Accession_ID	Pathway_Count	Pathway_IDs	Pathway_Names
LHES016476-PA	6	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-6798695;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Neutrophil degranulation";"ROS and RNS production in phagocytes"
LHES005822-PA	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
LHES013324-PA	4	Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-400511	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
LHES015614-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
LHES007301-PA	5	MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation"
LHES003987-PA	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
LHES007541-PA	7	Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-166208	"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"mTOR signalling";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling"
LHES012663-PA	1	Reactome: R-HSA-8951664	"Neddylation"
LHES015543-PA	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554	"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
LHES007700-PA	1	Reactome: R-HSA-71288	"Creatine metabolism"
LHES003310-PA	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
LHES010815-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
LHES009213-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
LHES011373-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
LHES004673-PA	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
LHES016368-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
LHES004636-PA	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
LHES001664-PA	26	Reactome: R-HSA-1989781;Reactome: R-HSA-3214847;Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-400253;Reactome: R-HSA-1912408;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-3134973;Reactome: R-HSA-5621575;Reactome: R-HSA-8941856;Reactome: R-HSA-9614657;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-2122947;Reactome: R-HSA-9617629;Reactome: R-HSA-381340;Reactome: R-HSA-1234158;Reactome: R-HSA-9013508;Reactome: R-HSA-5617472;Reactome: R-HSA-3371568;Reactome: R-HSA-8866907;Reactome: R-HSA-9013695;Reactome: R-HSA-918233;Reactome: R-HSA-201722;Reactome: R-HSA-3899300	"PPARA activates gene expression";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Circadian Clock";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"CD209 (DC-SIGN) signaling";"RUNX3 regulates NOTCH signaling";"FOXO-mediated transcription of cell death genes";"RORA activates gene expression";"Estrogen-dependent gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression by Hypoxia-inducible Factor";"NOTCH3 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Attenuation phase";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH4 Intracellular Domain Regulates Transcription";"TRAF3-dependent IRF activation pathway";"Formation of the beta-catenin:TCF transactivating complex";"SUMOylation of transcription cofactors"
LHES000227-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
LHES013582-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
LHES005286-PA	4	Reactome: R-HSA-375276;Reactome: R-HSA-977606;Reactome: R-HSA-174577;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"Regulation of Complement cascade";"Activation of C3 and C5";"G alpha (i) signalling events"
LHES004814-PA	1	Reactome: R-HSA-8951664	"Neddylation"
LHES006350-PA	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
LHES003365-PA	56	Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-69601;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-68827;Reactome: R-HSA-8941858;Reactome: R-HSA-8951664;Reactome: R-HSA-1236978;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-8939236;Reactome: R-HSA-8939902;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-1169091	"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"ABC-family proteins mediated transport";"Degradation of DVL";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX3 expression and activity";"Neddylation";"Cross-presentation of soluble exogenous antigens (endosomes)";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX2 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Activation of NF-kappaB in B cells"
LHES005847-PA	2	Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Cargo concentration in the ER";"COPII-mediated vesicle transport"
LHES011651-PA	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
LHES004289-PA	5	Reactome: R-HSA-8856828;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.36;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.36	"Clathrin-mediated endocytosis";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Inositol phosphate metabolism"
LHES009977-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
LHES012277-PA	1	Reactome: R-HSA-400253	"Circadian Clock"
LHES008650-PA	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
LHES000600-PA	5	Reactome: R-HSA-5218921;Reactome: R-HSA-186763;Reactome: R-HSA-3928662;Reactome: R-HSA-5658442;Reactome: R-HSA-8849471	"VEGFR2 mediated cell proliferation";"Downstream signal transduction";"EPHB-mediated forward signaling";"Regulation of RAS by GAPs";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"
LHES010282-PA	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
LHES010464-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
LHES003284-PA	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
LHES002075-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
LHES010514-PA	7	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
LHES012003-PA	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
LHES014300-PA	13	Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits"
LHES002722-PA	31	MetaCyc: PWY-5994;MetaCyc: PWY-8049;MetaCyc: PWY-7723;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558;MetaCyc: PWY-8047;MetaCyc: PWY-6113;MetaCyc: PWY-7858;MetaCyc: PWY-6799;MetaCyc: PWY-8012;MetaCyc: PWY-7663;MetaCyc: PWY-5366;MetaCyc: PWY-5966-1;MetaCyc: PWY-4381;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5147;MetaCyc: PWY-6519;MetaCyc: PWY-7388;MetaCyc: PWY-5142;Reactome: R-HSA-75105;MetaCyc: PWY-5989;MetaCyc: PWY-5367;MetaCyc: PWY-6282;MetaCyc: PWYG-321;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7746;MetaCyc: PWY-5973;Reactome: R-HSA-199220;Reactome: R-HSA-163765;MetaCyc: PWY-5971;MetaCyc: PWY-7664	"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Pederin biosynthesis";"Bacterial bioluminescence";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Bryostatin biosynthesis";"Superpathway of mycolate biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis initiation (plant mitochondria)";"Mupirocin biosynthesis";"Gondoate biosynthesis (anaerobic)";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Biotin metabolism";"Oleate biosynthesis I (plants)";"8-amino-7-oxononanoate biosynthesis I";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acyl-CoA biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Petroselinate biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"";"Fatty acid biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Cis-vaccenate biosynthesis";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Oleate biosynthesis IV (anaerobic)"
LHES011735-PA	13	Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553	"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs"
LHES007354-PA	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
LHES015012-PA	3	Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282	"HS-GAG degradation";"Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B"
LHES001326-PA	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
LHES011864-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
LHES012206-PA	6	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
LHES005454-PA	22	Reactome: R-HSA-5467348;Reactome: R-HSA-6811558;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-432142;Reactome: R-HSA-5467340;Reactome: R-HSA-5358747;Reactome: R-HSA-5675221;Reactome: R-HSA-68877;Reactome: R-HSA-5467337;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-5673000;Reactome: R-HSA-141444;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-389513;Reactome: R-HSA-5358749	"Truncations of AMER1 destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"AXIN missense mutants destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Mitotic Prometaphase";"APC truncation mutants have impaired AXIN binding";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"RAF activation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated"
LHES005830-PA	4	Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
LHES012580-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
LHES002558-PA	2	Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
LHES006271-PA	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
LHES001753-PA	3	KEGG: 00643+3.7.1.2;Reactome: R-HSA-8963684;KEGG: 00350+3.7.1.2	"Styrene degradation";"Tyrosine catabolism";"Tyrosine metabolism"
LHES016734-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
LHES016612-PA	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
LHES010487-PA	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72695	"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex"
LHES016755-PA	1	Reactome: R-HSA-9640463	"Wax biosynthesis"
LHES001781-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
LHES000712-PA	9	Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693616	"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange"
LHES004848-PA	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
LHES016679-PA	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
LHES005648-PA	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
LHES014908-PA	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
LHES001377-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
LHES004342-PA	5	Reactome: R-HSA-4793954;Reactome: R-HSA-532668;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7919;MetaCyc: PWY-7918	"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (plants and animals)";"Protein N-glycosylation processing phase (yeast)"
LHES004237-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
LHES008801-PA	3	Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803	"tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II"
LHES008818-PA	1	Reactome: R-HSA-373752	"Netrin-1 signaling"
LHES007190-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
LHES008678-PA	1	Reactome: R-HSA-191859	"snRNP Assembly"
LHES006289-PA	1	Reactome: R-HSA-611105	"Respiratory electron transport"
LHES015431-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
LHES015076-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
LHES016456-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
LHES001152-PA	1	Reactome: R-HSA-8876725	"Protein methylation"
LHES010574-PA	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
LHES016838-PA	2	Reactome: R-HSA-416476;Reactome: R-HSA-389397	"G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors"
LHES016061-PA	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
LHES006489-PA	18	MetaCyc: PWY-7383;KEGG: 00710+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-561;KEGG: 00020+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-6969;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5690;KEGG: 00270+1.1.1.37;MetaCyc: PWY-1622;Reactome: R-HSA-70263;KEGG: 00720+1.1.1.37;MetaCyc: PWY-7115;KEGG: 00680+1.1.1.37;MetaCyc: PWY-6728;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5392	"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation in photosynthetic organisms";"Partial TCA cycle (obligate autotrophs)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism";"TCA cycle II (plants and fungi)";"Cysteine and methionine metabolism";"Formaldehyde assimilation I (serine pathway)";"Gluconeogenesis";"Carbon fixation pathways in prokaryotes";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Methane metabolism";"Methylaspartate cycle";"Glyoxylate and dicarboxylate metabolism";"Reductive TCA cycle II"
LHES011191-PA	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
LHES001581-PA	11	KEGG: 00230+3.1.3.5;MetaCyc: PWY-6596;KEGG: 00760+3.1.3.5;MetaCyc: PWY-6608;MetaCyc: PWY-7821;KEGG: 00240+3.1.3.5;MetaCyc: PWY-6607;MetaCyc: PWY-5695;MetaCyc: PWY-6606;MetaCyc: PWY-7185;MetaCyc: PWY-5381	"Purine metabolism";"Adenosine nucleotides degradation I";"Nicotinate and nicotinamide metabolism";"Guanosine nucleotides degradation III";"Tunicamycin biosynthesis";"Pyrimidine metabolism";"Guanosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation II";"UTP and CTP dephosphorylation I";"Pyridine nucleotide cycling (plants)"
LHES014027-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
LHES010496-PA	16	Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-8943723;Reactome: R-HSA-2559580;Reactome: R-HSA-8936459;Reactome: R-HSA-8948700;Reactome: R-HSA-2559585;Reactome: R-HSA-8986944;Reactome: R-HSA-8853884;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128	"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"Regulation of PTEN mRNA translation";"Oxidative Stress Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oncogene Induced Senescence";"Transcriptional Regulation by MECP2";"Transcriptional Regulation by VENTX";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"MAPK6/MAPK4 signaling"
LHES003744-PA	4	Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase"
LHES014427-PA	5	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7922	"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)"
LHES012576-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
LHES007491-PA	3	MetaCyc: PWY-6700;MetaCyc: PWY-8106;Reactome: R-HSA-6782315	"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol"
LHES012158-PA	7	KEGG: 00670+6.3.4.3;MetaCyc: PWY-3841;MetaCyc: PWY-1722;KEGG: 00720+6.3.4.3;MetaCyc: PWY-2161;MetaCyc: PWY-2201;Reactome: R-HSA-196757	"One carbon pool by folate";"Folate transformations II (plants)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Folate polyglutamylation";"Folate transformations I";"Metabolism of folate and pterines"
LHES001430-PA	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
LHES009018-PA	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
LHES011126-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
LHES007791-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
LHES014594-PA	26	Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-389960;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-190861;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-437239;Reactome: R-HSA-389977;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-9609690	"Cilium Assembly";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"Formation of tubulin folding intermediates by CCT/TriC";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"Gap junction assembly";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Recycling pathway of L1";"Post-chaperonin tubulin folding pathway";"MHC class II antigen presentation";"Kinesins";"HCMV Early Events"
LHES014829-PA	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
LHES010116-PA	6	Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-176187	"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of ATR in response to replication stress"
LHES002066-PA	2	Reactome: R-HSA-73614;Reactome: R-HSA-73621	"Pyrimidine salvage";"Pyrimidine catabolism"
LHES009339-PA	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
LHES011717-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES015781-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
LHES013584-PA	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
LHES013861-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
LHES009822-PA	1	Reactome: R-HSA-8949613	"Cristae formation"
LHES000333-PA	4	Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878	"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-mediated anterograde transport"
LHES001486-PA	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
LHES016927-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
LHES011347-PA	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
LHES003909-PA	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
LHES001058-PA	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
LHES006357-PA	1	Reactome: R-HSA-6804760	"Regulation of TP53 Activity through Methylation"
LHES008447-PA	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
LHES008469-PA	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
LHES010502-PA	6	Reactome: R-HSA-6803205;Reactome: R-HSA-6803211;Reactome: R-HSA-139915;Reactome: R-HSA-6804759;Reactome: R-HSA-6803204;Reactome: R-HSA-6803207	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Death Receptors and Ligands";"Activation of PUMA and translocation to mitochondria";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Caspase Activators and Caspases"
LHES008769-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
LHES000080-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
LHES006995-PA	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
LHES002134-PA	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
LHES001974-PA	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
LHES008834-PA	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
LHES006936-PA	3	Reactome: R-HSA-2024101;Reactome: R-HSA-2206302;Reactome: R-HSA-2024096	"CS/DS degradation";"MPS I - Hurler syndrome";"HS-GAG degradation"
LHES004867-PA	16	Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition"
LHES012219-PA	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
LHES007295-PA	6	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
LHES016011-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
LHES017126-PA	4	KEGG: 00750+1.4.3.5;MetaCyc: PWY-7204;MetaCyc: PWY-7282;Reactome: R-HSA-964975	"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate"
LHES012672-PA	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
LHES015864-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
LHES010837-PA	1	Reactome: R-HSA-191859	"snRNP Assembly"
LHES001332-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
LHES005467-PA	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
LHES003932-PA	2	Reactome: R-HSA-416476;Reactome: R-HSA-375280	"G alpha (q) signalling events";"Amine ligand-binding receptors"
LHES000116-PA	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
LHES004635-PA	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
LHES011069-PA	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
LHES003369-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
LHES003474-PA	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
LHES002436-PA	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
LHES000204-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
LHES007682-PA	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
LHES001760-PA	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
LHES015259-PA	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
LHES009429-PA	12	Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-6804756;Reactome: R-HSA-75955	"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Elongation"
LHES014198-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
LHES000153-PA	11	KEGG: 00910+6.3.1.2;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6549;Reactome: R-HSA-8964539;Reactome: R-HSA-210455;KEGG: 00630+6.3.1.2;MetaCyc: PWY-381;MetaCyc: PWY-6963;MetaCyc: PWY-6964;MetaCyc: PWY-5675;KEGG: 00250+6.3.1.2	"Nitrogen metabolism";"Arginine biosynthesis";"L-glutamine biosynthesis III";"Glutamate and glutamine metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle I";"Ammonia assimilation cycle II";"Nitrate reduction V (assimilatory)";"Alanine, aspartate and glutamate metabolism"
LHES006375-PA	5	Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-3232118	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"SUMOylation of transcription factors"
LHES008472-PA	7	Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-69202	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition"
LHES009617-PA	14	MetaCyc: PWY-6969;MetaCyc: PWY-561;KEGG: 00020+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-6728;KEGG: 00720+1.3.5.1;MetaCyc: PWY-7254;Reactome: R-HSA-611105;MetaCyc: PWY-4302;KEGG: 00190+1.3.5.1;KEGG: 00650+1.3.5.1;MetaCyc: PWY-7279;Reactome: R-HSA-71403;MetaCyc: PWY-5690	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Aerobic respiration I (cytochrome c)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"Respiratory electron transport";"Aerobic respiration III (alternative oxidase pathway)";"Oxidative phosphorylation";"Butanoate metabolism";"Aerobic respiration II (cytochrome c) (yeast)";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)"
LHES014370-PA	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
LHES010535-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
LHES003050-PA	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
LHES016507-PA	7	KEGG: 00220+3.5.1.2;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2;MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897	"Arginine biosynthesis";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes"
LHES000666-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
LHES008668-PA	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
LHES004726-PA	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
LHES006756-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES006706-PA	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
LHES016536-PA	1	Reactome: R-HSA-8951664	"Neddylation"
LHES001263-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
LHES009542-PA	8	Reactome: R-HSA-9613354;Reactome: R-HSA-380972;Reactome: R-HSA-1445148;Reactome: R-HSA-6804756;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-9619483;Reactome: R-HSA-2151209	"Lipophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Activation of AMPK downstream of NMDARs";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation"
LHES014009-PA	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
LHES001112-PA	10	Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-2565942;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-5684264	"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Regulation of PLK1 Activity at G2/M Transition";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"MAP3K8 (TPL2)-dependent MAPK1/3 activation"
LHES002315-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
LHES008854-PA	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
LHES014304-PA	8	Reactome: R-HSA-182218;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9636467;Reactome: R-HSA-167590	"Nef Mediated CD8 Down-regulation";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Blockage of phagosome acidification";"Nef Mediated CD4 Down-regulation"
LHES016498-PA	2	Reactome: R-HSA-176187;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
LHES005245-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
LHES001996-PA	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
LHES001918-PA	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
LHES005156-PA	8	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway"
LHES015921-PA	6	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Neutrophil degranulation";"ROS and RNS production in phagocytes"
LHES003760-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
LHES003701-PA	30	Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-2644606;Reactome: R-HSA-400253;Reactome: R-HSA-2894862;Reactome: R-HSA-2644607;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-2122947;Reactome: R-HSA-9604323;Reactome: R-HSA-69231;Reactome: R-HSA-195253;Reactome: R-HSA-5684264;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-1170546;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-2565942;Reactome: R-HSA-5610785;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-917937;Reactome: R-HSA-174113	"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Circadian Clock";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"NOTCH1 Intracellular Domain Regulates Transcription";"Negative regulation of NOTCH4 signaling";"Cyclin D associated events in G1";"Degradation of beta-catenin by the destruction complex";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Prolactin receptor signaling";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"GLI3 is processed to GLI3R by the proteasome";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"Iron uptake and transport";"SCF-beta-TrCP mediated degradation of Emi1"
LHES004266-PA	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
LHES014788-PA	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
LHES016661-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
LHES005653-PA	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
LHES007464-PA	9	Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-191859;Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"snRNP Assembly";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock"
LHES014848-PA	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
LHES014583-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
LHES001659-PA	27	Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-4615885;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-191859	"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly"
LHES003851-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
LHES004666-PA	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
LHES013622-PA	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
LHES011056-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
LHES011418-PA	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
LHES012228-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
LHES007974-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
LHES013216-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
LHES000528-PA	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
LHES011464-PA	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
LHES016654-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
LHES004196-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
LHES005071-PA	3	Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (i) signalling events";"G alpha (q) signalling events";"Peptide ligand-binding receptors"
LHES015442-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
LHES000853-PA	13	Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-6791226	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol"
LHES011953-PA	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
LHES012427-PA	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
LHES015773-PA	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
LHES007312-PA	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
LHES009437-PA	14	MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-6433;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7724	"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
LHES006156-PA	13	MetaCyc: PWY-5913;KEGG: 00720+4.2.1.2;KEGG: 00020+4.2.1.2;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-7254;MetaCyc: PWY-6728;KEGG: 00620+4.2.1.2;MetaCyc: PWY-561;MetaCyc: PWY-6969;MetaCyc: PWY-8086;MetaCyc: PWY-5392;MetaCyc: PWY-7384	"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"Pyruvate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)"
LHES004648-PA	6	Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-6791226	"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
LHES011628-PA	6	MetaCyc: PWY-6907;MetaCyc: PWY-6898;Reactome: R-HSA-196819;MetaCyc: PWY-7356;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6908	"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage III";"Vitamin B1 (thiamin) metabolism";"Thiamine salvage IV (yeast)";"Thiamine metabolism";"Thiamine diphosphate biosynthesis IV (eukaryotes)"
LHES000362-PA	13	Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553	"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs"
LHES011430-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
LHES008140-PA	1	Reactome: R-HSA-611105	"Respiratory electron transport"
LHES016359-PA	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
LHES003995-PA	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
LHES003560-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
LHES004832-PA	2	Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
LHES014256-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
LHES003933-PA	2	Reactome: R-HSA-375280;Reactome: R-HSA-416476	"Amine ligand-binding receptors";"G alpha (q) signalling events"
LHES002491-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
LHES015918-PA	6	MetaCyc: PWY-5941;KEGG: 00500+2.4.1.1;Reactome: R-HSA-70221;MetaCyc: PWY-6731;MetaCyc: PWY-6737;MetaCyc: PWY-7238	"Glycogen degradation II";"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)";"Starch degradation III";"Starch degradation V";"Sucrose biosynthesis II"
LHES012227-PA	13	Reactome: R-HSA-3000171;Reactome: R-HSA-3560801;Reactome: R-HSA-3560783;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-3000178;Reactome: R-HSA-2024096;Reactome: R-HSA-2022928;Reactome: R-HSA-419037;Reactome: R-HSA-1971475;Reactome: R-HSA-975634;Reactome: R-HSA-216083;Reactome: R-HSA-4420332	"Non-integrin membrane-ECM interactions";"Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"ECM proteoglycans";"HS-GAG degradation";"HS-GAG biosynthesis";"NCAM1 interactions";"A tetrasaccharide linker sequence is required for GAG synthesis";"Retinoid metabolism and transport";"Integrin cell surface interactions";"Defective B3GALT6 causes EDSP2 and SEMDJL1"
LHES000113-PA	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
LHES001345-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
LHES015514-PA	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
LHES013930-PA	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
LHES012728-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
LHES008904-PA	1	Reactome: R-HSA-211981	"Xenobiotics"
LHES002570-PA	16	Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-156827	"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression"
LHES000383-PA	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
LHES005684-PA	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
LHES012321-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
LHES009044-PA	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
LHES016230-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
LHES001660-PA	27	Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-3108214	"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins"
LHES010500-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
LHES006479-PA	1	Reactome: R-HSA-8964539	"Glutamate and glutamine metabolism"
LHES011882-PA	26	Reactome: R-HSA-5656121;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-174414;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-69183;Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-69205;Reactome: R-HSA-8866654;Reactome: R-HSA-174417;Reactome: R-HSA-5358606;Reactome: R-HSA-1362277;Reactome: R-HSA-174437;Reactome: R-HSA-4615885;Reactome: R-HSA-5358565;Reactome: R-HSA-6804114;Reactome: R-HSA-5651801	"Translesion synthesis by POLI";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Processive synthesis on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Polymerase switching";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Processive synthesis on the lagging strand";"Dual incision in TC-NER";"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"G1/S-Specific Transcription";"E3 ubiquitin ligases ubiquitinate target proteins";"Telomere C-strand (Lagging Strand) Synthesis";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Transcription of E2F targets under negative control by DREAM complex";"Removal of the Flap Intermediate from the C-strand";"SUMOylation of DNA replication proteins";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"PCNA-Dependent Long Patch Base Excision Repair"
LHES014418-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
LHES002769-PA	56	Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-187577;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-5687128;Reactome: R-HSA-5607761	"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"ER-Phagosome pathway";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"SCF(Skp2)-mediated degradation of p27/p21";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"MAPK6/MAPK4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling"
LHES015470-PA	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
LHES009164-PA	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
LHES001684-PA	28	Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-5696395;Reactome: R-HSA-3371511;Reactome: R-HSA-174437;Reactome: R-HSA-5358606;Reactome: R-HSA-68962;Reactome: R-HSA-5651801;Reactome: R-HSA-5358565;Reactome: R-HSA-912446;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-6783310;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-69166;Reactome: R-HSA-5693607;Reactome: R-HSA-3371453;Reactome: R-HSA-6804756;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-110320	"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"Formation of Incision Complex in GG-NER";"HSF1 activation";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Activation of the pre-replicative complex";"PCNA-Dependent Long Patch Base Excision Repair";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Meiotic recombination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Fanconi Anemia Pathway";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Removal of the Flap Intermediate";"Processing of DNA double-strand break ends";"Regulation of HSF1-mediated heat shock response";"Regulation of TP53 Activity through Phosphorylation";"Dual incision in TC-NER";"Translesion synthesis by POLK";"Translesion Synthesis by POLH"
LHES014723-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
LHES014863-PA	16	Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-156827	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression"
LHES005160-PA	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
LHES006395-PA	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
LHES001370-PA	4	Reactome: R-HSA-71032;Reactome: R-HSA-3359478;Reactome: R-HSA-196741;Reactome: R-HSA-3359475	"Propionyl-CoA catabolism";"Defective MUT causes methylmalonic aciduria mut type";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMAA causes methylmalonic aciduria type cblA"
LHES013318-PA	12	MetaCyc: PWY-5690;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-7384;MetaCyc: PWY-5392;MetaCyc: PWY-6969;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6728	"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Methylaspartate cycle"
LHES002042-PA	9	Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167162	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape"
LHES015646-PA	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
LHES001603-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
LHES010771-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
LHES003106-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
LHES009933-PA	27	Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464	"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins"
LHES003032-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
LHES012769-PA	1	Reactome: R-HSA-71288	"Creatine metabolism"
LHES011852-PA	1	Reactome: R-HSA-6783984	"Glycine degradation"
LHES004945-PA	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
LHES008304-PA	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
LHES011211-PA	9	Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695	"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events"
LHES009815-PA	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
LHES001995-PA	6	Reactome: R-HSA-983168;Reactome: R-HSA-2173788;Reactome: R-HSA-8863795;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of TGF-beta receptor signaling";"Downregulation of ERBB2 signaling";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Protein ubiquitination"
LHES010205-PA	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
LHES000161-PA	5	MetaCyc: PWY-6853;Reactome: R-HSA-389661;Reactome: R-HSA-70688;KEGG: 00330+1.2.1.88;KEGG: 00250+1.2.1.88	"Ethylene biosynthesis II (microbes)";"Glyoxylate metabolism and glycine degradation";"Proline catabolism";"Arginine and proline metabolism";"Alanine, aspartate and glutamate metabolism"
LHES007178-PA	3	Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine"
LHES009794-PA	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
LHES016058-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
LHES012377-PA	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
LHES004954-PA	13	Reactome: R-HSA-2871796;Reactome: R-HSA-2424491;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;Reactome: R-HSA-2029485;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-202433;Reactome: R-HSA-9027277;Reactome: R-HSA-2871809	"FCERI mediated MAPK activation";"DAP12 signaling";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Role of phospholipids in phagocytosis";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Generation of second messenger molecules";"Erythropoietin activates Phospholipase C gamma (PLCG)";"FCERI mediated Ca+2 mobilization"
LHES002706-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
LHES008999-PA	14	Reactome: R-HSA-8986944;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-8934593;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-426486;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897	"Transcriptional Regulation by MECP2";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"Small interfering RNA (siRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes"
LHES011860-PA	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
LHES008899-PA	18	Reactome: R-HSA-1482839;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482801;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7416;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482925	"Acyl chain remodelling of PE";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Acyl chain remodelling of PS";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Synthesis of PA";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Arachidonic acid metabolism";"Acyl chain remodelling of PG"
LHES000369-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
LHES013352-PA	5	Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
LHES006994-PA	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
LHES015816-PA	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
LHES008238-PA	21	Reactome: R-HSA-937041;Reactome: R-HSA-168927;Reactome: R-HSA-5603029;Reactome: R-HSA-5603027;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-1810476;Reactome: R-HSA-168638;Reactome: R-HSA-5357905;Reactome: R-HSA-445989;Reactome: R-HSA-5357956;Reactome: R-HSA-2871837;Reactome: R-HSA-933542;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-5602636;Reactome: R-HSA-5684264;Reactome: R-HSA-1169091;Reactome: R-HSA-933543;Reactome: R-HSA-937039;Reactome: R-HSA-975144	"IKK complex recruitment mediated by RIP1";"TICAM1, RIP1-mediated IKK complex recruitment";"IkBA variant leads to EDA-ID";"IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)";"Interleukin-1 signaling";"ER-Phagosome pathway";"RIP-mediated NFkB activation via ZBP1";"NOD1/2 Signaling Pathway";"Regulation of TNFR1 signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TNFR1-induced NFkappaB signaling pathway";"FCERI mediated NF-kB activation";"TRAF6 mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"IKBKB deficiency causes SCID";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Activation of NF-kappaB in B cells";"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10";"IRAK1 recruits IKK complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"
LHES003389-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
LHES012409-PA	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
LHES016779-PA	13	Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
LHES005474-PA	4	KEGG: 00791+3.5.1.5;KEGG: 00220+3.5.1.5;KEGG: 00230+3.5.1.5;MetaCyc: PWY-5704	"Atrazine degradation";"Arginine biosynthesis";"Purine metabolism";"Urea degradation II"
LHES006244-PA	6	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
LHES006990-PA	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
LHES002268-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
LHES007814-PA	2	Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
LHES015621-PA	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
LHES008527-PA	2	MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70	"Pseudouridine degradation";"Pyrimidine metabolism"
LHES001479-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
LHES008576-PA	27	Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-4551638	"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins"
LHES015327-PA	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
LHES001360-PA	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
LHES012720-PA	5	Reactome: R-HSA-2871796;Reactome: R-HSA-450321;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341	"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors"
LHES000340-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
LHES010279-PA	3	Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+2.10.1.1	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
LHES011999-PA	13	Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits"
LHES005010-PA	27	Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-180910	"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs"
LHES002912-PA	5	Reactome: R-HSA-1482801;Reactome: R-HSA-1482788;Reactome: R-HSA-1482922;Reactome: R-HSA-1482839;Reactome: R-HSA-1483115	"Acyl chain remodelling of PS";"Acyl chain remodelling of PC";"Acyl chain remodelling of PI";"Acyl chain remodelling of PE";"Hydrolysis of LPC"
LHES006927-PA	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
LHES008756-PA	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
LHES005945-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
LHES002254-PA	7	MetaCyc: PWY-6605;MetaCyc: PWY-6610;MetaCyc: PWY-7807;Reactome: R-HSA-74217;MetaCyc: PWY-7805;Reactome: R-HSA-6798695;KEGG: 00230+2.4.2.7	"Adenine and adenosine salvage II";"Adenine salvage";"Glyphosate degradation III";"Purine salvage";"(aminomethyl)phosphonate degradation";"Neutrophil degranulation";"Purine metabolism"
LHES003815-PA	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
LHES001705-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES003264-PA	6	MetaCyc: PWY-6317;KEGG: 00052+2.7.7.12;Reactome: R-HSA-70370;KEGG: 00520+2.7.7.12;Reactome: R-HSA-5609978;MetaCyc: PWY-6527	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Galactose catabolism";"Amino sugar and nucleotide sugar metabolism";"Defective GALT can cause Galactosemia";"Stachyose degradation"
LHES011205-PA	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
LHES015475-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
LHES001019-PA	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
LHES014173-PA	1	Reactome: R-HSA-211981	"Xenobiotics"
LHES001679-PA	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
LHES001362-PA	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
LHES002775-PA	4	KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268;MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49	"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Entner-Doudoroff pathway I";"Glutathione metabolism"
LHES006673-PA	6	KEGG: 00710+5.1.3.1;KEGG: 00040+5.1.3.1;MetaCyc: PWY-1861;KEGG: 00030+5.1.3.1;MetaCyc: PWY-5723;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose and glucuronate interconversions";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Rubisco shunt";"Pentose phosphate pathway"
LHES009911-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
LHES011796-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
LHES005936-PA	5	Reactome: R-HSA-1362409;Reactome: R-HSA-211976;Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-196108	"Mitochondrial iron-sulfur cluster biogenesis";"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis"
LHES008545-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
LHES015876-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
LHES005276-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
LHES008787-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
LHES011238-PA	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
LHES010536-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
LHES005551-PA	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
LHES009675-PA	52	Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-8939236;Reactome: R-HSA-8939902;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-8852276;Reactome: R-HSA-5362768;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-9010553	"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX2 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"Neddylation";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"Degradation of DVL";"ABC-family proteins mediated transport";"Regulation of expression of SLITs and ROBOs"
LHES010012-PA	6	Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-380994	"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
LHES006623-PA	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
LHES010945-PA	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway"
LHES010691-PA	8	Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-69166	"DNA replication initiation";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate"
LHES005769-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
LHES000707-PA	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
LHES002564-PA	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
LHES011070-PA	3	Reactome: R-HSA-8957275;Reactome: R-HSA-5362798;Reactome: R-HSA-381426	"Post-translational protein phosphorylation";"Release of Hh-Np from the secreting cell";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
LHES001620-PA	1	Reactome: R-HSA-191859	"snRNP Assembly"
LHES014888-PA	1	Reactome: R-HSA-264876	"Insulin processing"
LHES010722-PA	3	KEGG: 00970+6.1.1.19;Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
LHES011266-PA	1	Reactome: R-HSA-427589	"Type II Na+/Pi cotransporters"
LHES005106-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
LHES000673-PA	6	Reactome: R-HSA-72163;MetaCyc: PWY-7511;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823	"mRNA Splicing - Major Pathway";"Protein ubiquitination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex"
LHES010247-PA	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
LHES017224-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
LHES012716-PA	26	Reactome: R-HSA-9614657;Reactome: R-HSA-5621575;Reactome: R-HSA-8941856;Reactome: R-HSA-381340;Reactome: R-HSA-9617629;Reactome: R-HSA-2122947;Reactome: R-HSA-9018519;Reactome: R-HSA-1368082;Reactome: R-HSA-210744;Reactome: R-HSA-2644606;Reactome: R-HSA-3214847;Reactome: R-HSA-1989781;Reactome: R-HSA-3134973;Reactome: R-HSA-933541;Reactome: R-HSA-1912408;Reactome: R-HSA-2894862;Reactome: R-HSA-400253;Reactome: R-HSA-9013695;Reactome: R-HSA-3899300;Reactome: R-HSA-201722;Reactome: R-HSA-918233;Reactome: R-HSA-5617472;Reactome: R-HSA-9013508;Reactome: R-HSA-1234158;Reactome: R-HSA-8866907;Reactome: R-HSA-3371568	"FOXO-mediated transcription of cell death genes";"CD209 (DC-SIGN) signaling";"RUNX3 regulates NOTCH signaling";"Transcriptional regulation of white adipocyte differentiation";"Regulation of FOXO transcriptional activity by acetylation";"NOTCH1 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"RORA activates gene expression";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HATs acetylate histones";"PPARA activates gene expression";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"TRAF6 mediated IRF7 activation";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Circadian Clock";"NOTCH4 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"Formation of the beta-catenin:TCF transactivating complex";"TRAF3-dependent IRF activation pathway";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression by Hypoxia-inducible Factor";"Activation of the TFAP2 (AP-2) family of transcription factors";"Attenuation phase"
LHES007267-PA	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
LHES016778-PA	40	KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-5136;MetaCyc: PWY-7401;KEGG: 00592+4.2.1.17;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7656;MetaCyc: PWY-6583;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7726;MetaCyc: PWY-6863;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;MetaCyc: PWY-7654;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;MetaCyc: PWY-5109;MetaCyc: PWY-6435;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7007;KEGG: 00410+4.2.1.17;MetaCyc: PWY-1361;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;MetaCyc: PWY-6946;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7216;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;MetaCyc: PWY-7606;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;MetaCyc: PWY-6944;MetaCyc: PWY-7779;KEGG: 00360+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35	"Geraniol degradation";"Pyruvate fermentation to butanol II (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"alpha-Linolenic acid metabolism";"Aminobenzoate degradation";"Spodoptera littoralis pheromone biosynthesis";"Pyruvate fermentation to butanol I";"Propanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Pyruvate fermentation to hexanol (engineered)";"Benzoate degradation";"Glutaryl-coa degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fatty acid degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fermentation to 2-methylbutanoate";"4-hydroxybenzoate biosynthesis III (plants)";"Toluene degradation";"Methyl ketone biosynthesis (engineered)";"beta-Alanine metabolism";"Benzoyl-coa degradation I (aerobic)";"Butanoate metabolism";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Lysine degradation";"Valine, leucine and isoleucine degradation";"Limonene and pinene degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Carbon fixation pathways in prokaryotes";"Fatty acid salvage";"Fatty acid elongation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Caprolactam degradation";"2-methylpropene degradation";"Androstenedione degradation";"Methyl tert-butyl ether degradation";"Phenylalanine metabolism";"Tryptophan metabolism"
LHES007455-PA	14	Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-426486;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-8934593;Reactome: R-HSA-203927;Reactome: R-HSA-8986944;Reactome: R-HSA-426496;Reactome: R-HSA-9018519	"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Small interfering RNA (siRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Regulation of RUNX1 Expression and Activity";"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression"
LHES001842-PA	5	Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-164843;Reactome: R-HSA-6798695;Reactome: R-HSA-1834949	"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"2-LTR circle formation";"Neutrophil degranulation";"Cytosolic sensors of pathogen-associated DNA"
LHES006928-PA	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
LHES013376-PA	11	KEGG: 00620+6.4.1.2;MetaCyc: PWY-6679;Reactome: R-HSA-2426168;MetaCyc: PWY-5966-1;KEGG: 00720+6.4.1.2;KEGG: 00640+6.4.1.2;Reactome: R-HSA-196780;Reactome: R-HSA-200425;KEGG: 00061+6.4.1.2;KEGG: 00254+6.4.1.2;Reactome: R-HSA-163765	"Pyruvate metabolism";"Jadomycin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Biotin transport and metabolism";"Carnitine metabolism";"Fatty acid biosynthesis";"Aflatoxin biosynthesis";"ChREBP activates metabolic gene expression"
LHES000373-PA	7	MetaCyc: PWY-7511;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232	"Protein ubiquitination";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
LHES015745-PA	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
LHES016007-PA	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
LHES007864-PA	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
LHES000507-PA	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
LHES000378-PA	2	Reactome: R-HSA-392154;Reactome: R-HSA-1222556	"Nitric oxide stimulates guanylate cyclase";"ROS and RNS production in phagocytes"
LHES005473-PA	4	KEGG: 00230+3.5.1.5;MetaCyc: PWY-5704;KEGG: 00791+3.5.1.5;KEGG: 00220+3.5.1.5	"Purine metabolism";"Urea degradation II";"Atrazine degradation";"Arginine biosynthesis"
LHES008951-PA	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
LHES004167-PA	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
LHES007681-PA	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
LHES012103-PA	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
LHES011812-PA	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
LHES007616-PA	5	Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-5694530	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER"
LHES016297-PA	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
LHES009190-PA	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
LHES017207-PA	7	MetaCyc: PWY-6367;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;MetaCyc: PWY-6351	"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
LHES003914-PA	1	Reactome: R-HSA-8951664	"Neddylation"
LHES010230-PA	2	Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
LHES008692-PA	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
LHES010458-PA	2	Reactome: R-HSA-70171;Reactome: R-HSA-70263	"Glycolysis";"Gluconeogenesis"
LHES000838-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
LHES002929-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
LHES000420-PA	5	Reactome: R-HSA-5083630;Reactome: R-HSA-1912420;Reactome: R-HSA-350054;Reactome: R-HSA-1912399;Reactome: R-HSA-1912408	"Defective LFNG causes SCDO3";"Pre-NOTCH Processing in Golgi";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Pre-NOTCH Transcription and Translation"
LHES010994-PA	3	Reactome: R-HSA-1660662;KEGG: 00600+3.1.4.12;MetaCyc: PWY-7277	"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Sphingolipid biosynthesis (mammals)"
LHES005272-PA	5	Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73772	"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape"
LHES010213-PA	4	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379726;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation"
LHES008290-PA	12	MetaCyc: PWY-7384;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5392;MetaCyc: PWY-6728;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5	"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes"
LHES013374-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
LHES011609-PA	2	KEGG: 00260+1.4.4.2;Reactome: R-HSA-6783984	"Glycine, serine and threonine metabolism";"Glycine degradation"
LHES000913-PA	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
LHES011148-PA	4	Reactome: R-HSA-390247;Reactome: R-HSA-9033241;KEGG: 00410+4.1.1.9;KEGG: 00640+4.1.1.9	"Beta-oxidation of very long chain fatty acids";"Peroxisomal protein import";"beta-Alanine metabolism";"Propanoate metabolism"
LHES010097-PA	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
LHES013481-PA	2	Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2	"Glycine degradation";"Glycine, serine and threonine metabolism"
LHES015476-PA	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
LHES005252-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
LHES003941-PA	12	Reactome: R-HSA-5250924;Reactome: R-HSA-1912408;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-73762;Reactome: R-HSA-210744;Reactome: R-HSA-3214847;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856	"B-WICH complex positively regulates rRNA expression";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"RNA Polymerase I Transcription Initiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"HATs acetylate histones";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling"
LHES010085-PA	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
LHES006045-PA	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
LHES007103-PA	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
LHES002132-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
LHES011641-PA	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
LHES017251-PA	4	KEGG: 00250+6.3.4.4;MetaCyc: PWY-7219;KEGG: 00230+6.3.4.4;Reactome: R-HSA-73817	"Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis"
LHES002936-PA	26	Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-3214847;Reactome: R-HSA-1989781;Reactome: R-HSA-933541;Reactome: R-HSA-3134973;Reactome: R-HSA-2894862;Reactome: R-HSA-400253;Reactome: R-HSA-1912408;Reactome: R-HSA-9614657;Reactome: R-HSA-8941856;Reactome: R-HSA-5621575;Reactome: R-HSA-381340;Reactome: R-HSA-2122947;Reactome: R-HSA-9018519;Reactome: R-HSA-1368082;Reactome: R-HSA-9617629;Reactome: R-HSA-9013508;Reactome: R-HSA-5617472;Reactome: R-HSA-1234158;Reactome: R-HSA-8866907;Reactome: R-HSA-3371568;Reactome: R-HSA-9013695;Reactome: R-HSA-3899300;Reactome: R-HSA-918233;Reactome: R-HSA-201722	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"HATs acetylate histones";"PPARA activates gene expression";"TRAF6 mediated IRF7 activation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Circadian Clock";"Pre-NOTCH Transcription and Translation";"FOXO-mediated transcription of cell death genes";"RUNX3 regulates NOTCH signaling";"CD209 (DC-SIGN) signaling";"Transcriptional regulation of white adipocyte differentiation";"NOTCH1 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"RORA activates gene expression";"Regulation of FOXO transcriptional activity by acetylation";"NOTCH3 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression by Hypoxia-inducible Factor";"Activation of the TFAP2 (AP-2) family of transcription factors";"Attenuation phase";"NOTCH4 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"TRAF3-dependent IRF activation pathway";"Formation of the beta-catenin:TCF transactivating complex"
LHES011538-PA	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6811434	"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic"
LHES005246-PA	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
LHES016281-PA	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
LHES001797-PA	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
LHES008148-PA	3	Reactome: R-HSA-3065678;Reactome: R-HSA-3065676;Reactome: R-HSA-983168	"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"SUMO is conjugated to E1 (UBA2:SAE1)";"Antigen processing: Ubiquitination & Proteasome degradation"
LHES010595-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
LHES008416-PA	3	Reactome: R-HSA-1614603;Reactome: R-HSA-2408508;Reactome: R-HSA-1614558	"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine"
LHES002792-PA	7	Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-380972	"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Macroautophagy";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK"
LHES007637-PA	6	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
LHES000862-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
LHES004206-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
LHES010409-PA	13	KEGG: 00230+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7220;MetaCyc: PWY-7210;MetaCyc: PWY-6545;MetaCyc: PWY-7222;KEGG: 00480+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7198;MetaCyc: PWY-7227;MetaCyc: PWY-7226;KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1	"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Drug metabolism - other enzymes"
LHES010318-PA	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
LHES009401-PA	5	Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER"
LHES007241-PA	30	Reactome: R-HSA-2644607;Reactome: R-HSA-2894862;Reactome: R-HSA-400253;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-5684264;Reactome: R-HSA-5610785;Reactome: R-HSA-1170546;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-2565942;Reactome: R-HSA-8951664;Reactome: R-HSA-69231;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-917937	"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Circadian Clock";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"GLI3 is processed to GLI3R by the proteasome";"Prolactin receptor signaling";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Regulation of PLK1 Activity at G2/M Transition";"Neddylation";"Cyclin D associated events in G1";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"Iron uptake and transport"
LHES013241-PA	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
LHES002369-PA	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
LHES002488-PA	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
LHES016219-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
LHES012956-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
LHES014125-PA	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
LHES014484-PA	14	Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167243	"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery"
LHES013666-PA	9	Reactome: R-HSA-1474151;MetaCyc: PWY-5664;MetaCyc: PWY-5663;MetaCyc: PWY-7852;MetaCyc: PWY-7442;MetaCyc: PWY-6147;MetaCyc: PWY-6703;MetaCyc: PWY-6983;KEGG: 00790+3.5.4.16	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Drosopterin and aurodrosopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Preq0 biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Folate biosynthesis"
LHES015195-PA	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
LHES000328-PA	1	Reactome: R-HSA-5250924	"B-WICH complex positively regulates rRNA expression"
LHES007981-PA	2	Reactome: R-HSA-499943;KEGG: 00450+1.8.1.9	"Interconversion of nucleotide di- and triphosphates";"Selenocompound metabolism"
LHES014764-PA	5	Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5689901;Reactome: R-HSA-5693607	"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Metalloprotease DUBs";"Processing of DNA double-strand break ends"
LHES012706-PA	1	Reactome: R-HSA-196757	"Metabolism of folate and pterines"
LHES008687-PA	10	MetaCyc: PWY-7344;Reactome: R-HSA-70370;MetaCyc: PWY-6317;MetaCyc: PWY-7328;Reactome: R-HSA-5609977;MetaCyc: PWY-6527;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6397;KEGG: 00520+5.1.3.2;MetaCyc: PWY-3821	"UDP-alpha-D-galactose biosynthesis";"Galactose catabolism";"D-galactose degradation I (Leloir pathway)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Stachyose degradation";"Galactose metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification"
LHES006870-PA	6	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
LHES008754-PA	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
LHES001179-PA	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
LHES006758-PA	8	Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-380972	"Neutrophil degranulation";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Macroautophagy";"mTOR signalling";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK"
LHES017296-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES006260-PA	1	Reactome: R-HSA-611105	"Respiratory electron transport"
LHES002067-PA	2	Reactome: R-HSA-73621;Reactome: R-HSA-73614	"Pyrimidine catabolism";"Pyrimidine salvage"
LHES010700-PA	4	MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism"
LHES009851-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
LHES009311-PA	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
LHES014905-PA	1	KEGG: 00982+1.14.13.8	"Drug metabolism - cytochrome P450"
LHES003274-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
LHES000709-PA	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
LHES004426-PA	6	MetaCyc: PWY-6722;MetaCyc: PWY-5789;Reactome: R-HSA-196780;MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-4381	"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (bacteria and plants)"
LHES012491-PA	10	Reactome: R-HSA-4719377;MetaCyc: PWY-7661;MetaCyc: PWY-7979;KEGG: 00510+2.4.1.83;Reactome: R-HSA-4719360;Reactome: R-HSA-4717374;MetaCyc: PWY-7921;Reactome: R-HSA-162699;MetaCyc: PWY-7922;Reactome: R-HSA-913709	"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Protein N-glycosylation (Haloferax volcanii)";"Protein O-mannosylation III (mammals, core M3)";"N-Glycan biosynthesis";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Protein O-mannosylation I (yeast)";"Synthesis of dolichyl-phosphate mannose";"Protein O-mannosylation II (mammals, core M1 and core M2)";"O-linked glycosylation of mucins"
LHES010693-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
LHES011566-PA	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
LHES009485-PA	6	Reactome: R-HSA-381426;Reactome: R-HSA-5626467;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-8957275;Reactome: R-HSA-2173796	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"RHO GTPases activate IQGAPs";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Post-translational protein phosphorylation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"
LHES010258-PA	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
LHES000621-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
LHES006426-PA	11	Reactome: R-HSA-380320;Reactome: R-HSA-3371497;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-6807878;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-6811436;Reactome: R-HSA-2565942;Reactome: R-HSA-2132295	"Recruitment of NuMA to mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"COPI-mediated anterograde transport";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"COPI-independent Golgi-to-ER retrograde traffic";"Regulation of PLK1 Activity at G2/M Transition";"MHC class II antigen presentation"
LHES006367-PA	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
LHES006578-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
LHES002608-PA	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
LHES006313-PA	16	Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-9010553	"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs"
LHES014759-PA	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
LHES010257-PA	14	MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;Reactome: R-HSA-75876	"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs"
LHES004508-PA	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
LHES013253-PA	6	MetaCyc: PWY-7234;MetaCyc: PWY-6123;KEGG: 00230+3.5.4.10+2.1.2.3;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.3;MetaCyc: PWY-6124	"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis II"
LHES013734-PA	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
LHES002869-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
LHES009602-PA	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
LHES015822-PA	2	KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240	"Tryptophan metabolism";"Tryptophan catabolism"
LHES007483-PA	29	Reactome: R-HSA-3371453;Reactome: R-HSA-6804756;Reactome: R-HSA-69166;Reactome: R-HSA-5693607;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-6783310;Reactome: R-HSA-5656121;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-3108214;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-3371511;Reactome: R-HSA-5696395;Reactome: R-HSA-176187;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5358565;Reactome: R-HSA-5651801;Reactome: R-HSA-68962;Reactome: R-HSA-5358606;Reactome: R-HSA-174437	"Regulation of HSF1-mediated heat shock response";"Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate";"Processing of DNA double-strand break ends";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Fanconi Anemia Pathway";"Translesion synthesis by POLI";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"SUMOylation of DNA damage response and repair proteins";"Translesion synthesis by POLK";"Dual incision in TC-NER";"HSF1 activation";"Formation of Incision Complex in GG-NER";"Activation of ATR in response to replication stress";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"PCNA-Dependent Long Patch Base Excision Repair";"Activation of the pre-replicative complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Removal of the Flap Intermediate from the C-strand"
LHES000454-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
LHES005828-PA	4	KEGG: 00250+6.3.4.4;MetaCyc: PWY-7219;KEGG: 00230+6.3.4.4;Reactome: R-HSA-73817	"Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis"
LHES003444-PA	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
LHES001059-PA	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
LHES011562-PA	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
LHES006220-PA	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
LHES015400-PA	2	KEGG: 00760+6.3.1.5;Reactome: R-HSA-196807	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism"
LHES010365-PA	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
LHES009720-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
LHES002124-PA	26	Reactome: R-HSA-9013695;Reactome: R-HSA-3899300;Reactome: R-HSA-201722;Reactome: R-HSA-918233;Reactome: R-HSA-5617472;Reactome: R-HSA-9013508;Reactome: R-HSA-1234158;Reactome: R-HSA-8866907;Reactome: R-HSA-3371568;Reactome: R-HSA-9614657;Reactome: R-HSA-8941856;Reactome: R-HSA-5621575;Reactome: R-HSA-381340;Reactome: R-HSA-9617629;Reactome: R-HSA-1368082;Reactome: R-HSA-2122947;Reactome: R-HSA-9018519;Reactome: R-HSA-210744;Reactome: R-HSA-2644606;Reactome: R-HSA-3214847;Reactome: R-HSA-1989781;Reactome: R-HSA-3134973;Reactome: R-HSA-933541;Reactome: R-HSA-1912408;Reactome: R-HSA-2894862;Reactome: R-HSA-400253	"NOTCH4 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"Formation of the beta-catenin:TCF transactivating complex";"TRAF3-dependent IRF activation pathway";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression by Hypoxia-inducible Factor";"Activation of the TFAP2 (AP-2) family of transcription factors";"Attenuation phase";"FOXO-mediated transcription of cell death genes";"RUNX3 regulates NOTCH signaling";"CD209 (DC-SIGN) signaling";"Transcriptional regulation of white adipocyte differentiation";"Regulation of FOXO transcriptional activity by acetylation";"RORA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HATs acetylate histones";"PPARA activates gene expression";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"TRAF6 mediated IRF7 activation";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Circadian Clock"
LHES011728-PA	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
LHES017340-PA	3	MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2	"ATP biosynthesis";"Oxidative phosphorylation";"Photosynthesis"
LHES008821-PA	14	MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7782;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-8055;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;MetaCyc: PWY-7589;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-5981	"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III"
LHES016164-PA	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
LHES008237-PA	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
LHES011243-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
LHES005974-PA	3	Reactome: R-HSA-6807505;Reactome: R-HSA-749476;Reactome: R-HSA-76071	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
LHES016074-PA	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
LHES011551-PA	7	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-8957275;Reactome: R-HSA-114608;Reactome: R-HSA-381426;Reactome: R-HSA-140837	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events";"Post-translational protein phosphorylation";"Platelet degranulation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Intrinsic Pathway of Fibrin Clot Formation"
LHES006230-PA	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
LHES011036-PA	29	Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-6782135;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-167152;Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-113418;Reactome: R-HSA-5696395;Reactome: R-HSA-167160;Reactome: R-HSA-73772;Reactome: R-HSA-72086;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-73863;Reactome: R-HSA-75953	"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"Dual incision in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the Early Elongation Complex";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Promoter Escape";"mRNA Capping";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation"
LHES007177-PA	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
LHES017232-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
LHES004069-PA	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
LHES001548-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
LHES004783-PA	4	Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216	"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Collagen chain trimerization"
LHES008270-PA	2	Reactome: R-HSA-428890;KEGG: 04660+2.7.10.2	"Role of ABL in ROBO-SLIT signaling";"T cell receptor signaling pathway"
LHES002665-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
LHES007325-PA	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
LHES011719-PA	3	Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160	"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions"
LHES009161-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
LHES004174-PA	4	Reactome: R-HSA-975144;MetaCyc: PWY-7511;Reactome: R-HSA-937039;Reactome: R-HSA-9020702	"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Protein ubiquitination";"IRAK1 recruits IKK complex";"Interleukin-1 signaling"
LHES003928-PA	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
LHES013583-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
LHES017085-PA	6	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Ca2+ pathway"
LHES002073-PA	2	Reactome: R-HSA-181429;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
LHES013786-PA	4	KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922;Reactome: R-HSA-70688;MetaCyc: PWY-5737	"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis"
LHES001211-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
LHES004054-PA	7	Reactome: R-HSA-5628897;Reactome: R-HSA-5674400;Reactome: R-HSA-380972;Reactome: R-HSA-8854214;Reactome: R-HSA-198323;Reactome: R-HSA-1632852;Reactome: R-HSA-165181	"TP53 Regulates Metabolic Genes";"Constitutive Signaling by AKT1 E17K in Cancer";"Energy dependent regulation of mTOR by LKB1-AMPK";"TBC/RABGAPs";"AKT phosphorylates targets in the cytosol";"Macroautophagy";"Inhibition of TSC complex formation by PKB"
LHES004055-PA	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
LHES007572-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
LHES006515-PA	5	Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-163765;Reactome: R-HSA-75105;Reactome: R-HSA-2426168	"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)"
LHES013360-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
LHES003983-PA	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
LHES009317-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
LHES000253-PA	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
LHES006187-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
LHES008071-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES004699-PA	6	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
LHES002755-PA	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
LHES005399-PA	4	Reactome: R-HSA-373753;Reactome: R-HSA-186763;Reactome: R-HSA-428540;Reactome: R-HSA-4420097	"Nephrin family interactions";"Downstream signal transduction";"Activation of RAC1";"VEGFA-VEGFR2 Pathway"
LHES007603-PA	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
LHES016562-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
LHES002633-PA	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
LHES008278-PA	2	Reactome: R-HSA-196780;Reactome: R-HSA-3371599	"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency"
LHES003454-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
LHES001049-PA	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
LHES016849-PA	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
LHES000599-PA	6	Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress"
LHES005562-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
LHES001139-PA	17	Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-72764	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination"
LHES007967-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
LHES009238-PA	7	Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-166208	"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"mTOR signalling";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling"
LHES012816-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
LHES012909-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
LHES011383-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
LHES001761-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
LHES009660-PA	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
LHES010280-PA	3	KEGG: 00790+2.10.1.1;MetaCyc: PWY-6823;Reactome: R-HSA-947581	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
LHES003123-PA	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
LHES010104-PA	1	Reactome: R-HSA-5578775	"Ion homeostasis"
LHES004913-PA	7	MetaCyc: PWY-6545;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7185;MetaCyc: PWY-7184;KEGG: 00730+3.6.1.15;KEGG: 00230+3.6.1.15	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Thiamine metabolism";"Purine metabolism"
LHES015800-PA	7	Reactome: R-HSA-114608;Reactome: R-HSA-140837;Reactome: R-HSA-381426;Reactome: R-HSA-416476;Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-8957275	"Platelet degranulation";"Intrinsic Pathway of Fibrin Clot Formation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"G alpha (q) signalling events";"Peptide ligand-binding receptors";"G alpha (i) signalling events";"Post-translational protein phosphorylation"
LHES014311-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
LHES003255-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
LHES004594-PA	5	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling"
LHES008369-PA	5	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-6784531	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"tRNA processing in the nucleus"
LHES012054-PA	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
LHES008077-PA	3	KEGG: 00534+5.1.3.17;Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
LHES013799-PA	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
LHES002340-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
LHES008061-PA	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
LHES014807-PA	6	Reactome: R-HSA-8950505;Reactome: R-HSA-8862803;MetaCyc: PWY-6854;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201;Reactome: R-HSA-9615017	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"
LHES006421-PA	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
LHES007863-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
LHES001698-PA	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
LHES009403-PA	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
LHES016617-PA	8	Reactome: R-HSA-8950505;KEGG: 00030+2.2.1.2;MetaCyc: PWY-5723;Reactome: R-HSA-6791462;Reactome: R-HSA-71336;Reactome: R-HSA-6791055;Reactome: R-HSA-163754;MetaCyc: PWY-1861	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Pentose phosphate pathway";"Rubisco shunt";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Pentose phosphate pathway";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
LHES006348-PA	32	Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-8851708;Reactome: R-HSA-75953;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-168325;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-73776;Reactome: R-HSA-72163;Reactome: R-HSA-167158;Reactome: R-HSA-6803529;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-76042;Reactome: R-HSA-167238;Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-72203;Reactome: R-HSA-167172;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-6807505	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"Viral Messenger RNA Synthesis";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Promoter Escape";"mRNA Splicing - Major Pathway";"Formation of the HIV-1 Early Elongation Complex";"FGFR2 alternative splicing";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"Estrogen-dependent gene expression";"Processing of Capped Intron-Containing Pre-mRNA";"Transcription of the HIV genome";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA polymerase II transcribes snRNA genes"
LHES002590-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
LHES013610-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
LHES008690-PA	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
LHES000831-PA	8	Reactome: R-HSA-73614;MetaCyc: PWY-7193;Reactome: R-HSA-6798695;MetaCyc: PWY-7181;MetaCyc: PWY-7199;KEGG: 00240+3.5.4.5;MetaCyc: PWY-6556;KEGG: 00983+3.5.4.5	"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Neutrophil degranulation";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage II";"Drug metabolism - other enzymes"
LHES006212-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
LHES011059-PA	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
LHES007909-PA	6	MetaCyc: PWY-5789;MetaCyc: PWY-6722;Reactome: R-HSA-196780;MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-4381	"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"Biotin transport and metabolism";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (bacteria and plants)"
LHES016270-PA	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
LHES008993-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
LHES008135-PA	5	KEGG: 00240+6.3.4.2;MetaCyc: PWY-7177;MetaCyc: PWY-7176;Reactome: R-HSA-499943;MetaCyc: PWY-7185	"Pyrimidine metabolism";"UTP and CTP dephosphorylation II";"UTP and CTP de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation I"
LHES003280-PA	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
LHES006137-PA	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
LHES011181-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
LHES016853-PA	1	Reactome: R-HSA-379716	"Cytosolic tRNA aminoacylation"
LHES005241-PA	13	Reactome: R-HSA-1474244;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814;Reactome: R-HSA-3000171;Reactome: R-HSA-2214320;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-3000157;Reactome: R-HSA-3000178;Reactome: R-HSA-1442490;Reactome: R-HSA-419037;Reactome: R-HSA-186797;Reactome: R-HSA-216083	"Extracellular matrix organization";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes";"Non-integrin membrane-ECM interactions";"Anchoring fibril formation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Laminin interactions";"ECM proteoglycans";"Collagen degradation";"NCAM1 interactions";"Signaling by PDGF";"Integrin cell surface interactions"
LHES009850-PA	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
LHES002540-PA	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
LHES004038-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
LHES006487-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
LHES011761-PA	2	Reactome: R-HSA-877300;Reactome: R-HSA-909733	"Interferon gamma signaling";"Interferon alpha/beta signaling"
LHES010235-PA	2	Reactome: R-HSA-1222556;Reactome: R-HSA-392154	"ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase"
LHES017094-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
LHES005477-PA	9	Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167172	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome"
LHES001511-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
LHES014849-PA	5	Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73762	"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation"
LHES004166-PA	5	Reactome: R-HSA-5675221;Reactome: R-HSA-112409;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"Negative regulation of MAPK pathway";"RAF-independent MAPK1/3 activation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
LHES016240-PA	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
LHES003577-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
LHES006824-PA	5	MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis"
LHES011221-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
LHES001138-PA	1	Reactome: R-HSA-70635	"Urea cycle"
LHES000899-PA	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
LHES013018-PA	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
LHES011485-PA	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
LHES013681-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
LHES003391-PA	26	Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-389977;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-9609690;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-8955332;Reactome: R-HSA-389960	"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Gap junction assembly";"Mitotic Prometaphase";"Recycling pathway of L1";"Post-chaperonin tubulin folding pathway";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"HCMV Early Events";"Kinesins";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Formation of tubulin folding intermediates by CCT/TriC"
LHES005052-PA	9	MetaCyc: PWY-5743;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-5744;MetaCyc: PWY-7115;MetaCyc: PWY-6142;MetaCyc: PWY-5789	"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle"
LHES009922-PA	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
LHES003845-PA	7	Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-69202	"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition"
LHES011642-PA	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
LHES009505-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
LHES016415-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
LHES000580-PA	9	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection"
LHES016553-PA	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
LHES002525-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
LHES011841-PA	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
LHES011014-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
LHES015312-PA	2	MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24	"Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis"
LHES016137-PA	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
LHES013434-PA	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
LHES011082-PA	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
LHES011275-PA	12	Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-6804756;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-167246	"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript"
LHES009189-PA	1	Reactome: R-HSA-3295583	"TRP channels"
LHES009656-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
LHES009973-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
LHES015138-PA	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
LHES006967-PA	17	MetaCyc: PWY-7222;MetaCyc: PWY-7210;MetaCyc: PWY-7221;MetaCyc: PWY-7198;MetaCyc: PWY-7227;KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7224;MetaCyc: PWY-7176;MetaCyc: PWY-6545;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7197;MetaCyc: PWY-7205;MetaCyc: PWY-7187;MetaCyc: PWY-7184	"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
LHES008620-PA	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
LHES000377-PA	2	Reactome: R-HSA-392154;Reactome: R-HSA-1222556	"Nitric oxide stimulates guanylate cyclase";"ROS and RNS production in phagocytes"
LHES014221-PA	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
LHES005155-PA	9	Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-167172	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome"
LHES010070-PA	13	KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52	"Other glycan degradation";"Glycosaminoglycan degradation";"CS/DS degradation";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series"
LHES014286-PA	26	Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-389960;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-389977;Reactome: R-HSA-437239;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Post-chaperonin tubulin folding pathway";"Recycling pathway of L1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"HCMV Early Events";"Kinesins";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Mitotic Prometaphase"
LHES014981-PA	4	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination"
LHES005339-PA	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
LHES003031-PA	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
LHES001478-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
LHES002098-PA	5	Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
LHES016078-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
LHES005363-PA	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
LHES004019-PA	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
LHES007815-PA	2	Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
LHES016560-PA	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
LHES013322-PA	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
LHES016552-PA	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
LHES017137-PA	6	Reactome: R-HSA-6803207;Reactome: R-HSA-6803205;Reactome: R-HSA-6803211;Reactome: R-HSA-139915;Reactome: R-HSA-6803204;Reactome: R-HSA-6804759	"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Death Receptors and Ligands";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Regulation of TP53 Activity through Association with Co-factors"
LHES003542-PA	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
LHES011425-PA	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
LHES000936-PA	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
LHES007179-PA	9	KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822	"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)"
LHES013667-PA	6	Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-5626467;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2173796	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"RHO GTPases activate IQGAPs";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"
LHES014779-PA	10	KEGG: 00280+2.3.3.10;KEGG: 00900+2.3.3.10;KEGG: 00650+2.3.3.10;Reactome: R-HSA-1989781;KEGG: 00072+2.3.3.10;MetaCyc: PWY-922;MetaCyc: PWY-7571;MetaCyc: PWY-6174;MetaCyc: PWY-7524;MetaCyc: PWY-7391	"Valine, leucine and isoleucine degradation";"Terpenoid backbone biosynthesis";"Butanoate metabolism";"PPARA activates gene expression";"Synthesis and degradation of ketone bodies";"Mevalonate pathway I";"Ferrichrome A biosynthesis";"Mevalonate pathway II (archaea)";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)"
LHES001683-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
LHES014029-PA	8	Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-6783310;Reactome: R-HSA-2500257;Reactome: R-HSA-606279;Reactome: R-HSA-9648025	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Fanconi Anemia Pathway";"Resolution of Sister Chromatid Cohesion";"Deposition of new CENPA-containing nucleosomes at the centromere";"EML4 and NUDC in mitotic spindle formation"
LHES000991-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
LHES006206-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
LHES004317-PA	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
LHES004243-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
LHES001880-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
LHES000424-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
LHES014321-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
LHES016640-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
LHES014817-PA	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
LHES017125-PA	4	KEGG: 00750+1.4.3.5;MetaCyc: PWY-7282;MetaCyc: PWY-7204;Reactome: R-HSA-964975	"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate"
LHES005888-PA	7	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
LHES002036-PA	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
LHES005027-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
LHES012370-PA	57	Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-5687128;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-174154;Reactome: R-HSA-8939236;Reactome: R-HSA-8939902;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-187577;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-1236978;Reactome: R-HSA-6798695;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-4608870;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-5632684	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"MAPK6/MAPK4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdc20 mediated degradation of Securin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX2 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"SCF(Skp2)-mediated degradation of p27/p21";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Degradation of AXIN";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"ABC-family proteins mediated transport";"CLEC7A (Dectin-1) signaling";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neutrophil degranulation";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Asymmetric localization of PCP proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state"
LHES000592-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
LHES007883-PA	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
LHES012311-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
LHES001035-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
LHES007665-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
LHES006315-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES008236-PA	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
LHES011477-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
LHES003422-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
LHES005176-PA	2	Reactome: R-HSA-2243919;Reactome: R-HSA-1566948	"Crosslinking of collagen fibrils";"Elastic fibre formation"
LHES010273-PA	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554	"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
LHES013811-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
LHES005254-PA	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
LHES013484-PA	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76066	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
LHES011811-PA	4	Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947	"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
LHES004435-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
LHES015922-PA	3	Reactome: R-HSA-6811440;Reactome: R-HSA-8876198;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic"
LHES006309-PA	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
LHES005772-PA	5	Reactome: R-HSA-9013973;Reactome: R-HSA-933541;Reactome: R-HSA-918233;Reactome: R-HSA-936964;Reactome: R-HSA-936440	"TICAM1-dependent activation of IRF3/IRF7";"TRAF6 mediated IRF7 activation";"TRAF3-dependent IRF activation pathway";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Negative regulators of DDX58/IFIH1 signaling"
LHES000491-PA	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
LHES011184-PA	8	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;Reactome: R-HSA-5173105;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083629;MetaCyc: PWY-7922;Reactome: R-HSA-5083633	"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"O-linked glycosylation";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
LHES012882-PA	1	Reactome: R-HSA-196757	"Metabolism of folate and pterines"
LHES009267-PA	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
LHES016101-PA	56	Reactome: R-HSA-5687128;Reactome: R-HSA-5607761;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-187577;Reactome: R-HSA-8939236;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-68827;Reactome: R-HSA-8941858;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-5362768;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-5632684;Reactome: R-HSA-350562	"MAPK6/MAPK4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"SCF(Skp2)-mediated degradation of p27/p21";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"ER-Phagosome pathway";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"ABC-family proteins mediated transport";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Degradation of AXIN";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX3 expression and activity";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)"
LHES000305-PA	2	KEGG: 00900+2.7.7.60;MetaCyc: PWY-7560	"Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II"
LHES002815-PA	18	Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-166208;Reactome: R-HSA-6790901;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72689	"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"mTORC1-mediated signalling";"rRNA modification in the nucleus and cytosol";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits"
LHES001565-PA	11	MetaCyc: PWY-6174;MetaCyc: PWY-7524;MetaCyc: PWY-7560;MetaCyc: PWY-922;Reactome: R-HSA-191273;MetaCyc: PWY-6383;MetaCyc: PWY-6859;KEGG: 00900+5.3.3.2;MetaCyc: PWY-5123;MetaCyc: PWY-7102;MetaCyc: PWY-7391	"Mevalonate pathway II (archaea)";"Mevalonate pathway III (archaea)";"Methylerythritol phosphate pathway II";"Mevalonate pathway I";"Cholesterol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis";"Terpenoid backbone biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"Isoprene biosynthesis II (engineered)"
LHES006948-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
LHES010891-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
LHES007009-PA	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
LHES010052-PA	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
LHES005806-PA	4	KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2	"Lysine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism"
LHES000236-PA	5	Reactome: R-HSA-5675221;Reactome: R-HSA-112409;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"Negative regulation of MAPK pathway";"RAF-independent MAPK1/3 activation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
LHES008365-PA	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
LHES003487-PA	5	KEGG: 00240+3.6.1.6;MetaCyc: PWY-7210;KEGG: 00230+3.6.1.6;Reactome: R-HSA-6798695;MetaCyc: PWY-7185	"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Neutrophil degranulation";"UTP and CTP dephosphorylation I"
LHES007407-PA	4	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes"
LHES005476-PA	10	MetaCyc: PWY-6901;KEGG: 00010+2.7.2.3;Reactome: R-HSA-70171;KEGG: 00710+2.7.2.3;MetaCyc: PWY-8004;MetaCyc: PWY-6886;Reactome: R-HSA-70263;MetaCyc: PWY-7003;MetaCyc: PWY-5484;MetaCyc: PWY-1042	"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis";"Glycerol degradation to butanol";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)"
LHES006263-PA	7	Reactome: R-HSA-5173105;Reactome: R-HSA-5083628;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-9010553;Reactome: R-HSA-5083629	"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Regulation of expression of SLITs and ROBOs";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2"
LHES013514-PA	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
LHES001706-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES016898-PA	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
LHES009291-PA	10	MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-4041;MetaCyc: PWY-7559;MetaCyc: PWY-4061;MetaCyc: PWY-5826;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13	"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Glutathione metabolism"
LHES010450-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
LHES004330-PA	7	Reactome: R-HSA-177929;Reactome: R-HSA-2644606;Reactome: R-HSA-1442490;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948	"Signaling by EGFR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus"
LHES000438-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
LHES001214-PA	3	MetaCyc: PWY-7803;MetaCyc: PWY-6689;Reactome: R-HSA-6784531	"Trna splicing II";"Trna splicing I";"tRNA processing in the nucleus"
LHES006984-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
LHES004225-PA	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
LHES010706-PA	1	KEGG: 00982+1.14.13.8	"Drug metabolism - cytochrome P450"
LHES009935-PA	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
LHES005800-PA	16	Reactome: R-HSA-1433557;Reactome: R-HSA-389357;Reactome: R-HSA-6811558;Reactome: R-HSA-114604;Reactome: R-HSA-512988;Reactome: R-HSA-194840;Reactome: R-HSA-912631;Reactome: R-HSA-1266695;Reactome: R-HSA-9009391;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-1660499;Reactome: R-HSA-8853659;Reactome: R-HSA-912526;Reactome: R-HSA-416476;Reactome: R-HSA-388841	"Signaling by SCF-KIT";"CD28 dependent PI3K/Akt signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"GPVI-mediated activation cascade";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Rho GTPase cycle";"Regulation of signaling by CBL";"Interleukin-7 signaling";"Extra-nuclear estrogen signaling";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Synthesis of PIPs at the plasma membrane";"RET signaling";"Interleukin receptor SHC signaling";"G alpha (q) signalling events";"Costimulation by the CD28 family"
LHES005934-PA	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
LHES003594-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES011744-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
LHES004826-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
LHES005836-PA	2	KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9	"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis"
LHES002650-PA	3	Reactome: R-HSA-159230;Reactome: R-HSA-73856;Reactome: R-HSA-77588	"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
LHES004931-PA	4	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"ECM proteoglycans"
LHES005652-PA	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
LHES006241-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
LHES006867-PA	14	MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7724;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7035	"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis"
LHES015571-PA	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
LHES014476-PA	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
LHES003282-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
LHES004433-PA	1	Reactome: R-HSA-3295583	"TRP channels"
LHES009555-PA	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
LHES002759-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
LHES002383-PA	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
LHES000239-PA	2	MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24	"Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis"
LHES013576-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
LHES009775-PA	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
LHES012586-PA	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
LHES003239-PA	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
LHES009637-PA	1	Reactome: R-HSA-379716	"Cytosolic tRNA aminoacylation"
LHES014952-PA	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
LHES010921-PA	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
LHES003387-PA	3	MetaCyc: PWY-8099;MetaCyc: PWY-7158;KEGG: 00790+4.2.1.96	"Tetrahydropteridine recycling";"L-phenylalanine degradation V";"Folate biosynthesis"
LHES003273-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
LHES005168-PA	4	Reactome: R-HSA-3304356;Reactome: R-HSA-3656532;Reactome: R-HSA-2173788;Reactome: R-HSA-2173789	"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs"
LHES016638-PA	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
LHES011197-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
LHES005104-PA	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
LHES006788-PA	3	Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (i) signalling events";"G alpha (q) signalling events";"Peptide ligand-binding receptors"
LHES000960-PA	2	Reactome: R-HSA-3322077;Reactome: R-HSA-3878781	"Glycogen synthesis";"Glycogen storage disease type IV (GBE1)"
LHES010312-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
LHES001265-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
LHES006766-PA	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
LHES016945-PA	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
LHES013347-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
LHES013130-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
LHES016569-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
LHES002458-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES009111-PA	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
LHES013041-PA	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
LHES008708-PA	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
LHES007634-PA	1	Reactome: R-HSA-611105	"Respiratory electron transport"
LHES015678-PA	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
LHES002959-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
LHES008913-PA	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
LHES004204-PA	9	MetaCyc: PWY-5744;MetaCyc: PWY-241;MetaCyc: PWY-5789;MetaCyc: PWY-6142;MetaCyc: PWY-7115;Reactome: R-HSA-1475029;MetaCyc: PWY-7117;MetaCyc: PWY-5743;KEGG: 00910+4.2.1.1	"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"Nitrogen metabolism"
LHES008964-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES008211-PA	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
LHES014312-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
LHES009102-PA	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
LHES010851-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
LHES003030-PA	1	Reactome: R-HSA-176974	"Unwinding of DNA"
LHES010411-PA	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
LHES003216-PA	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
LHES007424-PA	7	KEGG: 00240+6.3.5.5;MetaCyc: PWY-5686;MetaCyc: PWY-5154;MetaCyc: PWY-7790;KEGG: 00250+6.3.5.5;MetaCyc: PWY-7791;MetaCyc: PWY-7400	"Pyrimidine metabolism";"UMP biosynthesis I";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"UMP biosynthesis II";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis III";"L-arginine biosynthesis IV (archaebacteria)"
LHES014211-PA	4	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-2161541;Reactome: R-HSA-499943	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates"
LHES008168-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
LHES006611-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
LHES006015-PA	1	Reactome: R-HSA-975578	"Reactions specific to the complex N-glycan synthesis pathway"
LHES006822-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
LHES004336-PA	8	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Signaling by Hippo";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
LHES015811-PA	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
LHES011550-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
LHES016310-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
LHES001519-PA	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8854214	"RAB geranylgeranylation";"TBC/RABGAPs"
LHES013603-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
LHES002582-PA	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
LHES008506-PA	52	Reactome: R-HSA-167160;Reactome: R-HSA-167238;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-72203;Reactome: R-HSA-5601884;Reactome: R-HSA-73863;Reactome: R-HSA-72163;Reactome: R-HSA-427413;Reactome: R-HSA-167158;Reactome: R-HSA-76061;Reactome: R-HSA-6803529;Reactome: R-HSA-167287;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-113418;Reactome: R-HSA-76071;Reactome: R-HSA-6781827;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-5578749;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-5617472;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-73980;Reactome: R-HSA-73779;Reactome: R-HSA-8851708;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-72165;Reactome: R-HSA-749476;Reactome: R-HSA-75953;Reactome: R-HSA-1834949;Reactome: R-HSA-73762;Reactome: R-HSA-203927;Reactome: R-HSA-6782210;Reactome: R-HSA-167152;Reactome: R-HSA-168325;Reactome: R-HSA-73776;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-5250924;Reactome: R-HSA-76066;Reactome: R-HSA-6782135;Reactome: R-HSA-73780;Reactome: R-HSA-77075	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Capping";"Estrogen-dependent gene expression";"Processing of Capped Intron-Containing Pre-mRNA";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase I Transcription Termination";"mRNA Splicing - Major Pathway";"NoRC negatively regulates rRNA expression";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"FGFR2 alternative splicing";"HIV elongation arrest and recovery";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"Transcriptional regulation by small RNAs";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Signaling by FGFR2 IIIa TM";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II Transcription Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase I Transcription Initiation";"MicroRNA (miRNA) biogenesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"Viral Messenger RNA Synthesis";"RNA Polymerase II Promoter Escape";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Dual incision in TC-NER";"RNA Polymerase III Chain Elongation";"RNA Pol II CTD phosphorylation and interaction with CE"
LHES007743-PA	3	Reactome: R-HSA-191859;Reactome: R-HSA-72165;Reactome: R-HSA-72163	"snRNP Assembly";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
LHES007248-PA	6	MetaCyc: PWY-7039;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system"
LHES010639-PA	1	Reactome: R-HSA-8963693	"Aspartate and asparagine metabolism"
LHES005578-PA	14	MetaCyc: PWY-7782;MetaCyc: PWY-8053;Reactome: R-HSA-1483191;MetaCyc: PWY-8051;KEGG: 00600+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8055;KEGG: 00565+3.1.3.4;Reactome: R-HSA-4419969;Reactome: R-HSA-75109;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8052;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483213	"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Synthesis of PC";"Anandamide biosynthesis I";"Sphingolipid metabolism";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Ether lipid metabolism";"Depolymerisation of the Nuclear Lamina";"Triglyceride biosynthesis";"Glycerophospholipid metabolism";"2-arachidonoylglycerol biosynthesis";"Glycerolipid metabolism";"Synthesis of PE"
LHES004122-PA	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
LHES016450-PA	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
LHES008383-PA	13	Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression"
LHES009041-PA	4	Reactome: R-HSA-163210;Reactome: R-HSA-8949613;Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"Formation of ATP by chemiosmotic coupling";"Cristae formation";"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
LHES015577-PA	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
LHES016953-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
LHES013240-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
LHES014868-PA	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
LHES002320-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
LHES008544-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
LHES013129-PA	1	Reactome: R-HSA-9640463	"Wax biosynthesis"
LHES010861-PA	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
LHES004326-PA	6	Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-427359;Reactome: R-HSA-73762;Reactome: R-HSA-73863	"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination"
LHES001277-PA	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
LHES015469-PA	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
LHES011700-PA	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
LHES005663-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
LHES016135-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES008103-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
LHES016992-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
LHES009478-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
LHES016109-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES005523-PA	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
LHES006371-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES010489-PA	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
LHES016401-PA	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
LHES004325-PA	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
LHES009990-PA	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
LHES008609-PA	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
LHES004121-PA	20	MetaCyc: PWY-7338;MetaCyc: PWY-7606;MetaCyc: PWY-7574;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-735;MetaCyc: PWY-7726;MetaCyc: PWY-7337;MetaCyc: PWY-7858;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7291;MetaCyc: PWY-7340;Reactome: R-HSA-9033241;MetaCyc: PWY-7007;KEGG: 00640+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-6837;MetaCyc: PWY-6920;KEGG: 00592+1.3.3.6	"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoyl-coa degradation II";"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(5Z)-dodecenoate biosynthesis II";"beta-Alanine metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Peroxisomal protein import";"Methyl ketone biosynthesis (engineered)";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"6-gingerol analog biosynthesis (engineered)";"alpha-Linolenic acid metabolism"
LHES007850-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
LHES016344-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
LHES009562-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
LHES003885-PA	2	Reactome: R-HSA-2514853;Reactome: R-HSA-2299718	"Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes"
LHES006851-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
LHES008744-PA	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
LHES011712-PA	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
LHES000327-PA	1	Reactome: R-HSA-5250924	"B-WICH complex positively regulates rRNA expression"
LHES010670-PA	5	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7922	"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)"
LHES011201-PA	5	Reactome: R-HSA-2132295;Reactome: R-HSA-983231;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497	"MHC class II antigen presentation";"Factors involved in megakaryocyte development and platelet production";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
LHES016504-PA	5	Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-163765	"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression"
LHES003218-PA	1	Reactome: R-HSA-191859	"snRNP Assembly"
LHES005560-PA	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
LHES005654-PA	6	Reactome: R-HSA-8874081;Reactome: R-HSA-8948216;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"MET activates PTK2 signaling";"Collagen chain trimerization";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
LHES008824-PA	5	Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
LHES010013-PA	6	Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5685938	"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)"
LHES011857-PA	14	Reactome: R-HSA-69091;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862	"Polymerase switching";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Translesion synthesis by POLK"
LHES007298-PA	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
LHES010829-PA	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
LHES003643-PA	13	Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-156827	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression"
LHES002505-PA	1	Reactome: R-HSA-211981	"Xenobiotics"
LHES013001-PA	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
LHES007739-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
LHES005579-PA	14	KEGG: 00565+3.1.3.4;KEGG: 00600+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8055;MetaCyc: PWY-8051;Reactome: R-HSA-1483191;MetaCyc: PWY-8053;MetaCyc: PWY-7782;Reactome: R-HSA-1483213;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8052;KEGG: 00564+3.1.3.4;Reactome: R-HSA-75109;Reactome: R-HSA-4419969	"Ether lipid metabolism";"Sphingolipid metabolism";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Synthesis of PC";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Synthesis of PE";"Glycerolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Glycerophospholipid metabolism";"Triglyceride biosynthesis";"Depolymerisation of the Nuclear Lamina"
LHES006061-PA	4	KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084	"Citrate cycle (TCA cycle)";"Lysine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA"
LHES002867-PA	24	Reactome: R-HSA-2871837;Reactome: R-HSA-114604;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-2730905;Reactome: R-HSA-165158;Reactome: R-HSA-9634635;Reactome: R-HSA-5674400;KEGG: 04926+2.7.11.1;Reactome: R-HSA-392451;KEGG: 05165+2.7.11.1;Reactome: R-HSA-389357;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-444257;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-6804757;Reactome: R-HSA-202424;Reactome: R-HSA-5218920;Reactome: R-HSA-5218921;Reactome: R-HSA-5607764	"FCERI mediated NF-kB activation";"GPVI-mediated activation cascade";"Human immunodeficiency virus 1 infection";"Thermogenesis";"RHO GTPases activate PKNs";"Role of LAT2/NTAL/LAB on calcium mobilization";"Activation of AKT2";"Estrogen-stimulated signaling through PRKCZ";"Constitutive Signaling by AKT1 E17K in Cancer";"Relaxin signaling pathway";"G beta:gamma signalling through PI3Kgamma";"Human papillomavirus infection";"CD28 dependent PI3K/Akt signaling";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Integrin signaling";"RSK activation";"mTOR signaling pathway";"PIP3 activates AKT signaling";"Regulation of TP53 Degradation";"Downstream TCR signaling";"VEGFR2 mediated vascular permeability";"VEGFR2 mediated cell proliferation";"CLEC7A (Dectin-1) signaling"
LHES006298-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
LHES004599-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
LHES005098-PA	1	Reactome: R-HSA-400253	"Circadian Clock"
LHES013503-PA	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
LHES002239-PA	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
LHES013888-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
LHES014649-PA	10	Reactome: R-HSA-111463;Reactome: R-HSA-5628897;Reactome: R-HSA-111459;Reactome: R-HSA-611105;Reactome: R-HSA-111464;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201;Reactome: R-HSA-9627069;Reactome: R-HSA-111457;Reactome: R-HSA-111458	"SMAC (DIABLO) binds to IAPs";"TP53 Regulates Metabolic Genes";"Activation of caspases through apoptosome-mediated cleavage";"Respiratory electron transport";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis";"Regulation of the apoptosome activity";"Release of apoptotic factors from the mitochondria";"Formation of apoptosome"
LHES002932-PA	5	Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73762	"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation"
LHES003058-PA	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
LHES014805-PA	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
LHES016079-PA	19	Reactome: R-HSA-8964041;Reactome: R-HSA-8963888;Reactome: R-HSA-8866423;Reactome: R-HSA-8856825;Reactome: R-HSA-202733;Reactome: R-HSA-5686938;Reactome: R-HSA-3000497;Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-8964046;Reactome: R-HSA-8963901;Reactome: R-HSA-8856828;Reactome: R-HSA-3000480;Reactome: R-HSA-381426;Reactome: R-HSA-3000471;Reactome: R-HSA-975634;Reactome: R-HSA-3000484;Reactome: R-HSA-8957275;Reactome: R-HSA-8964026	"LDL remodeling";"Chylomicron assembly";"VLDL assembly";"Cargo recognition for clathrin-mediated endocytosis";"Cell surface interactions at the vascular wall";"Regulation of TLR by endogenous ligand";"Scavenging by Class H Receptors";"Platelet sensitization by LDL";"LDL clearance";"VLDL clearance";"Chylomicron remodeling";"Clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class B Receptors";"Retinoid metabolism and transport";"Scavenging by Class F Receptors";"Post-translational protein phosphorylation";"Chylomicron clearance"
LHES001174-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
LHES002183-PA	5	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922	"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)"
LHES002701-PA	16	Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72649	"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Translation initiation complex formation"
LHES000586-PA	5	Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693568	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates"
LHES000170-PA	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
LHES013865-PA	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
LHES011163-PA	8	Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-190873;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900;Reactome: R-HSA-432720	"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Lysosome Vesicle Biogenesis"
LHES001210-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
LHES002240-PA	7	Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant"
LHES015035-PA	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
LHES014371-PA	4	Reactome: R-HSA-4719377;Reactome: R-HSA-4719360;Reactome: R-HSA-162699;Reactome: R-HSA-4717374	"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM1 causes DPM1-CDG (CDG-1e)"
LHES004672-PA	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
LHES006182-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
LHES003305-PA	12	KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7783;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7416;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4	"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism"
LHES002477-PA	7	Reactome: R-HSA-171306;Reactome: R-HSA-1221632;Reactome: R-HSA-110328;Reactome: R-HSA-2559586;Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-110331	"Packaging Of Telomere Ends";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine"
LHES006658-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
LHES013637-PA	20	Reactome: R-HSA-5651801;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5693607;Reactome: R-HSA-174411;Reactome: R-HSA-6804756;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121	"PCNA-Dependent Long Patch Base Excision Repair";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Translesion synthesis by POLK";"Polymerase switching";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Processing of DNA double-strand break ends";"Polymerase switching on the C-strand of the telomere";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI"
LHES000687-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
LHES015045-PA	5	Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-69205	"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"G1/S-Specific Transcription"
LHES017000-PA	2	Reactome: R-HSA-6798695;Reactome: R-HSA-2022377	"Neutrophil degranulation";"Metabolism of Angiotensinogen to Angiotensins"
LHES007802-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
LHES012286-PA	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
LHES016162-PA	5	Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-5675221;Reactome: R-HSA-5673000	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of MAPK pathway";"RAF activation"
LHES013357-PA	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
LHES004228-PA	15	Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-174048;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-176407;Reactome: R-HSA-141430;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-2467813;Reactome: R-HSA-174178	"Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
LHES001545-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
LHES016652-PA	6	Reactome: R-HSA-70221;KEGG: 00500+2.4.1.1;MetaCyc: PWY-5941;MetaCyc: PWY-7238;MetaCyc: PWY-6737;MetaCyc: PWY-6731	"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism";"Glycogen degradation II";"Sucrose biosynthesis II";"Starch degradation V";"Starch degradation III"
LHES000857-PA	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
LHES003676-PA	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214815	"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones"
LHES013818-PA	2	Reactome: R-HSA-389397;Reactome: R-HSA-416476	"Orexin and neuropeptides FF and QRFP bind to their respective receptors";"G alpha (q) signalling events"
LHES008487-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
LHES014656-PA	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
LHES003854-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
LHES009266-PA	13	Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-156827	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression"
LHES006875-PA	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
LHES000679-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
LHES006319-PA	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
LHES006218-PA	6	Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-69473	"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint"
LHES000555-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
LHES000880-PA	7	Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380284	"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
LHES005471-PA	4	MetaCyc: PWY-5704;KEGG: 00230+3.5.1.5;KEGG: 00220+3.5.1.5;KEGG: 00791+3.5.1.5	"Urea degradation II";"Purine metabolism";"Arginine biosynthesis";"Atrazine degradation"
LHES001319-PA	9	Reactome: R-HSA-3560783;Reactome: R-HSA-3560801;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-975634;Reactome: R-HSA-4420332;Reactome: R-HSA-2022928;Reactome: R-HSA-1971475	"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GAT3 causes JDSSDHD";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"Retinoid metabolism and transport";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis"
LHES009643-PA	6	MetaCyc: PWY-7382;Reactome: R-HSA-3371599;KEGG: 00780+6.3.4.15;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;Reactome: R-HSA-196780	"Lipoate biosynthesis and incorporation IV (yeast)";"Defective HLCS causes multiple carboxylase deficiency";"Biotin metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism"
LHES004679-PA	7	Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
LHES003918-PA	13	Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339	"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane"
LHES002016-PA	4	KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188;Reactome: R-HSA-379726	"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Mitochondrial tRNA aminoacylation"
LHES008014-PA	1	Reactome: R-HSA-70171	"Glycolysis"
LHES003263-PA	6	MetaCyc: PWY-6527;Reactome: R-HSA-5609978;KEGG: 00520+2.7.7.12;Reactome: R-HSA-70370;KEGG: 00052+2.7.7.12;MetaCyc: PWY-6317	"Stachyose degradation";"Defective GALT can cause Galactosemia";"Amino sugar and nucleotide sugar metabolism";"Galactose catabolism";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)"
LHES011608-PA	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
LHES006440-PA	1	Reactome: R-HSA-8951664	"Neddylation"
LHES006403-PA	6	Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7920	"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)"
LHES001350-PA	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
LHES005928-PA	4	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
LHES006517-PA	6	MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
LHES004441-PA	8	Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1	"Glycolysis";"Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Starch and sucrose metabolism"
LHES001912-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
LHES003033-PA	10	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04150+2.7.11.1;Reactome: R-HSA-442742;Reactome: R-HSA-444257	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Recycling pathway of L1";"mTOR signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"RSK activation"
LHES012732-PA	1	Reactome: R-HSA-419771	"Opsins"
LHES001887-PA	6	KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817	"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
LHES001137-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
LHES013375-PA	11	MetaCyc: PWY-6679;KEGG: 00620+6.4.1.2;KEGG: 00640+6.4.1.2;Reactome: R-HSA-2426168;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5966-1;Reactome: R-HSA-163765;KEGG: 00254+6.4.1.2;Reactome: R-HSA-196780;Reactome: R-HSA-200425;KEGG: 00061+6.4.1.2	"Jadomycin biosynthesis";"Pyruvate metabolism";"Propanoate metabolism";"Activation of gene expression by SREBF (SREBP)";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression";"Aflatoxin biosynthesis";"Biotin transport and metabolism";"Carnitine metabolism";"Fatty acid biosynthesis"
LHES006767-PA	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
LHES006676-PA	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
LHES004253-PA	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
LHES006983-PA	1	Reactome: R-HSA-74217	"Purine salvage"
LHES011947-PA	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
LHES016691-PA	5	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
LHES010028-PA	3	Reactome: R-HSA-264870;Reactome: R-HSA-6798695;Reactome: R-HSA-6794361	"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation";"Neurexins and neuroligins"
LHES008494-PA	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
LHES001662-PA	6	KEGG: 00380+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-6798695	"Tryptophan metabolism";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import";"Neutrophil degranulation"
LHES009645-PA	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
LHES011975-PA	1	Reactome: R-HSA-8951664	"Neddylation"
LHES000797-PA	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
LHES003825-PA	5	MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22	"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Sphingolipid metabolism";"Galactose metabolism"
LHES008072-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES009342-PA	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
LHES003532-PA	17	KEGG: 00230+2.7.4.6;MetaCyc: PWY-7220;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7227;MetaCyc: PWY-7222;MetaCyc: PWY-7210;MetaCyc: PWY-7221;MetaCyc: PWY-7187;MetaCyc: PWY-7184;MetaCyc: PWY-7205;MetaCyc: PWY-7197;MetaCyc: PWY-7226;MetaCyc: PWY-7176;MetaCyc: PWY-7224;MetaCyc: PWY-6545;KEGG: 00983+2.7.4.6	"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes"
LHES008224-PA	32	Reactome: R-HSA-75953;Reactome: R-HSA-72165;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-8851708;Reactome: R-HSA-73779;Reactome: R-HSA-167290;Reactome: R-HSA-73776;Reactome: R-HSA-168325;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-72203;Reactome: R-HSA-9018519;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-76042;Reactome: R-HSA-167287;Reactome: R-HSA-6803529;Reactome: R-HSA-72163;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-167172	"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of HIV elongation";"RNA Polymerase II Promoter Escape";"Viral Messenger RNA Synthesis";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"Processing of Capped Intron-Containing Pre-mRNA";"Estrogen-dependent gene expression";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV elongation arrest and recovery";"FGFR2 alternative splicing";"mRNA Splicing - Major Pathway";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription of the HIV genome"
LHES011819-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
LHES005628-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
LHES007296-PA	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
LHES007655-PA	1	Reactome: R-HSA-9640463	"Wax biosynthesis"
LHES015352-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
LHES015838-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES014757-PA	16	Reactome: R-HSA-8964038;Reactome: R-HSA-177504;Reactome: R-HSA-5140745;Reactome: R-HSA-2132295;Reactome: R-HSA-190873;Reactome: R-HSA-437239;Reactome: R-HSA-8856825;Reactome: R-HSA-416993;Reactome: R-HSA-8866427;Reactome: R-HSA-5099900;Reactome: R-HSA-167590;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-164939;Reactome: R-HSA-182218;Reactome: R-HSA-196025	"LDL clearance";"Retrograde neurotrophin signalling";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"MHC class II antigen presentation";"Gap junction degradation";"Recycling pathway of L1";"Cargo recognition for clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD4";"Nef Mediated CD4 Down-regulation";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Nef mediated downregulation of CD28 cell surface expression";"Nef Mediated CD8 Down-regulation";"Formation of annular gap junctions"
LHES000864-PA	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
LHES016604-PA	6	MetaCyc: PWY-6737;MetaCyc: PWY-7238;MetaCyc: PWY-6731;Reactome: R-HSA-70221;KEGG: 00500+2.4.1.1;MetaCyc: PWY-5941	"Starch degradation V";"Sucrose biosynthesis II";"Starch degradation III";"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism";"Glycogen degradation II"
LHES014145-PA	5	MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22	"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Sphingolipid metabolism";"Galactose metabolism"
LHES007897-PA	8	KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171	"Starch and sucrose metabolism";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Glycolysis"
LHES006330-PA	3	KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367;MetaCyc: PWY-6368	"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"3-phosphoinositide degradation"
LHES000088-PA	1	Reactome: R-HSA-6787639	"GDP-fucose biosynthesis"
LHES014398-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
LHES016221-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
LHES012950-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
LHES000677-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
LHES006908-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
LHES008112-PA	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
LHES004533-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
LHES015875-PA	5	KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5667;MetaCyc: PWY-7817;MetaCyc: PWY-5981	"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III"
LHES005357-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
LHES006569-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES000225-PA	2	Reactome: R-HSA-456926;Reactome: R-HSA-416482	"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events"
LHES008231-PA	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
LHES008209-PA	4	MetaCyc: PWY-5188;MetaCyc: PWY-5189;KEGG: 00860+2.5.1.61;Reactome: R-HSA-189451	"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
LHES009789-PA	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1"
LHES016834-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
LHES001264-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
LHES007264-PA	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
LHES002233-PA	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
LHES000484-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
LHES001187-PA	5	Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-110357;Reactome: R-HSA-9608290;Reactome: R-HSA-9608287	"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1";"Defective MUTYH substrate processing";"Defective MUTYH substrate binding"
LHES009571-PA	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
LHES008739-PA	4	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)"
LHES012348-PA	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
LHES003253-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
LHES012949-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
LHES004192-PA	9	Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695	"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events"
LHES010157-PA	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
LHES002649-PA	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
LHES001009-PA	22	Reactome: R-HSA-5675221;Reactome: R-HSA-5467340;Reactome: R-HSA-432142;Reactome: R-HSA-5358747;Reactome: R-HSA-5467337;Reactome: R-HSA-68877;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-5673000;Reactome: R-HSA-141444;Reactome: R-HSA-195253;Reactome: R-HSA-5358749;Reactome: R-HSA-2467813;Reactome: R-HSA-389513;Reactome: R-HSA-5467348;Reactome: R-HSA-6811558;Reactome: R-HSA-9648025;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-5663220;Reactome: R-HSA-5358751;Reactome: R-HSA-196299	"Negative regulation of MAPK pathway";"AXIN missense mutants destabilize the destruction complex";"Platelet sensitization by LDL";"S33 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Mitotic Prometaphase";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"RAF activation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Degradation of beta-catenin by the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"CTLA4 inhibitory signaling";"Truncations of AMER1 destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"EML4 and NUDC in mitotic spindle formation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"RHO GTPases Activate Formins";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade"
LHES012558-PA	10	MetaCyc: PWY-5340;Reactome: R-HSA-2408550;MetaCyc: PWY-5278;Reactome: R-HSA-174362;MetaCyc: PWY-6932;KEGG: 00920+2.7.7.4;KEGG: 00450+2.7.7.4;KEGG: 00230+2.7.7.4;MetaCyc: PWY-6683;KEGG: 00261+2.7.7.4	"Sulfate activation for sulfonation";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfite oxidation III";"Transport and synthesis of PAPS";"Selenate reduction";"Sulfur metabolism";"Selenocompound metabolism";"Purine metabolism";"Assimilatory sulfate reduction III";"Monobactam biosynthesis"
LHES006409-PA	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
LHES015741-PA	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
LHES003088-PA	8	MetaCyc: PWY-7184;MetaCyc: PWY-7187;MetaCyc: PWY-6545;MetaCyc: PWY-7210;KEGG: 00240+2.7.4.9;Reactome: R-HSA-499943;MetaCyc: PWY-7198;MetaCyc: PWY-7197	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation"
LHES016790-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
LHES002123-PA	26	Reactome: R-HSA-9013508;Reactome: R-HSA-5617472;Reactome: R-HSA-1234158;Reactome: R-HSA-8866907;Reactome: R-HSA-3371568;Reactome: R-HSA-9013695;Reactome: R-HSA-3899300;Reactome: R-HSA-201722;Reactome: R-HSA-918233;Reactome: R-HSA-210744;Reactome: R-HSA-2644606;Reactome: R-HSA-1989781;Reactome: R-HSA-3214847;Reactome: R-HSA-3134973;Reactome: R-HSA-933541;Reactome: R-HSA-1912408;Reactome: R-HSA-400253;Reactome: R-HSA-2894862;Reactome: R-HSA-9614657;Reactome: R-HSA-8941856;Reactome: R-HSA-5621575;Reactome: R-HSA-381340;Reactome: R-HSA-9617629;Reactome: R-HSA-9018519;Reactome: R-HSA-2122947;Reactome: R-HSA-1368082	"NOTCH3 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression by Hypoxia-inducible Factor";"Activation of the TFAP2 (AP-2) family of transcription factors";"Attenuation phase";"NOTCH4 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"Formation of the beta-catenin:TCF transactivating complex";"TRAF3-dependent IRF activation pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"PPARA activates gene expression";"HATs acetylate histones";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"TRAF6 mediated IRF7 activation";"Pre-NOTCH Transcription and Translation";"Circadian Clock";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"FOXO-mediated transcription of cell death genes";"RUNX3 regulates NOTCH signaling";"CD209 (DC-SIGN) signaling";"Transcriptional regulation of white adipocyte differentiation";"Regulation of FOXO transcriptional activity by acetylation";"Estrogen-dependent gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"RORA activates gene expression"
LHES013293-PA	3	KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857;Reactome: R-HSA-192456	"Glycerolipid metabolism";"Retinol biosynthesis";"Digestion of dietary lipid"
LHES009809-PA	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
LHES001341-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
LHES005130-PA	5	Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-2132295	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"MHC class II antigen presentation"
LHES012725-PA	22	MetaCyc: PWY-7724;MetaCyc: PWY-7727;MetaCyc: PWY-7053;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-5353;KEGG: 00062+4.2.1.134;MetaCyc: PWY-6433;MetaCyc: PWY-7726;MetaCyc: PWY-7036;MetaCyc: PWY-7592;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7606;MetaCyc: PWY-7049;MetaCyc: PWY-6598;MetaCyc: PWY-7728;MetaCyc: PWY-6958;MetaCyc: PWY-8041	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Sciadonate biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis"
LHES013892-PA	1	Reactome: R-HSA-419771	"Opsins"
LHES001024-PA	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
LHES013651-PA	26	Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-389960;Reactome: R-HSA-8955332;Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-190861;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-389977;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-9609690	"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"Formation of tubulin folding intermediates by CCT/TriC";"Carboxyterminal post-translational modifications of tubulin";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"Gap junction assembly";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"Post-chaperonin tubulin folding pathway";"MHC class II antigen presentation";"Kinesins";"HCMV Early Events"
LHES016547-PA	2	Reactome: R-HSA-392154;Reactome: R-HSA-1222556	"Nitric oxide stimulates guanylate cyclase";"ROS and RNS production in phagocytes"
LHES006334-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
LHES016669-PA	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
LHES006747-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
LHES017141-PA	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
LHES004805-PA	1	Reactome: R-HSA-73621	"Pyrimidine catabolism"
LHES005191-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
LHES001259-PA	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
LHES000190-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
LHES014966-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
LHES010622-PA	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
LHES016218-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
LHES000554-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
LHES001840-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
LHES010171-PA	13	MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7198;KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-6545;KEGG: 00480+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7220;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1	"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Glutathione metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism"
LHES007026-PA	1	KEGG: 00982+1.14.13.8	"Drug metabolism - cytochrome P450"
LHES004789-PA	4	Reactome: R-HSA-983231;Reactome: R-HSA-982772;Reactome: R-HSA-2586552;Reactome: R-HSA-1170546	"Factors involved in megakaryocyte development and platelet production";"Growth hormone receptor signaling";"Signaling by Leptin";"Prolactin receptor signaling"
LHES012826-PA	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
LHES013523-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
LHES006654-PA	5	KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22	"Galactose metabolism";"Sphingolipid metabolism";"Glycerolipid metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series"
LHES013644-PA	2	Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2	"Glycine degradation";"Glycine, serine and threonine metabolism"
LHES000314-PA	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
LHES015251-PA	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
LHES001012-PA	1	Reactome: R-HSA-8951664	"Neddylation"
LHES015223-PA	8	KEGG: 00190+7.1.2.2;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-9639288	"Oxidative phosphorylation";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Photosynthesis";"ATP biosynthesis";"Amino acids regulate mTORC1"
LHES010916-PA	4	Reactome: R-HSA-1660662;MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119	"Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)"
LHES013554-PA	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
LHES011450-PA	14	KEGG: 00460+2.1.2.1;MetaCyc: PWY-181;MetaCyc: PWY-2201;MetaCyc: PWY-5497;MetaCyc: PWY-1622;Reactome: R-HSA-196757;KEGG: 00680+2.1.2.1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-3841;KEGG: 00260+2.1.2.1;MetaCyc: PWY-3661-1;MetaCyc: PWY-2161;KEGG: 00630+2.1.2.1;MetaCyc: PWY-3661	"Cyanoamino acid metabolism";"Photorespiration ";"Folate transformations I";"Purine nucleobases degradation II (anaerobic)";"Formaldehyde assimilation I (serine pathway)";"Metabolism of folate and pterines";"Methane metabolism";"One carbon pool by folate";"Folate transformations II (plants)";"Glycine, serine and threonine metabolism";"Glycine betaine degradation II (mammalian)";"Folate polyglutamylation";"Glyoxylate and dicarboxylate metabolism";"Glycine betaine degradation I"
LHES007484-PA	1	Reactome: R-HSA-8964572	"Lipid particle organization"
LHES009659-PA	5	Reactome: R-HSA-5632684;Reactome: R-HSA-373080;Reactome: R-HSA-5635838;Reactome: R-HSA-5610787;Reactome: R-HSA-5620922	"Hedgehog 'on' state";"Class B/2 (Secretin family receptors)";"Activation of SMO";"Hedgehog 'off' state";"BBSome-mediated cargo-targeting to cilium"
LHES005871-PA	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
LHES004549-PA	6	Reactome: R-HSA-381426;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-8957275;Reactome: R-HSA-381038;Reactome: R-HSA-6798695	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Post-translational protein phosphorylation";"XBP1(S) activates chaperone genes";"Neutrophil degranulation"
LHES000272-PA	4	Reactome: R-HSA-5334118;Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427	"DNA methylation";"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins"
LHES000446-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
LHES003552-PA	5	Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565	"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
LHES003311-PA	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
LHES000007-PA	6	Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-264642	"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle"
LHES006493-PA	27	Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854	"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly"
LHES011379-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES014777-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
LHES007684-PA	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
LHES016322-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
LHES014426-PA	12	Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-6804756;Reactome: R-HSA-75955;Reactome: R-HSA-167238	"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation"
LHES010881-PA	5	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-6784531	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"tRNA processing in the nucleus"
LHES010899-PA	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
LHES008245-PA	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
LHES011661-PA	2	Reactome: R-HSA-1222556;Reactome: R-HSA-392154	"ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase"
LHES001197-PA	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
LHES010919-PA	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
LHES003711-PA	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
LHES010440-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
LHES000363-PA	10	KEGG: 00052+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-7385;KEGG: 00051+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11	"Galactose metabolism";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway"
LHES003249-PA	57	Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-6798695;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-187577;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-69017;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-5687128;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-5676590	"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"ABC-family proteins mediated transport";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Neutrophil degranulation";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"SCF(Skp2)-mediated degradation of p27/p21";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"MAPK6/MAPK4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling"
LHES010759-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
LHES014074-PA	14	MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-8041	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis"
LHES009239-PA	7	Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288	"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1"
LHES014392-PA	3	Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I"
LHES010717-PA	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
LHES000368-PA	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
LHES016175-PA	1	Reactome: R-HSA-70921	"Histidine catabolism"
LHES013814-PA	1	Reactome: R-HSA-525793	"Myogenesis"
LHES000023-PA	1	Reactome: R-HSA-1483166	"Synthesis of PA"
LHES009785-PA	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
LHES007907-PA	5	Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-983170	"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
LHES011935-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
LHES007906-PA	5	Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-204005	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"COPII-mediated vesicle transport"
LHES010107-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
LHES010330-PA	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway"
LHES015098-PA	1	Reactome: R-HSA-8951664	"Neddylation"
LHES016847-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES004058-PA	8	Reactome: R-HSA-975957;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway"
LHES000448-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
LHES008035-PA	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
LHES011846-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
LHES006335-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
LHES002664-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
LHES001693-PA	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
LHES006482-PA	42	KEGG: 00623+1.1.1.35;MetaCyc: PWY-6435;MetaCyc: PWY-5109;MetaCyc: PWY-6945;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;MetaCyc: PWY-5177;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;MetaCyc: PWY-6863;KEGG: 00592+4.2.1.17;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7656;MetaCyc: PWY-6583;KEGG: 00640+4.2.1.17;MetaCyc: PWY-5136;MetaCyc: PWY-7401;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7779;MetaCyc: PWY-6944;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;MetaCyc: PWY-7606;MetaCyc: PWY-7778;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;MetaCyc: PWY-5138;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;MetaCyc: PWY-7007;KEGG: 00410+4.2.1.17	"Toluene degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Fermentation to 2-methylbutanoate";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fatty acid degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Glutaryl-coa degradation";"Fatty acid degradation";"Benzoate degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Pyruvate fermentation to hexanol (engineered)";"alpha-Linolenic acid metabolism";"Aminobenzoate degradation";"Spodoptera littoralis pheromone biosynthesis";"Pyruvate fermentation to butanol I";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Geraniol degradation";"Pyruvate fermentation to butanol II (engineered)";"Phenylalanine metabolism";"Methyl tert-butyl ether degradation";"Androstenedione degradation";"Tryptophan metabolism";"Butanoate metabolism";"Fatty acid elongation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"2-methylpropene degradation";"Caprolactam degradation";"Limonene and pinene degradation";"Valine, leucine and isoleucine degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Carbon fixation pathways in prokaryotes";"Fatty acid salvage";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Lysine degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Butanoate metabolism";"Benzoyl-coa degradation I (aerobic)";"Methyl ketone biosynthesis (engineered)";"beta-Alanine metabolism"
LHES002832-PA	12	KEGG: 00720+6.4.1.3;KEGG: 00630+6.4.1.3;MetaCyc: PWY-5743;KEGG: 00280+6.4.1.3;MetaCyc: PWY-6728;MetaCyc: PWYG-321;Reactome: R-HSA-3371599;KEGG: 00640+6.4.1.3;Reactome: R-HSA-71032;Reactome: R-HSA-196780;MetaCyc: PWY-7384;MetaCyc: PWY-5789	"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"3-hydroxypropanoate cycle";"Valine, leucine and isoleucine degradation";"Methylaspartate cycle";"";"Defective HLCS causes multiple carboxylase deficiency";"Propanoate metabolism";"Propionyl-CoA catabolism";"Biotin transport and metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"3-hydroxypropanoate/4-hydroxybutanate cycle"
LHES008983-PA	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
LHES002216-PA	4	Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-69205	"Activation of ATR in response to replication stress";"Unwinding of DNA";"Activation of the pre-replicative complex";"G1/S-Specific Transcription"
LHES015582-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
LHES004603-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
LHES002735-PA	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
LHES003559-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
LHES013443-PA	3	Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
LHES001456-PA	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1"
LHES014911-PA	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578998	"Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)"
LHES006549-PA	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847	"DNA Damage Recognition in GG-NER";"UCH proteinases";"HATs acetylate histones"
LHES016799-PA	1	Reactome: R-HSA-8951664	"Neddylation"
LHES013543-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
LHES010570-PA	11	Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-432040	"PKA activation";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins"
LHES010952-PA	4	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation";"RHO GTPases activate KTN1"
LHES010178-PA	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
LHES002636-PA	2	Reactome: R-HSA-1433559;Reactome: R-HSA-8951664	"Regulation of KIT signaling";"Neddylation"
LHES015415-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
LHES003657-PA	1	Reactome: R-HSA-8951664	"Neddylation"
LHES016809-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
LHES003564-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
LHES006184-PA	2	Reactome: R-HSA-532668;Reactome: R-HSA-6798695	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation"
LHES002938-PA	26	Reactome: R-HSA-8866907;Reactome: R-HSA-3371568;Reactome: R-HSA-9013508;Reactome: R-HSA-5617472;Reactome: R-HSA-1234158;Reactome: R-HSA-3899300;Reactome: R-HSA-201722;Reactome: R-HSA-918233;Reactome: R-HSA-9013695;Reactome: R-HSA-3134973;Reactome: R-HSA-933541;Reactome: R-HSA-1912408;Reactome: R-HSA-2894862;Reactome: R-HSA-400253;Reactome: R-HSA-210744;Reactome: R-HSA-2644606;Reactome: R-HSA-1989781;Reactome: R-HSA-3214847;Reactome: R-HSA-381340;Reactome: R-HSA-9617629;Reactome: R-HSA-2122947;Reactome: R-HSA-9018519;Reactome: R-HSA-1368082;Reactome: R-HSA-9614657;Reactome: R-HSA-8941856;Reactome: R-HSA-5621575	"Activation of the TFAP2 (AP-2) family of transcription factors";"Attenuation phase";"NOTCH3 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression by Hypoxia-inducible Factor";"SUMOylation of transcription cofactors";"Formation of the beta-catenin:TCF transactivating complex";"TRAF3-dependent IRF activation pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"TRAF6 mediated IRF7 activation";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Circadian Clock";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"PPARA activates gene expression";"HATs acetylate histones";"Transcriptional regulation of white adipocyte differentiation";"Regulation of FOXO transcriptional activity by acetylation";"NOTCH1 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"RORA activates gene expression";"FOXO-mediated transcription of cell death genes";"RUNX3 regulates NOTCH signaling";"CD209 (DC-SIGN) signaling"
LHES000238-PA	7	MetaCyc: PWY-5265;Reactome: R-HSA-446193;MetaCyc: PWY-6471;KEGG: 00510+2.7.8.15;KEGG: 00550+2.7.8.13;Reactome: R-HSA-4549356;MetaCyc: PWY-6470	"Peptidoglycan biosynthesis II (staphylococci)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis V (beta-lactam resistance)"
LHES008346-PA	16	Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-141430	"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Inactivation of APC/C via direct inhibition of the APC/C complex"
LHES003783-PA	1	Reactome: R-HSA-8963693	"Aspartate and asparagine metabolism"
LHES002645-PA	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
LHES011068-PA	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
LHES003074-PA	27	Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-165054	"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA"
LHES004664-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES001976-PA	10	MetaCyc: PWY-7210;MetaCyc: PWY-7199;Reactome: R-HSA-69205;Reactome: R-HSA-499943;MetaCyc: PWY-7198;MetaCyc: PWY-3841;KEGG: 00240+2.1.1.45;KEGG: 00670+2.1.1.45;MetaCyc: PWY-7184;MetaCyc: PWY-7187	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleosides salvage";"G1/S-Specific Transcription";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Folate transformations II (plants)";"Pyrimidine metabolism";"One carbon pool by folate";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
LHES004235-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
LHES008119-PA	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
LHES005159-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
LHES008998-PA	4	Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
LHES013046-PA	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
LHES008282-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
LHES003524-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
LHES008912-PA	1	Reactome: R-HSA-70921	"Histidine catabolism"
LHES004761-PA	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
LHES016593-PA	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
LHES006252-PA	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
LHES008578-PA	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
LHES004616-PA	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
LHES005103-PA	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
LHES002628-PA	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
LHES000847-PA	5	Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-163765;Reactome: R-HSA-75105;Reactome: R-HSA-2426168	"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)"
LHES006229-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
LHES013057-PA	1	Reactome: R-HSA-977347	"Serine biosynthesis"
LHES015219-PA	2	Reactome: R-HSA-8949215;Reactome: R-HSA-5689880	"Mitochondrial calcium ion transport";"Ub-specific processing proteases"
LHES007589-PA	5	KEGG: 00020+4.1.1.32;Reactome: R-HSA-70263;KEGG: 00010+4.1.1.32;KEGG: 00620+4.1.1.32;MetaCyc: PWY-7383	"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)"
LHES001011-PA	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
LHES003352-PA	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
LHES011212-PA	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
LHES009745-PA	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
LHES008486-PA	30	Reactome: R-HSA-77075;Reactome: R-HSA-2564830;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-167152;Reactome: R-HSA-6781827;Reactome: R-HSA-75955;Reactome: R-HSA-5696400;Reactome: R-HSA-76042;Reactome: R-HSA-113418;Reactome: R-HSA-73762;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-73779;Reactome: R-HSA-5696395;Reactome: R-HSA-167160	"RNA Pol II CTD phosphorylation and interaction with CE";"Cytosolic iron-sulfur cluster assembly";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Elongation";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
LHES006132-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
LHES009191-PA	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
LHES011754-PA	3	Reactome: R-HSA-1660662;KEGG: 00600+3.1.4.12;MetaCyc: PWY-7277	"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Sphingolipid biosynthesis (mammals)"
LHES010246-PA	7	Reactome: R-HSA-373080;Reactome: R-HSA-5632684;Reactome: R-HSA-5632681;Reactome: R-HSA-5658034;Reactome: R-HSA-5358346;Reactome: R-HSA-5635838;Reactome: R-HSA-5362798	"Class B/2 (Secretin family receptors)";"Hedgehog 'on' state";"Ligand-receptor interactions";"HHAT G278V abrogates palmitoylation of Hh-Np";"Hedgehog ligand biogenesis";"Activation of SMO";"Release of Hh-Np from the secreting cell"
LHES006216-PA	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Neutrophil degranulation"
LHES008004-PA	13	Reactome: R-HSA-2243919;Reactome: R-HSA-1474244;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-2214320;Reactome: R-HSA-3000157;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-3000178;Reactome: R-HSA-419037;Reactome: R-HSA-186797;Reactome: R-HSA-216083	"Crosslinking of collagen fibrils";"Extracellular matrix organization";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Anchoring fibril formation";"Laminin interactions";"Collagen chain trimerization";"Collagen degradation";"ECM proteoglycans";"NCAM1 interactions";"Signaling by PDGF";"Integrin cell surface interactions"
LHES013015-PA	1	Reactome: R-HSA-8949613	"Cristae formation"
LHES005166-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
LHES010655-PA	5	MetaCyc: PWY-6123;KEGG: 00230+6.3.2.6;MetaCyc: PWY-7234;MetaCyc: PWY-6124;Reactome: R-HSA-73817	"Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis"
LHES002218-PA	5	Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-5674400;Reactome: R-HSA-165159;Reactome: R-HSA-198323	"HSF1-dependent transactivation";"mTORC1-mediated signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signalling";"AKT phosphorylates targets in the cytosol"
LHES004674-PA	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
LHES017182-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
LHES004269-PA	1	Reactome: R-HSA-3295583	"TRP channels"
LHES008334-PA	8	KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171	"Starch and sucrose metabolism";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Glycolysis"
LHES006418-PA	5	KEGG: 00860+4.2.1.24;MetaCyc: PWY-5188;MetaCyc: PWY-5189;Reactome: R-HSA-6798695;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Neutrophil degranulation";"Heme biosynthesis"
LHES015227-PA	14	Reactome: R-HSA-450520;Reactome: R-HSA-141444;Reactome: R-HSA-69273;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9634638;Reactome: R-HSA-2173788;Reactome: R-HSA-168333;Reactome: R-HSA-68877;Reactome: R-HSA-5687128;Reactome: R-HSA-9648025;Reactome: R-HSA-3769402;Reactome: R-HSA-165054;Reactome: R-HSA-2500257	"HuR (ELAVL1) binds and stabilizes mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Cyclin A/B1/B2 associated events during G2/M transition";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Downregulation of TGF-beta receptor signaling";"NEP/NS2 Interacts with the Cellular Export Machinery";"Mitotic Prometaphase";"MAPK6/MAPK4 signaling";"EML4 and NUDC in mitotic spindle formation";"Deactivation of the beta-catenin transactivating complex";"Rev-mediated nuclear export of HIV RNA";"Resolution of Sister Chromatid Cohesion"
LHES010386-PA	17	Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-174414;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-174437;Reactome: R-HSA-5358606;Reactome: R-HSA-174417;Reactome: R-HSA-5651801;Reactome: R-HSA-5358565	"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the C-strand of the telomere";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Telomere C-strand (Lagging Strand) Synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
LHES008954-PA	9	Reactome: R-HSA-68962;Reactome: R-HSA-1362277;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-69205;Reactome: R-HSA-68949;Reactome: R-HSA-69017	"Activation of the pre-replicative complex";"Transcription of E2F targets under negative control by DREAM complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"G1/S-Specific Transcription";"Orc1 removal from chromatin";"CDK-mediated phosphorylation and removal of Cdc6"
LHES009578-PA	5	Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-5625740	"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs"
LHES001342-PA	7	Reactome: R-HSA-389661;KEGG: 00020+2.3.1.61;KEGG: 00310+2.3.1.61;KEGG: 00380+2.3.1.61;Reactome: R-HSA-71064;MetaCyc: PWY-5084;Reactome: R-HSA-71403	"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"Tryptophan metabolism";"Lysine catabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citric acid cycle (TCA cycle)"
LHES004481-PA	6	Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68867	"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex"
LHES012069-PA	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
LHES013453-PA	3	Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)"
LHES008513-PA	11	Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-163615	"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"PKA activation"
LHES010650-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
LHES013091-PA	8	Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-6804115;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition"
LHES017110-PA	7	MetaCyc: PWY-7841;KEGG: 00600+2.4.1.80;Reactome: R-HSA-1660662;MetaCyc: PWY-7836;MetaCyc: PWY-5129;MetaCyc: PWY-7839;MetaCyc: PWY-7838	"Neolacto-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ganglio-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Lacto-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis"
LHES000353-PA	5	Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;KEGG: 00230+2.7.4.10	"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism";"Purine metabolism"
LHES003471-PA	9	Reactome: R-HSA-1971475;Reactome: R-HSA-2022928;Reactome: R-HSA-4420332;Reactome: R-HSA-975634;Reactome: R-HSA-2024096;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801;Reactome: R-HSA-3560783	"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG biosynthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Retinoid metabolism and transport";"HS-GAG degradation";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type"
LHES004485-PA	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
LHES002913-PA	5	Reactome: R-HSA-1482922;Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;Reactome: R-HSA-1483115;Reactome: R-HSA-1482839	"Acyl chain remodelling of PI";"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Hydrolysis of LPC";"Acyl chain remodelling of PE"
LHES004242-PA	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
LHES000394-PA	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
LHES001863-PA	3	Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118	"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors"
LHES012041-PA	8	KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1	"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Galactose metabolism"
LHES000207-PA	4	Reactome: R-HSA-389661;MetaCyc: PWY-7382;KEGG: 00785+2.8.1.8;MetaCyc: PWY-6987	"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)"
LHES004737-PA	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
LHES004271-PA	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
LHES001278-PA	3	Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2024096	"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation";"HS-GAG degradation"
LHES006516-PA	5	Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-163765	"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression"
LHES015946-PA	6	Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
LHES001050-PA	12	MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Arachidonic acid metabolism"
LHES015910-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
LHES004178-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
LHES008080-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES015735-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
LHES009215-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
LHES006428-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
LHES016113-PA	3	KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980	"Oxidative phosphorylation";"Photosynthesis";"ATP biosynthesis"
LHES004161-PA	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
LHES011697-PA	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
LHES005865-PA	14	MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7601	"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
LHES008781-PA	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
LHES014353-PA	1	Reactome: R-HSA-977347	"Serine biosynthesis"
LHES005327-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
LHES011044-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
LHES014709-PA	6	Reactome: R-HSA-6798695;Reactome: R-HSA-9033241;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;KEGG: 00380+1.11.1.6	"Neutrophil degranulation";"Peroxisomal protein import";"Glyoxylate and dicarboxylate metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Tryptophan metabolism"
LHES005077-PA	5	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5675221;Reactome: R-HSA-112409;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Negative regulation of MAPK pathway";"RAF-independent MAPK1/3 activation";"Th1 and Th2 cell differentiation"
LHES005576-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
LHES015548-PA	5	Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-983170	"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
LHES012307-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
LHES004477-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
LHES012187-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
LHES004810-PA	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
LHES003698-PA	6	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
LHES010763-PA	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
LHES009682-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
LHES012622-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
LHES003557-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
LHES009609-PA	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2024101;Reactome: R-HSA-2206302	"HS-GAG degradation";"CS/DS degradation";"MPS I - Hurler syndrome"
LHES010259-PA	1	Reactome: R-HSA-8951664	"Neddylation"
LHES006101-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
LHES009837-PA	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
LHES002068-PA	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
LHES011794-PA	3	Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942	"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)"
LHES004855-PA	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
LHES013909-PA	13	Reactome: R-HSA-3928665;Reactome: R-HSA-2132295;Reactome: R-HSA-5140745;Reactome: R-HSA-8856828;Reactome: R-HSA-177504;Reactome: R-HSA-8856825;Reactome: R-HSA-182218;Reactome: R-HSA-437239;Reactome: R-HSA-8866427;Reactome: R-HSA-8964038;Reactome: R-HSA-416993;Reactome: R-HSA-167590;Reactome: R-HSA-5099900	"EPH-ephrin mediated repulsion of cells";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Clathrin-mediated endocytosis";"Retrograde neurotrophin signalling";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD8 Down-regulation";"Recycling pathway of L1";"VLDLR internalisation and degradation";"LDL clearance";"Trafficking of GluR2-containing AMPA receptors";"Nef Mediated CD4 Down-regulation";"WNT5A-dependent internalization of FZD4"
LHES007834-PA	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
LHES014267-PA	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
LHES003566-PA	7	Reactome: R-HSA-5689880;Reactome: R-HSA-6804756;Reactome: R-HSA-6804757;Reactome: R-HSA-6804760;Reactome: R-HSA-69541;Reactome: R-HSA-2559580;Reactome: R-HSA-2559585	"Ub-specific processing proteases";"Regulation of TP53 Activity through Phosphorylation";"Regulation of TP53 Degradation";"Regulation of TP53 Activity through Methylation";"Stabilization of p53";"Oxidative Stress Induced Senescence";"Oncogene Induced Senescence"
LHES001727-PA	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
LHES010287-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
LHES007120-PA	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
LHES007910-PA	6	MetaCyc: PWY-6722;MetaCyc: PWY-5789;Reactome: R-HSA-196780;MetaCyc: PWY-5743;MetaCyc: PWY-4381;MetaCyc: PWY-5744	"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation"
LHES007113-PA	2	Reactome: R-HSA-877300;Reactome: R-HSA-909733	"Interferon gamma signaling";"Interferon alpha/beta signaling"
LHES013446-PA	3	Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network"
LHES012441-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
LHES015019-PA	3	Reactome: R-HSA-6806664;KEGG: 00130+1.17.4.4;MetaCyc: PWY-7999	"Metabolism of vitamin K";"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle"
LHES012109-PA	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
LHES003681-PA	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
LHES013009-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
LHES002653-PA	6	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
LHES004517-PA	11	Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-75955	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation"
LHES012842-PA	7	Reactome: R-HSA-70221;MetaCyc: PWY-5941;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6737;MetaCyc: PWY-7238;Reactome: R-HSA-6798695;MetaCyc: PWY-6724	"Glycogen breakdown (glycogenolysis)";"Glycogen degradation II";"Starch and sucrose metabolism";"Starch degradation V";"Sucrose biosynthesis II";"Neutrophil degranulation";"Starch degradation II"
LHES007961-PA	40	Reactome: R-HSA-6796648;Reactome: R-HSA-8851708;Reactome: R-HSA-674695;Reactome: R-HSA-72165;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-167152;Reactome: R-HSA-168325;Reactome: R-HSA-73776;Reactome: R-HSA-167290;Reactome: R-HSA-203927;Reactome: R-HSA-6782135;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-72203;Reactome: R-HSA-5601884;Reactome: R-HSA-167160;Reactome: R-HSA-167238;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-6781823;Reactome: R-HSA-167287;Reactome: R-HSA-76042;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-72163;Reactome: R-HSA-6803529;Reactome: R-HSA-5578749;Reactome: R-HSA-6807505;Reactome: R-HSA-6781827;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-5617472;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167162;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-167172	"TP53 Regulates Transcription of DNA Repair Genes";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Pre-transcription Events";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"Viral Messenger RNA Synthesis";"RNA Polymerase II Promoter Escape";"Pausing and recovery of HIV elongation";"MicroRNA (miRNA) biogenesis";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"Processing of Capped Intron-Containing Pre-mRNA";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Capping";"Estrogen-dependent gene expression";"Formation of TC-NER Pre-Incision Complex";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Major Pathway";"FGFR2 alternative splicing";"Transcriptional regulation by small RNAs";"RNA polymerase II transcribes snRNA genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II HIV Promoter Escape";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"Transcription of the HIV genome"
LHES003755-PA	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
LHES003038-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
LHES000261-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
LHES012478-PA	5	Reactome: R-HSA-2426168;Reactome: R-HSA-75105;Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-163765	"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression"
LHES008675-PA	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
LHES013066-PA	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
LHES016446-PA	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
LHES011005-PA	10	MetaCyc: PWY-6361;MetaCyc: PWY-6554;MetaCyc: PWY-6372;Reactome: R-HSA-1855191;MetaCyc: PWY-4661;MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6362;KEGG: 00562+2.7.1.158	"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism"
LHES005299-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
LHES014630-PA	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
LHES007555-PA	5	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-446388;Reactome: R-HSA-8964616	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK";"Regulation of cytoskeletal remodeling and cell spreading by IPP complex components";"G beta:gamma signalling through CDC42"
LHES009022-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
LHES016722-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
LHES000517-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
LHES016924-PA	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
LHES006018-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
LHES000447-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
LHES004044-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
LHES008549-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
LHES014024-PA	2	Reactome: R-HSA-171319;Reactome: R-HSA-3214847	"Telomere Extension By Telomerase";"HATs acetylate histones"
LHES007738-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
LHES012538-PA	7	Reactome: R-HSA-165054;Reactome: R-HSA-203927;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-1655829;Reactome: R-HSA-6784531	"Rev-mediated nuclear export of HIV RNA";"MicroRNA (miRNA) biogenesis";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"tRNA processing in the nucleus"
LHES014623-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
LHES007810-PA	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
LHES003891-PA	3	Reactome: R-HSA-9645722;Reactome: R-HSA-140837;Reactome: R-HSA-111471	"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Intrinsic Pathway of Fibrin Clot Formation";"Apoptotic factor-mediated response"
LHES003833-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
LHES001275-PA	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
LHES012426-PA	14	Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167290	"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation"
LHES003242-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
LHES013772-PA	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
LHES009467-PA	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
LHES014416-PA	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
LHES008914-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
LHES003054-PA	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
LHES014569-PA	5	KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921;MetaCyc: PWY-7922	"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)"
LHES007423-PA	7	KEGG: 00250+6.3.5.5;MetaCyc: PWY-7790;MetaCyc: PWY-7791;MetaCyc: PWY-7400;KEGG: 00240+6.3.5.5;MetaCyc: PWY-5154;MetaCyc: PWY-5686	"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis II";"UMP biosynthesis III";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"UMP biosynthesis I"
LHES006189-PA	1	Reactome: R-HSA-5676934	"Protein repair"
LHES004165-PA	3	MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33	"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
LHES002241-PA	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
LHES009919-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
LHES001205-PA	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
LHES004268-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
LHES012822-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
LHES016918-PA	6	Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit"
LHES009452-PA	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
LHES012554-PA	11	Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-3214847;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-5689880;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-674695	"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HATs acetylate histones";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"Ub-specific processing proteases";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events"
LHES013089-PA	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-6598	"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis"
LHES006404-PA	10	KEGG: 04070+2.7.1.153;Reactome: R-HSA-1660499;Reactome: R-HSA-9027276;KEGG: 05165+2.7.1.153;KEGG: 05163+2.7.1.153;MetaCyc: PWY-6352;KEGG: 00562+2.7.1.153;KEGG: 04150+2.7.1.153;KEGG: 05170+2.7.1.153;KEGG: 04151+2.7.1.153	"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human papillomavirus infection";"Human cytomegalovirus infection";"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
LHES002692-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
LHES003256-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
LHES010228-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
LHES007191-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
LHES013490-PA	1	Reactome: R-HSA-8951664	"Neddylation"
LHES003043-PA	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
LHES005410-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
LHES003567-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
LHES015054-PA	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
LHES001314-PA	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
LHES004578-PA	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
LHES013768-PA	18	Reactome: R-HSA-1482922;MetaCyc: PWY-7417;Reactome: R-HSA-1482801;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-7783;Reactome: R-HSA-1483166;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-8053;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416	"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PS";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Acyl chain remodelling of PG";"Plasmalogen degradation";"Synthesis of PA";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)"
LHES011153-PA	40	Reactome: R-HSA-167160;Reactome: R-HSA-167238;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-72203;Reactome: R-HSA-5601884;Reactome: R-HSA-167158;Reactome: R-HSA-72163;Reactome: R-HSA-6803529;Reactome: R-HSA-6781823;Reactome: R-HSA-167287;Reactome: R-HSA-76042;Reactome: R-HSA-113418;Reactome: R-HSA-6781827;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-5578749;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-5617472;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-8851708;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-72165;Reactome: R-HSA-75953;Reactome: R-HSA-203927;Reactome: R-HSA-6782210;Reactome: R-HSA-167152;Reactome: R-HSA-168325;Reactome: R-HSA-73776;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-6782135;Reactome: R-HSA-77075	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Capping";"Estrogen-dependent gene expression";"Processing of Capped Intron-Containing Pre-mRNA";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Major Pathway";"FGFR2 alternative splicing";"Formation of TC-NER Pre-Incision Complex";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"Transcriptional regulation by small RNAs";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation";"MicroRNA (miRNA) biogenesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"Viral Messenger RNA Synthesis";"RNA Polymerase II Promoter Escape";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE"
LHES005645-PA	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
LHES003984-PA	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
LHES004304-PA	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
LHES008967-PA	3	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
LHES015147-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
LHES004285-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
LHES000852-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
LHES012717-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
LHES003464-PA	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
LHES006556-PA	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
LHES002539-PA	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
LHES011771-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
LHES008169-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
LHES001516-PA	7	MetaCyc: PWY-5659;MetaCyc: PWY-882;KEGG: 00520+5.4.2.8;MetaCyc: PWY-7586;MetaCyc: PWY-7456;KEGG: 00051+5.4.2.8;Reactome: R-HSA-446205	"GDP-mannose biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Beta-(1,4)-mannan degradation";"Fructose and mannose metabolism";"Synthesis of GDP-mannose"
LHES008431-PA	2	KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
LHES007570-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
LHES008910-PA	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
LHES005164-PA	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling"
LHES011960-PA	8	Reactome: R-HSA-9613354;Reactome: R-HSA-380972;Reactome: R-HSA-1445148;Reactome: R-HSA-6804756;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-9619483;Reactome: R-HSA-2151209	"Lipophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Activation of AMPK downstream of NMDARs";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation"
LHES011455-PA	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
LHES009237-PA	7	Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-166208	"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"Macroautophagy";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling"
LHES004827-PA	4	Reactome: R-HSA-71240;Reactome: R-HSA-210991;Reactome: R-HSA-352230;Reactome: R-HSA-5660862	"Tryptophan catabolism";"Basigin interactions";"Amino acid transport across the plasma membrane";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)"
LHES006173-PA	8	Reactome: R-HSA-437239;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"Recycling pathway of L1";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
LHES014072-PA	5	MetaCyc: PWY-6692;MetaCyc: PWY-7279;MetaCyc: PWY-3781;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7082	"Fe(II) oxidation";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)"
LHES007289-PA	1	Reactome: R-HSA-8951664	"Neddylation"
LHES003651-PA	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
LHES008565-PA	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
LHES006778-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
LHES012866-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
LHES015873-PA	2	KEGG: 00730+2.8.1.7;MetaCyc: PWY-7250	"Thiamine metabolism";"[2Fe-2S] iron-sulfur cluster biosynthesis"
LHES008508-PA	52	Reactome: R-HSA-9018519;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-167160;Reactome: R-HSA-73863;Reactome: R-HSA-72203;Reactome: R-HSA-5601884;Reactome: R-HSA-76061;Reactome: R-HSA-6803529;Reactome: R-HSA-427413;Reactome: R-HSA-167158;Reactome: R-HSA-72163;Reactome: R-HSA-76042;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-167287;Reactome: R-HSA-6781827;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-5578749;Reactome: R-HSA-167172;Reactome: R-HSA-167243;Reactome: R-HSA-167162;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-5617472;Reactome: R-HSA-167200;Reactome: R-HSA-73772;Reactome: R-HSA-73980;Reactome: R-HSA-73779;Reactome: R-HSA-72165;Reactome: R-HSA-75953;Reactome: R-HSA-749476;Reactome: R-HSA-8851708;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-1834949;Reactome: R-HSA-73762;Reactome: R-HSA-203927;Reactome: R-HSA-73776;Reactome: R-HSA-167290;Reactome: R-HSA-6782210;Reactome: R-HSA-167152;Reactome: R-HSA-168325;Reactome: R-HSA-167246;Reactome: R-HSA-5250924;Reactome: R-HSA-77075;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-6782135	"Estrogen-dependent gene expression";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Termination";"Processing of Capped Intron-Containing Pre-mRNA";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"FGFR2 alternative splicing";"NoRC negatively regulates rRNA expression";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"HIV elongation arrest and recovery";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"Transcriptional regulation by small RNAs";"Transcription of the HIV genome";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II HIV Promoter Escape";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Abortive And Retractive Initiation";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase I Transcription Initiation";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Promoter Escape";"Pausing and recovery of HIV elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"Viral Messenger RNA Synthesis";"Tat-mediated elongation of the HIV-1 transcript";"B-WICH complex positively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Dual incision in TC-NER"
LHES007849-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
LHES006750-PA	13	Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-6791226	"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol"
LHES015792-PA	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
LHES011324-PA	1	Reactome: R-HSA-70350	"Fructose catabolism"
LHES012973-PA	11	Reactome: R-HSA-174437;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-69166;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554	"Removal of the Flap Intermediate from the C-strand";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Removal of the Flap Intermediate";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
LHES003896-PA	3	KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;MetaCyc: PWY-7382	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)"
LHES008345-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES007478-PA	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
LHES012044-PA	11	Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-210744;Reactome: R-HSA-350054;Reactome: R-HSA-72163;Reactome: R-HSA-1912408;Reactome: R-HSA-2894862;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-2173796;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway";"mRNA Splicing - Major Pathway";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NOTCH1 Intracellular Domain Regulates Transcription"
LHES001972-PA	16	Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557	"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis"
LHES000803-PA	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
LHES016840-PA	5	Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-5083630;Reactome: R-HSA-1912420;Reactome: R-HSA-1912399	"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"Defective LFNG causes SCDO3";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Processing in the Endoplasmic Reticulum"
LHES017181-PA	2	KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10	"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis"
LHES010944-PA	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
LHES013929-PA	1	Reactome: R-HSA-9640463	"Wax biosynthesis"
LHES013400-PA	16	Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-1799339	"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane"
LHES012405-PA	5	Reactome: R-HSA-1912399;Reactome: R-HSA-350054;Reactome: R-HSA-5083630;Reactome: R-HSA-1912420;Reactome: R-HSA-1912408	"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Notch-HLH transcription pathway";"Defective LFNG causes SCDO3";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Transcription and Translation"
LHES001048-PA	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
LHES009440-PA	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
LHES006806-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
LHES014046-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
LHES005909-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
LHES006772-PA	1	Reactome: R-HSA-8951664	"Neddylation"
LHES008243-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
LHES006003-PA	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847	"DNA Damage Recognition in GG-NER";"UCH proteinases";"HATs acetylate histones"
LHES005854-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
LHES001209-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
LHES007081-PA	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
LHES002770-PA	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
LHES012309-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
LHES007786-PA	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
LHES013736-PA	8	MetaCyc: PWY-7734;KEGG: 00630+3.5.1.9;MetaCyc: PWY-7733;MetaCyc: PWY-5651;MetaCyc: PWY-7717;MetaCyc: PWY-7765;MetaCyc: PWY-6309;KEGG: 00380+3.5.1.9	"Quinoxaline-2-carboxylate biosynthesis";"Glyoxylate and dicarboxylate metabolism";"3-hydroxyquinaldate biosynthesis";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism"
LHES014148-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
LHES003534-PA	1	Reactome: R-HSA-8951664	"Neddylation"
LHES009532-PA	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
LHES002046-PA	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
LHES012845-PA	3	MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21;Reactome: R-HSA-196807	"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism"
LHES003828-PA	14	MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7036	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II"
LHES015390-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
LHES003877-PA	13	Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-6791226	"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol"
LHES007099-PA	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
LHES013903-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
LHES005639-PA	10	KEGG: 00030+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00680+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-7385;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.11	"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis";"Galactose metabolism"
LHES004953-PA	7	KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-7039	"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule"
LHES002154-PA	5	Reactome: R-HSA-6811440;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"Intra-Golgi traffic"
LHES007943-PA	2	Reactome: R-HSA-5205685;Reactome: R-HSA-1268020	"Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import"
LHES004488-PA	1	Reactome: R-HSA-1483101	"Synthesis of PS"
LHES015740-PA	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
LHES008221-PA	6	MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
LHES007526-PA	6	Reactome: R-HSA-1268020;KEGG: 00630+4.2.1.3;Reactome: R-HSA-71403;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00720+4.2.1.3	"Mitochondrial protein import";"Glyoxylate and dicarboxylate metabolism";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Carbon fixation pathways in prokaryotes"
LHES008560-PA	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
LHES012235-PA	4	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
LHES003283-PA	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
LHES009133-PA	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
LHES012488-PA	6	Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit"
LHES012912-PA	6	KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-975578;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143	"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis"
LHES009118-PA	7	Reactome: R-HSA-3214842;Reactome: R-HSA-9018519;Reactome: R-HSA-8943724;Reactome: R-HSA-9029569;Reactome: R-HSA-5625886;Reactome: R-HSA-3214815;Reactome: R-HSA-983231	"HDMs demethylate histones";"Estrogen-dependent gene expression";"Regulation of PTEN gene transcription";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HDACs deacetylate histones";"Factors involved in megakaryocyte development and platelet production"
LHES008517-PA	56	Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-8939236;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-69601;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-8951664;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-5362768;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-68827	"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neddylation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"ABC-family proteins mediated transport";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Degradation of AXIN";"CDT1 association with the CDC6:ORC:origin complex"
LHES006372-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES009592-PA	6	Reactome: R-HSA-73930;Reactome: R-HSA-110362;Reactome: R-HSA-5651801;Reactome: R-HSA-110357;Reactome: R-HSA-73933;Reactome: R-HSA-110373	"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"POLB-Dependent Long Patch Base Excision Repair";"PCNA-Dependent Long Patch Base Excision Repair";"Displacement of DNA glycosylase by APEX1";"Resolution of Abasic Sites (AP sites)";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway"
LHES015682-PA	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
LHES001225-PA	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
LHES008281-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
LHES005709-PA	16	Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-2408557	"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis"
LHES016509-PA	2	Reactome: R-HSA-5658442;Reactome: R-HSA-6802953	"Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants"
LHES010060-PA	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
LHES002941-PA	8	KEGG: 05163+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"Signaling by Hippo";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway"
LHES008333-PA	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
LHES015690-PA	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
LHES000251-PA	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
LHES017233-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
LHES015478-PA	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
LHES005290-PA	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
LHES011472-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
LHES008610-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
LHES005883-PA	1	Reactome: R-HSA-114608	"Platelet degranulation"
LHES013386-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
LHES006031-PA	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
LHES005569-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
LHES015403-PA	1	Reactome: R-HSA-1483255	"PI Metabolism"
LHES012310-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
LHES016973-PA	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
LHES003743-PA	6	Reactome: R-HSA-8862803;MetaCyc: PWY-6854;Reactome: R-HSA-8950505;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Ethylene biosynthesis III (microbes)";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis"
LHES011346-PA	6	MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23	"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Sphingolipid metabolism";"Other glycan degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series"
LHES009483-PA	3	Reactome: R-HSA-71336;KEGG: 00030+1.1.1.44;KEGG: 00480+1.1.1.44	"Pentose phosphate pathway";"Pentose phosphate pathway";"Glutathione metabolism"
LHES003447-PA	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
LHES015684-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
LHES008028-PA	12	KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-6728;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-6969;MetaCyc: PWY-7384;MetaCyc: PWY-5537	"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate V"
LHES003254-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
LHES011474-PA	14	Reactome: R-HSA-203927;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-426486;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700	"MicroRNA (miRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Small interfering RNA (siRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
LHES003796-PA	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection"
LHES004782-PA	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090	"Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures"
LHES010513-PA	7	Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76066	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
LHES009165-PA	1	KEGG: 00230+3.6.1.29	"Purine metabolism"
LHES006386-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES005441-PA	6	Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
LHES008706-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
LHES000576-PA	12	Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-8953750;Reactome: R-HSA-5685938;Reactome: R-HSA-5685939;Reactome: R-HSA-5685942	"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Transcriptional Regulation by E2F6";"HDR through Single Strand Annealing (SSA)";"HDR through MMEJ (alt-NHEJ)";"HDR through Homologous Recombination (HRR)"
LHES015706-PA	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
LHES012447-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
LHES014362-PA	7	Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA"
LHES015302-PA	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
LHES004711-PA	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
LHES006065-PA	5	Reactome: R-HSA-1257604;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757	"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation"
LHES013424-PA	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
LHES007019-PA	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
LHES005043-PA	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
LHES007506-PA	17	Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167290;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167242;KEGG: 04658+3.1.3.16;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-167158;KEGG: 04660+3.1.3.16;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167238	"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Th1 and Th2 cell differentiation";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"T cell receptor signaling pathway";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation"
LHES008972-PA	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
LHES006171-PA	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
LHES013290-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
LHES006506-PA	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
LHES013304-PA	6	Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-450513	"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
LHES003404-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
LHES009817-PA	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
LHES002940-PA	6	KEGG: 00564+1.1.5.3;MetaCyc: PWY-6952;Reactome: R-HSA-163560;MetaCyc: PWY-4261;MetaCyc: PWY-6118;Reactome: R-HSA-1483166	"Glycerophospholipid metabolism";"Glycerophosphodiester degradation";"Triglyceride catabolism";"Glycerol degradation I";"Glycerol-3-phosphate shuttle";"Synthesis of PA"
LHES003417-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES004606-PA	5	Reactome: R-HSA-5221030;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-3108214	"TET1,2,3 and TDG demethylate DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins"
LHES010548-PA	9	Reactome: R-HSA-9656256;Reactome: R-HSA-110329;Reactome: R-HSA-5649702;Reactome: R-HSA-9656255;Reactome: R-HSA-9657050;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110330;Reactome: R-HSA-110331	"Defective OGG1 Substrate Processing";"Cleavage of the damaged pyrimidine";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Defective OGG1 Substrate Binding";"Defective OGG1 Localization";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine"
LHES013675-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
LHES007443-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
LHES001487-PA	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
LHES006190-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
LHES015853-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
LHES003781-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
LHES001166-PA	10	Reactome: R-HSA-6814122;Reactome: R-HSA-8934903;Reactome: R-HSA-445144;Reactome: R-HSA-6804756;Reactome: R-HSA-201688;Reactome: R-HSA-2514853;Reactome: R-HSA-8939243;Reactome: R-HSA-1483191;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Receptor Mediated Mitophagy";"Signal transduction by L1";"Regulation of TP53 Activity through Phosphorylation";"WNT mediated activation of DVL";"Condensation of Prometaphase Chromosomes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Synthesis of PC";"Neutrophil degranulation";"Regulation of PTEN stability and activity"
LHES002596-PA	8	Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-69166	"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate"
LHES001663-PA	6	Reactome: R-HSA-6798695;KEGG: 00380+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241	"Neutrophil degranulation";"Tryptophan metabolism";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import"
LHES012901-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
LHES005284-PA	3	Reactome: R-HSA-4419969;Reactome: R-HSA-2995383;Reactome: R-HSA-2980766	"Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown"
LHES005100-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
LHES008735-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
LHES000016-PA	7	Reactome: R-HSA-381033;Reactome: R-HSA-3371453;Reactome: R-HSA-983170;Reactome: R-HSA-381070;Reactome: R-HSA-381042;Reactome: R-HSA-114608;Reactome: R-HSA-381183	"ATF6 (ATF6-alpha) activates chaperones";"Regulation of HSF1-mediated heat shock response";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"IRE1alpha activates chaperones";"PERK regulates gene expression";"Platelet degranulation";"ATF6 (ATF6-alpha) activates chaperone genes"
LHES003125-PA	1	Reactome: R-HSA-8951664	"Neddylation"
LHES003688-PA	2	Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
LHES008823-PA	2	Reactome: R-HSA-2243919;Reactome: R-HSA-1566948	"Crosslinking of collagen fibrils";"Elastic fibre formation"
LHES013714-PA	26	Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-190861;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-389977;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-983189;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-389960;Reactome: R-HSA-8955332	"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"Gap junction assembly";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Post-chaperonin tubulin folding pathway";"Recycling pathway of L1";"MHC class II antigen presentation";"HCMV Early Events";"Kinesins";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"Formation of tubulin folding intermediates by CCT/TriC";"Carboxyterminal post-translational modifications of tubulin"
LHES015432-PA	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
LHES012260-PA	6	Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-176187	"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of ATR in response to replication stress"
LHES001037-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
LHES003554-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
LHES003334-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
LHES015306-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
LHES012521-PA	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
LHES011933-PA	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
LHES003950-PA	5	MetaCyc: PWY-6168;KEGG: 00740+2.7.1.26;Reactome: R-HSA-196843;MetaCyc: PWY-5523;MetaCyc: PWY-7863	"Flavin biosynthesis III (fungi)";"Riboflavin metabolism";"Vitamin B2 (riboflavin) metabolism";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Roseoflavin biosynthesis"
LHES014184-PA	12	Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-6804756;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-6796648	"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes"
LHES006442-PA	16	Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72695	"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex"
LHES009425-PA	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
LHES002911-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
LHES017105-PA	6	Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695	"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex"
LHES000171-PA	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
LHES006425-PA	11	Reactome: R-HSA-380270;Reactome: R-HSA-6807878;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-3371497;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518	"Recruitment of mitotic centrosome proteins and complexes";"COPI-mediated anterograde transport";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2"
LHES002260-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
LHES009410-PA	1	Reactome: R-HSA-446193	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
LHES011360-PA	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
LHES007984-PA	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
LHES009622-PA	33	Reactome: R-HSA-2500257;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-159236;Reactome: R-HSA-2467813;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-68877;Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-141444;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-9648025;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-5663220;Reactome: R-HSA-4570464	"Resolution of Sister Chromatid Cohesion";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Separation of Sister Chromatids";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"Mitotic Prometaphase";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"EML4 and NUDC in mitotic spindle formation";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"RHO GTPases Activate Formins";"SUMOylation of RNA binding proteins"
LHES002473-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
LHES015942-PA	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
LHES009007-PA	4	Reactome: R-HSA-983168;Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952	"Antigen processing: Ubiquitination & Proteasome degradation";"Macroautophagy";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions"
LHES002526-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
LHES006186-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
LHES003707-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
LHES004139-PA	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
LHES017123-PA	8	Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-8953750;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-6803207;Reactome: R-HSA-6798695;Reactome: R-HSA-111463	"Formation of apoptosome";"Regulation of the apoptosome activity";"Transcriptional Regulation by E2F6";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Neutrophil degranulation";"SMAC (DIABLO) binds to IAPs"
LHES001713-PA	12	KEGG: 00280+5.1.99.1;MetaCyc: PWY-5743;MetaCyc: PWY-7854;KEGG: 00720+5.1.99.1;MetaCyc: PWY-5741;MetaCyc: PWY-6728;KEGG: 00630+5.1.99.1;Reactome: R-HSA-71032;MetaCyc: PWY-8086;KEGG: 00640+5.1.99.1;MetaCyc: PWY-7384;MetaCyc: PWY-5789	"Valine, leucine and isoleucine degradation";"3-hydroxypropanoate cycle";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Carbon fixation pathways in prokaryotes";"Ethylmalonyl-coa pathway";"Methylaspartate cycle";"Glyoxylate and dicarboxylate metabolism";"Propionyl-CoA catabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"3-hydroxypropanoate/4-hydroxybutanate cycle"
LHES003525-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
LHES004981-PA	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
LHES009205-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
LHES015704-PA	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
LHES000024-PA	1	Reactome: R-HSA-1483166	"Synthesis of PA"
LHES013105-PA	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
LHES003967-PA	9	Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-76042	"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
LHES012804-PA	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
LHES003000-PA	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
LHES004825-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
LHES001676-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
LHES005319-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
LHES011130-PA	9	Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579	"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange"
LHES015339-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
LHES016156-PA	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
LHES015441-PA	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
LHES005855-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
LHES001307-PA	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
LHES006541-PA	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
LHES002089-PA	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
LHES005275-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
LHES014587-PA	3	KEGG: 00670+2.1.2.5;KEGG: 00340+2.1.2.5;MetaCyc: PWY-5030	"One carbon pool by folate";"Histidine metabolism";"L-histidine degradation III"
LHES014217-PA	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
LHES015610-PA	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
LHES005705-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
LHES003814-PA	12	Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-6804756;Reactome: R-HSA-167238	"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Regulation of TP53 Activity through Phosphorylation";"Pausing and recovery of Tat-mediated HIV elongation"
LHES002674-PA	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
LHES005318-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
LHES015868-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
LHES016710-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
LHES010531-PA	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
LHES003279-PA	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
LHES012710-PA	4	Reactome: R-HSA-390247;KEGG: 00410+4.1.1.9;Reactome: R-HSA-9033241;KEGG: 00640+4.1.1.9	"Beta-oxidation of very long chain fatty acids";"beta-Alanine metabolism";"Peroxisomal protein import";"Propanoate metabolism"
LHES004233-PA	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
LHES000298-PA	1	Reactome: R-HSA-211981	"Xenobiotics"
LHES000933-PA	9	MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Other glycan degradation";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis"
LHES000989-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
LHES003053-PA	1	Reactome: R-HSA-5334118	"DNA methylation"
LHES000270-PA	1	Reactome: R-HSA-8951664	"Neddylation"
LHES006034-PA	56	Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-187577;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-5687128;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-382556	"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"SCF(Skp2)-mediated degradation of p27/p21";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"MAPK6/MAPK4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neddylation";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"ABC-family proteins mediated transport"
LHES003269-PA	3	Reactome: R-HSA-6798695;MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9	"Neutrophil degranulation";"Glutamate removal from folates";"Folate biosynthesis"
LHES016294-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
LHES014989-PA	7	MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11	"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system"
LHES003443-PA	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
LHES008670-PA	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
LHES009677-PA	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
LHES013008-PA	9	Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-167172	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome"
LHES006969-PA	3	Reactome: R-HSA-6783310;Reactome: R-HSA-5689880;Reactome: R-HSA-110314	"Fanconi Anemia Pathway";"Ub-specific processing proteases";"Recognition of DNA damage by PCNA-containing replication complex"
LHES007755-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
LHES004589-PA	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
LHES011183-PA	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
LHES000877-PA	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
LHES004478-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
LHES003476-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
LHES011946-PA	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
LHES003164-PA	3	MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2	"ATP biosynthesis";"Photosynthesis";"Oxidative phosphorylation"
LHES002232-PA	5	Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5625740	"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs"
LHES016147-PA	1	Reactome: R-HSA-8951664	"Neddylation"
LHES002439-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
LHES012302-PA	2	MetaCyc: PWY-7286;MetaCyc: PWY-7285	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis"
LHES003592-PA	2	Reactome: R-HSA-5663220;Reactome: R-HSA-376176	"RHO GTPases Activate Formins";"Signaling by ROBO receptors"
LHES016601-PA	6	Reactome: R-HSA-73817;Reactome: R-HSA-196780;KEGG: 00230+6.3.4.13;MetaCyc: PWY-6121;MetaCyc: PWY-6277;MetaCyc: PWY-6122	"Purine ribonucleoside monophosphate biosynthesis";"Biotin transport and metabolism";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II"
LHES016861-PA	4	Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-1799339	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane"
LHES006172-PA	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
LHES007382-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
LHES016279-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
LHES013798-PA	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
LHES015294-PA	1	Reactome: R-HSA-71288	"Creatine metabolism"
LHES011001-PA	11	KEGG: 00910+6.3.1.2;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6549;Reactome: R-HSA-8964539;Reactome: R-HSA-210455;KEGG: 00630+6.3.1.2;MetaCyc: PWY-381;MetaCyc: PWY-6964;MetaCyc: PWY-5675;MetaCyc: PWY-6963;KEGG: 00250+6.3.1.2	"Nitrogen metabolism";"Arginine biosynthesis";"L-glutamine biosynthesis III";"Glutamate and glutamine metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle II";"Nitrate reduction V (assimilatory)";"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism"
LHES010524-PA	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
LHES000449-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
LHES004706-PA	8	MetaCyc: PWY-7765;MetaCyc: PWY-7717;KEGG: 00380+3.5.1.9;MetaCyc: PWY-6309;KEGG: 00630+3.5.1.9;MetaCyc: PWY-7734;MetaCyc: PWY-5651;MetaCyc: PWY-7733	"3-hydroxy-4-methyl-anthranilate biosynthesis II";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"Tryptophan metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glyoxylate and dicarboxylate metabolism";"Quinoxaline-2-carboxylate biosynthesis";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxyquinaldate biosynthesis"
LHES002426-PA	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
LHES005624-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
LHES000457-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
LHES016201-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
LHES009500-PA	3	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
LHES015405-PA	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
LHES002032-PA	3	Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-191859	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"snRNP Assembly"
LHES008397-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
LHES004807-PA	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214815	"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones"
LHES010582-PA	13	Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit"
LHES012399-PA	4	MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737;Reactome: R-HSA-70688	"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism"
LHES016784-PA	6	MetaCyc: PWY-5941;Reactome: R-HSA-70221;KEGG: 00500+2.4.1.1;MetaCyc: PWY-6731;MetaCyc: PWY-6737;MetaCyc: PWY-7238	"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism";"Starch degradation III";"Starch degradation V";"Sucrose biosynthesis II"
LHES012810-PA	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
LHES014464-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES000855-PA	1	Reactome: R-HSA-8951664	"Neddylation"
LHES012358-PA	7	MetaCyc: PWY-7255;Reactome: R-HSA-5578999;KEGG: 00270+6.3.2.2;KEGG: 00480+6.3.2.2;MetaCyc: PWY-8043;Reactome: R-HSA-174403;MetaCyc: PWY-6840	"Ergothioneine biosynthesis I (bacteria)";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Cysteine and methionine metabolism";"Glutathione metabolism";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Homoglutathione biosynthesis"
LHES000865-PA	2	KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668	"Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
LHES006802-PA	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
LHES004615-PA	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
LHES015677-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
LHES007618-PA	16	Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72702	"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition"
LHES006632-PA	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
LHES010405-PA	6	Reactome: R-HSA-1474228;Reactome: R-HSA-381426;Reactome: R-HSA-186797;Reactome: R-HSA-8949275;Reactome: R-HSA-216083;Reactome: R-HSA-8957275	"Degradation of the extracellular matrix";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Signaling by PDGF";"RUNX3 Regulates Immune Response and Cell Migration";"Integrin cell surface interactions";"Post-translational protein phosphorylation"
LHES014400-PA	5	KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22	"Sphingolipid metabolism";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Glycerolipid metabolism"
LHES003960-PA	11	Reactome: R-HSA-2559580;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-450302;Reactome: R-HSA-4420097;KEGG: 04714+2.7.11.1;Reactome: R-HSA-171007;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Oxidative Stress Induced Senescence";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"activated TAK1 mediates p38 MAPK activation";"VEGFA-VEGFR2 Pathway";"Thermogenesis";"p38MAPK events";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway"
LHES003247-PA	13	MetaCyc: PWY-6969;MetaCyc: PWY-5392;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5537;MetaCyc: PWY-7384;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5690	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Pyruvate fermentation to acetate V";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)"
LHES008521-PA	1	Reactome: R-HSA-6787639	"GDP-fucose biosynthesis"
LHES009657-PA	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
LHES004018-PA	3	MetaCyc: PWY-5987;MetaCyc: PWY-5996;Reactome: R-HSA-75105	"Sorgoleone biosynthesis";"Oleate biosynthesis II (animals and fungi)";"Fatty acyl-CoA biosynthesis"
LHES012378-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
LHES011248-PA	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
LHES008568-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
LHES014949-PA	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
LHES008197-PA	3	MetaCyc: PWY-6689;MetaCyc: PWY-7803;Reactome: R-HSA-6784531	"Trna splicing I";"Trna splicing II";"tRNA processing in the nucleus"
LHES016202-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
LHES000765-PA	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
LHES004464-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
LHES003811-PA	2	Reactome: R-HSA-418555;Reactome: R-HSA-444821	"G alpha (s) signalling events";"Relaxin receptors"
LHES002495-PA	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
LHES006110-PA	5	Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis"
LHES013468-PA	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
LHES008060-PA	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
LHES013323-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
LHES003765-PA	6	Reactome: R-HSA-6798695;Reactome: R-HSA-1222556;Reactome: R-HSA-3299685;Reactome: R-HSA-4420097;Reactome: R-HSA-1236973;Reactome: R-HSA-5668599	"Neutrophil degranulation";"ROS and RNS production in phagocytes";"Detoxification of Reactive Oxygen Species";"VEGFA-VEGFR2 Pathway";"Cross-presentation of particulate exogenous antigens (phagosomes)";"RHO GTPases Activate NADPH Oxidases"
LHES002231-PA	5	Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-75035	"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"
LHES011762-PA	56	Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-68827;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-1236978;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-5362768;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-187577;Reactome: R-HSA-8939236;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-174084	"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"ABC-family proteins mediated transport";"Degradation of DVL";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neddylation";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"SCF(Skp2)-mediated degradation of p27/p21";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C"
LHES009418-PA	1	Reactome: R-HSA-400253	"Circadian Clock"
LHES015713-PA	3	Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
LHES014579-PA	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
LHES014045-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
LHES001694-PA	6	MetaCyc: PWY-6722;MetaCyc: PWY-5789;Reactome: R-HSA-196780;MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-4381	"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (bacteria and plants)"
LHES003831-PA	13	Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit"
LHES003734-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
LHES005422-PA	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
LHES016663-PA	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
LHES013479-PA	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
LHES000066-PA	6	Reactome: R-HSA-8874081;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090	"MET activates PTK2 signaling";"Collagen chain trimerization";"Collagen degradation";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures"
LHES006205-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
LHES003999-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
LHES006219-PA	6	Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-176187	"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress"
LHES004745-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
LHES002474-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
LHES001412-PA	13	Reactome: R-HSA-2022090;Reactome: R-HSA-2214320;Reactome: R-HSA-1650814;Reactome: R-HSA-3000171;Reactome: R-HSA-1474244;Reactome: R-HSA-2243919;Reactome: R-HSA-216083;Reactome: R-HSA-186797;Reactome: R-HSA-419037;Reactome: R-HSA-1442490;Reactome: R-HSA-3000178;Reactome: R-HSA-8948216;Reactome: R-HSA-3000157	"Assembly of collagen fibrils and other multimeric structures";"Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes";"Non-integrin membrane-ECM interactions";"Extracellular matrix organization";"Crosslinking of collagen fibrils";"Integrin cell surface interactions";"Signaling by PDGF";"NCAM1 interactions";"Collagen degradation";"ECM proteoglycans";"Collagen chain trimerization";"Laminin interactions"
LHES013539-PA	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
LHES003012-PA	2	Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
LHES005456-PA	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
LHES009658-PA	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
LHES002168-PA	12	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Mitotic Prometaphase"
LHES005393-PA	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
LHES013567-PA	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
LHES008825-PA	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
LHES010431-PA	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
LHES011840-PA	56	Reactome: R-HSA-174154;Reactome: R-HSA-8939236;Reactome: R-HSA-8939902;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-187577;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-1236974;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-5687128;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-1236978;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858	"APC/C:Cdc20 mediated degradation of Securin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX2 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"SCF(Skp2)-mediated degradation of p27/p21";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"ER-Phagosome pathway";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"MAPK6/MAPK4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"ABC-family proteins mediated transport";"Neddylation";"Cross-presentation of soluble exogenous antigens (endosomes)";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity"
LHES004049-PA	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
LHES012406-PA	1	Reactome: R-HSA-5578775	"Ion homeostasis"
LHES016463-PA	5	Reactome: R-HSA-8856825;Reactome: R-HSA-6798695;Reactome: R-HSA-6811440;Reactome: R-HSA-432722;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Neutrophil degranulation";"Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis";"Clathrin-mediated endocytosis"
LHES000845-PA	5	Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-163765	"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression"
LHES010562-PA	12	KEGG: 00564+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7416;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7417	"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Arachidonic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)"
LHES003166-PA	2	MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7	"[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism"
LHES012484-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
LHES011644-PA	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection"
LHES002937-PA	26	Reactome: R-HSA-9013695;Reactome: R-HSA-3899300;Reactome: R-HSA-201722;Reactome: R-HSA-918233;Reactome: R-HSA-5617472;Reactome: R-HSA-9013508;Reactome: R-HSA-1234158;Reactome: R-HSA-8866907;Reactome: R-HSA-3371568;Reactome: R-HSA-9614657;Reactome: R-HSA-5621575;Reactome: R-HSA-8941856;Reactome: R-HSA-381340;Reactome: R-HSA-9617629;Reactome: R-HSA-1368082;Reactome: R-HSA-2122947;Reactome: R-HSA-9018519;Reactome: R-HSA-210744;Reactome: R-HSA-2644606;Reactome: R-HSA-1989781;Reactome: R-HSA-3214847;Reactome: R-HSA-3134973;Reactome: R-HSA-933541;Reactome: R-HSA-2894862;Reactome: R-HSA-400253;Reactome: R-HSA-1912408	"NOTCH4 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"Formation of the beta-catenin:TCF transactivating complex";"TRAF3-dependent IRF activation pathway";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression by Hypoxia-inducible Factor";"Activation of the TFAP2 (AP-2) family of transcription factors";"Attenuation phase";"FOXO-mediated transcription of cell death genes";"CD209 (DC-SIGN) signaling";"RUNX3 regulates NOTCH signaling";"Transcriptional regulation of white adipocyte differentiation";"Regulation of FOXO transcriptional activity by acetylation";"RORA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"PPARA activates gene expression";"HATs acetylate histones";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"TRAF6 mediated IRF7 activation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Circadian Clock";"Pre-NOTCH Transcription and Translation"
LHES006291-PA	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
LHES006443-PA	1	KEGG: 00970+6.1.1.1	"Aminoacyl-tRNA biosynthesis"
LHES011080-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
LHES004955-PA	7	MetaCyc: PWY-6367;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204	"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol"
LHES013763-PA	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
LHES013217-PA	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
LHES005513-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
LHES008488-PA	1	Reactome: R-HSA-8963693	"Aspartate and asparagine metabolism"
LHES009033-PA	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
LHES004937-PA	6	MetaCyc: PWY-6368;KEGG: 04070+3.1.3.36;Reactome: R-HSA-194840;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855204	"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Rho GTPase cycle";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol"
LHES011182-PA	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
LHES000832-PA	20	Reactome: R-HSA-1257604;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-3371571;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;KEGG: 05165+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-9639288;KEGG: 04926+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-8943724	"PIP3 activates AKT signaling";"mTOR signaling pathway";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"HSF1-dependent transactivation";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"mTOR signalling";"Macroautophagy";"Human papillomavirus infection";"CD28 dependent PI3K/Akt signaling";"Amino acids regulate mTORC1";"Relaxin signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Regulation of PTEN gene transcription"
LHES000627-PA	3	Reactome: R-HSA-983168;Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Protein ubiquitination"
LHES015244-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
LHES016350-PA	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
LHES005977-PA	4	MetaCyc: PWY-7511;Reactome: R-HSA-975144;Reactome: R-HSA-937039;Reactome: R-HSA-9020702	"Protein ubiquitination";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Interleukin-1 signaling"
LHES002128-PA	3	Reactome: R-HSA-500753;KEGG: 00240+1.3.5.2;MetaCyc: PWY-5686	"Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis I"
LHES001692-PA	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
LHES004487-PA	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
LHES014331-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
LHES016251-PA	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
LHES002351-PA	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
LHES005627-PA	5	KEGG: 00533+2.4.1.68;KEGG: 00513+2.4.1.68;KEGG: 00510+2.4.1.68;MetaCyc: PWY-7426;Reactome: R-HSA-975578	"Glycosaminoglycan biosynthesis - keratan sulfate";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway"
LHES005421-PA	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
LHES007479-PA	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
LHES013476-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
LHES000716-PA	8	Reactome: R-HSA-5083629;MetaCyc: PWY-7922;Reactome: R-HSA-5083633;Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979	"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)"
LHES006445-PA	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
LHES008064-PA	12	MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4	"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Arachidonic acid metabolism"
LHES005226-PA	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
LHES007482-PA	15	Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-9603505;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167243	"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"NTRK3 as a dependence receptor";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery"
LHES007782-PA	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
LHES009676-PA	52	Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-1236978;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-4608870;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-5607761;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-174154;Reactome: R-HSA-8939236;Reactome: R-HSA-8939902;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-180534	"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"ABC-family proteins mediated transport";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Degradation of AXIN";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"Cross-presentation of soluble exogenous antigens (endosomes)";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Asymmetric localization of PCP proteins";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"APC/C:Cdc20 mediated degradation of Securin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX2 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"ER-Phagosome pathway";"Interleukin-1 signaling";"Vpu mediated degradation of CD4"
LHES008509-PA	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
LHES000325-PA	5	Reactome: R-HSA-350054;Reactome: R-HSA-3214815;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
LHES011920-PA	3	MetaCyc: PWY-7833;MetaCyc: PWY-7831;Reactome: R-HSA-9033807	"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis"
LHES009523-PA	15	Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-113418	"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex"
LHES008965-PA	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
LHES014898-PA	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
LHES010373-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
LHES015934-PA	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
LHES007689-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
LHES000366-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
LHES016161-PA	1	Reactome: R-HSA-9640463	"Wax biosynthesis"
LHES002459-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES012964-PA	10	MetaCyc: PWY-6142;Reactome: R-HSA-70171;KEGG: 00010+5.3.1.1;KEGG: 00710+5.3.1.1;MetaCyc: PWY-7003;KEGG: 00051+5.3.1.1;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00562+5.3.1.1;Reactome: R-HSA-70263	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Inositol phosphate metabolism";"Gluconeogenesis"
LHES004624-PA	4	Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346	"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis"
LHES011364-PA	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
LHES004273-PA	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
LHES005472-PA	4	KEGG: 00230+3.5.1.5;MetaCyc: PWY-5704;KEGG: 00791+3.5.1.5;KEGG: 00220+3.5.1.5	"Purine metabolism";"Urea degradation II";"Atrazine degradation";"Arginine biosynthesis"
LHES001839-PA	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
LHES004265-PA	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
LHES006093-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
LHES008657-PA	11	Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-2979096;Reactome: R-HSA-193692;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-3928665;Reactome: R-HSA-2644606	"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
LHES014842-PA	1	Reactome: R-HSA-1614558	"Degradation of cysteine and homocysteine"
LHES001438-PA	11	Reactome: R-HSA-400253;Reactome: R-HSA-212436;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-400206;Reactome: R-HSA-383280;Reactome: R-HSA-381340;Reactome: R-HSA-2151201	"Circadian Clock";"Generic Transcription Pathway";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression";"Estrogen-dependent gene expression";"Regulation of lipid metabolism by PPARalpha";"Nuclear Receptor transcription pathway";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis"
LHES005338-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
LHES005655-PA	6	Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-8874081;Reactome: R-HSA-1442490;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814	"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"MET activates PTK2 signaling";"Collagen degradation";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes"
LHES011592-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
LHES011893-PA	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
LHES000084-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
LHES008223-PA	32	Reactome: R-HSA-6807505;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-167172;Reactome: R-HSA-72203;Reactome: R-HSA-167238;Reactome: R-HSA-167160;Reactome: R-HSA-9018519;Reactome: R-HSA-72086;Reactome: R-HSA-167287;Reactome: R-HSA-76042;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-72163;Reactome: R-HSA-6803529;Reactome: R-HSA-168325;Reactome: R-HSA-167152;Reactome: R-HSA-73776;Reactome: R-HSA-167290;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-8851708;Reactome: R-HSA-674695;Reactome: R-HSA-72165;Reactome: R-HSA-75953;Reactome: R-HSA-73779	"RNA polymerase II transcribes snRNA genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"Transcription of the HIV genome";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Estrogen-dependent gene expression";"mRNA Capping";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Major Pathway";"FGFR2 alternative splicing";"Viral Messenger RNA Synthesis";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Promoter Escape";"Pausing and recovery of HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Pre-transcription Events";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
LHES007474-PA	13	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416572;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3928663;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3928662;Reactome: R-HSA-5627117;Reactome: R-HSA-416482;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-4420097	"Human papillomavirus infection";"Relaxin signaling pathway";"Sema4D induced cell migration and growth-cone collapse";"mTOR signaling pathway";"EPHA-mediated growth cone collapse";"Thermogenesis";"EPHB-mediated forward signaling";"RHO GTPases Activate ROCKs";"G alpha (12/13) signalling events";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"VEGFA-VEGFR2 Pathway"
LHES000041-PA	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Neutrophil degranulation"
LHES009086-PA	5	Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72662;Reactome: R-HSA-72702	"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition"
LHES005414-PA	1	Reactome: R-HSA-8951664	"Neddylation"
LHES009849-PA	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
LHES004960-PA	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
LHES005233-PA	6	MetaCyc: PWY-5514;KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749;Reactome: R-HSA-446210;KEGG: 00520+5.4.2.3;MetaCyc: PWY-6906	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation"
LHES000867-PA	24	Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148	"Recycling pathway of L1";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Kinesins";"HCMV Early Events";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Gap junction assembly";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"Cilium Assembly";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
LHES007128-PA	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
LHES002496-PA	5	Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-73762	"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation"
LHES009986-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
LHES012532-PA	57	Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-5687128;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-187577;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-69017;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-8939236;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-9010553;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895	"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"MAPK6/MAPK4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"SCF(Skp2)-mediated degradation of p27/p21";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Regulation of expression of SLITs and ROBOs";"ABC-family proteins mediated transport";"Degradation of DVL";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Degradation of AXIN";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis"
LHES007163-PA	3	Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
LHES010413-PA	6	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-201722;Reactome: R-HSA-8866654;Reactome: R-HSA-5632684	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of the beta-catenin:TCF transactivating complex";"E3 ubiquitin ligases ubiquitinate target proteins";"Hedgehog 'on' state"
LHES006522-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
LHES007386-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
LHES004173-PA	4	Reactome: R-HSA-975144;MetaCyc: PWY-7511;Reactome: R-HSA-9020702;Reactome: R-HSA-937039	"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Protein ubiquitination";"Interleukin-1 signaling";"IRAK1 recruits IKK complex"
LHES010509-PA	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
LHES013494-PA	30	Reactome: R-HSA-6782135;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-2564830;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-167152;Reactome: R-HSA-73776;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-75955;Reactome: R-HSA-73762;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-427413;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-73863;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-5696395;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-73779	"Dual incision in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Cytosolic iron-sulfur cluster assembly";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Promoter Escape";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of Incision Complex in GG-NER";"mRNA Capping";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
LHES009553-PA	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
LHES001602-PA	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
LHES001331-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
LHES003746-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
LHES008233-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
LHES000364-PA	10	KEGG: 00030+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00680+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-7385;KEGG: 00052+2.7.1.11	"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Galactose metabolism"
LHES012927-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES009334-PA	16	Reactome: R-HSA-8934593;Reactome: R-HSA-9018519;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-8986944;Reactome: R-HSA-8853884;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-9029569;Reactome: R-HSA-2559585;Reactome: R-HSA-8948700;Reactome: R-HSA-8936459	"Regulation of RUNX1 Expression and Activity";"Estrogen-dependent gene expression";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by MECP2";"Transcriptional Regulation by VENTX";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oncogene Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
LHES017322-PA	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
LHES002190-PA	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090	"Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures"
LHES005956-PA	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
LHES004663-PA	7	MetaCyc: PWY-5941;KEGG: 00500+2.4.1.25;Reactome: R-HSA-70221;MetaCyc: PWY-6724;Reactome: R-HSA-6798695;MetaCyc: PWY-6737;MetaCyc: PWY-7238	"Glycogen degradation II";"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)";"Starch degradation II";"Neutrophil degranulation";"Starch degradation V";"Sucrose biosynthesis II"
LHES010774-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
LHES008969-PA	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
LHES015986-PA	5	Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-163765	"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression"
LHES012171-PA	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
LHES014324-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
LHES009972-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
LHES006612-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
LHES008979-PA	8	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"T cell receptor signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection"
LHES009954-PA	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
LHES007097-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
LHES016794-PA	1	Reactome: R-HSA-71336	"Pentose phosphate pathway"
LHES003858-PA	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
LHES016871-PA	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
LHES013398-PA	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
LHES005050-PA	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
LHES009848-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
LHES000885-PA	1	Reactome: R-HSA-390651	"Dopamine receptors"
LHES005879-PA	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
LHES006463-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
LHES007950-PA	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
LHES004109-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
LHES010271-PA	1	Reactome: R-HSA-73621	"Pyrimidine catabolism"
LHES003897-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
LHES009015-PA	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
LHES015774-PA	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
LHES000525-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
LHES009251-PA	13	Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit"
LHES005827-PA	4	Reactome: R-HSA-73817;KEGG: 00250+6.3.4.4;MetaCyc: PWY-7219;KEGG: 00230+6.3.4.4	"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
LHES010222-PA	1	Reactome: R-HSA-611105	"Respiratory electron transport"
LHES013731-PA	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
LHES004958-PA	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
LHES013115-PA	4	Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
LHES014844-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
LHES014529-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
LHES000979-PA	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
LHES003670-PA	7	Reactome: R-HSA-9018519;Reactome: R-HSA-2500257;Reactome: R-HSA-3108214;Reactome: R-HSA-2467813;Reactome: R-HSA-1221632;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052	"Estrogen-dependent gene expression";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Separation of Sister Chromatids";"Meiotic synapsis";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion"
LHES004979-PA	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
LHES011150-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
LHES002155-PA	5	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network"
LHES001365-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
LHES012891-PA	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
LHES003852-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
LHES009211-PA	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
LHES004815-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
LHES005614-PA	1	Reactome: R-HSA-5689603	"UCH proteinases"
LHES004153-PA	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
LHES008403-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
LHES007677-PA	17	Reactome: R-HSA-5358606;Reactome: R-HSA-174437;Reactome: R-HSA-174417;Reactome: R-HSA-5651801;Reactome: R-HSA-5358565;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-69183;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-174414;Reactome: R-HSA-69166;Reactome: R-HSA-174411	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Removal of the Flap Intermediate from the C-strand";"Telomere C-strand (Lagging Strand) Synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Processive synthesis on the C-strand of the telomere";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere"
LHES009711-PA	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
LHES000937-PA	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
LHES005271-PA	5	Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-5250924	"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression"
LHES003501-PA	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
LHES015062-PA	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
LHES011815-PA	3	MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33	"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
LHES003489-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
LHES007887-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
LHES004514-PA	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
LHES015899-PA	14	MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7724;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7035	"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis"
LHES003420-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
LHES007414-PA	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
LHES014855-PA	56	Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-69601;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5687128;Reactome: R-HSA-69481;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-187577;Reactome: R-HSA-2871837;Reactome: R-HSA-69017;Reactome: R-HSA-8854050;Reactome: R-HSA-450408;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-174154	"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"ABC-family proteins mediated transport";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"SCF(Skp2)-mediated degradation of p27/p21";"FCERI mediated NF-kB activation";"CDK-mediated phosphorylation and removal of Cdc6";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdc20 mediated degradation of Securin"
LHES009120-PA	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
LHES014469-PA	5	Reactome: R-HSA-983168;Reactome: R-HSA-977225;Reactome: R-HSA-9646399;Reactome: R-HSA-5689877;Reactome: R-HSA-5205685	"Antigen processing: Ubiquitination & Proteasome degradation";"Amyloid fiber formation";"Aggrephagy";"Josephin domain DUBs";"Pink/Parkin Mediated Mitophagy"
LHES016989-PA	27	Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-180910	"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"Vpr-mediated nuclear import of PICs"
LHES003170-PA	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
LHES004307-PA	8	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Activation of RAC1";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway"
LHES004372-PA	2	Reactome: R-HSA-5689880;MetaCyc: PWY-7511	"Ub-specific processing proteases";"Protein ubiquitination"
LHES010915-PA	4	Reactome: R-HSA-1660662;MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119	"Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)"
LHES011654-PA	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
LHES006670-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
LHES002658-PA	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
LHES013248-PA	12	Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-6804756;Reactome: R-HSA-75955	"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Elongation"
LHES011000-PA	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
LHES016489-PA	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
LHES003733-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
LHES014170-PA	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
LHES004968-PA	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
LHES009272-PA	5	MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-8013	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III"
LHES005407-PA	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
LHES006817-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
LHES014423-PA	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
LHES001176-PA	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
LHES012239-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
LHES015919-PA	6	MetaCyc: PWY-6737;MetaCyc: PWY-7238;MetaCyc: PWY-6731;Reactome: R-HSA-70221;KEGG: 00500+2.4.1.1;MetaCyc: PWY-5941	"Starch degradation V";"Sucrose biosynthesis II";"Starch degradation III";"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism";"Glycogen degradation II"
LHES001965-PA	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
LHES004539-PA	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
LHES007970-PA	6	Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450604	"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA"
LHES013733-PA	1	Reactome: R-HSA-5676934	"Protein repair"
LHES012811-PA	14	MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;Reactome: R-HSA-75876	"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs"
LHES007982-PA	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
LHES016514-PA	1	Reactome: R-HSA-5685939	"HDR through MMEJ (alt-NHEJ)"
LHES012721-PA	5	Reactome: R-HSA-450321;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors"
LHES010659-PA	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
LHES006392-PA	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
LHES000516-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
LHES006530-PA	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
LHES000526-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
LHES003127-PA	4	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;Reactome: R-HSA-196843;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Vitamin B2 (riboflavin) metabolism";"Phosphate acquisition"
LHES000365-PA	10	KEGG: 00052+2.7.1.11;MetaCyc: PWY-7385;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00680+2.7.1.11;KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11	"Galactose metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway"
LHES014437-PA	3	KEGG: 00860+1.3.3.4;Reactome: R-HSA-189451;MetaCyc: PWY-7159	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
LHES002457-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
LHES007842-PA	5	Reactome: R-HSA-196757;MetaCyc: PWY-3841;MetaCyc: PWY-6614;KEGG: 00670+1.5.1.3;KEGG: 00790+1.5.1.3	"Metabolism of folate and pterines";"Folate transformations II (plants)";"Tetrahydrofolate biosynthesis";"One carbon pool by folate";"Folate biosynthesis"
LHES002556-PA	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
LHES010264-PA	20	Reactome: R-HSA-5651801;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-69091;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121	"PCNA-Dependent Long Patch Base Excision Repair";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Polymerase switching";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI"
LHES009080-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
LHES015751-PA	7	Reactome: R-HSA-418594;Reactome: R-HSA-8957275;Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-381426;Reactome: R-HSA-140837;Reactome: R-HSA-114608	"G alpha (i) signalling events";"Post-translational protein phosphorylation";"Peptide ligand-binding receptors";"G alpha (q) signalling events";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Intrinsic Pathway of Fibrin Clot Formation";"Platelet degranulation"
LHES004843-PA	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
LHES014244-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
LHES016641-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
LHES005766-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
LHES016631-PA	1	Reactome: R-HSA-9640463	"Wax biosynthesis"
LHES010398-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
LHES008059-PA	11	Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-3214858;Reactome: R-HSA-6804114;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-9018519;Reactome: R-HSA-1368082;Reactome: R-HSA-381340	"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"RMTs methylate histone arginines";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"Estrogen-dependent gene expression";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
LHES006628-PA	7	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
LHES004263-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
LHES016192-PA	2	Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2	"Glycine degradation";"Glycine, serine and threonine metabolism"
LHES014700-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES017038-PA	11	Reactome: R-HSA-4043916;MetaCyc: PWY-7456;MetaCyc: PWY-6992;MetaCyc: PWY-5659;MetaCyc: PWY-882;MetaCyc: PWY-7586;KEGG: 00520+5.3.1.8;Reactome: R-HSA-446205;MetaCyc: PWY-3861;MetaCyc: PWY-3881;KEGG: 00051+5.3.1.8	"Defective MPI causes MPI-CDG (CDG-1b)";"Beta-(1,4)-mannan degradation";"1,5-anhydrofructose degradation";"GDP-mannose biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"Mannitol degradation II";"Mannitol biosynthesis";"Fructose and mannose metabolism"
LHES015337-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
LHES006360-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
LHES013005-PA	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
LHES010293-PA	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
LHES003113-PA	3	Reactome: R-HSA-400206;Reactome: R-HSA-427413;Reactome: R-HSA-8936459	"Regulation of lipid metabolism by PPARalpha";"NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
LHES004602-PA	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
LHES012711-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
LHES009129-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
LHES004140-PA	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
LHES012550-PA	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
LHES003908-PA	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
LHES008637-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
LHES006292-PA	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
LHES016080-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
LHES003153-PA	10	Reactome: R-HSA-5693579;Reactome: R-HSA-3108214;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607	"Homologous DNA Pairing and Strand Exchange";"SUMOylation of DNA damage response and repair proteins";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends"
LHES001297-PA	1	Reactome: R-HSA-156590	"Glutathione conjugation"
LHES015080-PA	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
LHES014174-PA	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
LHES001508-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
LHES015901-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
LHES009197-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
LHES002000-PA	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
LHES016323-PA	1	Reactome: R-HSA-525793	"Myogenesis"
LHES005255-PA	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
LHES000844-PA	31	MetaCyc: PWY-7858;MetaCyc: PWY-6799;MetaCyc: PWY-8047;MetaCyc: PWY-6113;MetaCyc: PWY-8012;MetaCyc: PWY-7723;Reactome: R-HSA-2426168;MetaCyc: PWY-8049;MetaCyc: PWY-5994;Reactome: R-HSA-9029558;MetaCyc: PWY-5989;MetaCyc: PWY-5367;MetaCyc: PWY-6282;MetaCyc: PWY-6519;MetaCyc: PWY-7388;Reactome: R-HSA-75105;MetaCyc: PWY-5142;MetaCyc: PWY-7746;MetaCyc: PWY-5973;MetaCyc: PWY-5971;Reactome: R-HSA-199220;Reactome: R-HSA-163765;MetaCyc: PWY-7664;MetaCyc: PWYG-321;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7663;MetaCyc: PWY-5966-1;MetaCyc: PWY-5366;MetaCyc: PWY-5147;MetaCyc: PWY-4381;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41	"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis initiation (plant mitochondria)";"Bryostatin biosynthesis";"Superpathway of mycolate biosynthesis";"Mupirocin biosynthesis";"Bacterial bioluminescence";"Activation of gene expression by SREBF (SREBP)";"Pederin biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Stearate biosynthesis II (bacteria and plants)";"Petroselinate biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"8-amino-7-oxononanoate biosynthesis I";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acyl-CoA biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Mycobacterial sulfolipid biosynthesis";"Cis-vaccenate biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression";"Oleate biosynthesis IV (anaerobic)";"";"Fatty acid biosynthesis";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Biotin metabolism"
LHES007962-PA	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
LHES015583-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
LHES003308-PA	5	Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-3249367;Reactome: R-HSA-1834941;Reactome: R-HSA-3134975	"IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"STAT6-mediated induction of chemokines";"STING mediated induction of host immune responses";"Regulation of innate immune responses to cytosolic DNA"
LHES005609-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
LHES001546-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
LHES004071-PA	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
LHES001309-PA	11	Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167200	"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
LHES009810-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
LHES003361-PA	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
LHES017039-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
LHES010864-PA	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
LHES003377-PA	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
LHES004322-PA	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
LHES004662-PA	7	MetaCyc: PWY-6724;MetaCyc: PWY-6737;MetaCyc: PWY-7238;Reactome: R-HSA-6798695;KEGG: 00500+2.4.1.25;MetaCyc: PWY-5941;Reactome: R-HSA-70221	"Starch degradation II";"Starch degradation V";"Sucrose biosynthesis II";"Neutrophil degranulation";"Starch and sucrose metabolism";"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)"
LHES013069-PA	8	Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-68949	"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin"
LHES005650-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
LHES009634-PA	5	MetaCyc: PWY-7922;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis"
LHES012064-PA	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
LHES009966-PA	5	Reactome: R-HSA-165181;Reactome: R-HSA-380972;Reactome: R-HSA-8854214;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897	"Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK";"TBC/RABGAPs";"Macroautophagy";"TP53 Regulates Metabolic Genes"
LHES007600-PA	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
LHES007076-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
LHES010501-PA	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
LHES016792-PA	8	Reactome: R-HSA-8953750;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-6803207;Reactome: R-HSA-6798695	"Transcriptional Regulation by E2F6";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Neutrophil degranulation"
LHES004335-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
LHES016820-PA	33	Reactome: R-HSA-3108214;Reactome: R-HSA-2467813;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-141444;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-68877;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-5663220;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-9648025;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-180910	"SUMOylation of DNA damage response and repair proteins";"Separation of Sister Chromatids";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"Mitotic Prometaphase";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"RHO GTPases Activate Formins";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"EML4 and NUDC in mitotic spindle formation";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs"
LHES006741-PA	1	Reactome: R-HSA-74217	"Purine salvage"
LHES006668-PA	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
LHES001368-PA	4	Reactome: R-HSA-3359475;Reactome: R-HSA-196741;Reactome: R-HSA-71032;Reactome: R-HSA-3359478	"Defective MMAA causes methylmalonic aciduria type cblA";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Propionyl-CoA catabolism";"Defective MUT causes methylmalonic aciduria mut type"
LHES009330-PA	8	Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Activation of RAC1";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway"
LHES003309-PA	42	Reactome: R-HSA-201722;Reactome: R-HSA-110329;Reactome: R-HSA-2559582;Reactome: R-HSA-5250924;Reactome: R-HSA-212300;Reactome: R-HSA-110330;Reactome: R-HSA-8936459;Reactome: R-HSA-9609690;Reactome: R-HSA-606279;Reactome: R-HSA-73772;Reactome: R-HSA-9616222;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-2559580;Reactome: R-HSA-2559586;Reactome: R-HSA-3214841;Reactome: R-HSA-1912408;Reactome: R-HSA-912446;Reactome: R-HSA-2299718;Reactome: R-HSA-73728;Reactome: R-HSA-110328;Reactome: R-HSA-4551638;Reactome: R-HSA-5693607;Reactome: R-HSA-5578749;Reactome: R-HSA-3214815;Reactome: R-HSA-171306;Reactome: R-HSA-5334118;Reactome: R-HSA-5693565;Reactome: R-HSA-5617472;Reactome: R-HSA-427389;Reactome: R-HSA-1221632;Reactome: R-HSA-8939236;Reactome: R-HSA-977225;Reactome: R-HSA-9018519;Reactome: R-HSA-9610379;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-3214842;Reactome: R-HSA-3214858;Reactome: R-HSA-5625886;Reactome: R-HSA-110331;Reactome: R-HSA-3214847	"Formation of the beta-catenin:TCF transactivating complex";"Cleavage of the damaged pyrimidine";"Senescence-Associated Secretory Phenotype (SASP)";"B-WICH complex positively regulates rRNA expression";"PRC2 methylates histones and DNA";"Recognition and association of DNA glycosylase with site containing an affected purine";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HCMV Early Events";"Deposition of new CENPA-containing nucleosomes at the centromere";"RNA Polymerase I Promoter Escape";"Transcriptional regulation of granulopoiesis";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Oxidative Stress Induced Senescence";"DNA Damage/Telomere Stress Induced Senescence";"PKMTs methylate histone lysines";"Pre-NOTCH Transcription and Translation";"Meiotic recombination";"Condensation of Prophase Chromosomes";"RNA Polymerase I Promoter Opening";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of chromatin organization proteins";"Processing of DNA double-strand break ends";"Transcriptional regulation by small RNAs";"HDACs deacetylate histones";"Packaging Of Telomere Ends";"DNA methylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Meiotic synapsis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Amyloid fiber formation";"Estrogen-dependent gene expression";"HCMV Late Events";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"HDMs demethylate histones";"RMTs methylate histone arginines";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Cleavage of the damaged purine";"HATs acetylate histones"
LHES011406-PA	8	MetaCyc: PWY-6309;KEGG: 00380+3.5.1.9;MetaCyc: PWY-7717;MetaCyc: PWY-7765;MetaCyc: PWY-7733;MetaCyc: PWY-5651;MetaCyc: PWY-7734;KEGG: 00630+3.5.1.9	"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"3-hydroxyquinaldate biosynthesis";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Quinoxaline-2-carboxylate biosynthesis";"Glyoxylate and dicarboxylate metabolism"
LHES002961-PA	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
LHES014147-PA	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
LHES000152-PA	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
LHES007923-PA	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
LHES015005-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
LHES006993-PA	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
LHES011523-PA	1	Reactome: R-HSA-3000178	"ECM proteoglycans"
LHES011925-PA	56	Reactome: R-HSA-2871837;Reactome: R-HSA-187577;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-69017;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-8939236;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-5687128;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-1236978;Reactome: R-HSA-8852276;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813	"FCERI mediated NF-kB activation";"SCF(Skp2)-mediated degradation of p27/p21";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"MAPK6/MAPK4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"ABC-family proteins mediated transport";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"Neddylation";"Cross-presentation of soluble exogenous antigens (endosomes)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids"
LHES013286-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
LHES009137-PA	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
LHES006768-PA	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
LHES003080-PA	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
LHES001469-PA	1	Reactome: R-HSA-611105	"Respiratory electron transport"
LHES016248-PA	6	Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-6798695;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Neutrophil degranulation";"Ion channel transport";"Transferrin endocytosis and recycling"
LHES000425-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
LHES013016-PA	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
LHES007922-PA	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
LHES016843-PA	5	Reactome: R-HSA-427413;Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300;Reactome: R-HSA-4655427	"NoRC negatively regulates rRNA expression";"DNA methylation";"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins"
LHES001966-PA	6	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Neutrophil degranulation"
LHES009448-PA	16	Reactome: R-HSA-194840;Reactome: R-HSA-912631;Reactome: R-HSA-512988;Reactome: R-HSA-6811558;Reactome: R-HSA-114604;Reactome: R-HSA-389357;Reactome: R-HSA-1433557;Reactome: R-HSA-912526;Reactome: R-HSA-416476;Reactome: R-HSA-388841;Reactome: R-HSA-8853659;Reactome: R-HSA-1660499;Reactome: R-HSA-2219530;Reactome: R-HSA-9009391;Reactome: R-HSA-1257604;Reactome: R-HSA-1266695	"Rho GTPase cycle";"Regulation of signaling by CBL";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"GPVI-mediated activation cascade";"CD28 dependent PI3K/Akt signaling";"Signaling by SCF-KIT";"Interleukin receptor SHC signaling";"G alpha (q) signalling events";"Costimulation by the CD28 family";"RET signaling";"Synthesis of PIPs at the plasma membrane";"Constitutive Signaling by Aberrant PI3K in Cancer";"Extra-nuclear estrogen signaling";"PIP3 activates AKT signaling";"Interleukin-7 signaling"
LHES015150-PA	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
LHES005389-PA	2	KEGG: 00900+2.1.1.100;Reactome: R-HSA-163841	"Terpenoid backbone biosynthesis";"Gamma carboxylation, hypusine formation and arylsulfatase activation"
LHES006597-PA	10	Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-9018519	"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Estrogen-dependent gene expression"
LHES000318-PA	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
LHES004254-PA	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
LHES005162-PA	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
LHES010832-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
LHES012422-PA	1	Reactome: R-HSA-8951664	"Neddylation"
LHES010010-PA	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
LHES006635-PA	5	MetaCyc: PWY-7159;MetaCyc: PWY-5531;MetaCyc: PWY-7766;KEGG: 00860+4.1.1.37;Reactome: R-HSA-189451	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Heme b biosynthesis IV (Gram-positive bacteria)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
LHES001984-PA	9	Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-73779	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
LHES015947-PA	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
LHES002542-PA	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
LHES004408-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
LHES003565-PA	4	Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols"
LHES011006-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
LHES012691-PA	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5689877;Reactome: R-HSA-5696395	"DNA Damage Recognition in GG-NER";"Josephin domain DUBs";"Formation of Incision Complex in GG-NER"
LHES004444-PA	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
LHES015063-PA	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
LHES002127-PA	1	Reactome: R-HSA-8951664	"Neddylation"
LHES010014-PA	1	Reactome: R-HSA-186797	"Signaling by PDGF"
LHES013871-PA	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
LHES006270-PA	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
LHES008943-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES008291-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
LHES007977-PA	4	Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16	"Metabolism of polyamines";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism"
LHES009509-PA	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
LHES009504-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
LHES012715-PA	6	MetaCyc: PWY-8004;MetaCyc: PWY-5514;MetaCyc: PWY-6906;KEGG: 00030+3.1.1.31;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6	"Entner-Doudoroff pathway I";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation";"Pentose phosphate pathway";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
LHES008258-PA	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
LHES013473-PA	6	Reactome: R-HSA-70221;KEGG: 00500+2.4.1.1;MetaCyc: PWY-5941;MetaCyc: PWY-6737;MetaCyc: PWY-7238;MetaCyc: PWY-6731	"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism";"Glycogen degradation II";"Starch degradation V";"Sucrose biosynthesis II";"Starch degradation III"
LHES012095-PA	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
LHES001754-PA	8	Reactome: R-HSA-975957;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway"
LHES004438-PA	6	Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176187	"Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress"
LHES000674-PA	1	Reactome: R-HSA-8951664	"Neddylation"
LHES002964-PA	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
LHES012980-PA	13	Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-6791226	"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol"
LHES007844-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
LHES001477-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
LHES008966-PA	3	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
LHES017044-PA	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
LHES011572-PA	7	Reactome: R-HSA-416476;Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-8957275;Reactome: R-HSA-114608;Reactome: R-HSA-140837;Reactome: R-HSA-381426	"G alpha (q) signalling events";"Peptide ligand-binding receptors";"G alpha (i) signalling events";"Post-translational protein phosphorylation";"Platelet degranulation";"Intrinsic Pathway of Fibrin Clot Formation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
LHES011334-PA	6	Reactome: R-HSA-8949613;Reactome: R-HSA-163210;Reactome: R-HSA-1268020;MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2	"Cristae formation";"Formation of ATP by chemiosmotic coupling";"Mitochondrial protein import";"ATP biosynthesis";"Photosynthesis";"Oxidative phosphorylation"
LHES007266-PA	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
LHES005575-PA	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
LHES005370-PA	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
LHES010009-PA	7	MetaCyc: PWY-2941;MetaCyc: PWY-8088;MetaCyc: PWY-2942;KEGG: 00261+4.3.3.7;KEGG: 00300+4.3.3.7;MetaCyc: PWY-5097;Reactome: R-HSA-389661	"L-lysine biosynthesis II";"Dipicolinate biosynthesis";"L-lysine biosynthesis III";"Monobactam biosynthesis";"Lysine biosynthesis";"L-lysine biosynthesis VI";"Glyoxylate metabolism and glycine degradation"
LHES005549-PA	8	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human papillomavirus infection";"mTOR signaling pathway"
LHES001000-PA	1	Reactome: R-HSA-5689603	"UCH proteinases"
LHES003738-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
LHES013135-PA	13	Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation"
LHES008096-PA	9	KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822	"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)"
LHES000537-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
LHES003486-PA	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
LHES012359-PA	7	MetaCyc: PWY-8043;Reactome: R-HSA-174403;MetaCyc: PWY-6840;MetaCyc: PWY-7255;Reactome: R-HSA-5578999;KEGG: 00270+6.3.2.2;KEGG: 00480+6.3.2.2	"Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Homoglutathione biosynthesis";"Ergothioneine biosynthesis I (bacteria)";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Cysteine and methionine metabolism";"Glutathione metabolism"
LHES006804-PA	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
LHES001352-PA	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
LHES008353-PA	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
LHES014361-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
LHES001823-PA	5	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-3214815	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HDACs deacetylate histones"
LHES004437-PA	2	Reactome: R-HSA-194840;Reactome: R-HSA-8876198	"Rho GTPase cycle";"RAB GEFs exchange GTP for GDP on RABs"
LHES000189-PA	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
LHES013191-PA	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
LHES003124-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES012028-PA	5	KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5667;MetaCyc: PWY-5981	"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III"
LHES016587-PA	4	KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202	"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines"
LHES006261-PA	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
LHES004162-PA	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
LHES010430-PA	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
LHES007921-PA	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
LHES003122-PA	1	Reactome: R-HSA-525793	"Myogenesis"
LHES000191-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
LHES012384-PA	5	Reactome: R-HSA-9029558;Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-2426168	"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)"
LHES005023-PA	5	Reactome: R-HSA-71336;KEGG: 00030+4.1.2.4;MetaCyc: PWY-8060;MetaCyc: PWY-7180;Reactome: R-HSA-6798695	"Pentose phosphate pathway";"Pentose phosphate pathway";"2-deoxy-D-ribose degradation I";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Neutrophil degranulation"
LHES007063-PA	6	KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis"
LHES000728-PA	4	Reactome: R-HSA-6814122;Reactome: R-HSA-112043;Reactome: R-HSA-418594;Reactome: R-HSA-202040	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"PLC beta mediated events";"G alpha (i) signalling events";"G-protein activation"
LHES016172-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
LHES009991-PA	10	Reactome: R-HSA-2142789;MetaCyc: PWY-5892;MetaCyc: PWY-5849;MetaCyc: PWY-7996;MetaCyc: PWY-5844;MetaCyc: PWY-5895;MetaCyc: PWY-5839;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5890;MetaCyc: PWY-5891	"Ubiquinol biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-9 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-7 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-11 biosynthesis"
LHES004045-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
LHES009569-PA	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
LHES008819-PA	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890	"T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling"
LHES002928-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
LHES004341-PA	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
LHES015212-PA	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
LHES000423-PA	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
LHES007730-PA	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
LHES011143-PA	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
LHES013341-PA	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
LHES006290-PA	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
LHES013825-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
LHES017270-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
LHES008141-PA	1	Reactome: R-HSA-611105	"Respiratory electron transport"
LHES003015-PA	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
LHES014627-PA	1	Reactome: R-HSA-200425	"Carnitine metabolism"
LHES001824-PA	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
LHES012731-PA	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
LHES012127-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES010663-PA	3	Reactome: R-HSA-72163;Reactome: R-HSA-5250924;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway"
LHES017020-PA	56	Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-8939236;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-5362768;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895	"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Neddylation";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"ABC-family proteins mediated transport";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis"
LHES012501-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-1268020	"Respiratory electron transport";"Mitochondrial protein import"
LHES002102-PA	3	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.4;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
LHES000556-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
LHES005447-PA	3	KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317	"Glycolysis / Gluconeogenesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)"
LHES013898-PA	13	KEGG: 00230+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7210;Reactome: R-HSA-499943;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7198;KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1	"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Drug metabolism - other enzymes";"Pyrimidine metabolism"
LHES011773-PA	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
LHES005384-PA	5	Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-427413	"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression"
LHES000981-PA	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
LHES009140-PA	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
LHES013271-PA	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
LHES002661-PA	1	Reactome: R-HSA-1483148	"Synthesis of PG"
LHES014446-PA	3	MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
LHES012466-PA	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
LHES009027-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES004521-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
LHES004863-PA	17	MetaCyc: PWY-1622;MetaCyc: PWY-5690;KEGG: 00270+1.1.1.37;KEGG: 00720+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-5392;MetaCyc: PWY-6728;KEGG: 00630+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-5913;MetaCyc: PWY-6969;MetaCyc: PWY-8086;KEGG: 00620+1.1.1.37;MetaCyc: PWY-561;KEGG: 00020+1.1.1.37	"Formaldehyde assimilation I (serine pathway)";"TCA cycle II (plants and fungi)";"Cysteine and methionine metabolism";"Carbon fixation pathways in prokaryotes";"Methane metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reductive TCA cycle II";"Methylaspartate cycle";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation in photosynthetic organisms";"Anaerobic energy metabolism (invertebrates, cytosol)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)"
LHES002503-PA	7	Reactome: R-HSA-156711;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"Polo-like kinase mediated events";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
LHES011415-PA	5	Reactome: R-HSA-2022090;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-1679131;Reactome: R-HSA-1442490	"Assembly of collagen fibrils and other multimeric structures";"Neutrophil degranulation";"MHC class II antigen presentation";"Trafficking and processing of endosomal TLR";"Collagen degradation"
LHES009784-PA	4	Reactome: R-HSA-71032;Reactome: R-HSA-3359478;Reactome: R-HSA-3359475;Reactome: R-HSA-196741	"Propionyl-CoA catabolism";"Defective MUT causes methylmalonic aciduria mut type";"Defective MMAA causes methylmalonic aciduria type cblA";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
LHES000480-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
LHES005374-PA	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
LHES000795-PA	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
LHES014789-PA	14	MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-8051;Reactome: R-HSA-1483191;MetaCyc: PWY-8055;MetaCyc: PWY-6453;KEGG: 00600+3.1.3.4;KEGG: 00565+3.1.3.4;Reactome: R-HSA-4419969;KEGG: 00564+3.1.3.4;Reactome: R-HSA-75109;MetaCyc: PWY-8052;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483213	"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Synthesis of PC";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Sphingolipid metabolism";"Ether lipid metabolism";"Depolymerisation of the Nuclear Lamina";"Glycerophospholipid metabolism";"Triglyceride biosynthesis";"2-arachidonoylglycerol biosynthesis";"Glycerolipid metabolism";"Synthesis of PE"
LHES002956-PA	16	MetaCyc: PWY-2221;KEGG: 00010+4.2.1.11;KEGG: 00680+4.2.1.11;MetaCyc: PWY-8004;Reactome: R-HSA-70171;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-7218;MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-1622;Reactome: R-HSA-70263;MetaCyc: PWY-6886;MetaCyc: PWY-6142;MetaCyc: PWY-7124;MetaCyc: PWY-5723	"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Entner-Doudoroff pathway I";"Glycolysis";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Formaldehyde assimilation I (serine pathway)";"Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Ethylene biosynthesis V (engineered)";"Rubisco shunt"
LHES003605-PA	8	Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-380972	"Neutrophil degranulation";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Macroautophagy";"mTOR signalling";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK"
LHES009224-PA	1	Reactome: R-HSA-110357	"Displacement of DNA glycosylase by APEX1"
LHES007630-PA	5	Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-5675221;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955	"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of MAPK pathway";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
LHES010523-PA	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
LHES000959-PA	4	KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;MetaCyc: PWY-5067;MetaCyc: PWY-7900	"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)"
LHES003959-PA	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
LHES016597-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
LHES010992-PA	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
LHES004798-PA	3	Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880	"TCF dependent signaling in response to WNT";"Degradation of AXIN";"Ub-specific processing proteases"
LHES017071-PA	15	MetaCyc: PWY-8004;MetaCyc: PWY-6886;MetaCyc: PWY-5723;MetaCyc: PWY-6142;Reactome: R-HSA-70171;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6901;KEGG: 00230+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-7218;MetaCyc: PWY-7383;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-2221	"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Rubisco shunt";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Purine metabolism";"Glycolysis IV (plant cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Entner-Doudoroff pathway III (semi-phosphorylative)"
LHES012790-PA	2	Reactome: R-HSA-2206307;Reactome: R-HSA-2024096	"MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation"
LHES007434-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
LHES014283-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
LHES010716-PA	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
LHES009348-PA	4	KEGG: 00600+3.2.1.18;KEGG: 00511+3.2.1.18;Reactome: R-HSA-4085001;Reactome: R-HSA-1660662	"Sphingolipid metabolism";"Other glycan degradation";"Sialic acid metabolism";"Glycosphingolipid metabolism"
LHES012177-PA	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
LHES000403-PA	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
LHES010118-PA	4	Reactome: R-HSA-6799198;Reactome: R-HSA-975138;Reactome: R-HSA-166058;Reactome: R-HSA-975871	"Complex I biogenesis";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 cascade initiated on plasma membrane"
LHES008510-PA	5	Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
LHES007260-PA	11	Reactome: R-HSA-174430;Reactome: R-HSA-5651801;Reactome: R-HSA-68952;Reactome: R-HSA-6782135;Reactome: R-HSA-68962;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942	"Telomere C-strand synthesis initiation";"PCNA-Dependent Long Patch Base Excision Repair";"DNA replication initiation";"Dual incision in TC-NER";"Activation of the pre-replicative complex";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)"
LHES001755-PA	8	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway"
LHES016858-PA	27	Reactome: R-HSA-4615885;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-168333	"SUMOylation of DNA replication proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery"
LHES005111-PA	6	Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827	"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression"
LHES006947-PA	10	Reactome: R-HSA-2160916;Reactome: R-HSA-6798695;Reactome: R-HSA-2206292;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00604+3.2.1.23	"Hyaluronan uptake and degradation";"Neutrophil degranulation";"MPS VII - Sly syndrome";"Sphingolipid metabolism";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Glycosaminoglycan degradation";"HS-GAG degradation";"Glycosphingolipid biosynthesis - ganglio series"
LHES011413-PA	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
LHES014239-PA	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
LHES011073-PA	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
LHES011223-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
LHES001218-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
LHES002798-PA	16	Reactome: R-HSA-176412;Reactome: R-HSA-2559582;Reactome: R-HSA-8853884;Reactome: R-HSA-141430;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-176409;Reactome: R-HSA-174048;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-176407;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-174178	"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Cyclin B";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
LHES008715-PA	4	Reactome: R-HSA-379726;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379716	"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
LHES001251-PA	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
LHES010754-PA	4	Reactome: R-HSA-9615710;Reactome: R-HSA-9613829;Reactome: R-HSA-3899300;Reactome: R-HSA-9646399	"Late endosomal microautophagy";"Chaperone Mediated Autophagy";"SUMOylation of transcription cofactors";"Aggrephagy"
LHES014419-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
LHES001123-PA	1	Reactome: R-HSA-525793	"Myogenesis"
LHES004876-PA	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
LHES014325-PA	1	Reactome: R-HSA-611105	"Respiratory electron transport"
LHES000045-PA	1	Reactome: R-HSA-977443	"GABA receptor activation"
LHES009390-PA	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
LHES017049-PA	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
LHES007416-PA	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
LHES001340-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
LHES009985-PA	2	Reactome: R-HSA-8854214;Reactome: R-HSA-977225	"TBC/RABGAPs";"Amyloid fiber formation"
LHES012203-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
LHES007324-PA	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
LHES015769-PA	5	KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979;MetaCyc: PWY-7922	"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)"
LHES005372-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
LHES000706-PA	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
LHES003925-PA	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
LHES008263-PA	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
LHES004596-PA	3	MetaCyc: PWY-7799;MetaCyc: PWY-7800;Reactome: R-HSA-2514859	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade"
LHES004588-PA	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
LHES000258-PA	1	Reactome: R-HSA-8963889	"Assembly of active LPL and LIPC lipase complexes"
LHES014352-PA	4	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
LHES000194-PA	12	MetaCyc: PWY-5870;MetaCyc: PWY-5856;MetaCyc: PWY-5872;MetaCyc: PWY-6708;MetaCyc: PWY-5873;MetaCyc: PWY-7230;Reactome: R-HSA-2142789;MetaCyc: PWY-5855;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5871;MetaCyc: PWY-5857;MetaCyc: PWY-7233	"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)"
LHES001561-PA	4	Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
LHES000875-PA	11	KEGG: 05170+2.7.11.1;Reactome: R-HSA-8866654;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"E3 ubiquitin ligases ubiquitinate target proteins";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"Relaxin signaling pathway";"IRF3-mediated induction of type I IFN";"Human papillomavirus infection";"mTOR signaling pathway"
LHES004030-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
LHES000384-PA	1	Reactome: R-HSA-8951664	"Neddylation"
LHES010342-PA	3	MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
LHES000858-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
LHES015018-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
LHES012175-PA	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
LHES009235-PA	4	Reactome: R-HSA-432720;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6811440	"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network"
LHES017124-PA	1	KEGG: 00982+1.14.13.8	"Drug metabolism - cytochrome P450"
LHES005131-PA	3	Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51	"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation"
LHES005843-PA	1	Reactome: R-HSA-8951664	"Neddylation"
LHES015598-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
LHES000866-PA	2	KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668	"Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
LHES012599-PA	3	KEGG: 00260+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3	"Glycine, serine and threonine metabolism";"Serine biosynthesis";"Methane metabolism"
LHES001373-PA	5	Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68867	"Activation of ATR in response to replication stress";"Unwinding of DNA";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex"
LHES008829-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
LHES006277-PA	8	MetaCyc: PWY-7733;MetaCyc: PWY-5651;MetaCyc: PWY-7734;KEGG: 00630+3.5.1.9;MetaCyc: PWY-6309;KEGG: 00380+3.5.1.9;MetaCyc: PWY-7717;MetaCyc: PWY-7765	"3-hydroxyquinaldate biosynthesis";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Quinoxaline-2-carboxylate biosynthesis";"Glyoxylate and dicarboxylate metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"3-hydroxy-4-methyl-anthranilate biosynthesis II"
LHES014320-PA	1	Reactome: R-HSA-5617833	"Cilium Assembly"
LHES001916-PA	56	Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-1236978;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-187577;Reactome: R-HSA-2871837;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5687128;Reactome: R-HSA-69481;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880	"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cross-presentation of soluble exogenous antigens (endosomes)";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"ABC-family proteins mediated transport";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"ER-Phagosome pathway";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"SCF(Skp2)-mediated degradation of p27/p21";"FCERI mediated NF-kB activation";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases"
LHES007224-PA	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
LHES014338-PA	1	Reactome: R-HSA-400253	"Circadian Clock"
LHES008847-PA	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
LHES002823-PA	1	Reactome: R-HSA-163841	"Gamma carboxylation, hypusine formation and arylsulfatase activation"
LHES007319-PA	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
LHES007661-PA	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
LHES009898-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
LHES015081-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
LHES003009-PA	3	Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311	"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance"
LHES008355-PA	9	Reactome: R-HSA-112043;MetaCyc: PWY-7039;MetaCyc: PWY-6351;MetaCyc: PWY-6367;MetaCyc: PWY-8052;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204	"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol"
LHES007180-PA	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
LHES005289-PA	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
LHES014241-PA	5	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-6784531	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"tRNA processing in the nucleus"
LHES002761-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
LHES009699-PA	13	Reactome: R-HSA-422356;Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-139853;Reactome: R-HSA-5218921;Reactome: R-HSA-5607763;Reactome: R-HSA-2871809;Reactome: R-HSA-114508;Reactome: R-HSA-4086398;Reactome: R-HSA-1489509;Reactome: R-HSA-5578775;Reactome: R-HSA-2029485;Reactome: R-HSA-381676	"Regulation of insulin secretion";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Elevation of cytosolic Ca2+ levels";"VEGFR2 mediated cell proliferation";"CLEC7A (Dectin-1) induces NFAT activation";"FCERI mediated Ca+2 mobilization";"Effects of PIP2 hydrolysis";"Ca2+ pathway";"DAG and IP3 signaling";"Ion homeostasis";"Role of phospholipids in phagocytosis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
LHES012117-PA	19	MetaCyc: PWY-7606;MetaCyc: PWY-7338;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7574;MetaCyc: PWY-7291;MetaCyc: PWY-7288;MetaCyc: PWY-7340;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7337;MetaCyc: PWY-7858;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-5136;MetaCyc: PWY-6837;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7007	"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(5Z)-dodecenoate biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoate metabolism";"Methyl ketone biosynthesis (engineered)"
LHES008539-PA	6	Reactome: R-HSA-8862803;MetaCyc: PWY-6854;Reactome: R-HSA-8950505;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Ethylene biosynthesis III (microbes)";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis"
LHES001317-PA	1	Reactome: R-HSA-8951664	"Neddylation"
LHES001770-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
LHES001369-PA	4	Reactome: R-HSA-196741;Reactome: R-HSA-3359475;Reactome: R-HSA-71032;Reactome: R-HSA-3359478	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMAA causes methylmalonic aciduria type cblA";"Propionyl-CoA catabolism";"Defective MUT causes methylmalonic aciduria mut type"
LHES006575-PA	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
LHES012870-PA	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
LHES011061-PA	2	Reactome: R-HSA-909733;Reactome: R-HSA-8983711	"Interferon alpha/beta signaling";"OAS antiviral response"
LHES009138-PA	2	Reactome: R-HSA-6798695;Reactome: R-HSA-964975	"Neutrophil degranulation";"Vitamins B6 activation to pyridoxal phosphate"
LHES016616-PA	13	Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9010553	"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs"
LHES002142-PA	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection"
LHES013795-PA	27	Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-159231;Reactome: R-HSA-168271	"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus"
LHES009705-PA	5	Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-190873;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis"
LHES014749-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
LHES003695-PA	6	Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-418592;Reactome: R-HSA-428930	"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor"
LHES002800-PA	2	Reactome: R-HSA-171319;Reactome: R-HSA-6790901	"Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol"
LHES005253-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
LHES015194-PA	1	Reactome: R-HSA-71384	"Ethanol oxidation"
LHES010847-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
LHES004727-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
LHES015273-PA	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
LHES005915-PA	4	Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437;Reactome: R-HSA-5689603	"HATs acetylate histones";"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases"
LHES013204-PA	1	Reactome: R-HSA-8964539	"Glutamate and glutamine metabolism"
LHES011142-PA	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
LHES006294-PA	5	Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-163765	"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression"
LHES006016-PA	1	Reactome: R-HSA-975578	"Reactions specific to the complex N-glycan synthesis pathway"
LHES017010-PA	3	MetaCyc: PWY-6780;MetaCyc: PWY-6759;MetaCyc: PWY-6785	"Hydrogen production VI";"Hydrogen production III";"Hydrogen production VIII"
LHES017343-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
LHES003203-PA	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
LHES008689-PA	2	Reactome: R-HSA-446193;Reactome: R-HSA-5633231	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)"
LHES010844-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
LHES008070-PA	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-8876198	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs"
LHES010164-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
LHES002916-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
LHES002711-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
LHES002051-PA	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
LHES006748-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
LHES015997-PA	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
LHES017331-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
LHES010560-PA	2	Reactome: R-HSA-139853;Reactome: R-HSA-418346	"Elevation of cytosolic Ca2+ levels";"Platelet homeostasis"
LHES002876-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
LHES014070-PA	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
LHES014235-PA	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
LHES005717-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
LHES007165-PA	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
LHES011682-PA	6	MetaCyc: PWY-922;MetaCyc: PWY-7391;KEGG: 00900+4.1.1.33;Reactome: R-HSA-2426168;Reactome: R-HSA-446199;Reactome: R-HSA-191273	"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Synthesis of Dolichyl-phosphate";"Cholesterol biosynthesis"
LHES013364-PA	5	Reactome: R-HSA-70921;KEGG: 00670+4.3.1.4+2.1.2.5;MetaCyc: PWY-5030;MetaCyc: PWY-5497;KEGG: 00340+2.1.2.5	"Histidine catabolism";"One carbon pool by folate";"L-histidine degradation III";"Purine nucleobases degradation II (anaerobic)";"Histidine metabolism"
LHES008579-PA	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
LHES012957-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
LHES003126-PA	11	Reactome: R-HSA-193692;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-2644606;Reactome: R-HSA-3928665;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-9013700	"Regulated proteolysis of p75NTR";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus"
LHES007818-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
LHES015622-PA	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
LHES000524-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
LHES016228-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
LHES009479-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES011676-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
LHES010439-PA	2	Reactome: R-HSA-416476;Reactome: R-HSA-389397	"G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors"
LHES008199-PA	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
LHES011971-PA	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
LHES011753-PA	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
LHES009265-PA	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
LHES014785-PA	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
LHES001392-PA	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
LHES003860-PA	11	Reactome: R-HSA-6807878;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-3371497;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2132295;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-6811436	"COPI-mediated anterograde transport";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"MHC class II antigen presentation";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"COPI-independent Golgi-to-ER retrograde traffic"
LHES001908-PA	27	Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-4551638	"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins"
LHES004978-PA	1	Reactome: R-HSA-8951664	"Neddylation"
LHES011602-PA	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
LHES007851-PA	1	Reactome: R-HSA-211981	"Xenobiotics"
LHES001060-PA	6	Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-429958	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease"
LHES002013-PA	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
LHES010470-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
LHES008768-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
LHES005455-PA	22	Reactome: R-HSA-5673000;Reactome: R-HSA-141444;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-389513;Reactome: R-HSA-5358749;Reactome: R-HSA-432142;Reactome: R-HSA-5467340;Reactome: R-HSA-5358747;Reactome: R-HSA-5675221;Reactome: R-HSA-68877;Reactome: R-HSA-5467337;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-6811558;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-4641262;Reactome: R-HSA-9648025	"RAF activation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"AXIN missense mutants destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Mitotic Prometaphase";"APC truncation mutants have impaired AXIN binding";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"EML4 and NUDC in mitotic spindle formation"
LHES015527-PA	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
LHES006247-PA	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
LHES013928-PA	4	KEGG: 00270+1.13.11.20;MetaCyc: PWY-5331;Reactome: R-HSA-1614558;KEGG: 00430+1.13.11.20	"Cysteine and methionine metabolism";"Taurine biosynthesis I";"Degradation of cysteine and homocysteine";"Taurine and hypotaurine metabolism"
LHES012061-PA	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
LHES003320-PA	1	Reactome: R-HSA-5683826	"Surfactant metabolism"
LHES009042-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
LHES003940-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES017315-PA	5	Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-174490	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"HCMV Late Events";"Membrane binding and targetting of GAG proteins"
LHES005651-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
LHES005087-PA	4	KEGG: 00590+5.3.99.3;Reactome: R-HSA-499943;Reactome: R-HSA-2162123;Reactome: R-HSA-6798695	"Arachidonic acid metabolism";"Interconversion of nucleotide di- and triphosphates";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Neutrophil degranulation"
LHES008493-PA	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
LHES009550-PA	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
LHES002258-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
LHES010133-PA	2	Reactome: R-HSA-375276;Reactome: R-HSA-418555	"Peptide ligand-binding receptors";"G alpha (s) signalling events"
LHES009865-PA	1	Reactome: R-HSA-3295583	"TRP channels"
LHES016050-PA	19	Reactome: R-HSA-9649948;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-5578775;Reactome: R-HSA-5576892;Reactome: R-HSA-111932;Reactome: R-HSA-936837	"Signaling downstream of RAS mutants";"HSF1-dependent transactivation";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Ion homeostasis";"Phase 0 - rapid depolarisation";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases"
LHES007908-PA	6	MetaCyc: PWY-5743;MetaCyc: PWY-4381;MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-6722;Reactome: R-HSA-196780	"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"Biotin transport and metabolism"
LHES015176-PA	4	KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219	"Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis"
LHES009788-PA	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
LHES016993-PA	14	Reactome: R-HSA-75876;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-6433	"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)"
LHES008432-PA	4	Reactome: R-HSA-5694530;Reactome: R-HSA-6798695;Reactome: R-HSA-204005;Reactome: R-HSA-2132295	"Cargo concentration in the ER";"Neutrophil degranulation";"COPII-mediated vesicle transport";"MHC class II antigen presentation"
LHES003942-PA	12	Reactome: R-HSA-5250924;Reactome: R-HSA-2894862;Reactome: R-HSA-1912408;Reactome: R-HSA-3214847;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-73762;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695	"B-WICH complex positively regulates rRNA expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"HATs acetylate histones";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"RNA Polymerase I Transcription Initiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription"
LHES016023-PA	1	Reactome: R-HSA-189451	"Heme biosynthesis"
LHES004822-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
LHES016499-PA	1	Reactome: R-HSA-200425	"Carnitine metabolism"
LHES003774-PA	4	MetaCyc: PWY-5041;Reactome: R-HSA-156581;MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6	"S-adenosyl-L-methionine cycle II";"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism"
LHES016434-PA	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
LHES004368-PA	2	Reactome: R-HSA-5576886;Reactome: R-HSA-1299308	"Phase 4 - resting membrane potential";"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)"
LHES012289-PA	11	Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-3108214	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"SUMOylation of DNA damage response and repair proteins"
LHES015739-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
LHES014915-PA	11	Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-1971475;Reactome: R-HSA-2022928;Reactome: R-HSA-4420332;Reactome: R-HSA-975634;Reactome: R-HSA-202733;Reactome: R-HSA-3560783;Reactome: R-HSA-3560801;Reactome: R-HSA-3000170;Reactome: R-HSA-3656253	"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG biosynthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Retinoid metabolism and transport";"Cell surface interactions at the vascular wall";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GAT3 causes JDSSDHD";"Syndecan interactions";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS"
LHES006481-PA	42	MetaCyc: PWY-7007;KEGG: 00410+4.2.1.17;MetaCyc: PWY-1361;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;KEGG: 00360+4.2.1.17;MetaCyc: PWY-6944;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;MetaCyc: PWY-5138;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;MetaCyc: PWY-7094;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;MetaCyc: PWY-6863;MetaCyc: PWY-7726;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;MetaCyc: PWY-6583;KEGG: 00640+4.2.1.17;KEGG: 00592+4.2.1.17;KEGG: 00627+4.2.1.17;MetaCyc: PWY-5136;MetaCyc: PWY-7401;MetaCyc: PWY-6435;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7654;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;MetaCyc: PWY-6945;MetaCyc: PWY-5109	"Methyl ketone biosynthesis (engineered)";"beta-Alanine metabolism";"Benzoyl-coa degradation I (aerobic)";"Butanoate metabolism";"2-methylpropene degradation";"Caprolactam degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid elongation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Tryptophan metabolism";"Methyl tert-butyl ether degradation";"Phenylalanine metabolism";"Androstenedione degradation";"Lysine degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Butanoate metabolism";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Fatty acid salvage";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine degradation";"Limonene and pinene degradation";"Pyruvate fermentation to hexanol (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Benzoate degradation";"Pyruvate fermentation to butanol II (engineered)";"Geraniol degradation";"Spodoptera littoralis pheromone biosynthesis";"Pyruvate fermentation to butanol I";"Propanoate metabolism";"alpha-Linolenic acid metabolism";"Aminobenzoate degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"4-hydroxybenzoate biosynthesis III (plants)";"Toluene degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fatty acid degradation";"Fatty acid degradation";"Glutaryl-coa degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fermentation to 2-methylbutanoate"
LHES006457-PA	18	Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-6807505;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-77075;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-167160;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167287	"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"RNA polymerase II transcribes snRNA genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery"
LHES009098-PA	5	Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-204005	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"COPII-mediated vesicle transport"
LHES005880-PA	4	Reactome: R-HSA-4655427;Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300	"SUMOylation of DNA methylation proteins";"DNA methylation";"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA"
LHES002758-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
LHES001437-PA	11	Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-383280;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-212436	"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"Estrogen-dependent gene expression";"Nuclear Receptor transcription pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"Generic Transcription Pathway"
LHES009993-PA	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
LHES006931-PA	14	Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-426486;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-203927;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-426496;Reactome: R-HSA-9018519	"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Small interfering RNA (siRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"MicroRNA (miRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression"
LHES008567-PA	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
LHES009060-PA	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
LHES016561-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
LHES007353-PA	6	Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827	"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression"
LHES004318-PA	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
LHES000598-PA	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
LHES010041-PA	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
LHES017272-PA	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
LHES006703-PA	6	Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Ca2+ pathway"
LHES004634-PA	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
LHES003414-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
LHES007547-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
LHES005944-PA	6	Reactome: R-HSA-196780;MetaCyc: PWY-5789;MetaCyc: PWY-6722;MetaCyc: PWY-4381;MetaCyc: PWY-5744;MetaCyc: PWY-5743	"Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation";"3-hydroxypropanoate cycle"
LHES009644-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
LHES006146-PA	5	Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-196025	"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions"
LHES016870-PA	13	Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-156827	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression"
LHES009981-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
LHES013329-PA	22	Reactome: R-HSA-5628897;MetaCyc: PWY-7347;MetaCyc: PWY-622;KEGG: 00500+5.3.1.9;MetaCyc: PWY-5384;MetaCyc: PWY-6981;MetaCyc: PWY-6992;MetaCyc: PWY-5054;Reactome: R-HSA-70171;KEGG: 00030+5.3.1.9;MetaCyc: PWY-5659;MetaCyc: PWY-5514;Reactome: R-HSA-70263;Reactome: R-HSA-6798695;MetaCyc: PWY-7238;MetaCyc: PWY-621;KEGG: 00520+5.3.1.9;MetaCyc: PWY-6142;MetaCyc: PWY-3801;MetaCyc: PWY-8013;MetaCyc: PWY-7385;KEGG: 00010+5.3.1.9	"TP53 Regulates Metabolic Genes";"Sucrose biosynthesis III";"Starch biosynthesis";"Starch and sucrose metabolism";"Sucrose degradation IV (sucrose phosphorylase)";"Chitin biosynthesis";"1,5-anhydrofructose degradation";"D-sorbitol biosynthesis I";"Glycolysis";"Pentose phosphate pathway";"GDP-mannose biosynthesis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Gluconeogenesis";"Neutrophil degranulation";"Sucrose biosynthesis II";"Sucrose degradation III (sucrose invertase)";"Amino sugar and nucleotide sugar metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Sucrose degradation II (sucrose synthase)";"UDP-N-acetyl-D-galactosamine biosynthesis III";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis"
LHES004134-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
LHES009076-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
LHES016557-PA	5	Reactome: R-HSA-73817;KEGG: 00230+6.3.4.13;MetaCyc: PWY-6122;MetaCyc: PWY-6277;MetaCyc: PWY-6121	"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I"
LHES000346-PA	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
LHES009976-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
LHES007672-PA	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
LHES017180-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES015560-PA	1	Reactome: R-HSA-114608	"Platelet degranulation"
LHES004830-PA	5	MetaCyc: PWY-6891;MetaCyc: PWY-7560;KEGG: 00730+2.2.1.7;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6892	"Thiazole biosynthesis II (aerobic bacteria)";"Methylerythritol phosphate pathway II";"Thiamine metabolism";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis I (facultative anaerobic bacteria)"
LHES016822-PA	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
LHES010768-PA	17	KEGG: 00140+1.14.14.1;MetaCyc: PWY-5451;KEGG: 00232+1.14.14.1;KEGG: 00380+1.14.14.1;KEGG: 00591+1.14.14.1;MetaCyc: PWY-6398;KEGG: 00982+1.14.14.1;KEGG: 00830+1.14.14.1;MetaCyc: PWY-7466;KEGG: 00590+1.14.14.1;KEGG: 00627+1.14.14.1;Reactome: R-HSA-211981;MetaCyc: PWY-5665;KEGG: 00980+1.14.14.1;MetaCyc: PWY-7826;MetaCyc: PWY-6992;KEGG: 00071+1.14.14.1	"Steroid hormone biosynthesis";"Acetone degradation I (to methylglyoxal)";"Caffeine metabolism";"Tryptophan metabolism";"Linoleic acid metabolism";"Melatonin degradation I";"Drug metabolism - cytochrome P450";"Retinol metabolism";"Acetone degradation III (to propane-1,2-diol)";"Arachidonic acid metabolism";"Aminobenzoate degradation";"Xenobiotics";"Vanillin biosynthesis I";"Metabolism of xenobiotics by cytochrome P450";"Amaryllidacea alkaloids biosynthesis";"1,5-anhydrofructose degradation";"Fatty acid degradation"
LHES007441-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
LHES015812-PA	2	KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
LHES007411-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
LHES009063-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
LHES011253-PA	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
LHES003371-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
LHES001296-PA	1	Reactome: R-HSA-156590	"Glutathione conjugation"
LHES012940-PA	6	KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis"
LHES003702-PA	3	MetaCyc: PWY-7286;MetaCyc: PWY-7285;MetaCyc: PWY-6829	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis";"Trna methylation (yeast)"
LHES011720-PA	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
LHES012401-PA	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
LHES001658-PA	27	Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-180746	"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein"
LHES004969-PA	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
LHES007093-PA	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
LHES015055-PA	3	Reactome: R-HSA-204005;Reactome: R-HSA-162658;Reactome: R-HSA-6807878	"COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPI-mediated anterograde transport"
LHES015547-PA	1	Reactome: R-HSA-427589	"Type II Na+/Pi cotransporters"
LHES013801-PA	4	KEGG: 00983+6.3.5.2;Reactome: R-HSA-73817;MetaCyc: PWY-7221;KEGG: 00230+6.3.5.2	"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
LHES012180-PA	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
LHES005075-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
LHES006718-PA	4	MetaCyc: PWY-5030;Reactome: R-HSA-70921;KEGG: 00340+4.2.1.49;MetaCyc: PWY-5028	"L-histidine degradation III";"Histidine catabolism";"Histidine metabolism";"L-histidine degradation II"
LHES001715-PA	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
LHES011618-PA	3	Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis"
LHES000110-PA	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
LHES003348-PA	4	KEGG: 00534+2.4.2.26;MetaCyc: PWY-6557;Reactome: R-HSA-1971475;KEGG: 00532+2.4.2.26	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Glycosaminoglycan-protein linkage region biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate"
LHES007902-PA	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
LHES005360-PA	60	KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;KEGG: 00930+4.2.1.17;MetaCyc: PWY-5138;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;MetaCyc: PWY-7094;KEGG: 00903+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;MetaCyc: PWY-7606;KEGG: 00720+4.2.1.17;Reactome: R-HSA-77305;KEGG: 00650+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.211;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;MetaCyc: PWY-6944;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7007;KEGG: 00380+4.2.1.17;KEGG: 00410+4.2.1.17;KEGG: 00362+4.2.1.17;Reactome: R-HSA-77346;MetaCyc: PWY-1361;Reactome: R-HSA-1482798;KEGG: 00281+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;Reactome: R-HSA-77285;Reactome: R-HSA-77348;Reactome: R-HSA-77288;MetaCyc: PWY-6945;MetaCyc: PWY-5109;MetaCyc: PWY-6435;KEGG: 00623+1.1.1.35;KEGG: 00280+4.2.1.17;MetaCyc: PWY-6883;KEGG: 00062+4.2.1.17+1.1.1.211;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17;MetaCyc: PWY-7656;Reactome: R-HSA-77310;MetaCyc: PWY-6583;KEGG: 00640+4.2.1.17;KEGG: 00592+4.2.1.17;KEGG: 00627+4.2.1.17;MetaCyc: PWY-5136;MetaCyc: PWY-7401;MetaCyc: PWY-6863;MetaCyc: PWY-7726;KEGG: 00362+4.2.1.17+1.1.1.35;Reactome: R-HSA-77350	"Lysine degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Caprolactam degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Butanoate metabolism";"Carbon fixation pathways in prokaryotes";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Fatty acid salvage";"Limonene and pinene degradation";"Valine, leucine and isoleucine degradation";"Butanoate metabolism";"Caprolactam degradation";"2-methylpropene degradation";"Fatty acid elongation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Carbon fixation pathways in prokaryotes";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Butanoate metabolism";"Fatty acid degradation";"Tryptophan metabolism";"Methyl tert-butyl ether degradation";"Androstenedione degradation";"Phenylalanine metabolism";"Methyl ketone biosynthesis (engineered)";"Tryptophan metabolism";"beta-Alanine metabolism";"Benzoate degradation";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Benzoyl-coa degradation I (aerobic)";"Acyl chain remodeling of CL";"Geraniol degradation";"Fatty acid degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fatty acid degradation";"Glutaryl-coa degradation";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fermentation to 2-methylbutanoate";"4-hydroxybenzoate biosynthesis III (plants)";"Toluene degradation";"Valine, leucine and isoleucine degradation";"Pyruvate fermentation to butanol II (engineered)";"Fatty acid elongation";"Geraniol degradation";"Lysine degradation";"Spodoptera littoralis pheromone biosynthesis";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Pyruvate fermentation to butanol I";"Propanoate metabolism";"alpha-Linolenic acid metabolism";"Aminobenzoate degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Pyruvate fermentation to hexanol (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Benzoate degradation";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA"
LHES008296-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
LHES000986-PA	10	MetaCyc: PWY-6365;MetaCyc: PWY-4661;KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-6554;Reactome: R-HSA-983231;Reactome: R-HSA-1855204;Reactome: R-HSA-1855167;MetaCyc: PWY-6362;KEGG: 04070+2.7.1.159;MetaCyc: PWY-6366	"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Factors involved in megakaryocyte development and platelet production";"Synthesis of IP3 and IP4 in the cytosol";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis"
LHES003160-PA	2	Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
LHES007430-PA	13	KEGG: 00531+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52	"Glycosaminoglycan degradation";"CS/DS degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series"
LHES016292-PA	1	KEGG: 00970+6.1.1.5	"Aminoacyl-tRNA biosynthesis"
LHES008085-PA	3	Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-430039	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease"
LHES000087-PA	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
LHES015546-PA	16	Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-156902	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation"
LHES016610-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
LHES009202-PA	5	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-159231	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript"
LHES003285-PA	2	Reactome: R-HSA-1799339;Reactome: R-HSA-446203	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation"
LHES004654-PA	3	Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3	"Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism"
LHES014153-PA	3	KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857;Reactome: R-HSA-192456	"Glycerolipid metabolism";"Retinol biosynthesis";"Digestion of dietary lipid"
LHES014436-PA	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
LHES010928-PA	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
LHES012333-PA	12	KEGG: 00620+6.2.1.1;KEGG: 00630+6.2.1.1;MetaCyc: PWY-6672;MetaCyc: PWY-5108;KEGG: 00720+6.2.1.1;KEGG: 00010+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-5132;MetaCyc: PWY-5133;MetaCyc: PWY-7118;MetaCyc: PWY-7857;KEGG: 00680+6.2.1.1	"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"Cis-genanyl-coa degradation";"L-isoleucine biosynthesis V";"Carbon fixation pathways in prokaryotes";"Glycolysis / Gluconeogenesis";"Propanoate metabolism";"Lupulone and humulone biosynthesis";"Colupulone and cohumulone biosynthesis";"Chitin degradation to ethanol";"Adlupulone and adhumulone biosynthesis";"Methane metabolism"
LHES007176-PA	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
LHES003024-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
LHES002341-PA	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
LHES013339-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
LHES001952-PA	14	KEGG: 00650+1.3.5.1;KEGG: 00190+1.3.5.1;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-7279;Reactome: R-HSA-611105;MetaCyc: PWY-4302;KEGG: 00020+1.3.5.1;MetaCyc: PWY-561;MetaCyc: PWY-3781;MetaCyc: PWY-6969;MetaCyc: PWY-7254;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6728	"Butanoate metabolism";"Oxidative phosphorylation";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Aerobic respiration II (cytochrome c) (yeast)";"Respiratory electron transport";"Aerobic respiration III (alternative oxidase pathway)";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration I (cytochrome c)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle"
LHES005907-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
LHES007611-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
LHES000439-PA	1	Reactome: R-HSA-71064	"Lysine catabolism"
LHES015937-PA	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
LHES007528-PA	2	Reactome: R-HSA-977606;Reactome: R-HSA-174577	"Regulation of Complement cascade";"Activation of C3 and C5"
LHES003432-PA	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
LHES016880-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
LHES008677-PA	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
LHES007807-PA	5	MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317	"D-galactose detoxification";"Galactose metabolism";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)"
LHES003196-PA	19	Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-6790901;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-3214858;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-8876725;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-975956	"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"rRNA modification in the nucleus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"RMTs methylate histone arginines";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Protein methylation";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
LHES000830-PA	6	Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
LHES016097-PA	3	MetaCyc: PWY-7511;Reactome: R-HSA-1358803;Reactome: R-HSA-983168	"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation"
LHES014003-PA	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
LHES002662-PA	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
LHES003001-PA	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
LHES014156-PA	6	MetaCyc: PWY-7791;KEGG: 00240+2.1.3.2;MetaCyc: PWY-7790;MetaCyc: PWY-5686;KEGG: 00250+2.1.3.2;Reactome: R-HSA-500753	"UMP biosynthesis III";"Pyrimidine metabolism";"UMP biosynthesis II";"UMP biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Pyrimidine biosynthesis"
LHES004216-PA	3	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
LHES001274-PA	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
LHES002528-PA	1	Reactome: R-HSA-8981607	"Intracellular oxygen transport"
LHES007666-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
LHES006798-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES010626-PA	13	Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553	"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs"
LHES003653-PA	3	Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118	"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors"
LHES012572-PA	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
LHES001695-PA	1	Reactome: R-HSA-5689603	"UCH proteinases"
LHES002427-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
LHES001415-PA	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
LHES006036-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
LHES003350-PA	8	MetaCyc: PWY-7400;MetaCyc: PWY-4983;Reactome: R-HSA-70635;MetaCyc: PWY-5154;KEGG: 00220+4.3.2.1;MetaCyc: PWY-5;MetaCyc: PWY-4984;KEGG: 00250+4.3.2.1	"L-arginine biosynthesis IV (archaebacteria)";"Nitric oxide biosynthesis II (mammals)";"Urea cycle";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Arginine biosynthesis";"Canavanine biosynthesis";"Urea cycle";"Alanine, aspartate and glutamate metabolism"
LHES011083-PA	14	MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7724;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7619	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis"
LHES005082-PA	2	Reactome: R-HSA-418555;Reactome: R-HSA-444821	"G alpha (s) signalling events";"Relaxin receptors"
LHES015589-PA	18	MetaCyc: PWY-7417;Reactome: R-HSA-1482922;MetaCyc: PWY-8051;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-7783;Reactome: R-HSA-1482925;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7409;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-1483166;KEGG: 00591+3.1.1.4	"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Anandamide biosynthesis I";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Acyl chain remodelling of PS";"Plasmalogen degradation";"Acyl chain remodelling of PG";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Acyl chain remodelling of PC";"Synthesis of PA";"Linoleic acid metabolism"
LHES001696-PA	1	Reactome: R-HSA-5689603	"UCH proteinases"
LHES012735-PA	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
LHES012512-PA	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
LHES012485-PA	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
LHES004535-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
LHES008034-PA	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
LHES010163-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
LHES012775-PA	1	Reactome: R-HSA-6806664	"Metabolism of vitamin K"
LHES010482-PA	19	MetaCyc: PWY-7606;MetaCyc: PWY-7338;MetaCyc: PWY-7574;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-735;MetaCyc: PWY-7726;MetaCyc: PWY-7858;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7288;MetaCyc: PWY-7340;MetaCyc: PWY-7007;KEGG: 00640+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-6837;MetaCyc: PWY-6920;KEGG: 00592+1.3.3.6	"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoyl-coa degradation II";"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(5Z)-dodecenoate biosynthesis II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"6-gingerol analog biosynthesis (engineered)";"alpha-Linolenic acid metabolism"
LHES001208-PA	29	Reactome: R-HSA-5696400;Reactome: R-HSA-75955;Reactome: R-HSA-6781827;Reactome: R-HSA-167152;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-5696395;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-167158;Reactome: R-HSA-6781823;Reactome: R-HSA-73762;Reactome: R-HSA-113418;Reactome: R-HSA-76042	"Dual Incision in GG-NER";"RNA Polymerase II Transcription Elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV elongation complex in the absence of HIV Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"RNA Polymerase I Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"Formation of the HIV-1 Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Initiation";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
LHES002866-PA	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
LHES002347-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
LHES000636-PA	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
LHES015459-PA	13	Reactome: R-HSA-74259;KEGG: 00230+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-6545;MetaCyc: PWY-7187;MetaCyc: PWY-7206;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00760+3.6.1.9;KEGG: 00230+3.6.1.66;KEGG: 00770+3.6.1.9	"Purine catabolism";"Purine metabolism";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides dephosphorylation";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Tunicamycin biosynthesis";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Pantothenate and CoA biosynthesis"
LHES002673-PA	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
LHES007054-PA	2	Reactome: R-HSA-1369007;Reactome: R-HSA-5683371	"Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)"
LHES011640-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
LHES008944-PA	9	KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Other glycan degradation";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
LHES003543-PA	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
LHES003773-PA	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
LHES004799-PA	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
LHES001180-PA	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
LHES013674-PA	5	Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-75105	"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis"
LHES009688-PA	52	Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-349425;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-5607761;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-69601;Reactome: R-HSA-4608870;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-68827;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-5658442	"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Dectin-1 mediated noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Asymmetric localization of PCP proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Degradation of DVL";"ABC-family proteins mediated transport";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Regulation of RAS by GAPs"
LHES011637-PA	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
LHES004453-PA	4	MetaCyc: PWY-8072;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8040;MetaCyc: PWY-7383	"Alanine racemization";"D-Alanine metabolism";"Ansatrienin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)"
LHES000046-PA	1	Reactome: R-HSA-977443	"GABA receptor activation"
LHES009697-PA	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
LHES011265-PA	7	Reactome: R-HSA-198323;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-8854214;Reactome: R-HSA-5628897;Reactome: R-HSA-5674400;Reactome: R-HSA-165181	"AKT phosphorylates targets in the cytosol";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"TBC/RABGAPs";"TP53 Regulates Metabolic Genes";"Constitutive Signaling by AKT1 E17K in Cancer";"Inhibition of TSC complex formation by PKB"
LHES000927-PA	3	Reactome: R-HSA-5632968;Reactome: R-HSA-5632928;Reactome: R-HSA-5358565	"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
LHES005127-PA	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
LHES004006-PA	2	Reactome: R-HSA-196819;KEGG: 00230+4.6.1.1	"Vitamin B1 (thiamin) metabolism";"Purine metabolism"
LHES016266-PA	4	Reactome: R-HSA-1799339;Reactome: R-HSA-6798695;Reactome: R-HSA-446203;Reactome: R-HSA-879415	"SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation";"Asparagine N-linked glycosylation";"Advanced glycosylation endproduct receptor signaling"
LHES008497-PA	27	Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-180746	"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein"
LHES012850-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
LHES001458-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
LHES008202-PA	3	KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10;Reactome: R-HSA-379716	"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
LHES000822-PA	5	MetaCyc: PWY-7902;MetaCyc: PWY-5667;KEGG: 00564+1.1.1.94;MetaCyc: PWY-5981;Reactome: R-HSA-1483166	"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA"
LHES000482-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
LHES016247-PA	4	Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878	"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-mediated anterograde transport"
LHES008104-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
LHES006663-PA	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
LHES014795-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
LHES015250-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
LHES015726-PA	4	MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
LHES004195-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
LHES007658-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
LHES008449-PA	12	MetaCyc: PWY-5871;MetaCyc: PWY-5857;MetaCyc: PWY-7233;MetaCyc: PWY-5856;MetaCyc: PWY-5870;MetaCyc: PWY-5855;Reactome: R-HSA-2142789;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-6708;MetaCyc: PWY-5873;MetaCyc: PWY-5872;MetaCyc: PWY-7230	"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)"
LHES010900-PA	5	Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
LHES002325-PA	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
LHES007898-PA	3	Reactome: R-HSA-72165;Reactome: R-HSA-191859;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"snRNP Assembly";"mRNA Splicing - Major Pathway"
LHES002017-PA	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
LHES016900-PA	3	KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942;Reactome: R-HSA-174403	"Glutathione metabolism";"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling"
LHES001833-PA	3	Reactome: R-HSA-9609690;Reactome: R-HSA-3899300;Reactome: R-HSA-6804757	"HCMV Early Events";"SUMOylation of transcription cofactors";"Regulation of TP53 Degradation"
LHES009419-PA	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
LHES005013-PA	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
LHES001036-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
LHES002575-PA	1	Reactome: R-HSA-8951664	"Neddylation"
LHES003448-PA	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
LHES010446-PA	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
LHES015729-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
LHES001917-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
LHES004081-PA	5	Reactome: R-HSA-379726;Reactome: R-HSA-2408522;Reactome: R-HSA-6782315;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.15	"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism";"tRNA modification in the nucleus and cytosol";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
LHES007247-PA	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
LHES000089-PA	3	Reactome: R-HSA-6787639;KEGG: 00540+2.7.1.168;MetaCyc: PWY-6478	"GDP-fucose biosynthesis";"Lipopolysaccharide biosynthesis";"GDP-D-glycero-alpha-D-manno-heptose biosynthesis"
LHES002723-PA	5	Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes"
LHES005511-PA	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
LHES016841-PA	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
LHES010732-PA	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
LHES011543-PA	4	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379726	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
LHES011726-PA	11	MetaCyc: PWY-7124;MetaCyc: PWY-7268;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-7254;KEGG: 00720+1.1.1.42;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6549;KEGG: 00480+1.1.1.42;Reactome: R-HSA-71403;MetaCyc: PWY-5913	"Ethylene biosynthesis V (engineered)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"L-glutamine biosynthesis III";"Glutathione metabolism";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)"
LHES006848-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
LHES001795-PA	12	Reactome: R-HSA-2122947;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-5250924;Reactome: R-HSA-2894862;Reactome: R-HSA-1912408;Reactome: R-HSA-3214847;Reactome: R-HSA-350054;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-73762;Reactome: R-HSA-210744	"NOTCH1 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"B-WICH complex positively regulates rRNA expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"HATs acetylate histones";"Notch-HLH transcription pathway";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RNA Polymerase I Transcription Initiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"
LHES006496-PA	27	Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-165054	"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA"
LHES012714-PA	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
LHES002140-PA	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
LHES011397-PA	5	MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)"
LHES003270-PA	3	KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B;Reactome: R-HSA-6798695	"Folate biosynthesis";"Glutamate removal from folates";"Neutrophil degranulation"
LHES004402-PA	6	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
LHES000483-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
LHES000208-PA	13	Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553	"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs"
LHES006026-PA	6	Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695	"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex"
LHES001740-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
LHES015041-PA	17	MetaCyc: PWY-7205;MetaCyc: PWY-7187;MetaCyc: PWY-7184;MetaCyc: PWY-7176;MetaCyc: PWY-7224;KEGG: 00983+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7197;MetaCyc: PWY-7226;KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7222;MetaCyc: PWY-7221;MetaCyc: PWY-7210;MetaCyc: PWY-7227;MetaCyc: PWY-7198	"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
LHES013330-PA	1	Reactome: R-HSA-8951664	"Neddylation"
LHES013762-PA	7	Reactome: R-HSA-69205;Reactome: R-HSA-196757;Reactome: R-HSA-1474151;KEGG: 00670+1.5.1.3;KEGG: 00790+1.5.1.3;MetaCyc: PWY-6614;MetaCyc: PWY-3841	"G1/S-Specific Transcription";"Metabolism of folate and pterines";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"One carbon pool by folate";"Folate biosynthesis";"Tetrahydrofolate biosynthesis";"Folate transformations II (plants)"
LHES016585-PA	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
LHES015052-PA	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
LHES009049-PA	5	Reactome: R-HSA-70263;KEGG: 00020+4.1.1.32;MetaCyc: PWY-7383;KEGG: 00620+4.1.1.32;KEGG: 00010+4.1.1.32	"Gluconeogenesis";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis"
LHES003165-PA	6	MetaCyc: PWY-7791;KEGG: 00240+2.1.3.2;MetaCyc: PWY-7790;KEGG: 00250+2.1.3.2;MetaCyc: PWY-5686;Reactome: R-HSA-500753	"UMP biosynthesis III";"Pyrimidine metabolism";"UMP biosynthesis II";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis I";"Pyrimidine biosynthesis"
LHES002014-PA	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
LHES002489-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
LHES000534-PA	4	KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084	"Citrate cycle (TCA cycle)";"Lysine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA"
LHES000912-PA	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
LHES010309-PA	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
LHES001349-PA	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
LHES001395-PA	4	Reactome: R-HSA-6807505;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"RNA polymerase II transcribes snRNA genes";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
LHES007490-PA	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
LHES006757-PA	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
LHES010069-PA	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
LHES002514-PA	7	Reactome: R-HSA-165181;Reactome: R-HSA-5628897;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;Reactome: R-HSA-1632852;Reactome: R-HSA-8854214;Reactome: R-HSA-380972	"Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"Macroautophagy";"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK"
LHES003363-PA	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
LHES013619-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"