling";"VEGFA-VEGFR2 Pathway";"Human cytomegalovirus infection";"EPHA-mediated growth cone collapse";"Thermogenesis";"RHO GTPases Activate ROCKs";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection"
Lalb_03311	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
Lalb_12580	4	Reactome: R-HSA-4549349;KEGG: 00513+2.4.1.257+2.4.1.132;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.257+2.4.1.132	"Defective ALG2 causes ALG2-CDG (CDG-1i)";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
Lalb_14347	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
Lalb_01507	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
Lalb_09621	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
Lalb_03426	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
Lalb_14160	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
Lalb_05725	1	MetaCyc: PWY-7511	"Protein ubiquitination"
Lalb_01618	3	MetaCyc: PWY-5686;KEGG: 00240+1.3.5.2;Reactome: R-HSA-500753	"UMP biosynthesis I";"Pyrimidine metabolism";"Pyrimidine biosynthesis"
Lalb_09787	3	Reactome: R-HSA-202427;Reactome: R-HSA-6798695;Reactome: R-HSA-6807004	"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation";"Negative regulation of MET activity"
Lalb_14451	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_12658	14	MetaCyc: PWY-5981;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-7782;MetaCyc: PWY-8051;MetaCyc: PWY-7589;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-6453;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8053;Reactome: R-HSA-1483166	"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Synthesis of PA"
Lalb_12070	1	Reactome: R-HSA-8951664	"Neddylation"
Lalb_09744	3	Reactome: R-HSA-110314;Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"Recognition of DNA damage by PCNA-containing replication complex";"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
Lalb_00310	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
Lalb_10274	18	KEGG: 00360+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00400+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00401+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00220+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-7383;KEGG: 00270+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00330+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00250+2.6.1.1	"Phenylalanine metabolism";"(R)-cysteate degradation";"Carbon fixation in photosynthetic organisms";"Coenzyme M biosynthesis II";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Novobiocin biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Arginine biosynthesis";"Sulfolactate degradation III";"Anaerobic energy metabolism (invertebrates, cytosol)";"Cysteine and methionine metabolism";"Isoquinoline alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Arginine and proline metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Tyrosine metabolism";"Alanine, aspartate and glutamate metabolism"
Lalb_06439	2	Reactome: R-HSA-156588;Reactome: R-HSA-71403	"Glucuronidation";"Citric acid cycle (TCA cycle)"
Lalb_12548	4	Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402	"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex"
Lalb_07553	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
Lalb_00155	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
Lalb_04137	56	Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-382556	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Regulation of RAS by GAPs";"Degradation of AXIN";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Hedgehog 'on' state";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport"
Lalb_01161	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
Lalb_12631	3	Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-1268020	"Respiratory electron transport";"Complex I biogenesis";"Mitochondrial protein import"
Lalb_00666	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
Lalb_03865	17	MetaCyc: PWY-6728;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-6969;KEGG: 00270+1.1.1.37;KEGG: 00720+1.1.1.37;KEGG: 00680+1.1.1.37;KEGG: 00020+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-5690;MetaCyc: PWY-1622;MetaCyc: PWY-5392;MetaCyc: PWY-561;MetaCyc: PWY-8086;MetaCyc: PWY-7383;KEGG: 00630+1.1.1.37;KEGG: 00710+1.1.1.37	"Methylaspartate cycle";"Pyruvate metabolism";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Cysteine and methionine metabolism";"Carbon fixation pathways in prokaryotes";"Methane metabolism";"Citrate cycle (TCA cycle)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"TCA cycle II (plants and fungi)";"Formaldehyde assimilation I (serine pathway)";"Reductive TCA cycle II";"Superpathway of glyoxylate cycle and fatty acid degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation in photosynthetic organisms"
Lalb_03591	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
Lalb_06145	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
Lalb_05214	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
Lalb_01589	6	Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-2173788;Reactome: R-HSA-8863795;Reactome: R-HSA-8939902;MetaCyc: PWY-7511	"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of TGF-beta receptor signaling";"Downregulation of ERBB2 signaling";"Regulation of RUNX2 expression and activity";"Protein ubiquitination"
Lalb_08178	1	Reactome: R-HSA-912446	"Meiotic recombination"
Lalb_11394	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_00293	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
Lalb_01176	1	Reactome: R-HSA-400253	"Circadian Clock"
Lalb_11174	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
Lalb_02126	16	Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-8853884;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-176412	"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Transcriptional Regulation by VENTX";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Phosphorylation of the APC/C"
Lalb_11978	17	Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-6790901;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975957	"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
Lalb_02677	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
Lalb_03818	2	Reactome: R-HSA-5654726;Reactome: R-HSA-190373	"Negative regulation of FGFR1 signaling";"FGFR1c ligand binding and activation"
Lalb_05043	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
Lalb_02896	8	Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-8953750;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554	"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Transcriptional Regulation by E2F6";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
Lalb_09640	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
Lalb_00848	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
Lalb_09595	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
Lalb_07911	7	Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-1362277	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"G1/S-Specific Transcription";"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex"
Lalb_02581	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
Lalb_03556	2	Reactome: R-HSA-5689880;Reactome: R-HSA-8949215	"Ub-specific processing proteases";"Mitochondrial calcium ion transport"
Lalb_11424	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
Lalb_02856	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
Lalb_09588	4	Reactome: R-HSA-9020702;Reactome: R-HSA-937039;MetaCyc: PWY-7511;Reactome: R-HSA-975144	"Interleukin-1 signaling";"IRAK1 recruits IKK complex";"Protein ubiquitination";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"
Lalb_00226	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
Lalb_04451	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_03564	16	Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72649	"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation"
Lalb_08069	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
Lalb_04648	4	Reactome: R-HSA-212300;Reactome: R-HSA-5334118;Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37	"PRC2 methylates histones and DNA";"DNA methylation";"SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism"
Lalb_04191	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
Lalb_13751	1	Reactome: R-HSA-390651	"Dopamine receptors"
Lalb_12616	3	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.19	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis"
Lalb_01412	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_06014	6	Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-6791226	"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_05131	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
Lalb_07817	2	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
Lalb_05816	1	Reactome: R-HSA-5657655	"MGMT-mediated DNA damage reversal"
Lalb_11360	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689896	"Ub-specific processing proteases";"Ovarian tumor domain proteases"
Lalb_11371	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
Lalb_06561	2	MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism"
Lalb_12044	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
Lalb_11165	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
Lalb_05629	57	Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-6798695;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-9020702;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-174113	"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Degradation of AXIN";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neutrophil degranulation";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Interleukin-1 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1"
Lalb_08987	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
Lalb_13928	7	Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-141444	"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
Lalb_10999	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
Lalb_05892	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
Lalb_10485	6	Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216	"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization"
Lalb_03326	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
Lalb_11695	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
Lalb_14082	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
Lalb_08419	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
Lalb_08713	16	Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72695	"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex"
Lalb_07344	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
Lalb_11468	1	Reactome: R-HSA-6798163	"Choline catabolism"
Lalb_05915	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
Lalb_03806	3	Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427	"Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains"
Lalb_13743	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
Lalb_10977	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
Lalb_07705	4	Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
Lalb_04883	3	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation"
Lalb_04060	9	KEGG: 00401+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00400+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00270+2.6.1.5;KEGG: 00950+2.6.1.5	"Novobiocin biosynthesis";"Phenylalanine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Tyrosine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tyrosine catabolism";"Cysteine and methionine metabolism";"Isoquinoline alkaloid biosynthesis"
Lalb_10443	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
Lalb_09557	1	Reactome: R-HSA-8951664	"Neddylation"
Lalb_04896	31	MetaCyc: PWY-7664;MetaCyc: PWY-5971;MetaCyc: PWY-6282;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5973;MetaCyc: PWY-6113;MetaCyc: PWY-7723;MetaCyc: PWY-8047;MetaCyc: PWY-5989;MetaCyc: PWY-4381;Reactome: R-HSA-2426168;MetaCyc: PWY-5147;MetaCyc: PWY-7663;MetaCyc: PWY-5966-1;Reactome: R-HSA-199220;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-8012;MetaCyc: PWY-7388;MetaCyc: PWYG-321;Reactome: R-HSA-75105;MetaCyc: PWY-7746;Reactome: R-HSA-163765;MetaCyc: PWY-6799;MetaCyc: PWY-5366;MetaCyc: PWY-8049;MetaCyc: PWY-5367;MetaCyc: PWY-5142;MetaCyc: PWY-7858;MetaCyc: PWY-6519;MetaCyc: PWY-5994;Reactome: R-HSA-9029558	"Oleate biosynthesis IV (anaerobic)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Biotin metabolism";"Cis-vaccenate biosynthesis";"Superpathway of mycolate biosynthesis";"Bacterial bioluminescence";"Bryostatin biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"Oleate biosynthesis I (plants)";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"Fatty acid biosynthesis";"Mupirocin biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"";"Fatty acyl-CoA biosynthesis";"Mycobacterial sulfolipid biosynthesis";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (plant mitochondria)";"Palmitoleate biosynthesis II (plants and bacteria)";"Pederin biosynthesis";"Petroselinate biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"(5Z)-dodecenoate biosynthesis II";"8-amino-7-oxononanoate biosynthesis I";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis"
Lalb_08774	16	Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
Lalb_08204	7	Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-114608;Reactome: R-HSA-140837;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (i) signalling events";"Platelet degranulation";"Intrinsic Pathway of Fibrin Clot Formation";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"G alpha (q) signalling events"
Lalb_04765	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
Lalb_00271	5	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288	"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1"
Lalb_04130	14	MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-6433	"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)"
Lalb_12682	10	Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-3214847;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167162	"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HATs acetylate histones";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape"
Lalb_02869	10	MetaCyc: PWY-5340;MetaCyc: PWY-6683;Reactome: R-HSA-174362;Reactome: R-HSA-2408550;KEGG: 00261+2.7.7.4;KEGG: 00230+2.7.7.4;KEGG: 00450+2.7.7.4;MetaCyc: PWY-5278;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6932	"Sulfate activation for sulfonation";"Assimilatory sulfate reduction III";"Transport and synthesis of PAPS";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Monobactam biosynthesis";"Purine metabolism";"Selenocompound metabolism";"Sulfite oxidation III";"Sulfur metabolism";"Selenate reduction"
Lalb_01216	17	Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
Lalb_10987	4	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates"
Lalb_14149	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
Lalb_13917	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
Lalb_10149	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
Lalb_07040	7	Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693607	"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends"
Lalb_04131	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_06087	2	KEGG: 00860+4.99.1.1;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
Lalb_11887	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
Lalb_07036	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
Lalb_07602	5	Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-3232118;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571	"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"SUMOylation of transcription factors";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)"
Lalb_02083	6	Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-176974	"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Unwinding of DNA"
Lalb_09833	13	KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2022857;Reactome: R-HSA-2206308;Reactome: R-HSA-4341670;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23;Reactome: R-HSA-1660662;KEGG: 00052+3.2.1.23;Reactome: R-HSA-4085001;Reactome: R-HSA-6798695	"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Keratan sulfate degradation";"MPS IV - Morquio syndrome B";"Defective NEU1 causes sialidosis";"Other glycan degradation";"HS-GAG degradation";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Galactose metabolism";"Sialic acid metabolism";"Neutrophil degranulation"
Lalb_01583	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_07701	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
Lalb_02087	7	Reactome: R-HSA-1855183;MetaCyc: PWY-2301;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-4702;MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25	"Synthesis of IP2, IP, and Ins in the cytosol";"Myo-inositol biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Phytate degradation I";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis"
Lalb_04821	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
Lalb_11798	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
Lalb_13278	3	Reactome: R-HSA-5689877;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395	"Josephin domain DUBs";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER"
Lalb_00284	2	MetaCyc: PWY-5381;KEGG: 00760+2.7.1.173+2.7.1.22	"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism"
Lalb_08461	3	Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394	"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER"
Lalb_00630	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
Lalb_09645	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
Lalb_13386	2	KEGG: 00970+6.1.1.2;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
Lalb_06143	13	Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72689	"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits"
Lalb_11645	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
Lalb_04673	6	Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
Lalb_11224	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_03787	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
Lalb_07239	1	Reactome: R-HSA-8951664	"Neddylation"
Lalb_11513	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
Lalb_04474	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
Lalb_00941	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6798695	"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation"
Lalb_08366	6	Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-450604	"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA"
Lalb_06607	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
Lalb_07114	3	KEGG: 00860+1.16.3.1;Reactome: R-HSA-1362409;Reactome: R-HSA-1268020	"Porphyrin and chlorophyll metabolism";"Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import"
Lalb_02730	1	Reactome: R-HSA-5689603	"UCH proteinases"
Lalb_00368	2	Reactome: R-HSA-2151201;Reactome: R-HSA-6793080	"Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion"
Lalb_09778	32	Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-77075;Reactome: R-HSA-167290;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-8851708;Reactome: R-HSA-112382;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-167162;Reactome: R-HSA-168325;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-6803529;Reactome: R-HSA-72203;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-76042;Reactome: R-HSA-72163	"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"Estrogen-dependent gene expression";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Signaling by FGFR2 IIIa TM";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II HIV Promoter Escape";"Viral Messenger RNA Synthesis";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"FGFR2 alternative splicing";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Splicing - Major Pathway"
Lalb_06662	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
Lalb_01269	6	Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994	"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
Lalb_07132	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
Lalb_12971	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
Lalb_14035	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
Lalb_13671	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_10474	26	Reactome: R-HSA-983189;Reactome: R-HSA-5626467;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-389960;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-389977	"Kinesins";"RHO GTPases activate IQGAPs";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Formation of tubulin folding intermediates by CCT/TriC";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Post-chaperonin tubulin folding pathway"
Lalb_12041	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
Lalb_04911	4	Reactome: R-HSA-5689880;Reactome: R-HSA-111465;Reactome: R-HSA-176187;Reactome: R-HSA-5693607	"Ub-specific processing proteases";"Apoptotic cleavage of cellular proteins";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends"
Lalb_03401	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
Lalb_03945	1	Reactome: R-HSA-8949613	"Cristae formation"
Lalb_11573	11	Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport";"Recruitment of mitotic centrosome proteins and complexes"
Lalb_04982	5	Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558;Reactome: R-HSA-163765;Reactome: R-HSA-199220	"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism"
Lalb_03126	5	Reactome: R-HSA-2219530;Reactome: R-HSA-109704;Reactome: R-HSA-5673001;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604	"Constitutive Signaling by Aberrant PI3K in Cancer";"PI3K Cascade";"RAF/MAP kinase cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling"
Lalb_03585	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
Lalb_07119	10	Reactome: R-HSA-5635838;Reactome: R-HSA-1445148;Reactome: R-HSA-373080;Reactome: R-HSA-5362798;Reactome: R-HSA-5620916;Reactome: R-HSA-5632684;Reactome: R-HSA-5658034;Reactome: R-HSA-5358346;Reactome: R-HSA-264876;Reactome: R-HSA-5632681	"Activation of SMO";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Class B/2 (Secretin family receptors)";"Release of Hh-Np from the secreting cell";"VxPx cargo-targeting to cilium";"Hedgehog 'on' state";"HHAT G278V abrogates palmitoylation of Hh-Np";"Hedgehog ligand biogenesis";"Insulin processing";"Ligand-receptor interactions"
Lalb_06170	1	MetaCyc: PWY-7511	"Protein ubiquitination"
Lalb_10110	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
Lalb_00946	3	MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689	"Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I"
Lalb_10162	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
Lalb_06282	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
Lalb_08306	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
Lalb_04957	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
Lalb_06745	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
Lalb_06100	14	Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7035	"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis"
Lalb_05108	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
Lalb_00351	16	Reactome: R-HSA-983168;Reactome: R-HSA-167246;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-167287;Reactome: R-HSA-180585;Reactome: R-HSA-167243;Reactome: R-HSA-9010553;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167152	"Antigen processing: Ubiquitination & Proteasome degradation";"Tat-mediated elongation of the HIV-1 transcript";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"HIV elongation arrest and recovery";"Vif-mediated degradation of APOBEC3G";"Tat-mediated HIV elongation arrest and recovery";"Regulation of expression of SLITs and ROBOs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat"
Lalb_14384	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
Lalb_13936	37	Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-3108214;Reactome: R-HSA-141444;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-2467813;Reactome: R-HSA-983170;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-204005;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-2500257;Reactome: R-HSA-9639288	"HCMV Late Events";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"SUMOylation of DNA damage response and repair proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Separation of Sister Chromatids";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"COPII-mediated vesicle transport";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Resolution of Sister Chromatid Cohesion";"Amino acids regulate mTORC1"
Lalb_09512	2	Reactome: R-HSA-6794361;Reactome: R-HSA-216083	"Neurexins and neuroligins";"Integrin cell surface interactions"
Lalb_12873	2	Reactome: R-HSA-190373;Reactome: R-HSA-5654726	"FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling"
Lalb_06565	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
Lalb_03626	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
Lalb_05110	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
Lalb_01311	1	Reactome: R-HSA-5689603	"UCH proteinases"
Lalb_08335	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
Lalb_08939	4	Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814	"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes"
Lalb_04592	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
Lalb_12166	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
Lalb_05408	5	Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
Lalb_00948	58	Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-6798695;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-8941858;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-5689901;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-69017;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neutrophil degranulation";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"Regulation of RUNX3 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Metalloprotease DUBs";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"Degradation of AXIN";"Regulation of RAS by GAPs";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"CDK-mediated phosphorylation and removal of Cdc6";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
Lalb_09089	16	Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-167243;Reactome: R-HSA-180585;Reactome: R-HSA-167287;Reactome: R-HSA-8951664;Reactome: R-HSA-167246;Reactome: R-HSA-983168	"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Tat-mediated HIV elongation arrest and recovery";"Vif-mediated degradation of APOBEC3G";"HIV elongation arrest and recovery";"Neddylation";"Tat-mediated elongation of the HIV-1 transcript";"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_02948	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
Lalb_03612	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
Lalb_00740	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
Lalb_02633	9	MetaCyc: PWY-5981;MetaCyc: PWY-7902;KEGG: 00564+1.1.1.94;KEGG: 00564+1.1.1.8;Reactome: R-HSA-1483166;MetaCyc: PWY-6118;MetaCyc: PWY-7385;MetaCyc: PWY-5667;MetaCyc: PWY-7411	"CDP-diacylglycerol biosynthesis III";"Glucosylglycerol biosynthesis";"Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"Synthesis of PA";"Glycerol-3-phosphate shuttle";"1,3-propanediol biosynthesis (engineered)";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)"
Lalb_13733	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
Lalb_01351	7	Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-606279	"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Deposition of new CENPA-containing nucleosomes at the centromere"
Lalb_08432	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5083627;Reactome: R-HSA-5173105	"Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation"
Lalb_01347	1	Reactome: R-HSA-1632852	"Macroautophagy"
Lalb_11008	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
Lalb_10451	1	Reactome: R-HSA-156588	"Glucuronidation"
Lalb_06842	14	MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-6598	"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis"
Lalb_06770	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
Lalb_08870	11	MetaCyc: PWY-5154;MetaCyc: PWY-5686;KEGG: 00250+6.3.5.5;KEGG: 00240+2.1.3.2;MetaCyc: PWY-7790;Reactome: R-HSA-500753;MetaCyc: PWY-7400;KEGG: 00250+2.1.3.2;KEGG: 00240+3.5.2.3;KEGG: 00240+6.3.5.5;MetaCyc: PWY-7791	"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"UMP biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"UMP biosynthesis II";"Pyrimidine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"Pyrimidine metabolism";"UMP biosynthesis III"
Lalb_06505	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
Lalb_08156	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
Lalb_07201	3	Reactome: R-HSA-5632928;Reactome: R-HSA-5632968;Reactome: R-HSA-5358565	"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
Lalb_11610	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_13342	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
Lalb_00989	12	Reactome: R-HSA-205043;Reactome: R-HSA-9013700;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-977225;Reactome: R-HSA-3928665;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-193692;Reactome: R-HSA-1251985;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507	"NRIF signals cell death from the nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"Regulated proteolysis of p75NTR";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
Lalb_11593	13	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6802948;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6802952;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Signaling by high-kinase activity BRAF mutants";"Human cytomegalovirus infection";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Thermogenesis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"Human papillomavirus infection";"Signaling by BRAF and RAF fusions";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
Lalb_01558	14	MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7602	"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
Lalb_05897	7	KEGG: 00240+2.7.4.14;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00983+2.7.4.14;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7176	"Pyrimidine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Drug metabolism - other enzymes";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis"
Lalb_10240	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
Lalb_01915	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
Lalb_05104	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
Lalb_07074	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
Lalb_09596	2	KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
Lalb_09626	2	Reactome: R-HSA-8876725;Reactome: R-HSA-611105	"Protein methylation";"Respiratory electron transport"
Lalb_03593	7	Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
Lalb_00360	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_06946	4	Reactome: R-HSA-4570464;Reactome: R-HSA-72203;Reactome: R-HSA-9610379;Reactome: R-HSA-72163	"SUMOylation of RNA binding proteins";"Processing of Capped Intron-Containing Pre-mRNA";"HCMV Late Events";"mRNA Splicing - Major Pathway"
Lalb_07748	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
Lalb_04671	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
Lalb_10701	10	Reactome: R-HSA-611105;Reactome: R-HSA-5628897;Reactome: R-HSA-3299685;Reactome: R-HSA-111464;Reactome: R-HSA-111463;Reactome: R-HSA-111459;Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-111457;Reactome: R-HSA-2151201	"Respiratory electron transport";"TP53 Regulates Metabolic Genes";"Detoxification of Reactive Oxygen Species";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC (DIABLO) binds to IAPs";"Activation of caspases through apoptosome-mediated cleavage";"Regulation of the apoptosome activity";"Formation of apoptosome";"Release of apoptotic factors from the mitochondria";"Transcriptional activation of mitochondrial biogenesis"
Lalb_04016	2	Reactome: R-HSA-181429;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
Lalb_07405	7	KEGG: 00562+2.7.1.67;Reactome: R-HSA-1660516;MetaCyc: PWY-6351;KEGG: 04070+2.7.1.67;Reactome: R-HSA-1660499;Reactome: R-HSA-1660514;MetaCyc: PWY-6352	"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the Golgi membrane";"3-phosphoinositide biosynthesis"
Lalb_02137	179	Reactome: R-HSA-1295596;Reactome: R-HSA-937041;Reactome: R-HSA-4641258;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-9013973;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-2559585;Reactome: R-HSA-2122947;Reactome: R-HSA-5205685;Reactome: R-HSA-1236974;Reactome: R-HSA-5357956;Reactome: R-HSA-5607764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-8849469;Reactome: R-HSA-4641263;Reactome: R-HSA-445989;Reactome: R-HSA-937072;Reactome: R-HSA-5607761;Reactome: R-HSA-936440;Reactome: R-HSA-2894862;Reactome: R-HSA-8866654;Reactome: R-HSA-937039;Reactome: R-HSA-5654727;Reactome: R-HSA-192823;Reactome: R-HSA-201681;Reactome: R-HSA-9637628;Reactome: R-HSA-69231;Reactome: R-HSA-5668541;Reactome: R-HSA-2559582;Reactome: R-HSA-9014325;Reactome: R-HSA-6804756;Reactome: R-HSA-195253;Reactome: R-HSA-5685942;Reactome: R-HSA-69601;Reactome: R-HSA-912631;Reactome: R-HSA-205043;Reactome: R-HSA-68949;Reactome: R-HSA-2979096;Reactome: R-HSA-9645460;Reactome: R-HSA-1236382;Reactome: R-HSA-8939902;Reactome: R-HSA-977225;Reactome: R-HSA-5658442;Reactome: R-HSA-450321;Reactome: R-HSA-174184;Reactome: R-HSA-5689877;Reactome: R-HSA-1169408;Reactome: R-HSA-450408;Reactome: R-HSA-5675221;Reactome: R-HSA-69481;Reactome: R-HSA-975956;Reactome: R-HSA-400253;Reactome: R-HSA-175474;Reactome: R-HSA-3785653;Reactome: R-HSA-72764;Reactome: R-HSA-901032;Reactome: R-HSA-8875360;Reactome: R-HSA-162588;Reactome: R-HSA-4608870;Reactome: R-HSA-8948747;Reactome: R-HSA-5675482;Reactome: R-HSA-450302;Reactome: R-HSA-975163;Reactome: R-HSA-2565942;Reactome: R-HSA-110314;Reactome: R-HSA-9613829;Reactome: R-HSA-8856828;Reactome: R-HSA-174490;Reactome: R-HSA-6804757;Reactome: R-HSA-8854050;Reactome: R-HSA-5656121;Reactome: R-HSA-3134975;Reactome: R-HSA-174084;Reactome: R-HSA-2644606;Reactome: R-HSA-8948751;Reactome: R-HSA-937042;Reactome: R-HSA-174178;Reactome: R-HSA-2672351;Reactome: R-HSA-2173796;Reactome: R-HSA-5696395;Reactome: R-HSA-4641257;Reactome: R-HSA-1253288;Reactome: R-HSA-5678895;Reactome: R-HSA-8863795;Reactome: R-HSA-2122948;Reactome: R-HSA-917937;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-9636383;Reactome: R-HSA-182971;Reactome: R-HSA-2173795;Reactome: R-HSA-6782210;Reactome: R-HSA-5362768;Reactome: R-HSA-5696397;Reactome: R-HSA-1358803;Reactome: R-HSA-9013507;Reactome: R-HSA-5654732;Reactome: R-HSA-5689896;Reactome: R-HSA-5357905;Reactome: R-HSA-8876493;Reactome: R-HSA-5684264;Reactome: R-HSA-5610783;Reactome: R-HSA-5654726;Reactome: R-HSA-975144;Reactome: R-HSA-8939236;Reactome: R-HSA-2173788;Reactome: R-HSA-382556;Reactome: R-HSA-168638;Reactome: R-HSA-9033241;Reactome: R-HSA-202424;Reactome: R-HSA-179409;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-180534;Reactome: R-HSA-8866652;Reactome: R-HSA-174048;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-110312;Reactome: R-HSA-2408557;Reactome: R-HSA-6782135;Reactome: R-HSA-6791226;Reactome: R-HSA-187577;Reactome: R-HSA-9646399;Reactome: R-HSA-156902;Reactome: R-HSA-209543;Reactome: R-HSA-9615710;Reactome: R-HSA-6807004;Reactome: R-HSA-5656169;Reactome: R-HSA-5689901;Reactome: R-HSA-2559580;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-975957;Reactome: R-HSA-1234176;Reactome: R-HSA-209560;Reactome: R-HSA-3769402;Reactome: R-HSA-69541;Reactome: R-HSA-9010553;Reactome: R-HSA-68827;Reactome: R-HSA-69017;Reactome: R-HSA-1799339;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-8856825;Reactome: R-HSA-5654733;Reactome: R-HSA-5696400;Reactome: R-HSA-3322077;Reactome: R-HSA-168927;Reactome: R-HSA-6804760;Reactome: R-HSA-975110;Reactome: R-HSA-6781827;Reactome: R-HSA-936964;Reactome: R-HSA-168928;Reactome: R-HSA-72706;Reactome: R-HSA-174113;Reactome: R-HSA-2691232;Reactome: R-HSA-5693607;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-532668;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-9633012;Reactome: R-HSA-6783310;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-2467813;Reactome: R-HSA-917729;Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-5693565;Reactome: R-HSA-2173791	"Spry regulation of FGF signaling";"IKK complex recruitment mediated by RIP1";"Degradation of DVL";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"TICAM1-dependent activation of IRF3/IRF7";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Oncogene Induced Senescence";"NOTCH1 Intracellular Domain Regulates Transcription";"Pink/Parkin Mediated Mitophagy";"ER-Phagosome pathway";"TNFR1-induced NFkappaB signaling pathway";"CLEC7A (Dectin-1) signaling";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Regulation of FZD by ubiquitination";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Negative regulators of DDX58/IFIH1 signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"E3 ubiquitin ligases ubiquitinate target proteins";"IRAK1 recruits IKK complex";"Negative regulation of FGFR2 signaling";"Viral mRNA Translation";"TCF dependent signaling in response to WNT";"Modulation by Mtb of host immune system";"Cyclin D associated events in G1";"TNFR2 non-canonical NF-kB pathway";"Senescence-Associated Secretory Phenotype (SASP)";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Regulation of TP53 Activity through Phosphorylation";"Degradation of beta-catenin by the destruction complex";"HDR through Homologous Recombination (HRR)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of signaling by CBL";"NRIF signals cell death from the nucleus";"Orc1 removal from chromatin";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Alpha-protein kinase 1 signaling pathway";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Regulation of RUNX2 expression and activity";"Amyloid fiber formation";"Regulation of RAS by GAPs";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Josephin domain DUBs";"ISG15 antiviral mechanism";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Negative regulation of MAPK pathway";"G2/M Checkpoints";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Circadian Clock";"Assembly Of The HIV Virion";"Myoclonic epilepsy of Lafora";"Eukaryotic Translation Termination";"ER Quality Control Compartment (ERQC)";"InlB-mediated entry of Listeria monocytogenes into host cell";"Budding and maturation of HIV virion";"Asymmetric localization of PCP proteins";"Regulation of PTEN localization";"Regulation of necroptotic cell death";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Regulation of PLK1 Activity at G2/M Transition";"Recognition of DNA damage by PCNA-containing replication complex";"Chaperone Mediated Autophagy";"Clathrin-mediated endocytosis";"Membrane binding and targetting of GAG proteins";"Regulation of TP53 Degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Translesion synthesis by POLI";"Regulation of innate immune responses to cytosolic DNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of PTEN stability and activity";"IRAK2 mediated activation of TAK1 complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Stimuli-sensing channels";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of Incision Complex in GG-NER";"Degradation of AXIN";"Downregulation of ERBB4 signaling";"Defective CFTR causes cystic fibrosis";"Downregulation of ERBB2 signaling";"Activated NOTCH1 Transmits Signal to the Nucleus";"Iron uptake and transport";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Prevention of phagosomal-lysosomal fusion";"EGFR downregulation";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Downregulation of ERBB2:ERBB3 signaling";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Negative regulation of FGFR3 signaling";"Ovarian tumor domain proteases";"Regulation of TNFR1 signaling";"InlA-mediated entry of Listeria monocytogenes into host cells";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Degradation of GLI2 by the proteasome";"Negative regulation of FGFR1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downregulation of TGF-beta receptor signaling";"ABC-family proteins mediated transport";"NOD1/2 Signaling Pathway";"Peroxisomal protein import";"Downstream TCR signaling";"APC-Cdc20 mediated degradation of Nek2A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Vpu mediated degradation of CD4";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"Translesion synthesis by REV1";"Selenocysteine synthesis";"Dual incision in TC-NER";"Major pathway of rRNA processing in the nucleolus and cytosol";"SCF(Skp2)-mediated degradation of p27/p21";"Aggrephagy";"Peptide chain elongation";"p75NTR recruits signalling complexes";"Late endosomal microautophagy";"Negative regulation of MET activity";"Termination of translesion DNA synthesis";"Metalloprotease DUBs";"Oxidative Stress Induced Senescence";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NF-kB is activated and signals survival";"Deactivation of the beta-catenin transactivating complex";"Stabilization of p53";"Regulation of expression of SLITs and ROBOs";"CDT1 association with the CDC6:ORC:origin complex";"CDK-mediated phosphorylation and removal of Cdc6";"SRP-dependent cotranslational protein targeting to membrane";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of FGFR4 signaling";"Dual Incision in GG-NER";"Glycogen synthesis";"TICAM1, RIP1-mediated IKK complex recruitment";"Regulation of TP53 Activity through Methylation";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SCF-beta-TrCP mediated degradation of Emi1";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Processing of DNA double-strand break ends";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Fanconi Anemia Pathway";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Separation of Sister Chromatids";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"
Lalb_11580	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
Lalb_13988	5	Reactome: R-HSA-196843;MetaCyc: PWY-5523;MetaCyc: PWY-7863;MetaCyc: PWY-6168;KEGG: 00740+2.7.1.26	"Vitamin B2 (riboflavin) metabolism";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Roseoflavin biosynthesis";"Flavin biosynthesis III (fungi)";"Riboflavin metabolism"
Lalb_00503	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
Lalb_07973	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
Lalb_11572	13	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation"
Lalb_13450	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
Lalb_02420	14	MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7601	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
Lalb_12174	1	Reactome: R-HSA-1632852	"Macroautophagy"
Lalb_10935	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
Lalb_02075	4	Reactome: R-HSA-9615017;Reactome: R-HSA-9614399;Reactome: R-HSA-198693;Reactome: R-HSA-5674400	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of localization of FOXO transcription factors";"AKT phosphorylates targets in the nucleus";"Constitutive Signaling by AKT1 E17K in Cancer"
Lalb_10699	5	Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;Reactome: R-HSA-166208	"HSF1-dependent transactivation";"mTOR signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"mTORC1-mediated signalling"
Lalb_03601	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
Lalb_01448	3	Reactome: R-HSA-8853383;Reactome: R-HSA-6804756;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Regulation of TP53 Activity through Phosphorylation";"Other glycan degradation"
Lalb_04563	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
Lalb_07929	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
Lalb_12239	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
Lalb_05251	1	Reactome: R-HSA-189200	"Cellular hexose transport"
Lalb_02757	6	KEGG: 00785+2.3.1.181;Reactome: R-HSA-196780;MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00780+6.3.4.15;Reactome: R-HSA-3371599	"Lipoic acid metabolism";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin metabolism";"Defective HLCS causes multiple carboxylase deficiency"
Lalb_02708	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
Lalb_12098	17	Reactome: R-HSA-9645460;Reactome: R-HSA-937042;Reactome: R-HSA-937072;Reactome: R-HSA-445989;Reactome: R-HSA-450321;Reactome: R-HSA-168638;Reactome: R-HSA-2871837;Reactome: R-HSA-450302;Reactome: R-HSA-975163;Reactome: R-HSA-4086398;Reactome: R-HSA-202424;Reactome: R-HSA-9020702;Reactome: R-HSA-9014325;Reactome: R-HSA-5689880;Reactome: R-HSA-1169091;Reactome: R-HSA-5357956;Reactome: R-HSA-5607764	"Alpha-protein kinase 1 signaling pathway";"IRAK2 mediated activation of TAK1 complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"NOD1/2 Signaling Pathway";"FCERI mediated NF-kB activation";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Ca2+ pathway";"Downstream TCR signaling";"Interleukin-1 signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Ub-specific processing proteases";"Activation of NF-kappaB in B cells";"TNFR1-induced NFkappaB signaling pathway";"CLEC7A (Dectin-1) signaling"
Lalb_03633	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis"
Lalb_10713	18	Reactome: R-HSA-1482922;MetaCyc: PWY-8051;Reactome: R-HSA-1482839;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-7783;MetaCyc: PWY-6803;Reactome: R-HSA-1482801;Reactome: R-HSA-1482925;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;Reactome: R-HSA-1482788	"Acyl chain remodelling of PI";"Anandamide biosynthesis I";"Acyl chain remodelling of PE";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PS";"Acyl chain remodelling of PG";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Synthesis of PA";"Anandamide biosynthesis II";"Acyl chain remodelling of PC"
Lalb_00547	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus"
Lalb_13182	5	Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-983231;Reactome: R-HSA-2132295	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Factors involved in megakaryocyte development and platelet production";"MHC class II antigen presentation"
Lalb_06029	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
Lalb_02777	6	KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;Reactome: R-HSA-3878781;MetaCyc: PWY-5067;MetaCyc: PWY-622;Reactome: R-HSA-3322077	"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen storage disease type IV (GBE1)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis";"Glycogen synthesis"
Lalb_05097	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
Lalb_11457	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
Lalb_11611	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_04923	3	Reactome: R-HSA-72163;Reactome: R-HSA-430039;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Minor Pathway"
Lalb_01139	16	Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72649	"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Translation initiation complex formation"
Lalb_09651	16	Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72695	"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex"
Lalb_13944	5	Reactome: R-HSA-9609523;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-6807878	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"Cargo concentration in the ER";"COPI-mediated anterograde transport"
Lalb_06101	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
Lalb_10778	56	Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702	"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RAS by GAPs";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Interleukin-1 signaling"
Lalb_00225	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
Lalb_10854	3	Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)"
Lalb_13768	9	Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167161	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation"
Lalb_10879	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
Lalb_04498	1	MetaCyc: PWY-7511	"Protein ubiquitination"
Lalb_13136	3	Reactome: R-HSA-8964058;Reactome: R-HSA-1369062;Reactome: R-HSA-9029569	"HDL remodeling";"ABC transporters in lipid homeostasis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
Lalb_08256	6	Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids"
Lalb_09101	1	Reactome: R-HSA-189200	"Cellular hexose transport"
Lalb_00125	1	Reactome: R-HSA-912446	"Meiotic recombination"
Lalb_06988	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
Lalb_01286	2	Reactome: R-HSA-3359473;Reactome: R-HSA-196741	"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
Lalb_09926	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
Lalb_00087	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_05168	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
Lalb_01668	17	Reactome: R-HSA-5656169;Reactome: R-HSA-174437;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-174417;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-174414;Reactome: R-HSA-110314;Reactome: R-HSA-69166	"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate from the C-strand";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Telomere C-strand (Lagging Strand) Synthesis";"Polymerase switching";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processive synthesis on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate"
Lalb_04274	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300	"SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors"
Lalb_01931	6	MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism"
Lalb_05686	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
Lalb_11550	1	Reactome: R-HSA-156588	"Glucuronidation"
Lalb_13761	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
Lalb_10191	4	KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;MetaCyc: PWY-7382;Reactome: R-HSA-389661	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation"
Lalb_04650	1	Reactome: R-HSA-74217	"Purine salvage"
Lalb_09047	7	Reactome: R-HSA-166208;Reactome: R-HSA-72662;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-429947	"mTORC1-mediated signalling";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Deadenylation of mRNA"
Lalb_13341	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
Lalb_05862	12	Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-450408;Reactome: R-HSA-1169408;Reactome: R-HSA-166208;Reactome: R-HSA-72662;Reactome: R-HSA-429947;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ISG15 antiviral mechanism";"mTORC1-mediated signalling";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Deadenylation of mRNA";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
Lalb_14167	1	Reactome: R-HSA-189200	"Cellular hexose transport"
Lalb_03202	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
Lalb_12053	1	MetaCyc: PWY-7511	"Protein ubiquitination"
Lalb_04994	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
Lalb_01419	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
Lalb_01229	4	KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16	"Cysteine and methionine metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Arginine and proline metabolism"
Lalb_05977	11	Reactome: R-HSA-428890;Reactome: R-HSA-69231;Reactome: R-HSA-2029482;Reactome: R-HSA-5685938;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8939236;Reactome: R-HSA-8940973;Reactome: R-HSA-983231;Reactome: R-HSA-5663213;Reactome: R-HSA-525793;Reactome: R-HSA-5693565	"Role of ABL in ROBO-SLIT signaling";"Cyclin D associated events in G1";"Regulation of actin dynamics for phagocytic cup formation";"HDR through Single Strand Annealing (SSA)";"T cell receptor signaling pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX2 regulates osteoblast differentiation";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases Activate WASPs and WAVEs";"Myogenesis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
Lalb_07940	7	Reactome: R-HSA-2173796;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-2122947	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
Lalb_05449	33	Reactome: R-HSA-73779;Reactome: R-HSA-73863;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-69273;Reactome: R-HSA-167246;Reactome: R-HSA-69231;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-8939236;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-6782210;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-76042;Reactome: R-HSA-73762;Reactome: R-HSA-5696395;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-167152;Reactome: R-HSA-73772;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-6781823	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Termination";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"Cyclin A/B1/B2 associated events during G2/M transition";"Tat-mediated elongation of the HIV-1 transcript";"Cyclin D associated events in G1";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Initiation";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Promoter Escape";"Dual incision in TC-NER";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"Formation of TC-NER Pre-Incision Complex"
Lalb_03711	4	MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49;MetaCyc: PWY-8004	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Pentose phosphate pathway";"Entner-Doudoroff pathway I"
Lalb_08019	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
Lalb_11466	1	Reactome: R-HSA-6798163	"Choline catabolism"
Lalb_12042	8	Reactome: R-HSA-390247;Reactome: R-HSA-6811434;Reactome: R-HSA-5684045;Reactome: R-HSA-9603798;Reactome: R-HSA-2046105;Reactome: R-HSA-983189;Reactome: R-HSA-1369062;Reactome: R-HSA-2046106	"Beta-oxidation of very long chain fatty acids";"COPI-dependent Golgi-to-ER retrograde traffic";"Defective ABCD1 causes adrenoleukodystrophy (ALD)";"Class I peroxisomal membrane protein import";"Linoleic acid (LA) metabolism";"Kinesins";"ABC transporters in lipid homeostasis";"alpha-linolenic acid (ALA) metabolism"
Lalb_01827	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
Lalb_03232	1	Reactome: R-HSA-8949613	"Cristae formation"
Lalb_13474	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
Lalb_09082	10	MetaCyc: PWY-7328;MetaCyc: PWY-3821;MetaCyc: PWY-7344;MetaCyc: PWY-6317;Reactome: R-HSA-5609977;MetaCyc: PWY-6527;KEGG: 00520+5.1.3.2;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6397;Reactome: R-HSA-70370	"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"D-galactose detoxification";"UDP-alpha-D-galactose biosynthesis";"D-galactose degradation I (Leloir pathway)";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose catabolism"
Lalb_07881	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
Lalb_01808	4	Reactome: R-HSA-3000178;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"ECM proteoglycans";"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
Lalb_01761	4	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)"
Lalb_09827	6	Reactome: R-HSA-189085;MetaCyc: PWY-5067;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1;MetaCyc: PWY-622	"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Starch biosynthesis"
Lalb_13414	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
Lalb_00627	3	Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007	"Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy"
Lalb_13075	10	Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167172	"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome"
Lalb_03010	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
Lalb_00250	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
Lalb_05229	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
Lalb_08942	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
Lalb_08537	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
Lalb_02292	6	Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;Reactome: R-HSA-76005;Reactome: R-HSA-114516	"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation"
Lalb_08805	7	MetaCyc: PWY-8026;MetaCyc: PWY-2541;KEGG: 00100+1.3.1.70;Reactome: R-HSA-191273;MetaCyc: PWY-6074;Reactome: R-HSA-9022692;MetaCyc: PWY-7154	"Sterol biosynthesis (methylotrophs)";"Phytosterol biosynthesis (plants)";"Steroid biosynthesis";"Cholesterol biosynthesis";"Zymosterol biosynthesis";"Regulation of MECP2 expression and activity";"Ergosterol biosynthesis II"
Lalb_02614	2	Reactome: R-HSA-983231;Reactome: R-HSA-168138	"Factors involved in megakaryocyte development and platelet production";"Toll Like Receptor 9 (TLR9) Cascade"
Lalb_08740	3	MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689	"Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I"
Lalb_14103	2	Reactome: R-HSA-432722;Reactome: R-HSA-432720	"Golgi Associated Vesicle Biogenesis";"Lysosome Vesicle Biogenesis"
Lalb_02065	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
Lalb_07225	34	KEGG: 00071+1.1.1.1;KEGG: 00010+1.1.1.1;MetaCyc: PWY-6871;MetaCyc: PWY-5076;KEGG: 00980+1.1.1.1;MetaCyc: PWY-5079;MetaCyc: PWY-7118;MetaCyc: PWY-5078;MetaCyc: PWY-3162;MetaCyc: PWY-7396;MetaCyc: PWY-6587;MetaCyc: PWY-5057;MetaCyc: PWY-7013;MetaCyc: PWY-6333;MetaCyc: PWY-5082;KEGG: 00626+1.1.1.1;KEGG: 00592+1.1.1.1;Reactome: R-HSA-162710;MetaCyc: PWY-6802;KEGG: 00350+1.1.1.1;MetaCyc: PWY-6342;KEGG: 00260+1.1.1.1;KEGG: 00982+1.1.1.1;MetaCyc: PWY-5486;KEGG: 00830+1.1.1.1;MetaCyc: PWY-7111;MetaCyc: PWY-5751;KEGG: 00625+1.1.1.1;Reactome: R-HSA-71384;MetaCyc: PWY-7798;MetaCyc: PWY-6313;MetaCyc: PWY-1801;KEGG: 00680+1.1.1.284;MetaCyc: PWY-5480	"Fatty acid degradation";"Glycolysis / Gluconeogenesis";"3-methylbutanol biosynthesis (engineered)";"L-leucine degradation III";"Metabolism of xenobiotics by cytochrome P450";"L-phenylalanine degradation III";"Chitin degradation to ethanol";"L-isoleucine degradation II";"L-tryptophan degradation V (side chain pathway)";"Butanol and isobutanol biosynthesis (engineered)";"Pyruvate fermentation to ethanol III";"L-valine degradation II";"(S)-propane-1,2-diol degradation";"Acetaldehyde biosynthesis I";"L-methionine degradation III";"Naphthalene degradation";"alpha-Linolenic acid metabolism";"Synthesis of glycosylphosphatidylinositol (GPI)";"Salidroside biosynthesis";"Tyrosine metabolism";"Noradrenaline and adrenaline degradation";"Glycine, serine and threonine metabolism";"Drug metabolism - cytochrome P450";"Pyruvate fermentation to ethanol II";"Retinol metabolism";"Pyruvate fermentation to isobutanol (engineered)";"Phenylethanol biosynthesis";"Chloroalkane and chloroalkene degradation";"Ethanol oxidation";"Protein S-nitrosylation and denitrosylation";"Serotonin degradation";"Formaldehyde oxidation II (glutathione-dependent)";"Methane metabolism";"Pyruvate fermentation to ethanol I"
Lalb_12114	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
Lalb_05703	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
Lalb_01465	7	Reactome: R-HSA-1855204;MetaCyc: PWY-7039;MetaCyc: PWY-8052;MetaCyc: PWY-6351;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11	"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism"
Lalb_12759	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_12117	56	Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-174113	"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Degradation of AXIN";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog 'on' state";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"SCF-beta-TrCP mediated degradation of Emi1"
Lalb_07183	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_01431	3	KEGG: 00230+3.6.1.17;Reactome: R-HSA-3299685;KEGG: 00240+3.6.1.17	"Purine metabolism";"Detoxification of Reactive Oxygen Species";"Pyrimidine metabolism"
Lalb_01701	16	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-156827	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression"
Lalb_05403	4	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
Lalb_08479	3	Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154	"Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase"
Lalb_04626	16	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-156827	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression"
Lalb_06387	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
Lalb_04630	1	MetaCyc: PWY-7511	"Protein ubiquitination"
Lalb_04870	3	MetaCyc: PWY-7221;Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions";"Purine metabolism"
Lalb_02066	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
Lalb_08769	16	Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72695	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex"
Lalb_12712	4	Reactome: R-HSA-351202;KEGG: 00270+4.1.1.50;MetaCyc: PWY-6834;KEGG: 00330+4.1.1.50	"Metabolism of polyamines";"Cysteine and methionine metabolism";"Spermidine biosynthesis III";"Arginine and proline metabolism"
Lalb_01487	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
Lalb_01698	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
Lalb_09779	1	Reactome: R-HSA-71064	"Lysine catabolism"
Lalb_13301	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_02068	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
Lalb_10480	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
Lalb_05149	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
Lalb_08057	13	Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72689	"Selenocysteine synthesis";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits"
Lalb_05422	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
Lalb_02860	7	KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;KEGG: 00471+3.5.1.2;Reactome: R-HSA-210500;Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2	"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"D-Glutamine and D-glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"Arginine biosynthesis"
Lalb_03680	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
Lalb_07349	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
Lalb_06231	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
Lalb_08151	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
Lalb_13763	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
Lalb_13658	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
Lalb_08764	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
Lalb_11791	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
Lalb_05729	1	Reactome: R-HSA-189200	"Cellular hexose transport"
Lalb_06173	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
Lalb_02533	1	Reactome: R-HSA-446203	"Asparagine N-linked glycosylation"
Lalb_13449	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
Lalb_05244	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
Lalb_09865	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
Lalb_01391	4	Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-381771;Reactome: R-HSA-422085	"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin"
Lalb_00605	27	Reactome: R-HSA-5619107;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-159230	"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"snRNP Assembly";"ISG15 antiviral mechanism";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA"
Lalb_12857	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
Lalb_03318	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
Lalb_08655	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
Lalb_00135	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
Lalb_00161	57	Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-211733;Reactome: R-HSA-6798695;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-180585	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neutrophil degranulation";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Interleukin-1 signaling";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"Degradation of AXIN";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G"
Lalb_13120	5	Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-389960	"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC"
Lalb_04208	7	Reactome: R-HSA-1362277;Reactome: R-HSA-69231;Reactome: R-HSA-69205;Reactome: R-HSA-2173796;Reactome: R-HSA-6804114;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300	"Transcription of E2F targets under negative control by DREAM complex";"Cyclin D associated events in G1";"G1/S-Specific Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
Lalb_02595	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
Lalb_00938	3	Reactome: R-HSA-72163;Reactome: R-HSA-5250924;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway"
Lalb_06513	6	Reactome: R-HSA-913709;MetaCyc: PWY-7433;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122	"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis"
Lalb_12180	1	Reactome: R-HSA-8951664	"Neddylation"
Lalb_04182	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
Lalb_13108	7	Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
Lalb_09911	7	KEGG: 00230+2.4.2.14;KEGG: 00250+2.4.2.14;Reactome: R-HSA-73817;MetaCyc: PWY-7282;MetaCyc: PWY-6121;MetaCyc: PWY-6277;MetaCyc: PWY-6122	"Purine metabolism";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II"
Lalb_07931	20	Reactome: R-HSA-446343;Reactome: R-HSA-9609690;Reactome: R-HSA-75892;Reactome: R-HSA-202733;Reactome: R-HSA-3000178;Reactome: R-HSA-210991;Reactome: R-HSA-216083;Reactome: R-HSA-1566977;Reactome: R-HSA-6785807;Reactome: R-HSA-8875513;Reactome: R-HSA-3000170;Reactome: R-HSA-447041;Reactome: R-HSA-1566948;Reactome: R-HSA-8874081;Reactome: R-HSA-5663220;Reactome: R-HSA-198933;Reactome: R-HSA-445144;Reactome: R-HSA-416700;Reactome: R-HSA-2129379;Reactome: R-HSA-3000157	"Localization of the PINCH-ILK-PARVIN complex to focal adhesions";"HCMV Early Events";"Platelet Adhesion to exposed collagen";"Cell surface interactions at the vascular wall";"ECM proteoglycans";"Basigin interactions";"Integrin cell surface interactions";"Fibronectin matrix formation";"Interleukin-4 and Interleukin-13 signaling";"MET interacts with TNS proteins";"Syndecan interactions";"CHL1 interactions";"Elastic fibre formation";"MET activates PTK2 signaling";"RHO GTPases Activate Formins";"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell";"Signal transduction by L1";"Other semaphorin interactions";"Molecules associated with elastic fibres";"Laminin interactions"
Lalb_12579	1	Reactome: R-HSA-156588	"Glucuronidation"
Lalb_08286	2	Reactome: R-HSA-163841;KEGG: 00900+2.1.1.100	"Gamma carboxylation, hypusine formation and arylsulfatase activation";"Terpenoid backbone biosynthesis"
Lalb_04069	3	Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation"
Lalb_01648	1	MetaCyc: PWY-7511	"Protein ubiquitination"
Lalb_05789	2	Reactome: R-HSA-69231;Reactome: R-HSA-8934593	"Cyclin D associated events in G1";"Regulation of RUNX1 Expression and Activity"
Lalb_08872	4	MetaCyc: PWY-5686;MetaCyc: PWY-7790;KEGG: 00240+3.5.2.3;MetaCyc: PWY-7791	"UMP biosynthesis I";"UMP biosynthesis II";"Pyrimidine metabolism";"UMP biosynthesis III"
Lalb_08190	1	Reactome: R-HSA-8964572	"Lipid particle organization"
Lalb_08382	1	Reactome: R-HSA-912446	"Meiotic recombination"
Lalb_03205	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
Lalb_13083	20	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;KEGG: 04926+2.7.11.1;Reactome: R-HSA-8943724;KEGG: 05170+2.7.11.1;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-3371571;Reactome: R-HSA-6804757;Reactome: R-HSA-5628897;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-389357;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Amino acids regulate mTORC1";"mTOR signalling";"Relaxin signaling pathway";"Regulation of PTEN gene transcription";"Human immunodeficiency virus 1 infection";"mTORC1-mediated signalling";"Macroautophagy";"HSF1-dependent transactivation";"Regulation of TP53 Degradation";"TP53 Regulates Metabolic Genes";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"Thermogenesis";"PI3K-Akt signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"CD28 dependent PI3K/Akt signaling";"Human papillomavirus infection"
Lalb_01140	5	Reactome: R-HSA-71336;Reactome: R-HSA-6798695;KEGG: 00030+4.1.2.4;MetaCyc: PWY-8060;MetaCyc: PWY-7180	"Pentose phosphate pathway";"Neutrophil degranulation";"Pentose phosphate pathway";"2-deoxy-D-ribose degradation I";"2-deoxy-alpha-D-ribose 1-phosphate degradation"
Lalb_01678	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling"
Lalb_04711	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
Lalb_10320	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
Lalb_10642	4	Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5358346	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis"
Lalb_02571	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
Lalb_12572	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
Lalb_09808	5	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-159231	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript"
Lalb_10335	4	KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism"
Lalb_13639	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
Lalb_10603	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
Lalb_02341	10	Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-2197563;Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-9013695	"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH2 intracellular domain regulates transcription";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"NOTCH4 Intracellular Domain Regulates Transcription"
Lalb_13302	7	Reactome: R-HSA-1855183;Reactome: R-HSA-8856828;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.36;MetaCyc: PWY-6368;Reactome: R-HSA-1855204	"Synthesis of IP2, IP, and Ins in the cytosol";"Clathrin-mediated endocytosis";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Synthesis of IP3 and IP4 in the cytosol"
Lalb_08348	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_12126	34	Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-9639288;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-2467813;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-168276	"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Amino acids regulate mTORC1";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"snRNP Assembly";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Separation of Sister Chromatids";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways"
Lalb_10147	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
Lalb_09336	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
Lalb_09281	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
Lalb_04569	6	KEGG: 00195+7.1.2.2;Reactome: R-HSA-8949613;Reactome: R-HSA-1268020;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;Reactome: R-HSA-163210	"Photosynthesis";"Cristae formation";"Mitochondrial protein import";"ATP biosynthesis";"Oxidative phosphorylation";"Formation of ATP by chemiosmotic coupling"
Lalb_10205	13	Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72689	"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits"
Lalb_11449	8	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9633012	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
Lalb_11653	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
Lalb_10731	3	KEGG: 00480+4.3.2.9;Reactome: R-HSA-174403;MetaCyc: PWY-4041	"Glutathione metabolism";"Glutathione synthesis and recycling";"Gamma-glutamyl cycle"
Lalb_06846	13	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation"
Lalb_01887	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
Lalb_01277	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
Lalb_09987	4	KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;Reactome: R-HSA-1660662;MetaCyc: PWY-7119	"Sphingolipid metabolism";"Ceramide degradation (generic)";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)"
Lalb_00223	6	Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72649	"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation"
Lalb_08594	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
Lalb_04735	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
Lalb_13962	3	Reactome: R-HSA-1236974;Reactome: R-HSA-9609523;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane"
Lalb_12184	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
Lalb_01934	10	KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2160916;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00511+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00052+3.2.1.23	"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation";"Sphingolipid metabolism";"MPS VII - Sly syndrome";"Glycosaminoglycan degradation";"HS-GAG degradation";"Other glycan degradation";"Neutrophil degranulation";"Galactose metabolism"
Lalb_11373	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
Lalb_06515	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
Lalb_13273	3	Reactome: R-HSA-4419969;Reactome: R-HSA-2980766;Reactome: R-HSA-2995383	"Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown";"Initiation of Nuclear Envelope Reformation"
Lalb_11578	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
Lalb_07487	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
Lalb_09971	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
Lalb_00399	6	Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-69052	"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state"
Lalb_11425	2	Reactome: R-HSA-5689880;Reactome: R-HSA-3214847	"Ub-specific processing proteases";"HATs acetylate histones"
Lalb_05078	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
Lalb_04992	2	MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Protein ubiquitination";"Neutrophil degranulation"
Lalb_04810	9	Reactome: R-HSA-4420097;Reactome: R-HSA-416482;Reactome: R-HSA-2871809;Reactome: R-HSA-114604;Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-2029482;Reactome: R-HSA-2871796;Reactome: R-HSA-5218920	"VEGFA-VEGFR2 Pathway";"G alpha (12/13) signalling events";"FCERI mediated Ca+2 mobilization";"GPVI-mediated activation cascade";"NRAGE signals death through JNK";"Rho GTPase cycle";"Regulation of actin dynamics for phagocytic cup formation";"FCERI mediated MAPK activation";"VEGFR2 mediated vascular permeability"
Lalb_04959	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
Lalb_04933	2	Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15	"Pentose phosphate pathway";"Pentose phosphate pathway"
Lalb_05553	3	MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646	"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification"
Lalb_07502	7	MetaCyc: PWY-6614;KEGG: 00670+1.5.1.3;Reactome: R-HSA-196757;KEGG: 00790+1.5.1.3;MetaCyc: PWY-3841;Reactome: R-HSA-69205;Reactome: R-HSA-1474151	"Tetrahydrofolate biosynthesis";"One carbon pool by folate";"Metabolism of folate and pterines";"Folate biosynthesis";"Folate transformations II (plants)";"G1/S-Specific Transcription";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
Lalb_09087	5	Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-5693607;Reactome: R-HSA-69473	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint"
Lalb_07985	9	Reactome: R-HSA-1855204;MetaCyc: PWY-6367;Reactome: R-HSA-416476;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-112043;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11	"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system"
Lalb_03252	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
Lalb_06474	9	KEGG: 00710+1.2.1.12;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-5484;Reactome: R-HSA-70263;KEGG: 00010+1.2.1.12;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-6901	"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation"
Lalb_10868	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_09984	3	Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476	"G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events"
Lalb_05245	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
Lalb_06578	31	MetaCyc: PWY-5966-1;Reactome: R-HSA-199220;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5989;MetaCyc: PWY-8047;MetaCyc: PWY-4381;MetaCyc: PWY-5147;MetaCyc: PWY-7663;Reactome: R-HSA-2426168;MetaCyc: PWY-5973;MetaCyc: PWY-6113;MetaCyc: PWY-7723;MetaCyc: PWY-7664;MetaCyc: PWY-5971;MetaCyc: PWY-6282;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7858;MetaCyc: PWY-5142;MetaCyc: PWY-6519;MetaCyc: PWY-5994;Reactome: R-HSA-9029558;MetaCyc: PWY-8049;MetaCyc: PWY-5366;MetaCyc: PWY-5367;MetaCyc: PWY-7746;Reactome: R-HSA-163765;MetaCyc: PWY-6799;MetaCyc: PWYG-321;MetaCyc: PWY-7388;MetaCyc: PWY-8012;Reactome: R-HSA-75105	"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"Fatty acid biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Bryostatin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Oleate biosynthesis I (plants)";"Gondoate biosynthesis (anaerobic)";"Activation of gene expression by SREBF (SREBP)";"Cis-vaccenate biosynthesis";"Superpathway of mycolate biosynthesis";"Bacterial bioluminescence";"Oleate biosynthesis IV (anaerobic)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Biotin metabolism";"(5Z)-dodecenoate biosynthesis II";"Acyl-[acyl-carrier protein] thioesterase pathway";"8-amino-7-oxononanoate biosynthesis I";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Pederin biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Petroselinate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (plant mitochondria)";"";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Mupirocin biosynthesis";"Fatty acyl-CoA biosynthesis"
Lalb_04502	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
Lalb_11474	1	Reactome: R-HSA-6798163	"Choline catabolism"
Lalb_04848	7	Reactome: R-HSA-1483166;KEGG: 00565+3.1.4.4;KEGG: 00564+3.1.4.4;MetaCyc: PWY-3561;MetaCyc: PWY-7039;Reactome: R-HSA-1483148;Reactome: R-HSA-2029485	"Synthesis of PA";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Choline biosynthesis III";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of PG";"Role of phospholipids in phagocytosis"
Lalb_11455	4	MetaCyc: PWY-7219;KEGG: 00230+6.3.4.4;KEGG: 00250+6.3.4.4;Reactome: R-HSA-73817	"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis"
Lalb_04991	8	MetaCyc: PWY-1861;KEGG: 00051+5.3.1.6;Reactome: R-HSA-6791461;KEGG: 00030+5.3.1.6;KEGG: 00710+5.3.1.6;MetaCyc: PWY-5723;Reactome: R-HSA-5659996;Reactome: R-HSA-71336	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"RPIA deficiency: failed conversion of RU5P to R5P";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Rubisco shunt";"RPIA deficiency: failed conversion of R5P to RU5P";"Pentose phosphate pathway"
Lalb_00196	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
Lalb_06033	1	MetaCyc: PWY-7511	"Protein ubiquitination"
Lalb_04312	11	Reactome: R-HSA-5223345;MetaCyc: PWY-8001;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-7559;MetaCyc: PWY-7112;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00430+2.3.2.2	"Miscellaneous transport and binding events";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Taurine and hypotaurine metabolism"
Lalb_02510	3	Reactome: R-HSA-189451;KEGG: 00860+1.3.3.3;MetaCyc: PWY-7159	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
Lalb_06248	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
Lalb_06631	1	MetaCyc: PWY-7511	"Protein ubiquitination"
Lalb_10855	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
Lalb_11024	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
Lalb_09562	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
Lalb_03766	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7269;MetaCyc: PWY-7268;Reactome: R-HSA-196807	"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism"
Lalb_09450	17	Reactome: R-HSA-912446;Reactome: R-HSA-1834949;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5685939;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-6804756;Reactome: R-HSA-5693548;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693565;Reactome: R-HSA-5693616	"Meiotic recombination";"Cytosolic sensors of pathogen-associated DNA";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through MMEJ (alt-NHEJ)";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Regulation of TP53 Activity through Phosphorylation";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange"
Lalb_06636	3	Reactome: R-HSA-2408508;Reactome: R-HSA-1614603;Reactome: R-HSA-1614558	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine"
Lalb_12212	16	Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72649	"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation"
Lalb_02117	24	Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-437239;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6811434	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Recycling pathway of L1";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Aggrephagy";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-dependent Golgi-to-ER retrograde traffic"
Lalb_05595	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
Lalb_01354	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
Lalb_12989	2	Reactome: R-HSA-1660499;Reactome: R-HSA-211981	"Synthesis of PIPs at the plasma membrane";"Xenobiotics"
Lalb_04939	5	MetaCyc: PWY-7282;Reactome: R-HSA-6798695;MetaCyc: PWY-7204;KEGG: 00750+2.7.1.35;Reactome: R-HSA-964975	"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Neutrophil degranulation";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate"
Lalb_08486	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
Lalb_03409	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
Lalb_01272	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
Lalb_09127	15	Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-2173796;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-176034;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-6807505	"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Interactions of Tat with host cellular proteins";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes"
Lalb_09138	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
Lalb_13205	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
Lalb_03105	1	Reactome: R-HSA-8951664	"Neddylation"
Lalb_12108	5	Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6781823	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex"
Lalb_06614	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
Lalb_07085	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
Lalb_12521	4	Reactome: R-HSA-69202;Reactome: R-HSA-8953750;Reactome: R-HSA-1362277;Reactome: R-HSA-69656	"Cyclin E associated events during G1/S transition";"Transcriptional Regulation by E2F6";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry"
Lalb_03152	6	Reactome: R-HSA-6804759;Reactome: R-HSA-139915;Reactome: R-HSA-6803204;Reactome: R-HSA-6803205;Reactome: R-HSA-6803211;Reactome: R-HSA-6803207	"Regulation of TP53 Activity through Association with Co-factors";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Caspase Activators and Caspases"
Lalb_08179	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
Lalb_12462	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
Lalb_06454	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
Lalb_05098	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
Lalb_09390	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
Lalb_00542	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
Lalb_08134	3	Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"snRNP Assembly";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
Lalb_06511	20	MetaCyc: PWY-7340;MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-5136;MetaCyc: PWY-7007;MetaCyc: PWY-6837;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-6920;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7574;MetaCyc: PWY-7606;MetaCyc: PWY-7858;MetaCyc: PWY-7291	"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid degradation";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"Peroxisomal protein import";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoyl-coa degradation II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(5Z)-dodecenoate biosynthesis II";"Oleate beta-oxidation (isomerase-dependent, yeast)"
Lalb_09978	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
Lalb_10008	2	Reactome: R-HSA-6798695;Reactome: R-HSA-532668	"Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
Lalb_14161	13	Reactome: R-HSA-182218;Reactome: R-HSA-416993;Reactome: R-HSA-5140745;Reactome: R-HSA-8866427;Reactome: R-HSA-3928665;Reactome: R-HSA-437239;Reactome: R-HSA-8964038;Reactome: R-HSA-5099900;Reactome: R-HSA-2132295;Reactome: R-HSA-8856825;Reactome: R-HSA-167590;Reactome: R-HSA-8856828;Reactome: R-HSA-177504	"Nef Mediated CD8 Down-regulation";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"VLDLR internalisation and degradation";"EPH-ephrin mediated repulsion of cells";"Recycling pathway of L1";"LDL clearance";"WNT5A-dependent internalization of FZD4";"MHC class II antigen presentation";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"Clathrin-mediated endocytosis";"Retrograde neurotrophin signalling"
Lalb_00673	27	Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-170822	"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"snRNP Assembly";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein"
Lalb_04414	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
Lalb_09591	11	Reactome: R-HSA-9018519;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082;Reactome: R-HSA-3214858;Reactome: R-HSA-400253;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-6804114;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781	"Estrogen-dependent gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression";"RMTs methylate histone arginines";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression"
Lalb_14012	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
Lalb_08786	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
Lalb_11911	5	Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-6798695;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"Neutrophil degranulation";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
Lalb_05363	6	Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;MetaCyc: PWY-7426	"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)"
Lalb_02910	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
Lalb_01669	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
Lalb_00631	2	Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
Lalb_14727	3	Reactome: R-HSA-110357;Reactome: R-HSA-110330;Reactome: R-HSA-110331	"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine"
Lalb_10976	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
Lalb_04685	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
Lalb_02608	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
Lalb_09905	3	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109	"Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis"
Lalb_10384	14	KEGG: 00650+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-6728;KEGG: 00720+1.3.5.1;KEGG: 00020+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-7254;MetaCyc: PWY-7279;MetaCyc: PWY-3781;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-561;MetaCyc: PWY-4302;KEGG: 00190+1.3.5.1	"Butanoate metabolism";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Respiratory electron transport";"TCA cycle VII (acetate-producers)";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration III (alternative oxidase pathway)";"Oxidative phosphorylation"
Lalb_10400	5	KEGG: 00785+6.3.1.20;Reactome: R-HSA-389661;MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181	"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism"
Lalb_14454	1	Reactome: R-HSA-156588	"Glucuronidation"
Lalb_09881	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
Lalb_04186	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
Lalb_06981	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
Lalb_10703	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
Lalb_01926	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
Lalb_04003	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
Lalb_14013	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
Lalb_09797	29	Reactome: R-HSA-73762;Reactome: R-HSA-76042;Reactome: R-HSA-167160;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-167161;Reactome: R-HSA-73863;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-6782135;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-167162;Reactome: R-HSA-427413;Reactome: R-HSA-72086;Reactome: R-HSA-75955;Reactome: R-HSA-6781827;Reactome: R-HSA-75953;Reactome: R-HSA-5696395;Reactome: R-HSA-674695	"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"HIV Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"Dual incision in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape";"NoRC negatively regulates rRNA expression";"mRNA Capping";"RNA Polymerase II Transcription Elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Pre-transcription Events"
Lalb_02511	2	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
Lalb_10596	26	Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-389960;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-983189;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-6807878	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"Cilium Assembly";"Formation of tubulin folding intermediates by CCT/TriC";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"Kinesins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"COPI-mediated anterograde transport"
Lalb_00287	31	MetaCyc: PWY-7388;MetaCyc: PWY-8012;MetaCyc: PWYG-321;Reactome: R-HSA-75105;MetaCyc: PWY-7746;Reactome: R-HSA-163765;MetaCyc: PWY-6799;MetaCyc: PWY-5366;MetaCyc: PWY-8049;MetaCyc: PWY-5367;MetaCyc: PWY-7858;MetaCyc: PWY-5142;MetaCyc: PWY-6519;Reactome: R-HSA-9029558;MetaCyc: PWY-5994;MetaCyc: PWY-7664;MetaCyc: PWY-5971;MetaCyc: PWY-6282;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6113;MetaCyc: PWY-5973;MetaCyc: PWY-7723;MetaCyc: PWY-5989;MetaCyc: PWY-8047;MetaCyc: PWY-4381;MetaCyc: PWY-7663;MetaCyc: PWY-5147;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;MetaCyc: PWY-5966-1;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14	"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Mupirocin biosynthesis";"";"Fatty acyl-CoA biosynthesis";"Mycobacterial sulfolipid biosynthesis";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (plant mitochondria)";"Palmitoleate biosynthesis II (plants and bacteria)";"Pederin biosynthesis";"Petroselinate biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Acyl-[acyl-carrier protein] thioesterase pathway";"8-amino-7-oxononanoate biosynthesis I";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Oleate biosynthesis IV (anaerobic)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Biotin metabolism";"Superpathway of mycolate biosynthesis";"Cis-vaccenate biosynthesis";"Bacterial bioluminescence";"Stearate biosynthesis II (bacteria and plants)";"Bryostatin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Gondoate biosynthesis (anaerobic)";"Oleate biosynthesis I (plants)";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis"
Lalb_08562	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_13070	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
Lalb_09932	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_10820	4	KEGG: 00970+2.9.1.2;KEGG: 00450+2.9.1.2;MetaCyc: PWY-6281;Reactome: R-HSA-2408557	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis"
Lalb_01700	5	Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724	"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription"
Lalb_00541	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
Lalb_02965	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
Lalb_05102	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
Lalb_06308	12	MetaCyc: PWY-6527;MetaCyc: PWY-3801;MetaCyc: PWY-7343;MetaCyc: PWY-7238;KEGG: 00500+2.7.7.9;Reactome: R-HSA-3322077;KEGG: 00052+2.7.7.9;KEGG: 00040+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-7817;KEGG: 00561+2.7.7.9;KEGG: 00520+2.7.7.9	"Stachyose degradation";"Sucrose degradation II (sucrose synthase)";"UDP-alpha-D-glucose biosynthesis I";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Glycogen synthesis";"Galactose metabolism";"Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Amino sugar and nucleotide sugar metabolism"
Lalb_05357	13	Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
Lalb_12523	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
Lalb_10119	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
Lalb_09914	7	MetaCyc: PWY-7511;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-983168;Reactome: R-HSA-3108214	"Protein ubiquitination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Antigen processing: Ubiquitination & Proteasome degradation";"SUMOylation of DNA damage response and repair proteins"
Lalb_06019	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1799339	"Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane"
Lalb_05506	9	Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-75953	"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation"
Lalb_00945	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
Lalb_07415	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
Lalb_05140	2	Reactome: R-HSA-977225;Reactome: R-HSA-8854214	"Amyloid fiber formation";"TBC/RABGAPs"
Lalb_08593	6	Reactome: R-HSA-1268020;KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;Reactome: R-HSA-71403	"Mitochondrial protein import";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Citric acid cycle (TCA cycle)"
Lalb_06046	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
Lalb_08907	2	Reactome: R-HSA-422356;Reactome: R-HSA-112308	"Regulation of insulin secretion";"Presynaptic depolarization and calcium channel opening"
Lalb_04568	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
Lalb_02476	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
Lalb_02177	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
Lalb_05143	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
Lalb_08691	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
Lalb_07293	29	Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-73863;Reactome: R-HSA-6782210;Reactome: R-HSA-73762;Reactome: R-HSA-76042;Reactome: R-HSA-167160;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-6781827;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-73772;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135	"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Termination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase I Promoter Escape";"Dual Incision in GG-NER";"Dual incision in TC-NER"
Lalb_03817	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
Lalb_00834	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
Lalb_13935	4	Reactome: R-HSA-9615710;Reactome: R-HSA-9646399;Reactome: R-HSA-3899300;Reactome: R-HSA-9613829	"Late endosomal microautophagy";"Aggrephagy";"SUMOylation of transcription cofactors";"Chaperone Mediated Autophagy"
Lalb_02935	16	Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975957	"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
Lalb_04299	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
Lalb_11608	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_01327	4	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
Lalb_07959	1	Reactome: R-HSA-191859	"snRNP Assembly"
Lalb_00262	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
Lalb_05300	27	Reactome: R-HSA-170822;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-4085377	"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"snRNP Assembly";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins"
Lalb_01812	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
Lalb_07579	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
Lalb_07212	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_00585	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
Lalb_11252	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
Lalb_10221	4	Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
Lalb_04292	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
Lalb_10201	22	KEGG: 00500+5.3.1.9;Reactome: R-HSA-5628897;Reactome: R-HSA-6798695;KEGG: 00010+5.3.1.9;MetaCyc: PWY-5054;MetaCyc: PWY-621;MetaCyc: PWY-5384;MetaCyc: PWY-6981;MetaCyc: PWY-6142;MetaCyc: PWY-5659;KEGG: 00030+5.3.1.9;MetaCyc: PWY-8013;MetaCyc: PWY-622;MetaCyc: PWY-7385;Reactome: R-HSA-70171;MetaCyc: PWY-6992;MetaCyc: PWY-3801;MetaCyc: PWY-7347;MetaCyc: PWY-5514;MetaCyc: PWY-7238;Reactome: R-HSA-70263;KEGG: 00520+5.3.1.9	"Starch and sucrose metabolism";"TP53 Regulates Metabolic Genes";"Neutrophil degranulation";"Glycolysis / Gluconeogenesis";"D-sorbitol biosynthesis I";"Sucrose degradation III (sucrose invertase)";"Sucrose degradation IV (sucrose phosphorylase)";"Chitin biosynthesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"GDP-mannose biosynthesis";"Pentose phosphate pathway";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Starch biosynthesis";"1,3-propanediol biosynthesis (engineered)";"Glycolysis";"1,5-anhydrofructose degradation";"Sucrose degradation II (sucrose synthase)";"Sucrose biosynthesis III";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Sucrose biosynthesis II";"Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism"
Lalb_03302	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
Lalb_06816	4	KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
Lalb_09628	18	Reactome: R-HSA-1566948;Reactome: R-HSA-6802955;Reactome: R-HSA-3000170;Reactome: R-HSA-9649948;Reactome: R-HSA-4420097;Reactome: R-HSA-6802948;Reactome: R-HSA-114608;Reactome: R-HSA-445144;Reactome: R-HSA-354192;Reactome: R-HSA-2129379;Reactome: R-HSA-6802952;Reactome: R-HSA-5674135;Reactome: R-HSA-3000178;Reactome: R-HSA-216083;Reactome: R-HSA-354194;Reactome: R-HSA-6802946;Reactome: R-HSA-210990;Reactome: R-HSA-372708	"Elastic fibre formation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Syndecan interactions";"Signaling downstream of RAS mutants";"VEGFA-VEGFR2 Pathway";"Signaling by high-kinase activity BRAF mutants";"Platelet degranulation";"Signal transduction by L1";"Integrin signaling";"Molecules associated with elastic fibres";"Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation";"ECM proteoglycans";"Integrin cell surface interactions";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"Signaling by moderate kinase activity BRAF mutants";"PECAM1 interactions";"p130Cas linkage to MAPK signaling for integrins"
Lalb_06298	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
Lalb_08899	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
Lalb_00304	6	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters"
Lalb_05021	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
Lalb_13953	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
Lalb_12153	1	MetaCyc: PWY-7511	"Protein ubiquitination"
Lalb_12211	10	Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-381042;Reactome: R-HSA-9648895;Reactome: R-HSA-72731;Reactome: R-HSA-72695;Reactome: R-HSA-382556	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"PERK regulates gene expression";"Response of EIF2AK1 (HRI) to heme deficiency";"Recycling of eIF2:GDP";"Formation of the ternary complex, and subsequently, the 43S complex";"ABC-family proteins mediated transport"
Lalb_03587	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_02625	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
Lalb_10326	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
Lalb_10377	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
Lalb_04868	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
Lalb_05761	4	Reactome: R-HSA-210991;Reactome: R-HSA-71240;Reactome: R-HSA-352230;Reactome: R-HSA-5660862	"Basigin interactions";"Tryptophan catabolism";"Amino acid transport across the plasma membrane";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)"
Lalb_11225	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
Lalb_04298	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
Lalb_14051	11	Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-68952;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-68962;Reactome: R-HSA-174430	"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"DNA replication initiation";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation"
Lalb_09806	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
Lalb_00752	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
Lalb_11105	14	Reactome: R-HSA-196757;KEGG: 00630+2.1.2.1;KEGG: 00670+2.1.2.1;KEGG: 00260+2.1.2.1;MetaCyc: PWY-181;MetaCyc: PWY-3661;KEGG: 00680+2.1.2.1;MetaCyc: PWY-1622;MetaCyc: PWY-3841;MetaCyc: PWY-3661-1;KEGG: 00460+2.1.2.1;MetaCyc: PWY-5497;MetaCyc: PWY-2161;MetaCyc: PWY-2201	"Metabolism of folate and pterines";"Glyoxylate and dicarboxylate metabolism";"One carbon pool by folate";"Glycine, serine and threonine metabolism";"Photorespiration ";"Glycine betaine degradation I";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Folate transformations II (plants)";"Glycine betaine degradation II (mammalian)";"Cyanoamino acid metabolism";"Purine nucleobases degradation II (anaerobic)";"Folate polyglutamylation";"Folate transformations I"
Lalb_06450	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_12661	5	Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-389357	"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling"
Lalb_01106	11	MetaCyc: PWY-7782;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8051;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8052;Reactome: R-HSA-2029485;MetaCyc: PWY-6453;MetaCyc: PWY-8055;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8053;KEGG: 00565+3.1.3.4	"Plasmalogen biosynthesis";"Sphingolipid metabolism";"Anandamide biosynthesis I";"Glycerolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Role of phospholipids in phagocytosis";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Ether lipid metabolism"
Lalb_08161	4	Reactome: R-HSA-73817;KEGG: 00250+6.3.4.4;KEGG: 00230+6.3.4.4;MetaCyc: PWY-7219	"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
Lalb_13167	15	Reactome: R-HSA-5689896;Reactome: R-HSA-111465;Reactome: R-HSA-5358749;Reactome: R-HSA-195253;Reactome: R-HSA-5467348;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-5339716;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-5467333;Reactome: R-HSA-5358747;Reactome: R-HSA-3769402;Reactome: R-HSA-5358751	"Ovarian tumor domain proteases";"Apoptotic cleavage of cellular proteins";"S37 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Misspliced GSK3beta mutants stabilize beta-catenin";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants are not K63 polyubiquitinated";"S33 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"S45 mutants of beta-catenin aren't phosphorylated"
Lalb_09759	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
Lalb_06885	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
Lalb_10635	14	MetaCyc: PWY-6351;MetaCyc: PWY-8052;MetaCyc: PWY-7039;Reactome: R-HSA-112043;Reactome: R-HSA-434316;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;Reactome: R-HSA-4086398;Reactome: R-HSA-418217;Reactome: R-HSA-500657;Reactome: R-HSA-1855204;Reactome: R-HSA-399997;MetaCyc: PWY-6367;Reactome: R-HSA-416476	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Ca2+ pathway";"G beta:gamma signalling through PLC beta";"Presynaptic function of Kainate receptors";"Synthesis of IP3 and IP4 in the cytosol";"Acetylcholine regulates insulin secretion";"D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events"
Lalb_02291	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_07806	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
Lalb_09962	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
Lalb_13971	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
Lalb_09680	6	Reactome: R-HSA-380994;Reactome: R-HSA-9633012;Reactome: R-HSA-8963693;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895;Reactome: R-HSA-913709	"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"O-linked glycosylation of mucins"
Lalb_09875	1	Reactome: R-HSA-156588	"Glucuronidation"
Lalb_09191	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
Lalb_14135	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
Lalb_11510	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
Lalb_01070	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
Lalb_11114	3	Reactome: R-HSA-1236974;Reactome: R-HSA-9609523;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane"
Lalb_03581	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_09655	16	Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72764	"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination"
Lalb_12982	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
Lalb_10958	5	Reactome: R-HSA-2894862;Reactome: R-HSA-3214815;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
Lalb_14001	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
Lalb_03929	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
Lalb_07383	4	Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-400511	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
Lalb_08869	4	MetaCyc: PWY-7204;Reactome: R-HSA-964975;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7282	"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
Lalb_13401	3	Reactome: R-HSA-8876198;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
Lalb_08093	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_13349	1	Reactome: R-HSA-189200	"Cellular hexose transport"
Lalb_10299	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
Lalb_12781	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
Lalb_07218	9	Reactome: R-HSA-2173788;Reactome: R-HSA-3645790;Reactome: R-HSA-3642279;Reactome: R-HSA-5689603;Reactome: R-HSA-3304356;Reactome: R-HSA-2173791;Reactome: R-HSA-2173789;Reactome: R-HSA-3656535;Reactome: R-HSA-3656532	"Downregulation of TGF-beta receptor signaling";"TGFBR2 Kinase Domain Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer";"UCH proteinases";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGF-beta receptor signaling activates SMADs";"TGFBR1 LBD Mutants in Cancer";"TGFBR1 KD Mutants in Cancer"
Lalb_11940	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_09252	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
Lalb_06837	4	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex"
Lalb_05146	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
Lalb_07471	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
Lalb_01570	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
Lalb_12648	8	Reactome: R-HSA-499943;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7197;MetaCyc: PWY-7187;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-6545	"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
Lalb_07408	2	Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58	"Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis"
Lalb_02980	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
Lalb_01985	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_00268	3	KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508;Reactome: R-HSA-418597	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"G alpha (z) signalling events"
Lalb_01763	10	MetaCyc: PWY-5839;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5892;MetaCyc: PWY-5844;MetaCyc: PWY-5849;MetaCyc: PWY-5895;MetaCyc: PWY-7996;Reactome: R-HSA-2142789;MetaCyc: PWY-5891;MetaCyc: PWY-5890	"Menaquinol-7 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-4 biosynthesis I";"Ubiquinol biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-10 biosynthesis"
Lalb_13453	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
Lalb_00602	5	KEGG: 00270+1.1.1.95;KEGG: 00680+1.1.1.95;Reactome: R-HSA-977347;KEGG: 00260+1.1.1.95;MetaCyc: PWY-8010	"Cysteine and methionine metabolism";"Methane metabolism";"Serine biosynthesis";"Glycine, serine and threonine metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)"
Lalb_12586	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_14396	5	Reactome: R-HSA-110329;Reactome: R-HSA-9630222;Reactome: R-HSA-110328;Reactome: R-HSA-9630221;Reactome: R-HSA-110357	"Cleavage of the damaged pyrimidine";"Defective NTHL1 substrate binding";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective NTHL1 substrate processing";"Displacement of DNA glycosylase by APEX1"
Lalb_06721	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
Lalb_04048	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
Lalb_05829	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
Lalb_12342	9	Reactome: R-HSA-2173788;Reactome: R-HSA-3645790;Reactome: R-HSA-3642279;Reactome: R-HSA-2173791;Reactome: R-HSA-3304356;Reactome: R-HSA-5689603;Reactome: R-HSA-3656535;Reactome: R-HSA-2173789;Reactome: R-HSA-3656532	"Downregulation of TGF-beta receptor signaling";"TGFBR2 Kinase Domain Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"UCH proteinases";"TGFBR1 LBD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"TGFBR1 KD Mutants in Cancer"
Lalb_04576	13	Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
Lalb_07740	5	Reactome: R-HSA-5689880;KEGG: 00510+2.4.1.265;Reactome: R-HSA-4724325;Reactome: R-HSA-156581;Reactome: R-HSA-446193	"Ub-specific processing proteases";"N-Glycan biosynthesis";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"Methylation";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
Lalb_07644	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
Lalb_13077	20	Reactome: R-HSA-69091;Reactome: R-HSA-5685938;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-110314;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-5693616;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210	"Polymerase switching";"HDR through Single Strand Annealing (SSA)";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER"
Lalb_08075	2	KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921	"Histidine metabolism";"Histidine catabolism"
Lalb_10244	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
Lalb_13932	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
Lalb_01119	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_03811	5	Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-190873	"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation"
Lalb_09499	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
Lalb_05364	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
Lalb_02563	29	Reactome: R-HSA-6781827;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-5696395;Reactome: R-HSA-674695;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-6781823;Reactome: R-HSA-73863;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-167160;Reactome: R-HSA-73762	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Pre-transcription Events";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"Dual Incision in GG-NER";"Dual incision in TC-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Termination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation"
Lalb_04429	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
Lalb_13323	5	Reactome: R-HSA-199220;Reactome: R-HSA-163765;Reactome: R-HSA-9029558;Reactome: R-HSA-2426168;Reactome: R-HSA-75105	"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis"
Lalb_06438	1	Reactome: R-HSA-156588	"Glucuronidation"
Lalb_14175	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_07357	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
Lalb_00995	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
Lalb_01150	10	KEGG: 00052+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00680+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1042;KEGG: 00030+2.7.1.11;MetaCyc: PWY-5484	"Galactose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Methane metabolism";"Glycolysis";"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)"
Lalb_04579	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
Lalb_07568	56	Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-69017;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Hedgehog 'on' state";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"Degradation of AXIN";"Regulation of RAS by GAPs";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"CDK-mediated phosphorylation and removal of Cdc6";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
Lalb_04408	57	Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-9020702;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-6798695;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-382556	"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Interleukin-1 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Neutrophil degranulation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport"
Lalb_00283	5	Reactome: R-HSA-162710;Reactome: R-HSA-4717374;Reactome: R-HSA-4719360;Reactome: R-HSA-4719377;Reactome: R-HSA-162699	"Synthesis of glycosylphosphatidylinositol (GPI)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Synthesis of dolichyl-phosphate mannose"
Lalb_07384	7	Reactome: R-HSA-9018519;Reactome: R-HSA-2470946;Reactome: R-HSA-1221632;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-3108214;Reactome: R-HSA-2467813	"Estrogen-dependent gene expression";"Cohesin Loading onto Chromatin";"Meiotic synapsis";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Separation of Sister Chromatids"
Lalb_02989	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
Lalb_08647	7	Reactome: R-HSA-71064;Reactome: R-HSA-71403;KEGG: 00020+2.3.1.61;Reactome: R-HSA-389661;KEGG: 00380+2.3.1.61;MetaCyc: PWY-5084;KEGG: 00310+2.3.1.61	"Lysine catabolism";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation"
Lalb_04350	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
Lalb_01291	1	Reactome: R-HSA-525793	"Myogenesis"
Lalb_10716	3	KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619	"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI"
Lalb_03750	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
Lalb_05896	12	Reactome: R-HSA-2142789;MetaCyc: PWY-5856;KEGG: 00130+2.5.1.39;Reactome: R-HSA-1268020;MetaCyc: PWY-6708;MetaCyc: PWY-5872;MetaCyc: PWY-5871;MetaCyc: PWY-5857;MetaCyc: PWY-6978;MetaCyc: PWY-5873;MetaCyc: PWY-5855;MetaCyc: PWY-5870	"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Mitochondrial protein import";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)"
Lalb_02743	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
Lalb_13121	4	MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943	"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
Lalb_11965	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
Lalb_05024	18	Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-166208;Reactome: R-HSA-6790901;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72695	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"mTORC1-mediated signalling";"rRNA modification in the nucleus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex"
Lalb_04495	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
Lalb_06991	1	Reactome: R-HSA-419771	"Opsins"
Lalb_10040	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
Lalb_06088	1	Reactome: R-HSA-8876725	"Protein methylation"
Lalb_07590	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
Lalb_08323	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
Lalb_04416	1	Reactome: R-HSA-6783984	"Glycine degradation"
Lalb_11800	1	Reactome: R-HSA-2173788	"Downregulation of TGF-beta receptor signaling"
Lalb_05981	17	Reactome: R-HSA-6804114;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-9616222;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-2559585;Reactome: R-HSA-8953750;Reactome: R-HSA-2173796;Reactome: R-HSA-113501;Reactome: R-HSA-1362300;Reactome: R-HSA-2559580;Reactome: R-HSA-69205;Reactome: R-HSA-139915;Reactome: R-HSA-1912408;Reactome: R-HSA-69231;Reactome: R-HSA-111448	"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Transcriptional regulation of granulopoiesis";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Oncogene Induced Senescence";"Transcriptional Regulation by E2F6";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Oxidative Stress Induced Senescence";"G1/S-Specific Transcription";"Activation of PUMA and translocation to mitochondria";"Pre-NOTCH Transcription and Translation";"Cyclin D associated events in G1";"Activation of NOXA and translocation to mitochondria"
Lalb_06097	14	MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7724	"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
Lalb_02256	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
Lalb_03836	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
Lalb_04598	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
Lalb_10510	4	Reactome: R-HSA-1268020;Reactome: R-HSA-8949613;Reactome: R-HSA-3371453;Reactome: R-HSA-8950505	"Mitochondrial protein import";"Cristae formation";"Regulation of HSF1-mediated heat shock response";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
Lalb_07598	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
Lalb_09128	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
Lalb_03061	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
Lalb_08677	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
Lalb_09563	17	Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;Reactome: R-HSA-141444;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;KEGG: 04926+2.7.11.1;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9022692;KEGG: 05163+2.7.11.1	"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Human immunodeficiency virus 1 infection";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Relaxin signaling pathway";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"mTOR signaling pathway";"Regulation of MECP2 expression and activity";"Human cytomegalovirus infection"
Lalb_00705	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
Lalb_06508	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
Lalb_13876	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
Lalb_14097	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
Lalb_11187	14	Reactome: R-HSA-2979096;Reactome: R-HSA-6798695;Reactome: R-HSA-2122948;Reactome: R-HSA-1474228;Reactome: R-HSA-9013700;Reactome: R-HSA-205043;Reactome: R-HSA-2894862;Reactome: R-HSA-3928665;Reactome: R-HSA-977225;Reactome: R-HSA-9017802;Reactome: R-HSA-193692;Reactome: R-HSA-9013507;Reactome: R-HSA-1251985;Reactome: R-HSA-2644606	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Neutrophil degranulation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Degradation of the extracellular matrix";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"Amyloid fiber formation";"Noncanonical activation of NOTCH3";"Regulated proteolysis of p75NTR";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
Lalb_10248	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_03366	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
Lalb_04249	7	KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.15;KEGG: 00970+6.1.1.17;Reactome: R-HSA-6782315;Reactome: R-HSA-379716	"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol";"Cytosolic tRNA aminoacylation"
Lalb_12522	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
Lalb_12356	4	KEGG: 00513+2.4.1.260;Reactome: R-HSA-446193;Reactome: R-HSA-4720489;KEGG: 00510+2.4.1.260	"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"N-Glycan biosynthesis"
Lalb_01337	2	Reactome: R-HSA-1362409;Reactome: R-HSA-1268020	"Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import"
Lalb_07508	2	KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23	"Pyrimidine metabolism";"Drug metabolism - other enzymes"
Lalb_07603	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
Lalb_06684	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
Lalb_02252	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
Lalb_02555	5	Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;Reactome: R-HSA-163765;Reactome: R-HSA-9029558	"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis"
Lalb_11864	1	Reactome: R-HSA-189200	"Cellular hexose transport"
Lalb_00698	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
Lalb_08897	4	Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169	"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis"
Lalb_12679	33	Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-2467813;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9610379;Reactome: R-HSA-141444;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-3108214	"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Separation of Sister Chromatids";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"HCMV Late Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA damage response and repair proteins"
Lalb_14549	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
Lalb_02950	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
Lalb_05589	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-6433	"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)"
Lalb_05088	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
Lalb_08788	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
Lalb_03619	6	Reactome: R-HSA-73933;Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-73930;Reactome: R-HSA-110373;Reactome: R-HSA-110357	"Resolution of Abasic Sites (AP sites)";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Displacement of DNA glycosylase by APEX1"
Lalb_02525	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
Lalb_05159	4	Reactome: R-HSA-5620912;Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Anchoring of the basal body to the plasma membrane";"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
Lalb_08287	4	Reactome: R-HSA-112311;Reactome: R-HSA-422085;KEGG: 00564+3.1.1.7;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Glycerophospholipid metabolism";"Synthesis of PC"
Lalb_11835	2	Reactome: R-HSA-1268020;Reactome: R-HSA-71403	"Mitochondrial protein import";"Citric acid cycle (TCA cycle)"
Lalb_00822	8	Reactome: R-HSA-68952;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-174411	"DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Removal of the Flap Intermediate";"Polymerase switching";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere"
Lalb_07433	10	Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-9018519	"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Estrogen-dependent gene expression"
Lalb_01494	4	Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
Lalb_08456	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
Lalb_00993	4	MetaCyc: PWY-7807;MetaCyc: PWY-7805;Reactome: R-HSA-71737;KEGG: 00190+3.6.1.1	"Glyphosate degradation III";"(aminomethyl)phosphonate degradation";"Pyrophosphate hydrolysis";"Oxidative phosphorylation"
Lalb_02050	4	Reactome: R-HSA-446193;KEGG: 00513+2.4.1.258;KEGG: 00510+2.4.1.258;Reactome: R-HSA-4720475	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Defective ALG3 causes ALG3-CDG (CDG-1d)"
Lalb_10698	6	Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex"
Lalb_04614	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
Lalb_13955	3	Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-6807505	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes"
Lalb_13300	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
Lalb_11426	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import"
Lalb_00892	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
Lalb_03373	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
Lalb_01132	1	Reactome: R-HSA-5635838	"Activation of SMO"
Lalb_04431	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
Lalb_01786	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
Lalb_03292	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
Lalb_11684	9	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection"
Lalb_12236	5	Reactome: R-HSA-432720;Reactome: R-HSA-2206305;KEGG: 00531+3.1.6.14;Reactome: R-HSA-2022857;Reactome: R-HSA-6798695	"Lysosome Vesicle Biogenesis";"MPS IIID - Sanfilippo syndrome D";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Neutrophil degranulation"
Lalb_11282	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
Lalb_02494	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
Lalb_12167	16	Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72706	"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit"
Lalb_13986	1	Reactome: R-HSA-191859	"snRNP Assembly"
Lalb_00543	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
Lalb_00720	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
Lalb_09894	1	Reactome: R-HSA-156588	"Glucuronidation"
Lalb_08162	7	KEGG: 00240+6.3.5.5;MetaCyc: PWY-7791;MetaCyc: PWY-5154;MetaCyc: PWY-7790;MetaCyc: PWY-5686;MetaCyc: PWY-7400;KEGG: 00250+6.3.5.5	"Pyrimidine metabolism";"UMP biosynthesis III";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"UMP biosynthesis II";"UMP biosynthesis I";"L-arginine biosynthesis IV (archaebacteria)";"Alanine, aspartate and glutamate metabolism"
Lalb_10168	18	MetaCyc: PWY-7224;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;Reactome: R-HSA-499943;MetaCyc: PWY-7227;MetaCyc: PWY-6545;MetaCyc: PWY-7226;MetaCyc: PWY-7184;MetaCyc: PWY-7220;MetaCyc: PWY-7205;MetaCyc: PWY-7210;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7221;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7197	"Purine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation"
Lalb_10732	2	KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
Lalb_08683	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
Lalb_06459	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
Lalb_11977	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
Lalb_08650	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-76071	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
Lalb_11617	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
Lalb_04004	13	Reactome: R-HSA-8948216;Reactome: R-HSA-2214320;Reactome: R-HSA-2022090;Reactome: R-HSA-3000171;Reactome: R-HSA-1474244;Reactome: R-HSA-186797;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2243919;Reactome: R-HSA-419037;Reactome: R-HSA-3000157;Reactome: R-HSA-3000178;Reactome: R-HSA-216083	"Collagen chain trimerization";"Anchoring fibril formation";"Assembly of collagen fibrils and other multimeric structures";"Non-integrin membrane-ECM interactions";"Extracellular matrix organization";"Signaling by PDGF";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Crosslinking of collagen fibrils";"NCAM1 interactions";"Laminin interactions";"ECM proteoglycans";"Integrin cell surface interactions"
Lalb_04118	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
Lalb_01895	3	KEGG: 00970+6.1.1.14;Reactome: R-HSA-379726;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation"
Lalb_01015	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
Lalb_08830	13	KEGG: 00740+3.6.1.9;KEGG: 00240+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.9;Reactome: R-HSA-74259;MetaCyc: PWY-7184;MetaCyc: PWY-7821;KEGG: 00770+3.6.1.9;KEGG: 00230+3.6.1.66;MetaCyc: PWY-7187;MetaCyc: PWY-7206;KEGG: 00500+3.6.1.9;KEGG: 00760+3.6.1.9	"Riboflavin metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Purine catabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Tunicamycin biosynthesis";"Pantothenate and CoA biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides dephosphorylation";"Starch and sucrose metabolism";"Nicotinate and nicotinamide metabolism"
Lalb_03687	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
Lalb_01517	3	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis"
Lalb_06325	5	Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling"
Lalb_02766	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_02271	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
Lalb_11228	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
Lalb_06664	1	Reactome: R-HSA-5250924	"B-WICH complex positively regulates rRNA expression"
Lalb_03635	2	Reactome: R-HSA-8939243;Reactome: R-HSA-8953750	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional Regulation by E2F6"
Lalb_06562	5	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.10;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
Lalb_00468	6	Reactome: R-HSA-2426168;KEGG: 00900+4.1.1.33;MetaCyc: PWY-922;MetaCyc: PWY-7391;Reactome: R-HSA-446199;Reactome: R-HSA-191273	"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Synthesis of Dolichyl-phosphate";"Cholesterol biosynthesis"
Lalb_05484	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
Lalb_04164	1	Reactome: R-HSA-8951664	"Neddylation"
Lalb_12036	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
Lalb_10661	5	Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556	"Amino acids regulate mTORC1";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes"
Lalb_01586	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
Lalb_12902	3	Reactome: R-HSA-947581;KEGG: 00790+2.10.1.1;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
Lalb_04981	31	MetaCyc: PWY-5366;MetaCyc: PWY-8049;MetaCyc: PWY-5367;MetaCyc: PWY-7858;MetaCyc: PWY-5142;MetaCyc: PWY-5994;Reactome: R-HSA-9029558;MetaCyc: PWY-6519;Reactome: R-HSA-75105;MetaCyc: PWY-7388;MetaCyc: PWY-8012;MetaCyc: PWYG-321;MetaCyc: PWY-7746;MetaCyc: PWY-6799;Reactome: R-HSA-163765;MetaCyc: PWY-8047;MetaCyc: PWY-5989;MetaCyc: PWY-5147;MetaCyc: PWY-7663;Reactome: R-HSA-2426168;MetaCyc: PWY-4381;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5966-1;Reactome: R-HSA-199220;MetaCyc: PWY-5971;MetaCyc: PWY-7664;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6282;MetaCyc: PWY-7723;MetaCyc: PWY-6113;MetaCyc: PWY-5973	"Palmitoleate biosynthesis II (plants and bacteria)";"Pederin biosynthesis";"Petroselinate biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Acyl-[acyl-carrier protein] thioesterase pathway";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"8-amino-7-oxononanoate biosynthesis I";"Fatty acyl-CoA biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Mupirocin biosynthesis";"";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"ChREBP activates metabolic gene expression";"Bryostatin biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Oleate biosynthesis I (plants)";"Gondoate biosynthesis (anaerobic)";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Oleate biosynthesis IV (anaerobic)";"Biotin metabolism";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Bacterial bioluminescence";"Superpathway of mycolate biosynthesis";"Cis-vaccenate biosynthesis"
Lalb_12346	5	Reactome: R-HSA-72187;Reactome: R-HSA-6784531;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"mRNA 3'-end processing";"tRNA processing in the nucleus";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
Lalb_01474	11	KEGG: 04151+2.7.11.1;Reactome: R-HSA-1834949;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-8866654;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Cytosolic sensors of pathogen-associated DNA";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"E3 ubiquitin ligases ubiquitinate target proteins";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
Lalb_13113	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
Lalb_01922	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
Lalb_11509	2	Reactome: R-HSA-2022377;Reactome: R-HSA-6798695	"Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation"
Lalb_01917	5	Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-174490	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Budding and maturation of HIV virion";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins"
Lalb_12715	6	KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817	"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)"
Lalb_07941	2	Reactome: R-HSA-5658442;Reactome: R-HSA-6802953	"Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants"
Lalb_09934	4	KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614	"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage"
Lalb_07803	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
Lalb_14416	10	Reactome: R-HSA-611105;Reactome: R-HSA-5628897;Reactome: R-HSA-3299685;Reactome: R-HSA-111464;Reactome: R-HSA-111463;Reactome: R-HSA-111459;Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-2151201;Reactome: R-HSA-111457	"Respiratory electron transport";"TP53 Regulates Metabolic Genes";"Detoxification of Reactive Oxygen Species";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC (DIABLO) binds to IAPs";"Activation of caspases through apoptosome-mediated cleavage";"Regulation of the apoptosome activity";"Formation of apoptosome";"Transcriptional activation of mitochondrial biogenesis";"Release of apoptotic factors from the mitochondria"
Lalb_01627	1	Reactome: R-HSA-189200	"Cellular hexose transport"
Lalb_04356	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
Lalb_01535	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
Lalb_11006	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
Lalb_01339	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
Lalb_05160	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
Lalb_06343	56	Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-69017;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-180534	"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"Degradation of AXIN";"Regulation of RAS by GAPs";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"CDK-mediated phosphorylation and removal of Cdc6";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4"
Lalb_11227	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
Lalb_01715	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
Lalb_03517	1	Reactome: R-HSA-1632852	"Macroautophagy"
Lalb_14113	7	MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7185;MetaCyc: PWY-7198;KEGG: 00230+3.6.1.15;KEGG: 00730+3.6.1.15	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Thiamine metabolism"
Lalb_07699	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
Lalb_11328	5	Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-430039	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 5' to 3' exoribonuclease"
Lalb_13708	4	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
Lalb_03101	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
Lalb_02940	52	Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-5578749;Reactome: R-HSA-203927;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-73863;Reactome: R-HSA-112382;Reactome: R-HSA-5601884;Reactome: R-HSA-167290;Reactome: R-HSA-6781827;Reactome: R-HSA-749476;Reactome: R-HSA-674695;Reactome: R-HSA-73780;Reactome: R-HSA-77075;Reactome: R-HSA-9018519;Reactome: R-HSA-72086;Reactome: R-HSA-6807505;Reactome: R-HSA-73762;Reactome: R-HSA-72163;Reactome: R-HSA-5250924;Reactome: R-HSA-76071;Reactome: R-HSA-76042;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-6782210;Reactome: R-HSA-72203;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-73772;Reactome: R-HSA-6782135;Reactome: R-HSA-1834949;Reactome: R-HSA-167238;Reactome: R-HSA-6781823;Reactome: R-HSA-6803529;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-76061;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-168325;Reactome: R-HSA-167162;Reactome: R-HSA-427413;Reactome: R-HSA-5617472	"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"Transcriptional regulation by small RNAs";"MicroRNA (miRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Termination";"Formation of RNA Pol II elongation complex";"PIWI-interacting RNA (piRNA) biogenesis";"Pausing and recovery of HIV elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase III Chain Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Estrogen-dependent gene expression";"mRNA Capping";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase I Transcription Initiation";"mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processing of Capped Intron-Containing Pre-mRNA";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Promoter Escape";"Dual incision in TC-NER";"Cytosolic sensors of pathogen-associated DNA";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of TC-NER Pre-Incision Complex";"FGFR2 alternative splicing";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Viral Messenger RNA Synthesis";"RNA Polymerase II HIV Promoter Escape";"NoRC negatively regulates rRNA expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
Lalb_12163	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_00937	7	Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025	"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation"
Lalb_09796	7	Reactome: R-HSA-1660662;MetaCyc: PWY-7836;MetaCyc: PWY-5129;MetaCyc: PWY-7841;MetaCyc: PWY-7838;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7839	"Glycosphingolipid metabolism";"Ganglio-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Neolacto-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Lacto-series glycosphingolipids biosynthesis"
Lalb_11167	7	Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-8869496;Reactome: R-HSA-390471;Reactome: R-HSA-1268020;Reactome: R-HSA-6814122	"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Association of TriC/CCT with target proteins during biosynthesis";"Mitochondrial protein import";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
Lalb_03076	1	Reactome: R-HSA-189200	"Cellular hexose transport"
Lalb_00617	6	Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-5632684;Reactome: R-HSA-201722;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"Hedgehog 'on' state";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
Lalb_05327	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
Lalb_08351	3	Reactome: R-HSA-6787639;Reactome: R-HSA-5619078;Reactome: R-HSA-727802	"GDP-fucose biosynthesis";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)";"Transport of nucleotide sugars"
Lalb_08601	1	Reactome: R-HSA-420029	"Tight junction interactions"
Lalb_06933	6	Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-389957	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC"
Lalb_04941	2	Reactome: R-HSA-70895;KEGG: 00280+1.3.8.4	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
Lalb_00622	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
Lalb_09644	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
Lalb_13398	5	Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-176974	"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Unwinding of DNA"
Lalb_06023	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
Lalb_10534	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
Lalb_03189	7	Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259	"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes"
Lalb_00560	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
Lalb_07905	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
Lalb_08935	14	MetaCyc: PWY-7589;MetaCyc: PWY-7782;MetaCyc: PWY-8051;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-8055	"Palmitoleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Anandamide biosynthesis II";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis"
Lalb_04846	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
Lalb_07816	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
Lalb_04197	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_07939	29	Reactome: R-HSA-73762;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-167161;Reactome: R-HSA-73863;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-5696395;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-6781827;Reactome: R-HSA-75955	"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"HIV Transcription Initiation";"RNA Polymerase I Transcription Termination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"Dual incision in TC-NER";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Elongation"
Lalb_03663	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
Lalb_07574	1	Reactome: R-HSA-189200	"Cellular hexose transport"
Lalb_13896	13	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-2408557	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Selenocysteine synthesis"
Lalb_11256	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
Lalb_14184	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
Lalb_05673	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
Lalb_07278	12	KEGG: 04660+3.1.3.16;Reactome: R-HSA-2467813;Reactome: R-HSA-400253;Reactome: R-HSA-2173788;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-141444	"T cell receptor signaling pathway";"Separation of Sister Chromatids";"Circadian Clock";"Downregulation of TGF-beta receptor signaling";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
Lalb_06931	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
Lalb_01716	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
Lalb_01483	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
Lalb_11949	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
Lalb_08878	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
Lalb_10799	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_01613	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
Lalb_13969	16	Reactome: R-HSA-983168;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-176407;Reactome: R-HSA-176408;Reactome: R-HSA-174184	"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
Lalb_03407	5	KEGG: 04070+3.1.3.64;MetaCyc: PWY-6580;KEGG: 00562+3.1.3.64;Reactome: R-HSA-1660499;MetaCyc: PWY-6368	"Phosphatidylinositol signaling system";"Phosphatidylinositol biosynthesis I (bacteria)";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation"
Lalb_05989	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
Lalb_07552	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
Lalb_02116	24	Reactome: R-HSA-2467813;Reactome: R-HSA-437239;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736	"Separation of Sister Chromatids";"Recycling pathway of L1";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"Activation of AMPK downstream of NMDARs";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors"
Lalb_10512	14	Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-110320;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-110312	"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH";"Translesion synthesis by POLK";"Translesion synthesis by POLI";"Translesion synthesis by REV1"
Lalb_08362	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
Lalb_00046	13	MetaCyc: PWY-7210;MetaCyc: PWY-7222;KEGG: 00230+1.17.4.1;KEGG: 00983+1.17.4.1;KEGG: 00480+1.17.4.1;Reactome: R-HSA-499943;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7184;MetaCyc: PWY-7226;MetaCyc: PWY-6545;MetaCyc: PWY-7227;MetaCyc: PWY-7220	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Drug metabolism - other enzymes";"Glutathione metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II"
Lalb_08034	17	Reactome: R-HSA-5358565;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-69166;Reactome: R-HSA-110314;Reactome: R-HSA-174414;Reactome: R-HSA-5358606;Reactome: R-HSA-174437;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-174417;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate";"Recognition of DNA damage by PCNA-containing replication complex";"Processive synthesis on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Removal of the Flap Intermediate from the C-strand";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Processive synthesis on the lagging strand";"Telomere C-strand (Lagging Strand) Synthesis";"Dual Incision in GG-NER";"Dual incision in TC-NER"
Lalb_11428	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
Lalb_11548	1	Reactome: R-HSA-156588	"Glucuronidation"
Lalb_03552	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
Lalb_06125	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_08747	8	Reactome: R-HSA-917977;Reactome: R-HSA-983712;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;KEGG: 00195+7.1.2.2;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"Ion channel transport";"Oxidative phosphorylation";"ATP biosynthesis";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Photosynthesis";"Amino acids regulate mTORC1"
Lalb_00987	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
Lalb_03417	1	Reactome: R-HSA-419037	"NCAM1 interactions"
Lalb_04489	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
Lalb_09201	9	Reactome: R-HSA-6794361;Reactome: R-HSA-8849932;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-3928662;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-438066	"Neurexins and neuroligins";"Synaptic adhesion-like molecules";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"EPHB-mediated forward signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation"
Lalb_12243	16	Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-1799339	"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane"
Lalb_11470	1	Reactome: R-HSA-6798163	"Choline catabolism"
Lalb_10363	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
Lalb_08714	16	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-156827	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression"
Lalb_08773	16	Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72695	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex"
Lalb_02097	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
Lalb_05819	3	Reactome: R-HSA-6798695;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Neutrophil degranulation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_12732	6	Reactome: R-HSA-111367;Reactome: R-HSA-72165;Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-191859;Reactome: R-HSA-72163	"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"snRNP Assembly";"mRNA Splicing - Major Pathway"
Lalb_10407	7	Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363	"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"Phytate degradation I";"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation"
Lalb_06094	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
Lalb_00418	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
Lalb_07958	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
Lalb_03779	42	Reactome: R-HSA-1221632;Reactome: R-HSA-3214847;Reactome: R-HSA-9616222;Reactome: R-HSA-912446;Reactome: R-HSA-9018519;Reactome: R-HSA-5693571;Reactome: R-HSA-8939236;Reactome: R-HSA-3214815;Reactome: R-HSA-2559582;Reactome: R-HSA-73728;Reactome: R-HSA-5578749;Reactome: R-HSA-427389;Reactome: R-HSA-1912408;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-427359;Reactome: R-HSA-171306;Reactome: R-HSA-5693565;Reactome: R-HSA-5625886;Reactome: R-HSA-5334118;Reactome: R-HSA-110329;Reactome: R-HSA-3214841;Reactome: R-HSA-73772;Reactome: R-HSA-201722;Reactome: R-HSA-427413;Reactome: R-HSA-5617472;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-977225;Reactome: R-HSA-8936459;Reactome: R-HSA-212300;Reactome: R-HSA-5250924;Reactome: R-HSA-2299718;Reactome: R-HSA-110330;Reactome: R-HSA-2559580;Reactome: R-HSA-2559586;Reactome: R-HSA-110331;Reactome: R-HSA-110328;Reactome: R-HSA-606279;Reactome: R-HSA-3214842;Reactome: R-HSA-9610379;Reactome: R-HSA-3214858	"Meiotic synapsis";"HATs acetylate histones";"Transcriptional regulation of granulopoiesis";"Meiotic recombination";"Estrogen-dependent gene expression";"Nonhomologous End-Joining (NHEJ)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDACs deacetylate histones";"Senescence-Associated Secretory Phenotype (SASP)";"RNA Polymerase I Promoter Opening";"Transcriptional regulation by small RNAs";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Pre-NOTCH Transcription and Translation";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"SIRT1 negatively regulates rRNA expression";"Packaging Of Telomere Ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"DNA methylation";"Cleavage of the damaged pyrimidine";"PKMTs methylate histone lysines";"RNA Polymerase I Promoter Escape";"Formation of the beta-catenin:TCF transactivating complex";"NoRC negatively regulates rRNA expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Amyloid fiber formation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PRC2 methylates histones and DNA";"B-WICH complex positively regulates rRNA expression";"Condensation of Prophase Chromosomes";"Recognition and association of DNA glycosylase with site containing an affected purine";"Oxidative Stress Induced Senescence";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Deposition of new CENPA-containing nucleosomes at the centromere";"HDMs demethylate histones";"HCMV Late Events";"RMTs methylate histone arginines"
Lalb_12716	4	MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17;Reactome: R-HSA-379726	"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
Lalb_07615	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
Lalb_09807	1	Reactome: R-HSA-1632852	"Macroautophagy"
Lalb_06632	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
Lalb_03286	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
Lalb_01691	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
Lalb_12294	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
Lalb_00534	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
Lalb_05346	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
Lalb_09504	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
Lalb_11592	5	Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-5689901	"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs"
Lalb_08077	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-68884	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Mitotic Telophase/Cytokinesis"
Lalb_05919	1	Reactome: R-HSA-71384	"Ethanol oxidation"
Lalb_06174	3	MetaCyc: PWY-5996;Reactome: R-HSA-75105;MetaCyc: PWY-5987	"Oleate biosynthesis II (animals and fungi)";"Fatty acyl-CoA biosynthesis";"Sorgoleone biosynthesis"
Lalb_04422	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
Lalb_00332	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
Lalb_06791	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
Lalb_01115	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
Lalb_08834	56	Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-174184	"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
Lalb_13499	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
Lalb_13648	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
Lalb_10261	2	Reactome: R-HSA-416482;Reactome: R-HSA-456926	"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)"
Lalb_12719	1	Reactome: R-HSA-8876725	"Protein methylation"
Lalb_08120	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
Lalb_08022	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
Lalb_14005	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
Lalb_00154	6	Reactome: R-HSA-3322077;MetaCyc: PWY-622;MetaCyc: PWY-5067;Reactome: R-HSA-3878781;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18	"Glycogen synthesis";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen storage disease type IV (GBE1)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism"
Lalb_07689	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
Lalb_04984	6	Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-5250924	"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression"
Lalb_12208	6	Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion"
Lalb_01973	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
Lalb_13670	3	Reactome: R-HSA-6785807;Reactome: R-HSA-8939902;Reactome: R-HSA-8878166	"Interleukin-4 and Interleukin-13 signaling";"Regulation of RUNX2 expression and activity";"Transcriptional regulation by RUNX2"
Lalb_05991	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
Lalb_11053	60	KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.211;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6946;KEGG: 00310+4.2.1.17+1.1.1.35;Reactome: R-HSA-77310;MetaCyc: PWY-7726;MetaCyc: PWY-6883;KEGG: 00281+4.2.1.17;Reactome: R-HSA-77350;Reactome: R-HSA-77348;Reactome: R-HSA-77346;MetaCyc: PWY-7094;MetaCyc: PWY-5789;MetaCyc: PWY-5177;KEGG: 00720+4.2.1.17;MetaCyc: PWY-6435;MetaCyc: PWY-6945;MetaCyc: PWY-1361;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7216;Reactome: R-HSA-77288;MetaCyc: PWY-7778;KEGG: 00362+4.2.1.17;KEGG: 00930+4.2.1.17;KEGG: 00650+4.2.1.17;MetaCyc: PWY-7606;KEGG: 00640+4.2.1.17;MetaCyc: PWY-6863;MetaCyc: PWY-5109;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17;MetaCyc: PWY-5138;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.211;KEGG: 00360+4.2.1.17;KEGG: 00592+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17;KEGG: 00903+4.2.1.17;MetaCyc: PWY-5136;Reactome: R-HSA-77305;MetaCyc: PWY-7401;MetaCyc: PWY-7007;MetaCyc: PWY-6583;MetaCyc: PWY-7654;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;Reactome: R-HSA-77285;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;Reactome: R-HSA-1482798;KEGG: 00280+4.2.1.17;MetaCyc: PWY-6944	"Butanoate metabolism";"Carbon fixation pathways in prokaryotes";"Fatty acid elongation";"Aminobenzoate degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Lysine degradation";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Pyruvate fermentation to butanol II (engineered)";"Geraniol degradation";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Fatty acid salvage";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glutaryl-coa degradation";"Carbon fixation pathways in prokaryotes";"4-hydroxybenzoate biosynthesis III (plants)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Benzoyl-coa degradation I (aerobic)";"beta-Alanine metabolism";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"2-methylpropene degradation";"Benzoate degradation";"Caprolactam degradation";"Butanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"Pyruvate fermentation to hexanol (engineered)";"Fermentation to 2-methylbutanoate";"Butanoate metabolism";"Methyl tert-butyl ether degradation";"Fatty acid degradation";"Tryptophan metabolism";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Valine, leucine and isoleucine degradation";"Toluene degradation";"Fatty acid elongation";"Fatty acid degradation";"Phenylalanine metabolism";"alpha-Linolenic acid metabolism";"Geraniol degradation";"Lysine degradation";"Limonene and pinene degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Methyl ketone biosynthesis (engineered)";"Pyruvate fermentation to butanol I";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Tryptophan metabolism";"Benzoate degradation";"Spodoptera littoralis pheromone biosynthesis";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Caprolactam degradation";"Fatty acid degradation";"Acyl chain remodeling of CL";"Valine, leucine and isoleucine degradation";"Androstenedione degradation"
Lalb_05940	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
Lalb_08813	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_06002	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
Lalb_08275	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
Lalb_14068	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
Lalb_02966	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
Lalb_14381	1	Reactome: R-HSA-71288	"Creatine metabolism"
Lalb_13865	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
Lalb_09686	10	Reactome: R-HSA-163680;Reactome: R-HSA-5628897;Reactome: R-HSA-9613354;Reactome: R-HSA-2151209;Reactome: R-HSA-1632852;Reactome: R-HSA-1445148;Reactome: R-HSA-380972;Reactome: R-HSA-9619483;Reactome: R-HSA-200425;Reactome: R-HSA-6804756	"AMPK inhibits chREBP transcriptional activation activity";"TP53 Regulates Metabolic Genes";"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Macroautophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs";"Carnitine metabolism";"Regulation of TP53 Activity through Phosphorylation"
Lalb_08138	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
Lalb_04337	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
Lalb_06373	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
Lalb_05722	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
Lalb_07356	8	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-167590;Reactome: R-HSA-9636467;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-182218	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Nef Mediated CD4 Down-regulation";"Blockage of phagosome acidification";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"Nef Mediated CD8 Down-regulation"
Lalb_03688	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
Lalb_06169	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
Lalb_11815	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_10637	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
Lalb_00588	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
Lalb_11948	5	Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310	"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway"
Lalb_14597	1	Reactome: R-HSA-5689603	"UCH proteinases"
Lalb_07604	4	MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;Reactome: R-HSA-156581	"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"Methylation"
Lalb_08367	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
Lalb_08625	6	Reactome: R-HSA-3214815;Reactome: R-HSA-1989781;Reactome: R-HSA-9022692;Reactome: R-HSA-9022537;Reactome: R-HSA-9609690;Reactome: R-HSA-9029569	"HDACs deacetylate histones";"PPARA activates gene expression";"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"HCMV Early Events";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
Lalb_02328	7	Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
Lalb_08513	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
Lalb_09103	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
Lalb_11460	6	Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit"
Lalb_02993	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
Lalb_11220	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
Lalb_07447	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_00678	1	Reactome: R-HSA-373753	"Nephrin family interactions"
Lalb_07145	3	Reactome: R-HSA-8951664;Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"Neddylation";"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_07064	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
Lalb_05782	5	Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-73772	"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape"
Lalb_02153	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
Lalb_14359	4	MetaCyc: PWY-7219;KEGG: 00250+6.3.4.4;KEGG: 00230+6.3.4.4;Reactome: R-HSA-73817	"Adenosine ribonucleotides de novo biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis"
Lalb_01597	2	KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668	"Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
Lalb_07311	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
Lalb_14152	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
Lalb_07288	4	Reactome: R-HSA-983231;Reactome: R-HSA-2586552;Reactome: R-HSA-982772;Reactome: R-HSA-1170546	"Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin";"Growth hormone receptor signaling";"Prolactin receptor signaling"
Lalb_11680	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
Lalb_07215	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
Lalb_02854	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
Lalb_08477	21	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7224;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7187;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7197;MetaCyc: PWY-7219;MetaCyc: PWY-7221;MetaCyc: PWY-7222;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7205;MetaCyc: PWY-7226;MetaCyc: PWY-6545;MetaCyc: PWY-7227;MetaCyc: PWY-7184	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Purine deoxyribonucleosides salvage";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Adenosine ribonucleotides de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
Lalb_03925	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
Lalb_14008	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
Lalb_12001	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
Lalb_01981	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_13164	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
Lalb_04798	4	MetaCyc: PWY-6557;KEGG: 00532+2.4.2.26;KEGG: 00534+2.4.2.26;Reactome: R-HSA-1971475	"Glycosaminoglycan-protein linkage region biosynthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"A tetrasaccharide linker sequence is required for GAG synthesis"
Lalb_06925	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
Lalb_05301	7	Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300	"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
Lalb_11944	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
Lalb_03350	33	Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-5619107;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-2467813;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-3108214;Reactome: R-HSA-141444;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Separation of Sister Chromatids";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA damage response and repair proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
Lalb_03030	3	Reactome: R-HSA-2206296;Reactome: R-HSA-2024101;Reactome: R-HSA-2024096	"MPS II - Hunter syndrome";"CS/DS degradation";"HS-GAG degradation"
Lalb_10266	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
Lalb_02747	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
Lalb_11190	16	Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72695	"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex"
Lalb_10107	1	Reactome: R-HSA-5676934	"Protein repair"
Lalb_09935	3	MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757	"Folate polyglutamylation";"Folate biosynthesis";"Metabolism of folate and pterines"
Lalb_10296	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
Lalb_00716	7	Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-165159	"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling"
Lalb_05002	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
Lalb_03467	1	Reactome: R-HSA-189200	"Cellular hexose transport"
Lalb_08917	2	Reactome: R-HSA-5632681;Reactome: R-HSA-5635838	"Ligand-receptor interactions";"Activation of SMO"
Lalb_03656	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
Lalb_10786	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
Lalb_01164	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
Lalb_09609	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
Lalb_11239	52	Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-8851708;Reactome: R-HSA-73779;Reactome: R-HSA-73863;Reactome: R-HSA-167160;Reactome: R-HSA-203927;Reactome: R-HSA-5578749;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-73780;Reactome: R-HSA-6781827;Reactome: R-HSA-749476;Reactome: R-HSA-167290;Reactome: R-HSA-5601884;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-72203;Reactome: R-HSA-6782210;Reactome: R-HSA-5250924;Reactome: R-HSA-72163;Reactome: R-HSA-73762;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-76042;Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-167152;Reactome: R-HSA-73980;Reactome: R-HSA-167242;Reactome: R-HSA-5617472;Reactome: R-HSA-167162;Reactome: R-HSA-168325;Reactome: R-HSA-427413;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-6803529;Reactome: R-HSA-73776;Reactome: R-HSA-1834949;Reactome: R-HSA-6782135;Reactome: R-HSA-73772;Reactome: R-HSA-167238	"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"MicroRNA (miRNA) biogenesis";"Transcriptional regulation by small RNAs";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase III Chain Elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Abortive And Retractive Initiation";"Pausing and recovery of HIV elongation";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA";"Gap-filling DNA repair synthesis and ligation in TC-NER";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway";"RNA Polymerase I Transcription Initiation";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase III Transcription Termination";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II HIV Promoter Escape";"Viral Messenger RNA Synthesis";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"FGFR2 alternative splicing";"RNA Polymerase II Promoter Escape";"Cytosolic sensors of pathogen-associated DNA";"Dual incision in TC-NER";"RNA Polymerase I Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation"
Lalb_05458	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
Lalb_10238	5	Reactome: R-HSA-373080;Reactome: R-HSA-5620922;Reactome: R-HSA-5635838;Reactome: R-HSA-5632684;Reactome: R-HSA-5610787	"Class B/2 (Secretin family receptors)";"BBSome-mediated cargo-targeting to cilium";"Activation of SMO";"Hedgehog 'on' state";"Hedgehog 'off' state"
Lalb_12856	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
Lalb_08522	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
Lalb_08679	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
Lalb_12677	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
Lalb_06898	1	Reactome: R-HSA-417973	"Adenosine P1 receptors"
Lalb_13563	16	Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;Reactome: R-HSA-72706;Reactome: R-HSA-192823;MetaCyc: PWY-4361;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-1799339	"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane"
Lalb_11970	7	Reactome: R-HSA-4570571;Reactome: R-HSA-917937;KEGG: 00630+4.2.1.3;Reactome: R-HSA-446193;KEGG: 00720+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33	"Defective RFT1 causes RFT1-CDG (CDG-1n)";"Iron uptake and transport";"Glyoxylate and dicarboxylate metabolism";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis"
Lalb_10934	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
Lalb_02709	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
Lalb_05011	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
Lalb_09910	8	Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68689	"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex"
Lalb_03575	6	Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins"
Lalb_11327	4	KEGG: 00860+1.14.14.18;MetaCyc: PWY-5874;Reactome: R-HSA-189483;Reactome: R-HSA-917937	"Porphyrin and chlorophyll metabolism";"Heme degradation I";"Heme degradation";"Iron uptake and transport"
Lalb_02916	2	Reactome: R-HSA-9020702;Reactome: R-HSA-6798695	"Interleukin-1 signaling";"Neutrophil degranulation"
Lalb_06408	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
Lalb_13924	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
Lalb_08567	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
Lalb_11796	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
Lalb_00436	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
Lalb_07051	6	Reactome: R-HSA-162594;Reactome: R-HSA-174437;Reactome: R-HSA-69166;Reactome: R-HSA-5685939;Reactome: R-HSA-5651801;Reactome: R-HSA-110362	"Early Phase of HIV Life Cycle";"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate";"HDR through MMEJ (alt-NHEJ)";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair"
Lalb_07315	9	Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942	"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)"
Lalb_01959	4	Reactome: R-HSA-499943;Reactome: R-HSA-6798695;KEGG: 00590+5.3.99.3;Reactome: R-HSA-2162123	"Interconversion of nucleotide di- and triphosphates";"Neutrophil degranulation";"Arachidonic acid metabolism";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)"
Lalb_04683	4	Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
Lalb_04623	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
Lalb_05917	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
Lalb_01297	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
Lalb_07209	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
Lalb_02629	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
Lalb_13309	5	MetaCyc: PWY-7536;MetaCyc: PWY-5189;KEGG: 00860+2.3.1.37;Reactome: R-HSA-189451;KEGG: 00260+2.3.1.37	"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Glycine, serine and threonine metabolism"
Lalb_00550	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
Lalb_01900	2	Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
Lalb_12201	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
Lalb_01007	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
Lalb_07243	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
Lalb_03755	5	Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-5689880;MetaCyc: PWY-7511	"Regulation of PTEN stability and activity";"Degradation of AXIN";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Protein ubiquitination"
Lalb_13978	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
Lalb_01828	2	Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
Lalb_14318	10	Reactome: R-HSA-8849932;Reactome: R-HSA-447038;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-451308;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-442982	"Synaptic adhesion-like molecules";"NrCAM interactions";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Activation of Ca-permeable Kainate Receptor";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor"
Lalb_10198	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
Lalb_01405	1	Reactome: R-HSA-189200	"Cellular hexose transport"
Lalb_07233	1	Reactome: R-HSA-189200	"Cellular hexose transport"
Lalb_03661	8	Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-6798695;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-9639288	"Macroautophagy";"TP53 Regulates Metabolic Genes";"Neutrophil degranulation";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Amino acids regulate mTORC1"
Lalb_14131	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
Lalb_02902	6	Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
Lalb_12207	1	Reactome: R-HSA-5626467	"RHO GTPases activate IQGAPs"
Lalb_06126	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
Lalb_12598	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
Lalb_06473	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
Lalb_01806	3	MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-1358803	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling"
Lalb_04977	18	KEGG: 00590+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7409;MetaCyc: PWY-6803;Reactome: R-HSA-1482801;Reactome: R-HSA-1482925;MetaCyc: PWY-8051;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417	"Arachidonic acid metabolism";"Synthesis of PA";"Anandamide biosynthesis II";"Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PS";"Acyl chain remodelling of PG";"Anandamide biosynthesis I";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)"
Lalb_10856	4	Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946	"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin"
Lalb_13131	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
Lalb_14737	1	KEGG: 00970+6.1.1.14	"Aminoacyl-tRNA biosynthesis"
Lalb_03158	14	Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167238	"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation"
Lalb_11000	13	KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;Reactome: R-HSA-2022857;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662	"Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Other glycan degradation";"Glycosphingolipid metabolism"
Lalb_00227	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
Lalb_10415	2	KEGG: 00260+1.4.4.2;Reactome: R-HSA-6783984	"Glycine, serine and threonine metabolism";"Glycine degradation"
Lalb_05597	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
Lalb_02584	6	Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702	"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition"
Lalb_08919	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
Lalb_02867	8	MetaCyc: PWY-6580;MetaCyc: PWY-6664;Reactome: R-HSA-1855183;KEGG: 00521+5.5.1.4;MetaCyc: PWY-6372;MetaCyc: PWY-4661;MetaCyc: PWY-2301;KEGG: 00562+5.5.1.4	"Phosphatidylinositol biosynthesis I (bacteria)";"Di-myo-inositol phosphate biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Myo-inositol biosynthesis";"Inositol phosphate metabolism"
Lalb_14519	7	KEGG: 00240+6.3.5.5;MetaCyc: PWY-7791;MetaCyc: PWY-7400;KEGG: 00250+6.3.5.5;MetaCyc: PWY-5154;MetaCyc: PWY-7790;MetaCyc: PWY-5686	"Pyrimidine metabolism";"UMP biosynthesis III";"L-arginine biosynthesis IV (archaebacteria)";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"UMP biosynthesis II";"UMP biosynthesis I"
Lalb_03342	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
Lalb_10988	8	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
Lalb_04688	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_02883	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
Lalb_01422	4	Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395	"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER"
Lalb_14217	8	MetaCyc: PWY-5;KEGG: 00220+6.3.4.5;Reactome: R-HSA-70635;MetaCyc: PWY-4983;MetaCyc: PWY-5154;KEGG: 00250+6.3.4.5;MetaCyc: PWY-4984;MetaCyc: PWY-7400	"Canavanine biosynthesis";"Arginine biosynthesis";"Urea cycle";"Nitric oxide biosynthesis II (mammals)";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"Urea cycle";"L-arginine biosynthesis IV (archaebacteria)"
Lalb_03981	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
Lalb_07600	27	Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-165054	"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"snRNP Assembly";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA"
Lalb_08636	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
Lalb_07352	13	Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
Lalb_07827	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
Lalb_08896	4	KEGG: 00230+6.3.5.2;MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2;Reactome: R-HSA-73817	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis"
Lalb_11512	3	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion"
Lalb_10951	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
Lalb_13940	16	Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-176412;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-983168	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_07584	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
Lalb_10826	8	Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-176187	"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress"
Lalb_01183	2	MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70	"Pseudouridine degradation";"Pyrimidine metabolism"
Lalb_01278	5	Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
Lalb_14508	5	Reactome: R-HSA-2426168;Reactome: R-HSA-75105;Reactome: R-HSA-9029558;Reactome: R-HSA-163765;Reactome: R-HSA-199220	"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism"
Lalb_04428	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
Lalb_12463	16	Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72695	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex"
Lalb_04558	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
Lalb_04723	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
Lalb_08357	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
Lalb_06686	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
Lalb_03855	13	Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72764	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination"
Lalb_02572	7	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination"
Lalb_09859	6	Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5693616	"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange"
Lalb_08280	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
Lalb_10852	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
Lalb_12850	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
Lalb_05227	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_12056	1	MetaCyc: PWY-7511	"Protein ubiquitination"
Lalb_02424	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_13728	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
Lalb_01445	6	Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-2022090	"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Assembly of collagen fibrils and other multimeric structures"
Lalb_07867	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
Lalb_04189	10	MetaCyc: PWY-5484;Reactome: R-HSA-70263;KEGG: 00562+5.3.1.1;KEGG: 00010+5.3.1.1;MetaCyc: PWY-1042;KEGG: 00051+5.3.1.1;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-6142;KEGG: 00710+5.3.1.1	"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Inositol phosphate metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism";"Glycolysis";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms"
Lalb_00023	1	Reactome: R-HSA-156588	"Glucuronidation"
Lalb_03345	14	Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-203927;Reactome: R-HSA-426486;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723	"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation"
Lalb_03036	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
Lalb_07746	13	Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane"
Lalb_08107	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
Lalb_11986	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
Lalb_07921	7	Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-8950505;Reactome: R-HSA-5620922	"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"BBSome-mediated cargo-targeting to cilium"
Lalb_00525	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
Lalb_03573	13	Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-1799339	"Viral mRNA Translation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane"
Lalb_04548	3	MetaCyc: PWY-4361;Reactome: R-HSA-1237112;KEGG: 00270+1.13.11.54	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"Cysteine and methionine metabolism"
Lalb_11270	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
Lalb_02987	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
Lalb_13491	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
Lalb_13493	42	Reactome: R-HSA-201722;Reactome: R-HSA-427413;Reactome: R-HSA-5617472;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-977225;Reactome: R-HSA-8936459;Reactome: R-HSA-5334118;Reactome: R-HSA-110329;Reactome: R-HSA-3214841;Reactome: R-HSA-73772;Reactome: R-HSA-110328;Reactome: R-HSA-606279;Reactome: R-HSA-3214842;Reactome: R-HSA-9610379;Reactome: R-HSA-3214858;Reactome: R-HSA-212300;Reactome: R-HSA-5250924;Reactome: R-HSA-110330;Reactome: R-HSA-2299718;Reactome: R-HSA-2559580;Reactome: R-HSA-2559586;Reactome: R-HSA-110331;Reactome: R-HSA-9018519;Reactome: R-HSA-5693571;Reactome: R-HSA-3214815;Reactome: R-HSA-8939236;Reactome: R-HSA-1221632;Reactome: R-HSA-3214847;Reactome: R-HSA-9616222;Reactome: R-HSA-912446;Reactome: R-HSA-427359;Reactome: R-HSA-171306;Reactome: R-HSA-5625886;Reactome: R-HSA-5693565;Reactome: R-HSA-2559582;Reactome: R-HSA-73728;Reactome: R-HSA-5578749;Reactome: R-HSA-427389;Reactome: R-HSA-1912408;Reactome: R-HSA-5693607;Reactome: R-HSA-69473	"Formation of the beta-catenin:TCF transactivating complex";"NoRC negatively regulates rRNA expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Amyloid fiber formation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"DNA methylation";"Cleavage of the damaged pyrimidine";"PKMTs methylate histone lysines";"RNA Polymerase I Promoter Escape";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Deposition of new CENPA-containing nucleosomes at the centromere";"HDMs demethylate histones";"HCMV Late Events";"RMTs methylate histone arginines";"PRC2 methylates histones and DNA";"B-WICH complex positively regulates rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected purine";"Condensation of Prophase Chromosomes";"Oxidative Stress Induced Senescence";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged purine";"Estrogen-dependent gene expression";"Nonhomologous End-Joining (NHEJ)";"HDACs deacetylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Meiotic synapsis";"HATs acetylate histones";"Transcriptional regulation of granulopoiesis";"Meiotic recombination";"SIRT1 negatively regulates rRNA expression";"Packaging Of Telomere Ends";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Senescence-Associated Secretory Phenotype (SASP)";"RNA Polymerase I Promoter Opening";"Transcriptional regulation by small RNAs";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Pre-NOTCH Transcription and Translation";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint"
Lalb_03163	56	Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-8854050	"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"Regulation of RAS by GAPs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"
Lalb_11651	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)"
Lalb_14071	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
Lalb_03020	12	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9619483;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-5628897;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Relaxin signaling pathway";"Activation of AMPK downstream of NMDARs";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Metabolic Genes";"Human cytomegalovirus infection";"Macroautophagy";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
Lalb_01312	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_01685	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
Lalb_11180	57	Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-6798695;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978	"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"Regulation of RAS by GAPs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"Neutrophil degranulation";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Interleukin-1 signaling";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)"
Lalb_08662	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
Lalb_05909	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
Lalb_01632	16	MetaCyc: PWY-7218;MetaCyc: PWY-5484;KEGG: 00010+4.2.1.11;MetaCyc: PWY-6886;MetaCyc: PWY-5723;Reactome: R-HSA-70263;KEGG: 00680+4.2.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-7124;MetaCyc: PWY-1042;MetaCyc: PWY-6901;MetaCyc: PWY-7003;MetaCyc: PWY-1622;MetaCyc: PWY-6142;MetaCyc: PWY-8004;MetaCyc: PWY-2221	"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Rubisco shunt";"Gluconeogenesis";"Methane metabolism";"Glycolysis";"Ethylene biosynthesis V (engineered)";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"Formaldehyde assimilation I (serine pathway)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway I";"Entner-Doudoroff pathway III (semi-phosphorylative)"
Lalb_11511	1	Reactome: R-HSA-6785807	"Interleukin-4 and Interleukin-13 signaling"
Lalb_09262	1	Reactome: R-HSA-611105	"Respiratory electron transport"
Lalb_01073	12	Reactome: R-HSA-9013507;Reactome: R-HSA-1251985;Reactome: R-HSA-2644606;Reactome: R-HSA-9017802;Reactome: R-HSA-193692;Reactome: R-HSA-3928665;Reactome: R-HSA-977225;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-205043;Reactome: R-HSA-2979096	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Noncanonical activation of NOTCH3";"Regulated proteolysis of p75NTR";"EPH-ephrin mediated repulsion of cells";"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
Lalb_08592	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_02652	11	MetaCyc: PWY-3881;MetaCyc: PWY-6992;Reactome: R-HSA-446205;MetaCyc: PWY-7456;MetaCyc: PWY-7586;KEGG: 00520+5.3.1.8;MetaCyc: PWY-882;MetaCyc: PWY-3861;Reactome: R-HSA-4043916;MetaCyc: PWY-5659;KEGG: 00051+5.3.1.8	"Mannitol biosynthesis";"1,5-anhydrofructose degradation";"Synthesis of GDP-mannose";"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Amino sugar and nucleotide sugar metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Mannitol degradation II";"Defective MPI causes MPI-CDG (CDG-1b)";"GDP-mannose biosynthesis";"Fructose and mannose metabolism"
Lalb_07860	4	Reactome: R-HSA-6804115;Reactome: R-HSA-983189;Reactome: R-HSA-429947;Reactome: R-HSA-6811434	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Kinesins";"Deadenylation of mRNA";"COPI-dependent Golgi-to-ER retrograde traffic"
Lalb_07942	5	Reactome: R-HSA-196108;Reactome: R-HSA-5579026;Reactome: R-HSA-1362409;Reactome: R-HSA-211976;Reactome: R-HSA-2395516	"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin"
Lalb_09195	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
Lalb_01317	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
Lalb_00571	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
Lalb_00764	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
Lalb_04725	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
Lalb_01523	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
Lalb_10045	16	Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72764	"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination"
Lalb_00035	13	Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-2408557	"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Selenocysteine synthesis"
Lalb_11469	1	Reactome: R-HSA-6798163	"Choline catabolism"
Lalb_07732	7	MetaCyc: PWY-7791;KEGG: 00250+2.1.3.2;KEGG: 00240+3.5.2.3;MetaCyc: PWY-5686;Reactome: R-HSA-500753;MetaCyc: PWY-7790;KEGG: 00240+2.1.3.2	"UMP biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"UMP biosynthesis I";"Pyrimidine biosynthesis";"UMP biosynthesis II";"Pyrimidine metabolism"
Lalb_04530	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
Lalb_00964	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
Lalb_13787	1	Reactome: R-HSA-191859	"snRNP Assembly"
Lalb_03213	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
Lalb_02268	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
Lalb_10246	3	Reactome: R-HSA-162658;Reactome: R-HSA-204005;Reactome: R-HSA-6807878	"Golgi Cisternae Pericentriolar Stack Reorganization";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport"
Lalb_07276	6	Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16	"Circadian Clock";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
Lalb_13647	4	Reactome: R-HSA-379716;Reactome: R-HSA-2408557;MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"Cytosolic tRNA aminoacylation";"Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
Lalb_01356	13	Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Viral mRNA Translation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
Lalb_14086	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
Lalb_10186	6	Reactome: R-HSA-6798695;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241	"Neutrophil degranulation";"Tryptophan metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import"
Lalb_07133	1	Reactome: R-HSA-156588	"Glucuronidation"
Lalb_14170	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
Lalb_09441	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
Lalb_03038	7	KEGG: 00020+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-5362517;KEGG: 00620+1.2.4.1;Reactome: R-HSA-204174;Reactome: R-HSA-70268;Reactome: R-HSA-389661	"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation"
Lalb_03570	13	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation"
Lalb_10189	1	Reactome: R-HSA-189200	"Cellular hexose transport"
Lalb_03043	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
Lalb_06099	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-6433	"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)"
Lalb_12461	2	KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240	"Tryptophan metabolism";"Tryptophan catabolism"
Lalb_01276	7	Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942	"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition"
Lalb_06096	14	MetaCyc: PWY-5972;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7036	"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II"
Lalb_11640	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
Lalb_13033	6	Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827	"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression"
Lalb_06168	11	Reactome: R-HSA-400253;Reactome: R-HSA-6790901;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-6791226	"Circadian Clock";"rRNA modification in the nucleus and cytosol";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_03586	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
Lalb_05205	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
Lalb_03018	1	MetaCyc: PWY-7511	"Protein ubiquitination"
Lalb_14150	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_10715	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
Lalb_04059	13	Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-186797;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-2214320;Reactome: R-HSA-1474244;Reactome: R-HSA-3000171;Reactome: R-HSA-419037;Reactome: R-HSA-2243919;Reactome: R-HSA-216083;Reactome: R-HSA-3000178;Reactome: R-HSA-3000157	"Collagen chain trimerization";"Collagen degradation";"Signaling by PDGF";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Anchoring fibril formation";"Extracellular matrix organization";"Non-integrin membrane-ECM interactions";"NCAM1 interactions";"Crosslinking of collagen fibrils";"Integrin cell surface interactions";"ECM proteoglycans";"Laminin interactions"
Lalb_03803	7	Reactome: R-HSA-5617472;Reactome: R-HSA-212300;Reactome: R-HSA-8953750;Reactome: R-HSA-9609690;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-3214841	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PRC2 methylates histones and DNA";"Transcriptional Regulation by E2F6";"HCMV Early Events";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"PKMTs methylate histone lysines"
Lalb_11226	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_13950	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
Lalb_00683	15	Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-176412;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-8853884;Reactome: R-HSA-176408	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"Transcriptional Regulation by VENTX";"Regulation of APC/C activators between G1/S and early anaphase"
Lalb_12672	13	Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
Lalb_10733	13	Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Viral mRNA Translation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit"
Lalb_12375	1	MetaCyc: PWY-7511	"Protein ubiquitination"
Lalb_12734	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
Lalb_04910	6	MetaCyc: PWY-7820;MetaCyc: PWY-7346;KEGG: 00040+1.1.1.22;KEGG: 00520+1.1.1.22;Reactome: R-HSA-173599;KEGG: 00053+1.1.1.22	"Teichuronic acid biosynthesis (B. subtilis 168)";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate";"Ascorbate and aldarate metabolism"
Lalb_01800	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
Lalb_03973	4	Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
Lalb_11980	18	MetaCyc: PWY-7117;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00400+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00401+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00710+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00960+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-6638	"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Phenylalanine metabolism";"(R)-cysteate degradation";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Novobiocin biosynthesis";"Coenzyme M biosynthesis II";"Carbon fixation in photosynthetic organisms";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Isoquinoline alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Alanine, aspartate and glutamate metabolism";"Tyrosine metabolism";"Arginine biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Sulfolactate degradation III"
Lalb_10639	2	Reactome: R-HSA-416476;Reactome: R-HSA-389397	"G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors"
Lalb_04260	2	Reactome: R-HSA-194840;Reactome: R-HSA-8876198	"Rho GTPase cycle";"RAB GEFs exchange GTP for GDP on RABs"
Lalb_12903	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
Lalb_11123	7	Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
Lalb_03480	3	Reactome: R-HSA-2299718;Reactome: R-HSA-3214841;Reactome: R-HSA-6804760	"Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines";"Regulation of TP53 Activity through Methylation"
Lalb_13837	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
Lalb_13858	56	Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-8941858;Reactome: R-HSA-5610785;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-174113;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751	"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"Regulation of RUNX3 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Interleukin-1 signaling";"Hedgehog 'on' state";"SCF-beta-TrCP mediated degradation of Emi1";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RAS by GAPs";"Degradation of AXIN";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Regulation of PTEN stability and activity"
Lalb_01989	13	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation"
Lalb_02541	2	Reactome: R-HSA-9627069;Reactome: R-HSA-111458	"Regulation of the apoptosome activity";"Formation of apoptosome"
Lalb_03798	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
Lalb_01711	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
Lalb_00054	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
Lalb_00935	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
Lalb_06706	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_06135	3	Reactome: R-HSA-6785807;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8854691	"Interleukin-4 and Interleukin-13 signaling";"T cell receptor signaling pathway";"Interleukin-20 family signaling"
Lalb_03888	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
Lalb_03333	2	Reactome: R-HSA-196807;KEGG: 00760+6.3.1.5	"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism"
Lalb_03234	12	Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813	"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Separation of Sister Chromatids"
Lalb_04884	1	Reactome: R-HSA-1483101	"Synthesis of PS"
Lalb_13119	5	Reactome: R-HSA-532668;Reactome: R-HSA-381426;Reactome: R-HSA-901042;Reactome: R-HSA-8957275;Reactome: R-HSA-879415	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Calnexin/calreticulin cycle";"Post-translational protein phosphorylation";"Advanced glycosylation endproduct receptor signaling"
Lalb_04024	3	KEGG: 00130+4.1.1.90;MetaCyc: PWY-7999;Reactome: R-HSA-159740	"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors"
Lalb_11007	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
Lalb_00167	27	Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-168333	"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"snRNP Assembly";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery"
Lalb_11589	5	KEGG: 00020+4.1.1.32;Reactome: R-HSA-70263;KEGG: 00010+4.1.1.32;MetaCyc: PWY-7383;KEGG: 00620+4.1.1.32	"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism"
Lalb_09041	5	Reactome: R-HSA-446210;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013	"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III"
Lalb_12085	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
Lalb_13374	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
Lalb_09064	2	KEGG: 00513+2.4.1.142;KEGG: 00510+2.4.1.142	"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis"
Lalb_04544	6	Reactome: R-HSA-1855183;MetaCyc: PWY-6362;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363	"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation"
Lalb_05236	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
Lalb_03438	8	Reactome: R-HSA-1632852;Reactome: R-HSA-5674400;Reactome: R-HSA-5628897;Reactome: R-HSA-112308;Reactome: R-HSA-8854214;Reactome: R-HSA-380972;Reactome: R-HSA-165181;Reactome: R-HSA-198323	"Macroautophagy";"Constitutive Signaling by AKT1 E17K in Cancer";"TP53 Regulates Metabolic Genes";"Presynaptic depolarization and calcium channel opening";"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Inhibition of TSC complex formation by PKB";"AKT phosphorylates targets in the cytosol"
Lalb_10688	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
Lalb_05872	1	Reactome: R-HSA-977443	"GABA receptor activation"
Lalb_08389	11	Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-5696397;Reactome: R-HSA-68952;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-110314	"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"DNA replication initiation";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex"
Lalb_07369	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
Lalb_10241	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_06583	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
Lalb_06660	6	Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
Lalb_09036	3	Reactome: R-HSA-202427;Reactome: R-HSA-6798695;Reactome: R-HSA-6807004	"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation";"Negative regulation of MET activity"
Lalb_02330	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
Lalb_04373	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
Lalb_04251	3	Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-110312	"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Translesion synthesis by REV1"
Lalb_03037	40	Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-77075;Reactome: R-HSA-5601884;Reactome: R-HSA-167290;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-8851708;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-167160;Reactome: R-HSA-203927;Reactome: R-HSA-5578749;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-168325;Reactome: R-HSA-5617472;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-6803529;Reactome: R-HSA-6781823;Reactome: R-HSA-72203;Reactome: R-HSA-6782210;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-76042;Reactome: R-HSA-72163	"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"Estrogen-dependent gene expression";"RNA Pol II CTD phosphorylation and interaction with CE";"PIWI-interacting RNA (piRNA) biogenesis";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Signaling by FGFR2 IIIa TM";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"MicroRNA (miRNA) biogenesis";"Transcriptional regulation by small RNAs";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Viral Messenger RNA Synthesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Dual incision in TC-NER";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"FGFR2 alternative splicing";"Formation of TC-NER Pre-Incision Complex";"Processing of Capped Intron-Containing Pre-mRNA";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Splicing - Major Pathway"
Lalb_03414	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
Lalb_05207	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
Lalb_04709	13	Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-192823	"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Viral mRNA Translation"
Lalb_05074	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
Lalb_00906	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
Lalb_02070	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
Lalb_06028	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
Lalb_09318	7	MetaCyc: PWY-5659;MetaCyc: PWY-7456;MetaCyc: PWY-7586;Reactome: R-HSA-446205;KEGG: 00051+5.4.2.8;MetaCyc: PWY-882;KEGG: 00520+5.4.2.8	"GDP-mannose biosynthesis";"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Synthesis of GDP-mannose";"Fructose and mannose metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism"
Lalb_08364	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
Lalb_07195	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_00587	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
Lalb_14569	3	KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980	"Photosynthesis";"Oxidative phosphorylation";"ATP biosynthesis"
Lalb_12474	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
Lalb_07095	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
Lalb_07497	5	Reactome: R-HSA-1482883;Reactome: R-HSA-6798695;KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20;Reactome: R-HSA-75109	"Acyl chain remodeling of DAG and TAG";"Neutrophil degranulation";"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism";"Triglyceride biosynthesis"
Lalb_11307	12	Reactome: R-HSA-174362;Reactome: R-HSA-2408550;MetaCyc: PWY-5340;MetaCyc: PWY-6683;KEGG: 00920+2.7.7.4;KEGG: 00230+2.7.1.25;KEGG: 00920+2.7.1.25;MetaCyc: PWY-6932;KEGG: 00261+2.7.7.4;KEGG: 00230+2.7.7.4;KEGG: 00450+2.7.7.4;MetaCyc: PWY-5278	"Transport and synthesis of PAPS";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfate activation for sulfonation";"Assimilatory sulfate reduction III";"Sulfur metabolism";"Purine metabolism";"Sulfur metabolism";"Selenate reduction";"Monobactam biosynthesis";"Purine metabolism";"Selenocompound metabolism";"Sulfite oxidation III"
Lalb_03738	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
Lalb_03737	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
Lalb_03728	9	MetaCyc: PWY-6983;MetaCyc: PWY-5663;MetaCyc: PWY-5664;MetaCyc: PWY-6703;Reactome: R-HSA-1474151;MetaCyc: PWY-7852;KEGG: 00790+3.5.4.16;MetaCyc: PWY-7442;MetaCyc: PWY-6147	"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"Preq0 biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Folate biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I"
Lalb_02288	1	Reactome: R-HSA-5685939	"HDR through MMEJ (alt-NHEJ)"
Lalb_04169	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
Lalb_07506	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
Lalb_05640	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
Lalb_05371	6	MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis"
Lalb_02284	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
Lalb_00278	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
Lalb_12932	2	Reactome: R-HSA-390471;Reactome: R-HSA-429958	"Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease"
Lalb_00427	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825	"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis"
Lalb_05475	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
Lalb_09664	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
Lalb_12547	4	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription"
Lalb_04127	5	Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-983170	"COPII-mediated vesicle transport";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
Lalb_06987	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_04174	5	MetaCyc: PWY-3341;MetaCyc: PWY-6344;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981	"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)"
Lalb_10206	11	MetaCyc: PWY-6352;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660514;Reactome: R-HSA-1632852;Reactome: R-HSA-1660516;Reactome: R-HSA-1660517;KEGG: 00562+2.7.1.137;Reactome: R-HSA-168138;Reactome: R-HSA-109704;Reactome: R-HSA-1660499;Reactome: R-HSA-5668599	"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the Golgi membrane";"Macroautophagy";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane";"Inositol phosphate metabolism";"Toll Like Receptor 9 (TLR9) Cascade";"PI3K Cascade";"Synthesis of PIPs at the plasma membrane";"RHO GTPases Activate NADPH Oxidases"
Lalb_02942	24	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-5626467	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Recycling pathway of L1";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs"
Lalb_12985	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
Lalb_06974	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
Lalb_12445	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
Lalb_13391	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
Lalb_02333	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_01114	1	Reactome: R-HSA-2024096	"HS-GAG degradation"
Lalb_07870	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
Lalb_06258	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_10376	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
Lalb_12278	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
Lalb_13947	6	KEGG: 00030+5.1.3.1;MetaCyc: PWY-5723;KEGG: 00710+5.1.3.1;MetaCyc: PWY-1861;KEGG: 00040+5.1.3.1;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Rubisco shunt";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose and glucuronate interconversions";"Pentose phosphate pathway"
Lalb_03486	5	MetaCyc: PWY-7185;Reactome: R-HSA-499943;MetaCyc: PWY-7176;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7177	"UTP and CTP dephosphorylation I";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"Pyrimidine metabolism";"UTP and CTP dephosphorylation II"
Lalb_13943	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
Lalb_02594	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
Lalb_06296	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
Lalb_12111	5	Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-72163	"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway"
Lalb_04184	4	KEGG: 00513+2.4.1.131;Reactome: R-HSA-4551295;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.131	"Various types of N-glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
Lalb_06535	5	Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811434;Reactome: R-HSA-6811440	"COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network"
Lalb_05426	8	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Signaling by Hippo";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
Lalb_12173	13	Reactome: R-HSA-532668;Reactome: R-HSA-9646399;Reactome: R-HSA-5689896;Reactome: R-HSA-3371511;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-110320;Reactome: R-HSA-5358346;Reactome: R-HSA-8866654;Reactome: R-HSA-5689877;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-8876725	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Aggrephagy";"Ovarian tumor domain proteases";"HSF1 activation";"Neutrophil degranulation";"ABC-family proteins mediated transport";"Translesion Synthesis by POLH";"Hedgehog ligand biogenesis";"E3 ubiquitin ligases ubiquitinate target proteins";"Josephin domain DUBs";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Protein methylation"
Lalb_00870	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
Lalb_10276	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
Lalb_09965	1	Reactome: R-HSA-189200	"Cellular hexose transport"
Lalb_06179	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
Lalb_12640	3	Reactome: R-HSA-8939243;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence"
Lalb_04370	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
Lalb_03176	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
Lalb_08883	2	Reactome: R-HSA-5619061;Reactome: R-HSA-425397	"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules"
Lalb_11368	6	Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-429958	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease"
Lalb_09462	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_13198	6	MetaCyc: PWY-7234;Reactome: R-HSA-73817;MetaCyc: PWY-6124;KEGG: 00670+2.1.2.3;MetaCyc: PWY-6123;KEGG: 00230+3.5.4.10+2.1.2.3	"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism"
Lalb_11465	1	Reactome: R-HSA-6798163	"Choline catabolism"
Lalb_00482	14	Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167238	"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation"
Lalb_02891	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
Lalb_08084	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
Lalb_14732	1	Reactome: R-HSA-114608	"Platelet degranulation"
Lalb_05190	56	Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-1236974;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER-Phagosome pathway";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity"
Lalb_03857	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
Lalb_13089	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
Lalb_11104	8	Reactome: R-HSA-6782135;Reactome: R-HSA-5689880;Reactome: R-HSA-6781823;Reactome: R-HSA-8866652;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6804757;Reactome: R-HSA-8948747	"Dual incision in TC-NER";"Ub-specific processing proteases";"Formation of TC-NER Pre-Incision Complex";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of TP53 Degradation";"Regulation of PTEN localization"
Lalb_01219	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_04331	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
Lalb_14269	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_06986	1	Reactome: R-HSA-6798163	"Choline catabolism"
Lalb_11369	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
Lalb_03814	5	KEGG: 00270+6.3.2.3;KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403;MetaCyc: PWY-8043;Reactome: R-HSA-5579006	"Cysteine and methionine metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)"
Lalb_11393	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
Lalb_04477	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
Lalb_14151	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_08298	33	Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9610379;Reactome: R-HSA-141444;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-168276;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-2467813;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-159230	"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"HCMV Late Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Separation of Sister Chromatids";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA"
Lalb_00453	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_01783	2	Reactome: R-HSA-6791226;Reactome: R-HSA-390471	"Major pathway of rRNA processing in the nucleolus and cytosol";"Association of TriC/CCT with target proteins during biosynthesis"
Lalb_10891	4	MetaCyc: PWY-8072;MetaCyc: PWY-7383;MetaCyc: PWY-8040;KEGG: 00473+5.1.1.1	"Alanine racemization";"Anaerobic energy metabolism (invertebrates, cytosol)";"Ansatrienin biosynthesis";"D-Alanine metabolism"
Lalb_03487	10	Reactome: R-HSA-167162;Reactome: R-HSA-9018519;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-6807505	"RNA Polymerase II HIV Promoter Escape";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes"
Lalb_04417	3	Reactome: R-HSA-204005;Reactome: R-HSA-162658;Reactome: R-HSA-6807878	"COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPI-mediated anterograde transport"
Lalb_04385	6	Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-6791226	"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_10880	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
Lalb_10063	9	KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902	"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)"
Lalb_03478	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
Lalb_01417	5	Reactome: R-HSA-75896;Reactome: R-HSA-9033500;Reactome: R-HSA-9033241;KEGG: 00565+2.5.1.26;MetaCyc: PWY-7782	"Plasmalogen biosynthesis";"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import";"Ether lipid metabolism";"Plasmalogen biosynthesis"
Lalb_05463	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
Lalb_13904	5	MetaCyc: PWY-5981;KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5667;MetaCyc: PWY-7817	"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)"
Lalb_02603	16	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-156827	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression"
Lalb_12414	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
Lalb_02442	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76071	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
Lalb_00682	3	Reactome: R-HSA-111367;Reactome: R-HSA-73856;Reactome: R-HSA-77588	"SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
Lalb_02270	2	Reactome: R-HSA-975956;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
Lalb_10913	5	Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300;Reactome: R-HSA-5334118;Reactome: R-HSA-427413	"SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA";"DNA methylation";"NoRC negatively regulates rRNA expression"
Lalb_14002	5	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange"
Lalb_14324	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
Lalb_08347	9	Reactome: R-HSA-445355;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;Reactome: R-HSA-6802952;Reactome: R-HSA-114608;Reactome: R-HSA-6798695;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946	"Smooth Muscle Contraction";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions";"Platelet degranulation";"Neutrophil degranulation";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants"
Lalb_01803	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
Lalb_09346	56	Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-5607761;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783	"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Regulation of RAS by GAPs";"Degradation of AXIN";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Hedgehog 'on' state";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome"
Lalb_10600	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
Lalb_00709	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
Lalb_01955	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
Lalb_01729	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
Lalb_13746	26	Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-389960;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-437239;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-5663220	"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Cilium Assembly";"Formation of tubulin folding intermediates by CCT/TriC";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"Kinesins";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Recycling pathway of L1";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"RHO GTPases Activate Formins"
Lalb_14716	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
Lalb_02212	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
Lalb_13454	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
Lalb_10441	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
Lalb_05937	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
Lalb_11078	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
Lalb_00535	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
Lalb_00289	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
Lalb_04446	10	MetaCyc: PWY-7328;MetaCyc: PWY-3821;MetaCyc: PWY-6317;MetaCyc: PWY-7344;Reactome: R-HSA-5609977;MetaCyc: PWY-6527;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6397;KEGG: 00052+5.1.3.2;Reactome: R-HSA-70370	"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"UDP-alpha-D-galactose biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose metabolism";"Galactose catabolism"
Lalb_01891	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
Lalb_09791	3	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation"
Lalb_10849	5	Reactome: R-HSA-8854214;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-165181	"TBC/RABGAPs";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Inhibition of TSC complex formation by PKB"
Lalb_05132	2	KEGG: 00970+6.1.1.7;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
Lalb_05545	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
Lalb_13894	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
Lalb_10906	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_00777	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
Lalb_06400	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
Lalb_07264	7	KEGG: 00620+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;Reactome: R-HSA-389661;Reactome: R-HSA-70268;KEGG: 00020+1.2.4.1;KEGG: 00010+1.2.4.1	"Pyruvate metabolism";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis"
Lalb_04714	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
Lalb_08363	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
Lalb_14030	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
Lalb_02682	5	Reactome: R-HSA-5218921;Reactome: R-HSA-5658442;Reactome: R-HSA-8849471;Reactome: R-HSA-186763;Reactome: R-HSA-3928662	"VEGFR2 mediated cell proliferation";"Regulation of RAS by GAPs";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Downstream signal transduction";"EPHB-mediated forward signaling"
Lalb_12177	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
Lalb_11223	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
Lalb_12234	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
Lalb_12996	10	Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-9018519	"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Estrogen-dependent gene expression"
Lalb_03201	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
Lalb_03716	1	Reactome: R-HSA-1632852	"Macroautophagy"
Lalb_05696	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_08023	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
Lalb_10267	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
Lalb_02957	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
Lalb_04549	13	MetaCyc: PWY-7184;MetaCyc: PWY-7226;MetaCyc: PWY-6545;MetaCyc: PWY-7227;MetaCyc: PWY-7220;MetaCyc: PWY-7210;MetaCyc: PWY-7222;KEGG: 00230+1.17.4.1;KEGG: 00983+1.17.4.1;Reactome: R-HSA-499943;KEGG: 00480+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7198	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Glutathione metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
Lalb_08300	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
Lalb_05271	1	Reactome: R-HSA-1296061	"HCN channels"
Lalb_00228	1	Reactome: R-HSA-191859	"snRNP Assembly"
Lalb_05711	11	Reactome: R-HSA-432040;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-163615	"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Purine metabolism";"G alpha (s) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"PKA activation"
Lalb_07468	6	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids"
Lalb_06599	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
Lalb_09468	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
Lalb_13117	11	MetaCyc: PWY-7254;MetaCyc: PWY-6549;KEGG: 00020+1.1.1.42;Reactome: R-HSA-71403;MetaCyc: PWY-5913;MetaCyc: PWY-6969;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7124;KEGG: 00720+1.1.1.42;MetaCyc: PWY-6728;MetaCyc: PWY-7268	"TCA cycle VII (acetate-producers)";"L-glutamine biosynthesis III";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glutathione metabolism";"Ethylene biosynthesis V (engineered)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
Lalb_07784	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
Lalb_11451	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
Lalb_13742	3	Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-381038	"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"XBP1(S) activates chaperone genes"
Lalb_04873	30	Reactome: R-HSA-69656;Reactome: R-HSA-8948751;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9614399;Reactome: R-HSA-69202;Reactome: R-HSA-199418;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9634638;Reactome: R-HSA-392451;KEGG: 04150+2.7.11.1;Reactome: R-HSA-8876198;Reactome: R-HSA-389357;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-389513;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;KEGG: 04714+2.7.11.1;Reactome: R-HSA-111447;Reactome: R-HSA-8941332;Reactome: R-HSA-6804759;Reactome: R-HSA-6804757;Reactome: R-HSA-5628897;Reactome: R-HSA-1358803;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804758;Reactome: R-HSA-198693;Reactome: R-HSA-211163	"Cyclin A:Cdk2-associated events at S phase entry";"Regulation of PTEN stability and activity";"Relaxin signaling pathway";"Regulation of localization of FOXO transcription factors";"Cyclin E associated events during G1/S transition";"Negative regulation of the PI3K/AKT network";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"G beta:gamma signalling through PI3Kgamma";"mTOR signaling pathway";"RAB GEFs exchange GTP for GDP on RABs";"CD28 dependent PI3K/Akt signaling";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"CTLA4 inhibitory signaling";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"Thermogenesis";"Activation of BAD and translocation to mitochondria";"RUNX2 regulates genes involved in cell migration";"Regulation of TP53 Activity through Association with Co-factors";"Regulation of TP53 Degradation";"TP53 Regulates Metabolic Genes";"Downregulation of ERBB2:ERBB3 signaling";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Acetylation";"AKT phosphorylates targets in the nucleus";"AKT-mediated inactivation of FOXO1A"
Lalb_07612	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_11715	7	Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
Lalb_03294	7	KEGG: 00240+2.4.2.10;MetaCyc: PWY-7791;MetaCyc: PWY-7790;MetaCyc: PWY-5686;Reactome: R-HSA-500753;KEGG: 00983+2.4.2.10;KEGG: 00240+4.1.1.23	"Pyrimidine metabolism";"UMP biosynthesis III";"UMP biosynthesis II";"UMP biosynthesis I";"Pyrimidine biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine metabolism"
Lalb_04958	5	Reactome: R-HSA-111469;Reactome: R-HSA-111464;Reactome: R-HSA-111463;Reactome: R-HSA-111457;Reactome: R-HSA-9627069	"SMAC, XIAP-regulated apoptotic response";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC (DIABLO) binds to IAPs";"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity"
Lalb_06254	3	Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-430039	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease"
Lalb_05907	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
Lalb_11505	5	Reactome: R-HSA-201722;Reactome: R-HSA-5617472;Reactome: R-HSA-3769402;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"Formation of the beta-catenin:TCF transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
Lalb_04253	23	Reactome: R-HSA-416476;Reactome: R-HSA-392451;Reactome: R-HSA-416482;Reactome: R-HSA-6814122;Reactome: R-HSA-392170;Reactome: R-HSA-8964315;Reactome: R-HSA-420092;Reactome: R-HSA-418597;Reactome: R-HSA-428930;Reactome: R-HSA-9009391;Reactome: R-HSA-8964616;Reactome: R-HSA-202040;Reactome: R-HSA-500657;Reactome: R-HSA-418594;Reactome: R-HSA-456926;Reactome: R-HSA-392851;Reactome: R-HSA-432040;Reactome: R-HSA-381676;Reactome: R-HSA-418592;Reactome: R-HSA-418217;Reactome: R-HSA-4086398;Reactome: R-HSA-418555;Reactome: R-HSA-400042	"G alpha (q) signalling events";"G beta:gamma signalling through PI3Kgamma";"G alpha (12/13) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through BTK";"Glucagon-type ligand receptors";"G alpha (z) signalling events";"Thromboxane signalling through TP receptor";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through CDC42";"G-protein activation";"Presynaptic function of Kainate receptors";"G alpha (i) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Prostacyclin signalling through prostacyclin receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PLC beta";"Ca2+ pathway";"G alpha (s) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion"
Lalb_13796	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
Lalb_12792	12	Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-6804756;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Regulation of TP53 Activity through Phosphorylation";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
Lalb_11910	6	MetaCyc: PWY-7442;KEGG: 00790+4.2.3.12;MetaCyc: PWY-6983;MetaCyc: PWY-5663;Reactome: R-HSA-1474151;MetaCyc: PWY-5664	"Drosopterin and aurodrosopterin biosynthesis";"Folate biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis II"
Lalb_04943	5	Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation"
Lalb_03026	5	MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109	"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis"
Lalb_13053	3	Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-8963901	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"Chylomicron remodeling"
Lalb_10943	3	Reactome: R-HSA-3899300;Reactome: R-HSA-6804757;Reactome: R-HSA-9609690	"SUMOylation of transcription cofactors";"Regulation of TP53 Degradation";"HCMV Early Events"
Lalb_08663	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
Lalb_10235	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
Lalb_13224	2	Reactome: R-HSA-2514853;Reactome: R-HSA-2299718	"Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes"
Lalb_03248	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
Lalb_10151	1	Reactome: R-HSA-6798163	"Choline catabolism"
Lalb_01964	9	Reactome: R-HSA-113501;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-174411	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"G1/S-Specific Transcription";"Polymerase switching";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere"
Lalb_05399	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
Lalb_02578	2	Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
Lalb_02384	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
Lalb_04047	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878	"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport"
Lalb_12409	5	KEGG: 00510+1.3.1.94;Reactome: R-HSA-446199;Reactome: R-HSA-4755579;MetaCyc: PWY-6129;Reactome: R-HSA-193048	"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Dolichol and dolichyl phosphate biosynthesis";"Androgen biosynthesis"
Lalb_09099	56	Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050	"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Degradation of AXIN";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"
Lalb_06764	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
Lalb_04179	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
Lalb_00416	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
Lalb_06833	3	Reactome: R-HSA-933542;Reactome: R-HSA-445989;Reactome: R-HSA-1810476	"TRAF6 mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"RIP-mediated NFkB activation via ZBP1"
Lalb_12423	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
Lalb_07591	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
Lalb_13849	18	KEGG: 00620+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-5913;MetaCyc: PWY-6969;KEGG: 00270+1.1.1.37;KEGG: 00680+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-7115;Reactome: R-HSA-70263;KEGG: 00020+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00710+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-561;MetaCyc: PWY-1622;MetaCyc: PWY-8086	"Pyruvate metabolism";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Cysteine and methionine metabolism";"Methane metabolism";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation in photosynthetic organisms";"Glyoxylate and dicarboxylate metabolism";"Reductive TCA cycle II";"Superpathway of glyoxylate cycle and fatty acid degradation";"Formaldehyde assimilation I (serine pathway)";"(S)-lactate fermentation to propanoate, acetate and hydrogen"
Lalb_05866	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
Lalb_01220	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76071	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
Lalb_11722	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
Lalb_02351	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
Lalb_07354	3	Reactome: R-HSA-3108214;Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
Lalb_00889	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
Lalb_00917	3	Reactome: R-HSA-913709;Reactome: R-HSA-480985;KEGG: 00510+2.4.1.117	"O-linked glycosylation of mucins";"Synthesis of dolichyl-phosphate-glucose";"N-Glycan biosynthesis"
Lalb_04160	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
Lalb_13004	52	Reactome: R-HSA-203927;Reactome: R-HSA-5578749;Reactome: R-HSA-167160;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-112382;Reactome: R-HSA-8851708;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-73863;Reactome: R-HSA-167290;Reactome: R-HSA-5601884;Reactome: R-HSA-77075;Reactome: R-HSA-9018519;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-674695;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-72163;Reactome: R-HSA-76071;Reactome: R-HSA-167243;Reactome: R-HSA-76042;Reactome: R-HSA-167287;Reactome: R-HSA-6807505;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-72203;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6803529;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-73772;Reactome: R-HSA-6782135;Reactome: R-HSA-1834949;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-73980;Reactome: R-HSA-5617472;Reactome: R-HSA-427413;Reactome: R-HSA-168325;Reactome: R-HSA-167162;Reactome: R-HSA-76061;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-76066	"MicroRNA (miRNA) biogenesis";"Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"Formation of RNA Pol II elongation complex";"Signaling by FGFR2 IIIa TM";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Termination";"Pausing and recovery of HIV elongation";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"Estrogen-dependent gene expression";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"FGFR2 alternative splicing";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase I Promoter Escape";"Dual incision in TC-NER";"Cytosolic sensors of pathogen-associated DNA";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase III Transcription Termination";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NoRC negatively regulates rRNA expression";"Viral Messenger RNA Synthesis";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
Lalb_10599	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
Lalb_08922	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
Lalb_09500	3	Reactome: R-HSA-392517;Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Rap1 signalling";"Ca2+ pathway";"cGMP effects"
Lalb_03640	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
Lalb_05029	2	Reactome: R-HSA-1632852;Reactome: R-HSA-6798695	"Macroautophagy";"Neutrophil degranulation"
Lalb_02203	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
Lalb_02679	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
Lalb_04170	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
Lalb_06932	8	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-418889	"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Caspase activation via Dependence Receptors in the absence of ligand"
Lalb_01471	4	Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827	"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
Lalb_01035	3	MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1	"Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis"
Lalb_00435	3	Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"HATs acetylate histones";"UCH proteinases";"DNA Damage Recognition in GG-NER"
Lalb_04181	3	KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403;MetaCyc: PWY-7942	"Glutathione metabolism";"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism"
Lalb_12714	4	Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
Lalb_00111	57	Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-211733;Reactome: R-HSA-6798695;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-349425	"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Downstream TCR signaling";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neutrophil degranulation";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1"
Lalb_02907	10	MetaCyc: PWY-7199;MetaCyc: PWY-3841;MetaCyc: PWY-7184;MetaCyc: PWY-7198;KEGG: 00240+2.1.1.45;MetaCyc: PWY-7187;Reactome: R-HSA-499943;Reactome: R-HSA-69205;KEGG: 00670+2.1.1.45;MetaCyc: PWY-7210	"Pyrimidine deoxyribonucleosides salvage";"Folate transformations II (plants)";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"G1/S-Specific Transcription";"One carbon pool by folate";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
Lalb_11467	1	Reactome: R-HSA-6798163	"Choline catabolism"
Lalb_01628	16	Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-176412	"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Phosphorylation of the APC/C"
Lalb_04275	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
Lalb_07254	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
Lalb_03413	15	KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7721;MetaCyc: PWY-7659;MetaCyc: PWY-7102;Reactome: R-HSA-6799198;MetaCyc: PWY-7141;MetaCyc: PWY-6383;MetaCyc: PWY-5123;MetaCyc: PWY-5122;MetaCyc: PWY-7709;MetaCyc: PWY-6859;MetaCyc: PWY-7410;MetaCyc: PWY-7182;MetaCyc: PWY-7736;Reactome: R-HSA-611105	"Terpenoid backbone biosynthesis";"Methyl phomopsenoate biosynthesis";"Viridicatumtoxin biosynthesis";"Bisabolene biosynthesis (engineered)";"Complex I biogenesis";"(3S)-linalool biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Geranyl diphosphate biosynthesis";"(3R)-linalool biosynthesis";"All-trans-farnesol biosynthesis";"Ipsdienol biosynthesis";"Linalool biosynthesis I";"Stellatic acid biosynthesis";"Respiratory electron transport"
Lalb_13959	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
Lalb_01336	4	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
Lalb_06752	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
Lalb_06707	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_00330	4	Reactome: R-HSA-6798163;MetaCyc: PWY-3722;MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1	"Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV";"Glycine, serine and threonine metabolism"
Lalb_02898	8	Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-68952	"Polymerase switching";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation"
Lalb_10327	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_08024	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
Lalb_01851	4	Reactome: R-HSA-3000170;Reactome: R-HSA-2129379;Reactome: R-HSA-3000178;Reactome: R-HSA-216083	"Syndecan interactions";"Molecules associated with elastic fibres";"ECM proteoglycans";"Integrin cell surface interactions"
Lalb_04391	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
Lalb_05674	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
Lalb_05667	4	KEGG: 00280+1.2.1.27;MetaCyc: PWY-5642;Reactome: R-HSA-70895;KEGG: 00640+1.2.1.27	"Valine, leucine and isoleucine degradation";"2,4-dinitrotoluene degradation";"Branched-chain amino acid catabolism";"Propanoate metabolism"
Lalb_02719	4	Reactome: R-HSA-901032;KEGG: 00513+3.2.1.113;KEGG: 00510+3.2.1.113;MetaCyc: PWY-7919	"ER Quality Control Compartment (ERQC)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (plants and animals)"
Lalb_05734	3	MetaCyc: PWY-6689;MetaCyc: PWY-7803;Reactome: R-HSA-6784531	"Trna splicing I";"Trna splicing II";"tRNA processing in the nucleus"
Lalb_08514	6	Reactome: R-HSA-191273;Reactome: R-HSA-446199;KEGG: 00900+4.1.1.33;MetaCyc: PWY-7391;MetaCyc: PWY-922;Reactome: R-HSA-2426168	"Cholesterol biosynthesis";"Synthesis of Dolichyl-phosphate";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)"
Lalb_11973	6	KEGG: 00260+5.4.2.11;MetaCyc: PWY-8004;KEGG: 00680+5.4.2.11;KEGG: 00010+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-5484	"Glycine, serine and threonine metabolism";"Entner-Doudoroff pathway I";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)";"Glycolysis II (from fructose 6-phosphate)"
Lalb_05737	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
Lalb_09567	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
Lalb_02154	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
Lalb_03922	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
Lalb_10342	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
Lalb_04508	3	Reactome: R-HSA-189451;MetaCyc: PWY-7856;KEGG: 00860+2.5.1.141	"Heme biosynthesis";"Heme a biosynthesis";"Porphyrin and chlorophyll metabolism"
Lalb_02118	24	Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-5626467;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736	"Recycling pathway of L1";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"RHO GTPases activate IQGAPs";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors"
Lalb_03669	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
Lalb_01703	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
Lalb_05353	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_02596	2	Reactome: R-HSA-1660499;Reactome: R-HSA-1632852	"Synthesis of PIPs at the plasma membrane";"Macroautophagy"
Lalb_01489	5	Reactome: R-HSA-2022928;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"Heparan sulfate biosynthesis (late stages)"
Lalb_03304	10	Reactome: R-HSA-432720;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-9636383;Reactome: R-HSA-9635644;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-5689880;Reactome: R-HSA-917729	"Lysosome Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Prevention of phagosomal-lysosomal fusion";"Inhibition of membrane repair";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Negative regulation of MET activity";"Ub-specific processing proteases";"Endosomal Sorting Complex Required For Transport (ESCRT)"
Lalb_14177	1	Reactome: R-HSA-5689603	"UCH proteinases"
Lalb_00960	2	Reactome: R-HSA-5578999;Reactome: R-HSA-174403	"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling"
Lalb_06389	6	Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex"
Lalb_09211	44	Reactome: R-HSA-202670;Reactome: R-HSA-8943724;Reactome: R-HSA-162658;Reactome: R-HSA-74749;Reactome: R-HSA-450341;Reactome: R-HSA-6802955;Reactome: R-HSA-2029482;Reactome: R-HSA-5675221;Reactome: R-HSA-879415;Reactome: R-HSA-2559580;Reactome: R-HSA-982772;Reactome: R-HSA-3371453;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559585;Reactome: R-HSA-9634638;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-2871796;Reactome: R-HSA-6802952;Reactome: R-HSA-5674499;Reactome: R-HSA-5674135;Reactome: R-HSA-1295596;Reactome: R-HSA-170968;Reactome: R-HSA-6802948;Reactome: R-HSA-8939211;Reactome: R-HSA-445144;Reactome: R-HSA-444257;Reactome: R-HSA-456926;Reactome: R-HSA-112409;Reactome: R-HSA-9649948;Reactome: R-HSA-2559582;Reactome: R-HSA-9635465;Reactome: R-HSA-5654727;Reactome: R-HSA-9627069;Reactome: R-HSA-5663213;Reactome: R-HSA-6811558;Reactome: R-HSA-198753;Reactome: R-HSA-6802946;Reactome: R-HSA-8940973;Reactome: R-HSA-5654726;Reactome: R-HSA-5654732;Reactome: R-HSA-5654733;Reactome: R-HSA-881907;Reactome: R-HSA-5668599	"ERKs are inactivated";"Regulation of PTEN gene transcription";"Golgi Cisternae Pericentriolar Stack Reorganization";"Signal attenuation";"Activation of the AP-1 family of transcription factors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Regulation of actin dynamics for phagocytic cup formation";"Negative regulation of MAPK pathway";"Advanced glycosylation endproduct receptor signaling";"Oxidative Stress Induced Senescence";"Growth hormone receptor signaling";"Regulation of HSF1-mediated heat shock response";"mTOR signaling pathway";"Oncogene Induced Senescence";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"FCERI mediated MAPK activation";"Signaling by BRAF and RAF fusions";"Negative feedback regulation of MAPK pathway";"MAP2K and MAPK activation";"Spry regulation of FGF signaling";"Frs2-mediated activation";"Signaling by high-kinase activity BRAF mutants";"ESR-mediated signaling";"Signal transduction by L1";"RSK activation";"Thrombin signalling through proteinase activated receptors (PARs)";"RAF-independent MAPK1/3 activation";"Signaling downstream of RAS mutants";"Senescence-Associated Secretory Phenotype (SASP)";"Suppression of apoptosis";"Negative regulation of FGFR2 signaling";"Regulation of the apoptosome activity";"RHO GTPases Activate WASPs and WAVEs";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERK/MAPK targets";"Signaling by moderate kinase activity BRAF mutants";"RUNX2 regulates osteoblast differentiation";"Negative regulation of FGFR1 signaling";"Negative regulation of FGFR3 signaling";"Negative regulation of FGFR4 signaling";"Gastrin-CREB signalling pathway via PKC and MAPK";"RHO GTPases Activate NADPH Oxidases"
Lalb_02632	9	KEGG: 00564+1.1.1.94;MetaCyc: PWY-7902;MetaCyc: PWY-5981;MetaCyc: PWY-7385;MetaCyc: PWY-6118;KEGG: 00564+1.1.1.8;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-7411	"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis III";"1,3-propanediol biosynthesis (engineered)";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)"
Lalb_04248	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661	"Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis"
Lalb_10245	4	KEGG: 00250+1.4.1.14;KEGG: 00910+1.4.1.14;MetaCyc: PWY-6963;Reactome: R-HSA-73621	"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Ammonia assimilation cycle I";"Pyrimidine catabolism"
Lalb_09546	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
Lalb_09846	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
Lalb_03522	3	Reactome: R-HSA-6807505;Reactome: R-HSA-749476;Reactome: R-HSA-76071	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
Lalb_05041	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
Lalb_09024	8	MetaCyc: PWY-5723;Reactome: R-HSA-163754;Reactome: R-HSA-71336;Reactome: R-HSA-6791462;MetaCyc: PWY-1861;KEGG: 00030+2.2.1.2;Reactome: R-HSA-6791055;Reactome: R-HSA-8950505	"Rubisco shunt";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Pentose phosphate pathway";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
Lalb_05765	22	Reactome: R-HSA-6811558;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-432142;Reactome: R-HSA-5675221;Reactome: R-HSA-141444;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-195253;Reactome: R-HSA-5358752;Reactome: R-HSA-389513;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-5339716;Reactome: R-HSA-5467337;Reactome: R-HSA-5663220;Reactome: R-HSA-5358747;Reactome: R-HSA-68877;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-5358751;Reactome: R-HSA-2467813	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Platelet sensitization by LDL";"Negative regulation of MAPK pathway";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"APC truncation mutants have impaired AXIN binding";"RHO GTPases Activate Formins";"S33 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"S45 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids"
Lalb_07395	6	KEGG: 00330+2.6.1.13;Reactome: R-HSA-8964539;MetaCyc: PWY-6922;MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6344	"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)"
Lalb_00820	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
Lalb_13268	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
Lalb_03583	4	Reactome: R-HSA-428540;Reactome: R-HSA-186763;Reactome: R-HSA-4420097;Reactome: R-HSA-373753	"Activation of RAC1";"Downstream signal transduction";"VEGFA-VEGFR2 Pathway";"Nephrin family interactions"
Lalb_03999	13	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-6791226	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_02506	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
Lalb_09186	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
Lalb_02053	5	Reactome: R-HSA-6783310;Reactome: R-HSA-5685938;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400	"Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER"
Lalb_08058	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
Lalb_00472	2	Reactome: R-HSA-446193;Reactome: R-HSA-5633231	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)"
Lalb_00819	10	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5689880;Reactome: R-HSA-3214847;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-201722	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Ub-specific processing proteases";"HATs acetylate histones";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Formation of the beta-catenin:TCF transactivating complex"
Lalb_14040	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
Lalb_10734	4	Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-68884	"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Telophase/Cytokinesis"
Lalb_05372	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
Lalb_06461	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
Lalb_13754	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
Lalb_09669	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
Lalb_11885	8	Reactome: R-HSA-113501;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-174411	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Polymerase switching";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere"
Lalb_10202	4	Reactome: R-HSA-446199;Reactome: R-HSA-4755583;KEGG: 00510+2.7.1.108;MetaCyc: PWY-6129	"Synthesis of Dolichyl-phosphate";"Defective DOLK causes DOLK-CDG (CDG-1m)";"N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis"
Lalb_04058	13	Reactome: R-HSA-419037;Reactome: R-HSA-2243919;Reactome: R-HSA-216083;Reactome: R-HSA-3000178;Reactome: R-HSA-3000157;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-186797;Reactome: R-HSA-1442490;Reactome: R-HSA-2214320;Reactome: R-HSA-2022090;Reactome: R-HSA-3000171;Reactome: R-HSA-1474244	"NCAM1 interactions";"Crosslinking of collagen fibrils";"Integrin cell surface interactions";"ECM proteoglycans";"Laminin interactions";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Signaling by PDGF";"Collagen degradation";"Anchoring fibril formation";"Assembly of collagen fibrils and other multimeric structures";"Non-integrin membrane-ECM interactions";"Extracellular matrix organization"
Lalb_04807	182	Reactome: R-HSA-4641263;Reactome: R-HSA-445989;Reactome: R-HSA-5607761;Reactome: R-HSA-937072;Reactome: R-HSA-2894862;Reactome: R-HSA-936440;Reactome: R-HSA-8866654;Reactome: R-HSA-937039;Reactome: R-HSA-156827;Reactome: R-HSA-8849469;Reactome: R-HSA-912631;Reactome: R-HSA-5685942;Reactome: R-HSA-69601;Reactome: R-HSA-205043;Reactome: R-HSA-68949;Reactome: R-HSA-2979096;Reactome: R-HSA-5654727;Reactome: R-HSA-192823;Reactome: R-HSA-69231;Reactome: R-HSA-9637628;Reactome: R-HSA-201681;Reactome: R-HSA-2559582;Reactome: R-HSA-5668541;Reactome: R-HSA-6804756;Reactome: R-HSA-9014325;Reactome: R-HSA-195253;Reactome: R-HSA-9013973;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-2559585;Reactome: R-HSA-2122947;Reactome: R-HSA-1295596;Reactome: R-HSA-937041;Reactome: R-HSA-4641258;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-5205685;Reactome: R-HSA-1236974;Reactome: R-HSA-5357956;Reactome: R-HSA-5607764;Reactome: R-HSA-72689;Reactome: R-HSA-4608870;Reactome: R-HSA-162588;Reactome: R-HSA-8948747;Reactome: R-HSA-5675482;Reactome: R-HSA-975163;Reactome: R-HSA-450302;Reactome: R-HSA-2565942;Reactome: R-HSA-901032;Reactome: R-HSA-8875360;Reactome: R-HSA-6804757;Reactome: R-HSA-8854050;Reactome: R-HSA-5656121;Reactome: R-HSA-174084;Reactome: R-HSA-3134975;Reactome: R-HSA-110314;Reactome: R-HSA-9613829;Reactome: R-HSA-8856828;Reactome: R-HSA-174490;Reactome: R-HSA-977225;Reactome: R-HSA-5658442;Reactome: R-HSA-174184;Reactome: R-HSA-450321;Reactome: R-HSA-5689877;Reactome: R-HSA-450408;Reactome: R-HSA-1169408;Reactome: R-HSA-9645460;Reactome: R-HSA-1236382;Reactome: R-HSA-8939902;Reactome: R-HSA-975956;Reactome: R-HSA-400253;Reactome: R-HSA-175474;Reactome: R-HSA-3785653;Reactome: R-HSA-72764;Reactome: R-HSA-5675221;Reactome: R-HSA-72702;Reactome: R-HSA-69481;Reactome: R-HSA-975144;Reactome: R-HSA-2173788;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-168638;Reactome: R-HSA-9013507;Reactome: R-HSA-5654732;Reactome: R-HSA-5357905;Reactome: R-HSA-5689896;Reactome: R-HSA-8876493;Reactome: R-HSA-5610783;Reactome: R-HSA-5684264;Reactome: R-HSA-5654726;Reactome: R-HSA-180534;Reactome: R-HSA-8866652;Reactome: R-HSA-174048;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-110312;Reactome: R-HSA-72649;Reactome: R-HSA-9033241;Reactome: R-HSA-179409;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-5696395;Reactome: R-HSA-2173796;Reactome: R-HSA-4641257;Reactome: R-HSA-5678895;Reactome: R-HSA-1253288;Reactome: R-HSA-8863795;Reactome: R-HSA-2122948;Reactome: R-HSA-917937;Reactome: R-HSA-2644606;Reactome: R-HSA-8948751;Reactome: R-HSA-937042;Reactome: R-HSA-174178;Reactome: R-HSA-2672351;Reactome: R-HSA-2173795;Reactome: R-HSA-6782210;Reactome: R-HSA-5362768;Reactome: R-HSA-5696397;Reactome: R-HSA-1358803;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-9636383;Reactome: R-HSA-182971;Reactome: R-HSA-6781827;Reactome: R-HSA-936964;Reactome: R-HSA-72695;Reactome: R-HSA-168928;Reactome: R-HSA-8856825;Reactome: R-HSA-5654733;Reactome: R-HSA-5696400;Reactome: R-HSA-3322077;Reactome: R-HSA-168927;Reactome: R-HSA-6804760;Reactome: R-HSA-975110;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-917729;Reactome: R-HSA-2467813;Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-5693565;Reactome: R-HSA-2173791;Reactome: R-HSA-72706;Reactome: R-HSA-174113;Reactome: R-HSA-2691232;Reactome: R-HSA-5693607;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-532668;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-6783310;Reactome: R-HSA-9633012;Reactome: R-HSA-5656169;Reactome: R-HSA-5689901;Reactome: R-HSA-2408557;Reactome: R-HSA-6782135;Reactome: R-HSA-6791226;Reactome: R-HSA-187577;Reactome: R-HSA-209543;Reactome: R-HSA-156902;Reactome: R-HSA-9646399;Reactome: R-HSA-9615710;Reactome: R-HSA-6807004;Reactome: R-HSA-3769402;Reactome: R-HSA-69541;Reactome: R-HSA-9010553;Reactome: R-HSA-68827;Reactome: R-HSA-69017;Reactome: R-HSA-5358346;Reactome: R-HSA-1799339;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-2559580;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-975957;Reactome: R-HSA-1234176;Reactome: R-HSA-209560	"Regulation of FZD by ubiquitination";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Dectin-1 mediated noncanonical NF-kB signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Negative regulators of DDX58/IFIH1 signaling";"E3 ubiquitin ligases ubiquitinate target proteins";"IRAK1 recruits IKK complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Regulation of signaling by CBL";"HDR through Homologous Recombination (HRR)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"NRIF signals cell death from the nucleus";"Orc1 removal from chromatin";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Negative regulation of FGFR2 signaling";"Viral mRNA Translation";"Cyclin D associated events in G1";"Modulation by Mtb of host immune system";"TCF dependent signaling in response to WNT";"Senescence-Associated Secretory Phenotype (SASP)";"TNFR2 non-canonical NF-kB pathway";"Regulation of TP53 Activity through Phosphorylation";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Degradation of beta-catenin by the destruction complex";"TICAM1-dependent activation of IRF3/IRF7";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Oncogene Induced Senescence";"NOTCH1 Intracellular Domain Regulates Transcription";"Spry regulation of FGF signaling";"IKK complex recruitment mediated by RIP1";"Degradation of DVL";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Pink/Parkin Mediated Mitophagy";"ER-Phagosome pathway";"TNFR1-induced NFkappaB signaling pathway";"CLEC7A (Dectin-1) signaling";"Formation of a pool of free 40S subunits";"Asymmetric localization of PCP proteins";"Budding and maturation of HIV virion";"Regulation of PTEN localization";"Regulation of necroptotic cell death";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"activated TAK1 mediates p38 MAPK activation";"Regulation of PLK1 Activity at G2/M Transition";"ER Quality Control Compartment (ERQC)";"InlB-mediated entry of Listeria monocytogenes into host cell";"Regulation of TP53 Degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Translesion synthesis by POLI";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of innate immune responses to cytosolic DNA";"Recognition of DNA damage by PCNA-containing replication complex";"Chaperone Mediated Autophagy";"Clathrin-mediated endocytosis";"Membrane binding and targetting of GAG proteins";"Amyloid fiber formation";"Regulation of RAS by GAPs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Josephin domain DUBs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ISG15 antiviral mechanism";"Alpha-protein kinase 1 signaling pathway";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Regulation of RUNX2 expression and activity";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Circadian Clock";"Assembly Of The HIV Virion";"Myoclonic epilepsy of Lafora";"Eukaryotic Translation Termination";"Negative regulation of MAPK pathway";"Ribosomal scanning and start codon recognition";"G2/M Checkpoints";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Downregulation of TGF-beta receptor signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"NOD1/2 Signaling Pathway";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Negative regulation of FGFR3 signaling";"Regulation of TNFR1 signaling";"Ovarian tumor domain proteases";"InlA-mediated entry of Listeria monocytogenes into host cells";"Degradation of GLI2 by the proteasome";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Negative regulation of FGFR1 signaling";"Vpu mediated degradation of CD4";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"Translesion synthesis by REV1";"Translation initiation complex formation";"Peroxisomal protein import";"APC-Cdc20 mediated degradation of Nek2A";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Formation of Incision Complex in GG-NER";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Degradation of AXIN";"Defective CFTR causes cystic fibrosis";"Downregulation of ERBB4 signaling";"Downregulation of ERBB2 signaling";"Activated NOTCH1 Transmits Signal to the Nucleus";"Iron uptake and transport";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of PTEN stability and activity";"IRAK2 mediated activation of TAK1 complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Stimuli-sensing channels";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Downregulation of ERBB2:ERBB3 signaling";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Prevention of phagosomal-lysosomal fusion";"EGFR downregulation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Formation of the ternary complex, and subsequently, the 43S complex";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of FGFR4 signaling";"Dual Incision in GG-NER";"Glycogen synthesis";"TICAM1, RIP1-mediated IKK complex recruitment";"Regulation of TP53 Activity through Methylation";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Separation of Sister Chromatids";"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SCF-beta-TrCP mediated degradation of Emi1";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Processing of DNA double-strand break ends";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Fanconi Anemia Pathway";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Termination of translesion DNA synthesis";"Metalloprotease DUBs";"Selenocysteine synthesis";"Dual incision in TC-NER";"Major pathway of rRNA processing in the nucleolus and cytosol";"SCF(Skp2)-mediated degradation of p27/p21";"p75NTR recruits signalling complexes";"Peptide chain elongation";"Aggrephagy";"Late endosomal microautophagy";"Negative regulation of MET activity";"Deactivation of the beta-catenin transactivating complex";"Stabilization of p53";"Regulation of expression of SLITs and ROBOs";"CDT1 association with the CDC6:ORC:origin complex";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog ligand biogenesis";"SRP-dependent cotranslational protein targeting to membrane";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Oxidative Stress Induced Senescence";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NF-kB is activated and signals survival"
Lalb_14122	14	MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-5981;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-7589;MetaCyc: PWY-7587	"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Oleate biosynthesis III (cyanobacteria)"
Lalb_12729	9	Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-191859;Reactome: R-HSA-1368108;Reactome: R-HSA-400253	"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"RORA activates gene expression";"snRNP Assembly";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock"
Lalb_12959	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
Lalb_06800	14	Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-69091	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"Polymerase switching"
Lalb_07696	4	Reactome: R-HSA-5696394;Reactome: R-HSA-532668;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395	"DNA Damage Recognition in GG-NER";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER"
Lalb_03382	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
Lalb_01636	1	MetaCyc: PWY-7511	"Protein ubiquitination"
Lalb_00064	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_04525	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
Lalb_05700	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
Lalb_13636	3	KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3	"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis"
Lalb_01810	1	Reactome: R-HSA-8951664	"Neddylation"
Lalb_13025	5	Reactome: R-HSA-211945;Reactome: R-HSA-211976;Reactome: R-HSA-211981;Reactome: R-HSA-1989781;Reactome: R-HSA-8937144	"Phase I - Functionalization of compounds";"Endogenous sterols";"Xenobiotics";"PPARA activates gene expression";"Aryl hydrocarbon receptor signalling"
Lalb_10742	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
Lalb_00488	26	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-389977;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Recycling pathway of L1";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Post-chaperonin tubulin folding pathway";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"Cilium Assembly";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation"
Lalb_09378	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
Lalb_14550	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
Lalb_00637	11	Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1	"Adenylate cyclase activating pathway";"PKA activation";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Purine metabolism"
Lalb_06990	1	Reactome: R-HSA-419771	"Opsins"
Lalb_08802	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
Lalb_06671	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
Lalb_08972	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
Lalb_02093	6	Reactome: R-HSA-191273;MetaCyc: PWY-7391;KEGG: 00900+2.7.1.36;MetaCyc: PWY-6174;MetaCyc: PWY-922;Reactome: R-HSA-2426168	"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)"
Lalb_11857	2	Reactome: R-HSA-525793;Reactome: R-HSA-373752	"Myogenesis";"Netrin-1 signaling"
Lalb_14014	1	Reactome: R-HSA-5689603	"UCH proteinases"
Lalb_02032	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
Lalb_06276	1	Reactome: R-HSA-5683826	"Surfactant metabolism"
Lalb_13892	12	MetaCyc: PWY-7230;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5871;MetaCyc: PWY-6708;MetaCyc: PWY-5872;Reactome: R-HSA-2142789;MetaCyc: PWY-7233;MetaCyc: PWY-5856;MetaCyc: PWY-5873;MetaCyc: PWY-5855;MetaCyc: PWY-5870;MetaCyc: PWY-5857	"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)"
Lalb_00893	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
Lalb_06495	1	Reactome: R-HSA-5676934	"Protein repair"
Lalb_09080	1	MetaCyc: PWY-6938	"NADH repair"
Lalb_12002	7	Reactome: R-HSA-5632681;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-373080;Reactome: R-HSA-5362798;Reactome: R-HSA-5635838;Reactome: R-HSA-5658034	"Ligand-receptor interactions";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Class B/2 (Secretin family receptors)";"Release of Hh-Np from the secreting cell";"Activation of SMO";"HHAT G278V abrogates palmitoylation of Hh-Np"
Lalb_01958	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
Lalb_14021	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
Lalb_05320	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
Lalb_11132	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
Lalb_08211	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
Lalb_07857	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
Lalb_14636	1	Reactome: R-HSA-611105	"Respiratory electron transport"
Lalb_07594	3	Reactome: R-HSA-8856828;Reactome: R-HSA-8854214;Reactome: R-HSA-8875656	"Clathrin-mediated endocytosis";"TBC/RABGAPs";"MET receptor recycling"
Lalb_02350	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
Lalb_12585	14	MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-6598	"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis"
Lalb_05549	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
Lalb_06267	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
Lalb_09907	5	Reactome: R-HSA-392154;Reactome: R-HSA-1222556;KEGG: 00330+1.14.13.39;KEGG: 00220+1.14.13.39;MetaCyc: PWY-4983	"Nitric oxide stimulates guanylate cyclase";"ROS and RNS production in phagocytes";"Arginine and proline metabolism";"Arginine biosynthesis";"Nitric oxide biosynthesis II (mammals)"
Lalb_09322	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
Lalb_10484	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
Lalb_11597	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
Lalb_10692	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
Lalb_02758	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
Lalb_01486	16	Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72695	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex"
Lalb_01778	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_04684	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
Lalb_13707	2	Reactome: R-HSA-176187;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
Lalb_06371	2	Reactome: R-HSA-196780;Reactome: R-HSA-3371599	"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency"
Lalb_04155	14	Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
Lalb_07334	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
Lalb_00537	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
Lalb_14124	14	MetaCyc: PWY-6969;MetaCyc: PWY-561;KEGG: 00190+1.3.5.1;MetaCyc: PWY-4302;Reactome: R-HSA-71403;MetaCyc: PWY-7279;MetaCyc: PWY-7254;Reactome: R-HSA-611105;MetaCyc: PWY-3781;KEGG: 00720+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-6728;MetaCyc: PWY-5690;KEGG: 00650+1.3.5.1	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Oxidative phosphorylation";"Aerobic respiration III (alternative oxidase pathway)";"Citric acid cycle (TCA cycle)";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle VII (acetate-producers)";"Respiratory electron transport";"Aerobic respiration I (cytochrome c)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Butanoate metabolism"
Lalb_11404	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
Lalb_08768	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
Lalb_04503	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway"
Lalb_08668	12	MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8053;MetaCyc: PWY-7409;MetaCyc: PWY-6803	"Anandamide biosynthesis I";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing"
Lalb_11176	12	Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-3214847;Reactome: R-HSA-1912408;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-8941856;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-210744;Reactome: R-HSA-2894862	"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"HATs acetylate histones";"Pre-NOTCH Transcription and Translation";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
Lalb_01968	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
Lalb_10071	2	Reactome: R-HSA-1663150;Reactome: R-HSA-1660662	"The activation of arylsulfatases";"Glycosphingolipid metabolism"
Lalb_08966	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
Lalb_08231	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
Lalb_13064	1	Reactome: R-HSA-419771	"Opsins"
Lalb_11575	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
Lalb_12075	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
Lalb_05080	12	MetaCyc: PWY-5108;MetaCyc: PWY-5133;MetaCyc: PWY-7857;KEGG: 00010+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-7118;KEGG: 00640+6.2.1.1;MetaCyc: PWY-5132;MetaCyc: PWY-6672;KEGG: 00630+6.2.1.1;KEGG: 00620+6.2.1.1;KEGG: 00680+6.2.1.1	"L-isoleucine biosynthesis V";"Colupulone and cohumulone biosynthesis";"Adlupulone and adhumulone biosynthesis";"Glycolysis / Gluconeogenesis";"Carbon fixation pathways in prokaryotes";"Chitin degradation to ethanol";"Propanoate metabolism";"Lupulone and humulone biosynthesis";"Cis-genanyl-coa degradation";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Methane metabolism"
Lalb_01079	3	Reactome: R-HSA-203615;Reactome: R-HSA-1474151;KEGG: 00790+1.1.1.153	"eNOS activation";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis"
Lalb_07688	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
Lalb_02996	20	KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5392;KEGG: 00020+2.3.3.8;MetaCyc: PWY-6728;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5537;MetaCyc: PWY-5172;MetaCyc: PWY-5538;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6969;Reactome: R-HSA-1268020;Reactome: R-HSA-6798695;MetaCyc: PWY-5913;KEGG: 00660+6.2.1.5;Reactome: R-HSA-163765;KEGG: 00720+6.2.1.5;MetaCyc: PWY-7384;Reactome: R-HSA-75105;Reactome: R-HSA-71403	"Propanoate metabolism";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"Acetyl-coa biosynthesis III (from citrate)";"Pyruvate fermentation to acetate VI";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Mitochondrial protein import";"Neutrophil degranulation";"Partial TCA cycle (obligate autotrophs)";"C5-Branched dibasic acid metabolism";"ChREBP activates metabolic gene expression";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Fatty acyl-CoA biosynthesis";"Citric acid cycle (TCA cycle)"
Lalb_13095	7	Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-1655829;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-203927	"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"MicroRNA (miRNA) biogenesis"
Lalb_10270	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
Lalb_13375	3	Reactome: R-HSA-3359471;Reactome: R-HSA-196741;KEGG: 00860+2.5.1.17	"Defective MMAB causes methylmalonic aciduria type cblB";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Porphyrin and chlorophyll metabolism"
Lalb_05464	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
Lalb_01383	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
Lalb_12927	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
Lalb_13310	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
Lalb_10344	2	Reactome: R-HSA-5689880;MetaCyc: PWY-7511	"Ub-specific processing proteases";"Protein ubiquitination"
Lalb_05982	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
Lalb_03736	4	MetaCyc: PWY-5189;MetaCyc: PWY-5188;KEGG: 00860+2.5.1.61;Reactome: R-HSA-189451	"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
Lalb_13793	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
Lalb_09113	6	Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390471	"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis"
Lalb_02959	7	Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724	"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Macroautophagy";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription"
Lalb_09194	1	Reactome: R-HSA-8951664	"Neddylation"
Lalb_03130	5	Reactome: R-HSA-72165;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"mRNA Splicing - Minor Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
Lalb_00905	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
Lalb_13303	4	Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-112043	"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"PLC beta mediated events"
Lalb_09248	27	Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379	"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"ISG15 antiviral mechanism";"snRNP Assembly";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"HCMV Late Events"
Lalb_08217	10	MetaCyc: PWY-6366;Reactome: R-HSA-1855167;MetaCyc: PWY-4661;MetaCyc: PWY-6554;KEGG: 04070+2.7.1.159;KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-6362;Reactome: R-HSA-983231;MetaCyc: PWY-6365;Reactome: R-HSA-1855204	"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Factors involved in megakaryocyte development and platelet production";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol"
Lalb_03312	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
Lalb_03231	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_05037	2	Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7	"Purine salvage";"Purine metabolism"
Lalb_05339	2	Reactome: R-HSA-1566948;Reactome: R-HSA-2243919	"Elastic fibre formation";"Crosslinking of collagen fibrils"
Lalb_03065	13	Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-1799339	"Viral mRNA Translation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane"
Lalb_07840	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
Lalb_12283	4	Reactome: R-HSA-8963889;Reactome: R-HSA-381033;Reactome: R-HSA-8874211;Reactome: R-HSA-1655829	"Assembly of active LPL and LIPC lipase complexes";"ATF6 (ATF6-alpha) activates chaperones";"CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
Lalb_08533	4	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
Lalb_01744	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
Lalb_01467	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
Lalb_12037	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
Lalb_08595	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
Lalb_11644	6	Reactome: R-HSA-8874211;Reactome: R-HSA-1655829;Reactome: R-HSA-381426;Reactome: R-HSA-8963889;Reactome: R-HSA-8957275;Reactome: R-HSA-381033	"CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Assembly of active LPL and LIPC lipase complexes";"Post-translational protein phosphorylation";"ATF6 (ATF6-alpha) activates chaperones"
Lalb_09011	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
Lalb_13617	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
Lalb_13050	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
Lalb_06847	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
Lalb_01433	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
Lalb_03161	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
Lalb_02003	4	KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737;Reactome: R-HSA-70688;MetaCyc: PWY-6922	"Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism";"L-Ndelta-acetylornithine biosynthesis"
Lalb_12190	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
Lalb_10196	4	KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163;MetaCyc: PWY-3722;MetaCyc: PWY-7494	"Glycine, serine and threonine metabolism";"Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV"
Lalb_07044	19	Reactome: R-HSA-3000497;Reactome: R-HSA-8957275;Reactome: R-HSA-5686938;Reactome: R-HSA-8964041;Reactome: R-HSA-975634;Reactome: R-HSA-3000471;Reactome: R-HSA-3000480;Reactome: R-HSA-8856828;Reactome: R-HSA-8963888;Reactome: R-HSA-8866423;Reactome: R-HSA-8964026;Reactome: R-HSA-8964046;Reactome: R-HSA-202733;Reactome: R-HSA-432142;Reactome: R-HSA-381426;Reactome: R-HSA-8856825;Reactome: R-HSA-3000484;Reactome: R-HSA-8964038;Reactome: R-HSA-8963901	"Scavenging by Class H Receptors";"Post-translational protein phosphorylation";"Regulation of TLR by endogenous ligand";"LDL remodeling";"Retinoid metabolism and transport";"Scavenging by Class B Receptors";"Scavenging by Class A Receptors";"Clathrin-mediated endocytosis";"Chylomicron assembly";"VLDL assembly";"Chylomicron clearance";"VLDL clearance";"Cell surface interactions at the vascular wall";"Platelet sensitization by LDL";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class F Receptors";"LDL clearance";"Chylomicron remodeling"
Lalb_06623	5	Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-427413	"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression"
Lalb_08681	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
Lalb_12717	8	Reactome: R-HSA-4551638;Reactome: R-HSA-8953750;Reactome: R-HSA-5617472;Reactome: R-HSA-8943724;Reactome: R-HSA-9609690;Reactome: R-HSA-2559580;Reactome: R-HSA-3214841;Reactome: R-HSA-212300	"SUMOylation of chromatin organization proteins";"Transcriptional Regulation by E2F6";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of PTEN gene transcription";"HCMV Early Events";"Oxidative Stress Induced Senescence";"PKMTs methylate histone lysines";"PRC2 methylates histones and DNA"
Lalb_02528	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
Lalb_05975	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
Lalb_02746	6	Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68867	"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA";"Assembly of the pre-replicative complex"
Lalb_00619	5	KEGG: 05235+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-112409	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Negative regulation of MAPK pathway";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"RAF-independent MAPK1/3 activation"
Lalb_01214	6	MetaCyc: PWY-5269;MetaCyc: PWY-7817;Reactome: R-HSA-1483166;MetaCyc: PWY-5668;KEGG: 00564+2.7.8.5;Reactome: R-HSA-1483148	"Cardiolipin biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Synthesis of PA";"Cardiolipin biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PG"
Lalb_02281	1	Reactome: R-HSA-373753	"Nephrin family interactions"
Lalb_06360	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.5	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
Lalb_03629	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
Lalb_13279	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
Lalb_14464	5	Reactome: R-HSA-2426168;Reactome: R-HSA-75105;Reactome: R-HSA-9029558;Reactome: R-HSA-163765;Reactome: R-HSA-199220	"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism"
Lalb_03868	9	MetaCyc: PWY-5744;MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;MetaCyc: PWY-5789;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142	"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
Lalb_04161	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
Lalb_01265	9	Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-426486;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-203927;Reactome: R-HSA-380320;Reactome: R-HSA-380284	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Small interfering RNA (siRNA) biogenesis";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"MicroRNA (miRNA) biogenesis";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
Lalb_13792	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
Lalb_05026	5	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8875360	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell"
Lalb_10173	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
Lalb_10932	8	Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-6798695;Reactome: R-HSA-9627069;Reactome: R-HSA-6803207;Reactome: R-HSA-111464;Reactome: R-HSA-8953750;Reactome: R-HSA-111463	"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"Neutrophil degranulation";"Regulation of the apoptosome activity";"TP53 Regulates Transcription of Caspase Activators and Caspases";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Transcriptional Regulation by E2F6";"SMAC (DIABLO) binds to IAPs"
Lalb_10555	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_12972	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
Lalb_01413	3	MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048	"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG"
Lalb_13880	1	Reactome: R-HSA-1483255	"PI Metabolism"
Lalb_00423	16	Reactome: R-HSA-167590;Reactome: R-HSA-8856828;Reactome: R-HSA-177504;Reactome: R-HSA-5099900;Reactome: R-HSA-8866427;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-8964038;Reactome: R-HSA-164939;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-182218;Reactome: R-HSA-416993	"Nef Mediated CD4 Down-regulation";"Clathrin-mediated endocytosis";"Retrograde neurotrophin signalling";"WNT5A-dependent internalization of FZD4";"VLDLR internalisation and degradation";"Recycling pathway of L1";"MHC class II antigen presentation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"LDL clearance";"Nef mediated downregulation of CD28 cell surface expression";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"Nef Mediated CD8 Down-regulation";"Trafficking of GluR2-containing AMPA receptors"
Lalb_02493	22	MetaCyc: PWY-6598;KEGG: 00062+4.2.1.134;MetaCyc: PWY-6958;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7053;MetaCyc: PWY-7036;MetaCyc: PWY-7606;MetaCyc: PWY-7726;MetaCyc: PWY-5353;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7592;MetaCyc: PWY-7727;MetaCyc: PWY-7728;MetaCyc: PWY-6433;MetaCyc: PWY-7049;MetaCyc: PWY-7725;MetaCyc: PWY-7035	"Sciadonate biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis"
Lalb_02072	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
Lalb_04435	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
Lalb_01273	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
Lalb_05226	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_08200	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
Lalb_12448	4	MetaCyc: PWY-7375;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-72086	"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping"
Lalb_04612	12	MetaCyc: PWY-5132;KEGG: 00630+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00620+6.2.1.1;KEGG: 00680+6.2.1.1;KEGG: 00010+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-7118;KEGG: 00640+6.2.1.1;MetaCyc: PWY-5133;MetaCyc: PWY-7857;MetaCyc: PWY-5108	"Lupulone and humulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Cis-genanyl-coa degradation";"Pyruvate metabolism";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Carbon fixation pathways in prokaryotes";"Chitin degradation to ethanol";"Propanoate metabolism";"Colupulone and cohumulone biosynthesis";"Adlupulone and adhumulone biosynthesis";"L-isoleucine biosynthesis V"
Lalb_13032	7	Reactome: R-HSA-110362;Reactome: R-HSA-5696400;Reactome: R-HSA-5685939;Reactome: R-HSA-2173795;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394	"POLB-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"HDR through MMEJ (alt-NHEJ)";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER"
Lalb_08630	3	Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1	"Aspartate and asparagine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism"
Lalb_10968	3	Reactome: R-HSA-3065678;Reactome: R-HSA-3065676;Reactome: R-HSA-983168	"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"SUMO is conjugated to E1 (UBA2:SAE1)";"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_12974	1	Reactome: R-HSA-186797	"Signaling by PDGF"
Lalb_08982	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
Lalb_05827	6	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
Lalb_00437	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
Lalb_13003	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
Lalb_06455	1	Reactome: R-HSA-419771	"Opsins"
Lalb_11626	10	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates"
Lalb_14108	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
Lalb_11538	6	KEGG: 00230+3.5.4.3;Reactome: R-HSA-74259;MetaCyc: PWY-7442;MetaCyc: PWY-5497;MetaCyc: PWY-6606;MetaCyc: PWY-6608	"Purine metabolism";"Purine catabolism";"Drosopterin and aurodrosopterin biosynthesis";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III"
Lalb_02775	6	MetaCyc: PWY-622;Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.18;Reactome: R-HSA-3878781;MetaCyc: PWY-7900;MetaCyc: PWY-5067	"Starch biosynthesis";"Glycogen synthesis";"Starch and sucrose metabolism";"Glycogen storage disease type IV (GBE1)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)"
Lalb_05820	27	Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-168271	"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"snRNP Assembly";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus"
Lalb_01066	5	Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604	"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling"
Lalb_13307	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
Lalb_03185	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
Lalb_02574	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
Lalb_03364	1	Reactome: R-HSA-8951664	"Neddylation"
Lalb_09594	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
Lalb_00510	6	Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-6791226	"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol"
Lalb_08589	7	MetaCyc: PWY-6123;MetaCyc: PWY-7219;KEGG: 00230+4.3.2.2;MetaCyc: PWY-6124;Reactome: R-HSA-73817;KEGG: 00250+4.3.2.2;MetaCyc: PWY-7234	"Inosine-5'-phosphate biosynthesis I";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis III"
Lalb_08801	7	KEGG: 00230+1.1.1.205;MetaCyc: PWY-5695;MetaCyc: PWY-6596;MetaCyc: PWY-7221;Reactome: R-HSA-6798695;Reactome: R-HSA-73817;KEGG: 00983+1.1.1.205	"Purine metabolism";"Inosine 5'-phosphate degradation";"Adenosine nucleotides degradation I";"Guanosine ribonucleotides de novo biosynthesis";"Neutrophil degranulation";"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes"
Lalb_13641	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
Lalb_04920	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
Lalb_11649	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
Lalb_01482	1	MetaCyc: PWY-7511	"Protein ubiquitination"
Lalb_11420	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
Lalb_09026	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
Lalb_00466	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
Lalb_08135	56	Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323	"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Degradation of AXIN";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling"
Lalb_11960	1	Reactome: R-HSA-8949613	"Cristae formation"
Lalb_09193	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
Lalb_11950	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
Lalb_06564	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
Lalb_11905	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
Lalb_03520	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
Lalb_04970	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
Lalb_11429	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
Lalb_01842	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
Lalb_06914	13	MetaCyc: PWY-7210;MetaCyc: PWY-7222;KEGG: 00230+1.17.4.1;KEGG: 00983+1.17.4.1;Reactome: R-HSA-499943;KEGG: 00480+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7184;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-6545;MetaCyc: PWY-7220	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Glutathione metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II"
Lalb_02020	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
Lalb_06681	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
Lalb_08843	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
Lalb_07031	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_04825	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
Lalb_09597	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
Lalb_01538	1	Reactome: R-HSA-70350	"Fructose catabolism"
Lalb_12675	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
Lalb_06744	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
Lalb_09054	12	Reactome: R-HSA-167290;Reactome: R-HSA-6804756;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955	"Pausing and recovery of HIV elongation";"Regulation of TP53 Activity through Phosphorylation";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation"
Lalb_13654	3	Reactome: R-HSA-111471;Reactome: R-HSA-140837;Reactome: R-HSA-9645722	"Apoptotic factor-mediated response";"Intrinsic Pathway of Fibrin Clot Formation";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function"
Lalb_09059	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
Lalb_02360	3	Reactome: R-HSA-1660662;Reactome: R-HSA-5626978;Reactome: R-HSA-193681	"Glycosphingolipid metabolism";"TNFR1-mediated ceramide production";"Ceramide signalling"
Lalb_04195	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
Lalb_00760	12	Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-73863;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-427413;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-73772;Reactome: R-HSA-76071;Reactome: R-HSA-5250924;Reactome: R-HSA-73762	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation"
Lalb_02282	5	MetaCyc: PWY-7822;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)"
Lalb_10743	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
Lalb_10725	7	MetaCyc: PWY-6610;Reactome: R-HSA-74217;MetaCyc: PWY-7805;MetaCyc: PWY-7807;Reactome: R-HSA-6798695;KEGG: 00230+2.4.2.7;MetaCyc: PWY-6605	"Adenine salvage";"Purine salvage";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Neutrophil degranulation";"Purine metabolism";"Adenine and adenosine salvage II"
Lalb_07082	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_01633	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
Lalb_14060	2	Reactome: R-HSA-2173788;Reactome: R-HSA-5689603	"Downregulation of TGF-beta receptor signaling";"UCH proteinases"
Lalb_09079	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
Lalb_09535	6	MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism"
Lalb_08233	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
Lalb_08678	2	Reactome: R-HSA-375280;Reactome: R-HSA-416476	"Amine ligand-binding receptors";"G alpha (q) signalling events"
Lalb_11486	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
Lalb_02567	22	Reactome: R-HSA-432142;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-6811558;Reactome: R-HSA-196299;Reactome: R-HSA-389513;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-195253;Reactome: R-HSA-5675221;Reactome: R-HSA-5358749;Reactome: R-HSA-141444;Reactome: R-HSA-5358751;Reactome: R-HSA-5673000;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-5358747;Reactome: R-HSA-4641262;Reactome: R-HSA-5467340;Reactome: R-HSA-5339716;Reactome: R-HSA-5467337	"Platelet sensitization by LDL";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Beta-catenin phosphorylation cascade";"CTLA4 inhibitory signaling";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"Negative regulation of MAPK pathway";"S37 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S45 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"S33 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"AXIN missense mutants destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"APC truncation mutants have impaired AXIN binding"
Lalb_04742	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
Lalb_09272	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
Lalb_03068	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
Lalb_09861	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
Lalb_10057	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
Lalb_03295	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
Lalb_06973	2	Reactome: R-HSA-2151201;KEGG: 00970+6.1.1.14	"Transcriptional activation of mitochondrial biogenesis";"Aminoacyl-tRNA biosynthesis"
Lalb_08685	6	Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-176974	"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Unwinding of DNA"
Lalb_01825	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
Lalb_11514	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
Lalb_09065	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
Lalb_09593	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
Lalb_05437	1	Reactome: R-HSA-8963889	"Assembly of active LPL and LIPC lipase complexes"
Lalb_05020	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
Lalb_01067	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
Lalb_13222	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
Lalb_04246	10	KEGG: 00564+2.3.1.15;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-8053;Reactome: R-HSA-1483166	"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Synthesis of PA"
Lalb_02355	8	Reactome: R-HSA-190873;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665;Reactome: R-HSA-5099900;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-432720;Reactome: R-HSA-8856825	"Gap junction degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis"
Lalb_02879	9	Reactome: R-HSA-3560801;Reactome: R-HSA-3560783;Reactome: R-HSA-1971475;Reactome: R-HSA-2022928;Reactome: R-HSA-4420332;Reactome: R-HSA-2024096;Reactome: R-HSA-3656253;Reactome: R-HSA-975634;Reactome: R-HSA-3656237	"Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG biosynthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Retinoid metabolism and transport";"Defective EXT2 causes exostoses 2"
Lalb_01129	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
Lalb_06720	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6798695;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic"
Lalb_09553	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
Lalb_06798	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76071	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
Lalb_11182	17	MetaCyc: PWY-5743;KEGG: 00640+6.4.1.2;MetaCyc: PWY-6722;KEGG: 00720+6.4.1.2;KEGG: 00254+6.4.1.2;Reactome: R-HSA-200425;MetaCyc: PWY-6679;KEGG: 00620+6.4.1.2;Reactome: R-HSA-3371599;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;MetaCyc: PWY-4381;MetaCyc: PWY-5744;MetaCyc: PWY-5789;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5966-1;Reactome: R-HSA-196780	"3-hydroxypropanoate cycle";"Propanoate metabolism";"Candicidin biosynthesis";"Carbon fixation pathways in prokaryotes";"Aflatoxin biosynthesis";"Carnitine metabolism";"Jadomycin biosynthesis";"Pyruvate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Biotin transport and metabolism"
Lalb_10460	3	KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077;MetaCyc: PWY-5067	"Starch and sucrose metabolism";"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)"
Lalb_06704	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_13902	13	MetaCyc: PWY-7112;MetaCyc: PWY-2261;KEGG: 00053+1.8.5.1;Reactome: R-HSA-156590;Reactome: R-HSA-196836;MetaCyc: PWY-7533;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00983+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-4061;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6370	"4-hydroxy-2-nonenal detoxification";"Ascorbate glutathione cycle";"Ascorbate and aldarate metabolism";"Glutathione conjugation";"Vitamin C (ascorbate) metabolism";"Gliotoxin biosynthesis";"Glutathione metabolism";"Drug metabolism - other enzymes";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Drug metabolism - cytochrome P450";"Ascorbate recycling (cytosolic)"
Lalb_10723	1	Reactome: R-HSA-8951664	"Neddylation"
Lalb_07087	3	Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-110329	"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine"
Lalb_08407	3	MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33	"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
Lalb_11296	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
Lalb_06342	5	MetaCyc: PWY-6902;MetaCyc: PWY-6855;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)"
Lalb_02152	3	MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6	"Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism"
Lalb_02865	29	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-349425;Reactome: R-HSA-5693579;Reactome: R-HSA-5693571;Reactome: R-HSA-6803204;KEGG: 04926+2.7.11.1;Reactome: R-HSA-912446;Reactome: R-HSA-6804760;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-69541;Reactome: R-HSA-6804757;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6803207;Reactome: R-HSA-5693565;Reactome: R-HSA-6796648;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2559586;KEGG: 04151+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693548;Reactome: R-HSA-6804756	"Human cytomegalovirus infection";"mTOR signaling pathway";"Regulation of HSF1-mediated heat shock response";"Autodegradation of the E3 ubiquitin ligase COP1";"Homologous DNA Pairing and Strand Exchange";"Nonhomologous End-Joining (NHEJ)";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Relaxin signaling pathway";"Meiotic recombination";"Regulation of TP53 Activity through Methylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Stabilization of p53";"Regulation of TP53 Degradation";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human immunodeficiency virus 1 infection";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"TP53 Regulates Transcription of DNA Repair Genes";"Human papillomavirus infection";"DNA Damage/Telomere Stress Induced Senescence";"PI3K-Akt signaling pathway";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Thermogenesis";"Sensing of DNA Double Strand Breaks";"Regulation of TP53 Activity through Phosphorylation"
Lalb_01165	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
Lalb_09824	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
Lalb_01444	7	Reactome: R-HSA-9018519;Reactome: R-HSA-2470946;Reactome: R-HSA-1221632;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-3108214;Reactome: R-HSA-2467813	"Estrogen-dependent gene expression";"Cohesin Loading onto Chromatin";"Meiotic synapsis";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Separation of Sister Chromatids"
Lalb_03645	5	Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-1655829	"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
Lalb_07495	14	Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-174411	"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"Translesion synthesis by POLI";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Polymerase switching on the C-strand of the telomere"
Lalb_09119	5	Reactome: R-HSA-977225;Reactome: R-HSA-983168;Reactome: R-HSA-5205685;Reactome: R-HSA-5689877;Reactome: R-HSA-9646399	"Amyloid fiber formation";"Antigen processing: Ubiquitination & Proteasome degradation";"Pink/Parkin Mediated Mitophagy";"Josephin domain DUBs";"Aggrephagy"
Lalb_13128	14	MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-975634;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;MetaCyc: PWY-6803	"Anandamide biosynthesis I";"Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Retinoid metabolism and transport";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Phosphatidylcholine acyl editing"
Lalb_08814	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_01210	3	Reactome: R-HSA-6783984;KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine degradation";"Glycine, serine and threonine metabolism";"One carbon pool by folate"
Lalb_04334	6	Reactome: R-HSA-5632968;Reactome: R-HSA-5632927;Reactome: R-HSA-6796648;Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-5358606	"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH3";"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
Lalb_05994	10	MetaCyc: PWY-6362;MetaCyc: PWY-6361;MetaCyc: PWY-6369;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855191;Reactome: R-HSA-1855167;MetaCyc: PWY-6554;MetaCyc: PWY-6372;MetaCyc: PWY-4661;KEGG: 04070+2.7.1.158	"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Inositol diphosphates biosynthesis";"Inositol phosphate metabolism";"Synthesis of IPs in the nucleus";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol signaling system"
Lalb_00489	1	Reactome: R-HSA-8951664	"Neddylation"
Lalb_11106	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
Lalb_02073	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
Lalb_03310	8	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-975957	"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
Lalb_08965	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_11473	1	Reactome: R-HSA-6798163	"Choline catabolism"
Lalb_05281	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
Lalb_08326	3	MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism"
Lalb_13152	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
Lalb_04035	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
Lalb_12683	1	MetaCyc: PWY-7511	"Protein ubiquitination"
Lalb_04338	6	MetaCyc: PWY-6317;KEGG: 00520+2.7.7.12;MetaCyc: PWY-6527;Reactome: R-HSA-70370;Reactome: R-HSA-5609978;KEGG: 00052+2.7.7.12	"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Galactose catabolism";"Defective GALT can cause Galactosemia";"Galactose metabolism"
Lalb_01748	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus"
Lalb_07843	5	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6855;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)"
Lalb_02340	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
Lalb_09642	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
Lalb_13667	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
Lalb_10827	1	Reactome: R-HSA-189200	"Cellular hexose transport"
Lalb_02701	1	Reactome: R-HSA-8951664	"Neddylation"
Lalb_08506	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
Lalb_01990	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
Lalb_02872	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
Lalb_01170	5	KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264;MetaCyc: PWY-5381;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108	"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
Lalb_06668	6	MetaCyc: PWY-7286;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;MetaCyc: PWY-7285;Reactome: R-HSA-6787450;MetaCyc: PWY-6829	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"Methylwyosine biosynthesis";"tRNA modification in the mitochondrion";"Trna methylation (yeast)"
Lalb_07763	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
Lalb_02313	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
Lalb_08605	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
Lalb_10959	27	Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214	"snRNP Assembly";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins"
Lalb_10813	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
Lalb_05406	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
Lalb_09915	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
Lalb_07587	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
Lalb_00447	1	Reactome: R-HSA-8951664	"Neddylation"
Lalb_11641	2	Reactome: R-HSA-1237112;Reactome: R-HSA-8950505	"Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
Lalb_09285	9	MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52	"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Other glycan degradation";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series"
Lalb_03368	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
Lalb_09140	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_02666	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
Lalb_09995	4	Reactome: R-HSA-196741;Reactome: R-HSA-3359462;Reactome: R-HSA-8964011;Reactome: R-HSA-3359463	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective AMN causes hereditary megaloblastic anemia 1";"HDL clearance";"Defective CUBN causes hereditary megaloblastic anemia 1"
Lalb_11159	3	Reactome: R-HSA-1483213;MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65	"Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism"
Lalb_02728	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
Lalb_10330	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
Lalb_03156	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
Lalb_11450	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
Lalb_06346	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
Lalb_01475	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_10112	8	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Activation of RAC1";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
Lalb_02695	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
Lalb_07430	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
Lalb_02364	8	Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-6804115;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes"
Lalb_09073	1	Reactome: R-HSA-6803529	"FGFR2 alternative splicing"
Lalb_06674	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
Lalb_03786	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
Lalb_09370	2	Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
Lalb_09425	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
Lalb_06691	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300	"SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors"
Lalb_11076	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
Lalb_12763	6	MetaCyc: PWY-6722;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-4381;Reactome: R-HSA-196780;MetaCyc: PWY-5789	"Candicidin biosynthesis";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle"
Lalb_10993	16	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-156827	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression"
Lalb_12674	4	Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-418594;Reactome: R-HSA-5689880	"Degradation of AXIN";"TCF dependent signaling in response to WNT";"G alpha (i) signalling events";"Ub-specific processing proteases"
Lalb_08673	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
Lalb_02231	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
Lalb_10440	14	Reactome: R-HSA-1632852;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-5620924;Reactome: R-HSA-9646399	"Macroautophagy";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Intraflagellar transport";"Aggrephagy"
Lalb_12617	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.4;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
Lalb_07355	5	Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73772	"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape"
Lalb_13627	1	Reactome: R-HSA-8935690	"Digestion"
Lalb_03809	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
Lalb_04878	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
Lalb_04162	40	Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-168325;Reactome: R-HSA-5617472;Reactome: R-HSA-167162;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-6782135;Reactome: R-HSA-6803529;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-6781823;Reactome: R-HSA-72203;Reactome: R-HSA-6782210;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-9018519;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-5601884;Reactome: R-HSA-167290;Reactome: R-HSA-73779;Reactome: R-HSA-8851708;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-5578749;Reactome: R-HSA-203927;Reactome: R-HSA-167160	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"Viral Messenger RNA Synthesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II HIV Promoter Escape";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Dual incision in TC-NER";"FGFR2 alternative splicing";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"Formation of TC-NER Pre-Incision Complex";"Processing of Capped Intron-Containing Pre-mRNA";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"Estrogen-dependent gene expression";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"PIWI-interacting RNA (piRNA) biogenesis";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Signaling by FGFR2 IIIa TM";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"Transcriptional regulation by small RNAs";"MicroRNA (miRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
Lalb_07039	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
Lalb_08481	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
Lalb_02085	7	KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-4702;MetaCyc: PWY-2301;Reactome: R-HSA-1855183;KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363	"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Phytate degradation I";"Myo-inositol biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation"
Lalb_00172	4	Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-5579026	"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
Lalb_12549	4	Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
Lalb_09219	10	MetaCyc: PWY-7559;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-8001;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-6842;MetaCyc: PWY-5826	"Glutathione degradation (DUG pathway";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis"
Lalb_11133	12	Reactome: R-HSA-196780;MetaCyc: PWY-6277;MetaCyc: PWY-6121;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.2;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;KEGG: 00230+6.3.3.1;MetaCyc: PWY-6122;KEGG: 00230+6.3.4.13;MetaCyc: PWY-6613;KEGG: 00230+2.1.2.2	"Biotin transport and metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine metabolism"
Lalb_04664	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
Lalb_02266	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
Lalb_03764	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
Lalb_08766	29	Reactome: R-HSA-3371511;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-5696395;Reactome: R-HSA-5656169;Reactome: R-HSA-3371453;Reactome: R-HSA-174437;Reactome: R-HSA-5358606;Reactome: R-HSA-3108214;Reactome: R-HSA-110314;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-69166;Reactome: R-HSA-6804756;Reactome: R-HSA-6783310;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-68962;Reactome: R-HSA-5693616;Reactome: R-HSA-110320;Reactome: R-HSA-5655862;Reactome: R-HSA-5358565;Reactome: R-HSA-5656121;Reactome: R-HSA-110312	"HSF1 activation";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"Formation of Incision Complex in GG-NER";"Termination of translesion DNA synthesis";"Regulation of HSF1-mediated heat shock response";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"SUMOylation of DNA damage response and repair proteins";"Recognition of DNA damage by PCNA-containing replication complex";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Removal of the Flap Intermediate";"Regulation of TP53 Activity through Phosphorylation";"Fanconi Anemia Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Activation of the pre-replicative complex";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion Synthesis by POLH";"Translesion synthesis by POLK";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by POLI";"Translesion synthesis by REV1"
Lalb_11951	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
Lalb_08150	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
Lalb_11813	4	KEGG: 00040+2.7.1.17;Reactome: R-HSA-5661270;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Pentose and glucuronate interconversions";"Formation of xylulose-5-phosphate";"Glycerolipid metabolism";"Glycerol degradation I"
Lalb_03293	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
Lalb_04915	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
Lalb_10564	6	Reactome: R-HSA-72163;MetaCyc: PWY-7511;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135	"mRNA Splicing - Major Pathway";"Protein ubiquitination";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER"
Lalb_10319	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
Lalb_09570	4	Reactome: R-HSA-166058;Reactome: R-HSA-6799198;Reactome: R-HSA-975871;Reactome: R-HSA-975138	"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"Complex I biogenesis";"MyD88 cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation"
Lalb_02626	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
Lalb_05846	4	MetaCyc: PWY-2781;Reactome: R-HSA-6787450;KEGG: 00908+2.5.1.75;Reactome: R-HSA-6782315	"Cis-zeatin biosynthesis";"tRNA modification in the mitochondrion";"Zeatin biosynthesis";"tRNA modification in the nucleus and cytosol"
Lalb_10140	57	Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-6798695;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-382556	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Regulation of RAS by GAPs";"Degradation of AXIN";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Neutrophil degranulation";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport"
Lalb_05000	13	MetaCyc: PWY-6969;MetaCyc: PWY-5392;MetaCyc: PWY-5913;KEGG: 00660+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5538;Reactome: R-HSA-71403;KEGG: 00720+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5537;MetaCyc: PWY-5690	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate VI";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"Methylaspartate cycle";"Pyruvate fermentation to acetate V";"TCA cycle II (plants and fungi)"
Lalb_05044	13	Reactome: R-HSA-5578775;Reactome: R-HSA-4086398;Reactome: R-HSA-112043;Reactome: R-HSA-2029485;Reactome: R-HSA-422356;Reactome: R-HSA-983695;Reactome: R-HSA-139853;Reactome: R-HSA-1489509;Reactome: R-HSA-114508;Reactome: R-HSA-5607763;Reactome: R-HSA-381676;Reactome: R-HSA-5218921;Reactome: R-HSA-2871809	"Ion homeostasis";"Ca2+ pathway";"PLC beta mediated events";"Role of phospholipids in phagocytosis";"Regulation of insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Elevation of cytosolic Ca2+ levels";"DAG and IP3 signaling";"Effects of PIP2 hydrolysis";"CLEC7A (Dectin-1) induces NFAT activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"VEGFR2 mediated cell proliferation";"FCERI mediated Ca+2 mobilization"
Lalb_10641	4	Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5358346	"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis"
Lalb_06335	14	MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-5972	"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)"
Lalb_09197	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
Lalb_01289	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
Lalb_06581	3	Reactome: R-HSA-429947;Reactome: R-HSA-6804115;Reactome: R-HSA-5617472	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
Lalb_00398	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
Lalb_09501	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
Lalb_09108	1	Reactome: R-HSA-1632852	"Macroautophagy"
Lalb_05077	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
Lalb_04786	16	Reactome: R-HSA-1810476;Reactome: R-HSA-5603037;Reactome: R-HSA-5603041;Reactome: R-HSA-166058;Reactome: R-HSA-975155;Reactome: R-HSA-6811558;Reactome: R-HSA-3134963;Reactome: R-HSA-5602498;Reactome: R-HSA-209543;Reactome: R-HSA-975110;Reactome: R-HSA-975871;Reactome: R-HSA-1236974;Reactome: R-HSA-975138;Reactome: R-HSA-9020702;Reactome: R-HSA-1257604;Reactome: R-HSA-5602680	"RIP-mediated NFkB activation via ZBP1";"IRAK4 deficiency (TLR5)";"IRAK4 deficiency (TLR2/4)";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 dependent cascade initiated on endosome";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"MyD88 deficiency (TLR2/4)";"p75NTR recruits signalling complexes";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"MyD88 cascade initiated on plasma membrane";"ER-Phagosome pathway";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"Interleukin-1 signaling";"PIP3 activates AKT signaling";"MyD88 deficiency (TLR5)"
Lalb_11530	14	MetaCyc: PWY-7587;MetaCyc: PWY-7782;MetaCyc: PWY-8051;MetaCyc: PWY-7589;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-8055;MetaCyc: PWY-6453;MetaCyc: PWY-7411	"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Synthesis of PA";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)"
Lalb_01138	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
Lalb_05022	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
Lalb_13723	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
Lalb_03159	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
Lalb_09048	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
Lalb_11267	10	Reactome: R-HSA-6798695;MetaCyc: PWY-5691;KEGG: 00230+3.5.2.17;MetaCyc: PWY-7394;Reactome: R-HSA-975634;Reactome: R-HSA-2453902;Reactome: R-HSA-977225;Reactome: R-HSA-2453864;MetaCyc: PWY-7849;Reactome: R-HSA-3000171	"Neutrophil degranulation";"Urate conversion to allantoin I";"Purine metabolism";"Urate conversion to allantoin II";"Retinoid metabolism and transport";"The canonical retinoid cycle in rods (twilight vision)";"Amyloid fiber formation";"Retinoid cycle disease events";"Urate conversion to allantoin III";"Non-integrin membrane-ECM interactions"
Lalb_10301	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_12176	4	Reactome: R-HSA-390247;KEGG: 00410+4.1.1.9;Reactome: R-HSA-9033241;KEGG: 00640+4.1.1.9	"Beta-oxidation of very long chain fatty acids";"beta-Alanine metabolism";"Peroxisomal protein import";"Propanoate metabolism"
Lalb_03718	11	KEGG: 05165+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-171007;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-450302	"Human papillomavirus infection";"Oxidative Stress Induced Senescence";"p38MAPK events";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"activated TAK1 mediates p38 MAPK activation"
Lalb_11714	5	Reactome: R-HSA-5545619;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-201681;Reactome: R-HSA-5689880	"XAV939 inhibits tankyrase, stabilizing AXIN";"Degradation of AXIN";"Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases"
Lalb_12876	15	Reactome: R-HSA-2559585;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408	"Oncogene Induced Senescence";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation"
Lalb_10807	8	KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;KEGG: 00195+7.1.2.2;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Oxidative phosphorylation";"ATP biosynthesis";"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Photosynthesis";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
Lalb_13094	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
Lalb_04820	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
Lalb_07890	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
Lalb_00665	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
Lalb_04188	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
Lalb_03906	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
Lalb_00833	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
Lalb_06471	19	Reactome: R-HSA-380320;MetaCyc: PWY-7224;KEGG: 00983+2.7.4.6;Reactome: R-HSA-380270;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7221;MetaCyc: PWY-7210;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7187;MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-7205;MetaCyc: PWY-7220	"Recruitment of NuMA to mitotic centrosomes";"Purine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"Recruitment of mitotic centrosome proteins and complexes";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis II"
Lalb_00182	57	Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-8941858;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-6798695;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236	"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"Regulation of RUNX3 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Interleukin-1 signaling";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neutrophil degranulation";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
Lalb_09689	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
Lalb_01537	1	Reactome: R-HSA-8951664	"Neddylation"
Lalb_09622	1	Reactome: R-HSA-525793	"Myogenesis"
Lalb_01352	1	Reactome: R-HSA-191859	"snRNP Assembly"
Lalb_02016	4	Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17;KEGG: 00790+4.1.99.22	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Folate biosynthesis"
Lalb_04499	3	KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3;Reactome: R-HSA-977347	"Methane metabolism";"Glycine, serine and threonine metabolism";"Serine biosynthesis"
Lalb_13056	16	Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72695	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex"
Lalb_10982	2	Reactome: R-HSA-73621;Reactome: R-HSA-500753	"Pyrimidine catabolism";"Pyrimidine biosynthesis"
Lalb_07787	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
Lalb_05732	5	MetaCyc: PWY-3821;MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6	"D-galactose detoxification";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism"
Lalb_09276	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
Lalb_12089	8	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2465910	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"MASTL Facilitates Mitotic Progression"
Lalb_12426	3	MetaCyc: PWY-7546;MetaCyc: PWY-6482;Reactome: R-HSA-5358493	"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2"
Lalb_08867	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
Lalb_04452	2	Reactome: R-HSA-1268020;Reactome: R-HSA-611105	"Mitochondrial protein import";"Respiratory electron transport"
Lalb_09676	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
Lalb_10372	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
Lalb_10269	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"