Accession_ID Pathway_Count Pathway_IDs Pathway_Names JAMg_model_2849.1 4 Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" JAMg_model_3430.3 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" JAMg_model_10547.2 6 Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion" JAMg_model_10600.4 14 Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-426486;Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519 "Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"Small interfering RNA (siRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression" JAMg_model_291.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_14209.1 3 KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807;Reactome: R-HSA-6798695 "Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation" JAMg_model_9920.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" JAMg_model_4083.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" JAMg_model_2850.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72702 "Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition" JAMg_model_10507.2 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" JAMg_model_2463.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" JAMg_model_12706.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" JAMg_model_7829.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" JAMg_model_4486.1 4 Reactome: R-HSA-72086;Reactome: R-HSA-167160;MetaCyc: PWY-7375;Reactome: R-HSA-77075 "mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE" JAMg_model_15493.4 20 MetaCyc: PWY-7007;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7726;MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7338;MetaCyc: PWY-7854;MetaCyc: PWY-735;MetaCyc: PWY-7291;MetaCyc: PWY-5136;Reactome: R-HSA-9033241;MetaCyc: PWY-6920;MetaCyc: PWY-7340;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7574;MetaCyc: PWY-7337 "Methyl ketone biosynthesis (engineered)";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Peroxisomal protein import";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoyl-coa degradation II";"10-cis-heptadecenoyl-CoA degradation (yeast)" JAMg_model_2389.2 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" JAMg_model_18048.3 5 Reactome: R-HSA-70171;MetaCyc: PWY-6906;MetaCyc: PWY-5514;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855 "Glycolysis";"Chitin derivatives degradation";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)" JAMg_model_10797.10 1 Reactome: R-HSA-5676934 "Protein repair" JAMg_model_10759.1 8 Reactome: R-HSA-606279;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-6783310;Reactome: R-HSA-2467813 "Deposition of new CENPA-containing nucleosomes at the centromere";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Fanconi Anemia Pathway";"Separation of Sister Chromatids" JAMg_model_18319.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Peptide chain elongation" JAMg_model_20130.1 5 Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-176187 "Unwinding of DNA";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress" JAMg_model_8875.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_11653.1 6 KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-5530;MetaCyc: PWY-2221;MetaCyc: PWY-7165;KEGG: 00030+3.1.1.17 "Caprolactam degradation";"Ascorbate and aldarate metabolism";"Sorbitol biosynthesis II";"Entner-Doudoroff pathway III (semi-phosphorylative)";"L-ascorbate biosynthesis VI (engineered pathway)";"Pentose phosphate pathway" JAMg_model_17634.1 5 Reactome: R-HSA-380994;Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781 "ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression" JAMg_model_19799.1 5 Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-983170 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" JAMg_model_10201.1 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_15747.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_10149.1 3 Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14 "Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis" JAMg_model_20950.1 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" JAMg_model_19133.4 13 MetaCyc: PWY-5537;Reactome: R-HSA-71403;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5913;MetaCyc: PWY-5392;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-5538;MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5 "Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism" JAMg_model_13527.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-6803205 "RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain" JAMg_model_16502.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" JAMg_model_14082.1 2 MetaCyc: PWY-7285;MetaCyc: PWY-7286 "Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis" JAMg_model_11878.2 6 MetaCyc: PWY-5067;MetaCyc: PWY-622;Reactome: R-HSA-189085;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1 "Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis";"Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch and sucrose metabolism" JAMg_model_20988.3 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" JAMg_model_164.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" JAMg_model_16685.2 1 Reactome: R-HSA-1632852 "Macroautophagy" JAMg_model_2271.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" JAMg_model_14134.2 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" JAMg_model_17091.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_8006.2 10 Reactome: R-HSA-4717374;MetaCyc: PWY-7979;MetaCyc: PWY-7921;Reactome: R-HSA-913709;Reactome: R-HSA-162699;MetaCyc: PWY-7661;Reactome: R-HSA-4719377;MetaCyc: PWY-7922;KEGG: 00510+2.4.1.83;Reactome: R-HSA-4719360 "Defective DPM1 causes DPM1-CDG (CDG-1e)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"O-linked glycosylation of mucins";"Synthesis of dolichyl-phosphate mannose";"Protein N-glycosylation (Haloferax volcanii)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"N-Glycan biosynthesis";"Defective DPM3 causes DPM3-CDG (CDG-1o)" JAMg_model_18080.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689 "Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits" JAMg_model_18296.2 7 Reactome: R-HSA-70221;MetaCyc: PWY-5941;MetaCyc: PWY-7238;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6724;Reactome: R-HSA-6798695;MetaCyc: PWY-6737 "Glycogen breakdown (glycogenolysis)";"Glycogen degradation II";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Starch degradation II";"Neutrophil degranulation";"Starch degradation V" JAMg_model_19495.1 4 MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7;Reactome: R-HSA-1362409;Reactome: R-HSA-947581 "[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism";"Mitochondrial iron-sulfur cluster biogenesis";"Molybdenum cofactor biosynthesis" JAMg_model_12733.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_12329.2 14 MetaCyc: PWY-6728;KEGG: 00720+1.3.5.1;MetaCyc: PWY-561;MetaCyc: PWY-5690;MetaCyc: PWY-4302;KEGG: 00020+1.3.5.1;MetaCyc: PWY-3781;Reactome: R-HSA-611105;Reactome: R-HSA-71403;MetaCyc: PWY-7279;KEGG: 00190+1.3.5.1;MetaCyc: PWY-7254;KEGG: 00650+1.3.5.1;MetaCyc: PWY-6969 "Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"Aerobic respiration III (alternative oxidase pathway)";"Citrate cycle (TCA cycle)";"Aerobic respiration I (cytochrome c)";"Respiratory electron transport";"Citric acid cycle (TCA cycle)";"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation";"TCA cycle VII (acetate-producers)";"Butanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" JAMg_model_11914.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" JAMg_model_583.8 1 Reactome: R-HSA-71384 "Ethanol oxidation" JAMg_model_6598.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_12755.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" JAMg_model_18163.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" JAMg_model_20068.1 5 Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" JAMg_model_13562.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72706 "Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit" JAMg_model_7510.2 3 MetaCyc: PWY-7426;Reactome: R-HSA-975574;KEGG: 00510+2.4.1.144 "Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the hybrid N-glycan synthesis pathway";"N-Glycan biosynthesis" JAMg_model_5213.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" JAMg_model_20864.2 12 KEGG: 00680+6.2.1.1;KEGG: 00720+6.2.1.1;KEGG: 00620+6.2.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-5108;KEGG: 00640+6.2.1.1;KEGG: 00630+6.2.1.1;KEGG: 00010+6.2.1.1;MetaCyc: PWY-5133;MetaCyc: PWY-7857;MetaCyc: PWY-5132;MetaCyc: PWY-6672 "Methane metabolism";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Chitin degradation to ethanol";"L-isoleucine biosynthesis V";"Propanoate metabolism";"Glyoxylate and dicarboxylate metabolism";"Glycolysis / Gluconeogenesis";"Colupulone and cohumulone biosynthesis";"Adlupulone and adhumulone biosynthesis";"Lupulone and humulone biosynthesis";"Cis-genanyl-coa degradation" JAMg_model_3812.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" JAMg_model_7327.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" JAMg_model_21085.1 6 Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-5693571 "RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Nonhomologous End-Joining (NHEJ)" JAMg_model_20576.2 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" JAMg_model_4530.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" JAMg_model_20123.1 8 Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-4551638;Reactome: R-HSA-3214841;Reactome: R-HSA-2559580;Reactome: R-HSA-8953750;Reactome: R-HSA-5617472;Reactome: R-HSA-8943724 "HCMV Early Events";"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins";"PKMTs methylate histone lysines";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by E2F6";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of PTEN gene transcription" JAMg_model_13613.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_6617.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" JAMg_model_13722.1 3 MetaCyc: PWY-5067;Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11 "Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis";"Starch and sucrose metabolism" JAMg_model_15508.5 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" JAMg_model_1711.1 3 Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5656121 "Translesion synthesis by POLK";"Translesion synthesis by REV1";"Translesion synthesis by POLI" JAMg_model_446.4 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_9569.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_18891.2 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" JAMg_model_16244.1 3 MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546 "Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)" JAMg_model_10689.5 6 Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-6791226 "mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_17530.2 4 Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)" JAMg_model_3670.3 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" JAMg_model_12366.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_340.2 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" JAMg_model_12824.2 6 Reactome: R-HSA-2022090;Reactome: R-HSA-8874081;Reactome: R-HSA-8948216;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490 "Assembly of collagen fibrils and other multimeric structures";"MET activates PTK2 signaling";"Collagen chain trimerization";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"Collagen degradation" JAMg_model_13298.2 2 KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019 "Pyrimidine metabolism";"Pseudouridine degradation" JAMg_model_13215.2 32 Reactome: R-HSA-110314;Reactome: R-HSA-6804756;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121;Reactome: R-HSA-6783310;Reactome: R-HSA-6782135;Reactome: R-HSA-3371511;Reactome: R-HSA-3214847;Reactome: R-HSA-5696395;Reactome: R-HSA-5656169;Reactome: R-HSA-5693607;Reactome: R-HSA-5689880;Reactome: R-HSA-6782210;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5358606;Reactome: R-HSA-201722;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-912446;Reactome: R-HSA-3108214;Reactome: R-HSA-5685938;Reactome: R-HSA-3371453;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-69166;Reactome: R-HSA-5693616;Reactome: R-HSA-68962;Reactome: R-HSA-174437;Reactome: R-HSA-5358565 "Recognition of DNA damage by PCNA-containing replication complex";"Regulation of TP53 Activity through Phosphorylation";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI";"Fanconi Anemia Pathway";"Dual incision in TC-NER";"HSF1 activation";"HATs acetylate histones";"Formation of Incision Complex in GG-NER";"Termination of translesion DNA synthesis";"Processing of DNA double-strand break ends";"Ub-specific processing proteases";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Formation of the beta-catenin:TCF transactivating complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Meiotic recombination";"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)";"Regulation of HSF1-mediated heat shock response";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)" JAMg_model_298.1 1 Reactome: R-HSA-419771 "Opsins" JAMg_model_8210.7 6 Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72695 "Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex" JAMg_model_8560.3 24 Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-1445148 "Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"HCMV Early Events";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" JAMg_model_6375.3 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_19081.6 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" JAMg_model_19548.1 1 Reactome: R-HSA-428359 "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA" JAMg_model_13641.1 2 Reactome: R-HSA-977225;Reactome: R-HSA-8854214 "Amyloid fiber formation";"TBC/RABGAPs" JAMg_model_19930.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_19491.5 4 Reactome: R-HSA-1362409;Reactome: R-HSA-947581;MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7 "Mitochondrial iron-sulfur cluster biogenesis";"Molybdenum cofactor biosynthesis";"[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism" JAMg_model_10213.3 8 Reactome: R-HSA-71336;KEGG: 00030+2.2.1.2;Reactome: R-HSA-8950505;MetaCyc: PWY-5723;Reactome: R-HSA-163754;Reactome: R-HSA-6791462;Reactome: R-HSA-6791055;MetaCyc: PWY-1861 "Pentose phosphate pathway";"Pentose phosphate pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Rubisco shunt";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" JAMg_model_4688.1 8 MetaCyc: PWY-7184;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7187;MetaCyc: PWY-7198;MetaCyc: PWY-6545;Reactome: R-HSA-499943;MetaCyc: PWY-7210 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" JAMg_model_12907.1 1 Reactome: R-HSA-9018519 "Estrogen-dependent gene expression" JAMg_model_20787.8 32 Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-9018519;Reactome: R-HSA-6803529;Reactome: R-HSA-76042;Reactome: R-HSA-72203;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-75953;Reactome: R-HSA-167242;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-8851708;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-167238;Reactome: R-HSA-72086;Reactome: R-HSA-168325;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-72163;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Estrogen-dependent gene expression";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"Signaling by FGFR2 IIIa TM";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Capping";"Viral Messenger RNA Synthesis";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Major Pathway";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex" JAMg_model_6854.1 13 MetaCyc: PWY-5497;MetaCyc: PWY-2201;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00720+6.3.4.3;MetaCyc: PWY-2161;MetaCyc: PWY-1722;MetaCyc: PWY-5030;Reactome: R-HSA-196757;KEGG: 00670+6.3.4.3;MetaCyc: PWY-3841;MetaCyc: PWY-6613;MetaCyc: PWY-7909 "Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Folate polyglutamylation";"Formate assimilation into 5,10-methylenetetrahydrofolate";"L-histidine degradation III";"Metabolism of folate and pterines";"One carbon pool by folate";"Folate transformations II (plants)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)" JAMg_model_17563.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" JAMg_model_12479.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_9788.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" JAMg_model_13764.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_12910.1 6 MetaCyc: PWY-2221;MetaCyc: PWY-7165;KEGG: 00030+3.1.1.17;KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-5530 "Entner-Doudoroff pathway III (semi-phosphorylative)";"L-ascorbate biosynthesis VI (engineered pathway)";"Pentose phosphate pathway";"Caprolactam degradation";"Ascorbate and aldarate metabolism";"Sorbitol biosynthesis II" JAMg_model_4492.1 9 Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-76042 "Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance" JAMg_model_11739.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_13441.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_19053.2 7 KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-5469 "Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Sesamin biosynthesis" JAMg_model_15441.4 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" JAMg_model_15097.2 8 Reactome: R-HSA-167590;Reactome: R-HSA-9636467;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-182218;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "Nef Mediated CD4 Down-regulation";"Blockage of phagosome acidification";"ROS and RNS production in phagocytes";"Ion channel transport";"Nef Mediated CD8 Down-regulation";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling" JAMg_model_1151.6 1 Reactome: R-HSA-8950505 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" JAMg_model_786.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" JAMg_model_17238.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_12508.2 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" JAMg_model_6423.3 7 KEGG: 00680+3.1.3.11;KEGG: 00010+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00051+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00710+3.1.3.11;KEGG: 00030+3.1.3.11 "Methane metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway" JAMg_model_7739.2 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" JAMg_model_11379.1 3 Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-429947 "KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Deadenylation of mRNA" JAMg_model_7420.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" JAMg_model_15228.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" JAMg_model_7576.2 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" JAMg_model_12498.2 3 Reactome: R-HSA-2022854;Reactome: R-HSA-5173105;Reactome: R-HSA-5083627 "Keratan sulfate biosynthesis";"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6" JAMg_model_15493.3 20 MetaCyc: PWY-7007;MetaCyc: PWY-7606;MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-735;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7288;MetaCyc: PWY-7574;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-6920;MetaCyc: PWY-7340;MetaCyc: PWY-5136;Reactome: R-HSA-9033241 "Methyl ketone biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II";"alpha-Linolenic acid metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoyl-coa degradation II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Peroxisomal protein import" JAMg_model_15268.5 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_796.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" JAMg_model_17962.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" JAMg_model_3401.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" JAMg_model_21022.3 13 Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Peptide chain elongation" JAMg_model_15277.8 10 KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-5497;MetaCyc: PWY-2201;MetaCyc: PWY-1722;Reactome: R-HSA-196757;MetaCyc: PWY-5030;MetaCyc: PWY-6613;MetaCyc: PWY-7909;MetaCyc: PWY-3841 "One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Metabolism of folate and pterines";"L-histidine degradation III";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)" JAMg_model_7407.1 1 Reactome: R-HSA-8963901 "Chylomicron remodeling" JAMg_model_3756.1 5 Reactome: R-HSA-1483148;KEGG: 00564+2.7.8.5;MetaCyc: PWY-5269;MetaCyc: PWY-5668;MetaCyc: PWY-7817 "Synthesis of PG";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis II";"Cardiolipin biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)" JAMg_model_16816.2 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" JAMg_model_14507.1 1 Reactome: R-HSA-2173788 "Downregulation of TGF-beta receptor signaling" JAMg_model_15712.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_10572.1 4 Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex" JAMg_model_5574.5 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" JAMg_model_20974.1 6 Reactome: R-HSA-913709;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290;Reactome: R-HSA-5083632 "O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)" JAMg_model_8298.6 4 Reactome: R-HSA-1912420;Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" JAMg_model_2702.1 2 KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788 "Starch and sucrose metabolism";"Cellulose degradation II (fungi)" JAMg_model_7883.3 1 Reactome: R-HSA-2565942 "Regulation of PLK1 Activity at G2/M Transition" JAMg_model_16083.3 3 Reactome: R-HSA-2514859;MetaCyc: PWY-7800;MetaCyc: PWY-7799 "Inactivation, recovery and regulation of the phototransduction cascade";"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)" JAMg_model_20674.1 56 Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5610783 "Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"FCERI mediated NF-kB activation";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome" JAMg_model_18689.1 6 MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085;MetaCyc: PWY-5067;MetaCyc: PWY-622 "Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis" JAMg_model_9899.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Viral mRNA Translation" JAMg_model_1774.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" JAMg_model_15627.1 4 Reactome: R-HSA-2408557;MetaCyc: PWY-6281;KEGG: 00970+2.9.1.2;KEGG: 00450+2.9.1.2 "Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism" JAMg_model_14959.2 6 Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Neutrophil degranulation";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport" JAMg_model_8587.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" JAMg_model_8481.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-8986944 "MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2" JAMg_model_1359.2 12 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-193648;Reactome: R-HSA-194840;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-418885;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416482 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"G alpha (q) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"DCC mediated attractive signaling";"Human immunodeficiency virus 1 infection";"G alpha (12/13) signalling events" JAMg_model_9564.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_10134.4 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" JAMg_model_5977.2 3 Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-948021 "COPII-mediated vesicle transport";"Cargo concentration in the ER";"Transport to the Golgi and subsequent modification" JAMg_model_9141.2 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" JAMg_model_16059.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-390471 "Major pathway of rRNA processing in the nucleolus and cytosol";"Association of TriC/CCT with target proteins during biosynthesis" JAMg_model_11230.1 5 Reactome: R-HSA-111464;Reactome: R-HSA-111457;Reactome: R-HSA-111469;Reactome: R-HSA-9627069;Reactome: R-HSA-111463 "SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Release of apoptotic factors from the mitochondria";"SMAC, XIAP-regulated apoptotic response";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs" JAMg_model_16528.3 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" JAMg_model_16053.1 5 MetaCyc: PWY-7790;MetaCyc: PWY-7791;Reactome: R-HSA-500753;MetaCyc: PWY-5686;KEGG: 00240+4.1.1.23 "UMP biosynthesis II";"UMP biosynthesis III";"Pyrimidine biosynthesis";"UMP biosynthesis I";"Pyrimidine metabolism" JAMg_model_10034.1 5 Reactome: R-HSA-9033500;Reactome: R-HSA-9033241;MetaCyc: PWY-7782;KEGG: 00565+2.5.1.26;Reactome: R-HSA-75896 "TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import";"Plasmalogen biosynthesis";"Ether lipid metabolism";"Plasmalogen biosynthesis" JAMg_model_6771.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" JAMg_model_2077.2 33 Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-168276 "SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways" JAMg_model_16346.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" JAMg_model_5075.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_8702.5 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" JAMg_model_16845.2 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" JAMg_model_14273.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" JAMg_model_8758.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_18325.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" JAMg_model_2714.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" JAMg_model_4976.2 7 MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-5466 "Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Matairesinol biosynthesis" JAMg_model_7587.4 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" JAMg_model_10741.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" JAMg_model_18171.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" JAMg_model_12710.4 6 MetaCyc: PWY-6898;Reactome: R-HSA-196819;MetaCyc: PWY-6907;MetaCyc: PWY-7356;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6908 "Thiamine salvage III";"Vitamin B1 (thiamin) metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage IV (yeast)";"Thiamine metabolism";"Thiamine diphosphate biosynthesis IV (eukaryotes)" JAMg_model_21110.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" JAMg_model_8112.1 2 KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10 "Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis" JAMg_model_11681.1 9 Reactome: R-HSA-156590;MetaCyc: PWY-6842;MetaCyc: PWY-7112;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-4061;KEGG: 00480+2.5.1.18;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18 "Glutathione conjugation";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - other enzymes";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450" JAMg_model_15049.1 5 Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-983170 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" JAMg_model_1413.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" JAMg_model_447.1 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_5303.1 4 MetaCyc: PWY-6129;KEGG: 00510+2.7.1.108;Reactome: R-HSA-446199;Reactome: R-HSA-4755583 "Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate";"Defective DOLK causes DOLK-CDG (CDG-1m)" JAMg_model_7357.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_11504.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_3162.2 6 Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation" JAMg_model_5587.9 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" JAMg_model_9724.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" JAMg_model_7968.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" JAMg_model_10797.5 1 Reactome: R-HSA-5676934 "Protein repair" JAMg_model_5850.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" JAMg_model_7092.4 5 KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6344;Reactome: R-HSA-8964539 "Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism" JAMg_model_6468.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" JAMg_model_13773.2 7 Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" JAMg_model_2928.6 7 KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" JAMg_model_2245.1 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" JAMg_model_10657.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" JAMg_model_9851.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_5950.1 2 Reactome: R-HSA-162791;Reactome: R-HSA-425561 "Attachment of GPI anchor to uPAR";"Sodium/Calcium exchangers" JAMg_model_12111.3 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" JAMg_model_8220.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_19133.2 13 MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5537;Reactome: R-HSA-71403;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-6969;MetaCyc: PWY-5913;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5 "Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Propanoate metabolism" JAMg_model_17038.2 2 Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" JAMg_model_1288.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" JAMg_model_8134.1 4 MetaCyc: PWY-5189;KEGG: 00860+4.2.1.75;Reactome: R-HSA-189451;MetaCyc: PWY-5188 "Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)" JAMg_model_8298.4 4 Reactome: R-HSA-1912420;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" JAMg_model_477.1 11 Reactome: R-HSA-418555;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-5610787 "G alpha (s) signalling events";"PKA activation in glucagon signalling";"Purine metabolism";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"PKA activation";"Hedgehog 'off' state" JAMg_model_10628.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" JAMg_model_574.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_19117.1 1 Reactome: R-HSA-200425 "Carnitine metabolism" JAMg_model_13521.4 8 Reactome: R-HSA-442720;Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-5610787 "CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"DARPP-32 events";"Hedgehog 'off' state" JAMg_model_21022.4 13 Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Peptide chain elongation" JAMg_model_480.4 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" JAMg_model_15311.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_559.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Viral mRNA Translation" JAMg_model_17282.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" JAMg_model_12837.1 1 Reactome: R-HSA-203754 "NOSIP mediated eNOS trafficking" JAMg_model_11907.2 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" JAMg_model_2446.2 5 Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-3214815 "RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones" JAMg_model_19163.1 3 Reactome: R-HSA-159740;MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90 "Gamma-carboxylation of protein precursors";"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis" JAMg_model_8370.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" JAMg_model_12679.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135 "mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER" JAMg_model_21196.2 1 Reactome: R-HSA-68962 "Activation of the pre-replicative complex" JAMg_model_6938.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_1293.1 6 KEGG: 00010+5.4.2.11;KEGG: 00260+5.4.2.11;KEGG: 00680+5.4.2.11;MetaCyc: PWY-5484;MetaCyc: PWY-1622;MetaCyc: PWY-8004 "Glycolysis / Gluconeogenesis";"Glycine, serine and threonine metabolism";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I" JAMg_model_15067.1 2 KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788 "Starch and sucrose metabolism";"Cellulose degradation II (fungi)" JAMg_model_1686.1 7 Reactome: R-HSA-6798695;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-390450 "Neutrophil degranulation";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC" JAMg_model_2272.2 3 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes" JAMg_model_11280.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" JAMg_model_19315.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_2365.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_6459.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" JAMg_model_2280.6 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" JAMg_model_5503.1 2 Reactome: R-HSA-9020702;Reactome: R-HSA-6798695 "Interleukin-1 signaling";"Neutrophil degranulation" JAMg_model_1970.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_3486.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" JAMg_model_21160.1 4 MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7204;Reactome: R-HSA-964975 "4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate" JAMg_model_20334.4 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" JAMg_model_10288.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" JAMg_model_19620.1 7 MetaCyc: PWY-7294;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7295;MetaCyc: PWY-7118;MetaCyc: PWY-7854;KEGG: 00630+2.3.3.9;MetaCyc: PWY-6969 "D-xylose degradation IV";"Pyruvate metabolism";"L-arabinose degradation IV";"Chitin degradation to ethanol";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Glyoxylate and dicarboxylate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" JAMg_model_3662.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827 "Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression" JAMg_model_17337.3 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" JAMg_model_10628.2 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" JAMg_model_2674.1 3 Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism" JAMg_model_8676.2 2 Reactome: R-HSA-70895;KEGG: 00280+1.3.8.4 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" JAMg_model_12281.6 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" JAMg_model_3930.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" JAMg_model_3670.2 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" JAMg_model_8393.2 2 Reactome: R-HSA-2408508;Reactome: R-HSA-389661 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation" JAMg_model_7256.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" JAMg_model_18325.5 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" JAMg_model_8807.2 7 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection" JAMg_model_16984.1 14 Reactome: R-HSA-5696397;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-110314;Reactome: R-HSA-5656169 "Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching";"Dual incision in TC-NER";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis" JAMg_model_5554.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" JAMg_model_12759.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" JAMg_model_8077.3 5 Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554 "Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" JAMg_model_6562.2 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_20791.1 14 Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167290 "Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation" JAMg_model_19885.3 2 Reactome: R-HSA-1799339;Reactome: R-HSA-1236974 "SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway" JAMg_model_5690.3 2 Reactome: R-HSA-606279;Reactome: R-HSA-6783310 "Deposition of new CENPA-containing nucleosomes at the centromere";"Fanconi Anemia Pathway" JAMg_model_12129.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" JAMg_model_6219.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" JAMg_model_21038.1 4 MetaCyc: PWY-7285;MetaCyc: PWY-7286;MetaCyc: PWY-6829;Reactome: R-HSA-6782861 "Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"Synthesis of wybutosine at G37 of tRNA(Phe)" JAMg_model_18440.7 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" JAMg_model_15530.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" JAMg_model_8885.5 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" JAMg_model_18181.2 13 Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs" JAMg_model_1491.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" JAMg_model_16589.8 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" JAMg_model_2309.1 3 Reactome: R-HSA-3108214;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395 "SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER" JAMg_model_5845.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" JAMg_model_2273.2 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" JAMg_model_8051.1 1 Reactome: R-HSA-71064 "Lysine catabolism" JAMg_model_19133.6 13 MetaCyc: PWY-6728;MetaCyc: PWY-7384;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5538;KEGG: 00720+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5537;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-6969;MetaCyc: PWY-5913 "Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)" JAMg_model_340.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" JAMg_model_21023.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_19491.6 4 MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7;Reactome: R-HSA-1362409;Reactome: R-HSA-947581 "[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism";"Mitochondrial iron-sulfur cluster biogenesis";"Molybdenum cofactor biosynthesis" JAMg_model_907.2 8 Reactome: R-HSA-190873;Reactome: R-HSA-432720;Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-196025 "Gap junction degradation";"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Formation of annular gap junctions" JAMg_model_2848.2 12 KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5913;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-6728;MetaCyc: PWY-7384 "Propanoate metabolism";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate VI";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)" JAMg_model_155.2 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" JAMg_model_1679.2 22 Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-5358752;Reactome: R-HSA-5467337;Reactome: R-HSA-5358749;Reactome: R-HSA-5675221;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-2467813;Reactome: R-HSA-5358747;Reactome: R-HSA-432142;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-6811558;Reactome: R-HSA-195253;Reactome: R-HSA-196299;Reactome: R-HSA-5673000;Reactome: R-HSA-5467340;Reactome: R-HSA-389513 "Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"S37 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Separation of Sister Chromatids";"S33 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Degradation of beta-catenin by the destruction complex";"Beta-catenin phosphorylation cascade";"RAF activation";"AXIN missense mutants destabilize the destruction complex";"CTLA4 inhibitory signaling" JAMg_model_17752.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" JAMg_model_1469.1 7 KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-6824 "Phenylpropanoid biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis" JAMg_model_16635.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" JAMg_model_16058.1 11 Reactome: R-HSA-193692;Reactome: R-HSA-1251985;Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-3928665;Reactome: R-HSA-2979096 "Regulated proteolysis of p75NTR";"Nuclear signaling by ERBB4";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH2 Activation and Transmission of Signal to the Nucleus" JAMg_model_3158.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" JAMg_model_17397.1 5 KEGG: 00281+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00072+4.1.3.4;KEGG: 00280+4.1.3.4;KEGG: 00650+4.1.3.4 "Geraniol degradation";"Mevalonate degradation";"Synthesis and degradation of ketone bodies";"Valine, leucine and isoleucine degradation";"Butanoate metabolism" JAMg_model_7415.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" JAMg_model_6740.1 5 MetaCyc: PWY-7180;Reactome: R-HSA-6798695;KEGG: 00030+4.1.2.4;Reactome: R-HSA-71336;MetaCyc: PWY-8060 "2-deoxy-alpha-D-ribose 1-phosphate degradation";"Neutrophil degranulation";"Pentose phosphate pathway";"Pentose phosphate pathway";"2-deoxy-D-ribose degradation I" JAMg_model_19704.1 2 Reactome: R-HSA-2022928;MetaCyc: PWY-6558 "HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)" JAMg_model_17345.1 27 Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142 "SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins" JAMg_model_15484.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_14549.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_15480.2 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" JAMg_model_21183.1 6 MetaCyc: PWY-7346;KEGG: 00053+1.1.1.22;Reactome: R-HSA-173599;MetaCyc: PWY-7820;KEGG: 00040+1.1.1.22;KEGG: 00520+1.1.1.22 "UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Ascorbate and aldarate metabolism";"Formation of the active cofactor, UDP-glucuronate";"Teichuronic acid biosynthesis (B. subtilis 168)";"Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism" JAMg_model_5088.6 16 MetaCyc: PWY-6142;KEGG: 00010+4.2.1.11;MetaCyc: PWY-7124;MetaCyc: PWY-7218;MetaCyc: PWY-1042;MetaCyc: PWY-6901;MetaCyc: PWY-2221;MetaCyc: PWY-7003;Reactome: R-HSA-70171;KEGG: 00680+4.2.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-5723;Reactome: R-HSA-70263;MetaCyc: PWY-8004;MetaCyc: PWY-6886;MetaCyc: PWY-1622 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Ethylene biosynthesis V (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycerol degradation to butanol";"Glycolysis";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Rubisco shunt";"Gluconeogenesis";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Formaldehyde assimilation I (serine pathway)" JAMg_model_11978.2 2 MetaCyc: PWY-7511;Reactome: R-HSA-5689880 "Protein ubiquitination";"Ub-specific processing proteases" JAMg_model_12757.2 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" JAMg_model_5375.1 26 Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-389960;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399 "Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"HCMV Early Events";"Mitotic Prometaphase";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Formation of tubulin folding intermediates by CCT/TriC";"Kinesins";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Aggrephagy" JAMg_model_1945.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" JAMg_model_2381.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012 "L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency" JAMg_model_3304.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-6790901 "Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol" JAMg_model_6845.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_20628.1 1 Reactome: R-HSA-912446 "Meiotic recombination" JAMg_model_11532.3 20 Reactome: R-HSA-1257604;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-166208;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5628897;KEGG: 05163+2.7.11.1;Reactome: R-HSA-389357;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-380972 "PIP3 activates AKT signaling";"Amino acids regulate mTORC1";"Macroautophagy";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"mTORC1-mediated signalling";"Relaxin signaling pathway";"TP53 Regulates Metabolic Genes";"Human cytomegalovirus infection";"CD28 dependent PI3K/Akt signaling";"Human immunodeficiency virus 1 infection";"VEGFR2 mediated vascular permeability";"HSF1-dependent transactivation";"mTOR signalling";"Regulation of PTEN gene transcription";"Thermogenesis";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"Energy dependent regulation of mTOR by LKB1-AMPK" JAMg_model_3756.3 5 Reactome: R-HSA-1483148;KEGG: 00564+2.7.8.5;MetaCyc: PWY-5269;MetaCyc: PWY-5668;MetaCyc: PWY-7817 "Synthesis of PG";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis II";"Cardiolipin biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)" JAMg_model_504.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_10328.7 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" JAMg_model_16393.2 4 KEGG: 00640+4.1.1.9;KEGG: 00410+4.1.1.9;Reactome: R-HSA-9033241;Reactome: R-HSA-390247 "Propanoate metabolism";"beta-Alanine metabolism";"Peroxisomal protein import";"Beta-oxidation of very long chain fatty acids" JAMg_model_10267.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" JAMg_model_9208.2 16 Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-983168 "CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_13545.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" JAMg_model_7481.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" JAMg_model_907.7 8 Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-190873;Reactome: R-HSA-432720 "Clathrin-mediated endocytosis";"Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Gap junction degradation";"Lysosome Vesicle Biogenesis" JAMg_model_13912.1 7 KEGG: 00220+3.5.3.1;MetaCyc: PWY-6922;MetaCyc: PWY-46;MetaCyc: PWY-31;MetaCyc: PWY-4984;KEGG: 00330+3.5.3.1;Reactome: R-HSA-70635 "Arginine biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Putrescine biosynthesis III";"Canavanine degradation";"Urea cycle";"Arginine and proline metabolism";"Urea cycle" JAMg_model_18117.4 12 MetaCyc: PWY-6936;MetaCyc: PWY-1187;KEGG: 00380+2.6.1.7;MetaCyc: PWY-601;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6309;Reactome: R-HSA-71240;MetaCyc: PWY-801;MetaCyc: PWY-7901;MetaCyc: PWY-2821;MetaCyc: PWY-6842;KEGG: 00270+4.4.1.13 "Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from homomethionine";"Tryptophan metabolism";"Glucosinolate biosynthesis from tryptophan";"Selenocompound metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan catabolism";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from phenylalanine";"Glutathione-mediated detoxification II";"Cysteine and methionine metabolism" JAMg_model_10183.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" JAMg_model_16732.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" JAMg_model_12928.4 14 MetaCyc: PWY-3781;KEGG: 00020+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-4302;MetaCyc: PWY-561;MetaCyc: PWY-6728;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6969;KEGG: 00650+1.3.5.1;MetaCyc: PWY-7254;MetaCyc: PWY-7279;KEGG: 00190+1.3.5.1;Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Aerobic respiration I (cytochrome c)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Aerobic respiration III (alternative oxidase pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Butanoate metabolism";"TCA cycle VII (acetate-producers)";"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation";"Respiratory electron transport";"Citric acid cycle (TCA cycle)" JAMg_model_20524.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" JAMg_model_10600.1 14 Reactome: R-HSA-8948700;Reactome: R-HSA-203927;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-426496 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs" JAMg_model_4858.1 2 Reactome: R-HSA-5362517;Reactome: R-HSA-204174 "Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex" JAMg_model_1556.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_8910.4 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" JAMg_model_2428.2 24 Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-1445148 "Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" JAMg_model_5066.1 18 MetaCyc: PWY-7115;MetaCyc: PWY-6638;KEGG: 00220+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00710+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00950+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-7383;MetaCyc: PWY-6643 "C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Sulfolactate degradation III";"Arginine biosynthesis";"Phenylalanine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Carbon fixation in photosynthetic organisms";"Arginine and proline metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"(R)-cysteate degradation";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"Alanine, aspartate and glutamate metabolism";"Novobiocin biosynthesis";"Cysteine and methionine metabolism";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Coenzyme M biosynthesis II" JAMg_model_21196.1 1 Reactome: R-HSA-68962 "Activation of the pre-replicative complex" JAMg_model_10858.1 7 KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00480+2.5.1.22 "Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Glutathione metabolism" JAMg_model_1988.3 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" JAMg_model_19538.1 14 MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7036 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II" JAMg_model_21230.1 2 Reactome: R-HSA-8934593;Reactome: R-HSA-69231 "Regulation of RUNX1 Expression and Activity";"Cyclin D associated events in G1" JAMg_model_6045.2 4 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" JAMg_model_359.3 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" JAMg_model_11741.2 24 Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-68877;Reactome: R-HSA-9609690 "RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"Aggrephagy";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"Mitotic Prometaphase";"HCMV Early Events" JAMg_model_16579.5 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_479.3 11 Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-432040 "Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"PKA activation";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins" JAMg_model_4562.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" JAMg_model_2764.4 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" JAMg_model_299.3 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" JAMg_model_5154.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" JAMg_model_14590.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" JAMg_model_9736.3 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" JAMg_model_13456.1 2 Reactome: R-HSA-5673001;Reactome: R-HSA-442982 "RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor" JAMg_model_19071.2 29 Reactome: R-HSA-6804756;Reactome: R-HSA-110314;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-6783310;Reactome: R-HSA-6782135;Reactome: R-HSA-912446;Reactome: R-HSA-3371511;Reactome: R-HSA-3108214;Reactome: R-HSA-5685938;Reactome: R-HSA-5696395;Reactome: R-HSA-3371453;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-176187;Reactome: R-HSA-69166;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-68962;Reactome: R-HSA-174437;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-5696397 "Regulation of TP53 Activity through Phosphorylation";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Fanconi Anemia Pathway";"Dual incision in TC-NER";"Meiotic recombination";"HSF1 activation";"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)";"Formation of Incision Complex in GG-NER";"Regulation of HSF1-mediated heat shock response";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of ATR in response to replication stress";"Removal of the Flap Intermediate";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in GG-NER" JAMg_model_4976.3 7 MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7 "Sesamin biosynthesis";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis" JAMg_model_5874.4 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_7995.4 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" JAMg_model_2543.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" JAMg_model_20427.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" JAMg_model_19622.1 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" JAMg_model_5119.1 11 Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-69017;Reactome: R-HSA-68689 "Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDK-mediated phosphorylation and removal of Cdc6";"CDC6 association with the ORC:origin complex" JAMg_model_12752.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" JAMg_model_9184.3 6 KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107 "Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" JAMg_model_9110.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" JAMg_model_7177.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_7696.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" JAMg_model_7500.4 19 MetaCyc: PWY-7606;MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7007;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7574;MetaCyc: PWY-5136;MetaCyc: PWY-6920;MetaCyc: PWY-7340;MetaCyc: PWY-7854;MetaCyc: PWY-735;MetaCyc: PWY-7291;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7288 "Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"Methyl ketone biosynthesis (engineered)";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation II (plant peroxisome)";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II";"alpha-Linolenic acid metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)" JAMg_model_4046.3 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" JAMg_model_4426.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-8949215 "Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport" JAMg_model_3319.3 22 Reactome: R-HSA-159236;KEGG: 00250+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00401+2.6.1.1;Reactome: R-HSA-72187;MetaCyc: PWY-6643;Reactome: R-HSA-73856;MetaCyc: PWY-7383;KEGG: 00220+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-7115;MetaCyc: PWY-7117;KEGG: 00960+2.6.1.1;Reactome: R-HSA-72163;MetaCyc: PWY-6642;KEGG: 00710+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00350+2.6.1.1 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"Alanine, aspartate and glutamate metabolism";"Cysteine and methionine metabolism";"Partial TCA cycle (obligate autotrophs)";"Novobiocin biosynthesis";"mRNA 3'-end processing";"Coenzyme M biosynthesis II";"RNA Polymerase II Transcription Termination";"Anaerobic energy metabolism (invertebrates, cytosol)";"Arginine biosynthesis";"Phenylalanine metabolism";"Sulfolactate degradation III";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"mRNA Splicing - Major Pathway";"(R)-cysteate degradation";"Carbon fixation in photosynthetic organisms";"Arginine and proline metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism" JAMg_model_12313.3 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" JAMg_model_4185.1 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" JAMg_model_12631.1 4 Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814 "Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes" JAMg_model_9331.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" JAMg_model_13098.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_10818.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_14765.4 3 Reactome: R-HSA-2980766;Reactome: R-HSA-2995383;Reactome: R-HSA-4419969 "Nuclear Envelope Breakdown";"Initiation of Nuclear Envelope Reformation";"Depolymerisation of the Nuclear Lamina" JAMg_model_10638.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827 "Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression" JAMg_model_19438.1 2 Reactome: R-HSA-425397;Reactome: R-HSA-5619061 "Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)" JAMg_model_7807.1 3 Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880 "TCF dependent signaling in response to WNT";"Degradation of AXIN";"Ub-specific processing proteases" JAMg_model_397.2 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" JAMg_model_5876.4 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_18709.1 19 Reactome: R-HSA-194840;Reactome: R-HSA-114604;Reactome: R-HSA-5626467;Reactome: R-HSA-5663213;Reactome: R-HSA-5663220;Reactome: R-HSA-418885;Reactome: R-HSA-5625970;Reactome: R-HSA-8964616;Reactome: R-HSA-182971;Reactome: R-HSA-389359;Reactome: R-HSA-983231;Reactome: R-HSA-8950505;Reactome: R-HSA-525793;Reactome: R-HSA-3928662;Reactome: R-HSA-4420097;Reactome: R-HSA-428543;Reactome: R-HSA-2029482;Reactome: R-HSA-5627123;Reactome: R-HSA-5687128 "Rho GTPase cycle";"GPVI-mediated activation cascade";"RHO GTPases activate IQGAPs";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases Activate Formins";"DCC mediated attractive signaling";"RHO GTPases activate KTN1";"G beta:gamma signalling through CDC42";"EGFR downregulation";"CD28 dependent Vav1 pathway";"Factors involved in megakaryocyte development and platelet production";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Myogenesis";"EPHB-mediated forward signaling";"VEGFA-VEGFR2 Pathway";"Inactivation of CDC42 and RAC1";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases activate PAKs";"MAPK6/MAPK4 signaling" JAMg_model_20663.1 5 Reactome: R-HSA-211976;Reactome: R-HSA-211945;Reactome: R-HSA-1989781;Reactome: R-HSA-8937144;Reactome: R-HSA-211981 "Endogenous sterols";"Phase I - Functionalization of compounds";"PPARA activates gene expression";"Aryl hydrocarbon receptor signalling";"Xenobiotics" JAMg_model_9096.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" JAMg_model_17775.6 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" JAMg_model_583.2 1 Reactome: R-HSA-71384 "Ethanol oxidation" JAMg_model_21315.3 15 MetaCyc: PWY-7003;Reactome: R-HSA-70171;MetaCyc: PWY-6142;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-7383;KEGG: 00230+2.7.1.40;MetaCyc: PWY-5723;MetaCyc: PWY-2221;MetaCyc: PWY-6886;MetaCyc: PWY-8004 "Glycerol degradation to butanol";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pyruvate metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Purine metabolism";"Rubisco shunt";"Entner-Doudoroff pathway III (semi-phosphorylative)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I" JAMg_model_12435.2 1 Reactome: R-HSA-1632852 "Macroautophagy" JAMg_model_20787.10 32 Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-168325;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-72203;Reactome: R-HSA-76042;Reactome: R-HSA-6803529;Reactome: R-HSA-9018519;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-73776 "mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Viral Messenger RNA Synthesis";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"FGFR2 alternative splicing";"Estrogen-dependent gene expression";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Promoter Escape" JAMg_model_3237.3 13 Reactome: R-HSA-8866427;Reactome: R-HSA-416993;Reactome: R-HSA-2132295;Reactome: R-HSA-167590;Reactome: R-HSA-5099900;Reactome: R-HSA-177504;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665;Reactome: R-HSA-8964038;Reactome: R-HSA-182218;Reactome: R-HSA-8856825;Reactome: R-HSA-437239;Reactome: R-HSA-8856828 "VLDLR internalisation and degradation";"Trafficking of GluR2-containing AMPA receptors";"MHC class II antigen presentation";"Nef Mediated CD4 Down-regulation";"WNT5A-dependent internalization of FZD4";"Retrograde neurotrophin signalling";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells";"LDL clearance";"Nef Mediated CD8 Down-regulation";"Cargo recognition for clathrin-mediated endocytosis";"Recycling pathway of L1";"Clathrin-mediated endocytosis" JAMg_model_9777.1 5 Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-5250924 "RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression" JAMg_model_20961.2 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" JAMg_model_15621.2 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" JAMg_model_19030.2 5 KEGG: 00250+1.2.1.88;Reactome: R-HSA-389661;Reactome: R-HSA-70688;MetaCyc: PWY-6853;KEGG: 00330+1.2.1.88 "Alanine, aspartate and glutamate metabolism";"Glyoxylate metabolism and glycine degradation";"Proline catabolism";"Ethylene biosynthesis II (microbes)";"Arginine and proline metabolism" JAMg_model_8153.5 3 Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3 "Serine biosynthesis";"Methane metabolism";"Glycine, serine and threonine metabolism" JAMg_model_12634.1 6 Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-69052 "Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state" JAMg_model_19062.2 8 KEGG: 00330+1.5.5.2;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;MetaCyc: PWY-5737;MetaCyc: PWY-6922;Reactome: R-HSA-70688 "Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Proline catabolism" JAMg_model_7404.2 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" JAMg_model_3663.4 5 KEGG: 00983+2.7.1.21;Reactome: R-HSA-73614;MetaCyc: PWY-7199;KEGG: 00240+2.7.1.21;Reactome: R-HSA-69205 "Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine metabolism";"G1/S-Specific Transcription" JAMg_model_15213.1 2 KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" JAMg_model_18911.1 2 Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77 "Methionine salvage pathway";"Cysteine and methionine metabolism" JAMg_model_4701.3 4 MetaCyc: PWY-5874;KEGG: 00860+1.14.14.18;Reactome: R-HSA-189483;Reactome: R-HSA-917937 "Heme degradation I";"Porphyrin and chlorophyll metabolism";"Heme degradation";"Iron uptake and transport" JAMg_model_1771.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" JAMg_model_13823.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" JAMg_model_16473.1 14 Reactome: R-HSA-196757;MetaCyc: PWY-3841;KEGG: 00460+2.1.2.1;KEGG: 00630+2.1.2.1;KEGG: 00680+2.1.2.1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-1622;MetaCyc: PWY-5497;MetaCyc: PWY-2201;KEGG: 00260+2.1.2.1;MetaCyc: PWY-2161;MetaCyc: PWY-3661;MetaCyc: PWY-181;MetaCyc: PWY-3661-1 "Metabolism of folate and pterines";"Folate transformations II (plants)";"Cyanoamino acid metabolism";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism";"One carbon pool by folate";"Formaldehyde assimilation I (serine pathway)";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"Glycine, serine and threonine metabolism";"Folate polyglutamylation";"Glycine betaine degradation I";"Photorespiration ";"Glycine betaine degradation II (mammalian)" JAMg_model_12230.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" JAMg_model_12965.2 4 Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" JAMg_model_12626.1 4 MetaCyc: PWY-2781;Reactome: R-HSA-6787450;KEGG: 00908+2.5.1.75;Reactome: R-HSA-6782315 "Cis-zeatin biosynthesis";"tRNA modification in the mitochondrion";"Zeatin biosynthesis";"tRNA modification in the nucleus and cytosol" JAMg_model_12807.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" JAMg_model_3411.3 1 Reactome: R-HSA-977347 "Serine biosynthesis" JAMg_model_10767.2 13 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956 "Viral mRNA Translation";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" JAMg_model_19716.2 5 KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979 "Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)" JAMg_model_8336.1 3 Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-8939243 "Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" JAMg_model_15111.1 4 KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" JAMg_model_2928.1 7 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection" JAMg_model_8803.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" JAMg_model_21103.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" JAMg_model_11895.3 5 MetaCyc: PWY-7159;MetaCyc: PWY-5531;KEGG: 00860+4.1.1.37;Reactome: R-HSA-189451;MetaCyc: PWY-7766 "3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Heme b biosynthesis IV (Gram-positive bacteria)" JAMg_model_13358.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" JAMg_model_21161.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942 "Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition" JAMg_model_10740.2 1 Reactome: R-HSA-6798163 "Choline catabolism" JAMg_model_838.1 1 Reactome: R-HSA-5683826 "Surfactant metabolism" JAMg_model_15706.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis" JAMg_model_19624.1 56 Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-4641257;Reactome: R-HSA-174084 "ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Interleukin-1 signaling";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FCERI mediated NF-kB activation";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C" JAMg_model_9202.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_16396.1 56 Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-180534 "Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4" JAMg_model_4485.7 4 MetaCyc: PWY-7437;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603 "Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"Other types of O-glycan biosynthesis";"UCH proteinases" JAMg_model_20943.2 2 Reactome: R-HSA-156588;Reactome: R-HSA-6798163 "Glucuronidation";"Choline catabolism" JAMg_model_6292.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" JAMg_model_12329.3 14 KEGG: 00190+1.3.5.1;MetaCyc: PWY-7279;Reactome: R-HSA-611105;Reactome: R-HSA-71403;MetaCyc: PWY-6969;KEGG: 00650+1.3.5.1;MetaCyc: PWY-7254;MetaCyc: PWY-561;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6728;MetaCyc: PWY-3781;KEGG: 00020+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-5690 "Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Respiratory electron transport";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Butanoate metabolism";"TCA cycle VII (acetate-producers)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Aerobic respiration I (cytochrome c)";"Citrate cycle (TCA cycle)";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle II (plants and fungi)" JAMg_model_9473.4 8 MetaCyc: PWY-7117;MetaCyc: PWY-5743;KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-7115;MetaCyc: PWY-5789;MetaCyc: PWY-241;MetaCyc: PWY-5744 "C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation" JAMg_model_20188.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" JAMg_model_15102.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" JAMg_model_9932.2 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_9953.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" JAMg_model_17550.2 8 Reactome: R-HSA-6781823;Reactome: R-HSA-8948747;Reactome: R-HSA-6782210;Reactome: R-HSA-8866652;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6804757;Reactome: R-HSA-5689880 "Formation of TC-NER Pre-Incision Complex";"Regulation of PTEN localization";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Regulation of TP53 Degradation";"Ub-specific processing proteases" JAMg_model_559.3 16 Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72702 "L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition" JAMg_model_16528.2 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" JAMg_model_4972.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" JAMg_model_1174.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" JAMg_model_5776.1 3 Reactome: R-HSA-1614603;Reactome: R-HSA-2408508;Reactome: R-HSA-1614558 "Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine" JAMg_model_1116.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_2182.3 4 Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" JAMg_model_8336.2 3 Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-8939243 "Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" JAMg_model_18188.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" JAMg_model_10124.5 6 KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3;Reactome: R-HSA-1268020;KEGG: 00290+4.2.1.33;Reactome: R-HSA-71403;KEGG: 00020+4.2.1.3 "Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Mitochondrial protein import";"Valine, leucine and isoleucine biosynthesis";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)" JAMg_model_18090.6 3 Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" JAMg_model_4152.1 7 KEGG: 04070+3.1.3.36;KEGG: 00562+3.1.3.36;MetaCyc: PWY-6368;Reactome: R-HSA-8856828;Reactome: R-HSA-1855183;Reactome: R-HSA-1855204;Reactome: R-HSA-1660499 "Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Clathrin-mediated endocytosis";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol";"Synthesis of PIPs at the plasma membrane" JAMg_model_5690.4 2 Reactome: R-HSA-606279;Reactome: R-HSA-6783310 "Deposition of new CENPA-containing nucleosomes at the centromere";"Fanconi Anemia Pathway" JAMg_model_15441.3 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" JAMg_model_12597.1 10 Reactome: R-HSA-9639288;Reactome: R-HSA-381038;KEGG: 00195+7.1.2.2;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1799339;Reactome: R-HSA-1222556;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;Reactome: R-HSA-983712 "Amino acids regulate mTORC1";"XBP1(S) activates chaperone genes";"Photosynthesis";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"SRP-dependent cotranslational protein targeting to membrane";"ROS and RNS production in phagocytes";"ATP biosynthesis";"Oxidative phosphorylation";"Ion channel transport" JAMg_model_5212.2 4 MetaCyc: PWY-6482;Reactome: R-HSA-8849175;MetaCyc: PWY-7546;Reactome: R-HSA-5358493 "Diphthamide biosynthesis I (archaea)";"Threonine catabolism";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2" JAMg_model_4116.8 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" JAMg_model_19655.4 3 MetaCyc: PWY-7856;Reactome: R-HSA-189451;KEGG: 00860+2.5.1.141 "Heme a biosynthesis";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism" JAMg_model_5776.8 3 Reactome: R-HSA-1614558;Reactome: R-HSA-2408508;Reactome: R-HSA-1614603 "Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine" JAMg_model_9277.3 3 Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import" JAMg_model_6903.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156827 "Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression" JAMg_model_13791.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_10328.6 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" JAMg_model_299.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_10134.3 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" JAMg_model_2777.2 14 Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-203927 "Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis" JAMg_model_14919.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" JAMg_model_8760.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_2592.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_10992.6 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" JAMg_model_11691.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" JAMg_model_6290.1 3 KEGG: 00511+3.2.1.45;KEGG: 00600+3.2.1.45;Reactome: R-HSA-1660662 "Other glycan degradation";"Sphingolipid metabolism";"Glycosphingolipid metabolism" JAMg_model_20078.1 5 KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928;MetaCyc: PWY-6558;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253 "Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS" JAMg_model_2842.5 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_4583.1 7 Reactome: R-HSA-191273;MetaCyc: PWY-6074;KEGG: 00100+1.3.1.70;Reactome: R-HSA-9022692;MetaCyc: PWY-8026;MetaCyc: PWY-7154;MetaCyc: PWY-2541 "Cholesterol biosynthesis";"Zymosterol biosynthesis";"Steroid biosynthesis";"Regulation of MECP2 expression and activity";"Sterol biosynthesis (methylotrophs)";"Ergosterol biosynthesis II";"Phytosterol biosynthesis (plants)" JAMg_model_8917.1 9 MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52 "Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation" JAMg_model_2657.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" JAMg_model_12688.3 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_8468.2 3 Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691 "Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" JAMg_model_5924.6 3 Reactome: R-HSA-8951664;Reactome: R-HSA-349425;MetaCyc: PWY-7511 "Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Protein ubiquitination" JAMg_model_496.2 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" JAMg_model_19012.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" JAMg_model_16687.1 13 Reactome: R-HSA-2024101;Reactome: R-HSA-2022857;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52 "CS/DS degradation";"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation" JAMg_model_9577.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" JAMg_model_3469.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-5627123 "Clathrin-mediated endocytosis";"RHO GTPases activate PAKs" JAMg_model_9186.3 6 Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107 "Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" JAMg_model_4220.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" JAMg_model_17241.1 6 Reactome: R-HSA-8874081;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-3000171;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490 "MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Non-integrin membrane-ECM interactions";"Collagen chain trimerization";"Collagen degradation" JAMg_model_12705.1 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" JAMg_model_13649.2 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" JAMg_model_5094.1 7 Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus" JAMg_model_11146.1 2 KEGG: 00970+6.1.1.9;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" JAMg_model_9228.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Peptide chain elongation" JAMg_model_17118.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" JAMg_model_20034.1 14 Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121 "Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching";"Dual incision in TC-NER";"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI" JAMg_model_8159.4 12 MetaCyc: PWY-1861;MetaCyc: PWY-6142;Reactome: R-HSA-70171;KEGG: 00030+4.1.2.13;KEGG: 00051+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00680+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-5484;MetaCyc: PWY-1042 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Pentose phosphate pathway";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)" JAMg_model_19465.3 30 Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-917937;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-2122947;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-1170546;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-5684264;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-2565942;Reactome: R-HSA-195253;Reactome: R-HSA-2644607;Reactome: R-HSA-400253;Reactome: R-HSA-2894862;Reactome: R-HSA-5607764;Reactome: R-HSA-2644606;Reactome: R-HSA-69231 "Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Iron uptake and transport";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"NOTCH1 Intracellular Domain Regulates Transcription";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Prolactin receptor signaling";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"Regulation of PLK1 Activity at G2/M Transition";"Degradation of beta-catenin by the destruction complex";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Circadian Clock";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"CLEC7A (Dectin-1) signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Cyclin D associated events in G1" JAMg_model_12749.2 12 Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878 "Mitotic Prometaphase";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Separation of Sister Chromatids";"COPI-mediated anterograde transport" JAMg_model_15510.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" JAMg_model_14563.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" JAMg_model_12336.1 10 Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-2514853;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-191859;Reactome: R-HSA-1368082;Reactome: R-HSA-400253 "Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"Condensation of Prometaphase Chromosomes";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"snRNP Assembly";"RORA activates gene expression";"Circadian Clock" JAMg_model_6436.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" JAMg_model_20873.3 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_10062.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" JAMg_model_18918.3 3 Reactome: R-HSA-70268;MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5 "Pyruvate metabolism";"Methylglyoxal degradation I";"Pyruvate metabolism" JAMg_model_11953.1 15 Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-8986944 "Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2" JAMg_model_16707.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_19288.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" JAMg_model_19537.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-5972 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)" JAMg_model_21022.2 13 Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Viral mRNA Translation" JAMg_model_6843.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_15761.2 5 Reactome: R-HSA-1234176;Reactome: R-HSA-1234174;Reactome: R-HSA-8951664;Reactome: R-HSA-1234158;Reactome: R-HSA-8849473 "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cellular response to hypoxia";"Neddylation";"Regulation of gene expression by Hypoxia-inducible Factor";"PTK6 Expression" JAMg_model_13756.3 7 Reactome: R-HSA-381340;Reactome: R-HSA-2173796;Reactome: R-HSA-1989781;Reactome: R-HSA-2644606;Reactome: R-HSA-212436;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947 "Transcriptional regulation of white adipocyte differentiation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Generic Transcription Pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" JAMg_model_8069.1 10 Reactome: R-HSA-9018519;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-76042 "Estrogen-dependent gene expression";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance" JAMg_model_8122.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" JAMg_model_14022.2 1 Reactome: R-HSA-375276 "Peptide ligand-binding receptors" JAMg_model_8954.1 6 Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-2173788;Reactome: R-HSA-8863795 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Downregulation of TGF-beta receptor signaling";"Downregulation of ERBB2 signaling" JAMg_model_11500.3 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" JAMg_model_8481.3 2 Reactome: R-HSA-203927;Reactome: R-HSA-8986944 "MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2" JAMg_model_6953.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_21107.1 2 MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism" JAMg_model_7742.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" JAMg_model_18161.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" JAMg_model_13501.4 6 Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72689 "Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Formation of a pool of free 40S subunits" JAMg_model_1216.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_4351.2 1 Reactome: R-HSA-8949664 "Processing of SMDT1" JAMg_model_11027.2 3 MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65;Reactome: R-HSA-1483213 "Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PE" JAMg_model_8481.6 2 Reactome: R-HSA-8986944;Reactome: R-HSA-203927 "Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis" JAMg_model_12130.5 24 Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-9648025;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399 "COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"EML4 and NUDC in mitotic spindle formation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"HCMV Early Events";"Mitotic Prometaphase";"Kinesins";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Aggrephagy" JAMg_model_20154.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_12862.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" JAMg_model_10947.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" JAMg_model_18325.4 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" JAMg_model_5682.1 1 Reactome: R-HSA-3295583 "TRP channels" JAMg_model_2968.1 19 Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-8876725;Reactome: R-HSA-6790901;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-3214858 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Protein methylation";"rRNA modification in the nucleus and cytosol";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Peptide chain elongation";"RMTs methylate histone arginines" JAMg_model_12148.5 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" JAMg_model_11740.1 9 Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-6784531;Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-68962 "Polymerase switching";"Removal of the Flap Intermediate";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"tRNA processing in the nucleus";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex" JAMg_model_9493.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" JAMg_model_12986.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" JAMg_model_2248.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_12421.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_4429.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-8949215 "Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport" JAMg_model_10005.3 4 MetaCyc: PWY-8072;MetaCyc: PWY-8040;KEGG: 00473+5.1.1.1;MetaCyc: PWY-7383 "Alanine racemization";"Ansatrienin biosynthesis";"D-Alanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)" JAMg_model_9310.2 4 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;Reactome: R-HSA-2161541 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism" JAMg_model_7369.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" JAMg_model_10328.2 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" JAMg_model_7190.2 12 Reactome: R-HSA-193648;Reactome: R-HSA-416476;KEGG: 04926+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;Reactome: R-HSA-418885 "NRAGE signals death through JNK";"G alpha (q) signalling events";"Relaxin signaling pathway";"Rho GTPase cycle";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"DCC mediated attractive signaling" JAMg_model_7381.3 7 MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-7214 "Matairesinol biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)" JAMg_model_6267.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" JAMg_model_9617.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" JAMg_model_389.1 2 Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism" JAMg_model_9563.2 5 Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-389957 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC" JAMg_model_15291.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" JAMg_model_11112.1 27 Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638 "SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins" JAMg_model_12148.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" JAMg_model_17730.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" JAMg_model_13639.1 13 Reactome: R-HSA-3000178;Reactome: R-HSA-419037;Reactome: R-HSA-1442490;Reactome: R-HSA-216083;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320;Reactome: R-HSA-8948216;Reactome: R-HSA-3000171;Reactome: R-HSA-2022090;Reactome: R-HSA-1474244;Reactome: R-HSA-3000157;Reactome: R-HSA-186797;Reactome: R-HSA-2243919 "ECM proteoglycans";"NCAM1 interactions";"Collagen degradation";"Integrin cell surface interactions";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation";"Collagen chain trimerization";"Non-integrin membrane-ECM interactions";"Assembly of collagen fibrils and other multimeric structures";"Extracellular matrix organization";"Laminin interactions";"Signaling by PDGF";"Crosslinking of collagen fibrils" JAMg_model_7795.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" JAMg_model_6482.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" JAMg_model_11442.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" JAMg_model_11988.2 2 Reactome: R-HSA-171319;Reactome: R-HSA-6790901 "Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol" JAMg_model_9238.1 6 MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" JAMg_model_18125.2 9 KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52 "Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation" JAMg_model_3081.1 3 Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-5689880 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Ub-specific processing proteases" JAMg_model_6941.5 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" JAMg_model_17277.1 6 Reactome: R-HSA-71336;KEGG: 00040+5.1.3.1;MetaCyc: PWY-1861;KEGG: 00030+5.1.3.1;KEGG: 00710+5.1.3.1;MetaCyc: PWY-5723 "Pentose phosphate pathway";"Pentose and glucuronate interconversions";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Rubisco shunt" JAMg_model_5296.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" JAMg_model_13388.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" JAMg_model_21084.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" JAMg_model_8591.1 3 MetaCyc: PWY-8099;MetaCyc: PWY-7158;KEGG: 00790+4.2.1.96 "Tetrahydropteridine recycling";"L-phenylalanine degradation V";"Folate biosynthesis" JAMg_model_4284.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7035;Reactome: R-HSA-75876 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs" JAMg_model_10510.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" JAMg_model_7812.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" JAMg_model_5258.2 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" JAMg_model_3236.1 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" JAMg_model_18117.9 12 MetaCyc: PWY-6936;MetaCyc: PWY-1187;MetaCyc: PWY-601;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6309;KEGG: 00450+4.4.1.13;MetaCyc: PWY-2821;MetaCyc: PWY-801;Reactome: R-HSA-71240;MetaCyc: PWY-7901;MetaCyc: PWY-6842;KEGG: 00270+4.4.1.13 "Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from tryptophan";"Tryptophan metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Selenocompound metabolism";"Glucosinolate biosynthesis from phenylalanine";"Homocysteine and cysteine interconversion";"Tryptophan catabolism";"Glucosinolate biosynthesis from tyrosine";"Glutathione-mediated detoxification II";"Cysteine and methionine metabolism" JAMg_model_8935.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-532668 "DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" JAMg_model_6991.1 10 Reactome: R-HSA-9636383;Reactome: R-HSA-182971;Reactome: R-HSA-5689880;Reactome: R-HSA-9635644;Reactome: R-HSA-432720;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-917729;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Prevention of phagosomal-lysosomal fusion";"EGFR downregulation";"Ub-specific processing proteases";"Inhibition of membrane repair";"Lysosome Vesicle Biogenesis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" JAMg_model_18117.7 12 KEGG: 00380+2.6.1.7;MetaCyc: PWY-601;MetaCyc: PWY-6309;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6936;MetaCyc: PWY-1187;KEGG: 00270+4.4.1.13;MetaCyc: PWY-801;Reactome: R-HSA-71240;MetaCyc: PWY-7901;MetaCyc: PWY-2821;MetaCyc: PWY-6842 "Tryptophan metabolism";"Glucosinolate biosynthesis from tryptophan";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Selenocompound metabolism";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from homomethionine";"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion";"Tryptophan catabolism";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from phenylalanine";"Glutathione-mediated detoxification II" JAMg_model_18135.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" JAMg_model_6079.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" JAMg_model_5587.8 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" JAMg_model_1818.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_6808.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_14477.1 15 Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-8853884;Reactome: R-HSA-141430 "APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex" JAMg_model_11252.3 9 MetaCyc: PWY-7385;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;KEGG: 00564+1.1.1.8;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7902;MetaCyc: PWY-5667;MetaCyc: PWY-5981;MetaCyc: PWY-6118 "1,3-propanediol biosynthesis (engineered)";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Glycerol-3-phosphate shuttle" JAMg_model_16984.3 14 Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801 "Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching";"Dual incision in TC-NER";"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair" JAMg_model_11820.2 5 Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389960 "Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC" JAMg_model_551.4 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" JAMg_model_21130.4 6 Reactome: R-HSA-9033241;Reactome: R-HSA-9615017;KEGG: 00630+1.11.1.6;Reactome: R-HSA-6798695;Reactome: R-HSA-3299685;KEGG: 00380+1.11.1.6 "Peroxisomal protein import";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Glyoxylate and dicarboxylate metabolism";"Neutrophil degranulation";"Detoxification of Reactive Oxygen Species";"Tryptophan metabolism" JAMg_model_5069.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_10021.1 4 KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841;KEGG: 00053+1.13.99.1;Reactome: R-HSA-1855183 "Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Ascorbate and aldarate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol" JAMg_model_5574.4 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" JAMg_model_998.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" JAMg_model_10754.3 3 Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2 "VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway" JAMg_model_4597.1 5 Reactome: R-HSA-1442490;Reactome: R-HSA-1679131;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-2022090 "Collagen degradation";"Trafficking and processing of endosomal TLR";"MHC class II antigen presentation";"Neutrophil degranulation";"Assembly of collagen fibrils and other multimeric structures" JAMg_model_907.10 8 Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-3928665;Reactome: R-HSA-432720;Reactome: R-HSA-190873;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"EPH-ephrin mediated repulsion of cells";"Lysosome Vesicle Biogenesis";"Gap junction degradation";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" JAMg_model_3981.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" JAMg_model_4336.4 34 Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-9639288;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-168276 "Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Amino acids regulate mTORC1";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways" JAMg_model_20279.1 4 MetaCyc: PWY-5028;KEGG: 00340+3.5.2.7;MetaCyc: PWY-5030;Reactome: R-HSA-70921 "L-histidine degradation II";"Histidine metabolism";"L-histidine degradation III";"Histidine catabolism" JAMg_model_10696.1 57 Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-1169091;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-450408 "Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI2 by the proteasome";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Activation of NF-kappaB in B cells";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA" JAMg_model_17488.2 1 Reactome: R-HSA-611105 "Respiratory electron transport" JAMg_model_13997.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" JAMg_model_7648.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" JAMg_model_12446.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_19822.3 19 MetaCyc: PWY-6728;KEGG: 00680+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-7115;KEGG: 00630+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-5392;KEGG: 00020+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-7383;Reactome: R-HSA-70263;MetaCyc: PWY-5690;KEGG: 00710+1.1.1.37;MetaCyc: PWY-1622;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-5913;KEGG: 00270+1.1.1.37;KEGG: 00720+1.1.1.37 "Methylaspartate cycle";"Methane metabolism";"Pyruvate metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate and dicarboxylate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis";"TCA cycle II (plants and fungi)";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation I (serine pathway)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Cysteine and methionine metabolism";"Carbon fixation pathways in prokaryotes" JAMg_model_14663.2 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" JAMg_model_21109.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" JAMg_model_3194.1 3 MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546 "Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)" JAMg_model_9706.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" JAMg_model_8159.9 12 MetaCyc: PWY-5484;MetaCyc: PWY-1042;Reactome: R-HSA-70263;KEGG: 00010+4.1.2.13;KEGG: 00680+4.1.2.13;KEGG: 00710+4.1.2.13;KEGG: 00030+4.1.2.13;KEGG: 00051+4.1.2.13;MetaCyc: PWY-7385;Reactome: R-HSA-70171;MetaCyc: PWY-6142;MetaCyc: PWY-1861 "Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" JAMg_model_5560.1 2 MetaCyc: PWY-7560;KEGG: 00900+2.7.7.60 "Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis" JAMg_model_9176.1 3 Reactome: R-HSA-9033807;MetaCyc: PWY-7833;MetaCyc: PWY-7831 "ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide" JAMg_model_1772.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" JAMg_model_16579.3 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_625.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" JAMg_model_3870.3 2 Reactome: R-HSA-3065676;Reactome: R-HSA-3065678 "SUMO is conjugated to E1 (UBA2:SAE1)";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)" JAMg_model_9527.1 2 Reactome: R-HSA-1482798;Reactome: R-HSA-1268020 "Acyl chain remodeling of CL";"Mitochondrial protein import" JAMg_model_703.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" JAMg_model_8303.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_19084.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-159231 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript" JAMg_model_7182.2 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" JAMg_model_9717.1 4 Reactome: R-HSA-162699;Reactome: R-HSA-4719377;Reactome: R-HSA-4717374;Reactome: R-HSA-4719360 "Synthesis of dolichyl-phosphate mannose";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM3 causes DPM3-CDG (CDG-1o)" JAMg_model_1458.1 21 MetaCyc: PWY-7222;MetaCyc: PWY-7224;MetaCyc: PWY-7176;MetaCyc: PWY-7227;MetaCyc: PWY-7187;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.3;MetaCyc: PWY-6545;Reactome: R-HSA-499943;MetaCyc: PWY-7219;MetaCyc: PWY-7205;MetaCyc: PWY-7184;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7197;MetaCyc: PWY-7226;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7220;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.6;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7210 "Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" JAMg_model_5070.2 17 MetaCyc: PWY-7179-1;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6611;MetaCyc: PWY-6644;MetaCyc: PWY-7179;Reactome: R-HSA-74259;MetaCyc: PWY-5695;MetaCyc: PWY-6608;MetaCyc: PWY-6627;KEGG: 00760+2.4.2.1;KEGG: 00230+2.4.2.1;Reactome: R-HSA-6798695;Reactome: R-HSA-74217;MetaCyc: PWY-5532;MetaCyc: PWY-6620;MetaCyc: PWY-4202;MetaCyc: PWY-6609 "Purine deoxyribonucleosides degradation II";"Pyrimidine metabolism";"Adenine and adenosine salvage V";"Fluoroacetate and fluorothreonine biosynthesis";"Purine deoxyribonucleosides degradation I";"Purine catabolism";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation III";"Salinosporamide A biosynthesis";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Neutrophil degranulation";"Purine salvage";"Nucleoside and nucleotide degradation (archaea)";"Guanine and guanosine salvage";"Arsenate detoxification I (mammalian)";"Adenine and adenosine salvage III" JAMg_model_628.3 6 MetaCyc: PWY-5530;KEGG: 00053+3.1.1.17;KEGG: 00930+3.1.1.17;MetaCyc: PWY-2221;KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165 "Sorbitol biosynthesis II";"Ascorbate and aldarate metabolism";"Caprolactam degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)" JAMg_model_15147.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_2389.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" JAMg_model_18603.1 11 KEGG: 00240+3.1.3.5;KEGG: 00230+3.1.3.5;MetaCyc: PWY-6607;MetaCyc: PWY-5381;MetaCyc: PWY-6608;MetaCyc: PWY-7821;MetaCyc: PWY-5695;MetaCyc: PWY-6606;MetaCyc: PWY-6596;KEGG: 00760+3.1.3.5;MetaCyc: PWY-7185 "Pyrimidine metabolism";"Purine metabolism";"Guanosine nucleotides degradation I";"Pyridine nucleotide cycling (plants)";"Guanosine nucleotides degradation III";"Tunicamycin biosynthesis";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation II";"Adenosine nucleotides degradation I";"Nicotinate and nicotinamide metabolism";"UTP and CTP dephosphorylation I" JAMg_model_19742.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-1660661;Reactome: R-HSA-9609523 "Neutrophil degranulation";"Sphingolipid de novo biosynthesis";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" JAMg_model_3001.1 52 Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-174154;Reactome: R-HSA-5687128;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-69601;Reactome: R-HSA-4641257 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"APC/C:Cdc20 mediated degradation of Securin";"MAPK6/MAPK4 signaling";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"UCH proteinases";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN" JAMg_model_4497.1 5 Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-5250924 "RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression" JAMg_model_2588.2 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" JAMg_model_750.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" JAMg_model_8298.10 4 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-1912420 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi" JAMg_model_639.2 24 Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-9609736;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"Kinesins";"HCMV Early Events";"Mitotic Prometaphase";"Assembly and cell surface presentation of NMDA receptors";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion" JAMg_model_11657.4 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" JAMg_model_11904.2 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" JAMg_model_19531.1 9 MetaCyc: PWY-7769;MetaCyc: PWY-8067;MetaCyc: PWY-6322;KEGG: 00998+4.1.1.82;MetaCyc: PWY-6839;MetaCyc: PWY-6682;MetaCyc: PWY-7510;KEGG: 00440+4.1.1.82;MetaCyc: PWY-5757 "Phosalacine biosynthesis";"Methylphosphonate biosynthesis";"Phosphinothricin tripeptide biosynthesis";"Biosynthesis of various secondary metabolites - part 2";"2-aminoethylphosphonate biosynthesis";"Dehydrophos biosynthesis";"Rhizocticin A and B biosynthesis";"Phosphonate and phosphinate metabolism";"Fosfomycin biosynthesis" JAMg_model_4356.1 3 KEGG: 00510+2.4.1.265;Reactome: R-HSA-4724325;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" JAMg_model_5839.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" JAMg_model_3742.1 8 MetaCyc: PWY-5;MetaCyc: PWY-5154;MetaCyc: PWY-7400;KEGG: 00220+6.3.4.5;MetaCyc: PWY-4983;Reactome: R-HSA-70635;MetaCyc: PWY-4984;KEGG: 00250+6.3.4.5 "Canavanine biosynthesis";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"L-arginine biosynthesis IV (archaebacteria)";"Arginine biosynthesis";"Nitric oxide biosynthesis II (mammals)";"Urea cycle";"Urea cycle";"Alanine, aspartate and glutamate metabolism" JAMg_model_4874.3 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" JAMg_model_596.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_13339.3 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" JAMg_model_8210.2 6 Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702 "Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition" JAMg_model_7069.2 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_19013.2 7 Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;MetaCyc: PWY-7511 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Protein ubiquitination" JAMg_model_15154.4 1 KEGG: 00051+4.2.1.68 "Fructose and mannose metabolism" JAMg_model_451.1 4 Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-8953750;Reactome: R-HSA-69202 "Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Transcriptional Regulation by E2F6";"Cyclin E associated events during G1/S transition" JAMg_model_10566.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" JAMg_model_9236.3 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" JAMg_model_4582.2 7 MetaCyc: PWY-6074;Reactome: R-HSA-191273;KEGG: 00100+1.3.1.70;Reactome: R-HSA-9022692;MetaCyc: PWY-8026;MetaCyc: PWY-2541;MetaCyc: PWY-7154 "Zymosterol biosynthesis";"Cholesterol biosynthesis";"Steroid biosynthesis";"Regulation of MECP2 expression and activity";"Sterol biosynthesis (methylotrophs)";"Phytosterol biosynthesis (plants)";"Ergosterol biosynthesis II" JAMg_model_410.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" JAMg_model_11562.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" JAMg_model_2521.1 8 Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-68962 "Removal of the Flap Intermediate";"Polymerase switching";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex" JAMg_model_18625.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" JAMg_model_8702.2 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" JAMg_model_17588.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" JAMg_model_14872.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_6484.2 10 Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-3108214;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554 "Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" JAMg_model_11034.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" JAMg_model_5069.3 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_12749.4 12 Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-68877 "COPI-mediated anterograde transport";"Separation of Sister Chromatids";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"Mitotic Prometaphase" JAMg_model_6075.2 24 Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-5617833;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690;Reactome: R-HSA-68877 "RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"HCMV Early Events";"Mitotic Prometaphase" JAMg_model_1618.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" JAMg_model_10721.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" JAMg_model_16966.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" JAMg_model_7863.1 13 Reactome: R-HSA-71403;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5537;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-6969;MetaCyc: PWY-5913;MetaCyc: PWY-6728;MetaCyc: PWY-7384;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5538 "Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate VI" JAMg_model_8637.5 4 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.259+2.4.1.261;KEGG: 00513+2.4.1.261;Reactome: R-HSA-4720454 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)" JAMg_model_16624.4 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" JAMg_model_13456.3 2 Reactome: R-HSA-442982;Reactome: R-HSA-5673001 "Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade" JAMg_model_18278.1 4 Reactome: R-HSA-3899300;Reactome: R-HSA-9615710;Reactome: R-HSA-9613829;Reactome: R-HSA-9646399 "SUMOylation of transcription cofactors";"Late endosomal microautophagy";"Chaperone Mediated Autophagy";"Aggrephagy" JAMg_model_16858.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" JAMg_model_20806.1 1 Reactome: R-HSA-6798163 "Choline catabolism" JAMg_model_9186.5 6 MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism" JAMg_model_13997.2 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" JAMg_model_14776.5 2 Reactome: R-HSA-909733;Reactome: R-HSA-8983711 "Interferon alpha/beta signaling";"OAS antiviral response" JAMg_model_19174.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" JAMg_model_10892.3 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" JAMg_model_6044.1 7 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection" JAMg_model_5653.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" JAMg_model_1639.3 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_11252.5 9 MetaCyc: PWY-6118;MetaCyc: PWY-5981;MetaCyc: PWY-5667;MetaCyc: PWY-7902;KEGG: 00564+1.1.1.8;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7385;MetaCyc: PWY-7411;Reactome: R-HSA-1483166 "Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Glucosylglycerol biosynthesis";"Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA" JAMg_model_11411.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" JAMg_model_13381.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" JAMg_model_19852.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_7883.2 1 Reactome: R-HSA-2565942 "Regulation of PLK1 Activity at G2/M Transition" JAMg_model_3663.3 5 KEGG: 00983+2.7.1.21;Reactome: R-HSA-73614;Reactome: R-HSA-69205;MetaCyc: PWY-7199;KEGG: 00240+2.7.1.21 "Drug metabolism - other enzymes";"Pyrimidine salvage";"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine metabolism" JAMg_model_460.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_18048.8 5 KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;MetaCyc: PWY-5514;Reactome: R-HSA-70171;MetaCyc: PWY-6906 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis";"Chitin derivatives degradation" JAMg_model_1693.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" JAMg_model_8211.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_15095.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" JAMg_model_3074.2 2 Reactome: R-HSA-8873719;Reactome: R-HSA-6803205 "RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain" JAMg_model_3198.4 1 Reactome: R-HSA-1483191 "Synthesis of PC" JAMg_model_10417.4 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" JAMg_model_11705.4 6 Reactome: R-HSA-73817;KEGG: 00230+4.1.1.21;MetaCyc: PWY-7234;MetaCyc: PWY-6124;MetaCyc: PWY-6123;KEGG: 00230+6.3.2.6 "Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism" JAMg_model_15765.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" JAMg_model_8827.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" JAMg_model_19183.1 5 KEGG: 00790+1.5.1.3;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.3;MetaCyc: PWY-3841;MetaCyc: PWY-6614 "Folate biosynthesis";"Metabolism of folate and pterines";"One carbon pool by folate";"Folate transformations II (plants)";"Tetrahydrofolate biosynthesis" JAMg_model_17409.1 5 MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14 "Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism" JAMg_model_12555.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" JAMg_model_10993.1 3 Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification" JAMg_model_4987.3 29 Reactome: R-HSA-912446;Reactome: R-HSA-3371511;Reactome: R-HSA-3108214;Reactome: R-HSA-5685938;Reactome: R-HSA-5696395;Reactome: R-HSA-3371453;Reactome: R-HSA-6804756;Reactome: R-HSA-110314;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-6783310;Reactome: R-HSA-6782135;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-68962;Reactome: R-HSA-174437;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-176187;Reactome: R-HSA-69166 "Meiotic recombination";"HSF1 activation";"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)";"Formation of Incision Complex in GG-NER";"Regulation of HSF1-mediated heat shock response";"Regulation of TP53 Activity through Phosphorylation";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Fanconi Anemia Pathway";"Dual incision in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of ATR in response to replication stress";"Removal of the Flap Intermediate" JAMg_model_16891.2 1 Reactome: R-HSA-74217 "Purine salvage" JAMg_model_10417.2 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" JAMg_model_8897.2 3 Reactome: R-HSA-1268020;Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Mitochondrial protein import";"Respiratory electron transport";"Complex I biogenesis" JAMg_model_20738.5 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_361.8 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" JAMg_model_13054.2 3 KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" JAMg_model_12752.2 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" JAMg_model_18327.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" JAMg_model_20404.3 10 MetaCyc: PWY-7003;Reactome: R-HSA-70171;MetaCyc: PWY-6142;KEGG: 00051+5.3.1.1;MetaCyc: PWY-1042;KEGG: 00710+5.3.1.1;KEGG: 00562+5.3.1.1;MetaCyc: PWY-5484;Reactome: R-HSA-70263;KEGG: 00010+5.3.1.1 "Glycerol degradation to butanol";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Inositol phosphate metabolism";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis" JAMg_model_4522.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" JAMg_model_13624.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394 "Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER" JAMg_model_16085.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" JAMg_model_1372.1 9 Reactome: R-HSA-2022928;Reactome: R-HSA-2024096;Reactome: R-HSA-975634;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-3656237;Reactome: R-HSA-4420332;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801 "HS-GAG biosynthesis";"HS-GAG degradation";"Retinoid metabolism and transport";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT2 causes exostoses 2";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD" JAMg_model_715.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" JAMg_model_957.5 4 Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases activate KTN1";"Kinesins" JAMg_model_13756.1 7 Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-212436;Reactome: R-HSA-2173796;Reactome: R-HSA-1989781;Reactome: R-HSA-2644606;Reactome: R-HSA-381340 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Generic Transcription Pathway";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Transcriptional regulation of white adipocyte differentiation" JAMg_model_1696.2 9 Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-69205;Reactome: R-HSA-69183 "DNA replication initiation";"Polymerase switching";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"G1/S-Specific Transcription";"Processive synthesis on the lagging strand" JAMg_model_19749.1 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_17734.5 5 KEGG: 00860+4.2.1.24;MetaCyc: PWY-5188;Reactome: R-HSA-6798695;MetaCyc: PWY-5189;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Neutrophil degranulation";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis" JAMg_model_16788.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" JAMg_model_12219.2 5 Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5689901;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565 "Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Metalloprotease DUBs";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" JAMg_model_11506.1 1 Reactome: R-HSA-5624138 "Trafficking of myristoylated proteins to the cilium" JAMg_model_20430.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" JAMg_model_5849.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-6433 "Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)" JAMg_model_6042.3 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" JAMg_model_4213.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_7424.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_11904.6 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" JAMg_model_3438.6 3 Reactome: R-HSA-2129379;Reactome: R-HSA-1566948;Reactome: R-HSA-1474228 "Molecules associated with elastic fibres";"Elastic fibre formation";"Degradation of the extracellular matrix" JAMg_model_10124.7 6 Reactome: R-HSA-71403;KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3;KEGG: 00720+4.2.1.3;Reactome: R-HSA-1268020;KEGG: 00630+4.2.1.3 "Citric acid cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Mitochondrial protein import";"Glyoxylate and dicarboxylate metabolism" JAMg_model_6699.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_19162.3 1 Reactome: R-HSA-163560 "Triglyceride catabolism" JAMg_model_19028.2 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_13194.1 4 Reactome: R-HSA-70895;MetaCyc: PWY-5642;KEGG: 00640+1.2.1.27;KEGG: 00280+1.2.1.27 "Branched-chain amino acid catabolism";"2,4-dinitrotoluene degradation";"Propanoate metabolism";"Valine, leucine and isoleucine degradation" JAMg_model_5112.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_15216.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" JAMg_model_13244.4 7 KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2;Reactome: R-HSA-5628897;Reactome: R-HSA-210500;MetaCyc: PWY-5921 "Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"TP53 Regulates Metabolic Genes";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation" JAMg_model_2053.3 2 KEGG: 00030+1.1.1.47;Reactome: R-HSA-71384 "Pentose phosphate pathway";"Ethanol oxidation" JAMg_model_1137.1 10 MetaCyc: PWY-8001;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-6842;MetaCyc: PWY-7559;MetaCyc: PWY-4041;MetaCyc: PWY-7112 "Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification" JAMg_model_9797.7 14 Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-191273;Reactome: R-HSA-156902 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Cholesterol biosynthesis";"Peptide chain elongation" JAMg_model_17319.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" JAMg_model_8815.1 7 MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7 "Sesamin biosynthesis";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis" JAMg_model_12508.5 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" JAMg_model_10500.2 5 Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823 "mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex" JAMg_model_21305.1 14 KEGG: 00630+2.1.2.1;KEGG: 00680+2.1.2.1;KEGG: 00460+2.1.2.1;MetaCyc: PWY-3841;Reactome: R-HSA-196757;MetaCyc: PWY-181;MetaCyc: PWY-3661;MetaCyc: PWY-3661-1;MetaCyc: PWY-2161;KEGG: 00260+2.1.2.1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-5497;MetaCyc: PWY-1622;MetaCyc: PWY-2201 "Glyoxylate and dicarboxylate metabolism";"Methane metabolism";"Cyanoamino acid metabolism";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Photorespiration ";"Glycine betaine degradation I";"Glycine betaine degradation II (mammalian)";"Folate polyglutamylation";"Glycine, serine and threonine metabolism";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Formaldehyde assimilation I (serine pathway)";"Folate transformations I" JAMg_model_6409.2 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_6589.3 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" JAMg_model_17165.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" JAMg_model_7576.3 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" JAMg_model_6735.1 2 Reactome: R-HSA-3108214;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination" JAMg_model_907.4 8 Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-432720;Reactome: R-HSA-190873;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"Lysosome Vesicle Biogenesis";"Gap junction degradation";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" JAMg_model_3075.2 52 Reactome: R-HSA-73762;Reactome: R-HSA-76066;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-76071;Reactome: R-HSA-167242;Reactome: R-HSA-75953;Reactome: R-HSA-6782135;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-6803529;Reactome: R-HSA-76042;Reactome: R-HSA-5601884;Reactome: R-HSA-72203;Reactome: R-HSA-5250924;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-76061;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-9018519;Reactome: R-HSA-73780;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-203927;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-6807505;Reactome: R-HSA-6781827;Reactome: R-HSA-168325;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167160;Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-749476;Reactome: R-HSA-72163;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-167238;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-8851708;Reactome: R-HSA-5617472;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-72165 "RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation";"Dual incision in TC-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"PIWI-interacting RNA (piRNA) biogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"B-WICH complex positively regulates rRNA expression";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Estrogen-dependent gene expression";"RNA Polymerase III Chain Elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"MicroRNA (miRNA) biogenesis";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA polymerase II transcribes snRNA genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Viral Messenger RNA Synthesis";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"RNA Polymerase III Abortive And Retractive Initiation";"mRNA Splicing - Major Pathway";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Signaling by FGFR2 IIIa TM";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway" JAMg_model_13632.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" JAMg_model_1600.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_16828.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" JAMg_model_17189.2 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" JAMg_model_19918.1 1 Reactome: R-HSA-5627083 "RHO GTPases regulate CFTR trafficking" JAMg_model_13583.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_19368.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" JAMg_model_20787.3 32 Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-168325;Reactome: R-HSA-6807505;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-167172;Reactome: R-HSA-8851708;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-9018519;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-72203;Reactome: R-HSA-76042;Reactome: R-HSA-6803529 "mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Viral Messenger RNA Synthesis";"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"Transcription of the HIV genome";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Estrogen-dependent gene expression";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"FGFR2 alternative splicing" JAMg_model_19631.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_11565.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "MHC class II antigen presentation";"Neutrophil degranulation";"COPII-mediated vesicle transport";"Cargo concentration in the ER" JAMg_model_8910.7 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" JAMg_model_15064.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_11259.1 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" JAMg_model_3198.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" JAMg_model_3366.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-8869496 "rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" JAMg_model_20280.1 2 Reactome: R-HSA-6804756;Reactome: R-HSA-8854518 "Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2" JAMg_model_4474.1 6 MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23 "Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Galactose metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism" JAMg_model_359.4 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" JAMg_model_10744.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_2014.2 5 KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;MetaCyc: PWY-5381;Reactome: R-HSA-197264 "Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging" JAMg_model_5269.1 4 KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219 "Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis" JAMg_model_16735.1 7 Reactome: R-HSA-203927;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-1655829;Reactome: R-HSA-6784531 "MicroRNA (miRNA) biogenesis";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"tRNA processing in the nucleus" JAMg_model_2764.5 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" JAMg_model_4349.1 8 Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-165054;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Rev-mediated nuclear export of HIV RNA";"Resolution of Sister Chromatid Cohesion" JAMg_model_19039.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-8866654;Reactome: R-HSA-110314 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins";"Recognition of DNA damage by PCNA-containing replication complex" JAMg_model_1147.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" JAMg_model_13657.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" JAMg_model_14247.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_8009.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_2002.4 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" JAMg_model_19822.4 19 KEGG: 00720+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-6969;Reactome: R-HSA-71403;KEGG: 00710+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-5690;Reactome: R-HSA-70263;MetaCyc: PWY-7383;MetaCyc: PWY-561;KEGG: 00020+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-8086;KEGG: 00630+1.1.1.37;MetaCyc: PWY-7115;KEGG: 00620+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-6728 "Carbon fixation pathways in prokaryotes";"Cysteine and methionine metabolism";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation I (serine pathway)";"TCA cycle II (plants and fungi)";"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Glyoxylate and dicarboxylate metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Pyruvate metabolism";"Methane metabolism";"Methylaspartate cycle" JAMg_model_2436.1 8 MetaCyc: PWY-6556;Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00983+3.5.4.5;KEGG: 00240+3.5.4.5;Reactome: R-HSA-6798695;MetaCyc: PWY-7199;MetaCyc: PWY-7181 "Pyrimidine ribonucleosides salvage II";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Neutrophil degranulation";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleosides degradation" JAMg_model_15810.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" JAMg_model_13397.5 7 Reactome: R-HSA-1483191;MetaCyc: PWY-7782;MetaCyc: PWY-3385;Reactome: R-HSA-1483213;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7886;MetaCyc: PWY-7818 "Synthesis of PC";"Plasmalogen biosynthesis";"Choline biosynthesis I";"Synthesis of PE";"Glycerophospholipid metabolism";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)" JAMg_model_11649.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" JAMg_model_12350.1 7 KEGG: 00240+6.3.5.5;MetaCyc: PWY-5154;MetaCyc: PWY-7791;MetaCyc: PWY-7790;MetaCyc: PWY-7400;KEGG: 00250+6.3.5.5;MetaCyc: PWY-5686 "Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"UMP biosynthesis III";"UMP biosynthesis II";"L-arginine biosynthesis IV (archaebacteria)";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis I" JAMg_model_16422.1 6 Reactome: R-HSA-416993;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900;Reactome: R-HSA-114516;Reactome: R-HSA-76005 "Trafficking of GluR2-containing AMPA receptors";"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+" JAMg_model_18194.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_11904.4 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" JAMg_model_11342.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" JAMg_model_10324.1 32 Reactome: R-HSA-73776;Reactome: R-HSA-167242;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-72203;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-6803529;Reactome: R-HSA-76042;Reactome: R-HSA-167160;Reactome: R-HSA-72163;Reactome: R-HSA-6807505;Reactome: R-HSA-168325;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-167238 "RNA Polymerase II Promoter Escape";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes";"Viral Messenger RNA Synthesis";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation" JAMg_model_7617.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_5174.1 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_10191.3 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" JAMg_model_15583.2 19 Reactome: R-HSA-3000484;Reactome: R-HSA-3000471;Reactome: R-HSA-8856825;Reactome: R-HSA-8964026;Reactome: R-HSA-8856828;Reactome: R-HSA-8957275;Reactome: R-HSA-3000480;Reactome: R-HSA-202733;Reactome: R-HSA-8964038;Reactome: R-HSA-5686938;Reactome: R-HSA-381426;Reactome: R-HSA-432142;Reactome: R-HSA-975634;Reactome: R-HSA-8866423;Reactome: R-HSA-8963888;Reactome: R-HSA-8964041;Reactome: R-HSA-8964046;Reactome: R-HSA-3000497;Reactome: R-HSA-8963901 "Scavenging by Class F Receptors";"Scavenging by Class B Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron clearance";"Clathrin-mediated endocytosis";"Post-translational protein phosphorylation";"Scavenging by Class A Receptors";"Cell surface interactions at the vascular wall";"LDL clearance";"Regulation of TLR by endogenous ligand";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Platelet sensitization by LDL";"Retinoid metabolism and transport";"VLDL assembly";"Chylomicron assembly";"LDL remodeling";"VLDL clearance";"Scavenging by Class H Receptors";"Chylomicron remodeling" JAMg_model_5084.2 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" JAMg_model_7429.1 1 Reactome: R-HSA-196836 "Vitamin C (ascorbate) metabolism" JAMg_model_17313.1 1 Reactome: R-HSA-400253 "Circadian Clock" JAMg_model_2885.2 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" JAMg_model_578.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_2434.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_21261.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-194840 "RAB GEFs exchange GTP for GDP on RABs";"Rho GTPase cycle" JAMg_model_9060.1 4 Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" JAMg_model_14897.1 7 Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-380972 "mTOR signalling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Macroautophagy";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK" JAMg_model_14932.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" JAMg_model_18918.4 3 MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268 "Methylglyoxal degradation I";"Pyruvate metabolism";"Pyruvate metabolism" JAMg_model_17807.1 1 Reactome: R-HSA-6798163 "Choline catabolism" JAMg_model_9767.1 6 MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism" JAMg_model_21364.1 4 Reactome: R-HSA-2214320;Reactome: R-HSA-1650814;Reactome: R-HSA-1474228;Reactome: R-HSA-2243919 "Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes";"Degradation of the extracellular matrix";"Crosslinking of collagen fibrils" JAMg_model_8159.8 12 MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-7385;KEGG: 00051+4.1.2.13;KEGG: 00030+4.1.2.13;KEGG: 00710+4.1.2.13;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-1861;MetaCyc: PWY-6142 "Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" JAMg_model_16983.1 4 Reactome: R-HSA-77075;Reactome: R-HSA-167160;MetaCyc: PWY-7375;Reactome: R-HSA-72086 "RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I";"mRNA Capping" JAMg_model_2392.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" JAMg_model_8646.1 10 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-437239;KEGG: 05170+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-442742;KEGG: 05163+2.7.11.1 "Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Recycling pathway of L1";"Human immunodeficiency virus 1 infection";"RSK activation";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Human cytomegalovirus infection" JAMg_model_8476.2 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" JAMg_model_18152.2 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_10263.4 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" JAMg_model_7643.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation" JAMg_model_18324.2 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" JAMg_model_13380.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" JAMg_model_1248.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" JAMg_model_10417.3 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" JAMg_model_1545.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" JAMg_model_12833.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" JAMg_model_11411.4 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" JAMg_model_1876.2 11 Reactome: R-HSA-1227986;Reactome: R-HSA-8863795;Reactome: R-HSA-1250196;Reactome: R-HSA-8847993;Reactome: R-HSA-9664565;Reactome: R-HSA-6785631;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-1963642 "Signaling by ERBB2";"Downregulation of ERBB2 signaling";"SHC1 events in ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2 KD Mutants";"ERBB2 Regulates Cell Motility";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K events in ERBB2 signaling" JAMg_model_9298.2 6 Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660516;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1855183 "Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol" JAMg_model_2014.1 5 Reactome: R-HSA-197264;MetaCyc: PWY-5381;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695 "Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation" JAMg_model_3466.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_8993.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" JAMg_model_11554.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" JAMg_model_525.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" JAMg_model_11008.2 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" JAMg_model_957.3 4 Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases activate KTN1";"Kinesins" JAMg_model_14520.1 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" JAMg_model_11521.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" JAMg_model_18418.3 3 Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-72165 "snRNP Assembly";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" JAMg_model_11566.1 4 Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695 "Cargo concentration in the ER";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Neutrophil degranulation" JAMg_model_7655.5 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" JAMg_model_2002.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" JAMg_model_9518.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" JAMg_model_21295.2 7 MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-7214 "Matairesinol biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)" JAMg_model_20514.1 3 KEGG: 00860+1.16.3.1;Reactome: R-HSA-1362409;Reactome: R-HSA-1268020 "Porphyrin and chlorophyll metabolism";"Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import" JAMg_model_4235.2 6 MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23 "Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Galactose metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism" JAMg_model_19415.1 2 MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4 "Cellulose degradation II (fungi)";"Starch and sucrose metabolism" JAMg_model_9539.1 37 KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693607;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;MetaCyc: PWY-4661;MetaCyc: PWY-6372;Reactome: R-HSA-6804757;Reactome: R-HSA-6803207;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;MetaCyc: PWY-6664;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5693548;Reactome: R-HSA-6803204;KEGG: 00562+5.5.1.4;Reactome: R-HSA-5693579;Reactome: R-HSA-2559586;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;MetaCyc: PWY-6580;MetaCyc: PWY-2301;Reactome: R-HSA-6804760;Reactome: R-HSA-912446;Reactome: R-HSA-1855183;Reactome: R-HSA-349425;Reactome: R-HSA-69541;Reactome: R-HSA-3371453;Reactome: R-HSA-5685938;KEGG: 00521+5.5.1.4 "Relaxin signaling pathway";"Processing of DNA double-strand break ends";"Human papillomavirus infection";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Regulation of TP53 Degradation";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Human cytomegalovirus infection";"TP53 Regulates Transcription of DNA Repair Genes";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Di-myo-inositol phosphate biosynthesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Sensing of DNA Double Strand Breaks";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Inositol phosphate metabolism";"Homologous DNA Pairing and Strand Exchange";"DNA Damage/Telomere Stress Induced Senescence";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Phosphatidylinositol biosynthesis I (bacteria)";"Myo-inositol biosynthesis";"Regulation of TP53 Activity through Methylation";"Meiotic recombination";"Synthesis of IP2, IP, and Ins in the cytosol";"Autodegradation of the E3 ubiquitin ligase COP1";"Stabilization of p53";"Regulation of HSF1-mediated heat shock response";"HDR through Single Strand Annealing (SSA)";"Streptomycin biosynthesis" JAMg_model_14163.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-6804756 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation" JAMg_model_10408.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-8876198 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs" JAMg_model_10512.1 10 KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-7559;MetaCyc: PWY-6842;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2 "Glutathione metabolism";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism" JAMg_model_17158.1 40 Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167162;Reactome: R-HSA-9018519;Reactome: R-HSA-6803529;Reactome: R-HSA-5601884;Reactome: R-HSA-76042;Reactome: R-HSA-72203;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-6782135;Reactome: R-HSA-73776;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-75953;Reactome: R-HSA-77075;Reactome: R-HSA-5617472;Reactome: R-HSA-167172;Reactome: R-HSA-8851708;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-168325;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-72163;Reactome: R-HSA-5578749;Reactome: R-HSA-203927;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Estrogen-dependent gene expression";"FGFR2 alternative splicing";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"Dual incision in TC-NER";"RNA Polymerase II Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcription of the HIV genome";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Viral Messenger RNA Synthesis";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Major Pathway";"Transcriptional regulation by small RNAs";"MicroRNA (miRNA) biogenesis";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex" JAMg_model_13595.1 8 Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68689 "Orc1 removal from chromatin";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex" JAMg_model_9685.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_2692.2 15 MetaCyc: PWY-4983;MetaCyc: PWY-6824;KEGG: 00250+4.3.2.1;MetaCyc: PWY-5461;MetaCyc: PWY-4984;Reactome: R-HSA-70635;MetaCyc: PWY-5466;MetaCyc: PWY-5;MetaCyc: PWY-5154;MetaCyc: PWY-5469;MetaCyc: PWY-7400;KEGG: 00940+1.11.1.7;KEGG: 00220+4.3.2.1;MetaCyc: PWY-7445;MetaCyc: PWY-7214 "Nitric oxide biosynthesis II (mammals)";"Justicidin B biosynthesis";"Alanine, aspartate and glutamate metabolism";"Betanidin degradation";"Urea cycle";"Urea cycle";"Matairesinol biosynthesis";"Canavanine biosynthesis";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Sesamin biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"Phenylpropanoid biosynthesis";"Arginine biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)" JAMg_model_6942.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" JAMg_model_8160.3 12 Reactome: R-HSA-70263;KEGG: 00010+4.1.2.13;KEGG: 00710+4.1.2.13;KEGG: 00680+4.1.2.13;KEGG: 00030+4.1.2.13;KEGG: 00051+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-1861;Reactome: R-HSA-70171 "Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Pentose phosphate pathway";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis" JAMg_model_12303.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_15098.1 18 MetaCyc: PWY-7417;Reactome: R-HSA-1482922;Reactome: R-HSA-1482925;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482839;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-6803;Reactome: R-HSA-1482801;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783 "Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PA";"Acyl chain remodelling of PE";"Ether lipid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PS";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Plasmalogen degradation" JAMg_model_997.2 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" JAMg_model_17234.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" JAMg_model_1644.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" JAMg_model_10600.2 14 Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-426486;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593 "Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"Small interfering RNA (siRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity" JAMg_model_6068.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" JAMg_model_14663.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" JAMg_model_21250.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" JAMg_model_20578.1 5 MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" JAMg_model_6504.1 1 Reactome: R-HSA-5250924 "B-WICH complex positively regulates rRNA expression" JAMg_model_6360.4 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" JAMg_model_18725.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" JAMg_model_3505.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" JAMg_model_13539.3 7 Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-3214842;Reactome: R-HSA-3214815;Reactome: R-HSA-983231;Reactome: R-HSA-8943724;Reactome: R-HSA-5625886 "Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDMs demethylate histones";"HDACs deacetylate histones";"Factors involved in megakaryocyte development and platelet production";"Regulation of PTEN gene transcription";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3" JAMg_model_12129.2 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" JAMg_model_17160.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" JAMg_model_18888.1 6 MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis" JAMg_model_13288.1 4 Reactome: R-HSA-6802952;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-1632852 "Signaling by BRAF and RAF fusions";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Macroautophagy" JAMg_model_20861.2 6 Reactome: R-HSA-73930;Reactome: R-HSA-110357;Reactome: R-HSA-110362;Reactome: R-HSA-73933;Reactome: R-HSA-110373;Reactome: R-HSA-5651801 "Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Displacement of DNA glycosylase by APEX1";"POLB-Dependent Long Patch Base Excision Repair";"Resolution of Abasic Sites (AP sites)";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair" JAMg_model_18340.1 9 KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52 "Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism" JAMg_model_10745.3 5 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-72165 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"mRNA Splicing - Minor Pathway" JAMg_model_20146.1 3 MetaCyc: PWY-5963;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.9 "Thio-molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" JAMg_model_10083.2 4 MetaCyc: PWY-5030;Reactome: R-HSA-70921;KEGG: 00340+3.5.2.7;MetaCyc: PWY-5028 "L-histidine degradation III";"Histidine catabolism";"Histidine metabolism";"L-histidine degradation II" JAMg_model_21315.4 15 MetaCyc: PWY-7003;Reactome: R-HSA-70171;MetaCyc: PWY-6142;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7218;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-7383;KEGG: 00230+2.7.1.40;MetaCyc: PWY-5723;MetaCyc: PWY-2221;MetaCyc: PWY-8004;MetaCyc: PWY-6886 "Glycerol degradation to butanol";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pyruvate metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Purine metabolism";"Rubisco shunt";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)" JAMg_model_8476.3 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" JAMg_model_1116.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_15438.3 17 Reactome: R-HSA-9645460;Reactome: R-HSA-975163;Reactome: R-HSA-5689880;Reactome: R-HSA-450321;Reactome: R-HSA-937072;Reactome: R-HSA-168638;Reactome: R-HSA-5607764;Reactome: R-HSA-4086398;Reactome: R-HSA-445989;Reactome: R-HSA-937042;Reactome: R-HSA-9014325;Reactome: R-HSA-450302;Reactome: R-HSA-1169091;Reactome: R-HSA-5357956;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-202424 "Alpha-protein kinase 1 signaling pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Ub-specific processing proteases";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"NOD1/2 Signaling Pathway";"CLEC7A (Dectin-1) signaling";"Ca2+ pathway";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"IRAK2 mediated activation of TAK1 complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"activated TAK1 mediates p38 MAPK activation";"Activation of NF-kappaB in B cells";"TNFR1-induced NFkappaB signaling pathway";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"Downstream TCR signaling" JAMg_model_20172.2 9 KEGG: 04070+3.1.4.11;Reactome: R-HSA-112043;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;Reactome: R-HSA-416476;MetaCyc: PWY-6351;MetaCyc: PWY-8052 "Phosphatidylinositol signaling system";"PLC beta mediated events";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis" JAMg_model_107.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" JAMg_model_14812.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_3586.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" JAMg_model_5689.6 2 Reactome: R-HSA-191859;Reactome: R-HSA-6807505 "snRNP Assembly";"RNA polymerase II transcribes snRNA genes" JAMg_model_4688.3 8 KEGG: 00240+2.7.4.9;MetaCyc: PWY-7197;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-6545;Reactome: R-HSA-499943;MetaCyc: PWY-7187;MetaCyc: PWY-7198 "Pyrimidine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" JAMg_model_1775.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" JAMg_model_19591.1 2 Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13 "Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system" JAMg_model_20451.1 5 MetaCyc: PWY-7177;MetaCyc: PWY-7185;Reactome: R-HSA-499943;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7176 "UTP and CTP dephosphorylation II";"UTP and CTP dephosphorylation I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis" JAMg_model_1056.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" JAMg_model_7537.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" JAMg_model_2273.3 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" JAMg_model_17252.3 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" JAMg_model_16806.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" JAMg_model_17631.1 6 Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"Ca2+ pathway";"RUNX3 regulates WNT signaling" JAMg_model_5345.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" JAMg_model_6044.2 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection" JAMg_model_19551.1 6 KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;MetaCyc: PWY-7920 "Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)" JAMg_model_21106.1 2 KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281 "Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" JAMg_model_20624.2 3 Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.25;Reactome: R-HSA-8853383 "Neutrophil degranulation";"Other glycan degradation";"Lysosomal oligosaccharide catabolism" JAMg_model_7565.1 3 KEGG: 00860+2.5.1.17;Reactome: R-HSA-196741;Reactome: R-HSA-3359471 "Porphyrin and chlorophyll metabolism";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMAB causes methylmalonic aciduria type cblB" JAMg_model_20873.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_767.1 11 Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568 "G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates" JAMg_model_18430.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823 "Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex" JAMg_model_639.5 24 Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-5617833 "Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"HCMV Early Events";"Mitotic Prometaphase";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Kinesins";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly" JAMg_model_308.2 2 Reactome: R-HSA-1660661;Reactome: R-HSA-6798695 "Sphingolipid de novo biosynthesis";"Neutrophil degranulation" JAMg_model_12757.3 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" JAMg_model_15081.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" JAMg_model_6553.1 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_15882.1 3 Reactome: R-HSA-8875656;Reactome: R-HSA-8856828;Reactome: R-HSA-8854214 "MET receptor recycling";"Clathrin-mediated endocytosis";"TBC/RABGAPs" JAMg_model_17580.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" JAMg_model_20041.1 4 Reactome: R-HSA-1971475;KEGG: 00532+2.4.2.26;KEGG: 00534+2.4.2.26;MetaCyc: PWY-6557 "A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Glycosaminoglycan-protein linkage region biosynthesis" JAMg_model_480.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" JAMg_model_2735.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" JAMg_model_11736.1 4 KEGG: 00970+6.1.1.17;Reactome: R-HSA-379726;MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism" JAMg_model_12764.2 16 Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Peptide chain elongation" JAMg_model_9134.2 2 Reactome: R-HSA-446203;Reactome: R-HSA-1799339 "Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane" JAMg_model_4265.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_6807.2 5 KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3;KEGG: 00720+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00630+4.2.1.3 "Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Iron uptake and transport";"Glyoxylate and dicarboxylate metabolism" JAMg_model_5803.1 12 KEGG: 00630+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-5108;KEGG: 00620+6.2.1.1;MetaCyc: PWY-7118;KEGG: 00720+6.2.1.1;KEGG: 00680+6.2.1.1;MetaCyc: PWY-6672;MetaCyc: PWY-5132;MetaCyc: PWY-5133;MetaCyc: PWY-7857;KEGG: 00010+6.2.1.1 "Glyoxylate and dicarboxylate metabolism";"Propanoate metabolism";"L-isoleucine biosynthesis V";"Pyruvate metabolism";"Chitin degradation to ethanol";"Carbon fixation pathways in prokaryotes";"Methane metabolism";"Cis-genanyl-coa degradation";"Lupulone and humulone biosynthesis";"Colupulone and cohumulone biosynthesis";"Adlupulone and adhumulone biosynthesis";"Glycolysis / Gluconeogenesis" JAMg_model_6480.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" JAMg_model_8910.2 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" JAMg_model_12043.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" JAMg_model_10506.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" JAMg_model_2591.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_19707.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1660662 "Neutrophil degranulation";"Glycosphingolipid metabolism" JAMg_model_1677.1 8 KEGG: 00564+3.1.3.27;Reactome: R-HSA-1483148;MetaCyc: PWY-5668;KEGG: 04658+3.1.3.16;MetaCyc: PWY-5269;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;MetaCyc: PWY-7817 "Glycerophospholipid metabolism";"Synthesis of PG";"Cardiolipin biosynthesis I";"Th1 and Th2 cell differentiation";"Cardiolipin biosynthesis II";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Type I lipoteichoic acid biosynthesis (S. aureus)" JAMg_model_6318.2 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" JAMg_model_14197.1 12 Reactome: R-HSA-68962;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-174430;Reactome: R-HSA-194840;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-68952;Reactome: R-HSA-5696400 "Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Telomere C-strand synthesis initiation";"Rho GTPase cycle";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"DNA replication initiation";"Dual Incision in GG-NER" JAMg_model_4485.4 4 Reactome: R-HSA-5689603;MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847 "UCH proteinases";"Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis";"HATs acetylate histones" JAMg_model_3526.1 1 Reactome: R-HSA-9018519 "Estrogen-dependent gene expression" JAMg_model_9186.7 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism" JAMg_model_12983.2 3 Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3 "Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism" JAMg_model_10498.1 9 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-446343;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-446353;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Localization of the PINCH-ILK-PARVIN complex to focal adhesions";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Cell-extracellular matrix interactions";"Human immunodeficiency virus 1 infection" JAMg_model_16144.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_14520.2 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" JAMg_model_9216.1 12 MetaCyc: PWY-5855;MetaCyc: PWY-5873;MetaCyc: PWY-7230;MetaCyc: PWY-6708;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5871;MetaCyc: PWY-5872;Reactome: R-HSA-2142789;MetaCyc: PWY-5870;MetaCyc: PWY-5857;MetaCyc: PWY-5856;MetaCyc: PWY-7233 "Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)" JAMg_model_9427.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" JAMg_model_20378.1 5 Reactome: R-HSA-381038;Reactome: R-HSA-901032;Reactome: R-HSA-5358346;MetaCyc: PWY-7511;Reactome: R-HSA-5362768 "XBP1(S) activates chaperone genes";"ER Quality Control Compartment (ERQC)";"Hedgehog ligand biogenesis";"Protein ubiquitination";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" JAMg_model_8699.2 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" JAMg_model_7364.2 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8951664 "Neutrophil degranulation";"Neddylation" JAMg_model_1334.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" JAMg_model_3980.1 11 Reactome: R-HSA-111463;Reactome: R-HSA-611105;Reactome: R-HSA-9627069;Reactome: R-HSA-5628897;Reactome: R-HSA-2151201;Reactome: R-HSA-111457;Reactome: R-HSA-111459;Reactome: R-HSA-1268020;Reactome: R-HSA-3299685;Reactome: R-HSA-111464;Reactome: R-HSA-111458 "SMAC (DIABLO) binds to IAPs";"Respiratory electron transport";"Regulation of the apoptosome activity";"TP53 Regulates Metabolic Genes";"Transcriptional activation of mitochondrial biogenesis";"Release of apoptotic factors from the mitochondria";"Activation of caspases through apoptosome-mediated cleavage";"Mitochondrial protein import";"Detoxification of Reactive Oxygen Species";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome" JAMg_model_8676.1 2 Reactome: R-HSA-70895;KEGG: 00280+1.3.8.4 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" JAMg_model_12108.1 3 Reactome: R-HSA-111471;Reactome: R-HSA-140837;Reactome: R-HSA-9645722 "Apoptotic factor-mediated response";"Intrinsic Pathway of Fibrin Clot Formation";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function" JAMg_model_14354.1 9 Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-5674135;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-6798695;Reactome: R-HSA-380972 "TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"MAP2K and MAPK activation";"mTOR signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Neutrophil degranulation";"Energy dependent regulation of mTOR by LKB1-AMPK" JAMg_model_4874.6 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" JAMg_model_14870.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" JAMg_model_19128.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" JAMg_model_12792.1 7 Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-6798695 "Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Neutrophil degranulation" JAMg_model_2017.4 5 Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264;MetaCyc: PWY-5381;Reactome: R-HSA-1368108 "Neutrophil degranulation";"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" JAMg_model_409.3 14 Reactome: R-HSA-5687128;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-168333;Reactome: R-HSA-68877;Reactome: R-HSA-450520;Reactome: R-HSA-69273;Reactome: R-HSA-9634638;Reactome: R-HSA-2467813;Reactome: R-HSA-3769402;Reactome: R-HSA-2500257;Reactome: R-HSA-165054;Reactome: R-HSA-2173788;Reactome: R-HSA-9648025 "MAPK6/MAPK4 signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Mitotic Prometaphase";"HuR (ELAVL1) binds and stabilizes mRNA";"Cyclin A/B1/B2 associated events during G2/M transition";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Separation of Sister Chromatids";"Deactivation of the beta-catenin transactivating complex";"Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA";"Downregulation of TGF-beta receptor signaling";"EML4 and NUDC in mitotic spindle formation" JAMg_model_326.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_7407.3 1 Reactome: R-HSA-8963901 "Chylomicron remodeling" JAMg_model_1523.8 2 Reactome: R-HSA-8949613;Reactome: R-HSA-1268020 "Cristae formation";"Mitochondrial protein import" JAMg_model_10822.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" JAMg_model_8167.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" JAMg_model_4779.1 1 Reactome: R-HSA-201451 "Signaling by BMP" JAMg_model_21047.3 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" JAMg_model_17216.1 4 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-1268020;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial protein import";"Mitochondrial translation termination" JAMg_model_20628.2 1 Reactome: R-HSA-912446 "Meiotic recombination" JAMg_model_11773.3 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" JAMg_model_4185.6 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" JAMg_model_17785.10 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" JAMg_model_8363.2 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" JAMg_model_17847.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_17209.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" JAMg_model_1758.3 6 Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390471 "Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis" JAMg_model_21258.1 8 MetaCyc: PWY-7980;Reactome: R-HSA-1222556;KEGG: 00190+7.1.2.2;Reactome: R-HSA-983712;KEGG: 00195+7.1.2.2;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "ATP biosynthesis";"ROS and RNS production in phagocytes";"Oxidative phosphorylation";"Ion channel transport";"Photosynthesis";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling" JAMg_model_6844.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_4042.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_7528.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" JAMg_model_20344.1 8 MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;Reactome: R-HSA-5083633 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1" JAMg_model_943.2 1 Reactome: R-HSA-376172 "DSCAM interactions" JAMg_model_3438.1 3 Reactome: R-HSA-1566948;Reactome: R-HSA-1474228;Reactome: R-HSA-2129379 "Elastic fibre formation";"Degradation of the extracellular matrix";"Molecules associated with elastic fibres" JAMg_model_16966.2 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" JAMg_model_13351.1 5 Reactome: R-HSA-4085001;Reactome: R-HSA-4341670;Reactome: R-HSA-1660662;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695 "Sialic acid metabolism";"Defective NEU1 causes sialidosis";"Glycosphingolipid metabolism";"MHC class II antigen presentation";"Neutrophil degranulation" JAMg_model_9488.3 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" JAMg_model_859.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" JAMg_model_19638.2 13 Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689 "Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" JAMg_model_4352.1 15 Reactome: R-HSA-9603505;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167246 "NTRK3 as a dependence receptor";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript" JAMg_model_11140.3 16 Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-983168;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-176409 "APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of mitotic proteins" JAMg_model_409.2 14 Reactome: R-HSA-9634638;Reactome: R-HSA-2467813;Reactome: R-HSA-3769402;Reactome: R-HSA-69273;Reactome: R-HSA-450520;Reactome: R-HSA-2500257;Reactome: R-HSA-165054;Reactome: R-HSA-9648025;Reactome: R-HSA-2173788;Reactome: R-HSA-5687128;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-168333;Reactome: R-HSA-68877 "Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Separation of Sister Chromatids";"Deactivation of the beta-catenin transactivating complex";"Cyclin A/B1/B2 associated events during G2/M transition";"HuR (ELAVL1) binds and stabilizes mRNA";"Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA";"EML4 and NUDC in mitotic spindle formation";"Downregulation of TGF-beta receptor signaling";"MAPK6/MAPK4 signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Mitotic Prometaphase" JAMg_model_16586.1 3 Reactome: R-HSA-6783984;KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "Glycine degradation";"One carbon pool by folate";"Glycine, serine and threonine metabolism" JAMg_model_305.1 1 Reactome: R-HSA-1614558 "Degradation of cysteine and homocysteine" JAMg_model_17536.3 3 Reactome: R-HSA-3214847;MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "HATs acetylate histones";"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" JAMg_model_4834.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" JAMg_model_19485.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" JAMg_model_4349.4 8 Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-165054;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-68877 "Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Rev-mediated nuclear export of HIV RNA";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase" JAMg_model_6525.4 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" JAMg_model_357.1 9 Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167161 "RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation" JAMg_model_16999.1 8 Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-3371571;Reactome: R-HSA-380972;Reactome: R-HSA-166208 "TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Macroautophagy";"mTOR signalling";"HSF1-dependent transactivation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling" JAMg_model_15312.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" JAMg_model_10663.2 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" JAMg_model_15653.1 17 MetaCyc: PWY-1622;KEGG: 00710+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-7383;MetaCyc: PWY-561;KEGG: 00020+1.1.1.37;KEGG: 00720+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-5913;KEGG: 00620+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-5392;MetaCyc: PWY-8086;KEGG: 00630+1.1.1.37;MetaCyc: PWY-7115 "Formaldehyde assimilation I (serine pathway)";"Carbon fixation in photosynthetic organisms";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Cysteine and methionine metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Pyruvate metabolism";"Methane metabolism";"Methylaspartate cycle";"Reductive TCA cycle II";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Glyoxylate and dicarboxylate metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" JAMg_model_3346.1 4 MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32;KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051 "Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I" JAMg_model_12049.1 52 Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-5250924;Reactome: R-HSA-72203;Reactome: R-HSA-76042;Reactome: R-HSA-5601884;Reactome: R-HSA-6803529;Reactome: R-HSA-1834949;Reactome: R-HSA-9018519;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-76061;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-75953;Reactome: R-HSA-76071;Reactome: R-HSA-167200;Reactome: R-HSA-76066;Reactome: R-HSA-6796648;Reactome: R-HSA-73762;Reactome: R-HSA-73980;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-6782135;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-6781823;Reactome: R-HSA-73863;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-5617472;Reactome: R-HSA-167172;Reactome: R-HSA-8851708;Reactome: R-HSA-77075;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-203927;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-72163;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-167160;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-168325;Reactome: R-HSA-6781827;Reactome: R-HSA-6807505 "Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"B-WICH complex positively regulates rRNA expression";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"PIWI-interacting RNA (piRNA) biogenesis";"FGFR2 alternative splicing";"Cytosolic sensors of pathogen-associated DNA";"Estrogen-dependent gene expression";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"Dual incision in TC-NER";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Termination";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcription of the HIV genome";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"MicroRNA (miRNA) biogenesis";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"mRNA Splicing - Major Pathway";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Viral Messenger RNA Synthesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA polymerase II transcribes snRNA genes" JAMg_model_19491.1 4 MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7;Reactome: R-HSA-1362409;Reactome: R-HSA-947581 "[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism";"Mitochondrial iron-sulfur cluster biogenesis";"Molybdenum cofactor biosynthesis" JAMg_model_1632.2 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" JAMg_model_8031.2 3 MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+2.10.1.1 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" JAMg_model_8134.2 4 MetaCyc: PWY-5188;Reactome: R-HSA-189451;KEGG: 00860+4.2.1.75;MetaCyc: PWY-5189 "Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)" JAMg_model_860.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" JAMg_model_2842.1 17 Reactome: R-HSA-983168;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-9633012 "Antigen processing: Ubiquitination & Proteasome degradation";"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency" JAMg_model_4701.2 4 Reactome: R-HSA-189483;MetaCyc: PWY-5874;KEGG: 00860+1.14.14.18;Reactome: R-HSA-917937 "Heme degradation";"Heme degradation I";"Porphyrin and chlorophyll metabolism";"Iron uptake and transport" JAMg_model_561.1 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_8199.1 8 KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"Activation of RAC1";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway" JAMg_model_1689.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_1640.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" JAMg_model_5574.3 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" JAMg_model_18681.2 1 KEGG: 00230+4.6.1.2 "Purine metabolism" JAMg_model_15509.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" JAMg_model_5139.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" JAMg_model_8640.1 7 Reactome: R-HSA-6804114;Reactome: R-HSA-1538133;Reactome: R-HSA-2173796;Reactome: R-HSA-1362300;Reactome: R-HSA-69231;Reactome: R-HSA-69205;Reactome: R-HSA-1362277 "TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G0 and Early G1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin D associated events in G1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex" JAMg_model_18024.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" JAMg_model_11422.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_10981.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" JAMg_model_10344.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" JAMg_model_6758.3 7 KEGG: 00020+2.3.1.61;Reactome: R-HSA-71064;Reactome: R-HSA-389661;KEGG: 00380+2.3.1.61;KEGG: 00310+2.3.1.61;Reactome: R-HSA-71403;MetaCyc: PWY-5084 "Citrate cycle (TCA cycle)";"Lysine catabolism";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Lysine degradation";"Citric acid cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA" JAMg_model_2260.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" JAMg_model_1823.1 13 MetaCyc: PWY-7410;MetaCyc: PWY-6383;MetaCyc: PWY-7736;MetaCyc: PWY-7659;MetaCyc: PWY-5123;MetaCyc: PWY-7141;MetaCyc: PWY-7102;MetaCyc: PWY-5122;MetaCyc: PWY-6859;MetaCyc: PWY-7721;MetaCyc: PWY-7709;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7182 "Ipsdienol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Stellatic acid biosynthesis";"Viridicatumtoxin biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"(3S)-linalool biosynthesis";"Bisabolene biosynthesis (engineered)";"Geranyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"Methyl phomopsenoate biosynthesis";"(3R)-linalool biosynthesis";"Terpenoid backbone biosynthesis";"Linalool biosynthesis I" JAMg_model_393.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_65.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259 "Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism" JAMg_model_7655.3 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" JAMg_model_4813.2 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" JAMg_model_20738.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_15725.4 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" JAMg_model_14229.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_16579.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_18125.4 9 MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52 "Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism" JAMg_model_21066.2 15 Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-167246;Reactome: R-HSA-2173796;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-176034;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167287 "RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"Tat-mediated elongation of the HIV-1 transcript";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Interactions of Tat with host cellular proteins";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery" JAMg_model_3454.3 3 MetaCyc: PWY-6619;Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20 "Adenine and adenosine salvage VI";"Purine salvage";"Purine metabolism" JAMg_model_7284.1 43 Reactome: R-HSA-5358749;Reactome: R-HSA-198753;Reactome: R-HSA-163767;Reactome: R-HSA-113501;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-6804757;Reactome: R-HSA-380259;Reactome: R-HSA-2465910;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-6811558;Reactome: R-HSA-1295596;Reactome: R-HSA-9634600;Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-5673000;Reactome: R-HSA-69231;Reactome: R-HSA-975957;Reactome: R-HSA-5467337;Reactome: R-HSA-5675221;Reactome: R-HSA-5467348;Reactome: R-HSA-180024;Reactome: R-HSA-380284;Reactome: R-HSA-68877;Reactome: R-HSA-5358752;Reactome: R-HSA-4641262;Reactome: R-HSA-69273;Reactome: R-HSA-5358747;Reactome: R-HSA-2995383;Reactome: R-HSA-202670;Reactome: R-HSA-380320;Reactome: R-HSA-141444;Reactome: R-HSA-2565942;Reactome: R-HSA-5663220;Reactome: R-HSA-195253;Reactome: R-HSA-432142;Reactome: R-HSA-380270;Reactome: R-HSA-5467340;Reactome: R-HSA-8854518;Reactome: R-HSA-196299;Reactome: R-HSA-5620912;Reactome: R-HSA-163685 "S37 mutants of beta-catenin aren't phosphorylated";"ERK/MAPK targets";"PP2A-mediated dephosphorylation of key metabolic factors";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Regulation of TP53 Degradation";"Loss of Nlp from mitotic centrosomes";"MASTL Facilitates Mitotic Progression";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Spry regulation of FGF signaling";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"RAF activation";"Cyclin D associated events in G1";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"APC truncation mutants have impaired AXIN binding";"Negative regulation of MAPK pathway";"Truncations of AMER1 destabilize the destruction complex";"DARPP-32 events";"Loss of proteins required for interphase microtubule organization from the centrosome";"Mitotic Prometaphase";"T41 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Cyclin A/B1/B2 associated events during G2/M transition";"S33 mutants of beta-catenin aren't phosphorylated";"Initiation of Nuclear Envelope Reformation";"ERKs are inactivated";"Recruitment of NuMA to mitotic centrosomes";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of PLK1 Activity at G2/M Transition";"RHO GTPases Activate Formins";"Degradation of beta-catenin by the destruction complex";"Platelet sensitization by LDL";"Recruitment of mitotic centrosome proteins and complexes";"AXIN missense mutants destabilize the destruction complex";"AURKA Activation by TPX2";"Beta-catenin phosphorylation cascade";"Anchoring of the basal body to the plasma membrane";"Integration of energy metabolism" JAMg_model_10856.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" JAMg_model_8900.3 2 Reactome: R-HSA-1268020;Reactome: R-HSA-71403 "Mitochondrial protein import";"Citric acid cycle (TCA cycle)" JAMg_model_583.5 1 Reactome: R-HSA-71384 "Ethanol oxidation" JAMg_model_5088.1 16 MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-1042;MetaCyc: PWY-7124;MetaCyc: PWY-7218;KEGG: 00010+4.2.1.11;MetaCyc: PWY-6142;MetaCyc: PWY-8004;MetaCyc: PWY-6886;MetaCyc: PWY-1622;MetaCyc: PWY-5723;Reactome: R-HSA-70263;MetaCyc: PWY-5484;KEGG: 00680+4.2.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-7003 "Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Ethylene biosynthesis V (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Formaldehyde assimilation I (serine pathway)";"Rubisco shunt";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycolysis";"Glycerol degradation to butanol" JAMg_model_113.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_5682.2 1 Reactome: R-HSA-3295583 "TRP channels" JAMg_model_4331.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" JAMg_model_7864.4 3 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis" JAMg_model_4970.3 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" JAMg_model_3632.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" JAMg_model_7461.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_20314.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_156.2 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_20586.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" JAMg_model_11239.2 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_10058.3 2 Reactome: R-HSA-6785470;Reactome: R-HSA-6784531 "tRNA processing in the mitochondrion";"tRNA processing in the nucleus" JAMg_model_14120.1 11 Reactome: R-HSA-4420097;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-171007;Reactome: R-HSA-450302;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1 "VEGFA-VEGFR2 Pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Oxidative Stress Induced Senescence";"p38MAPK events";"activated TAK1 mediates p38 MAPK activation";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway" JAMg_model_17216.2 4 Reactome: R-HSA-5389840;Reactome: R-HSA-1268020;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial protein import";"Mitochondrial translation termination";"Mitochondrial translation initiation" JAMg_model_17419.3 12 Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-381038;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-8854518 "Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"XBP1(S) activates chaperone genes";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"AURKA Activation by TPX2" JAMg_model_3148.2 8 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Signaling by Hippo";"Human cytomegalovirus infection" JAMg_model_16448.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" JAMg_model_9194.2 6 MetaCyc: PWY-7234;Reactome: R-HSA-73817;KEGG: 00230+3.5.4.10+2.1.2.3;KEGG: 00670+2.1.2.3;MetaCyc: PWY-6124;MetaCyc: PWY-6123 "Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I" JAMg_model_5088.4 16 Reactome: R-HSA-70171;MetaCyc: PWY-7003;KEGG: 00680+4.2.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-8004;MetaCyc: PWY-6886;MetaCyc: PWY-1622;MetaCyc: PWY-5723;Reactome: R-HSA-70263;KEGG: 00010+4.2.1.11;MetaCyc: PWY-6142;MetaCyc: PWY-6901;MetaCyc: PWY-1042;MetaCyc: PWY-7124;MetaCyc: PWY-7218;MetaCyc: PWY-2221 "Glycolysis";"Glycerol degradation to butanol";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Formaldehyde assimilation I (serine pathway)";"Rubisco shunt";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Ethylene biosynthesis V (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)" JAMg_model_21301.1 3 Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import" JAMg_model_12780.3 2 Reactome: R-HSA-3214815;Reactome: R-HSA-427413 "HDACs deacetylate histones";"NoRC negatively regulates rRNA expression" JAMg_model_9518.2 1 Reactome: R-HSA-5620924 "Intraflagellar transport" JAMg_model_2206.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" JAMg_model_15950.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" JAMg_model_11757.4 6 Reactome: R-HSA-8874211;Reactome: R-HSA-8957275;Reactome: R-HSA-8963889;Reactome: R-HSA-1655829;Reactome: R-HSA-381033;Reactome: R-HSA-381426 "CREB3 factors activate genes";"Post-translational protein phosphorylation";"Assembly of active LPL and LIPC lipase complexes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" JAMg_model_19213.3 3 KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807;Reactome: R-HSA-6798695 "Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation" JAMg_model_4487.2 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" JAMg_model_9280.3 4 Reactome: R-HSA-3232142;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-1234176 "SUMOylation of ubiquitinylation proteins";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha" JAMg_model_19898.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" JAMg_model_3199.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" JAMg_model_19107.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" JAMg_model_13230.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" JAMg_model_6375.2 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_17676.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" JAMg_model_4235.1 6 MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23 "Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Galactose metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism" JAMg_model_19167.1 11 KEGG: 00565+3.1.3.4;MetaCyc: PWY-8051;Reactome: R-HSA-2029485;KEGG: 00561+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-8053;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052;KEGG: 00564+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8055 "Ether lipid metabolism";"Anandamide biosynthesis I";"Role of phospholipids in phagocytosis";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis" JAMg_model_10409.2 3 Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network" JAMg_model_14338.3 5 Reactome: R-HSA-2206305;Reactome: R-HSA-2022857;Reactome: R-HSA-432720;Reactome: R-HSA-6798695;KEGG: 00531+3.1.6.14 "MPS IIID - Sanfilippo syndrome D";"Keratan sulfate degradation";"Lysosome Vesicle Biogenesis";"Neutrophil degranulation";"Glycosaminoglycan degradation" JAMg_model_5534.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" JAMg_model_13503.2 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" JAMg_model_2200.1 3 Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis" JAMg_model_8220.4 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_18051.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-5689880 "Translesion Synthesis by POLH";"Ub-specific processing proteases" JAMg_model_671.2 6 Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5685938 "Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)" JAMg_model_8784.3 3 Reactome: R-HSA-5693571;Reactome: R-HSA-3108214;Reactome: R-HSA-164843 "Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins";"2-LTR circle formation" JAMg_model_9696.1 27 Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-168276 "SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways" JAMg_model_17808.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" JAMg_model_10407.2 3 Reactome: R-HSA-6811440;Reactome: R-HSA-8876198;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic" JAMg_model_20739.1 1 Reactome: R-HSA-8949613 "Cristae formation" JAMg_model_13503.5 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" JAMg_model_13054.5 3 KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" JAMg_model_18807.1 2 Reactome: R-HSA-210746;Reactome: R-HSA-210745 "Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells";"Regulation of gene expression in beta cells" JAMg_model_10566.3 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" JAMg_model_19067.1 9 MetaCyc: PWY-7115;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;Reactome: R-HSA-1475029;MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-241 "C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type" JAMg_model_13295.2 5 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-176407;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5687128 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Th1 and Th2 cell differentiation";"MAPK6/MAPK4 signaling" JAMg_model_19983.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_1264.1 3 Reactome: R-HSA-1660517;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514 "Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane" JAMg_model_4582.1 7 MetaCyc: PWY-8026;Reactome: R-HSA-9022692;MetaCyc: PWY-7154;MetaCyc: PWY-2541;Reactome: R-HSA-191273;MetaCyc: PWY-6074;KEGG: 00100+1.3.1.70 "Sterol biosynthesis (methylotrophs)";"Regulation of MECP2 expression and activity";"Ergosterol biosynthesis II";"Phytosterol biosynthesis (plants)";"Cholesterol biosynthesis";"Zymosterol biosynthesis";"Steroid biosynthesis" JAMg_model_6360.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" JAMg_model_7191.1 4 Reactome: R-HSA-5683678;Reactome: R-HSA-5683826;Reactome: R-HSA-5688399;Reactome: R-HSA-1369062 "Defective ABCA3 causes pulmonary surfactant metabolism dysfunction type 3 (SMDP3)";"Surfactant metabolism";"Defective ABCA3 causes pulmonary surfactant metabolism dysfunction 3 (SMDP3)";"ABC transporters in lipid homeostasis" JAMg_model_8298.5 4 Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" JAMg_model_3193.1 4 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis" JAMg_model_15870.7 8 KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171 "Galactose metabolism";"Glycolysis / Gluconeogenesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Starch and sucrose metabolism";"Streptomycin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycolysis" JAMg_model_12569.1 13 MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5537;Reactome: R-HSA-71403;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5913;MetaCyc: PWY-6969;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5 "Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Propanoate metabolism" JAMg_model_583.7 1 Reactome: R-HSA-71384 "Ethanol oxidation" JAMg_model_18110.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-5972 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)" JAMg_model_19605.1 3 MetaCyc: PWY-7887;Reactome: R-HSA-6787450;MetaCyc: PWY-7892 "Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)" JAMg_model_13332.1 5 MetaCyc: PWY-7383;KEGG: 00010+4.1.1.32;KEGG: 00620+4.1.1.32;Reactome: R-HSA-70263;KEGG: 00020+4.1.1.32 "Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Gluconeogenesis";"Citrate cycle (TCA cycle)" JAMg_model_7957.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_10182.2 5 Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-983231;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295 "COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Factors involved in megakaryocyte development and platelet production";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" JAMg_model_19003.5 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_13514.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" JAMg_model_11556.5 15 Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723 "Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation" JAMg_model_15388.1 4 Reactome: R-HSA-8939243;Reactome: R-HSA-375280;Reactome: R-HSA-416476;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Amine ligand-binding receptors";"G alpha (q) signalling events";"RMTs methylate histone arginines" JAMg_model_5767.1 1 Reactome: R-HSA-191859 "snRNP Assembly" JAMg_model_583.3 1 Reactome: R-HSA-71384 "Ethanol oxidation" JAMg_model_16456.3 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" JAMg_model_11719.1 7 KEGG: 00270+6.3.2.2;MetaCyc: PWY-7255;KEGG: 00480+6.3.2.2;MetaCyc: PWY-8043;Reactome: R-HSA-5578999;MetaCyc: PWY-6840;Reactome: R-HSA-174403 "Cysteine and methionine metabolism";"Ergothioneine biosynthesis I (bacteria)";"Glutathione metabolism";"Ophthalmate biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Homoglutathione biosynthesis";"Glutathione synthesis and recycling" JAMg_model_11511.2 7 KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2;Reactome: R-HSA-5628897;Reactome: R-HSA-210500;MetaCyc: PWY-5921 "Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"TP53 Regulates Metabolic Genes";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation" JAMg_model_1555.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_13830.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" JAMg_model_7234.1 5 Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-3214815 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones" JAMg_model_1679.1 22 Reactome: R-HSA-196299;Reactome: R-HSA-5673000;Reactome: R-HSA-389513;Reactome: R-HSA-5467340;Reactome: R-HSA-5339716;Reactome: R-HSA-432142;Reactome: R-HSA-195253;Reactome: R-HSA-6811558;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747;Reactome: R-HSA-2467813;Reactome: R-HSA-4641262;Reactome: R-HSA-5358752;Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-5675221;Reactome: R-HSA-5358749;Reactome: R-HSA-5467337 "Beta-catenin phosphorylation cascade";"RAF activation";"CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Platelet sensitization by LDL";"Degradation of beta-catenin by the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"T41 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"Negative regulation of MAPK pathway";"S37 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding" JAMg_model_18035.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_12739.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_10072.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" JAMg_model_20988.2 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" JAMg_model_2486.2 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" JAMg_model_6301.1 3 Reactome: R-HSA-2022854;Reactome: R-HSA-5173105;Reactome: R-HSA-5083627 "Keratan sulfate biosynthesis";"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6" JAMg_model_9084.3 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" JAMg_model_1520.2 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" JAMg_model_17411.1 4 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events" JAMg_model_4987.1 29 Reactome: R-HSA-5696397;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-68962;Reactome: R-HSA-174437;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-69166;Reactome: R-HSA-176187;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-3371453;Reactome: R-HSA-5696395;Reactome: R-HSA-5685938;Reactome: R-HSA-3108214;Reactome: R-HSA-3371511;Reactome: R-HSA-912446;Reactome: R-HSA-6782135;Reactome: R-HSA-6783310;Reactome: R-HSA-5655862;Reactome: R-HSA-5696400;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-6804756 "Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate from the C-strand";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"Regulation of HSF1-mediated heat shock response";"Formation of Incision Complex in GG-NER";"HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins";"HSF1 activation";"Meiotic recombination";"Dual incision in TC-NER";"Fanconi Anemia Pathway";"Translesion synthesis by POLK";"Dual Incision in GG-NER";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of TP53 Activity through Phosphorylation" JAMg_model_107.2 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" JAMg_model_7694.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" JAMg_model_16038.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" JAMg_model_20545.1 4 Reactome: R-HSA-6807062;MetaCyc: PWY-8026;Reactome: R-HSA-6807047;KEGG: 00100+1.3.1.72 "Cholesterol biosynthesis via lathosterol";"Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via desmosterol";"Steroid biosynthesis" JAMg_model_8435.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_8235.1 12 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-6804756;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167287 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery" JAMg_model_598.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" JAMg_model_15268.3 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_3521.1 8 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis" JAMg_model_9952.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" JAMg_model_19272.1 2 KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921 "Histidine metabolism";"Histidine catabolism" JAMg_model_21105.2 4 Reactome: R-HSA-936440;Reactome: R-HSA-5205685;Reactome: R-HSA-1632852;Reactome: R-HSA-8934903 "Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy";"Macroautophagy";"Receptor Mediated Mitophagy" JAMg_model_3454.4 3 Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619 "Purine salvage";"Purine metabolism";"Adenine and adenosine salvage VI" JAMg_model_7849.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_13316.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_18903.1 13 Reactome: R-HSA-71403;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-6728;MetaCyc: PWY-7384;MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5538 "Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate VI" JAMg_model_8941.1 7 Reactome: R-HSA-380994;Reactome: R-HSA-426117;Reactome: R-HSA-8963693;Reactome: R-HSA-5619039;Reactome: R-HSA-9633012;Reactome: R-HSA-9648895;KEGG: 00250+6.3.5.4 "ATF4 activates genes in response to endoplasmic reticulum stress";"Cation-coupled Chloride cotransporters";"Aspartate and asparagine metabolism";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Response of EIF2AK1 (HRI) to heme deficiency";"Alanine, aspartate and glutamate metabolism" JAMg_model_5764.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" JAMg_model_12676.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" JAMg_model_1504.1 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" JAMg_model_8783.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" JAMg_model_11369.1 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_16020.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" JAMg_model_7092.1 5 Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2 "Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism" JAMg_model_4892.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" JAMg_model_11451.1 8 KEGG: 00270+1.1.1.27;MetaCyc: PWY-6901;KEGG: 00640+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00010+1.1.1.27;KEGG: 00620+1.1.1.27;MetaCyc: PWY-8086;MetaCyc: PWY-5481 "Cysteine and methionine metabolism";"Superpathway of glucose and xylose degradation";"Propanoate metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate fermentation to (S)-lactate" JAMg_model_15065.1 1 Reactome: R-HSA-1632852 "Macroautophagy" JAMg_model_3871.1 6 Reactome: R-HSA-1855183;MetaCyc: PWY-6362;MetaCyc: PWY-6364;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.56 "Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism" JAMg_model_8463.1 26 Reactome: R-HSA-4615885;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-110314;Reactome: R-HSA-174414;Reactome: R-HSA-174411;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-110312;Reactome: R-HSA-8866654;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-5655862;Reactome: R-HSA-174437;Reactome: R-HSA-5358606;Reactome: R-HSA-69183;Reactome: R-HSA-5358565;Reactome: R-HSA-5696397;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-174417;Reactome: R-HSA-6782210;Reactome: R-HSA-69166;Reactome: R-HSA-6804114 "SUMOylation of DNA replication proteins";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"Recognition of DNA damage by PCNA-containing replication complex";"Processive synthesis on the C-strand of the telomere";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Translesion synthesis by REV1";"E3 ubiquitin ligases ubiquitinate target proteins";"Dual incision in TC-NER";"Polymerase switching";"Translesion synthesis by POLK";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processive synthesis on the lagging strand";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Telomere C-strand (Lagging Strand) Synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest" JAMg_model_9454.3 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" JAMg_model_20489.2 11 Reactome: R-HSA-140534;Reactome: R-HSA-75157;Reactome: R-HSA-933543;Reactome: R-HSA-69416;Reactome: R-HSA-5213460;Reactome: R-HSA-75158;Reactome: R-HSA-2562578;Reactome: R-HSA-5357786;Reactome: R-HSA-3371378;Reactome: R-HSA-5218900;Reactome: R-HSA-9013957 "Caspase activation via Death Receptors in the presence of ligand";"FasL/ CD95L signaling";"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10";"Dimerization of procaspase-8";"RIPK1-mediated regulated necrosis";"TRAIL signaling";"TRIF-mediated programmed cell death";"TNFR1-induced proapoptotic signaling";"Regulation by c-FLIP";"CASP8 activity is inhibited";"TLR3-mediated TICAM1-dependent programmed cell death" JAMg_model_7189.6 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" JAMg_model_12121.2 6 Reactome: R-HSA-1483166;Reactome: R-HSA-163560;MetaCyc: PWY-4261;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6952;MetaCyc: PWY-6118 "Synthesis of PA";"Triglyceride catabolism";"Glycerol degradation I";"Glycerophospholipid metabolism";"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle" JAMg_model_8378.1 5 Reactome: R-HSA-6804756;Reactome: R-HSA-5668599;Reactome: R-HSA-6811555;Reactome: R-HSA-936440;Reactome: R-HSA-1169408 "Regulation of TP53 Activity through Phosphorylation";"RHO GTPases Activate NADPH Oxidases";"PI5P Regulates TP53 Acetylation";"Negative regulators of DDX58/IFIH1 signaling";"ISG15 antiviral mechanism" JAMg_model_12880.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" JAMg_model_6140.1 40 KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;MetaCyc: PWY-6944;KEGG: 00903+4.2.1.17;KEGG: 00592+4.2.1.17;MetaCyc: PWY-7401;MetaCyc: PWY-7726;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;MetaCyc: PWY-7656;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-6583;MetaCyc: PWY-5177;MetaCyc: PWY-5138;KEGG: 00410+4.2.1.17;KEGG: 00627+4.2.1.17;KEGG: 00360+4.2.1.17;KEGG: 00623+1.1.1.35;MetaCyc: PWY-1361;MetaCyc: PWY-7216;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;MetaCyc: PWY-7606;KEGG: 00640+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;MetaCyc: PWY-6946;MetaCyc: PWY-7094;MetaCyc: PWY-7778;MetaCyc: PWY-6945;MetaCyc: PWY-6435;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;MetaCyc: PWY-5136;KEGG: 00062+4.2.1.17+1.1.1.35 "Benzoate degradation";"Tryptophan metabolism";"Methyl ketone biosynthesis (engineered)";"Androstenedione degradation";"Limonene and pinene degradation";"alpha-Linolenic acid metabolism";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid degradation";"Fermentation to 2-methylbutanoate";"Lysine degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Spodoptera littoralis pheromone biosynthesis";"Valine, leucine and isoleucine degradation";"Pyruvate fermentation to butanol II (engineered)";"Pyruvate fermentation to butanol I";"Glutaryl-coa degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"beta-Alanine metabolism";"Aminobenzoate degradation";"Phenylalanine metabolism";"Toluene degradation";"Benzoyl-coa degradation I (aerobic)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Carbon fixation pathways in prokaryotes";"Caprolactam degradation";"Methyl tert-butyl ether degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"Geraniol degradation";"Pyruvate fermentation to hexanol (engineered)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Fatty acid salvage";"2-methylpropene degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"4-hydroxybenzoate biosynthesis III (plants)";"Butanoate metabolism";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid elongation" JAMg_model_12354.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" JAMg_model_12693.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" JAMg_model_10021.7 4 KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841;KEGG: 00053+1.13.99.1;Reactome: R-HSA-1855183 "Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Ascorbate and aldarate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol" JAMg_model_3303.3 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" JAMg_model_6331.1 14 Reactome: R-HSA-2467813;Reactome: R-HSA-1632852;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-5620924;Reactome: R-HSA-68877;Reactome: R-HSA-9609690 "Separation of Sister Chromatids";"Macroautophagy";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Intraflagellar transport";"Mitotic Prometaphase";"HCMV Early Events" JAMg_model_7050.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" JAMg_model_10887.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" JAMg_model_1571.1 3 Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-390471 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Association of TriC/CCT with target proteins during biosynthesis" JAMg_model_2102.2 16 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-975956 "Viral mRNA Translation";"Peptide chain elongation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" JAMg_model_19637.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" JAMg_model_3080.3 7 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection" JAMg_model_4986.1 29 Reactome: R-HSA-68962;Reactome: R-HSA-174437;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-5696397;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-6782210;Reactome: R-HSA-69166;Reactome: R-HSA-176187;Reactome: R-HSA-912446;Reactome: R-HSA-3108214;Reactome: R-HSA-3371511;Reactome: R-HSA-5685938;Reactome: R-HSA-5696395;Reactome: R-HSA-3371453;Reactome: R-HSA-110314;Reactome: R-HSA-6804756;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-6783310 "Activation of the pre-replicative complex";"Removal of the Flap Intermediate from the C-strand";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate";"Activation of ATR in response to replication stress";"Meiotic recombination";"SUMOylation of DNA damage response and repair proteins";"HSF1 activation";"HDR through Single Strand Annealing (SSA)";"Formation of Incision Complex in GG-NER";"Regulation of HSF1-mediated heat shock response";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of TP53 Activity through Phosphorylation";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Translesion synthesis by REV1";"Dual incision in TC-NER";"Translesion synthesis by POLK";"Fanconi Anemia Pathway" JAMg_model_10537.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" JAMg_model_11489.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_17907.2 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" JAMg_model_16703.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" JAMg_model_13717.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_9243.3 1 Reactome: R-HSA-6785631 "ERBB2 Regulates Cell Motility" JAMg_model_1964.2 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" JAMg_model_7381.2 7 KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-6824 "Phenylpropanoid biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis" JAMg_model_13540.2 1 Reactome: R-HSA-71384 "Ethanol oxidation" JAMg_model_10881.2 4 Reactome: R-HSA-8934903;Reactome: R-HSA-1632852;Reactome: R-HSA-936440;Reactome: R-HSA-5205685 "Receptor Mediated Mitophagy";"Macroautophagy";"Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy" JAMg_model_12290.1 18 KEGG: 00240+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7220;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7226;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7197;MetaCyc: PWY-7184;MetaCyc: PWY-7205;MetaCyc: PWY-6545;Reactome: R-HSA-499943;MetaCyc: PWY-7187;MetaCyc: PWY-7221;MetaCyc: PWY-7227;MetaCyc: PWY-7176;MetaCyc: PWY-7222;MetaCyc: PWY-7224 "Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage" JAMg_model_18499.2 2 KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" JAMg_model_13401.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-606279;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Deposition of new CENPA-containing nucleosomes at the centromere";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase" JAMg_model_20384.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" JAMg_model_17042.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" JAMg_model_4261.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" JAMg_model_17943.3 5 Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-5625740 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs" JAMg_model_13890.1 2 MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4 "Cellulose degradation II (fungi)";"Starch and sucrose metabolism" JAMg_model_3083.1 3 Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-5689880 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Ub-specific processing proteases" JAMg_model_16071.4 9 Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-114608;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-445355;Reactome: R-HSA-6802948 "MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Platelet degranulation";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants" JAMg_model_9900.3 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" JAMg_model_11978.4 2 MetaCyc: PWY-7511;Reactome: R-HSA-5689880 "Protein ubiquitination";"Ub-specific processing proteases" JAMg_model_12510.1 1 Reactome: R-HSA-6803207 "TP53 Regulates Transcription of Caspase Activators and Caspases" JAMg_model_1124.3 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" JAMg_model_3944.2 2 Reactome: R-HSA-5576886;Reactome: R-HSA-1299308 "Phase 4 - resting membrane potential";"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)" JAMg_model_17563.2 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" JAMg_model_13483.2 16 Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Peptide chain elongation" JAMg_model_13183.2 14 Reactome: R-HSA-2022857;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-194840;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52 "Keratan sulfate degradation";"CS/DS degradation";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"Rho GTPase cycle";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series" JAMg_model_10149.3 3 Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646 "Defective ACY1 causes encephalopathy";"Arginine biosynthesis";"Aflatoxin activation and detoxification" JAMg_model_3430.5 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" JAMg_model_2499.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" JAMg_model_13587.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_3525.3 5 Reactome: R-HSA-901042;Reactome: R-HSA-879415;Reactome: R-HSA-532668;Reactome: R-HSA-381426;Reactome: R-HSA-8957275 "Calnexin/calreticulin cycle";"Advanced glycosylation endproduct receptor signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation" JAMg_model_5890.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" JAMg_model_9563.3 5 Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390471 "Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis" JAMg_model_6599.5 1 Reactome: R-HSA-189200 "Cellular hexose transport" JAMg_model_10853.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" JAMg_model_12508.7 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" JAMg_model_11895.5 5 MetaCyc: PWY-7766;Reactome: R-HSA-189451;KEGG: 00860+4.1.1.37;MetaCyc: PWY-5531;MetaCyc: PWY-7159 "Heme b biosynthesis IV (Gram-positive bacteria)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)" JAMg_model_9347.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_2481.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" JAMg_model_3063.1 1 Reactome: R-HSA-1632852 "Macroautophagy" JAMg_model_3086.2 14 Reactome: R-HSA-9013700;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-3928665;Reactome: R-HSA-9013507;Reactome: R-HSA-1474228;Reactome: R-HSA-2644606;Reactome: R-HSA-6798695;Reactome: R-HSA-9017802;Reactome: R-HSA-977225;Reactome: R-HSA-1251985;Reactome: R-HSA-205043;Reactome: R-HSA-193692 "NOTCH4 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Degradation of the extracellular matrix";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Neutrophil degranulation";"Noncanonical activation of NOTCH3";"Amyloid fiber formation";"Nuclear signaling by ERBB4";"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR" JAMg_model_13646.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_5561.3 5 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1" JAMg_model_6910.1 6 Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-434316 "ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion" JAMg_model_1734.1 5 Reactome: R-HSA-165159;Reactome: R-HSA-3371571;Reactome: R-HSA-198323;Reactome: R-HSA-166208;Reactome: R-HSA-5674400 "mTOR signalling";"HSF1-dependent transactivation";"AKT phosphorylates targets in the cytosol";"mTORC1-mediated signalling";"Constitutive Signaling by AKT1 E17K in Cancer" JAMg_model_8879.1 1 Reactome: R-HSA-1632852 "Macroautophagy" JAMg_model_11704.3 7 KEGG: 00250+2.4.2.14;MetaCyc: PWY-7282;Reactome: R-HSA-73817;MetaCyc: PWY-6122;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6277;MetaCyc: PWY-6121 "Alanine, aspartate and glutamate metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I" JAMg_model_19465.1 30 Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-917937;Reactome: R-HSA-8939902;Reactome: R-HSA-1170546;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-2122947;Reactome: R-HSA-2644607;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-5684264;Reactome: R-HSA-195253;Reactome: R-HSA-2565942;Reactome: R-HSA-69231;Reactome: R-HSA-2644606;Reactome: R-HSA-5607764;Reactome: R-HSA-2894862;Reactome: R-HSA-400253 "Interleukin-1 signaling";"Orc1 removal from chromatin";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Iron uptake and transport";"Regulation of RUNX2 expression and activity";"Prolactin receptor signaling";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"NOTCH1 Intracellular Domain Regulates Transcription";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Degradation of beta-catenin by the destruction complex";"Regulation of PLK1 Activity at G2/M Transition";"Cyclin D associated events in G1";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"CLEC7A (Dectin-1) signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Circadian Clock" JAMg_model_1687.4 16 Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-983168 "CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_8694.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" JAMg_model_2672.2 5 Reactome: R-HSA-3134975;Reactome: R-HSA-3249367;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-1834941 "Regulation of innate immune responses to cytosolic DNA";"STAT6-mediated induction of chemokines";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"STING mediated induction of host immune responses" JAMg_model_18561.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" JAMg_model_1730.1 3 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.4;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism" JAMg_model_148.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_8630.1 2 MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4 "Cellulose degradation II (fungi)";"Starch and sucrose metabolism" JAMg_model_6552.2 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" JAMg_model_15508.6 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" JAMg_model_1909.5 1 Reactome: R-HSA-8949664 "Processing of SMDT1" JAMg_model_17564.2 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942 "Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition" JAMg_model_15126.5 13 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72706 "Viral mRNA Translation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit" JAMg_model_3756.4 6 MetaCyc: PWY-5668;MetaCyc: PWY-5269;MetaCyc: PWY-7817;Reactome: R-HSA-1483166;Reactome: R-HSA-1483148;KEGG: 00564+2.7.8.5 "Cardiolipin biosynthesis I";"Cardiolipin biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Synthesis of PA";"Synthesis of PG";"Glycerophospholipid metabolism" JAMg_model_10493.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_8560.2 24 Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-983189 "MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Mitotic Prometaphase";"HCMV Early Events";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"Kinesins" JAMg_model_7500.3 19 MetaCyc: PWY-7007;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7726;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7288;MetaCyc: PWY-735;MetaCyc: PWY-7854;MetaCyc: PWY-7291;MetaCyc: PWY-5136;MetaCyc: PWY-7340;MetaCyc: PWY-6920;MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7337 "Methyl ketone biosynthesis (engineered)";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II";"alpha-Linolenic acid metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"10-cis-heptadecenoyl-CoA degradation (yeast)" JAMg_model_14518.2 1 Reactome: R-HSA-5620924 "Intraflagellar transport" JAMg_model_8885.3 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" JAMg_model_20398.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" JAMg_model_10401.3 3 Reactome: R-HSA-5689877;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395 "Josephin domain DUBs";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER" JAMg_model_9967.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" JAMg_model_8124.3 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" JAMg_model_11108.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" JAMg_model_14654.4 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_19213.1 3 Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51 "Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation" JAMg_model_450.1 1 Reactome: R-HSA-8964038 "LDL clearance" JAMg_model_11669.1 5 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-3295583;Reactome: R-HSA-418890;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"TRP channels";"Role of second messengers in netrin-1 signaling";"Nicotinate metabolism" JAMg_model_13624.2 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394 "Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER" JAMg_model_6411.2 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" JAMg_model_18568.1 2 Reactome: R-HSA-2206307;Reactome: R-HSA-2024096 "MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation" JAMg_model_480.5 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" JAMg_model_17734.3 5 KEGG: 00860+4.2.1.24;MetaCyc: PWY-5188;Reactome: R-HSA-6798695;MetaCyc: PWY-5189;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Neutrophil degranulation";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis" JAMg_model_4033.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_14591.2 22 Reactome: R-HSA-432142;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-195253;Reactome: R-HSA-6811558;Reactome: R-HSA-196299;Reactome: R-HSA-5673000;Reactome: R-HSA-5467340;Reactome: R-HSA-389513;Reactome: R-HSA-5467348;Reactome: R-HSA-5358752;Reactome: R-HSA-68877;Reactome: R-HSA-5467337;Reactome: R-HSA-5675221;Reactome: R-HSA-5358749;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-2467813;Reactome: R-HSA-5358747 "Platelet sensitization by LDL";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Degradation of beta-catenin by the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Beta-catenin phosphorylation cascade";"RAF activation";"AXIN missense mutants destabilize the destruction complex";"CTLA4 inhibitory signaling";"Truncations of AMER1 destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"APC truncation mutants have impaired AXIN binding";"Negative regulation of MAPK pathway";"S37 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Separation of Sister Chromatids";"S33 mutants of beta-catenin aren't phosphorylated" JAMg_model_10447.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" JAMg_model_19402.1 4 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis" JAMg_model_8711.1 14 Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-203927;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593 "Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"MicroRNA (miRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity" JAMg_model_7723.2 3 Reactome: R-HSA-420029;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" JAMg_model_20857.2 14 KEGG: 00770+2.6.1.42;KEGG: 00290+2.6.1.42;Reactome: R-HSA-70895;KEGG: 00280+2.6.1.42;MetaCyc: PWY-7767;MetaCyc: PWY-5104;MetaCyc: PWY-5078;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5103;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5108;MetaCyc: PWY-5101;MetaCyc: PWY-5076;MetaCyc: PWY-5057 "Pantothenate and CoA biosynthesis";"Valine, leucine and isoleucine biosynthesis";"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis IV";"L-isoleucine degradation II";"Glucosinolate biosynthesis";"L-isoleucine biosynthesis III";"Cysteine and methionine metabolism";"L-isoleucine biosynthesis V";"L-isoleucine biosynthesis II";"L-leucine degradation III";"L-valine degradation II" JAMg_model_11108.2 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" JAMg_model_5284.4 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" JAMg_model_16435.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706 "Peptide chain elongation";"Viral mRNA Translation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit" JAMg_model_20500.1 2 Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286 "Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism" JAMg_model_11229.1 9 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"Human immunodeficiency virus 1 infection" JAMg_model_14445.2 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" JAMg_model_13429.1 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" JAMg_model_1151.7 1 Reactome: R-HSA-8950505 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" JAMg_model_4426.2 2 Reactome: R-HSA-8949215;Reactome: R-HSA-983231 "Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production" JAMg_model_3318.2 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" JAMg_model_9775.1 5 Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-73772 "NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape" JAMg_model_6599.3 1 Reactome: R-HSA-189200 "Cellular hexose transport" JAMg_model_1710.1 56 Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-4641257;Reactome: R-HSA-174084 "ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Interleukin-1 signaling";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"UCH proteinases";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C" JAMg_model_7752.2 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" JAMg_model_5146.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" JAMg_model_11303.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" JAMg_model_13506.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" JAMg_model_10134.7 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" JAMg_model_8550.6 14 MetaCyc: PWY-5972;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7601 "Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" JAMg_model_10639.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" JAMg_model_216.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" JAMg_model_18918.1 3 KEGG: 00620+4.4.1.5;MetaCyc: PWY-5386;Reactome: R-HSA-70268 "Pyruvate metabolism";"Methylglyoxal degradation I";"Pyruvate metabolism" JAMg_model_7604.1 7 Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-1362277 "Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex" JAMg_model_6621.1 25 Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-380270;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-9648025 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"HCMV Early Events";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation" JAMg_model_6961.1 2 Reactome: R-HSA-2672351;KEGG: 00970+6.1.1.3 "Stimuli-sensing channels";"Aminoacyl-tRNA biosynthesis" JAMg_model_3020.2 1 Reactome: R-HSA-611105 "Respiratory electron transport" JAMg_model_15390.3 33 Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-68877;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-1169408;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-168333 "Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Mitotic Prometaphase";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery" JAMg_model_8172.1 2 Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22 "Fatty acyl-CoA biosynthesis";"Fatty acid elongation" JAMg_model_8212.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_4173.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" JAMg_model_3184.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_12588.1 13 Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-177504;Reactome: R-HSA-8964038;Reactome: R-HSA-3928665;Reactome: R-HSA-182218;Reactome: R-HSA-8866427;Reactome: R-HSA-416993;Reactome: R-HSA-2132295;Reactome: R-HSA-167590;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-437239 "WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Retrograde neurotrophin signalling";"LDL clearance";"EPH-ephrin mediated repulsion of cells";"Nef Mediated CD8 Down-regulation";"VLDLR internalisation and degradation";"Trafficking of GluR2-containing AMPA receptors";"MHC class II antigen presentation";"Nef Mediated CD4 Down-regulation";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Recycling pathway of L1" JAMg_model_8302.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-156588 "Antimicrobial peptides";"Glucuronidation" JAMg_model_20463.1 7 MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-7445 "Matairesinol biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation" JAMg_model_20944.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" JAMg_model_9819.2 6 Reactome: R-HSA-8868766;MetaCyc: PWY-6829;Reactome: R-HSA-6787450;Reactome: R-HSA-6785470;MetaCyc: PWY-7285;MetaCyc: PWY-7286 "rRNA processing in the mitochondrion";"Trna methylation (yeast)";"tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion";"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis" JAMg_model_15284.1 12 MetaCyc: PWY-7230;MetaCyc: PWY-6708;MetaCyc: PWY-5855;MetaCyc: PWY-5873;MetaCyc: PWY-5871;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5872;Reactome: R-HSA-2142789;MetaCyc: PWY-5870;MetaCyc: PWY-5856;MetaCyc: PWY-5857;MetaCyc: PWY-7233 "Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)" JAMg_model_20205.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" JAMg_model_13220.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_4282.1 4 Reactome: R-HSA-1614558;KEGG: 00270+1.13.11.20;MetaCyc: PWY-5331;KEGG: 00430+1.13.11.20 "Degradation of cysteine and homocysteine";"Cysteine and methionine metabolism";"Taurine biosynthesis I";"Taurine and hypotaurine metabolism" JAMg_model_14494.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_5645.2 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" JAMg_model_13521.3 8 Reactome: R-HSA-442720;Reactome: R-HSA-164378;Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-5610787 "CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"DARPP-32 events";"Hedgehog 'off' state" JAMg_model_17698.1 1 Reactome: R-HSA-163765 "ChREBP activates metabolic gene expression" JAMg_model_10193.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" JAMg_model_15852.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" JAMg_model_17133.1 33 Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-141444;Reactome: R-HSA-4085377;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-68877;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690 "Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of SUMOylation proteins";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Mitotic Prometaphase";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events" JAMg_model_1629.4 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" JAMg_model_18382.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" JAMg_model_20577.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_7995.5 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" JAMg_model_15769.1 1 Reactome: R-HSA-975578 "Reactions specific to the complex N-glycan synthesis pathway" JAMg_model_3072.1 2 Reactome: R-HSA-167827;Reactome: R-HSA-167826 "The proton buffering model";"The fatty acid cycling model" JAMg_model_19440.1 7 KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-7039;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6367 "Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism" JAMg_model_5874.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_12573.1 18 KEGG: 00620+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-5392;KEGG: 00630+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-7115;KEGG: 00710+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-5690;Reactome: R-HSA-70263;MetaCyc: PWY-7383;KEGG: 00020+1.1.1.37;MetaCyc: PWY-561;KEGG: 00720+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-6969 "Pyruvate metabolism";"Methane metabolism";"Methylaspartate cycle";"Reductive TCA cycle II";"Glyoxylate and dicarboxylate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation I (serine pathway)";"TCA cycle II (plants and fungi)";"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Cysteine and methionine metabolism";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" JAMg_model_9310.4 4 Reactome: R-HSA-499943;Reactome: R-HSA-2161541;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" JAMg_model_11395.2 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" JAMg_model_1985.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" JAMg_model_16345.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_19616.1 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" JAMg_model_11967.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" JAMg_model_15508.3 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" JAMg_model_15941.1 1 Reactome: R-HSA-376172 "DSCAM interactions" JAMg_model_13958.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" JAMg_model_18681.6 1 KEGG: 00230+4.6.1.2 "Purine metabolism" JAMg_model_11277.1 3 Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691 "Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" JAMg_model_21247.2 4 Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695 "Cargo concentration in the ER";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Neutrophil degranulation" JAMg_model_7683.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" JAMg_model_20594.1 10 Reactome: R-HSA-427413;Reactome: R-HSA-9022538;Reactome: R-HSA-983231;Reactome: R-HSA-9022699;Reactome: R-HSA-9022702;Reactome: R-HSA-9615017;Reactome: R-HSA-8936459;Reactome: R-HSA-400206;Reactome: R-HSA-3899300;Reactome: R-HSA-9022692 "NoRC negatively regulates rRNA expression";"Loss of MECP2 binding ability to 5mC-DNA";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates neuronal receptors and channels";"MECP2 regulates transcription of neuronal ligands";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of lipid metabolism by PPARalpha";"SUMOylation of transcription cofactors";"Regulation of MECP2 expression and activity" JAMg_model_1522.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-171319 "HATs acetylate histones";"Telomere Extension By Telomerase" JAMg_model_13538.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-400511 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)" JAMg_model_11252.6 9 KEGG: 00564+1.1.1.8;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7385;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-7902;MetaCyc: PWY-6118;MetaCyc: PWY-5981 "Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Glucosylglycerol biosynthesis";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis III" JAMg_model_2448.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" JAMg_model_10689.2 6 Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513 "KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" JAMg_model_8637.1 4 KEGG: 00513+2.4.1.261;Reactome: R-HSA-4720454;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.259+2.4.1.261 "Various types of N-glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis" JAMg_model_17365.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" JAMg_model_14651.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" JAMg_model_12385.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" JAMg_model_10807.1 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_17671.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" JAMg_model_10992.8 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" JAMg_model_5921.2 6 Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-390450 "Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC" JAMg_model_15724.1 3 Reactome: R-HSA-1442490;Reactome: R-HSA-1592389;Reactome: R-HSA-1474228 "Collagen degradation";"Activation of Matrix Metalloproteinases";"Degradation of the extracellular matrix" JAMg_model_2208.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" JAMg_model_20857.1 14 MetaCyc: PWY-5104;MetaCyc: PWY-7767;KEGG: 00290+2.6.1.42;Reactome: R-HSA-70895;KEGG: 00280+2.6.1.42;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5078;KEGG: 00270+2.6.1.42;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5103;MetaCyc: PWY-5057;MetaCyc: PWY-5076;MetaCyc: PWY-5101;MetaCyc: PWY-5108 "L-isoleucine biosynthesis IV";"L-leucine degradation IV (Stickland reaction)";"Valine, leucine and isoleucine biosynthesis";"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation";"Pantothenate and CoA biosynthesis";"L-isoleucine degradation II";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis";"L-isoleucine biosynthesis III";"L-valine degradation II";"L-leucine degradation III";"L-isoleucine biosynthesis II";"L-isoleucine biosynthesis V" JAMg_model_20594.3 10 Reactome: R-HSA-9022699;Reactome: R-HSA-9022702;Reactome: R-HSA-983231;Reactome: R-HSA-427413;Reactome: R-HSA-9022538;Reactome: R-HSA-9022692;Reactome: R-HSA-3899300;Reactome: R-HSA-8936459;Reactome: R-HSA-9615017;Reactome: R-HSA-400206 "MECP2 regulates neuronal receptors and channels";"MECP2 regulates transcription of neuronal ligands";"Factors involved in megakaryocyte development and platelet production";"NoRC negatively regulates rRNA expression";"Loss of MECP2 binding ability to 5mC-DNA";"Regulation of MECP2 expression and activity";"SUMOylation of transcription cofactors";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of lipid metabolism by PPARalpha" JAMg_model_8897.1 3 Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-1268020 "Complex I biogenesis";"Respiratory electron transport";"Mitochondrial protein import" JAMg_model_6264.1 12 KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7416;MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4 "Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Plasmalogen degradation";"alpha-Linolenic acid metabolism" JAMg_model_850.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" JAMg_model_11463.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" JAMg_model_6585.1 7 Reactome: R-HSA-5696395;Reactome: R-HSA-5685939;Reactome: R-HSA-5696400;Reactome: R-HSA-110362;Reactome: R-HSA-5696394;Reactome: R-HSA-2173795;Reactome: R-HSA-3108214 "Formation of Incision Complex in GG-NER";"HDR through MMEJ (alt-NHEJ)";"Dual Incision in GG-NER";"POLB-Dependent Long Patch Base Excision Repair";"DNA Damage Recognition in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"SUMOylation of DNA damage response and repair proteins" JAMg_model_18110.2 14 MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7035 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis" JAMg_model_8298.13 4 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-1912420 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi" JAMg_model_4958.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_7979.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" JAMg_model_20430.3 1 Reactome: R-HSA-189200 "Cellular hexose transport" JAMg_model_1106.2 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_11820.1 5 Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-6814122 "Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" JAMg_model_3505.2 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" JAMg_model_9396.2 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" JAMg_model_9544.1 1 Reactome: R-HSA-6804760 "Regulation of TP53 Activity through Methylation" JAMg_model_12664.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" JAMg_model_11784.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" JAMg_model_5689.3 2 Reactome: R-HSA-191859;Reactome: R-HSA-6807505 "snRNP Assembly";"RNA polymerase II transcribes snRNA genes" JAMg_model_6780.1 5 Reactome: R-HSA-3769402;Reactome: R-HSA-3214841;Reactome: R-HSA-201722;Reactome: R-HSA-5617472;Reactome: R-HSA-8936459 "Deactivation of the beta-catenin transactivating complex";"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" JAMg_model_14657.2 4 Reactome: R-HSA-8939211;Reactome: R-HSA-3371497;Reactome: R-HSA-9018519;Reactome: R-HSA-3371568 "ESR-mediated signaling";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Estrogen-dependent gene expression";"Attenuation phase" JAMg_model_12160.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" JAMg_model_6952.1 6 Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68867 "Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex" JAMg_model_11140.1 16 Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-179409 "Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A" JAMg_model_1482.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" JAMg_model_2111.1 5 MetaCyc: PWY-7177;Reactome: R-HSA-499943;MetaCyc: PWY-7185;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7176 "UTP and CTP dephosphorylation II";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis" JAMg_model_20334.7 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" JAMg_model_12721.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase" JAMg_model_8560.1 24 Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497 "Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"Mitotic Prometaphase";"HCMV Early Events";"Kinesins";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Aggrephagy";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" JAMg_model_18895.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" JAMg_model_12988.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" JAMg_model_4168.1 22 MetaCyc: PWY-5080;MetaCyc: PWY-7049;MetaCyc: PWY-7602;MetaCyc: PWY-6433;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7053;MetaCyc: PWY-5353;MetaCyc: PWY-7606;MetaCyc: PWY-6958;MetaCyc: PWY-7726;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7727;MetaCyc: PWY-7592;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7728;MetaCyc: PWY-8041 "Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Ultra-long-chain fatty acid biosynthesis" JAMg_model_17937.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" JAMg_model_3949.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" JAMg_model_19308.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975957 "Viral mRNA Translation";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" JAMg_model_2960.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" JAMg_model_9837.1 8 KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" JAMg_model_3080.1 7 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway" JAMg_model_3435.3 6 Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-429958 "Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease" JAMg_model_15087.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_17561.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257 "Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion" JAMg_model_11061.1 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" JAMg_model_11511.1 7 Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2;Reactome: R-HSA-5628897;Reactome: R-HSA-210500;MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2 "Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"TP53 Regulates Metabolic Genes";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism" JAMg_model_148.3 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_18499.1 2 KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" JAMg_model_10036.1 4 Reactome: R-HSA-446193;Reactome: R-HSA-4720475;KEGG: 00513+2.4.1.258;KEGG: 00510+2.4.1.258 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG3 causes ALG3-CDG (CDG-1d)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis" JAMg_model_1970.4 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_7282.1 24 Reactome: R-HSA-163358;Reactome: R-HSA-9634600;Reactome: R-HSA-5610787;Reactome: R-HSA-8853659;Reactome: R-HSA-163560;Reactome: R-HSA-432040;Reactome: R-HSA-9010642;Reactome: R-HSA-442720;Reactome: R-HSA-164378;Reactome: R-HSA-8963896;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-4420097;Reactome: R-HSA-180024;Reactome: R-HSA-392517;Reactome: R-HSA-5687128;Reactome: R-HSA-111931;KEGG: 04150+2.7.11.11;Reactome: R-HSA-5610785;Reactome: R-HSA-5621575;Reactome: R-HSA-5610780;Reactome: R-HSA-983231;Reactome: R-HSA-5610783;Reactome: R-HSA-422356 "PKA-mediated phosphorylation of key metabolic factors";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Hedgehog 'off' state";"RET signaling";"Triglyceride catabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"ROBO receptors bind AKAP5";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling";"HDL assembly";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"VEGFA-VEGFR2 Pathway";"DARPP-32 events";"Rap1 signalling";"MAPK6/MAPK4 signaling";"PKA-mediated phosphorylation of CREB";"mTOR signaling pathway";"GLI3 is processed to GLI3R by the proteasome";"CD209 (DC-SIGN) signaling";"Degradation of GLI1 by the proteasome";"Factors involved in megakaryocyte development and platelet production";"Degradation of GLI2 by the proteasome";"Regulation of insulin secretion" JAMg_model_1574.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" JAMg_model_8725.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" JAMg_model_13027.1 7 Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-1442490;Reactome: R-HSA-2894862;Reactome: R-HSA-177929;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232 "Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants" JAMg_model_17427.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004 "Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity" JAMg_model_12646.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" JAMg_model_20707.2 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" JAMg_model_10246.5 13 KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;Reactome: R-HSA-2022857;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52 "Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Keratan sulfate degradation";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation" JAMg_model_13380.2 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" JAMg_model_6835.2 2 Reactome: R-HSA-5658442;Reactome: R-HSA-6802953 "Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants" JAMg_model_8106.1 4 Reactome: R-HSA-112043;Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "PLC beta mediated events";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" JAMg_model_13244.2 7 Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2 "Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism" JAMg_model_16999.2 8 Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-3371571;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288 "Regulation of PTEN gene transcription";"Macroautophagy";"mTOR signalling";"HSF1-dependent transactivation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1" JAMg_model_18156.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" JAMg_model_15870.6 8 KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1 "Galactose metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Glycolysis";"Amino sugar and nucleotide sugar metabolism" JAMg_model_4405.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-2022377 "Neutrophil degranulation";"Metabolism of Angiotensinogen to Angiotensins" JAMg_model_3208.2 5 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination" JAMg_model_8393.4 2 Reactome: R-HSA-2408508;Reactome: R-HSA-389661 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation" JAMg_model_3581.1 57 Reactome: R-HSA-5687128;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870 "MAPK6/MAPK4 signaling";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"UCH proteinases";"FCERI mediated NF-kB activation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"Neutrophil degranulation";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins" JAMg_model_11982.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" JAMg_model_8926.1 1 Reactome: R-HSA-6798163 "Choline catabolism" JAMg_model_7216.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_9164.2 2 KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281 "Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" JAMg_model_17299.2 11 MetaCyc: PWY-7456;MetaCyc: PWY-5659;MetaCyc: PWY-882;MetaCyc: PWY-3861;MetaCyc: PWY-6992;MetaCyc: PWY-7586;KEGG: 00051+5.3.1.8;Reactome: R-HSA-4043916;Reactome: R-HSA-446205;MetaCyc: PWY-3881;KEGG: 00520+5.3.1.8 "Beta-(1,4)-mannan degradation";"GDP-mannose biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Mannitol degradation II";"1,5-anhydrofructose degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Fructose and mannose metabolism";"Defective MPI causes MPI-CDG (CDG-1b)";"Synthesis of GDP-mannose";"Mannitol biosynthesis";"Amino sugar and nucleotide sugar metabolism" JAMg_model_2446.4 5 Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-6804758 "RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation" JAMg_model_21029.3 15 Reactome: R-HSA-4641262;Reactome: R-HSA-5467340;Reactome: R-HSA-5358747;Reactome: R-HSA-3769402;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-5467333;Reactome: R-HSA-5467337;Reactome: R-HSA-5689896;Reactome: R-HSA-195253;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-111465;Reactome: R-HSA-5358752;Reactome: R-HSA-5339716 "Disassembly of the destruction complex and recruitment of AXIN to the membrane";"AXIN missense mutants destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"APC truncation mutants have impaired AXIN binding";"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Apoptotic cleavage of cellular proteins";"T41 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin" JAMg_model_7374.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" JAMg_model_14652.2 13 Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation" JAMg_model_18918.2 3 KEGG: 00620+4.4.1.5;MetaCyc: PWY-5386;Reactome: R-HSA-70268 "Pyruvate metabolism";"Methylglyoxal degradation I";"Pyruvate metabolism" JAMg_model_11686.1 7 Reactome: R-HSA-983170;Reactome: R-HSA-3371453;Reactome: R-HSA-381183;Reactome: R-HSA-381070;Reactome: R-HSA-114608;Reactome: R-HSA-381042;Reactome: R-HSA-381033 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of HSF1-mediated heat shock response";"ATF6 (ATF6-alpha) activates chaperone genes";"IRE1alpha activates chaperones";"Platelet degranulation";"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperones" JAMg_model_1909.3 1 Reactome: R-HSA-8949664 "Processing of SMDT1" JAMg_model_15574.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" JAMg_model_9481.1 8 Reactome: R-HSA-983712;Reactome: R-HSA-182218;Reactome: R-HSA-9636467;Reactome: R-HSA-1222556;Reactome: R-HSA-167590;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-9639288 "Ion channel transport";"Nef Mediated CD8 Down-regulation";"Blockage of phagosome acidification";"ROS and RNS production in phagocytes";"Nef Mediated CD4 Down-regulation";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Amino acids regulate mTORC1" JAMg_model_434.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84 "Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis" JAMg_model_11749.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" JAMg_model_1505.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" JAMg_model_17775.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" JAMg_model_8910.6 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" JAMg_model_10547.3 6 Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins" JAMg_model_12162.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" JAMg_model_7918.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" JAMg_model_11090.2 4 Reactome: R-HSA-8874211;Reactome: R-HSA-381033;Reactome: R-HSA-8963889;Reactome: R-HSA-1655829 "CREB3 factors activate genes";"ATF6 (ATF6-alpha) activates chaperones";"Assembly of active LPL and LIPC lipase complexes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" JAMg_model_13145.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" JAMg_model_1489.2 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" JAMg_model_6807.5 5 KEGG: 00720+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00630+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33 "Carbon fixation pathways in prokaryotes";"Iron uptake and transport";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis" JAMg_model_11399.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_3074.3 2 Reactome: R-HSA-6803205;Reactome: R-HSA-8873719 "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation" JAMg_model_13099.2 3 MetaCyc: PWY-7807;MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1 "Glyphosate degradation III";"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation" JAMg_model_16400.3 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" JAMg_model_1255.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" JAMg_model_16323.1 5 Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681;MetaCyc: PWY-7511;Reactome: R-HSA-8948751 "Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT";"Protein ubiquitination";"Regulation of PTEN stability and activity" JAMg_model_3864.2 3 MetaCyc: PWY-7159;KEGG: 00860+1.3.3.4;Reactome: R-HSA-189451 "3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis" JAMg_model_8550.7 14 MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7725 "Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)" JAMg_model_7014.2 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_17035.1 7 Reactome: R-HSA-74259;Reactome: R-HSA-194840;MetaCyc: PWY-7442;MetaCyc: PWY-5497;MetaCyc: PWY-6608;KEGG: 00230+3.5.4.3;MetaCyc: PWY-6606 "Purine catabolism";"Rho GTPase cycle";"Drosopterin and aurodrosopterin biosynthesis";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation III";"Purine metabolism";"Guanosine nucleotides degradation II" JAMg_model_2563.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_19317.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_9600.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6798695 "COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation" JAMg_model_19213.4 3 Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51 "Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation" JAMg_model_3367.1 6 Reactome: R-HSA-5632684;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-201722;Reactome: R-HSA-674695 "Hedgehog 'on' state";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Pre-transcription Events" JAMg_model_16890.1 1 Reactome: R-HSA-74217 "Purine salvage" JAMg_model_20037.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" JAMg_model_3663.5 5 KEGG: 00983+2.7.1.21;KEGG: 00240+2.7.1.21;MetaCyc: PWY-7199;Reactome: R-HSA-69205;Reactome: R-HSA-73614 "Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides salvage";"G1/S-Specific Transcription";"Pyrimidine salvage" JAMg_model_7864.5 3 Reactome: R-HSA-983189;Reactome: R-HSA-390471;Reactome: R-HSA-6811434 "Kinesins";"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_2280.7 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" JAMg_model_1902.1 1 Reactome: R-HSA-6798163 "Choline catabolism" JAMg_model_9965.2 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" JAMg_model_7489.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_8077.1 5 Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568 "Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates" JAMg_model_10021.3 4 Reactome: R-HSA-1855183;MetaCyc: PWY-4841;KEGG: 00562+1.13.99.1;KEGG: 00053+1.13.99.1 "Synthesis of IP2, IP, and Ins in the cytosol";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Inositol phosphate metabolism";"Ascorbate and aldarate metabolism" JAMg_model_5874.5 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_9311.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" JAMg_model_18090.1 3 Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" JAMg_model_4502.1 16 Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693548;Reactome: R-HSA-201722;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-9018519;Reactome: R-HSA-5693571;Reactome: R-HSA-5693568;Reactome: R-HSA-3214847;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-2559586;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565 "G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Sensing of DNA Double Strand Breaks";"Formation of the beta-catenin:TCF transactivating complex";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Estrogen-dependent gene expression";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HATs acetylate histones";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"DNA Damage/Telomere Stress Induced Senescence";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" JAMg_model_8783.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" JAMg_model_5841.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" JAMg_model_6618.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_7088.2 3 KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369 "Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis" JAMg_model_12965.1 4 Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport" JAMg_model_1536.1 9 Reactome: R-HSA-166208;Reactome: R-HSA-6798695;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-5674135;Reactome: R-HSA-5628897 "mTORC1-mediated signalling";"Neutrophil degranulation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"MAP2K and MAPK activation";"TP53 Regulates Metabolic Genes" JAMg_model_4800.2 27 Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408 "Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism" JAMg_model_5978.3 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" JAMg_model_5091.1 16 KEGG: 00010+4.2.1.11;MetaCyc: PWY-6142;MetaCyc: PWY-2221;MetaCyc: PWY-7124;MetaCyc: PWY-7218;MetaCyc: PWY-1042;MetaCyc: PWY-6901;KEGG: 00680+4.2.1.11;MetaCyc: PWY-7003;Reactome: R-HSA-70171;MetaCyc: PWY-5723;Reactome: R-HSA-70263;MetaCyc: PWY-6886;MetaCyc: PWY-8004;MetaCyc: PWY-1622;MetaCyc: PWY-5484 "Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Ethylene biosynthesis V (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Methane metabolism";"Glycerol degradation to butanol";"Glycolysis";"Rubisco shunt";"Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)";"Glycolysis II (from fructose 6-phosphate)" JAMg_model_43.1 5 Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084 "Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA" JAMg_model_19062.1 8 MetaCyc: PWY-6922;Reactome: R-HSA-70688;Reactome: R-HSA-1442490;MetaCyc: PWY-5737;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;KEGG: 00330+1.5.5.2 "L-Ndelta-acetylornithine biosynthesis";"Proline catabolism";"Collagen degradation";"(5R)-carbapenem carboxylate biosynthesis";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Arginine and proline metabolism" JAMg_model_3655.2 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" JAMg_model_4828.4 3 Reactome: R-HSA-525793;Reactome: R-HSA-5663220;Reactome: R-HSA-9634638 "Myogenesis";"RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling" JAMg_model_11034.3 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" JAMg_model_9141.3 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" JAMg_model_5587.2 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" JAMg_model_18440.5 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" JAMg_model_6333.5 10 MetaCyc: PWY-5839;MetaCyc: PWY-5890;MetaCyc: PWY-5849;Reactome: R-HSA-2142789;MetaCyc: PWY-5891;KEGG: 00130+2.1.1.163;MetaCyc: PWY-7996;MetaCyc: PWY-5895;MetaCyc: PWY-5844;MetaCyc: PWY-5892 "Menaquinol-7 biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-6 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-11 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-13 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-12 biosynthesis" JAMg_model_830.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339 "Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane" JAMg_model_14313.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" JAMg_model_5470.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_7199.1 2 KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23 "Drug metabolism - other enzymes";"Pyrimidine metabolism" JAMg_model_2280.4 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" JAMg_model_19013.1 7 Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;MetaCyc: PWY-7511;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232 "Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants" JAMg_model_17734.1 5 Reactome: R-HSA-189451;MetaCyc: PWY-5189;Reactome: R-HSA-6798695;KEGG: 00860+4.2.1.24;MetaCyc: PWY-5188 "Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Neutrophil degranulation";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)" JAMg_model_15895.2 7 Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-5628897 "Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Macroautophagy";"mTOR signalling";"TP53 Regulates Metabolic Genes" JAMg_model_11737.7 1 Reactome: R-HSA-400253 "Circadian Clock" JAMg_model_14642.1 2 Reactome: R-HSA-525793;Reactome: R-HSA-373752 "Myogenesis";"Netrin-1 signaling" JAMg_model_326.2 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_11379.2 3 Reactome: R-HSA-429947;Reactome: R-HSA-380994;Reactome: R-HSA-450604 "Deadenylation of mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA" JAMg_model_9279.2 10 Reactome: R-HSA-381042;Reactome: R-HSA-72649;Reactome: R-HSA-9648895;Reactome: R-HSA-9633012;Reactome: R-HSA-382556;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72731;Reactome: R-HSA-156827 "PERK regulates gene expression";"Translation initiation complex formation";"Response of EIF2AK1 (HRI) to heme deficiency";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ABC-family proteins mediated transport";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Recycling of eIF2:GDP";"L13a-mediated translational silencing of Ceruloplasmin expression" JAMg_model_4262.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" JAMg_model_20955.2 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_1643.2 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" JAMg_model_12909.1 6 KEGG: 00930+3.1.1.17;MetaCyc: PWY-5530;KEGG: 00053+3.1.1.17;MetaCyc: PWY-2221;MetaCyc: PWY-7165;KEGG: 00030+3.1.1.17 "Caprolactam degradation";"Sorbitol biosynthesis II";"Ascorbate and aldarate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"L-ascorbate biosynthesis VI (engineered pathway)";"Pentose phosphate pathway" JAMg_model_11652.1 6 KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-5530;MetaCyc: PWY-7165;KEGG: 00030+3.1.1.17;MetaCyc: PWY-2221 "Caprolactam degradation";"Ascorbate and aldarate metabolism";"Sorbitol biosynthesis II";"L-ascorbate biosynthesis VI (engineered pathway)";"Pentose phosphate pathway";"Entner-Doudoroff pathway III (semi-phosphorylative)" JAMg_model_13366.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_2867.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_7933.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" JAMg_model_13193.1 3 MetaCyc: PWY-7831;Reactome: R-HSA-9033807;MetaCyc: PWY-7833 "ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)" JAMg_model_15645.1 7 Reactome: R-HSA-5083628;Reactome: R-HSA-5173105;Reactome: R-HSA-3000178;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-9010553;Reactome: R-HSA-5083633 "Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation";"ECM proteoglycans";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"Regulation of expression of SLITs and ROBOs";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1" JAMg_model_12934.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" JAMg_model_6481.2 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" JAMg_model_20249.2 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" JAMg_model_11303.2 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" JAMg_model_17691.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712 "Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport" JAMg_model_9126.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" JAMg_model_13435.3 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_3037.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes" JAMg_model_8191.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" JAMg_model_21022.8 13 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72706 "Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit" JAMg_model_19465.2 30 Reactome: R-HSA-8939902;Reactome: R-HSA-917937;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-2122947;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-1170546;Reactome: R-HSA-187577;Reactome: R-HSA-2565942;Reactome: R-HSA-195253;Reactome: R-HSA-5684264;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-2644607;Reactome: R-HSA-400253;Reactome: R-HSA-2894862;Reactome: R-HSA-5607764;Reactome: R-HSA-69231;Reactome: R-HSA-2644606 "Regulation of RUNX2 expression and activity";"Iron uptake and transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"NOTCH1 Intracellular Domain Regulates Transcription";"NIK-->noncanonical NF-kB signaling";"Neddylation";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"Prolactin receptor signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of PLK1 Activity at G2/M Transition";"Degradation of beta-catenin by the destruction complex";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Circadian Clock";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"CLEC7A (Dectin-1) signaling";"Cyclin D associated events in G1";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" JAMg_model_16874.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" JAMg_model_20943.1 2 Reactome: R-HSA-156588;Reactome: R-HSA-6798163 "Glucuronidation";"Choline catabolism" JAMg_model_8084.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" JAMg_model_21325.2 1 Reactome: R-HSA-2024096 "HS-GAG degradation" JAMg_model_12919.4 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_997.6 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" JAMg_model_4337.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" JAMg_model_907.5 8 Reactome: R-HSA-190873;Reactome: R-HSA-432720;Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-196025 "Gap junction degradation";"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Formation of annular gap junctions" JAMg_model_4814.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689 "SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" JAMg_model_209.1 2 KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859 "Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade" JAMg_model_19737.1 14 MetaCyc: PWY-7783;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;Reactome: R-HSA-975634;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7409;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4 "Plasmalogen degradation";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Retinoid metabolism and transport";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism" JAMg_model_3086.1 14 Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-1251985;Reactome: R-HSA-977225;Reactome: R-HSA-193692;Reactome: R-HSA-2979096;Reactome: R-HSA-3928665;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-2122948;Reactome: R-HSA-1474228;Reactome: R-HSA-6798695;Reactome: R-HSA-2644606 "Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"Nuclear signaling by ERBB4";"Amyloid fiber formation";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Degradation of the extracellular matrix";"Neutrophil degranulation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" JAMg_model_6358.1 2 Reactome: R-HSA-174403;Reactome: R-HSA-5578999 "Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)" JAMg_model_5433.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling" JAMg_model_20249.4 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" JAMg_model_4381.2 5 Reactome: R-HSA-5696400;Reactome: R-HSA-5685938;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-6783310 "Dual Incision in GG-NER";"HDR through Single Strand Annealing (SSA)";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Fanconi Anemia Pathway" JAMg_model_5924.4 3 Reactome: R-HSA-8951664;MetaCyc: PWY-7511;Reactome: R-HSA-349425 "Neddylation";"Protein ubiquitination";"Autodegradation of the E3 ubiquitin ligase COP1" JAMg_model_19036.1 11 Reactome: R-HSA-71403;MetaCyc: PWY-6549;MetaCyc: PWY-7254;KEGG: 00720+1.1.1.42;MetaCyc: PWY-5913;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-7268;MetaCyc: PWY-7124;KEGG: 00480+1.1.1.42 "Citric acid cycle (TCA cycle)";"L-glutamine biosynthesis III";"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Ethylene biosynthesis V (engineered)";"Glutathione metabolism" JAMg_model_8944.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" JAMg_model_12131.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_16392.2 6 Reactome: R-HSA-8936459;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-8951664 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Neddylation" JAMg_model_4893.2 12 Reactome: R-HSA-73817;MetaCyc: PWY-6613;KEGG: 00670+2.1.2.2;MetaCyc: PWY-6121;MetaCyc: PWY-6277;KEGG: 00230+2.1.2.2;Reactome: R-HSA-196780;KEGG: 00230+6.3.4.13;KEGG: 00230+6.3.3.1;MetaCyc: PWY-6122;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9 "Purine ribonucleoside monophosphate biosynthesis";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"One carbon pool by folate";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"Biotin transport and metabolism";"Purine metabolism";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis" JAMg_model_1645.1 6 KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23 "Galactose metabolism";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation" JAMg_model_3646.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" JAMg_model_16384.1 4 MetaCyc: PWY-7494;Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722 "Choline degradation IV";"Choline catabolism";"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)" JAMg_model_5921.4 6 Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390471 "Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis" JAMg_model_15505.3 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" JAMg_model_907.14 8 Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-432720;Reactome: R-HSA-190873 "Formation of annular gap junctions";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"Lysosome Vesicle Biogenesis";"Gap junction degradation" JAMg_model_21117.1 5 MetaCyc: PWY-5381;Reactome: R-HSA-196807;MetaCyc: PWY-7761;MetaCyc: PWY-5653;KEGG: 00760+2.7.7.18 "Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism" JAMg_model_19081.2 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" JAMg_model_17589.1 8 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"T cell receptor signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway" JAMg_model_742.2 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" JAMg_model_12126.1 5 Reactome: R-HSA-2426168;Reactome: R-HSA-75105;Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-9029558 "Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis";"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis" JAMg_model_12579.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" JAMg_model_1229.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_21260.5 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" JAMg_model_3606.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" JAMg_model_17881.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" JAMg_model_13553.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_11757.2 6 Reactome: R-HSA-8874211;Reactome: R-HSA-381033;Reactome: R-HSA-381426;Reactome: R-HSA-8963889;Reactome: R-HSA-8957275;Reactome: R-HSA-1655829 "CREB3 factors activate genes";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Assembly of active LPL and LIPC lipase complexes";"Post-translational protein phosphorylation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" JAMg_model_4200.1 1 Reactome: R-HSA-5689603 "UCH proteinases" JAMg_model_4737.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-1632852;Reactome: R-HSA-8854214;Reactome: R-HSA-380972 "TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"Macroautophagy";"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK" JAMg_model_5167.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733 "Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis" JAMg_model_18660.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane" JAMg_model_13397.4 7 KEGG: 00564+2.7.1.32+2.7.1.82;Reactome: R-HSA-1483213;MetaCyc: PWY-7818;MetaCyc: PWY-7886;Reactome: R-HSA-1483191;MetaCyc: PWY-7782;MetaCyc: PWY-3385 "Glycerophospholipid metabolism";"Synthesis of PE";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PC";"Plasmalogen biosynthesis";"Choline biosynthesis I" JAMg_model_10598.5 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5689880 "UCH proteinases";"Ub-specific processing proteases" JAMg_model_17399.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_16884.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_15399.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis" JAMg_model_15020.1 2 Reactome: R-HSA-5663220;Reactome: R-HSA-376176 "RHO GTPases Activate Formins";"Signaling by ROBO receptors" JAMg_model_17824.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_9837.2 8 KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway" JAMg_model_14663.3 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" JAMg_model_4808.4 2 Reactome: R-HSA-5689880;Reactome: R-HSA-8949215 "Ub-specific processing proteases";"Mitochondrial calcium ion transport" JAMg_model_10745.4 5 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-72187;Reactome: R-HSA-72163 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway" JAMg_model_17703.1 6 Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Neutrophil degranulation";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport" JAMg_model_1040.6 1 Reactome: R-HSA-5620924 "Intraflagellar transport" JAMg_model_1331.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" JAMg_model_4541.11 7 Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270 "AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" JAMg_model_10202.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_3090.2 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" JAMg_model_10072.2 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" JAMg_model_15423.1 1 Reactome: R-HSA-3295583 "TRP channels" JAMg_model_17152.1 10 KEGG: 04070+2.7.1.159;MetaCyc: PWY-6362;MetaCyc: PWY-6365;Reactome: R-HSA-983231;Reactome: R-HSA-1855167;Reactome: R-HSA-1855204;MetaCyc: PWY-6366;MetaCyc: PWY-6554;KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-4661 "Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"Factors involved in megakaryocyte development and platelet production";"Synthesis of pyrophosphates in the cytosol";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)" JAMg_model_1359.1 12 KEGG: 05170+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;Reactome: R-HSA-418885;Reactome: R-HSA-193648;Reactome: R-HSA-416476;KEGG: 04926+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"DCC mediated attractive signaling";"NRAGE signals death through JNK";"G alpha (q) signalling events";"Relaxin signaling pathway";"Rho GTPase cycle";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway" JAMg_model_17781.3 1 Reactome: R-HSA-611105 "Respiratory electron transport" JAMg_model_12508.4 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" JAMg_model_18471.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" JAMg_model_5232.3 1 Reactome: R-HSA-5620924 "Intraflagellar transport" JAMg_model_14270.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" JAMg_model_8049.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_21267.3 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" JAMg_model_3197.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" JAMg_model_4541.7 7 Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284 "Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome" JAMg_model_17702.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" JAMg_model_17079.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" JAMg_model_18860.4 2 Reactome: R-HSA-8854214;Reactome: R-HSA-8873719 "TBC/RABGAPs";"RAB geranylgeranylation" JAMg_model_5188.1 57 Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-180585;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-75815;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-1236978;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-350562;Reactome: R-HSA-69481;Reactome: R-HSA-382556 "Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"FCERI mediated NF-kB activation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Vif-mediated degradation of APOBEC3G";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of ornithine decarboxylase (ODC)";"G2/M Checkpoints";"ABC-family proteins mediated transport" JAMg_model_7655.2 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" JAMg_model_16020.2 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" JAMg_model_7092.3 5 MetaCyc: PWY-4981;MetaCyc: PWY-6344;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539 "L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism" JAMg_model_17214.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-975956 "Viral mRNA Translation";"Peptide chain elongation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" JAMg_model_12989.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_1523.3 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8949613 "Mitochondrial protein import";"Cristae formation" JAMg_model_17734.6 5 Reactome: R-HSA-6798695;MetaCyc: PWY-5188;KEGG: 00860+4.2.1.24;Reactome: R-HSA-189451;MetaCyc: PWY-5189 "Neutrophil degranulation";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)" JAMg_model_14776.4 2 Reactome: R-HSA-8983711;Reactome: R-HSA-909733 "OAS antiviral response";"Interferon alpha/beta signaling" JAMg_model_17734.4 5 MetaCyc: PWY-5188;KEGG: 00860+4.2.1.24;Reactome: R-HSA-6798695;MetaCyc: PWY-5189;Reactome: R-HSA-189451 "Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Neutrophil degranulation";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis" JAMg_model_19642.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" JAMg_model_13842.1 5 KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00600+3.2.1.22 "Galactose metabolism";"Glycerolipid metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Sphingolipid metabolism" JAMg_model_7074.1 1 Reactome: R-HSA-6798163 "Choline catabolism" JAMg_model_213.1 2 Reactome: R-HSA-202433;Reactome: R-HSA-376176 "Generation of second messenger molecules";"Signaling by ROBO receptors" JAMg_model_13712.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-6811434 "Class B/2 (Secretin family receptors)";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_750.4 1 Reactome: R-HSA-189200 "Cellular hexose transport" JAMg_model_19003.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_15868.1 57 Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-532668;Reactome: R-HSA-187577;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837 "Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Degradation of GLI2 by the proteasome";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"FCERI mediated NF-kB activation" JAMg_model_3217.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_4715.1 3 Reactome: R-HSA-500753;KEGG: 00240+1.3.5.2;MetaCyc: PWY-5686 "Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis I" JAMg_model_10867.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_10683.2 1 Reactome: R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" JAMg_model_17238.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_5070.4 17 MetaCyc: PWY-6611;KEGG: 00240+2.4.2.1;MetaCyc: PWY-7179-1;MetaCyc: PWY-6627;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6608;MetaCyc: PWY-5695;MetaCyc: PWY-6644;MetaCyc: PWY-7179;Reactome: R-HSA-74259;Reactome: R-HSA-74217;MetaCyc: PWY-5532;Reactome: R-HSA-6798695;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6609;MetaCyc: PWY-4202;MetaCyc: PWY-6620 "Adenine and adenosine salvage V";"Pyrimidine metabolism";"Purine deoxyribonucleosides degradation II";"Salinosporamide A biosynthesis";"Nicotinate and nicotinamide metabolism";"Guanosine nucleotides degradation III";"Inosine 5'-phosphate degradation";"Fluoroacetate and fluorothreonine biosynthesis";"Purine deoxyribonucleosides degradation I";"Purine catabolism";"Purine salvage";"Nucleoside and nucleotide degradation (archaea)";"Neutrophil degranulation";"Purine metabolism";"Adenine and adenosine salvage III";"Arsenate detoxification I (mammalian)";"Guanine and guanosine salvage" JAMg_model_20507.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" JAMg_model_4444.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex" JAMg_model_7185.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" JAMg_model_9512.1 1 Reactome: R-HSA-419771 "Opsins" JAMg_model_7791.2 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" JAMg_model_12065.1 6 Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817 "Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)" JAMg_model_4979.1 7 Reactome: R-HSA-77348;KEGG: 00280+1.3.8.7;KEGG: 00071+1.3.8.7;Reactome: R-HSA-77288;MetaCyc: PWY-7094;Reactome: R-HSA-77346;Reactome: R-HSA-1989781 "Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Valine, leucine and isoleucine degradation";"Fatty acid degradation";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Fatty acid salvage";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"PPARA activates gene expression" JAMg_model_4356.2 3 KEGG: 00510+2.4.1.265;Reactome: R-HSA-446193;Reactome: R-HSA-4724325 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)" JAMg_model_16504.1 3 MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783 "Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" JAMg_model_6807.6 5 Reactome: R-HSA-917937;KEGG: 00720+4.2.1.3;KEGG: 00630+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3 "Iron uptake and transport";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)" JAMg_model_16488.2 7 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway" JAMg_model_18299.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" JAMg_model_14382.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" JAMg_model_2777.7 14 Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-203927;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692 "Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"MicroRNA (miRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity" JAMg_model_11252.2 9 MetaCyc: PWY-6118;MetaCyc: PWY-5981;MetaCyc: PWY-7902;MetaCyc: PWY-5667;KEGG: 00564+1.1.1.8;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7385;MetaCyc: PWY-7411;Reactome: R-HSA-1483166 "Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis III";"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA" JAMg_model_19648.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" JAMg_model_15277.7 10 MetaCyc: PWY-5497;MetaCyc: PWY-2201;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;MetaCyc: PWY-5030;Reactome: R-HSA-196757;MetaCyc: PWY-3841;MetaCyc: PWY-6613;MetaCyc: PWY-7909 "Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"L-histidine degradation III";"Metabolism of folate and pterines";"Folate transformations II (plants)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)" JAMg_model_9985.1 4 Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" JAMg_model_5971.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" JAMg_model_3627.1 7 Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444 "SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" JAMg_model_6077.1 27 Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142 "SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins" JAMg_model_8477.3 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" JAMg_model_12678.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167162 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape" JAMg_model_10918.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" JAMg_model_1488.1 10 KEGG: 00052+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00030+2.7.1.11;KEGG: 00051+2.7.1.11;Reactome: R-HSA-70171 "Galactose metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Glycolysis" JAMg_model_7552.2 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" JAMg_model_3303.7 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" JAMg_model_7160.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" JAMg_model_8808.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" JAMg_model_5191.1 4 MetaCyc: PWY-7285;Reactome: R-HSA-6782315;MetaCyc: PWY-7286;MetaCyc: PWY-6829 "Methylwyosine biosynthesis";"tRNA modification in the nucleus and cytosol";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)" JAMg_model_12174.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" JAMg_model_9310.1 4 Reactome: R-HSA-2161541;Reactome: R-HSA-499943;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" JAMg_model_9454.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" JAMg_model_4575.1 16 Reactome: R-HSA-416476;Reactome: R-HSA-912631;Reactome: R-HSA-912526;Reactome: R-HSA-1433557;Reactome: R-HSA-1266695;Reactome: R-HSA-512988;Reactome: R-HSA-389357;Reactome: R-HSA-2219530;Reactome: R-HSA-194840;Reactome: R-HSA-388841;Reactome: R-HSA-114604;Reactome: R-HSA-1660499;Reactome: R-HSA-1257604;Reactome: R-HSA-8853659;Reactome: R-HSA-9009391;Reactome: R-HSA-6811558 "G alpha (q) signalling events";"Regulation of signaling by CBL";"Interleukin receptor SHC signaling";"Signaling by SCF-KIT";"Interleukin-7 signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Rho GTPase cycle";"Costimulation by the CD28 family";"GPVI-mediated activation cascade";"Synthesis of PIPs at the plasma membrane";"PIP3 activates AKT signaling";"RET signaling";"Extra-nuclear estrogen signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" JAMg_model_791.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" JAMg_model_11882.3 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" JAMg_model_11556.4 15 Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-2559580;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-9029569;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Oxidative Stress Induced Senescence";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation" JAMg_model_650.4 4 Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16 "Metabolism of polyamines";"Glutathione metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism" JAMg_model_15097.1 8 Reactome: R-HSA-182218;Reactome: R-HSA-983712;Reactome: R-HSA-167590;Reactome: R-HSA-1222556;Reactome: R-HSA-9636467;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-9639288 "Nef Mediated CD8 Down-regulation";"Ion channel transport";"Nef Mediated CD4 Down-regulation";"ROS and RNS production in phagocytes";"Blockage of phagosome acidification";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1" JAMg_model_3434.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" JAMg_model_16603.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" JAMg_model_6228.2 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" JAMg_model_6881.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" JAMg_model_11988.3 2 Reactome: R-HSA-6790901;Reactome: R-HSA-171319 "rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase" JAMg_model_363.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" JAMg_model_16558.1 15 MetaCyc: PWY-7003;Reactome: R-HSA-70171;MetaCyc: PWY-6142;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7218;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-6901;MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.40;MetaCyc: PWY-5723;MetaCyc: PWY-6886;MetaCyc: PWY-8004;MetaCyc: PWY-2221 "Glycerol degradation to butanol";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pyruvate metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Purine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Rubisco shunt";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Entner-Doudoroff pathway III (semi-phosphorylative)" JAMg_model_10854.4 6 Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607 "HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends" JAMg_model_18868.1 4 Reactome: R-HSA-72731;MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23 "Recycling of eIF2:GDP";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism" JAMg_model_8808.3 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" JAMg_model_6330.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" JAMg_model_12573.2 18 KEGG: 00630+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-5392;MetaCyc: PWY-7115;KEGG: 00680+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-6728;KEGG: 00270+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-1622;KEGG: 00710+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-7383;KEGG: 00020+1.1.1.37;MetaCyc: PWY-561 "Glyoxylate and dicarboxylate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Reductive TCA cycle II";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Methane metabolism";"Pyruvate metabolism";"Methylaspartate cycle";"Cysteine and methionine metabolism";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Formaldehyde assimilation I (serine pathway)";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation" JAMg_model_21022.9 13 Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane" JAMg_model_20925.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" JAMg_model_2017.1 5 Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-1368108;Reactome: R-HSA-197264 "Neutrophil degranulation";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging" JAMg_model_15527.1 6 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-8939211;Reactome: R-HSA-5675221;Reactome: R-HSA-5693565 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"ESR-mediated signaling";"Negative regulation of MAPK pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" JAMg_model_3430.2 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" JAMg_model_19704.3 2 Reactome: R-HSA-2022928;MetaCyc: PWY-6558 "HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)" JAMg_model_20392.2 4 Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-110312 "Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Translesion synthesis by REV1" JAMg_model_7014.3 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_19917.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" JAMg_model_15154.6 1 KEGG: 00051+4.2.1.68 "Fructose and mannose metabolism" JAMg_model_14414.3 3 Reactome: R-HSA-1660662;Reactome: R-HSA-5626978;Reactome: R-HSA-193681 "Glycosphingolipid metabolism";"TNFR1-mediated ceramide production";"Ceramide signalling" JAMg_model_8803.2 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" JAMg_model_9054.6 3 MetaCyc: PWY-6117;KEGG: 00330+2.3.1.57;MetaCyc: PWY-0 "Spermine and spermidine degradation I";"Arginine and proline metabolism";"Putrescine degradation III" JAMg_model_19824.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" JAMg_model_11774.2 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" JAMg_model_15906.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_17785.2 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" JAMg_model_10767.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72706 "Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit" JAMg_model_16763.1 1 Reactome: R-HSA-211981 "Xenobiotics" JAMg_model_20651.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_6816.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" JAMg_model_20404.4 10 KEGG: 00562+5.3.1.1;KEGG: 00710+5.3.1.1;MetaCyc: PWY-1042;MetaCyc: PWY-5484;Reactome: R-HSA-70263;KEGG: 00010+5.3.1.1;Reactome: R-HSA-70171;MetaCyc: PWY-7003;KEGG: 00051+5.3.1.1;MetaCyc: PWY-6142 "Inositol phosphate metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycolysis";"Glycerol degradation to butanol";"Fructose and mannose metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" JAMg_model_13381.2 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" JAMg_model_14287.1 11 Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-174437;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-69166;Reactome: R-HSA-5693568 "Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate from the C-strand";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate";"Resolution of D-loop Structures through Holliday Junction Intermediates" JAMg_model_9072.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_1093.2 24 Reactome: R-HSA-9009391;Reactome: R-HSA-392851;Reactome: R-HSA-392170;Reactome: R-HSA-4086398;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-418217;Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-428930;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-400042;Reactome: R-HSA-416482;Reactome: R-HSA-418555;Reactome: R-HSA-500657;Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-392451;Reactome: R-HSA-8964315;Reactome: R-HSA-416476;Reactome: R-HSA-418597;Reactome: R-HSA-420092;Reactome: R-HSA-8964616 "Extra-nuclear estrogen signaling";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 12";"Ca2+ pathway";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PLC beta";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thromboxane signalling through TP receptor";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (12/13) signalling events";"G alpha (s) signalling events";"Presynaptic function of Kainate receptors";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through PI3Kgamma";"G beta:gamma signalling through BTK";"G alpha (q) signalling events";"G alpha (z) signalling events";"Glucagon-type ligand receptors";"G beta:gamma signalling through CDC42" JAMg_model_14813.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_9279.3 10 Reactome: R-HSA-72731;Reactome: R-HSA-156827;Reactome: R-HSA-9648895;Reactome: R-HSA-381042;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-382556;Reactome: R-HSA-72702 "Recycling of eIF2:GDP";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK1 (HRI) to heme deficiency";"PERK regulates gene expression";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ABC-family proteins mediated transport";"Ribosomal scanning and start codon recognition" JAMg_model_6601.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" JAMg_model_8578.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection" JAMg_model_15443.1 3 Reactome: R-HSA-373080;Reactome: R-HSA-4608870;Reactome: R-HSA-4086400 "Class B/2 (Secretin family receptors)";"Asymmetric localization of PCP proteins";"PCP/CE pathway" JAMg_model_8834.3 10 Reactome: R-HSA-75953;Reactome: R-HSA-73779;MetaCyc: PWY-7511;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167161 "RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Protein ubiquitination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation" JAMg_model_17419.7 12 Reactome: R-HSA-8854518;Reactome: R-HSA-6807878;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2132295;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-380284;Reactome: R-HSA-381038;Reactome: R-HSA-380270 "AURKA Activation by TPX2";"COPI-mediated anterograde transport";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"MHC class II antigen presentation";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of proteins required for interphase microtubule organization from the centrosome";"XBP1(S) activates chaperone genes";"Recruitment of mitotic centrosome proteins and complexes" JAMg_model_6327.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" JAMg_model_21252.4 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" JAMg_model_19670.3 5 Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-68867;Reactome: R-HSA-68827 "Orc1 removal from chromatin";"Activation of the pre-replicative complex";"G1/S-Specific Transcription";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex" JAMg_model_17458.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_13521.1 8 Reactome: R-HSA-442720;Reactome: R-HSA-164378;Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-180024 "CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Hedgehog 'off' state";"DARPP-32 events" JAMg_model_19569.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_18534.3 5 Reactome: R-HSA-1266695;Reactome: R-HSA-3214858;Reactome: R-HSA-201722;Reactome: R-HSA-3247509;Reactome: R-HSA-8939243 "Interleukin-7 signaling";"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" JAMg_model_5287.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" JAMg_model_20252.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" JAMg_model_21155.1 6 MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085;MetaCyc: PWY-5067;MetaCyc: PWY-622 "Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis" JAMg_model_7416.3 1 Reactome: R-HSA-2468052 "Establishment of Sister Chromatid Cohesion" JAMg_model_10124.4 6 KEGG: 00290+4.2.1.33;Reactome: R-HSA-71403;KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3;Reactome: R-HSA-1268020;KEGG: 00720+4.2.1.3 "Valine, leucine and isoleucine biosynthesis";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Mitochondrial protein import";"Carbon fixation pathways in prokaryotes" JAMg_model_7638.4 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_20117.3 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" JAMg_model_3318.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" JAMg_model_4282.2 4 Reactome: R-HSA-1614558;KEGG: 00270+1.13.11.20;MetaCyc: PWY-5331;KEGG: 00430+1.13.11.20 "Degradation of cysteine and homocysteine";"Cysteine and methionine metabolism";"Taurine biosynthesis I";"Taurine and hypotaurine metabolism" JAMg_model_9837.4 8 KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" JAMg_model_13314.1 5 MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109 "Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis" JAMg_model_9364.1 2 Reactome: R-HSA-8866652;Reactome: R-HSA-5357905 "Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of TNFR1 signaling" JAMg_model_3715.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_15299.1 4 Reactome: R-HSA-3000157;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" JAMg_model_6538.1 12 MetaCyc: PWY-5870;MetaCyc: PWY-5857;MetaCyc: PWY-5856;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5855;MetaCyc: PWY-5873;MetaCyc: PWY-6708;MetaCyc: PWY-5871;Reactome: R-HSA-1268020;MetaCyc: PWY-6978;MetaCyc: PWY-5872;Reactome: R-HSA-2142789 "Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Mitochondrial protein import";"Plastoquinol-9 biosynthesis II";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis" JAMg_model_8169.1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" JAMg_model_20230.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" JAMg_model_13891.1 2 KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788 "Starch and sucrose metabolism";"Cellulose degradation II (fungi)" JAMg_model_15492.2 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" JAMg_model_11562.4 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" JAMg_model_6678.3 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_8762.3 7 Reactome: R-HSA-201688;Reactome: R-HSA-4086400;Reactome: R-HSA-4641258;Reactome: R-HSA-5368598;Reactome: R-HSA-201681;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262 "WNT mediated activation of DVL";"PCP/CE pathway";"Degradation of DVL";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"TCF dependent signaling in response to WNT";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane" JAMg_model_17281.6 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_2037.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" JAMg_model_5193.1 4 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" JAMg_model_15154.8 1 KEGG: 00051+4.2.1.68 "Fructose and mannose metabolism" JAMg_model_2693.1 6 KEGG: 00670+2.1.2.5;Reactome: R-HSA-70921;KEGG: 00340+2.1.2.5;MetaCyc: PWY-5030;MetaCyc: PWY-5497;KEGG: 00670+4.3.1.4+2.1.2.5 "One carbon pool by folate";"Histidine catabolism";"Histidine metabolism";"L-histidine degradation III";"Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate" JAMg_model_6425.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" JAMg_model_6779.1 8 Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-6804115;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380270 "AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes" JAMg_model_20862.2 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" JAMg_model_15277.1 10 MetaCyc: PWY-1722;KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;MetaCyc: PWY-5497;MetaCyc: PWY-6613;MetaCyc: PWY-7909;MetaCyc: PWY-3841;Reactome: R-HSA-196757;MetaCyc: PWY-5030 "Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Folate transformations I";"Purine nucleobases degradation II (anaerobic)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"Metabolism of folate and pterines";"L-histidine degradation III" JAMg_model_2071.1 56 Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-5610785;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978 "AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)" JAMg_model_7648.2 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" JAMg_model_3605.1 12 Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878 "Mitotic Prometaphase";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Separation of Sister Chromatids";"COPI-mediated anterograde transport" JAMg_model_9243.1 1 Reactome: R-HSA-6785631 "ERBB2 Regulates Cell Motility" JAMg_model_6215.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" JAMg_model_17560.1 4 Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135 "Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Dual Incision in GG-NER";"Dual incision in TC-NER" JAMg_model_15816.1 5 Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-5545619;Reactome: R-HSA-201681;Reactome: R-HSA-8948751 "Degradation of AXIN";"Ub-specific processing proteases";"XAV939 inhibits tankyrase, stabilizing AXIN";"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity" JAMg_model_11543.1 6 Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68867 "Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex" JAMg_model_2414.1 4 Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257 "Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion" JAMg_model_4468.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" JAMg_model_18187.1 5 Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568 "Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates" JAMg_model_8553.3 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_13801.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" JAMg_model_20913.1 1 Reactome: R-HSA-163125 "Post-translational modification: synthesis of GPI-anchored proteins" JAMg_model_17287.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_10754.4 3 Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2 "VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway" JAMg_model_7691.3 2 MetaCyc: PWY-7511;Reactome: R-HSA-6783310 "Protein ubiquitination";"Fanconi Anemia Pathway" JAMg_model_11121.2 8 Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-113507 "CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation" JAMg_model_12693.3 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" JAMg_model_10263.2 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" JAMg_model_18582.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" JAMg_model_18595.1 5 Reactome: R-HSA-2426168;Reactome: R-HSA-75105;Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-9029558 "Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis";"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis" JAMg_model_9241.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" JAMg_model_16125.3 3 Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6784531 "tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the nucleus" JAMg_model_4738.2 1 Reactome: R-HSA-1221632 "Meiotic synapsis" JAMg_model_21260.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" JAMg_model_4541.8 7 Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284 "Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome" JAMg_model_580.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_11868.1 5 Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-3232118;Reactome: R-HSA-5693607 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"SUMOylation of transcription factors";"Processing of DNA double-strand break ends" JAMg_model_642.2 6 MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" JAMg_model_15364.2 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" JAMg_model_587.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" JAMg_model_13339.6 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" JAMg_model_19272.2 2 KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921 "Histidine metabolism";"Histidine catabolism" JAMg_model_12573.3 18 MetaCyc: PWY-6728;KEGG: 00620+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-5392;MetaCyc: PWY-8086;KEGG: 00630+1.1.1.37;MetaCyc: PWY-561;KEGG: 00020+1.1.1.37;MetaCyc: PWY-7383;Reactome: R-HSA-70263;KEGG: 00710+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-5913;KEGG: 00720+1.1.1.37;KEGG: 00270+1.1.1.37 "Methylaspartate cycle";"Pyruvate metabolism";"Methane metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reductive TCA cycle II";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Glyoxylate and dicarboxylate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation I (serine pathway)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Cysteine and methionine metabolism" JAMg_model_16456.4 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" JAMg_model_12221.2 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" JAMg_model_20172.1 9 MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;Reactome: R-HSA-112043;KEGG: 04070+3.1.4.11;Reactome: R-HSA-416476;MetaCyc: PWY-6351;MetaCyc: PWY-8052 "Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"PLC beta mediated events";"Phosphatidylinositol signaling system";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis" JAMg_model_19742.3 3 Reactome: R-HSA-1660661;Reactome: R-HSA-6798695;Reactome: R-HSA-9609523 "Sphingolipid de novo biosynthesis";"Neutrophil degranulation";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" JAMg_model_8700.2 8 Reactome: R-HSA-6798695;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897 "Neutrophil degranulation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"mTOR signalling";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes" JAMg_model_11403.2 6 Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176974 "Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Unwinding of DNA" JAMg_model_6042.4 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" JAMg_model_13392.1 13 Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-114508;Reactome: R-HSA-112043;Reactome: R-HSA-4086398;Reactome: R-HSA-5607763;Reactome: R-HSA-2871809;Reactome: R-HSA-5578775;Reactome: R-HSA-2029485;Reactome: R-HSA-422356;Reactome: R-HSA-381676;Reactome: R-HSA-5218921;Reactome: R-HSA-1489509 "Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Effects of PIP2 hydrolysis";"PLC beta mediated events";"Ca2+ pathway";"CLEC7A (Dectin-1) induces NFAT activation";"FCERI mediated Ca+2 mobilization";"Ion homeostasis";"Role of phospholipids in phagocytosis";"Regulation of insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"VEGFR2 mediated cell proliferation";"DAG and IP3 signaling" JAMg_model_17671.2 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" JAMg_model_3092.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68867 "Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex" JAMg_model_2466.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" JAMg_model_12329.1 14 MetaCyc: PWY-7254;KEGG: 00650+1.3.5.1;MetaCyc: PWY-6969;Reactome: R-HSA-611105;Reactome: R-HSA-71403;KEGG: 00190+1.3.5.1;MetaCyc: PWY-7279;MetaCyc: PWY-4302;MetaCyc: PWY-5690;MetaCyc: PWY-3781;KEGG: 00020+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6728;MetaCyc: PWY-561 "TCA cycle VII (acetate-producers)";"Butanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Respiratory electron transport";"Citric acid cycle (TCA cycle)";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle II (plants and fungi)";"Aerobic respiration I (cytochrome c)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation" JAMg_model_10093.3 1 Reactome: R-HSA-5620924 "Intraflagellar transport" JAMg_model_907.8 8 Reactome: R-HSA-190873;Reactome: R-HSA-432720;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-8856828 "Gap junction degradation";"Lysosome Vesicle Biogenesis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"Clathrin-mediated endocytosis" JAMg_model_5766.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_9881.5 5 KEGG: 00860+2.3.1.37;KEGG: 00260+2.3.1.37;MetaCyc: PWY-7536;Reactome: R-HSA-189451;MetaCyc: PWY-5189 "Porphyrin and chlorophyll metabolism";"Glycine, serine and threonine metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)" JAMg_model_8627.1 2 KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788 "Starch and sucrose metabolism";"Cellulose degradation II (fungi)" JAMg_model_9619.1 12 Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-1251985;Reactome: R-HSA-977225;Reactome: R-HSA-9017802;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-3928665;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700 "Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"Nuclear signaling by ERBB4";"Amyloid fiber formation";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus" JAMg_model_5017.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_9139.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" JAMg_model_5924.3 3 MetaCyc: PWY-7511;Reactome: R-HSA-349425;Reactome: R-HSA-8951664 "Protein ubiquitination";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation" JAMg_model_14694.1 5 Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300;Reactome: R-HSA-4655427;Reactome: R-HSA-427413 "DNA methylation";"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins";"NoRC negatively regulates rRNA expression" JAMg_model_15126.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Peptide chain elongation" JAMg_model_20773.2 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" JAMg_model_10357.2 5 Reactome: R-HSA-8856825;Reactome: R-HSA-432722;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440 "Cargo recognition for clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis";"Neutrophil degranulation";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network" JAMg_model_6476.3 4 Reactome: R-HSA-2408522;Reactome: R-HSA-379726;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.18 "Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" JAMg_model_15875.5 1 Reactome: R-HSA-8949613 "Cristae formation" JAMg_model_3078.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" JAMg_model_1639.2 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_3540.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" JAMg_model_7547.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" JAMg_model_9965.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" JAMg_model_17283.4 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_13532.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" JAMg_model_1507.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" JAMg_model_11556.1 15 Reactome: R-HSA-8936459;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX" JAMg_model_4930.1 6 Reactome: R-HSA-1268020;KEGG: 00190+7.1.2.2;Reactome: R-HSA-163210;KEGG: 00195+7.1.2.2;Reactome: R-HSA-8949613;MetaCyc: PWY-7980 "Mitochondrial protein import";"Oxidative phosphorylation";"Formation of ATP by chemiosmotic coupling";"Photosynthesis";"Cristae formation";"ATP biosynthesis" JAMg_model_3670.4 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" JAMg_model_10992.2 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" JAMg_model_10854.2 6 Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-6804756 "Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation" JAMg_model_18133.4 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_4926.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" JAMg_model_2312.3 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" JAMg_model_4378.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" JAMg_model_13305.1 1 Reactome: R-HSA-6798163 "Choline catabolism" JAMg_model_2106.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" JAMg_model_21349.1 1 Reactome: R-HSA-376172 "DSCAM interactions" JAMg_model_766.1 11 Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5358606;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5358565;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938 "HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)" JAMg_model_12049.2 52 Reactome: R-HSA-9018519;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-76061;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-5250924;Reactome: R-HSA-72203;Reactome: R-HSA-76042;Reactome: R-HSA-6803529;Reactome: R-HSA-5601884;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-6782135;Reactome: R-HSA-76071;Reactome: R-HSA-75953;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-76066;Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-5617472;Reactome: R-HSA-167172;Reactome: R-HSA-8851708;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-167238;Reactome: R-HSA-73863;Reactome: R-HSA-749476;Reactome: R-HSA-72163;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-167160;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-168325;Reactome: R-HSA-6781827;Reactome: R-HSA-6807505;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-203927;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-73780 "Estrogen-dependent gene expression";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"B-WICH complex positively regulates rRNA expression";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"FGFR2 alternative splicing";"PIWI-interacting RNA (piRNA) biogenesis";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"Dual incision in TC-NER";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcription of the HIV genome";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"mRNA Splicing - Major Pathway";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Viral Messenger RNA Synthesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"MicroRNA (miRNA) biogenesis";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Chain Elongation" JAMg_model_9043.3 9 Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472 "Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"RORA activates gene expression";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" JAMg_model_19474.1 3 Reactome: R-HSA-2206302;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101 "MPS I - Hurler syndrome";"HS-GAG degradation";"CS/DS degradation" JAMg_model_24.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" JAMg_model_15049.3 5 Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295 "COPII-mediated vesicle transport";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation" JAMg_model_14370.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_18413.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" JAMg_model_20738.6 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_1151.2 1 Reactome: R-HSA-8950505 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" JAMg_model_7461.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_11273.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" JAMg_model_9054.4 3 KEGG: 00330+2.3.1.57;MetaCyc: PWY-6117;MetaCyc: PWY-0 "Arginine and proline metabolism";"Spermine and spermidine degradation I";"Putrescine degradation III" JAMg_model_7235.1 6 Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange" JAMg_model_21258.3 8 Reactome: R-HSA-1222556;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;KEGG: 00195+7.1.2.2;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"ATP biosynthesis";"Oxidative phosphorylation";"Ion channel transport";"Amino acids regulate mTORC1";"Photosynthesis";"Transferrin endocytosis and recycling";"Insulin receptor recycling" JAMg_model_10657.2 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" JAMg_model_13700.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation" JAMg_model_9932.5 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_11724.1 13 MetaCyc: PWY-6370;KEGG: 00980+2.5.1.18;KEGG: 00982+2.5.1.18;Reactome: R-HSA-196836;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-4061;MetaCyc: PWY-7533;KEGG: 00983+2.5.1.18;MetaCyc: PWY-2261;KEGG: 00053+1.8.5.1;MetaCyc: PWY-7112;Reactome: R-HSA-156590;MetaCyc: PWY-6842 "Ascorbate recycling (cytosolic)";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"Vitamin C (ascorbate) metabolism";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Drug metabolism - other enzymes";"Ascorbate glutathione cycle";"Ascorbate and aldarate metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione conjugation";"Glutathione-mediated detoxification II" JAMg_model_4371.3 5 Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-6798695;Reactome: R-HSA-164843;Reactome: R-HSA-3270619 "Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"Neutrophil degranulation";"2-LTR circle formation";"IRF3-mediated induction of type I IFN" JAMg_model_3843.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214847 "NoRC negatively regulates rRNA expression";"HATs acetylate histones" JAMg_model_17161.4 5 MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-6317 "D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)" JAMg_model_6608.1 20 KEGG: 00020+2.3.3.8;MetaCyc: PWY-5392;Reactome: R-HSA-163765;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-5172;KEGG: 00720+2.3.3.8;Reactome: R-HSA-6798695;MetaCyc: PWY-6728;MetaCyc: PWY-5913;MetaCyc: PWY-6969;Reactome: R-HSA-1268020;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5537;Reactome: R-HSA-71403;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-7384;Reactome: R-HSA-75105 "Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"ChREBP activates metabolic gene expression";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"Acetyl-coa biosynthesis III (from citrate)";"Carbon fixation pathways in prokaryotes";"Neutrophil degranulation";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Mitochondrial protein import";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Fatty acyl-CoA biosynthesis" JAMg_model_13274.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" JAMg_model_1571.3 3 Reactome: R-HSA-390471;Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Association of TriC/CCT with target proteins during biosynthesis";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_13540.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" JAMg_model_18147.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" JAMg_model_5119.2 11 Reactome: R-HSA-69017;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-1362277 "CDK-mediated phosphorylation and removal of Cdc6";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex" JAMg_model_16196.1 2 Reactome: R-HSA-74259;KEGG: 00230+3.6.1.66 "Purine catabolism";"Purine metabolism" JAMg_model_5615.1 9 Reactome: R-HSA-193648;Reactome: R-HSA-2871796;Reactome: R-HSA-194840;Reactome: R-HSA-114604;Reactome: R-HSA-5218920;Reactome: R-HSA-2871809;Reactome: R-HSA-4420097;Reactome: R-HSA-416482;Reactome: R-HSA-2029482 "NRAGE signals death through JNK";"FCERI mediated MAPK activation";"Rho GTPase cycle";"GPVI-mediated activation cascade";"VEGFR2 mediated vascular permeability";"FCERI mediated Ca+2 mobilization";"VEGFA-VEGFR2 Pathway";"G alpha (12/13) signalling events";"Regulation of actin dynamics for phagocytic cup formation" JAMg_model_6073.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" JAMg_model_13773.1 7 Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-9610379;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-917729 "Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"HCMV Late Events";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"Endosomal Sorting Complex Required For Transport (ESCRT)" JAMg_model_3129.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" JAMg_model_7256.3 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" JAMg_model_11816.3 1 Reactome: R-HSA-70635 "Urea cycle" JAMg_model_20604.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" JAMg_model_7189.4 12 KEGG: 05170+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;Reactome: R-HSA-418885;Reactome: R-HSA-193648;Reactome: R-HSA-416476;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"DCC mediated attractive signaling";"NRAGE signals death through JNK";"G alpha (q) signalling events";"Relaxin signaling pathway";"Human papillomavirus infection";"Rho GTPase cycle";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway" JAMg_model_4987.2 29 Reactome: R-HSA-5358606;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-174437;Reactome: R-HSA-68962;Reactome: R-HSA-5696397;Reactome: R-HSA-5358565;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-176187;Reactome: R-HSA-69166;Reactome: R-HSA-6782210;Reactome: R-HSA-3371511;Reactome: R-HSA-3108214;Reactome: R-HSA-912446;Reactome: R-HSA-3371453;Reactome: R-HSA-5685938;Reactome: R-HSA-5696395;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121;Reactome: R-HSA-110314;Reactome: R-HSA-6804756;Reactome: R-HSA-5655862;Reactome: R-HSA-6783310;Reactome: R-HSA-6782135;Reactome: R-HSA-110312;Reactome: R-HSA-5696400 "Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate from the C-strand";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Activation of ATR in response to replication stress";"Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HSF1 activation";"SUMOylation of DNA damage response and repair proteins";"Meiotic recombination";"Regulation of HSF1-mediated heat shock response";"HDR through Single Strand Annealing (SSA)";"Formation of Incision Complex in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLK";"Fanconi Anemia Pathway";"Dual incision in TC-NER";"Translesion synthesis by REV1";"Dual Incision in GG-NER" JAMg_model_12281.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-983231 "Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production" JAMg_model_4971.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" JAMg_model_8589.2 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942 "Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition" JAMg_model_1730.3 3 KEGG: 00970+6.1.1.4;Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" JAMg_model_16498.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" JAMg_model_238.3 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" JAMg_model_10213.2 8 Reactome: R-HSA-163754;Reactome: R-HSA-6791462;MetaCyc: PWY-1861;Reactome: R-HSA-6791055;KEGG: 00030+2.2.1.2;Reactome: R-HSA-71336;MetaCyc: PWY-5723;Reactome: R-HSA-8950505 "Insulin effects increased synthesis of Xylulose-5-Phosphate";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Pentose phosphate pathway";"Pentose phosphate pathway";"Rubisco shunt";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" JAMg_model_5966.1 3 Reactome: R-HSA-70350;KEGG: 00051+2.7.1.3;Reactome: R-HSA-5657562 "Fructose catabolism";"Fructose and mannose metabolism";"Essential fructosuria" JAMg_model_21315.1 15 KEGG: 00620+2.7.1.40;MetaCyc: PWY-6142;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-6886;MetaCyc: PWY-8004;MetaCyc: PWY-2221;MetaCyc: PWY-5723;KEGG: 00230+2.7.1.40;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-7383;MetaCyc: PWY-7218 "Pyruvate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Glycerol degradation to butanol";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Rubisco shunt";"Purine metabolism";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)" JAMg_model_19648.3 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" JAMg_model_9315.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" JAMg_model_9186.6 6 KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039 "Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule" JAMg_model_10273.1 31 MetaCyc: PWY-8012;MetaCyc: PWY-6519;Reactome: R-HSA-2426168;MetaCyc: PWY-6799;MetaCyc: PWY-6282;MetaCyc: PWY-6113;MetaCyc: PWY-4381;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5973;Reactome: R-HSA-75105;MetaCyc: PWY-5966-1;MetaCyc: PWY-7664;Reactome: R-HSA-9029558;MetaCyc: PWY-5989;MetaCyc: PWY-5147;Reactome: R-HSA-163765;MetaCyc: PWY-5142;MetaCyc: PWY-8047;MetaCyc: PWY-8049;MetaCyc: PWY-7858;MetaCyc: PWY-5971;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7388;MetaCyc: PWY-5366;MetaCyc: PWY-7663;MetaCyc: PWY-7723;Reactome: R-HSA-199220;MetaCyc: PWY-5994;MetaCyc: PWY-5367;MetaCyc: PWY-7746;MetaCyc: PWYG-321 "Mupirocin biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Superpathway of mycolate biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Biotin metabolism";"Cis-vaccenate biosynthesis";"Fatty acyl-CoA biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Oleate biosynthesis IV (anaerobic)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Stearate biosynthesis II (bacteria and plants)";"Oleate biosynthesis I (plants)";"ChREBP activates metabolic gene expression";"Acyl-[acyl-carrier protein] thioesterase pathway";"Bryostatin biosynthesis";"Pederin biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitoleate biosynthesis II (plants and bacteria)";"Gondoate biosynthesis (anaerobic)";"Bacterial bioluminescence";"Vitamin B5 (pantothenate) metabolism";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Petroselinate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"" JAMg_model_15739.1 6 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556 "Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Neutrophil degranulation";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes" JAMg_model_9186.2 6 MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism" JAMg_model_2359.1 30 KEGG: 05163+2.7.11.1;Reactome: R-HSA-1358803;Reactome: R-HSA-211163;Reactome: R-HSA-5628897;Reactome: R-HSA-6804758;KEGG: 05170+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-199418;Reactome: R-HSA-198693;Reactome: R-HSA-111447;Reactome: R-HSA-9634638;Reactome: R-HSA-8941332;Reactome: R-HSA-5218920;Reactome: R-HSA-392451;Reactome: R-HSA-5674400;Reactome: R-HSA-69656;Reactome: R-HSA-6804757;KEGG: 04714+2.7.11.1;Reactome: R-HSA-8948751;Reactome: R-HSA-198323;Reactome: R-HSA-69202;Reactome: R-HSA-1257604;Reactome: R-HSA-9614399;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804759;KEGG: 04151+2.7.11.1;Reactome: R-HSA-389513;KEGG: 04926+2.7.11.1;Reactome: R-HSA-8876198;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"Downregulation of ERBB2:ERBB3 signaling";"AKT-mediated inactivation of FOXO1A";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Activity through Acetylation";"Human immunodeficiency virus 1 infection";"CD28 dependent PI3K/Akt signaling";"Negative regulation of the PI3K/AKT network";"AKT phosphorylates targets in the nucleus";"Activation of BAD and translocation to mitochondria";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RUNX2 regulates genes involved in cell migration";"VEGFR2 mediated vascular permeability";"G beta:gamma signalling through PI3Kgamma";"Constitutive Signaling by AKT1 E17K in Cancer";"Cyclin A:Cdk2-associated events at S phase entry";"Regulation of TP53 Degradation";"Thermogenesis";"Regulation of PTEN stability and activity";"AKT phosphorylates targets in the cytosol";"Cyclin E associated events during G1/S transition";"PIP3 activates AKT signaling";"Regulation of localization of FOXO transcription factors";"mTOR signaling pathway";"Regulation of TP53 Activity through Association with Co-factors";"PI3K-Akt signaling pathway";"CTLA4 inhibitory signaling";"Relaxin signaling pathway";"RAB GEFs exchange GTP for GDP on RABs";"Human papillomavirus infection" JAMg_model_15023.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" JAMg_model_8400.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_16534.1 3 Reactome: R-HSA-381038;Reactome: R-HSA-381426;Reactome: R-HSA-8957275 "XBP1(S) activates chaperone genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation" JAMg_model_18325.7 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" JAMg_model_7862.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_4776.1 2 Reactome: R-HSA-8876725;Reactome: R-HSA-3371453 "Protein methylation";"Regulation of HSF1-mediated heat shock response" JAMg_model_5373.1 3 Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" JAMg_model_872.2 4 MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1;Reactome: R-HSA-71737;MetaCyc: PWY-7807 "(aminomethyl)phosphonate degradation";"Oxidative phosphorylation";"Pyrophosphate hydrolysis";"Glyphosate degradation III" JAMg_model_16589.6 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" JAMg_model_14022.1 1 Reactome: R-HSA-375276 "Peptide ligand-binding receptors" JAMg_model_15573.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" JAMg_model_7606.1 20 Reactome: R-HSA-5696397;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-6782210;Reactome: R-HSA-176187;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-6804756;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121 "Gap-filling DNA repair synthesis and ligation in GG-NER";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of ATR in response to replication stress";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"Polymerase switching";"Dual incision in TC-NER";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of TP53 Activity through Phosphorylation";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI" JAMg_model_1940.1 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" JAMg_model_18438.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_16805.1 7 Reactome: R-HSA-9020265;Reactome: R-HSA-9018681;Reactome: R-HSA-6798695;Reactome: R-HSA-2142691;Reactome: R-HSA-9023661;Reactome: R-HSA-9018676;Reactome: R-HSA-9018896 "Biosynthesis of aspirin-triggered D-series resolvins";"Biosynthesis of protectins";"Neutrophil degranulation";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Biosynthesis of E-series 18(R)-resolvins";"Biosynthesis of D-series resolvins";"Biosynthesis of E-series 18(S)-resolvins" JAMg_model_8560.4 24 Reactome: R-HSA-9648025;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497 "EML4 and NUDC in mitotic spindle formation";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"HCMV Early Events";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" JAMg_model_1274.2 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" JAMg_model_18134.1 5 MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-7269 "NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" JAMg_model_6846.1 7 KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-6824 "Phenylpropanoid biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis" JAMg_model_18918.5 3 Reactome: R-HSA-70268;MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5 "Pyruvate metabolism";"Methylglyoxal degradation I";"Pyruvate metabolism" JAMg_model_10881.1 4 Reactome: R-HSA-8934903;Reactome: R-HSA-936440;Reactome: R-HSA-5205685;Reactome: R-HSA-1632852 "Receptor Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy";"Macroautophagy" JAMg_model_6807.1 5 KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3;KEGG: 00720+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00630+4.2.1.3 "Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Iron uptake and transport";"Glyoxylate and dicarboxylate metabolism" JAMg_model_16740.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" JAMg_model_907.9 8 Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-3928665;Reactome: R-HSA-432720;Reactome: R-HSA-190873;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"EPH-ephrin mediated repulsion of cells";"Lysosome Vesicle Biogenesis";"Gap junction degradation";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" JAMg_model_8904.1 12 Reactome: R-HSA-193692;Reactome: R-HSA-1251985;Reactome: R-HSA-2660826;Reactome: R-HSA-1442490;Reactome: R-HSA-177929;Reactome: R-HSA-2644606;Reactome: R-HSA-5362798;Reactome: R-HSA-982772;Reactome: R-HSA-75893;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862 "Regulated proteolysis of p75NTR";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Collagen degradation";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Release of Hh-Np from the secreting cell";"Growth hormone receptor signaling";"TNF signaling";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" JAMg_model_671.1 6 Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5685938 "Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)" JAMg_model_9889.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" JAMg_model_16106.1 10 KEGG: 00710+2.7.2.3;MetaCyc: PWY-7003;Reactome: R-HSA-70171;KEGG: 00010+2.7.2.3;MetaCyc: PWY-6901;MetaCyc: PWY-1042;MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-6886;MetaCyc: PWY-8004 "Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Glycolysis";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I" JAMg_model_18100.6 1 Reactome: R-HSA-1632852 "Macroautophagy" JAMg_model_20891.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" JAMg_model_8031.3 3 KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581;MetaCyc: PWY-6823 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" JAMg_model_9516.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" JAMg_model_18440.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" JAMg_model_11882.2 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" JAMg_model_7975.2 6 Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;MetaCyc: PWY-6854;Reactome: R-HSA-8862803;Reactome: R-HSA-8950505;Reactome: R-HSA-2151201 "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Transcriptional activation of mitochondrial biogenesis" JAMg_model_16685.1 1 Reactome: R-HSA-1632852 "Macroautophagy" JAMg_model_19399.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_11795.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_7998.5 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" JAMg_model_14502.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_14760.3 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" JAMg_model_14838.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_562.1 19 Reactome: R-HSA-8957275;Reactome: R-HSA-3000480;Reactome: R-HSA-8964038;Reactome: R-HSA-5686938;Reactome: R-HSA-202733;Reactome: R-HSA-3000471;Reactome: R-HSA-8856825;Reactome: R-HSA-3000484;Reactome: R-HSA-8856828;Reactome: R-HSA-8964026;Reactome: R-HSA-8964041;Reactome: R-HSA-8964046;Reactome: R-HSA-8963901;Reactome: R-HSA-3000497;Reactome: R-HSA-432142;Reactome: R-HSA-381426;Reactome: R-HSA-975634;Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "Post-translational protein phosphorylation";"Scavenging by Class A Receptors";"LDL clearance";"Regulation of TLR by endogenous ligand";"Cell surface interactions at the vascular wall";"Scavenging by Class B Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class F Receptors";"Clathrin-mediated endocytosis";"Chylomicron clearance";"LDL remodeling";"VLDL clearance";"Chylomicron remodeling";"Scavenging by Class H Receptors";"Platelet sensitization by LDL";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Retinoid metabolism and transport";"VLDL assembly";"Chylomicron assembly" JAMg_model_5401.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" JAMg_model_1335.3 7 Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;MetaCyc: PWY-7511;Reactome: R-HSA-2122948 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Protein ubiquitination";"Activated NOTCH1 Transmits Signal to the Nucleus" JAMg_model_12710.1 6 KEGG: 00730+2.7.6.2;MetaCyc: PWY-7356;MetaCyc: PWY-6908;MetaCyc: PWY-6907;MetaCyc: PWY-6898;Reactome: R-HSA-196819 "Thiamine metabolism";"Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage III";"Vitamin B1 (thiamin) metabolism" JAMg_model_471.1 4 Reactome: R-HSA-70921;KEGG: 00340+2.1.2.5;MetaCyc: PWY-5030;KEGG: 00670+2.1.2.5 "Histidine catabolism";"Histidine metabolism";"L-histidine degradation III";"One carbon pool by folate" JAMg_model_9184.2 6 Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817 "Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)" JAMg_model_8826.3 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" JAMg_model_11905.2 25 Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-380270;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-9648025;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-68877 "RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"EML4 and NUDC in mitotic spindle formation";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"HCMV Early Events";"Mitotic Prometaphase" JAMg_model_6410.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_4292.1 4 Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-445095 "RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins" JAMg_model_18194.3 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" JAMg_model_15470.2 57 Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-195253 "GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"UCH proteinases";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex" JAMg_model_3644.1 7 KEGG: 00230+2.4.2.7;Reactome: R-HSA-74217;MetaCyc: PWY-7805;MetaCyc: PWY-6610;MetaCyc: PWY-7807;MetaCyc: PWY-6605;Reactome: R-HSA-6798695 "Purine metabolism";"Purine salvage";"(aminomethyl)phosphonate degradation";"Adenine salvage";"Glyphosate degradation III";"Adenine and adenosine salvage II";"Neutrophil degranulation" JAMg_model_13781.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" JAMg_model_6691.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733 "Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis" JAMg_model_9370.1 6 Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554 "Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" JAMg_model_7108.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_14120.2 11 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-450302;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-171007;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-4420097;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"activated TAK1 mediates p38 MAPK activation";"Thermogenesis";"Relaxin signaling pathway";"p38MAPK events";"Human cytomegalovirus infection";"Oxidative Stress Induced Senescence";"VEGFA-VEGFR2 Pathway";"Human immunodeficiency virus 1 infection" JAMg_model_12174.3 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" JAMg_model_4474.2 6 MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23 "Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Other glycan degradation";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series" JAMg_model_669.1 4 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism";"Cytosolic tRNA aminoacylation" JAMg_model_3792.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" JAMg_model_5588.5 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" JAMg_model_11904.3 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" JAMg_model_14275.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-163560;Reactome: R-HSA-5663220;KEGG: 05235+3.1.3.16;Reactome: R-HSA-68877;KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-2467813;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2500257;Reactome: R-HSA-2173788;Reactome: R-HSA-9648025 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Triglyceride catabolism";"RHO GTPases Activate Formins";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Mitotic Prometaphase";"Th1 and Th2 cell differentiation";"Circadian Clock";"Separation of Sister Chromatids";"T cell receptor signaling pathway";"Resolution of Sister Chromatid Cohesion";"Downregulation of TGF-beta receptor signaling";"EML4 and NUDC in mitotic spindle formation" JAMg_model_10683.3 1 Reactome: R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" JAMg_model_1523.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8949613 "Mitochondrial protein import";"Cristae formation" JAMg_model_12368.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" JAMg_model_7495.1 1 Reactome: R-HSA-191859 "snRNP Assembly" JAMg_model_8077.2 5 Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554 "HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" JAMg_model_14591.1 22 Reactome: R-HSA-389513;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-5673000;Reactome: R-HSA-141444;Reactome: R-HSA-6811558;Reactome: R-HSA-195253;Reactome: R-HSA-5663220;Reactome: R-HSA-432142;Reactome: R-HSA-5339716;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025;Reactome: R-HSA-5467337;Reactome: R-HSA-5675221;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-5358752;Reactome: R-HSA-68877 "CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"RAF activation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Degradation of beta-catenin by the destruction complex";"RHO GTPases Activate Formins";"Platelet sensitization by LDL";"Misspliced GSK3beta mutants stabilize beta-catenin";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding";"Negative regulation of MAPK pathway";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase" JAMg_model_20377.1 1 Reactome: R-HSA-72731 "Recycling of eIF2:GDP" JAMg_model_7002.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" JAMg_model_990.3 14 KEGG: 00670+2.1.2.1;MetaCyc: PWY-5497;MetaCyc: PWY-1622;MetaCyc: PWY-2201;KEGG: 00260+2.1.2.1;MetaCyc: PWY-2161;MetaCyc: PWY-181;MetaCyc: PWY-3661;MetaCyc: PWY-3661-1;Reactome: R-HSA-196757;MetaCyc: PWY-3841;KEGG: 00460+2.1.2.1;KEGG: 00630+2.1.2.1;KEGG: 00680+2.1.2.1 "One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Formaldehyde assimilation I (serine pathway)";"Folate transformations I";"Glycine, serine and threonine metabolism";"Folate polyglutamylation";"Photorespiration ";"Glycine betaine degradation I";"Glycine betaine degradation II (mammalian)";"Metabolism of folate and pterines";"Folate transformations II (plants)";"Cyanoamino acid metabolism";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism" JAMg_model_9781.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_10740.1 1 Reactome: R-HSA-6798163 "Choline catabolism" JAMg_model_9707.2 4 Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-400511 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)" JAMg_model_3582.1 57 Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091 "Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"UCH proteinases";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells" JAMg_model_866.1 2 Reactome: R-HSA-8853659;Reactome: R-HSA-5673001 "RET signaling";"RAF/MAP kinase cascade" JAMg_model_11895.4 5 MetaCyc: PWY-5531;KEGG: 00860+4.1.1.37;MetaCyc: PWY-7766;Reactome: R-HSA-189451;MetaCyc: PWY-7159 "3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Porphyrin and chlorophyll metabolism";"Heme b biosynthesis IV (Gram-positive bacteria)";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)" JAMg_model_15403.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-3214847 "Ub-specific processing proteases";"HATs acetylate histones" JAMg_model_15494.3 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" JAMg_model_13434.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" JAMg_model_17000.2 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" JAMg_model_9797.6 1 Reactome: R-HSA-191273 "Cholesterol biosynthesis" JAMg_model_20787.11 32 Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167160;Reactome: R-HSA-72163;Reactome: R-HSA-6807505;Reactome: R-HSA-168325;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-72203;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-6803529;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-73776 "mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes";"Viral Messenger RNA Synthesis";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Promoter Escape" JAMg_model_2167.1 13 Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320;Reactome: R-HSA-3000171;Reactome: R-HSA-2243919;Reactome: R-HSA-186797;Reactome: R-HSA-3000157;Reactome: R-HSA-1474244;Reactome: R-HSA-3000178;Reactome: R-HSA-216083;Reactome: R-HSA-1442490;Reactome: R-HSA-419037 "Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation";"Non-integrin membrane-ECM interactions";"Crosslinking of collagen fibrils";"Signaling by PDGF";"Laminin interactions";"Extracellular matrix organization";"ECM proteoglycans";"Integrin cell surface interactions";"Collagen degradation";"NCAM1 interactions" JAMg_model_514.1 8 Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-6798695;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380270 "AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Neutrophil degranulation";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes" JAMg_model_15969.1 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_18967.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" JAMg_model_14540.2 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" JAMg_model_5321.1 1 Reactome: R-HSA-211981 "Xenobiotics" JAMg_model_9207.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" JAMg_model_2586.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_17281.5 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_9948.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" JAMg_model_6030.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-1632852 "Ub-specific processing proteases";"Macroautophagy" JAMg_model_2207.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606 "HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" JAMg_model_13843.2 5 MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22 "Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Glycerolipid metabolism";"Sphingolipid metabolism" JAMg_model_13316.3 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_6885.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" JAMg_model_17785.4 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" JAMg_model_13501.2 6 Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706 "Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit" JAMg_model_18910.3 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" JAMg_model_5567.1 1 Reactome: R-HSA-1632852 "Macroautophagy" JAMg_model_10881.3 4 Reactome: R-HSA-1632852;Reactome: R-HSA-5205685;Reactome: R-HSA-936440;Reactome: R-HSA-8934903 "Macroautophagy";"Pink/Parkin Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy" JAMg_model_2073.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" JAMg_model_17608.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_11385.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" JAMg_model_12652.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" JAMg_model_6691.2 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis" JAMg_model_308.3 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1660661 "Neutrophil degranulation";"Sphingolipid de novo biosynthesis" JAMg_model_8393.3 2 Reactome: R-HSA-2408508;Reactome: R-HSA-389661 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation" JAMg_model_20400.1 6 Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6798695 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Neutrophil degranulation" JAMg_model_7997.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" JAMg_model_7190.3 12 KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-193648;KEGG: 04926+2.7.11.1;Reactome: R-HSA-418885;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Rho GTPase cycle";"Human papillomavirus infection";"G alpha (q) signalling events";"NRAGE signals death through JNK";"Relaxin signaling pathway";"DCC mediated attractive signaling";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"Human immunodeficiency virus 1 infection" JAMg_model_5588.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" JAMg_model_19131.4 14 KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483213;MetaCyc: PWY-8051;KEGG: 00565+3.1.3.4;Reactome: R-HSA-75109;Reactome: R-HSA-4419969;KEGG: 00600+3.1.3.4;Reactome: R-HSA-1483191;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-8052;MetaCyc: PWY-6453;MetaCyc: PWY-8055;KEGG: 00564+3.1.3.4 "Glycerolipid metabolism";"Synthesis of PE";"Anandamide biosynthesis I";"Ether lipid metabolism";"Triglyceride biosynthesis";"Depolymerisation of the Nuclear Lamina";"Sphingolipid metabolism";"Synthesis of PC";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"2-arachidonoylglycerol biosynthesis";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism" JAMg_model_885.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" JAMg_model_5169.1 1 Reactome: R-HSA-211981 "Xenobiotics" JAMg_model_2344.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" JAMg_model_2408.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_18798.1 1 Reactome: R-HSA-5627083 "RHO GTPases regulate CFTR trafficking" JAMg_model_2993.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" JAMg_model_9544.2 1 Reactome: R-HSA-6804760 "Regulation of TP53 Activity through Methylation" JAMg_model_18048.1 5 KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;MetaCyc: PWY-5514;Reactome: R-HSA-70171;MetaCyc: PWY-6906 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis";"Chitin derivatives degradation" JAMg_model_13191.1 9 Reactome: R-HSA-416476;MetaCyc: PWY-6351;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;Reactome: R-HSA-112043 "G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"PLC beta mediated events" JAMg_model_7411.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691 "Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" JAMg_model_2713.1 6 Reactome: R-HSA-196807;KEGG: 00760+6.3.1.5;MetaCyc: PWY-7761;MetaCyc: PWY-5653;MetaCyc: PWY-5381;KEGG: 00760+6.3.5.1 "Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism" JAMg_model_4151.2 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" JAMg_model_10754.1 3 Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097 "Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway" JAMg_model_12573.4 18 MetaCyc: PWY-5392;KEGG: 00630+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-7115;KEGG: 00620+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-6728;KEGG: 00720+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-5913;KEGG: 00710+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-5690;Reactome: R-HSA-70263;MetaCyc: PWY-7383;KEGG: 00020+1.1.1.37;MetaCyc: PWY-561 "Reductive TCA cycle II";"Glyoxylate and dicarboxylate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Pyruvate metabolism";"Methane metabolism";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Cysteine and methionine metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation I (serine pathway)";"TCA cycle II (plants and fungi)";"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation" JAMg_model_2503.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" JAMg_model_4117.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_2017.3 5 Reactome: R-HSA-1368108;MetaCyc: PWY-5381;Reactome: R-HSA-197264;Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21 "BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism" JAMg_model_15933.2 1 KEGG: 00270+2.1.1.37 "Cysteine and methionine metabolism" JAMg_model_194.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Viral mRNA Translation" JAMg_model_8547.3 5 Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-430039 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease" JAMg_model_15870.5 8 KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1 "Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis";"Starch and sucrose metabolism" JAMg_model_6411.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" JAMg_model_1583.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_9948.5 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" JAMg_model_13905.1 27 Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-168276;Reactome: R-HSA-170822 "HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein" JAMg_model_1124.4 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" JAMg_model_235.1 5 Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-6344;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2 "Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism" JAMg_model_15419.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9610379 "Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"HCMV Late Events" JAMg_model_13388.2 7 Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-749476 "Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" JAMg_model_7593.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" JAMg_model_1554.2 8 Reactome: R-HSA-8953750;Reactome: R-HSA-111459;Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-111464;Reactome: R-HSA-6803207;Reactome: R-HSA-6798695 "Transcriptional Regulation by E2F6";"Activation of caspases through apoptosome-mediated cleavage";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Neutrophil degranulation" JAMg_model_6229.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" JAMg_model_8468.1 3 Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691 "Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" JAMg_model_13671.7 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" JAMg_model_10427.2 3 Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Ub-specific processing proteases" JAMg_model_3039.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_6292.2 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" JAMg_model_17106.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" JAMg_model_16703.2 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" JAMg_model_14820.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_602.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72764 "L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination" JAMg_model_6993.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" JAMg_model_5433.5 4 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling" JAMg_model_9215.1 12 MetaCyc: PWY-5872;Reactome: R-HSA-2142789;MetaCyc: PWY-7230;MetaCyc: PWY-6708;MetaCyc: PWY-5873;MetaCyc: PWY-5855;MetaCyc: PWY-5871;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5856;MetaCyc: PWY-5857;MetaCyc: PWY-7233;MetaCyc: PWY-5870 "Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)" JAMg_model_17664.4 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" JAMg_model_4871.1 4 KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)" JAMg_model_3038.1 4 Reactome: R-HSA-8866427;Reactome: R-HSA-9031525;Reactome: R-HSA-983168;MetaCyc: PWY-7511 "VLDLR internalisation and degradation";"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" JAMg_model_8298.9 4 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-1912420 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi" JAMg_model_15494.2 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" JAMg_model_947.3 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" JAMg_model_18865.4 6 KEGG: 00260+2.6.1.52;KEGG: 00680+2.6.1.52;MetaCyc: PWY-8010;KEGG: 00270+2.6.1.52;KEGG: 00750+2.6.1.52;Reactome: R-HSA-977347 "Glycine, serine and threonine metabolism";"Methane metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Cysteine and methionine metabolism";"Vitamin B6 metabolism";"Serine biosynthesis" JAMg_model_2842.2 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_4861.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" JAMg_model_17834.2 3 MetaCyc: PWY-6689;Reactome: R-HSA-6784531;MetaCyc: PWY-7803 "Trna splicing I";"tRNA processing in the nucleus";"Trna splicing II" JAMg_model_18184.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" JAMg_model_16428.2 4 KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051 "Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I" JAMg_model_3669.3 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" JAMg_model_2187.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_957.9 4 Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases activate KTN1";"Kinesins" JAMg_model_5804.1 2 KEGG: 00290+4.3.1.19;KEGG: 00260+4.3.1.19 "Valine, leucine and isoleucine biosynthesis";"Glycine, serine and threonine metabolism" JAMg_model_19513.2 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" JAMg_model_13860.1 7 KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis" JAMg_model_16444.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_10201.3 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_4541.3 7 Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320 "AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes" JAMg_model_12772.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" JAMg_model_11645.4 5 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288 "Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1" JAMg_model_18440.2 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" JAMg_model_13531.1 14 MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7619 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis" JAMg_model_11570.1 5 Reactome: R-HSA-5693565;Reactome: R-HSA-5689901;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5693607 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Metalloprotease DUBs";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends" JAMg_model_10419.1 1 Reactome: R-HSA-6798163 "Choline catabolism" JAMg_model_14414.1 3 Reactome: R-HSA-193681;Reactome: R-HSA-1660662;Reactome: R-HSA-5626978 "Ceramide signalling";"Glycosphingolipid metabolism";"TNFR1-mediated ceramide production" JAMg_model_4350.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" JAMg_model_20513.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" JAMg_model_20917.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" JAMg_model_8159.6 12 MetaCyc: PWY-1861;MetaCyc: PWY-6142;Reactome: R-HSA-70171;KEGG: 00030+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00051+4.1.2.13;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00680+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-5484 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)" JAMg_model_11800.1 13 MetaCyc: PWY-6859;MetaCyc: PWY-7102;MetaCyc: PWY-5122;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7182;MetaCyc: PWY-7709;MetaCyc: PWY-7721;MetaCyc: PWY-6383;MetaCyc: PWY-7410;MetaCyc: PWY-7141;MetaCyc: PWY-5123;MetaCyc: PWY-7659;MetaCyc: PWY-7736 "All-trans-farnesol biosynthesis";"Bisabolene biosynthesis (engineered)";"Geranyl diphosphate biosynthesis";"Terpenoid backbone biosynthesis";"Linalool biosynthesis I";"(3R)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Ipsdienol biosynthesis";"(3S)-linalool biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Viridicatumtoxin biosynthesis";"Stellatic acid biosynthesis" JAMg_model_15621.3 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" JAMg_model_19735.2 14 KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;Reactome: R-HSA-975634;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-6803;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7409 "Linoleic acid metabolism";"Anandamide biosynthesis II";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Retinoid metabolism and transport";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)" JAMg_model_18015.3 5 Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-3214815;Reactome: R-HSA-2644606;Reactome: R-HSA-350054 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway" JAMg_model_20930.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" JAMg_model_1396.1 1 Reactome: R-HSA-6798163 "Choline catabolism" JAMg_model_17489.3 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" JAMg_model_2463.2 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" JAMg_model_11590.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823 "Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex" JAMg_model_10060.1 2 KEGG: 00260+2.3.1.29;Reactome: R-HSA-8849175 "Glycine, serine and threonine metabolism";"Threonine catabolism" JAMg_model_11142.1 4 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)" JAMg_model_6449.1 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_18891.3 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" JAMg_model_9895.9 10 MetaCyc: PWY-7328;KEGG: 00520+5.1.3.2;Reactome: R-HSA-5609977;MetaCyc: PWY-6397;Reactome: R-HSA-70370;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-3821;MetaCyc: PWY-6317;MetaCyc: PWY-7344 "Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose catabolism";"Galactose metabolism";"Stachyose degradation";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"UDP-alpha-D-galactose biosynthesis" JAMg_model_11172.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" JAMg_model_938.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" JAMg_model_395.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" JAMg_model_397.1 43 Reactome: R-HSA-427389;Reactome: R-HSA-2559582;Reactome: R-HSA-3214815;Reactome: R-HSA-432722;Reactome: R-HSA-5617472;Reactome: R-HSA-8939236;Reactome: R-HSA-3214841;Reactome: R-HSA-171306;Reactome: R-HSA-8936459;Reactome: R-HSA-606279;Reactome: R-HSA-1912408;Reactome: R-HSA-9610379;Reactome: R-HSA-427413;Reactome: R-HSA-2559586;Reactome: R-HSA-5578749;Reactome: R-HSA-2559580;Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-1221632;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-73728;Reactome: R-HSA-3214842;Reactome: R-HSA-5693607;Reactome: R-HSA-9018519;Reactome: R-HSA-4551638;Reactome: R-HSA-2299718;Reactome: R-HSA-201722;Reactome: R-HSA-110329;Reactome: R-HSA-5250924;Reactome: R-HSA-427359;Reactome: R-HSA-69473;Reactome: R-HSA-212300;Reactome: R-HSA-110328;Reactome: R-HSA-5625886;Reactome: R-HSA-5693565;Reactome: R-HSA-73772;Reactome: R-HSA-977225;Reactome: R-HSA-5334118;Reactome: R-HSA-9609690;Reactome: R-HSA-3214847;Reactome: R-HSA-9616222;Reactome: R-HSA-3214858 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Senescence-Associated Secretory Phenotype (SASP)";"HDACs deacetylate histones";"Golgi Associated Vesicle Biogenesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"PKMTs methylate histone lysines";"Packaging Of Telomere Ends";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deposition of new CENPA-containing nucleosomes at the centromere";"Pre-NOTCH Transcription and Translation";"HCMV Late Events";"NoRC negatively regulates rRNA expression";"DNA Damage/Telomere Stress Induced Senescence";"Transcriptional regulation by small RNAs";"Oxidative Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Meiotic synapsis";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"RNA Polymerase I Promoter Opening";"HDMs demethylate histones";"Processing of DNA double-strand break ends";"Estrogen-dependent gene expression";"SUMOylation of chromatin organization proteins";"Condensation of Prophase Chromosomes";"Formation of the beta-catenin:TCF transactivating complex";"Cleavage of the damaged pyrimidine";"B-WICH complex positively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"G2/M DNA damage checkpoint";"PRC2 methylates histones and DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RNA Polymerase I Promoter Escape";"Amyloid fiber formation";"DNA methylation";"HCMV Early Events";"HATs acetylate histones";"Transcriptional regulation of granulopoiesis";"RMTs methylate histone arginines" JAMg_model_12762.1 27 Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377 "SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins" JAMg_model_7420.2 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" JAMg_model_5470.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_1897.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_5904.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72706 "SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit" JAMg_model_9947.5 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_1040.3 1 Reactome: R-HSA-5620924 "Intraflagellar transport" JAMg_model_361.7 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" JAMg_model_1994.1 15 Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884;Reactome: R-HSA-8936459;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-2559580;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128 "Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"Oxidative Stress Induced Senescence";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling" JAMg_model_21165.2 7 Reactome: R-HSA-3108214;Reactome: R-HSA-2470946;Reactome: R-HSA-1221632;Reactome: R-HSA-2468052;Reactome: R-HSA-9018519;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "SUMOylation of DNA damage response and repair proteins";"Cohesin Loading onto Chromatin";"Meiotic synapsis";"Establishment of Sister Chromatid Cohesion";"Estrogen-dependent gene expression";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" JAMg_model_10854.5 6 Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693607 "HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends" JAMg_model_11575.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" JAMg_model_3553.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" JAMg_model_1467.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" JAMg_model_10134.8 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" JAMg_model_1758.1 6 Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-6814122 "Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" JAMg_model_361.2 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" JAMg_model_14657.1 4 Reactome: R-HSA-3371497;Reactome: R-HSA-8939211;Reactome: R-HSA-3371568;Reactome: R-HSA-9018519 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"ESR-mediated signaling";"Attenuation phase";"Estrogen-dependent gene expression" JAMg_model_6589.4 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" JAMg_model_440.2 1 Reactome: R-HSA-71384 "Ethanol oxidation" JAMg_model_14877.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" JAMg_model_16827.2 6 Reactome: R-HSA-6803207;Reactome: R-HSA-139915;Reactome: R-HSA-6803211;Reactome: R-HSA-6804759;Reactome: R-HSA-6803204;Reactome: R-HSA-6803205 "TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Death Receptors and Ligands";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain" JAMg_model_14654.5 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" JAMg_model_13715.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_20268.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_19093.1 7 MetaCyc: PWY-5188;Reactome: R-HSA-6782315;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.15;KEGG: 00860+6.1.1.17;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.17 "Tetrapyrrole biosynthesis I (from glutamate)";"tRNA modification in the nucleus and cytosol";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" JAMg_model_6708.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" JAMg_model_5107.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444 "Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" JAMg_model_8082.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" JAMg_model_20586.2 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" JAMg_model_11456.2 7 Reactome: R-HSA-72163;Reactome: R-HSA-6782135;MetaCyc: PWY-7511;Reactome: R-HSA-6781827;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210 "mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Protein ubiquitination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER" JAMg_model_18696.1 5 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-8964616;Reactome: R-HSA-416482;Reactome: R-HSA-446388 "NRAGE signals death through JNK";"Rho GTPase cycle";"G beta:gamma signalling through CDC42";"G alpha (12/13) signalling events";"Regulation of cytoskeletal remodeling and cell spreading by IPP complex components" JAMg_model_6028.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" JAMg_model_542.1 2 Reactome: R-HSA-446193;Reactome: R-HSA-4570571 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)" JAMg_model_11978.5 2 Reactome: R-HSA-5689880;MetaCyc: PWY-7511 "Ub-specific processing proteases";"Protein ubiquitination" JAMg_model_13054.8 4 MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Methionine salvage pathway" JAMg_model_3429.1 4 Reactome: R-HSA-975871;Reactome: R-HSA-975138;Reactome: R-HSA-6799198;Reactome: R-HSA-166058 "MyD88 cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"Complex I biogenesis";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane" JAMg_model_4349.2 8 Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-165054;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813 "SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids" JAMg_model_13054.3 3 KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" JAMg_model_4541.5 7 Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518 "Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2" JAMg_model_14652.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689 "Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" JAMg_model_8435.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_5303.3 4 Reactome: R-HSA-4755583;Reactome: R-HSA-446199;KEGG: 00510+2.7.1.108;MetaCyc: PWY-6129 "Defective DOLK causes DOLK-CDG (CDG-1m)";"Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis" JAMg_model_8938.1 6 Reactome: R-HSA-163210;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1268020;MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Oxidative phosphorylation";"Mitochondrial protein import";"ATP biosynthesis";"Photosynthesis";"Cristae formation" JAMg_model_16084.1 2 KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240 "Tryptophan metabolism";"Tryptophan catabolism" JAMg_model_8628.1 2 KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788 "Starch and sucrose metabolism";"Cellulose degradation II (fungi)" JAMg_model_21250.2 4 Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" JAMg_model_10101.2 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" JAMg_model_10093.4 1 Reactome: R-HSA-5620924 "Intraflagellar transport" JAMg_model_11786.1 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" JAMg_model_9310.3 4 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;Reactome: R-HSA-499943 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates" JAMg_model_17514.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_12723.2 2 KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281 "Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" JAMg_model_20198.1 4 MetaCyc: PWY-7494;MetaCyc: PWY-3722;Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1 "Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism";"Glycine, serine and threonine metabolism" JAMg_model_261.1 5 Reactome: R-HSA-4793954;MetaCyc: PWY-7918;MetaCyc: PWY-7919;Reactome: R-HSA-532668;KEGG: 00510+3.2.1.106 "Defective MOGS causes MOGS-CDG (CDG-2b)";"Protein N-glycosylation processing phase (yeast)";"Protein N-glycosylation processing phase (plants and animals)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"N-Glycan biosynthesis" JAMg_model_13352.1 24 Reactome: R-HSA-418217;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-381676;Reactome: R-HSA-428930;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-9009391;Reactome: R-HSA-392851;Reactome: R-HSA-4086398;Reactome: R-HSA-392170;Reactome: R-HSA-202040;Reactome: R-HSA-500657;Reactome: R-HSA-418555;Reactome: R-HSA-392451;Reactome: R-HSA-6814122;Reactome: R-HSA-416476;Reactome: R-HSA-8964315;Reactome: R-HSA-8964616;Reactome: R-HSA-420092;Reactome: R-HSA-418597;Reactome: R-HSA-400042;Reactome: R-HSA-416482 "G beta:gamma signalling through PLC beta";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thromboxane signalling through TP receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Extra-nuclear estrogen signaling";"Prostacyclin signalling through prostacyclin receptor";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 12";"G-protein activation";"Presynaptic function of Kainate receptors";"G alpha (s) signalling events";"G beta:gamma signalling through PI3Kgamma";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (q) signalling events";"G beta:gamma signalling through BTK";"G beta:gamma signalling through CDC42";"Glucagon-type ligand receptors";"G alpha (z) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (12/13) signalling events" JAMg_model_12723.1 2 KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281 "Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" JAMg_model_18681.5 1 KEGG: 00230+4.6.1.2 "Purine metabolism" JAMg_model_17942.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_6807.8 5 KEGG: 00720+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00630+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33 "Carbon fixation pathways in prokaryotes";"Iron uptake and transport";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis" JAMg_model_16083.1 2 MetaCyc: PWY-7800;MetaCyc: PWY-7799 "Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)" JAMg_model_11270.1 4 Reactome: R-HSA-3000170;Reactome: R-HSA-3000178;Reactome: R-HSA-216083;Reactome: R-HSA-2129379 "Syndecan interactions";"ECM proteoglycans";"Integrin cell surface interactions";"Molecules associated with elastic fibres" JAMg_model_10975.3 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" JAMg_model_4493.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" JAMg_model_10713.3 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" JAMg_model_11712.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_1709.2 3 Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-110312 "Translesion synthesis by POLI";"Translesion synthesis by POLK";"Translesion synthesis by REV1" JAMg_model_19670.2 5 Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-69205 "CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"G1/S-Specific Transcription" JAMg_model_13054.13 3 KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" JAMg_model_19003.3 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_7640.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_13088.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" JAMg_model_5281.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport" JAMg_model_11252.4 9 MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.94;KEGG: 00564+1.1.1.8;MetaCyc: PWY-5981;MetaCyc: PWY-6118;MetaCyc: PWY-5667;MetaCyc: PWY-7902 "Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis I";"Glucosylglycerol biosynthesis" JAMg_model_16773.2 27 Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638 "SUMOylation of RNA binding proteins";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins" JAMg_model_4909.2 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" JAMg_model_324.1 5 Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554 "HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" JAMg_model_7015.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_20791.3 14 Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-113418 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex" JAMg_model_10992.3 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" JAMg_model_13184.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_20117.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" JAMg_model_12337.4 26 Reactome: R-HSA-1989781;Reactome: R-HSA-5621575;Reactome: R-HSA-3134973;Reactome: R-HSA-2122947;Reactome: R-HSA-1368082;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-381340;Reactome: R-HSA-9617629;Reactome: R-HSA-2644606;Reactome: R-HSA-9614657;Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-918233;Reactome: R-HSA-9018519;Reactome: R-HSA-400253;Reactome: R-HSA-2894862;Reactome: R-HSA-8866907;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-3899300;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-933541;Reactome: R-HSA-201722 "PPARA activates gene expression";"CD209 (DC-SIGN) signaling";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH1 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"Transcriptional regulation of white adipocyte differentiation";"Regulation of FOXO transcriptional activity by acetylation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"FOXO-mediated transcription of cell death genes";"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TRAF3-dependent IRF activation pathway";"Estrogen-dependent gene expression";"Circadian Clock";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"SUMOylation of transcription cofactors";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"TRAF6 mediated IRF7 activation";"Formation of the beta-catenin:TCF transactivating complex" JAMg_model_5587.4 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" JAMg_model_980.3 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" JAMg_model_16809.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" JAMg_model_15678.1 26 MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-7606;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7854;MetaCyc: PWY-735;MetaCyc: PWY-7338;MetaCyc: PWY-7288;MetaCyc: PWY-7656;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858;KEGG: 00592+1.3.3.6;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7574;MetaCyc: PWY-7337;MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6;MetaCyc: PWY-5884;MetaCyc: PWY-6920;MetaCyc: PWY-7340;Reactome: R-HSA-9033241;MetaCyc: PWY-5136 "Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Propanoate metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Spodoptera littoralis pheromone biosynthesis";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II";"alpha-Linolenic acid metabolism";"Wax biosynthesis";"Plasmalogen biosynthesis";"Propanoyl-coa degradation II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism";"Wax esters biosynthesis I";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Peroxisomal protein import";"Fatty acid beta-oxidation II (plant peroxisome)" JAMg_model_16422.2 6 KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993;Reactome: R-HSA-418597;Reactome: R-HSA-5099900;Reactome: R-HSA-114516;Reactome: R-HSA-76005 "Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors";"G alpha (z) signalling events";"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+" JAMg_model_14464.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" JAMg_model_19967.1 1 MetaCyc: PWY-7379 "Mrna capping II" JAMg_model_18078.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" JAMg_model_11704.1 7 MetaCyc: PWY-6277;MetaCyc: PWY-6122;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6121;MetaCyc: PWY-7282;KEGG: 00250+2.4.2.14;Reactome: R-HSA-73817 "Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis" JAMg_model_4901.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" JAMg_model_11950.2 15 Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884;Reactome: R-HSA-9029569;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-2559580;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700 "Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" JAMg_model_13099.1 3 MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805 "Glyphosate degradation III";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation" JAMg_model_6101.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" JAMg_model_12281.2 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" JAMg_model_10204.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_14272.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" JAMg_model_21298.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_4008.1 4 Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" JAMg_model_19704.4 2 MetaCyc: PWY-6558;Reactome: R-HSA-2022928 "Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis" JAMg_model_20787.6 32 Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-168325;Reactome: R-HSA-6807505;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-167172;Reactome: R-HSA-8851708;Reactome: R-HSA-167238;Reactome: R-HSA-72086;Reactome: R-HSA-73776;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-75953;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-6803529;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-72203 "HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Viral Messenger RNA Synthesis";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"Transcription of the HIV genome";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Capping";"RNA Polymerase II Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Capped Intron-Containing Pre-mRNA" JAMg_model_1395.1 4 MetaCyc: PWY-7494;MetaCyc: PWY-3722;Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1 "Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism";"Glycine, serine and threonine metabolism" JAMg_model_19117.2 1 Reactome: R-HSA-200425 "Carnitine metabolism" JAMg_model_10821.2 3 MetaCyc: PWY-5691;KEGG: 00230+1.7.3.3;KEGG: 00232+1.7.3.3 "Urate conversion to allantoin I";"Purine metabolism";"Caffeine metabolism" JAMg_model_14757.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" JAMg_model_18337.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_974.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" JAMg_model_17286.1 6 Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817 "Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)" JAMg_model_16125.1 3 Reactome: R-HSA-6785470;Reactome: R-HSA-6784531;Reactome: R-HSA-8868766 "tRNA processing in the mitochondrion";"tRNA processing in the nucleus";"rRNA processing in the mitochondrion" JAMg_model_8811.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_9881.3 5 MetaCyc: PWY-5189;Reactome: R-HSA-189451;MetaCyc: PWY-7536;KEGG: 00260+2.3.1.37;KEGG: 00860+2.3.1.37 "Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Glycine, serine and threonine metabolism";"Porphyrin and chlorophyll metabolism" JAMg_model_14749.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_13194.3 4 Reactome: R-HSA-70895;KEGG: 00640+1.2.1.27;MetaCyc: PWY-5642;KEGG: 00280+1.2.1.27 "Branched-chain amino acid catabolism";"Propanoate metabolism";"2,4-dinitrotoluene degradation";"Valine, leucine and isoleucine degradation" JAMg_model_10409.4 3 Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network" JAMg_model_12749.8 12 Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-141444 "MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"HCMV Early Events";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" JAMg_model_14184.2 3 Reactome: R-HSA-6782315;MetaCyc: PWY-8106;MetaCyc: PWY-6700 "tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)" JAMg_model_17449.1 5 MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317 "Stachyose degradation";"Galactose metabolism";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)" JAMg_model_6932.3 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" JAMg_model_13394.4 7 Reactome: R-HSA-1483191;MetaCyc: PWY-7782;MetaCyc: PWY-3385;MetaCyc: PWY-7818;Reactome: R-HSA-1483213;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7886 "Synthesis of PC";"Plasmalogen biosynthesis";"Choline biosynthesis I";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Synthesis of PE";"Glycerophospholipid metabolism";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis" JAMg_model_7948.1 1 Reactome: R-HSA-350562 "Regulation of ornithine decarboxylase (ODC)" JAMg_model_20856.1 1 Reactome: R-HSA-6798163 "Choline catabolism" JAMg_model_12752.3 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" JAMg_model_20490.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7724 "Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" JAMg_model_6589.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" JAMg_model_5663.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" JAMg_model_17550.1 8 Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-8866652;Reactome: R-HSA-6782210;Reactome: R-HSA-8948747;Reactome: R-HSA-6781823 "Ub-specific processing proteases";"Regulation of TP53 Degradation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of PTEN localization";"Formation of TC-NER Pre-Incision Complex" JAMg_model_15815.1 5 Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-5545619;Reactome: R-HSA-201681;Reactome: R-HSA-8948751 "Ub-specific processing proteases";"Degradation of AXIN";"XAV939 inhibits tankyrase, stabilizing AXIN";"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity" JAMg_model_957.4 4 Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases activate KTN1";"Kinesins" JAMg_model_6375.5 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_16606.1 4 Reactome: R-HSA-379726;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716 "Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" JAMg_model_19797.2 1 Reactome: R-HSA-376172 "DSCAM interactions" JAMg_model_6409.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_10598.7 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689603 "Ub-specific processing proteases";"UCH proteinases" JAMg_model_642.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis" JAMg_model_16302.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" JAMg_model_4612.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" JAMg_model_4541.12 7 Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270 "AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" JAMg_model_8698.5 22 MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7049;MetaCyc: PWY-5080;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7053;MetaCyc: PWY-6958;MetaCyc: PWY-7606;MetaCyc: PWY-7726;MetaCyc: PWY-7035;MetaCyc: PWY-5353;MetaCyc: PWY-7727;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7592;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7728 "Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)" JAMg_model_14612.1 1 Reactome: R-HSA-3000171 "Non-integrin membrane-ECM interactions" JAMg_model_19757.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" JAMg_model_7186.3 18 MetaCyc: PWY-6642;KEGG: 00400+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-6638;MetaCyc: PWY-7117;KEGG: 00960+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-7383;KEGG: 00250+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00270+2.6.1.1;KEGG: 00401+2.6.1.1 "(R)-cysteate degradation";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Arginine and proline metabolism";"Carbon fixation in photosynthetic organisms";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"Phenylalanine metabolism";"Arginine biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Sulfolactate degradation III";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Coenzyme M biosynthesis II";"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine, aspartate and glutamate metabolism";"Partial TCA cycle (obligate autotrophs)";"Cysteine and methionine metabolism";"Novobiocin biosynthesis" JAMg_model_532.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling" JAMg_model_18425.1 17 MetaCyc: PWY-5451;KEGG: 00380+1.14.14.1;KEGG: 00071+1.14.14.1;MetaCyc: PWY-7466;KEGG: 00980+1.14.14.1;MetaCyc: PWY-6992;MetaCyc: PWY-5665;KEGG: 00591+1.14.14.1;KEGG: 00982+1.14.14.1;MetaCyc: PWY-7826;KEGG: 00830+1.14.14.1;MetaCyc: PWY-6398;Reactome: R-HSA-211981;KEGG: 00590+1.14.14.1;KEGG: 00140+1.14.14.1;KEGG: 00627+1.14.14.1;KEGG: 00232+1.14.14.1 "Acetone degradation I (to methylglyoxal)";"Tryptophan metabolism";"Fatty acid degradation";"Acetone degradation III (to propane-1,2-diol)";"Metabolism of xenobiotics by cytochrome P450";"1,5-anhydrofructose degradation";"Vanillin biosynthesis I";"Linoleic acid metabolism";"Drug metabolism - cytochrome P450";"Amaryllidacea alkaloids biosynthesis";"Retinol metabolism";"Melatonin degradation I";"Xenobiotics";"Arachidonic acid metabolism";"Steroid hormone biosynthesis";"Aminobenzoate degradation";"Caffeine metabolism" JAMg_model_8885.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" JAMg_model_1296.1 9 Reactome: R-HSA-110314;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-8951664;Reactome: R-HSA-5696400;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823 "Recognition of DNA damage by PCNA-containing replication complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Neddylation";"Dual Incision in GG-NER";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex" JAMg_model_5258.3 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" JAMg_model_327.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_20391.8 4 MetaCyc: PWY-7221;KEGG: 00230+6.3.5.2;KEGG: 00983+6.3.5.2;Reactome: R-HSA-73817 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis" JAMg_model_2678.1 3 MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism" JAMg_model_3201.1 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_2609.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" JAMg_model_18902.1 3 MetaCyc: PWY-1801;Reactome: R-HSA-156590;KEGG: 00680+3.1.2.12 "Formaldehyde oxidation II (glutathione-dependent)";"Glutathione conjugation";"Methane metabolism" JAMg_model_9369.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" JAMg_model_829.3 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" JAMg_model_13258.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" JAMg_model_16510.2 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" JAMg_model_19081.3 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" JAMg_model_8885.4 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" JAMg_model_5621.1 11 KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-163615 "Purine metabolism";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"PKA activation" JAMg_model_14659.2 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" JAMg_model_1507.2 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" JAMg_model_205.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_10656.2 3 Reactome: R-HSA-9645722;Reactome: R-HSA-140837;Reactome: R-HSA-111471 "Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Intrinsic Pathway of Fibrin Clot Formation";"Apoptotic factor-mediated response" JAMg_model_2104.1 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_16208.1 5 Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558 "ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis" JAMg_model_3715.3 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_10838.1 11 Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-174430;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-68952;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-68962;Reactome: R-HSA-5696397 "Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Telomere C-strand synthesis initiation";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"DNA replication initiation";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in GG-NER" JAMg_model_9054.7 3 KEGG: 00330+2.3.1.57;MetaCyc: PWY-6117;MetaCyc: PWY-0 "Arginine and proline metabolism";"Spermine and spermidine degradation I";"Putrescine degradation III" JAMg_model_7014.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_10841.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" JAMg_model_16884.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_3725.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" JAMg_model_3864.1 3 MetaCyc: PWY-7159;KEGG: 00860+1.3.3.4;Reactome: R-HSA-189451 "3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis" JAMg_model_13932.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" JAMg_model_16942.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" JAMg_model_3430.4 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" JAMg_model_2499.2 2 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" JAMg_model_15253.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" JAMg_model_3756.5 5 KEGG: 00564+2.7.8.5;Reactome: R-HSA-1483148;MetaCyc: PWY-7817;MetaCyc: PWY-5269;MetaCyc: PWY-5668 "Glycerophospholipid metabolism";"Synthesis of PG";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis II";"Cardiolipin biosynthesis I" JAMg_model_8491.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_7222.4 16 Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-9010553;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-8951664;Reactome: R-HSA-674695;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-167200;Reactome: R-HSA-983168;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167287 "RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Regulation of expression of SLITs and ROBOs";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Neddylation";"RNA Polymerase II Pre-transcription Events";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Antigen processing: Ubiquitination & Proteasome degradation";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery" JAMg_model_9396.1 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" JAMg_model_4637.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" JAMg_model_8361.3 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" JAMg_model_9089.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" JAMg_model_16589.5 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" JAMg_model_10507.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" JAMg_model_288.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" JAMg_model_7496.6 4 Reactome: R-HSA-2586552;Reactome: R-HSA-983231;Reactome: R-HSA-1170546;Reactome: R-HSA-982772 "Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production";"Prolactin receptor signaling";"Growth hormone receptor signaling" JAMg_model_16230.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339 "Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane" JAMg_model_1645.2 6 KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23 "Glycosaminoglycan degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Galactose metabolism" JAMg_model_18624.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs" JAMg_model_4974.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_19028.3 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_20300.1 8 Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5689880;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2565942 "Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Ub-specific processing proteases";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition" JAMg_model_19408.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_10129.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_19016.1 4 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes" JAMg_model_1554.1 8 Reactome: R-HSA-6803207;Reactome: R-HSA-6798695;Reactome: R-HSA-111464;Reactome: R-HSA-111458;Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-8953750;Reactome: R-HSA-111459 "TP53 Regulates Transcription of Caspase Activators and Caspases";"Neutrophil degranulation";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"Transcriptional Regulation by E2F6";"Activation of caspases through apoptosome-mediated cleavage" JAMg_model_447.2 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_13245.1 7 Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-5921;Reactome: R-HSA-210500;KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2 "TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism" JAMg_model_16418.1 4 Reactome: R-HSA-428540;Reactome: R-HSA-373753;Reactome: R-HSA-4420097;Reactome: R-HSA-186763 "Activation of RAC1";"Nephrin family interactions";"VEGFA-VEGFR2 Pathway";"Downstream signal transduction" JAMg_model_7864.2 3 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis" JAMg_model_15298.1 4 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Laminin interactions" JAMg_model_9084.2 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" JAMg_model_20864.4 12 KEGG: 00010+6.2.1.1;MetaCyc: PWY-7857;MetaCyc: PWY-5133;MetaCyc: PWY-5132;MetaCyc: PWY-6672;KEGG: 00680+6.2.1.1;KEGG: 00720+6.2.1.1;KEGG: 00620+6.2.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-5108;KEGG: 00630+6.2.1.1;KEGG: 00640+6.2.1.1 "Glycolysis / Gluconeogenesis";"Adlupulone and adhumulone biosynthesis";"Colupulone and cohumulone biosynthesis";"Lupulone and humulone biosynthesis";"Cis-genanyl-coa degradation";"Methane metabolism";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Chitin degradation to ethanol";"L-isoleucine biosynthesis V";"Glyoxylate and dicarboxylate metabolism";"Propanoate metabolism" JAMg_model_8308.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" JAMg_model_15391.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" JAMg_model_21058.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" JAMg_model_14488.1 8 KEGG: 00500+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00051+2.7.1.1 "Starch and sucrose metabolism";"Streptomycin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism" JAMg_model_12415.2 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" JAMg_model_12459.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-9633012 "Peptide chain elongation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" JAMg_model_13715.3 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_16087.1 2 KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240 "Tryptophan metabolism";"Tryptophan catabolism" JAMg_model_3576.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" JAMg_model_18910.5 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" JAMg_model_9665.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" JAMg_model_2884.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" JAMg_model_12860.1 4 Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism" JAMg_model_291.2 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_14654.2 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_2627.2 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" JAMg_model_2053.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" JAMg_model_6550.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" JAMg_model_5262.2 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" JAMg_model_18567.1 7 KEGG: 00051+5.4.2.8;MetaCyc: PWY-5659;MetaCyc: PWY-7456;MetaCyc: PWY-7586;KEGG: 00520+5.4.2.8;MetaCyc: PWY-882;Reactome: R-HSA-446205 "Fructose and mannose metabolism";"GDP-mannose biosynthesis";"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Amino sugar and nucleotide sugar metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Synthesis of GDP-mannose" JAMg_model_7998.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" JAMg_model_21292.1 17 MetaCyc: PWY-5690;MetaCyc: PWY-1622;KEGG: 00710+1.1.1.37;MetaCyc: PWY-561;KEGG: 00020+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-6969;MetaCyc: PWY-5913;KEGG: 00270+1.1.1.37;KEGG: 00720+1.1.1.37;KEGG: 00680+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-6728;KEGG: 00630+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-5392;MetaCyc: PWY-7115 "TCA cycle II (plants and fungi)";"Formaldehyde assimilation I (serine pathway)";"Carbon fixation in photosynthetic organisms";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Cysteine and methionine metabolism";"Carbon fixation pathways in prokaryotes";"Methane metabolism";"Pyruvate metabolism";"Methylaspartate cycle";"Glyoxylate and dicarboxylate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Reductive TCA cycle II";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" JAMg_model_15974.1 10 MetaCyc: PWY-7003;KEGG: 00710+2.7.2.3;Reactome: R-HSA-70171;Reactome: R-HSA-70263;MetaCyc: PWY-8004;MetaCyc: PWY-6886;KEGG: 00010+2.7.2.3;MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-6901 "Glycerol degradation to butanol";"Carbon fixation in photosynthetic organisms";"Glycolysis";"Gluconeogenesis";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation" JAMg_model_11352.2 2 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine, serine and threonine metabolism" JAMg_model_5106.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_11430.1 4 Reactome: R-HSA-3656532;Reactome: R-HSA-2173789;Reactome: R-HSA-2173788;Reactome: R-HSA-3304356 "TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer" JAMg_model_14518.3 1 Reactome: R-HSA-5620924 "Intraflagellar transport" JAMg_model_19896.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" JAMg_model_20738.3 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_17252.2 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" JAMg_model_13855.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_20787.2 32 Reactome: R-HSA-73776;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-76042;Reactome: R-HSA-6803529;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-72203;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-168325;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-167238;Reactome: R-HSA-72086 "RNA Polymerase II Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Viral Messenger RNA Synthesis";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Capping" JAMg_model_10727.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" JAMg_model_14755.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_9993.2 3 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" JAMg_model_306.1 11 Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-6807878;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-380259;Reactome: R-HSA-2132295;Reactome: R-HSA-380320 "Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"COPI-mediated anterograde transport";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of Nlp from mitotic centrosomes";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes" JAMg_model_116.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" JAMg_model_5403.2 13 Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Peptide chain elongation";"Viral mRNA Translation" JAMg_model_18928.1 4 Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-69205 "Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Unwinding of DNA";"G1/S-Specific Transcription" JAMg_model_788.1 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_20391.6 4 KEGG: 00983+6.3.5.2;Reactome: R-HSA-73817;KEGG: 00230+6.3.5.2;MetaCyc: PWY-7221 "Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" JAMg_model_1494.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" JAMg_model_7655.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" JAMg_model_6042.6 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" JAMg_model_6481.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" JAMg_model_651.1 3 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.5;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism" JAMg_model_8096.4 5 Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-168315 "RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Inhibition of Host mRNA Processing and RNA Silencing" JAMg_model_9164.1 4 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11;Reactome: R-HSA-379716;Reactome: R-HSA-2408557 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenocysteine synthesis" JAMg_model_14120.3 11 Reactome: R-HSA-4420097;KEGG: 05170+2.7.11.1;Reactome: R-HSA-171007;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-450302;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1 "VEGFA-VEGFR2 Pathway";"Human immunodeficiency virus 1 infection";"p38MAPK events";"Human cytomegalovirus infection";"Oxidative Stress Induced Senescence";"activated TAK1 mediates p38 MAPK activation";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway" JAMg_model_2590.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_6938.3 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_20509.2 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" JAMg_model_521.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_11904.7 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" JAMg_model_8986.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" JAMg_model_10021.5 4 KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841;KEGG: 00053+1.13.99.1;Reactome: R-HSA-1855183 "Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Ascorbate and aldarate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol" JAMg_model_16966.3 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" JAMg_model_3039.2 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_18158.2 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_10246.3 13 MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2022857;Reactome: R-HSA-2024101 "Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Keratan sulfate degradation";"CS/DS degradation" JAMg_model_11712.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_4353.1 15 Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-9603505;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"NTRK3 as a dependence receptor";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" JAMg_model_18656.1 15 Reactome: R-HSA-5693568;Reactome: R-HSA-5685939;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-2559586;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5693548;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-69473 "Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through MMEJ (alt-NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"DNA Damage/Telomere Stress Induced Senescence";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Sensing of DNA Double Strand Breaks";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint" JAMg_model_15139.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" JAMg_model_9488.1 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" JAMg_model_1192.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" JAMg_model_13400.4 10 Reactome: R-HSA-5684264;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-2565942;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091 "MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"Downstream TCR signaling";"Neddylation";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells" JAMg_model_6935.2 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" JAMg_model_5757.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_9054.1 3 MetaCyc: PWY-0;MetaCyc: PWY-6117;KEGG: 00330+2.3.1.57 "Putrescine degradation III";"Spermine and spermidine degradation I";"Arginine and proline metabolism" JAMg_model_12174.2 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" JAMg_model_3454.2 3 MetaCyc: PWY-6619;Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20 "Adenine and adenosine salvage VI";"Purine salvage";"Purine metabolism" JAMg_model_18381.1 7 KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6351;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6367 "Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism" JAMg_model_7190.1 12 KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-193648;Reactome: R-HSA-194840;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-418885;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416482 "PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"G alpha (q) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"DCC mediated attractive signaling";"Human immunodeficiency virus 1 infection";"G alpha (12/13) signalling events" JAMg_model_173.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" JAMg_model_11140.2 16 Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-176409;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-179409 "Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A" JAMg_model_4274.1 1 Reactome: R-HSA-6783984 "Glycine degradation" JAMg_model_9228.3 16 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-975956 "Peptide chain elongation";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" JAMg_model_2074.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" JAMg_model_5030.6 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" JAMg_model_2571.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" JAMg_model_829.4 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" JAMg_model_2842.4 17 Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-983168;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72706 "Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit" JAMg_model_11816.2 1 Reactome: R-HSA-70635 "Urea cycle" JAMg_model_12247.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_268.2 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" JAMg_model_8435.5 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_14338.1 5 KEGG: 00531+3.1.6.14;Reactome: R-HSA-432720;Reactome: R-HSA-6798695;Reactome: R-HSA-2206305;Reactome: R-HSA-2022857 "Glycosaminoglycan degradation";"Lysosome Vesicle Biogenesis";"Neutrophil degranulation";"MPS IIID - Sanfilippo syndrome D";"Keratan sulfate degradation" JAMg_model_14362.1 8 Reactome: R-HSA-191273;MetaCyc: PWY-6174;Reactome: R-HSA-2426168;MetaCyc: PWY-7391;MetaCyc: PWY-7524;KEGG: 00900+1.1.1.34;Reactome: R-HSA-1989781;MetaCyc: PWY-922 "Cholesterol biosynthesis";"Mevalonate pathway II (archaea)";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Terpenoid backbone biosynthesis";"PPARA activates gene expression";"Mevalonate pathway I" JAMg_model_21043.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" JAMg_model_14645.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" JAMg_model_21186.1 4 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)" JAMg_model_5024.2 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" JAMg_model_19535.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7724 "Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" JAMg_model_11816.1 1 Reactome: R-HSA-70635 "Urea cycle" JAMg_model_13363.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_11740.5 9 Reactome: R-HSA-174411;Reactome: R-HSA-6784531;Reactome: R-HSA-174430;Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-68962 "Polymerase switching on the C-strand of the telomere";"tRNA processing in the nucleus";"Telomere C-strand synthesis initiation";"Removal of the Flap Intermediate";"Polymerase switching";"DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex" JAMg_model_5358.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" JAMg_model_17940.1 3 Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691 "Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" JAMg_model_16863.1 3 Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" JAMg_model_5776.4 3 Reactome: R-HSA-2408508;Reactome: R-HSA-1614558;Reactome: R-HSA-1614603 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine" JAMg_model_20391.4 4 MetaCyc: PWY-7221;KEGG: 00230+6.3.5.2;KEGG: 00983+6.3.5.2;Reactome: R-HSA-73817 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis" JAMg_model_19110.1 2 Reactome: R-HSA-2142691;Reactome: R-HSA-2142700 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)" JAMg_model_4720.1 3 Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-110328 "Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" JAMg_model_8635.1 3 MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783 "Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" JAMg_model_11953.2 15 Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-8986944 "Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2" JAMg_model_12471.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72649 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Translation initiation complex formation" JAMg_model_10754.2 3 Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2 "VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway" JAMg_model_9948.4 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway" JAMg_model_8762.1 7 Reactome: R-HSA-4641262;Reactome: R-HSA-5368598;Reactome: R-HSA-201681;Reactome: R-HSA-5663220;Reactome: R-HSA-4086400;Reactome: R-HSA-4641258;Reactome: R-HSA-201688 "Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"TCF dependent signaling in response to WNT";"RHO GTPases Activate Formins";"PCP/CE pathway";"Degradation of DVL";"WNT mediated activation of DVL" JAMg_model_1040.7 1 Reactome: R-HSA-5620924 "Intraflagellar transport" JAMg_model_9987.2 4 Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257 "Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion" JAMg_model_14933.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-1358803;Reactome: R-HSA-983168 "Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_20594.2 10 Reactome: R-HSA-427413;Reactome: R-HSA-9022538;Reactome: R-HSA-983231;Reactome: R-HSA-9022699;Reactome: R-HSA-9022702;Reactome: R-HSA-8936459;Reactome: R-HSA-9615017;Reactome: R-HSA-400206;Reactome: R-HSA-3899300;Reactome: R-HSA-9022692 "NoRC negatively regulates rRNA expression";"Loss of MECP2 binding ability to 5mC-DNA";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates neuronal receptors and channels";"MECP2 regulates transcription of neuronal ligands";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of lipid metabolism by PPARalpha";"SUMOylation of transcription cofactors";"Regulation of MECP2 expression and activity" JAMg_model_829.2 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" JAMg_model_6246.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" JAMg_model_4371.4 5 Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;Reactome: R-HSA-164843;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695 "Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"2-LTR circle formation";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation" JAMg_model_19655.1 3 KEGG: 00860+2.5.1.141;MetaCyc: PWY-7856;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"Heme a biosynthesis";"Heme biosynthesis" JAMg_model_19147.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" JAMg_model_5262.1 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" JAMg_model_8159.3 12 KEGG: 00710+4.1.2.13;KEGG: 00680+4.1.2.13;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-7385;KEGG: 00051+4.1.2.13;KEGG: 00030+4.1.2.13;MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-6142;MetaCyc: PWY-1861;Reactome: R-HSA-70171 "Carbon fixation in photosynthetic organisms";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis" JAMg_model_21232.1 3 Reactome: R-HSA-5250924;Reactome: R-HSA-72165;Reactome: R-HSA-72163 "B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" JAMg_model_14541.1 4 Reactome: R-HSA-432720;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440 "Lysosome Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network" JAMg_model_3958.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" JAMg_model_15268.2 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_8159.7 12 Reactome: R-HSA-70171;MetaCyc: PWY-1861;MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00051+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00030+4.1.2.13;KEGG: 00710+4.1.2.13;KEGG: 00680+4.1.2.13;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70263 "Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Gluconeogenesis" JAMg_model_5658.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" JAMg_model_10020.1 4 KEGG: 00053+1.13.99.1;KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841;Reactome: R-HSA-1855183 "Ascorbate and aldarate metabolism";"Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Synthesis of IP2, IP, and Ins in the cytosol" JAMg_model_6341.1 7 KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis" JAMg_model_20973.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" JAMg_model_5924.5 3 Reactome: R-HSA-8951664;MetaCyc: PWY-7511;Reactome: R-HSA-349425 "Neddylation";"Protein ubiquitination";"Autodegradation of the E3 ubiquitin ligase COP1" JAMg_model_17486.1 2 Reactome: R-HSA-1362409;Reactome: R-HSA-1268020 "Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import" JAMg_model_1427.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" JAMg_model_647.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" JAMg_model_5941.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" JAMg_model_14770.1 9 MetaCyc: PWY-241;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-5743;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;MetaCyc: PWY-5789;MetaCyc: PWY-7115 "C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" JAMg_model_19438.2 2 Reactome: R-HSA-425397;Reactome: R-HSA-5619061 "Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)" JAMg_model_17739.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Peptide chain elongation" JAMg_model_10428.1 5 MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661 "2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation" JAMg_model_1293.4 6 MetaCyc: PWY-1622;MetaCyc: PWY-8004;KEGG: 00680+5.4.2.11;KEGG: 00260+5.4.2.11;KEGG: 00010+5.4.2.11;MetaCyc: PWY-5484 "Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Methane metabolism";"Glycine, serine and threonine metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)" JAMg_model_2717.1 2 KEGG: 00760+6.3.1.5;Reactome: R-HSA-196807 "Nicotinate and nicotinamide metabolism";"Nicotinate metabolism" JAMg_model_19617.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" JAMg_model_10881.4 4 Reactome: R-HSA-8934903;Reactome: R-HSA-1632852;Reactome: R-HSA-5205685;Reactome: R-HSA-936440 "Receptor Mediated Mitophagy";"Macroautophagy";"Pink/Parkin Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling" JAMg_model_19864.2 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" JAMg_model_1558.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" JAMg_model_16428.3 4 MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32 "Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism" JAMg_model_15253.2 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" JAMg_model_18337.3 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_19030.1 5 Reactome: R-HSA-389661;KEGG: 00250+1.2.1.88;KEGG: 00330+1.2.1.88;Reactome: R-HSA-70688;MetaCyc: PWY-6853 "Glyoxylate metabolism and glycine degradation";"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism";"Proline catabolism";"Ethylene biosynthesis II (microbes)" JAMg_model_16528.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" JAMg_model_19167.3 11 KEGG: 00565+3.1.3.4;MetaCyc: PWY-8051;Reactome: R-HSA-2029485;KEGG: 00561+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-8053;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052;KEGG: 00564+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8055 "Ether lipid metabolism";"Anandamide biosynthesis I";"Role of phospholipids in phagocytosis";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis" JAMg_model_10407.3 3 Reactome: R-HSA-6811440;Reactome: R-HSA-8876198;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic" JAMg_model_19822.2 19 MetaCyc: PWY-6728;KEGG: 00620+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-5392;MetaCyc: PWY-8086;KEGG: 00630+1.1.1.37;MetaCyc: PWY-561;KEGG: 00020+1.1.1.37;MetaCyc: PWY-7383;Reactome: R-HSA-70263;KEGG: 00710+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-5913;MetaCyc: PWY-6969;KEGG: 00720+1.1.1.37;KEGG: 00270+1.1.1.37 "Methylaspartate cycle";"Pyruvate metabolism";"Methane metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reductive TCA cycle II";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Glyoxylate and dicarboxylate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation I (serine pathway)";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Cysteine and methionine metabolism" JAMg_model_11904.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" JAMg_model_7222.3 16 Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-983168;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-674695;Reactome: R-HSA-8951664;Reactome: R-HSA-167238;Reactome: R-HSA-9010553;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167246 "Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Antigen processing: Ubiquitination & Proteasome degradation";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"RNA Polymerase II Pre-transcription Events";"Neddylation";"Pausing and recovery of Tat-mediated HIV elongation";"Regulation of expression of SLITs and ROBOs";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript" JAMg_model_5317.3 1 Reactome: R-HSA-71384 "Ethanol oxidation" JAMg_model_6026.3 3 Reactome: R-HSA-202427;Reactome: R-HSA-6798695;Reactome: R-HSA-6807004 "Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation";"Negative regulation of MET activity" JAMg_model_5284.2 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" JAMg_model_16572.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" JAMg_model_15838.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" JAMg_model_3191.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" JAMg_model_16815.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" JAMg_model_8025.1 10 Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568 "Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates" JAMg_model_5084.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" JAMg_model_1571.2 3 Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-390471 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Association of TriC/CCT with target proteins during biosynthesis" JAMg_model_365.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_13183.1 14 KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;Reactome: R-HSA-2022857;Reactome: R-HSA-194840;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883 "Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Keratan sulfate degradation";"Rho GTPase cycle";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II" JAMg_model_16029.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" JAMg_model_5091.2 16 MetaCyc: PWY-6142;KEGG: 00010+4.2.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-6901;MetaCyc: PWY-7124;MetaCyc: PWY-7218;MetaCyc: PWY-2221;Reactome: R-HSA-70171;MetaCyc: PWY-7003;KEGG: 00680+4.2.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-6886;MetaCyc: PWY-1622;MetaCyc: PWY-8004;MetaCyc: PWY-5723;Reactome: R-HSA-70263 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Ethylene biosynthesis V (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis";"Glycerol degradation to butanol";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Rubisco shunt";"Gluconeogenesis" JAMg_model_19866.2 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_19133.5 13 MetaCyc: PWY-5537;KEGG: 00720+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-5913;MetaCyc: PWY-5392;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-5538;MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5 "Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism" JAMg_model_16736.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" JAMg_model_20391.7 4 KEGG: 00230+6.3.5.2;MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2;Reactome: R-HSA-73817 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis" JAMg_model_17161.2 5 MetaCyc: PWY-6317;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527 "D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Stachyose degradation" JAMg_model_4998.6 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" JAMg_model_630.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" JAMg_model_5587.5 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" JAMg_model_19131.1 14 MetaCyc: PWY-8052;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-6453;MetaCyc: PWY-8051;KEGG: 00565+3.1.3.4;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483213;KEGG: 00600+3.1.3.4;Reactome: R-HSA-1483191;MetaCyc: PWY-8053;MetaCyc: PWY-7782;Reactome: R-HSA-75109;Reactome: R-HSA-4419969 "2-arachidonoylglycerol biosynthesis";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Ether lipid metabolism";"Glycerolipid metabolism";"Synthesis of PE";"Sphingolipid metabolism";"Synthesis of PC";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Triglyceride biosynthesis";"Depolymerisation of the Nuclear Lamina" JAMg_model_13056.5 13 Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation" JAMg_model_15187.3 5 Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897 "Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes" JAMg_model_10214.1 27 Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-168271 "Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus" JAMg_model_20576.3 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" JAMg_model_2678.2 3 MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism" JAMg_model_9723.1 1 Reactome: R-HSA-8949613 "Cristae formation" JAMg_model_8635.2 3 MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783 "Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" JAMg_model_13954.1 7 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway" JAMg_model_6355.1 4 Reactome: R-HSA-400511;Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-1799339 "Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane" JAMg_model_19071.1 29 Reactome: R-HSA-6804756;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-110312;Reactome: R-HSA-6783310;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-912446;Reactome: R-HSA-3371511;Reactome: R-HSA-3108214;Reactome: R-HSA-5685938;Reactome: R-HSA-5696395;Reactome: R-HSA-3371453;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-176187;Reactome: R-HSA-69166;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-68962;Reactome: R-HSA-174437;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-5696397 "Regulation of TP53 Activity through Phosphorylation";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Translesion synthesis by REV1";"Fanconi Anemia Pathway";"Translesion synthesis by POLK";"Dual incision in TC-NER";"Meiotic recombination";"HSF1 activation";"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)";"Formation of Incision Complex in GG-NER";"Regulation of HSF1-mediated heat shock response";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of ATR in response to replication stress";"Removal of the Flap Intermediate";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in GG-NER" JAMg_model_14736.3 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_19146.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" JAMg_model_947.2 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_15701.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_11139.1 4 MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14 "Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism" JAMg_model_9722.3 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" JAMg_model_9736.1 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" JAMg_model_16232.1 4 KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;MetaCyc: PWY-5912;Reactome: R-HSA-156581 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation" JAMg_model_13910.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" JAMg_model_3453.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_4574.2 2 Reactome: R-HSA-446203;Reactome: R-HSA-1799339 "Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane" JAMg_model_18100.7 1 Reactome: R-HSA-1632852 "Macroautophagy" JAMg_model_16474.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" JAMg_model_715.2 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" JAMg_model_3669.4 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" JAMg_model_13242.2 7 KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2;Reactome: R-HSA-5628897;MetaCyc: PWY-5921;Reactome: R-HSA-210500 "Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"TP53 Regulates Metabolic Genes";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle" JAMg_model_3318.3 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" JAMg_model_15895.1 7 Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-380972 "mTOR signalling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Macroautophagy";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK" JAMg_model_4101.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" JAMg_model_3327.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_9200.3 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" JAMg_model_9859.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" JAMg_model_19116.6 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_17984.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" JAMg_model_10712.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" JAMg_model_19051.1 2 Reactome: R-HSA-2299718;Reactome: R-HSA-2514853 "Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes" JAMg_model_1374.1 9 Reactome: R-HSA-3560783;Reactome: R-HSA-1971475;Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-2024096;Reactome: R-HSA-4420332;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237 "Defective B4GALT7 causes EDS, progeroid type";"A tetrasaccharide linker sequence is required for GAG synthesis";"Retinoid metabolism and transport";"HS-GAG biosynthesis";"HS-GAG degradation";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2" JAMg_model_8725.4 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" JAMg_model_8177.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" JAMg_model_2055.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385 "KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" JAMg_model_9989.1 4 Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257 "Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion" JAMg_model_14961.2 4 KEGG: 00785+2.8.1.8;Reactome: R-HSA-389661;MetaCyc: PWY-6987;MetaCyc: PWY-7382 "Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)" JAMg_model_8254.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" JAMg_model_12928.1 14 KEGG: 00190+1.3.5.1;MetaCyc: PWY-7279;Reactome: R-HSA-71403;Reactome: R-HSA-611105;KEGG: 00650+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-7254;MetaCyc: PWY-561;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6728;KEGG: 00020+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-4302;MetaCyc: PWY-5690 "Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Citric acid cycle (TCA cycle)";"Respiratory electron transport";"Butanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle VII (acetate-producers)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Aerobic respiration I (cytochrome c)";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle II (plants and fungi)" JAMg_model_16231.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" JAMg_model_3895.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" JAMg_model_17219.2 5 Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-8856825;Reactome: R-HSA-432722;Reactome: R-HSA-6798695 "Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Cargo recognition for clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis";"Neutrophil degranulation" JAMg_model_4786.1 6 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" JAMg_model_20832.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_18860.3 2 Reactome: R-HSA-8854214;Reactome: R-HSA-8873719 "TBC/RABGAPs";"RAB geranylgeranylation" JAMg_model_8210.5 6 Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits" JAMg_model_21295.3 7 MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7 "Justicidin B biosynthesis";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Betanidin degradation";"Phenylpropanoid biosynthesis" JAMg_model_5588.6 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" JAMg_model_1340.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" JAMg_model_11998.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" JAMg_model_12471.3 6 Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72649 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Translation initiation complex formation" JAMg_model_2017.6 5 Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21;Reactome: R-HSA-1368108;MetaCyc: PWY-5381;Reactome: R-HSA-197264 "Neutrophil degranulation";"Nicotinate and nicotinamide metabolism";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging" JAMg_model_18077.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" JAMg_model_13671.4 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" JAMg_model_7500.2 19 MetaCyc: PWY-7007;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7726;MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7338;MetaCyc: PWY-7291;MetaCyc: PWY-7854;MetaCyc: PWY-735;MetaCyc: PWY-6920;MetaCyc: PWY-7340;MetaCyc: PWY-5136;MetaCyc: PWY-7574;MetaCyc: PWY-7337;MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6 "Methyl ketone biosynthesis (engineered)";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoyl-coa degradation II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism" JAMg_model_11841.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-917729 "Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)" JAMg_model_64.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" JAMg_model_1960.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" JAMg_model_15812.5 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" JAMg_model_18015.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606 "HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" JAMg_model_16525.1 7 Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-69656 "G0 and Early G1";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry" JAMg_model_18048.7 5 KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;Reactome: R-HSA-70171;MetaCyc: PWY-6906;MetaCyc: PWY-5514 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Glycolysis";"Chitin derivatives degradation";"UDP-N-acetyl-D-galactosamine biosynthesis II" JAMg_model_9473.2 8 MetaCyc: PWY-5743;MetaCyc: PWY-7117;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-5789;MetaCyc: PWY-241;MetaCyc: PWY-5744 "3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation" JAMg_model_8897.5 3 Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-1268020 "Respiratory electron transport";"Complex I biogenesis";"Mitochondrial protein import" JAMg_model_10598.3 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5689880 "UCH proteinases";"Ub-specific processing proteases" JAMg_model_15493.2 20 MetaCyc: PWY-7007;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7726;MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7288;MetaCyc: PWY-7291;MetaCyc: PWY-7854;MetaCyc: PWY-735;MetaCyc: PWY-7340;MetaCyc: PWY-6920;MetaCyc: PWY-5136;Reactome: R-HSA-9033241;MetaCyc: PWY-7337;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837 "Methyl ketone biosynthesis (engineered)";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Peroxisomal protein import";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)" JAMg_model_14659.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" JAMg_model_958.1 3 Reactome: R-HSA-2022854;Reactome: R-HSA-5173105;Reactome: R-HSA-5083627 "Keratan sulfate biosynthesis";"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6" JAMg_model_19081.4 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" JAMg_model_16474.3 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" JAMg_model_17294.1 5 Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-168164 "TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade" JAMg_model_19272.6 2 KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921 "Histidine metabolism";"Histidine catabolism" JAMg_model_8098.5 1 Reactome: R-HSA-163841 "Gamma carboxylation, hypusine formation and arylsulfatase activation" JAMg_model_19607.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_13888.1 4 Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-400511 "Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)" JAMg_model_8843.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" JAMg_model_17732.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" JAMg_model_20873.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_4580.1 7 Reactome: R-HSA-191273;MetaCyc: PWY-6074;KEGG: 00100+1.3.1.70;MetaCyc: PWY-8026;Reactome: R-HSA-9022692;MetaCyc: PWY-7154;MetaCyc: PWY-2541 "Cholesterol biosynthesis";"Zymosterol biosynthesis";"Steroid biosynthesis";"Sterol biosynthesis (methylotrophs)";"Regulation of MECP2 expression and activity";"Ergosterol biosynthesis II";"Phytosterol biosynthesis (plants)" JAMg_model_2951.1 2 KEGG: 00040+5.3.1.5;KEGG: 00051+5.3.1.5 "Pentose and glucuronate interconversions";"Fructose and mannose metabolism" JAMg_model_14952.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_15277.4 10 MetaCyc: PWY-1722;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;MetaCyc: PWY-5497;MetaCyc: PWY-3841;MetaCyc: PWY-7909;MetaCyc: PWY-6613;Reactome: R-HSA-196757;MetaCyc: PWY-5030 "Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Folate transformations I";"Purine nucleobases degradation II (anaerobic)";"Folate transformations II (plants)";"Formaldehyde oxidation VII (THF pathway)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Metabolism of folate and pterines";"L-histidine degradation III" JAMg_model_19513.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" JAMg_model_17436.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_4835.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" JAMg_model_8210.4 6 Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689 "GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits" JAMg_model_985.2 3 Reactome: R-HSA-5628897;KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "TP53 Regulates Metabolic Genes";"Glutathione metabolism";"Detoxification of Reactive Oxygen Species" JAMg_model_13169.1 9 MetaCyc: PWY-5664;MetaCyc: PWY-5663;MetaCyc: PWY-6703;MetaCyc: PWY-7442;MetaCyc: PWY-7852;KEGG: 00790+3.5.4.16;Reactome: R-HSA-1474151;MetaCyc: PWY-6983;MetaCyc: PWY-6147 "Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I";"Preq0 biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Threo-tetrahydrobiopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I" JAMg_model_9043.4 9 Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"RORA activates gene expression";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis" JAMg_model_2629.2 2 KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111 "Fatty acid degradation";"Mitochondrial L-carnitine shuttle" JAMg_model_18048.5 5 Reactome: R-HSA-70171;MetaCyc: PWY-5514;MetaCyc: PWY-6906;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6 "Glycolysis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism" JAMg_model_14443.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" JAMg_model_17862.1 56 Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-4641258 "ABC-family proteins mediated transport";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL" JAMg_model_13892.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" JAMg_model_14839.1 31 MetaCyc: PWYG-321;MetaCyc: PWY-5367;MetaCyc: PWY-7746;Reactome: R-HSA-199220;MetaCyc: PWY-5994;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5366;MetaCyc: PWY-7723;MetaCyc: PWY-7388;MetaCyc: PWY-7663;MetaCyc: PWY-5971;MetaCyc: PWY-7858;MetaCyc: PWY-8047;MetaCyc: PWY-8049;Reactome: R-HSA-163765;MetaCyc: PWY-5142;MetaCyc: PWY-5989;MetaCyc: PWY-5147;Reactome: R-HSA-9029558;MetaCyc: PWY-5966-1;MetaCyc: PWY-7664;MetaCyc: PWY-5973;Reactome: R-HSA-75105;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6282;MetaCyc: PWY-6113;MetaCyc: PWY-4381;MetaCyc: PWY-6519;MetaCyc: PWY-8012;Reactome: R-HSA-2426168;MetaCyc: PWY-6799 "";"Petroselinate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Fatty acid biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Bacterial bioluminescence";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Gondoate biosynthesis (anaerobic)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"(5Z)-dodecenoate biosynthesis II";"Bryostatin biosynthesis";"Pederin biosynthesis";"ChREBP activates metabolic gene expression";"Acyl-[acyl-carrier protein] thioesterase pathway";"Stearate biosynthesis II (bacteria and plants)";"Oleate biosynthesis I (plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Oleate biosynthesis IV (anaerobic)";"Cis-vaccenate biosynthesis";"Fatty acyl-CoA biosynthesis";"Biotin metabolism";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Superpathway of mycolate biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"Mupirocin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (plant mitochondria)" JAMg_model_7691.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6783310 "Protein ubiquitination";"Fanconi Anemia Pathway" JAMg_model_5645.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" JAMg_model_16331.1 9 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"tRNA modification in the nucleus and cytosol";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation" JAMg_model_21105.1 4 Reactome: R-HSA-936440;Reactome: R-HSA-5205685;Reactome: R-HSA-1632852;Reactome: R-HSA-8934903 "Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy";"Macroautophagy";"Receptor Mediated Mitophagy" JAMg_model_6181.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" JAMg_model_9054.3 3 MetaCyc: PWY-6117;KEGG: 00330+2.3.1.57;MetaCyc: PWY-0 "Spermine and spermidine degradation I";"Arginine and proline metabolism";"Putrescine degradation III" JAMg_model_11483.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" JAMg_model_650.2 4 KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;Reactome: R-HSA-351202 "Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Metabolism of polyamines" JAMg_model_1124.5 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" JAMg_model_17812.1 1 Reactome: R-HSA-6798163 "Choline catabolism" JAMg_model_2310.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_4116.3 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" JAMg_model_10824.3 12 MetaCyc: PWY-6683;KEGG: 00920+2.7.1.25;KEGG: 00230+2.7.7.4;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5340;MetaCyc: PWY-6932;MetaCyc: PWY-5278;KEGG: 00920+2.7.7.4;KEGG: 00230+2.7.1.25;Reactome: R-HSA-174362;Reactome: R-HSA-2408550;KEGG: 00450+2.7.7.4 "Assimilatory sulfate reduction III";"Sulfur metabolism";"Purine metabolism";"Monobactam biosynthesis";"Sulfate activation for sulfonation";"Selenate reduction";"Sulfite oxidation III";"Sulfur metabolism";"Purine metabolism";"Transport and synthesis of PAPS";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Selenocompound metabolism" JAMg_model_19398.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_11704.2 7 KEGG: 00230+2.4.2.14;MetaCyc: PWY-6122;MetaCyc: PWY-6277;MetaCyc: PWY-6121;MetaCyc: PWY-7282;KEGG: 00250+2.4.2.14;Reactome: R-HSA-73817 "Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis" JAMg_model_14445.3 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" JAMg_model_19655.3 3 Reactome: R-HSA-189451;MetaCyc: PWY-7856;KEGG: 00860+2.5.1.141 "Heme biosynthesis";"Heme a biosynthesis";"Porphyrin and chlorophyll metabolism" JAMg_model_3399.1 12 Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-1368082;Reactome: R-HSA-383280;Reactome: R-HSA-400253;Reactome: R-HSA-212436;Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-3371453;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Estrogen-dependent gene expression";"RORA activates gene expression";"Nuclear Receptor transcription pathway";"Circadian Clock";"Generic Transcription Pathway";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"Regulation of HSF1-mediated heat shock response";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis" JAMg_model_13671.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_14757.3 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" JAMg_model_745.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" JAMg_model_18047.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" JAMg_model_21161.3 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942 "Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition" JAMg_model_957.2 4 Reactome: R-HSA-6811434;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1";"MHC class II antigen presentation";"Kinesins" JAMg_model_3789.3 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" JAMg_model_13400.2 10 Reactome: R-HSA-5684264;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-2565942;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091 "MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"Downstream TCR signaling";"Neddylation";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells" JAMg_model_9755.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" JAMg_model_8298.2 4 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-1912420 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi" JAMg_model_15268.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_8921.1 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_8935.2 4 Reactome: R-HSA-3108214;Reactome: R-HSA-532668;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394 "SUMOylation of DNA damage response and repair proteins";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER" JAMg_model_8730.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" JAMg_model_12033.1 5 KEGG: 00520+3.2.1.14;Reactome: R-HSA-156588;MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855 "Amino sugar and nucleotide sugar metabolism";"Glucuronidation";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)" JAMg_model_3210.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" JAMg_model_12749.5 12 Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-68877 "COPI-mediated anterograde transport";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"RHO GTPases Activate Formins";"HCMV Early Events";"Mitotic Prometaphase" JAMg_model_18440.3 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" JAMg_model_7738.1 3 MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism" JAMg_model_12281.4 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" JAMg_model_20866.2 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_5067.2 1 Reactome: R-HSA-8949613 "Cristae formation" JAMg_model_6326.2 14 Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167200 "Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat" JAMg_model_551.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" JAMg_model_20818.1 5 Reactome: R-HSA-3214858;Reactome: R-HSA-1266695;Reactome: R-HSA-3247509;Reactome: R-HSA-8939243;Reactome: R-HSA-201722 "RMTs methylate histone arginines";"Interleukin-7 signaling";"Chromatin modifying enzymes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex" JAMg_model_19503.2 58 KEGG: 00592+4.2.1.17;MetaCyc: PWY-7401;MetaCyc: PWY-7726;KEGG: 00071+4.2.1.17+1.1.1.35;Reactome: R-HSA-77350;MetaCyc: PWY-5109;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;Reactome: R-HSA-77285;MetaCyc: PWY-6944;KEGG: 00903+4.2.1.17;KEGG: 00650+4.2.1.17;Reactome: R-HSA-77348;MetaCyc: PWY-5177;MetaCyc: PWY-6583;MetaCyc: PWY-5138;Reactome: R-HSA-77346;KEGG: 00627+4.2.1.17;KEGG: 00410+4.2.1.17;KEGG: 00281+4.2.1.17;Reactome: R-HSA-1482798;KEGG: 00362+4.2.1.17;KEGG: 00360+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;MetaCyc: PWY-6883;MetaCyc: PWY-7216;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.211;MetaCyc: PWY-7779;KEGG: 00930+4.2.1.17;MetaCyc: PWY-7606;KEGG: 00640+4.2.1.17;KEGG: 00310+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7778;MetaCyc: PWY-6945;MetaCyc: PWY-6435;KEGG: 00650+4.2.1.17+1.1.1.35;Reactome: R-HSA-77288;KEGG: 00280+4.2.1.17;MetaCyc: PWY-7654;Reactome: R-HSA-77310;KEGG: 00062+4.2.1.17+1.1.1.211;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17;MetaCyc: PWY-5136;Reactome: R-HSA-77305;MetaCyc: PWY-6863;MetaCyc: PWY-6946;MetaCyc: PWY-7094 "alpha-Linolenic acid metabolism";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid degradation";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Fermentation to 2-methylbutanoate";"Benzoate degradation";"Tryptophan metabolism";"Tryptophan metabolism";"Methyl ketone biosynthesis (engineered)";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Androstenedione degradation";"Limonene and pinene degradation";"Butanoate metabolism";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Glutaryl-coa degradation";"Pyruvate fermentation to butanol I";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Aminobenzoate degradation";"beta-Alanine metabolism";"Geraniol degradation";"Acyl chain remodeling of CL";"Benzoate degradation";"Phenylalanine metabolism";"Lysine degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Valine, leucine and isoleucine degradation";"Spodoptera littoralis pheromone biosynthesis";"Pyruvate fermentation to butanol II (engineered)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Carbon fixation pathways in prokaryotes";"Caprolactam degradation";"Fatty acid degradation";"Methyl tert-butyl ether degradation";"Caprolactam degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"Lysine degradation";"Geraniol degradation";"Benzoyl-coa degradation I (aerobic)";"Toluene degradation";"2-methylpropene degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"4-hydroxybenzoate biosynthesis III (plants)";"Butanoate metabolism";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Valine, leucine and isoleucine degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Fatty acid elongation";"Fatty acid elongation";"Carbon fixation pathways in prokaryotes";"Fatty acid beta-oxidation II (plant peroxisome)";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Pyruvate fermentation to hexanol (engineered)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Fatty acid salvage" JAMg_model_6691.4 6 MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" JAMg_model_13671.5 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_10663.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" JAMg_model_14061.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" JAMg_model_12479.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_10492.4 1 Reactome: R-HSA-110357 "Displacement of DNA glycosylase by APEX1" JAMg_model_20866.1 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_10797.8 1 Reactome: R-HSA-5676934 "Protein repair" JAMg_model_15677.1 33 Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-141444;Reactome: R-HSA-4085377;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-4551638 "Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of SUMOylation proteins";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins" JAMg_model_18156.3 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" JAMg_model_3425.2 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" JAMg_model_3005.1 52 Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-180534 "Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Orc1 removal from chromatin";"ABC-family proteins mediated transport";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4" JAMg_model_20521.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" JAMg_model_12493.1 4 MetaCyc: PWY-7849;MetaCyc: PWY-7394;KEGG: 00230+4.1.1.97;MetaCyc: PWY-5691 "Urate conversion to allantoin III";"Urate conversion to allantoin II";"Purine metabolism";"Urate conversion to allantoin I" JAMg_model_3349.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" JAMg_model_11299.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_12764.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-975956 "Viral mRNA Translation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" JAMg_model_4371.5 5 Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949 "Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA" JAMg_model_15768.1 5 MetaCyc: PWY-7426;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.68;KEGG: 00533+2.4.1.68;KEGG: 00513+2.4.1.68 "Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate";"Various types of N-glycan biosynthesis" JAMg_model_10683.4 1 Reactome: R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" JAMg_model_6324.6 10 KEGG: 00564+2.3.1.15;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-8051 "Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I" JAMg_model_11719.2 7 Reactome: R-HSA-174403;MetaCyc: PWY-6840;Reactome: R-HSA-5578999;KEGG: 00480+6.3.2.2;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.2;MetaCyc: PWY-7255 "Glutathione synthesis and recycling";"Homoglutathione biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione metabolism";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Ergothioneine biosynthesis I (bacteria)" JAMg_model_16527.2 11 MetaCyc: PWY-5675;KEGG: 00630+6.3.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-6963;MetaCyc: PWY-381;KEGG: 00220+6.3.1.2;Reactome: R-HSA-210455;MetaCyc: PWY-6964;MetaCyc: PWY-6549;KEGG: 00250+6.3.1.2;KEGG: 00910+6.3.1.2 "Nitrate reduction V (assimilatory)";"Glyoxylate and dicarboxylate metabolism";"Glutamate and glutamine metabolism";"Ammonia assimilation cycle I";"Nitrate reduction II (assimilatory)";"Arginine biosynthesis";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Ammonia assimilation cycle II";"L-glutamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism" JAMg_model_12926.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" JAMg_model_1340.2 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" JAMg_model_15935.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" JAMg_model_14870.2 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" JAMg_model_268.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" JAMg_model_18332.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_4401.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" JAMg_model_650.5 4 Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16 "Metabolism of polyamines";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism" JAMg_model_3741.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_9978.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" JAMg_model_12586.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" JAMg_model_1143.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8869496 "Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" JAMg_model_14327.1 2 Reactome: R-HSA-975956;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" JAMg_model_6485.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" JAMg_model_10980.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444 "Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" JAMg_model_8153.6 3 KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3 "Methane metabolism";"Serine biosynthesis";"Glycine, serine and threonine metabolism" JAMg_model_12111.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" JAMg_model_13657.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" JAMg_model_9900.5 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" JAMg_model_18158.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_15154.7 1 KEGG: 00051+4.2.1.68 "Fructose and mannose metabolism" JAMg_model_8502.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" JAMg_model_15494.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" JAMg_model_3981.2 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" JAMg_model_14567.1 1 Reactome: R-HSA-191859 "snRNP Assembly" JAMg_model_12710.3 6 MetaCyc: PWY-6907;Reactome: R-HSA-196819;MetaCyc: PWY-6898;MetaCyc: PWY-7356;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6908 "Thiamine diphosphate biosynthesis III (Staphylococcus)";"Vitamin B1 (thiamin) metabolism";"Thiamine salvage III";"Thiamine salvage IV (yeast)";"Thiamine metabolism";"Thiamine diphosphate biosynthesis IV (eukaryotes)" JAMg_model_11050.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257 "Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion" JAMg_model_17337.2 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" JAMg_model_13671.3 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_5804.2 2 KEGG: 00260+4.3.1.19;KEGG: 00290+4.3.1.19 "Glycine, serine and threonine metabolism";"Valine, leucine and isoleucine biosynthesis" JAMg_model_8153.3 3 Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3 "Serine biosynthesis";"Methane metabolism";"Glycine, serine and threonine metabolism" JAMg_model_10530.1 8 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-983168 "Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_115.1 3 KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646;Reactome: R-HSA-5579007 "Arginine biosynthesis";"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy" JAMg_model_65.2 3 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism" JAMg_model_692.1 10 Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-3214847;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6804756 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"HATs acetylate histones";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation" JAMg_model_16660.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" JAMg_model_4350.3 1 Reactome: R-HSA-8949664 "Processing of SMDT1" JAMg_model_11694.2 11 Reactome: R-HSA-5663213;Reactome: R-HSA-428890;Reactome: R-HSA-2029482;Reactome: R-HSA-525793;Reactome: R-HSA-5685938;Reactome: R-HSA-8940973;Reactome: R-HSA-8939236;Reactome: R-HSA-69231;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5693565;Reactome: R-HSA-983231 "RHO GTPases Activate WASPs and WAVEs";"Role of ABL in ROBO-SLIT signaling";"Regulation of actin dynamics for phagocytic cup formation";"Myogenesis";"HDR through Single Strand Annealing (SSA)";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin D associated events in G1";"T cell receptor signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Factors involved in megakaryocyte development and platelet production" JAMg_model_4464.4 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" JAMg_model_15505.2 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" JAMg_model_20249.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" JAMg_model_16822.1 34 Reactome: R-HSA-69202;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167162;Reactome: R-HSA-69231;Reactome: R-HSA-73762;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-5696395;Reactome: R-HSA-75953;Reactome: R-HSA-6782135;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-69656;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-8939236;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-69273;Reactome: R-HSA-6781827;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-427413;Reactome: R-HSA-167160 "Cyclin E associated events during G1/S transition";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Cyclin D associated events in G1";"RNA Polymerase I Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation";"Dual incision in TC-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Cyclin A/B1/B2 associated events during G2/M transition";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection" JAMg_model_5574.7 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" JAMg_model_7186.1 18 KEGG: 00950+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-6638;MetaCyc: PWY-7115;KEGG: 00220+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-6643;KEGG: 00401+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00250+2.6.1.1 "Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"Carbon fixation in photosynthetic organisms";"Arginine and proline metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"(R)-cysteate degradation";"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Sulfolactate degradation III";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Arginine biosynthesis";"Phenylalanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Coenzyme M biosynthesis II";"Novobiocin biosynthesis";"Cysteine and methionine metabolism";"Partial TCA cycle (obligate autotrophs)";"Alanine, aspartate and glutamate metabolism" JAMg_model_14389.1 18 KEGG: 00280+1.8.1.4;KEGG: 00620+1.8.1.4;Reactome: R-HSA-6783984;KEGG: 00640+1.8.1.4;KEGG: 00310+1.8.1.4;KEGG: 00020+1.8.1.4;KEGG: 00010+1.8.1.4;Reactome: R-HSA-204174;MetaCyc: PWY-5084;MetaCyc: PWY-5046;Reactome: R-HSA-71064;Reactome: R-HSA-5362517;KEGG: 00380+1.8.1.4;Reactome: R-HSA-70895;Reactome: R-HSA-70268;Reactome: R-HSA-389661;KEGG: 00260+1.8.1.4;Reactome: R-HSA-71403 "Valine, leucine and isoleucine degradation";"Pyruvate metabolism";"Glycine degradation";"Propanoate metabolism";"Lysine degradation";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"2-oxoglutarate decarboxylation to succinyl-CoA";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Lysine catabolism";"Signaling by Retinoic Acid";"Tryptophan metabolism";"Branched-chain amino acid catabolism";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Glycine, serine and threonine metabolism";"Citric acid cycle (TCA cycle)" JAMg_model_10201.5 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_7404.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" JAMg_model_3666.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_4026.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" JAMg_model_8478.4 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" JAMg_model_3117.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" JAMg_model_13056.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012 "L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency" JAMg_model_19131.2 14 Reactome: R-HSA-1483191;MetaCyc: PWY-8053;MetaCyc: PWY-7782;KEGG: 00600+3.1.3.4;Reactome: R-HSA-4419969;Reactome: R-HSA-75109;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8051;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483213;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-6453;MetaCyc: PWY-8052 "Synthesis of PC";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Sphingolipid metabolism";"Depolymerisation of the Nuclear Lamina";"Triglyceride biosynthesis";"Ether lipid metabolism";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Synthesis of PE";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"2-arachidonoylglycerol biosynthesis" JAMg_model_2059.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" JAMg_model_7280.1 2 KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753 "Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism" JAMg_model_17268.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" JAMg_model_7428.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" JAMg_model_13056.3 13 Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" JAMg_model_3507.2 4 Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878 "MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport" JAMg_model_14769.1 2 Reactome: R-HSA-212676;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" JAMg_model_2676.1 5 Reactome: R-HSA-3249367;Reactome: R-HSA-3270619;Reactome: R-HSA-1834941;Reactome: R-HSA-6798695;Reactome: R-HSA-3134975 "STAT6-mediated induction of chemokines";"IRF3-mediated induction of type I IFN";"STING mediated induction of host immune responses";"Neutrophil degranulation";"Regulation of innate immune responses to cytosolic DNA" JAMg_model_19960.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" JAMg_model_3732.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_15766.1 17 Reactome: R-HSA-174437;Reactome: R-HSA-5358606;Reactome: R-HSA-69183;Reactome: R-HSA-5358565;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-174417;Reactome: R-HSA-6782210;Reactome: R-HSA-69166;Reactome: R-HSA-110314;Reactome: R-HSA-174414;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-6782135 "Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processive synthesis on the lagging strand";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Telomere C-strand (Lagging Strand) Synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate";"Recognition of DNA damage by PCNA-containing replication complex";"Processive synthesis on the C-strand of the telomere";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Polymerase switching";"Dual incision in TC-NER" JAMg_model_14998.2 3 Reactome: R-HSA-3299685;KEGG: 00240+3.6.1.17;KEGG: 00230+3.6.1.17 "Detoxification of Reactive Oxygen Species";"Pyrimidine metabolism";"Purine metabolism" JAMg_model_2010.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" JAMg_model_18297.1 7 MetaCyc: PWY-7238;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6724;MetaCyc: PWY-6737;Reactome: R-HSA-6798695;MetaCyc: PWY-5941;Reactome: R-HSA-70221 "Sucrose biosynthesis II";"Starch and sucrose metabolism";"Starch degradation II";"Starch degradation V";"Neutrophil degranulation";"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)" JAMg_model_12692.1 1 Reactome: R-HSA-9022692 "Regulation of MECP2 expression and activity" JAMg_model_15081.2 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" JAMg_model_1273.1 2 Reactome: R-HSA-216083;Reactome: R-HSA-8951664 "Integrin cell surface interactions";"Neddylation" JAMg_model_15634.1 3 Reactome: R-HSA-8854691;KEGG: 04660+2.7.10.2;Reactome: R-HSA-6785807 "Interleukin-20 family signaling";"T cell receptor signaling pathway";"Interleukin-4 and Interleukin-13 signaling" JAMg_model_6815.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation" JAMg_model_16718.1 1 Reactome: R-HSA-2514859 "Inactivation, recovery and regulation of the phototransduction cascade" JAMg_model_6415.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_4688.2 8 KEGG: 00240+2.7.4.9;MetaCyc: PWY-7184;MetaCyc: PWY-7197;Reactome: R-HSA-499943;MetaCyc: PWY-6545;MetaCyc: PWY-7210;MetaCyc: PWY-7187;MetaCyc: PWY-7198 "Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" JAMg_model_4402.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_13140.3 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_19425.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" JAMg_model_15764.1 37 Reactome: R-HSA-204005;Reactome: R-HSA-4551638;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-2132295;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-4085377;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-983170;Reactome: R-HSA-9639288;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-68877;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142 "COPII-mediated vesicle transport";"SUMOylation of chromatin organization proteins";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"MHC class II antigen presentation";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of SUMOylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Amino acids regulate mTORC1";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Mitotic Prometaphase";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins" JAMg_model_9184.7 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism" JAMg_model_18434.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_7098.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" JAMg_model_19638.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706 "Viral mRNA Translation";"Peptide chain elongation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit" JAMg_model_8393.1 2 Reactome: R-HSA-2408508;Reactome: R-HSA-389661 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation" JAMg_model_4874.5 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" JAMg_model_18071.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" JAMg_model_5433.3 4 Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport" JAMg_model_18323.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-936440 "Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling" JAMg_model_9289.1 3 Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine" JAMg_model_9396.4 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" JAMg_model_13968.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" JAMg_model_18681.7 1 KEGG: 00230+4.6.1.2 "Purine metabolism" JAMg_model_15097.3 8 Reactome: R-HSA-983712;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-1222556;Reactome: R-HSA-9636467;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-9639288 "Ion channel transport";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"ROS and RNS production in phagocytes";"Blockage of phagosome acidification";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1" JAMg_model_17666.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" JAMg_model_15664.1 2 Reactome: R-HSA-70171;Reactome: R-HSA-70263 "Glycolysis";"Gluconeogenesis" JAMg_model_20416.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" JAMg_model_617.1 9 Reactome: R-HSA-110314;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395 "Recognition of DNA damage by PCNA-containing replication complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER" JAMg_model_10182.4 5 Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-983231;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Factors involved in megakaryocyte development and platelet production";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic" JAMg_model_6752.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" JAMg_model_19795.2 4 KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.6 "Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"Metabolism of folate and pterines";"One carbon pool by folate" JAMg_model_19224.1 1 Reactome: R-HSA-5676934 "Protein repair" JAMg_model_10889.2 8 KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1 "Galactose metabolism";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Glycolysis";"Amino sugar and nucleotide sugar metabolism" JAMg_model_20334.10 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" JAMg_model_5657.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" JAMg_model_552.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" JAMg_model_17870.1 56 Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-1236978;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-350562;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-8939902;Reactome: R-HSA-349425 "Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of ornithine decarboxylase (ODC)";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1" JAMg_model_13196.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" JAMg_model_258.3 5 Reactome: R-HSA-5610785;Reactome: R-HSA-5610787;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780 "GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'off' state";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome" JAMg_model_3468.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" JAMg_model_6326.1 14 Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167246 "Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript" JAMg_model_13403.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" JAMg_model_10817.3 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" JAMg_model_20941.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" JAMg_model_14883.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" JAMg_model_20972.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" JAMg_model_4185.2 2 Reactome: R-HSA-70350;Reactome: R-HSA-168928 "Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta" JAMg_model_20205.4 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" JAMg_model_2692.1 15 MetaCyc: PWY-4983;MetaCyc: PWY-6824;KEGG: 00250+4.3.2.1;MetaCyc: PWY-5461;MetaCyc: PWY-4984;Reactome: R-HSA-70635;MetaCyc: PWY-5154;MetaCyc: PWY-5469;MetaCyc: PWY-5;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-7214;KEGG: 00220+4.3.2.1;MetaCyc: PWY-7400;KEGG: 00940+1.11.1.7 "Nitric oxide biosynthesis II (mammals)";"Justicidin B biosynthesis";"Alanine, aspartate and glutamate metabolism";"Betanidin degradation";"Urea cycle";"Urea cycle";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Sesamin biosynthesis";"Canavanine biosynthesis";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Arginine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"Phenylpropanoid biosynthesis" JAMg_model_8304.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_8363.3 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" JAMg_model_218.3 1 Reactome: R-HSA-73621 "Pyrimidine catabolism" JAMg_model_17781.2 1 Reactome: R-HSA-611105 "Respiratory electron transport" JAMg_model_7864.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis" JAMg_model_7863.2 13 MetaCyc: PWY-5537;Reactome: R-HSA-71403;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-6969;MetaCyc: PWY-5913;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690 "Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)" JAMg_model_10547.4 6 Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257 "Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion" JAMg_model_12356.1 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" JAMg_model_8992.2 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_10816.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_2584.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" JAMg_model_9820.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" JAMg_model_18564.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" JAMg_model_6913.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_12370.2 6 MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-6722;MetaCyc: PWY-4381;Reactome: R-HSA-196780 "Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Biotin transport and metabolism" JAMg_model_17195.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" JAMg_model_15508.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" JAMg_model_15204.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" JAMg_model_16589.7 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" JAMg_model_7304.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" JAMg_model_13230.3 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" JAMg_model_19431.3 13 Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957 "Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" JAMg_model_6635.1 1 Reactome: R-HSA-437239 "Recycling pathway of L1" JAMg_model_1986.1 4 Reactome: R-HSA-975144;MetaCyc: PWY-7511;Reactome: R-HSA-937039;Reactome: R-HSA-9020702 "IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Protein ubiquitination";"IRAK1 recruits IKK complex";"Interleukin-1 signaling" JAMg_model_8453.2 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" JAMg_model_9194.4 6 MetaCyc: PWY-7234;KEGG: 00230+3.5.4.10+2.1.2.3;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.3;MetaCyc: PWY-6124;MetaCyc: PWY-6123 "Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I" JAMg_model_11572.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712 "Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport" JAMg_model_9615.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" JAMg_model_4976.4 7 MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7 "Sesamin biosynthesis";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis" JAMg_model_18902.2 3 KEGG: 00680+3.1.2.12;Reactome: R-HSA-156590;MetaCyc: PWY-1801 "Methane metabolism";"Glutathione conjugation";"Formaldehyde oxidation II (glutathione-dependent)" JAMg_model_3073.1 6 Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-9010553 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs" JAMg_model_3677.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" JAMg_model_9280.2 4 Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-3232142 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SUMOylation of ubiquitinylation proteins" JAMg_model_9515.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_21252.2 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" JAMg_model_14443.2 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" JAMg_model_4800.3 27 Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-168333 "Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery" JAMg_model_907.6 8 Reactome: R-HSA-190873;Reactome: R-HSA-432720;Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-196025 "Gap junction degradation";"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Formation of annular gap junctions" JAMg_model_6026.2 3 Reactome: R-HSA-202427;Reactome: R-HSA-6798695;Reactome: R-HSA-6807004 "Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation";"Negative regulation of MET activity" JAMg_model_9878.1 12 Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-1169408;Reactome: R-HSA-156827;Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-429947;Reactome: R-HSA-72662;Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ISG15 antiviral mechanism";"L13a-mediated translational silencing of Ceruloplasmin expression";"mTORC1-mediated signalling";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Deadenylation of mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" JAMg_model_13054.6 3 KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" JAMg_model_7052.3 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" JAMg_model_11737.4 1 Reactome: R-HSA-400253 "Circadian Clock" JAMg_model_18918.8 3 MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268 "Methylglyoxal degradation I";"Pyruvate metabolism";"Pyruvate metabolism" JAMg_model_7832.1 5 Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-5250924 "RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression" JAMg_model_17907.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" JAMg_model_20889.2 83 Reactome: R-HSA-391160;Reactome: R-HSA-388841;Reactome: R-HSA-5654726;Reactome: R-HSA-109704;Reactome: R-HSA-8853659;Reactome: R-HSA-1257604;Reactome: R-HSA-8865999;Reactome: R-HSA-2179392;Reactome: R-HSA-9027284;Reactome: R-HSA-179812;Reactome: R-HSA-5654695;Reactome: R-HSA-5654688;Reactome: R-HSA-1236382;Reactome: R-HSA-912526;Reactome: R-HSA-2871796;Reactome: R-HSA-8983432;Reactome: R-HSA-8856828;Reactome: R-HSA-354194;Reactome: R-HSA-167044;Reactome: R-HSA-512988;Reactome: R-HSA-9028731;Reactome: R-HSA-5654710;Reactome: R-HSA-5654712;Reactome: R-HSA-8851907;Reactome: R-HSA-5655253;Reactome: R-HSA-9634285;Reactome: R-HSA-9607240;Reactome: R-HSA-6811558;Reactome: R-HSA-2871809;Reactome: R-HSA-1963640;Reactome: R-HSA-5654733;Reactome: R-HSA-9664565;Reactome: R-HSA-9028335;Reactome: R-HSA-1250196;Reactome: R-HSA-182971;Reactome: R-HSA-5654689;Reactome: R-HSA-5655302;Reactome: R-HSA-1839117;Reactome: R-HSA-1963642;Reactome: R-HSA-74749;Reactome: R-HSA-983695;Reactome: R-HSA-8853334;Reactome: R-HSA-9034864;Reactome: R-HSA-8856825;Reactome: R-HSA-210993;Reactome: R-HSA-5654732;Reactome: R-HSA-8875656;Reactome: R-HSA-74751;Reactome: R-HSA-2424491;Reactome: R-HSA-5655291;Reactome: R-HSA-5654727;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-375165;Reactome: R-HSA-1433557;Reactome: R-HSA-5654699;Reactome: R-HSA-8875555;Reactome: R-HSA-912631;Reactome: R-HSA-8853338;Reactome: R-HSA-389359;Reactome: R-HSA-180336;Reactome: R-HSA-2219530;Reactome: R-HSA-1250347;Reactome: R-HSA-186763;Reactome: R-HSA-5654700;Reactome: R-HSA-9026519;Reactome: R-HSA-9645135;Reactome: R-HSA-5673001;Reactome: R-HSA-5637810;Reactome: R-HSA-5654720;Reactome: R-HSA-5663213;Reactome: R-HSA-1295596;Reactome: R-HSA-2730905;Reactome: R-HSA-5654706;Reactome: R-HSA-180292;Reactome: R-HSA-112412;Reactome: R-HSA-5654719;Reactome: R-HSA-2428933;Reactome: R-HSA-8851805;Reactome: R-HSA-5654704;Reactome: R-HSA-5654693;Reactome: R-HSA-1433559;Reactome: R-HSA-2029482 "Signal regulatory protein family interactions";"Costimulation by the CD28 family";"Negative regulation of FGFR1 signaling";"PI3K Cascade";"RET signaling";"PIP3 activates AKT signaling";"MET activates PTPN11";"EGFR Transactivation by Gastrin";"Erythropoietin activates RAS";"GRB2 events in EGFR signaling";"PI-3K cascade:FGFR2";"SHC-mediated cascade:FGFR1";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Interleukin receptor SHC signaling";"FCERI mediated MAPK activation";"Interleukin-15 signaling";"Clathrin-mediated endocytosis";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"Signalling to RAS";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Activated NTRK2 signals through FRS2 and FRS3";"PI-3K cascade:FGFR3";"FRS-mediated FGFR4 signaling";"MET activates PI3K/AKT signaling";"Signaling by FGFR2 in disease";"Constitutive Signaling by Overexpressed ERBB2";"FLT3 Signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"FCERI mediated Ca+2 mobilization";"GRB2 events in ERBB2 signaling";"Negative regulation of FGFR4 signaling";"Signaling by ERBB2 KD Mutants";"Activated NTRK2 signals through PI3K";"SHC1 events in ERBB2 signaling";"EGFR downregulation";"PI-3K cascade:FGFR1";"Signaling by FGFR1 in disease";"Signaling by cytosolic FGFR1 fusion mutants";"PI3K events in ERBB2 signaling";"Signal attenuation";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Signaling by FGFR3 fusions in cancer";"Activated NTRK3 signals through RAS";"Cargo recognition for clathrin-mediated endocytosis";"Tie2 Signaling";"Negative regulation of FGFR3 signaling";"MET receptor recycling";"Insulin receptor signalling cascade";"DAP12 signaling";"Signaling by FGFR4 in disease";"Negative regulation of FGFR2 signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"NCAM signaling for neurite out-growth";"Signaling by SCF-KIT";"SHC-mediated cascade:FGFR2";"MET activates RAP1 and RAC1";"Regulation of signaling by CBL";"Signaling by FGFR3 point mutants in cancer";"CD28 dependent Vav1 pathway";"SHC1 events in EGFR signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC1 events in ERBB4 signaling";"Downstream signal transduction";"FRS-mediated FGFR2 signaling";"Activated NTRK2 signals through RAS";"STAT5 Activation";"RAF/MAP kinase cascade";"Constitutive Signaling by EGFRvIII";"PI-3K cascade:FGFR4";"RHO GTPases Activate WASPs and WAVEs";"Spry regulation of FGF signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"FRS-mediated FGFR3 signaling";"GAB1 signalosome";"SOS-mediated signalling";"SHC-mediated cascade:FGFR4";"SHC-related events triggered by IGF1R";"MET activates RAS signaling";"SHC-mediated cascade:FGFR3";"FRS-mediated FGFR1 signaling";"Regulation of KIT signaling";"Regulation of actin dynamics for phagocytic cup formation" JAMg_model_13400.3 10 Reactome: R-HSA-202424;Reactome: R-HSA-5684264;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-2565942;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764 "Downstream TCR signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"Activation of NF-kappaB in B cells";"Neddylation";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling" JAMg_model_19254.1 10 Reactome: R-HSA-5609977;MetaCyc: PWY-7328;KEGG: 00520+5.1.3.2;Reactome: R-HSA-70370;MetaCyc: PWY-6397;MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6317;MetaCyc: PWY-7344 "Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Galactose catabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose detoxification";"Stachyose degradation";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"UDP-alpha-D-galactose biosynthesis" JAMg_model_20185.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_13857.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_6900.1 5 Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;Reactome: R-HSA-75105;Reactome: R-HSA-9029558 "ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis" JAMg_model_4905.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" JAMg_model_4567.1 7 KEGG: 00010+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-70268;KEGG: 00020+1.2.4.1;Reactome: R-HSA-389661;Reactome: R-HSA-5362517;Reactome: R-HSA-204174 "Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex" JAMg_model_9895.5 10 MetaCyc: PWY-6317;MetaCyc: PWY-7344;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-3821;MetaCyc: PWY-6397;Reactome: R-HSA-70370;MetaCyc: PWY-7328;KEGG: 00520+5.1.3.2;Reactome: R-HSA-5609977 "D-galactose degradation I (Leloir pathway)";"UDP-alpha-D-galactose biosynthesis";"Galactose metabolism";"Stachyose degradation";"D-galactose detoxification";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose catabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)" JAMg_model_7995.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" JAMg_model_8225.1 1 Reactome: R-HSA-400253 "Circadian Clock" JAMg_model_21022.5 13 Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs" JAMg_model_2446.6 5 Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-8943724 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription" JAMg_model_11950.1 15 Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-8936459 "Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" JAMg_model_20813.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" JAMg_model_17189.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" JAMg_model_19133.1 13 MetaCyc: PWY-6728;MetaCyc: PWY-7384;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5538;KEGG: 00720+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5537;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5913;MetaCyc: PWY-6969 "Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" JAMg_model_409.1 14 Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-5687128;Reactome: R-HSA-68877;Reactome: R-HSA-168333;Reactome: R-HSA-2467813;Reactome: R-HSA-9634638;Reactome: R-HSA-3769402;Reactome: R-HSA-69273;Reactome: R-HSA-450520;Reactome: R-HSA-9648025;Reactome: R-HSA-2173788;Reactome: R-HSA-165054;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MAPK6/MAPK4 signaling";"Mitotic Prometaphase";"NEP/NS2 Interacts with the Cellular Export Machinery";"Separation of Sister Chromatids";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Deactivation of the beta-catenin transactivating complex";"Cyclin A/B1/B2 associated events during G2/M transition";"HuR (ELAVL1) binds and stabilizes mRNA";"EML4 and NUDC in mitotic spindle formation";"Downregulation of TGF-beta receptor signaling";"Rev-mediated nuclear export of HIV RNA";"Resolution of Sister Chromatid Cohesion" JAMg_model_10788.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" JAMg_model_2640.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" JAMg_model_17226.1 2 Reactome: R-HSA-176187;Reactome: R-HSA-68962 "Activation of ATR in response to replication stress";"Activation of the pre-replicative complex" JAMg_model_2270.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" JAMg_model_6333.2 10 MetaCyc: PWY-5892;MetaCyc: PWY-5844;MetaCyc: PWY-5895;MetaCyc: PWY-7996;Reactome: R-HSA-2142789;MetaCyc: PWY-5891;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5890;MetaCyc: PWY-5849;MetaCyc: PWY-5839 "Menaquinol-12 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-4 biosynthesis I";"Ubiquinol biosynthesis";"Menaquinol-11 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-7 biosynthesis" JAMg_model_15872.1 5 Reactome: R-HSA-8951664;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827 "Neddylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" JAMg_model_3613.1 15 Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-9029569 "Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" JAMg_model_14756.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_20791.2 14 Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167200 "Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat" JAMg_model_1234.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" JAMg_model_15441.2 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" JAMg_model_18100.2 1 Reactome: R-HSA-1632852 "Macroautophagy" JAMg_model_19033.1 11 Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-380259;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-6807878;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497 "Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of Nlp from mitotic centrosomes";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"COPI-mediated anterograde transport";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" JAMg_model_11786.2 2 Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" JAMg_model_6261.1 1 Reactome: R-HSA-2467813 "Separation of Sister Chromatids" JAMg_model_15700.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" JAMg_model_6507.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" JAMg_model_19670.1 5 Reactome: R-HSA-68867;Reactome: R-HSA-69205;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68827 "Assembly of the pre-replicative complex";"G1/S-Specific Transcription";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex" JAMg_model_18245.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-6798695;Reactome: R-HSA-8873719;Reactome: R-HSA-1660499;Reactome: R-HSA-8876198 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Neutrophil degranulation";"RAB geranylgeranylation";"Synthesis of PIPs at the plasma membrane";"RAB GEFs exchange GTP for GDP on RABs" JAMg_model_3303.4 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" JAMg_model_17664.2 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" JAMg_model_2132.2 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" JAMg_model_1493.1 5 Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5689901;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565 "Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Metalloprotease DUBs";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" JAMg_model_21315.6 15 MetaCyc: PWY-2221;MetaCyc: PWY-6886;MetaCyc: PWY-8004;MetaCyc: PWY-5723;MetaCyc: PWY-6901;KEGG: 00010+2.7.1.40;MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-7383;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7218;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6142;Reactome: R-HSA-70171;MetaCyc: PWY-7003 "Entner-Doudoroff pathway III (semi-phosphorylative)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Rubisco shunt";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Purine metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Pyruvate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Glycerol degradation to butanol" JAMg_model_17801.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" JAMg_model_6544.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" JAMg_model_10992.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" JAMg_model_10031.1 5 KEGG: 00565+2.5.1.26;MetaCyc: PWY-7782;Reactome: R-HSA-9033500;Reactome: R-HSA-9033241;Reactome: R-HSA-75896 "Ether lipid metabolism";"Plasmalogen biosynthesis";"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import";"Plasmalogen biosynthesis" JAMg_model_15049.2 5 Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829 "Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" JAMg_model_18133.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_1988.4 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" JAMg_model_13130.1 21 KEGG: 00240+2.7.4.6;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7226;MetaCyc: PWY-7197;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7219;MetaCyc: PWY-7205;Reactome: R-HSA-499943;MetaCyc: PWY-6545;MetaCyc: PWY-7187;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7221;MetaCyc: PWY-7227;MetaCyc: PWY-7176;MetaCyc: PWY-7224;MetaCyc: PWY-7222 "Pyrimidine metabolism";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine ribonucleotides de novo biosynthesis";"CMP phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II" JAMg_model_14353.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" JAMg_model_775.1 1 Reactome: R-HSA-400253 "Circadian Clock" JAMg_model_20539.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" JAMg_model_9228.2 16 Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis" JAMg_model_799.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_12738.1 7 KEGG: 00562+3.1.3.25;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363;MetaCyc: PWY-4702 "Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phytate degradation I" JAMg_model_20190.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" JAMg_model_7796.1 15 Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-8936459 "Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" JAMg_model_7052.6 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" JAMg_model_13501.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706 "Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit" JAMg_model_18477.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" JAMg_model_3237.5 13 Reactome: R-HSA-167590;Reactome: R-HSA-2132295;Reactome: R-HSA-416993;Reactome: R-HSA-8866427;Reactome: R-HSA-182218;Reactome: R-HSA-3928665;Reactome: R-HSA-8964038;Reactome: R-HSA-5140745;Reactome: R-HSA-177504;Reactome: R-HSA-5099900;Reactome: R-HSA-437239;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Nef Mediated CD4 Down-regulation";"MHC class II antigen presentation";"Trafficking of GluR2-containing AMPA receptors";"VLDLR internalisation and degradation";"Nef Mediated CD8 Down-regulation";"EPH-ephrin mediated repulsion of cells";"LDL clearance";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Retrograde neurotrophin signalling";"WNT5A-dependent internalization of FZD4";"Recycling pathway of L1";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" JAMg_model_8994.1 4 MetaCyc: PWY-5030;Reactome: R-HSA-70921;MetaCyc: PWY-5028;KEGG: 00340+4.2.1.49 "L-histidine degradation III";"Histidine catabolism";"L-histidine degradation II";"Histidine metabolism" JAMg_model_11650.3 1 Reactome: R-HSA-71262 "Carnitine synthesis" JAMg_model_3313.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" JAMg_model_2584.2 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" JAMg_model_9797.4 1 Reactome: R-HSA-191273 "Cholesterol biosynthesis" JAMg_model_17419.2 12 Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-380284;Reactome: R-HSA-381038;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-6807878;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2132295 "Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of proteins required for interphase microtubule organization from the centrosome";"XBP1(S) activates chaperone genes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"COPI-mediated anterograde transport";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"MHC class II antigen presentation" JAMg_model_13412.1 4 KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49;MetaCyc: PWY-8004;MetaCyc: PWY-7268 "Glutathione metabolism";"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" JAMg_model_16589.2 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" JAMg_model_20787.14 32 Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-167172;Reactome: R-HSA-8851708;Reactome: R-HSA-77075;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-168325;Reactome: R-HSA-6807505;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-72203;Reactome: R-HSA-76042;Reactome: R-HSA-6803529;Reactome: R-HSA-9018519;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-73776 "mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"Transcription of the HIV genome";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Viral Messenger RNA Synthesis";"RNA polymerase II transcribes snRNA genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"FGFR2 alternative splicing";"Estrogen-dependent gene expression";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Promoter Escape" JAMg_model_20707.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection" JAMg_model_9985.3 4 Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257 "Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion" JAMg_model_13127.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-76042 "Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance" JAMg_model_14286.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" JAMg_model_20984.4 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-5576893 "Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Phase 2 - plateau phase" JAMg_model_17785.7 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" JAMg_model_9674.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" JAMg_model_19359.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_2822.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" JAMg_model_10246.4 13 MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2024101 "Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"CS/DS degradation" JAMg_model_18024.3 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" JAMg_model_16743.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" JAMg_model_19672.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" JAMg_model_16488.3 7 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" JAMg_model_16232.2 4 Reactome: R-HSA-156581;MetaCyc: PWY-5912;MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6 "Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis";"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" JAMg_model_10124.1 6 KEGG: 00290+4.2.1.33;Reactome: R-HSA-71403;KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3;Reactome: R-HSA-1268020;KEGG: 00720+4.2.1.3 "Valine, leucine and isoleucine biosynthesis";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Mitochondrial protein import";"Carbon fixation pathways in prokaryotes" JAMg_model_8013.2 6 Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation" JAMg_model_3499.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" JAMg_model_18574.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" JAMg_model_16943.1 4 Reactome: R-HSA-8950505;Reactome: R-HSA-1268020;Reactome: R-HSA-3371453;Reactome: R-HSA-8949613 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Mitochondrial protein import";"Regulation of HSF1-mediated heat shock response";"Cristae formation" JAMg_model_15626.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" JAMg_model_12757.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" JAMg_model_9142.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" JAMg_model_7078.1 14 Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-2022377;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012 "L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Viral mRNA Translation";"Peptide chain elongation";"Metabolism of Angiotensinogen to Angiotensins";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency" JAMg_model_8298.11 4 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-1912420 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi" JAMg_model_6221.2 18 Reactome: R-HSA-975956;Reactome: R-HSA-6790901;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"mTORC1-mediated signalling";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Peptide chain elongation";"Viral mRNA Translation" JAMg_model_11562.2 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" JAMg_model_3095.1 1 Reactome: R-HSA-211981 "Xenobiotics" JAMg_model_8547.1 5 Reactome: R-HSA-450604;Reactome: R-HSA-430039;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513 "KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" JAMg_model_4609.1 15 MetaCyc: PWY-2221;MetaCyc: PWY-6886;MetaCyc: PWY-8004;MetaCyc: PWY-5723;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-7383;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7218;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6142;Reactome: R-HSA-70171;MetaCyc: PWY-7003 "Entner-Doudoroff pathway III (semi-phosphorylative)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Purine metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Pyruvate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Glycerol degradation to butanol" JAMg_model_359.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" JAMg_model_14404.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_5023.1 57 Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785 "Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome" JAMg_model_10017.3 1 Reactome: R-HSA-8874211 "CREB3 factors activate genes" JAMg_model_4219.3 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" JAMg_model_8784.1 3 Reactome: R-HSA-164843;Reactome: R-HSA-3108214;Reactome: R-HSA-5693571 "2-LTR circle formation";"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)" JAMg_model_17201.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" JAMg_model_18327.2 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" JAMg_model_12913.1 5 Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-389357 "VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling" JAMg_model_12720.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" JAMg_model_11644.2 16 Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553 "Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Viral mRNA Translation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs" JAMg_model_17061.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" JAMg_model_822.1 1 Reactome: R-HSA-211981 "Xenobiotics" JAMg_model_5802.1 5 Reactome: R-HSA-9029558;Reactome: R-HSA-2426168;Reactome: R-HSA-75105;Reactome: R-HSA-163765;Reactome: R-HSA-199220 "NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis";"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism" JAMg_model_5220.2 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" JAMg_model_731.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_2885.3 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" JAMg_model_8875.3 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_340.3 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" JAMg_model_16752.1 2 Reactome: R-HSA-3108214;Reactome: R-HSA-5685938 "SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)" JAMg_model_17664.3 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" JAMg_model_10636.1 1 Reactome: R-HSA-977606 "Regulation of Complement cascade" JAMg_model_18315.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_14287.2 11 Reactome: R-HSA-69166;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-174437;Reactome: R-HSA-69473;Reactome: R-HSA-5693616 "Removal of the Flap Intermediate";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate from the C-strand";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange" JAMg_model_18437.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" JAMg_model_14657.4 4 Reactome: R-HSA-3371497;Reactome: R-HSA-8939211;Reactome: R-HSA-3371568;Reactome: R-HSA-9018519 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"ESR-mediated signaling";"Attenuation phase";"Estrogen-dependent gene expression" JAMg_model_2796.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" JAMg_model_8550.4 14 MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation" JAMg_model_12040.1 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" JAMg_model_8706.1 1 Reactome: R-HSA-6793080 "rRNA modification in the mitochondrion" JAMg_model_8833.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_7014.4 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_2053.2 2 Reactome: R-HSA-71384;KEGG: 00030+1.1.1.47 "Ethanol oxidation";"Pentose phosphate pathway" JAMg_model_20334.6 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" JAMg_model_10230.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" JAMg_model_11022.1 1 Reactome: R-HSA-3000171 "Non-integrin membrane-ECM interactions" JAMg_model_2148.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-444821 "G alpha (s) signalling events";"Relaxin receptors" JAMg_model_7890.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" JAMg_model_8268.2 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" JAMg_model_9600.2 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6811434 "Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_10003.2 9 KEGG: 04070+3.1.4.11;Reactome: R-HSA-112043;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6351;MetaCyc: PWY-8052;Reactome: R-HSA-416476 "Phosphatidylinositol signaling system";"PLC beta mediated events";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events" JAMg_model_7900.3 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" JAMg_model_10797.2 1 Reactome: R-HSA-5676934 "Protein repair" JAMg_model_359.7 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" JAMg_model_14381.1 10 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1839117;Reactome: R-HSA-5655302;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Rho GTPase cycle";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease";"Human immunodeficiency virus 1 infection" JAMg_model_12716.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" JAMg_model_12229.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_21247.1 4 Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Neutrophil degranulation";"MHC class II antigen presentation";"Cargo concentration in the ER";"COPII-mediated vesicle transport" JAMg_model_5030.4 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" JAMg_model_15390.2 33 Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-68877;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-4085377 "EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Mitotic Prometaphase";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of SUMOylation proteins" JAMg_model_2603.1 10 MetaCyc: PWY-7385;KEGG: 00052+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00680+2.7.1.11;KEGG: 00051+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00030+2.7.1.11 "1,3-propanediol biosynthesis (engineered)";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Methane metabolism";"Fructose and mannose metabolism";"Glycolysis";"Pentose phosphate pathway" JAMg_model_13295.1 5 Reactome: R-HSA-5687128;KEGG: 05235+3.1.3.16;Reactome: R-HSA-176407;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "MAPK6/MAPK4 signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" JAMg_model_5978.2 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" JAMg_model_4960.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" JAMg_model_2046.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" JAMg_model_2166.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983168 "Nuclear Receptor transcription pathway";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_16501.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" JAMg_model_18910.6 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" JAMg_model_2711.1 26 Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-389960;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467 "Mitotic Prometaphase";"HCMV Early Events";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"Formation of tubulin folding intermediates by CCT/TriC";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"Aggrephagy";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs" JAMg_model_21283.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" JAMg_model_9226.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" JAMg_model_7144.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" JAMg_model_10218.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" JAMg_model_7362.3 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_3237.4 13 Reactome: R-HSA-416993;Reactome: R-HSA-8866427;Reactome: R-HSA-2132295;Reactome: R-HSA-167590;Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-177504;Reactome: R-HSA-8964038;Reactome: R-HSA-3928665;Reactome: R-HSA-182218;Reactome: R-HSA-8856825;Reactome: R-HSA-437239;Reactome: R-HSA-8856828 "Trafficking of GluR2-containing AMPA receptors";"VLDLR internalisation and degradation";"MHC class II antigen presentation";"Nef Mediated CD4 Down-regulation";"WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Retrograde neurotrophin signalling";"LDL clearance";"EPH-ephrin mediated repulsion of cells";"Nef Mediated CD8 Down-regulation";"Cargo recognition for clathrin-mediated endocytosis";"Recycling pathway of L1";"Clathrin-mediated endocytosis" JAMg_model_6886.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" JAMg_model_8112.2 2 KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10 "Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis" JAMg_model_9797.5 14 Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-191273;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827 "Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Cholesterol biosynthesis";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression" JAMg_model_1758.2 6 Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390471 "Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis" JAMg_model_13054.9 3 KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" JAMg_model_14533.1 13 MetaCyc: PWY-7254;KEGG: 00020+4.2.1.2;MetaCyc: PWY-5913;MetaCyc: PWY-6969;MetaCyc: PWY-8086;MetaCyc: PWY-5392;KEGG: 00720+4.2.1.2;Reactome: R-HSA-71403;MetaCyc: PWY-5690;KEGG: 00620+4.2.1.2;MetaCyc: PWY-6728;MetaCyc: PWY-7384;MetaCyc: PWY-561 "TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Pyruvate metabolism";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Superpathway of glyoxylate cycle and fatty acid degradation" JAMg_model_4424.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-6798695 "Glycosphingolipid metabolism";"Neutrophil degranulation" JAMg_model_20988.4 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" JAMg_model_14802.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" JAMg_model_20988.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" JAMg_model_12379.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" JAMg_model_13483.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Viral mRNA Translation" JAMg_model_14445.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" JAMg_model_4541.13 7 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2" JAMg_model_9186.4 6 MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism" JAMg_model_9782.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" JAMg_model_8920.1 7 Reactome: R-HSA-351202;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.22;KEGG: 00480+2.5.1.16;KEGG: 00480+2.5.1.22;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16 "Metabolism of polyamines";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism" JAMg_model_12236.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2 "VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway" JAMg_model_12772.4 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" JAMg_model_13165.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012 "L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency" JAMg_model_19648.2 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" JAMg_model_10598.6 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5689880 "UCH proteinases";"Ub-specific processing proteases" JAMg_model_7046.2 4 KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219 "Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis" JAMg_model_17704.1 6 Reactome: R-HSA-6798695;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "Neutrophil degranulation";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling" JAMg_model_15725.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" JAMg_model_8698.6 22 MetaCyc: PWY-5080;MetaCyc: PWY-7049;MetaCyc: PWY-7602;MetaCyc: PWY-6433;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7053;MetaCyc: PWY-5353;MetaCyc: PWY-7606;MetaCyc: PWY-6958;MetaCyc: PWY-7035;MetaCyc: PWY-7726;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7727;MetaCyc: PWY-7592;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7728;MetaCyc: PWY-8041 "Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"(9Z)-tricosene biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Ultra-long-chain fatty acid biosynthesis" JAMg_model_9280.1 4 Reactome: R-HSA-3232142;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "SUMOylation of ubiquitinylation proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" JAMg_model_2408.2 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_17134.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" JAMg_model_19198.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-8869496 "rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" JAMg_model_11705.1 6 MetaCyc: PWY-7234;KEGG: 00230+4.1.1.21;Reactome: R-HSA-73817;MetaCyc: PWY-6124;KEGG: 00230+6.3.2.6;MetaCyc: PWY-6123 "Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I" JAMg_model_21145.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" JAMg_model_20077.1 5 KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928;MetaCyc: PWY-6558;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253 "Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS" JAMg_model_16195.3 56 Reactome: R-HSA-5687128;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-350562;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870 "MAPK6/MAPK4 signaling";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of ornithine decarboxylase (ODC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"UCH proteinases";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins" JAMg_model_11316.1 26 Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-389960;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-68877;Reactome: R-HSA-9609690 "RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"Formation of tubulin folding intermediates by CCT/TriC";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"Mitotic Prometaphase";"HCMV Early Events" JAMg_model_20392.3 4 Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-110312 "Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Translesion synthesis by REV1" JAMg_model_4046.4 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" JAMg_model_2312.2 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" JAMg_model_20123.2 8 Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-4551638;Reactome: R-HSA-3214841;Reactome: R-HSA-2559580;Reactome: R-HSA-8953750;Reactome: R-HSA-5617472;Reactome: R-HSA-8943724 "HCMV Early Events";"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins";"PKMTs methylate histone lysines";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by E2F6";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of PTEN gene transcription" JAMg_model_2338.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-1236974 "SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway" JAMg_model_20948.1 24 Reactome: R-HSA-416482;Reactome: R-HSA-400042;Reactome: R-HSA-420092;Reactome: R-HSA-418597;Reactome: R-HSA-8964616;Reactome: R-HSA-8964315;Reactome: R-HSA-416476;Reactome: R-HSA-6814122;Reactome: R-HSA-392451;Reactome: R-HSA-418555;Reactome: R-HSA-500657;Reactome: R-HSA-202040;Reactome: R-HSA-392170;Reactome: R-HSA-4086398;Reactome: R-HSA-392851;Reactome: R-HSA-9009391;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-428930;Reactome: R-HSA-381676;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-418217 "G alpha (12/13) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-type ligand receptors";"G alpha (z) signalling events";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through BTK";"G alpha (q) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through PI3Kgamma";"G alpha (s) signalling events";"Presynaptic function of Kainate receptors";"G-protein activation";"ADP signalling through P2Y purinoceptor 12";"Ca2+ pathway";"Prostacyclin signalling through prostacyclin receptor";"Extra-nuclear estrogen signaling";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thromboxane signalling through TP receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through PLC beta" JAMg_model_17987.2 10 Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-3214847;Reactome: R-HSA-73779;Reactome: R-HSA-76042 "RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"HATs acetylate histones";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance" JAMg_model_4185.7 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" JAMg_model_17530.1 4 Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554 "Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" JAMg_model_11340.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_10123.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" JAMg_model_11629.1 2 Reactome: R-HSA-5635838;Reactome: R-HSA-5632681 "Activation of SMO";"Ligand-receptor interactions" JAMg_model_3936.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" JAMg_model_17785.5 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" JAMg_model_14337.1 5 Reactome: R-HSA-2206305;Reactome: R-HSA-2022857;Reactome: R-HSA-432720;Reactome: R-HSA-6798695;KEGG: 00531+3.1.6.14 "MPS IIID - Sanfilippo syndrome D";"Keratan sulfate degradation";"Lysosome Vesicle Biogenesis";"Neutrophil degranulation";"Glycosaminoglycan degradation" JAMg_model_11775.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" JAMg_model_11845.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" JAMg_model_13980.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" JAMg_model_18864.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-174490 "Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"HCMV Late Events";"Membrane binding and targetting of GAG proteins" JAMg_model_957.7 4 Reactome: R-HSA-6811434;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1";"MHC class II antigen presentation";"Kinesins" JAMg_model_361.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" JAMg_model_6354.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" JAMg_model_4116.4 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" JAMg_model_9222.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_21183.2 6 KEGG: 00520+1.1.1.22;KEGG: 00040+1.1.1.22;KEGG: 00053+1.1.1.22;MetaCyc: PWY-7346;Reactome: R-HSA-173599;MetaCyc: PWY-7820 "Amino sugar and nucleotide sugar metabolism";"Pentose and glucuronate interconversions";"Ascorbate and aldarate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Formation of the active cofactor, UDP-glucuronate";"Teichuronic acid biosynthesis (B. subtilis 168)" JAMg_model_15612.2 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" JAMg_model_13433.3 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_19568.1 3 Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968 "Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6" JAMg_model_12161.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" JAMg_model_18930.1 17 Reactome: R-HSA-5693548;Reactome: R-HSA-1834949;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5685939;Reactome: R-HSA-5693568;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579 "Sensing of DNA Double Strand Breaks";"Cytosolic sensors of pathogen-associated DNA";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through MMEJ (alt-NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange" JAMg_model_156.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_1944.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" JAMg_model_9932.6 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_16456.2 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" JAMg_model_12480.1 11 MetaCyc: PWY-922;MetaCyc: PWY-6859;MetaCyc: PWY-7102;Reactome: R-HSA-191273;MetaCyc: PWY-6174;MetaCyc: PWY-5123;MetaCyc: PWY-7560;KEGG: 00900+5.3.3.2;MetaCyc: PWY-7391;MetaCyc: PWY-7524;MetaCyc: PWY-6383 "Mevalonate pathway I";"All-trans-farnesol biosynthesis";"Bisabolene biosynthesis (engineered)";"Cholesterol biosynthesis";"Mevalonate pathway II (archaea)";"Trans, trans-farnesyl diphosphate biosynthesis";"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis" JAMg_model_10263.3 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" JAMg_model_17943.2 5 Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-5625740 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs" JAMg_model_10106.1 3 KEGG: 00480+4.3.2.9;Reactome: R-HSA-174403;MetaCyc: PWY-4041 "Glutathione metabolism";"Glutathione synthesis and recycling";"Gamma-glutamyl cycle" JAMg_model_14261.1 3 MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757 "Folate polyglutamylation";"Folate biosynthesis";"Metabolism of folate and pterines" JAMg_model_8501.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" JAMg_model_16099.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" JAMg_model_18133.5 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_17664.5 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" JAMg_model_13539.1 7 Reactome: R-HSA-5625886;Reactome: R-HSA-983231;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-9029569;Reactome: R-HSA-3214842;Reactome: R-HSA-9018519 "Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Factors involved in megakaryocyte development and platelet production";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDMs demethylate histones";"Estrogen-dependent gene expression" JAMg_model_15875.4 1 Reactome: R-HSA-8949613 "Cristae formation" JAMg_model_16886.4 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" JAMg_model_7513.1 7 MetaCyc: PWY-6470;KEGG: 00510+2.7.8.15;Reactome: R-HSA-4549356;Reactome: R-HSA-446193;MetaCyc: PWY-6471;MetaCyc: PWY-5265;KEGG: 00550+2.7.8.13 "Peptidoglycan biosynthesis V (beta-lactam resistance)";"N-Glycan biosynthesis";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis" JAMg_model_4808.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-8949215 "Ub-specific processing proteases";"Mitochondrial calcium ion transport" JAMg_model_20039.1 56 Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-350562;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-1236978;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-180534 "Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"Orc1 removal from chromatin";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Regulation of ornithine decarboxylase (ODC)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4" JAMg_model_20843.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" JAMg_model_17759.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-5205685 "Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy" JAMg_model_11168.1 4 Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497 "COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" JAMg_model_21322.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-6791226 "Peptide chain elongation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_2961.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" JAMg_model_17619.2 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" JAMg_model_15974.2 10 Reactome: R-HSA-70263;MetaCyc: PWY-8004;MetaCyc: PWY-6886;KEGG: 00010+2.7.2.3;MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-6901;KEGG: 00710+2.7.2.3;MetaCyc: PWY-7003;Reactome: R-HSA-70171 "Gluconeogenesis";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Glycolysis" JAMg_model_1476.1 10 MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-7559;MetaCyc: PWY-6842;MetaCyc: PWY-4041;MetaCyc: PWY-7112 "Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Glutathione metabolism";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification" JAMg_model_4462.1 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" JAMg_model_1565.3 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" JAMg_model_20621.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" JAMg_model_19253.1 16 Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-9010553;Reactome: R-HSA-167238;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-674695;Reactome: R-HSA-8951664;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-983168;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167290 "Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of expression of SLITs and ROBOs";"Pausing and recovery of Tat-mediated HIV elongation";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RNA Polymerase II Pre-transcription Events";"Neddylation";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation" JAMg_model_19299.2 24 Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-5617833 "Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"HCMV Early Events";"Mitotic Prometaphase";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Kinesins";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly" JAMg_model_19874.3 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_8124.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" JAMg_model_11694.1 11 Reactome: R-HSA-5685938;Reactome: R-HSA-525793;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-428890;Reactome: R-HSA-983231;Reactome: R-HSA-5693565;KEGG: 04660+2.7.10.2;Reactome: R-HSA-69231;Reactome: R-HSA-8939236;Reactome: R-HSA-8940973 "HDR through Single Strand Annealing (SSA)";"Myogenesis";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Role of ABL in ROBO-SLIT signaling";"Factors involved in megakaryocyte development and platelet production";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"T cell receptor signaling pathway";"Cyclin D associated events in G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX2 regulates osteoblast differentiation" JAMg_model_1575.2 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" JAMg_model_8081.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450513 "KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" JAMg_model_616.1 1 Reactome: R-HSA-70171 "Glycolysis" JAMg_model_9563.1 5 Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390450 "Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC" JAMg_model_8162.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912 "Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane" JAMg_model_17832.1 58 Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-5689901;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-1169091;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684 "Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Metalloprotease DUBs";"Degradation of DVL";"FCERI mediated NF-kB activation";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"Activation of NF-kappaB in B cells";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"Orc1 removal from chromatin";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state" JAMg_model_18188.5 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" JAMg_model_10638.2 16 Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156827 "Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression" JAMg_model_8160.1 12 Reactome: R-HSA-70171;MetaCyc: PWY-6142;MetaCyc: PWY-1861;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00710+4.1.2.13;KEGG: 00680+4.1.2.13;KEGG: 00030+4.1.2.13;KEGG: 00051+4.1.2.13;MetaCyc: PWY-7385 "Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Pentose phosphate pathway";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)" JAMg_model_10840.2 11 Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-174430;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-68952;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-68962;Reactome: R-HSA-5696397 "Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Telomere C-strand synthesis initiation";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"DNA replication initiation";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in GG-NER" JAMg_model_513.1 8 Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-6798695;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380270 "AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Neutrophil degranulation";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes" JAMg_model_6775.1 14 MetaCyc: PWY-7187;Reactome: R-HSA-74217;KEGG: 00760+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.9;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7206;MetaCyc: PWY-7821;KEGG: 00240+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00230+2.7.1.20;KEGG: 00770+3.6.1.9;MetaCyc: PWY-6619 "Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine salvage";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Tunicamycin biosynthesis";"Pyrimidine metabolism";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pantothenate and CoA biosynthesis";"Adenine and adenosine salvage VI" JAMg_model_10212.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" JAMg_model_3570.1 1 Reactome: R-HSA-211981 "Xenobiotics" JAMg_model_1998.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_7052.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" JAMg_model_20991.1 10 KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-983189;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6811434 "PI3K-Akt signaling pathway";"mTOR signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Kinesins";"Human immunodeficiency virus 1 infection";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_17580.2 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" JAMg_model_17071.1 44 Reactome: R-HSA-1295596;Reactome: R-HSA-5663213;Reactome: R-HSA-445144;Reactome: R-HSA-5674135;Reactome: R-HSA-5673001;Reactome: R-HSA-6811558;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-2029482;Reactome: R-HSA-444257;Reactome: R-HSA-170968;Reactome: R-HSA-198753;Reactome: R-HSA-74749;Reactome: R-HSA-881907;Reactome: R-HSA-982772;Reactome: R-HSA-9634638;Reactome: R-HSA-9635465;Reactome: R-HSA-8943724;Reactome: R-HSA-5654733;Reactome: R-HSA-2559585;Reactome: R-HSA-6802948;KEGG: 04150+2.7.11.24;Reactome: R-HSA-5654727;Reactome: R-HSA-162658;Reactome: R-HSA-9627069;Reactome: R-HSA-9649948;Reactome: R-HSA-5654726;Reactome: R-HSA-6802952;Reactome: R-HSA-8940973;Reactome: R-HSA-2559582;Reactome: R-HSA-5654732;Reactome: R-HSA-456926;Reactome: R-HSA-450341;Reactome: R-HSA-5668599;Reactome: R-HSA-879415;Reactome: R-HSA-8939211;Reactome: R-HSA-2559580;Reactome: R-HSA-3371453;Reactome: R-HSA-5675221;Reactome: R-HSA-2871796;Reactome: R-HSA-202670;Reactome: R-HSA-5674499;Reactome: R-HSA-112409;Reactome: R-HSA-375165 "Spry regulation of FGF signaling";"RHO GTPases Activate WASPs and WAVEs";"Signal transduction by L1";"MAP2K and MAPK activation";"RAF/MAP kinase cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Regulation of actin dynamics for phagocytic cup formation";"RSK activation";"Frs2-mediated activation";"ERK/MAPK targets";"Signal attenuation";"Gastrin-CREB signalling pathway via PKC and MAPK";"Growth hormone receptor signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Suppression of apoptosis";"Regulation of PTEN gene transcription";"Negative regulation of FGFR4 signaling";"Oncogene Induced Senescence";"Signaling by high-kinase activity BRAF mutants";"mTOR signaling pathway";"Negative regulation of FGFR2 signaling";"Golgi Cisternae Pericentriolar Stack Reorganization";"Regulation of the apoptosome activity";"Signaling downstream of RAS mutants";"Negative regulation of FGFR1 signaling";"Signaling by BRAF and RAF fusions";"RUNX2 regulates osteoblast differentiation";"Senescence-Associated Secretory Phenotype (SASP)";"Negative regulation of FGFR3 signaling";"Thrombin signalling through proteinase activated receptors (PARs)";"Activation of the AP-1 family of transcription factors";"RHO GTPases Activate NADPH Oxidases";"Advanced glycosylation endproduct receptor signaling";"ESR-mediated signaling";"Oxidative Stress Induced Senescence";"Regulation of HSF1-mediated heat shock response";"Negative regulation of MAPK pathway";"FCERI mediated MAPK activation";"ERKs are inactivated";"Negative feedback regulation of MAPK pathway";"RAF-independent MAPK1/3 activation";"NCAM signaling for neurite out-growth" JAMg_model_2764.2 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" JAMg_model_18834.2 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" JAMg_model_12502.1 3 Reactome: R-HSA-5173105;MetaCyc: PWY-7979;KEGG: 00515+2.7.1.183 "O-linked glycosylation";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis" JAMg_model_17849.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_11500.2 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" JAMg_model_16474.2 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" JAMg_model_13907.1 5 Reactome: R-HSA-6811438;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-204005 "Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport" JAMg_model_8507.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" JAMg_model_9417.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_18044.1 5 Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-532668;Reactome: R-HSA-879415;Reactome: R-HSA-901042 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Advanced glycosylation endproduct receptor signaling";"Calnexin/calreticulin cycle" JAMg_model_19199.4 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" JAMg_model_14925.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" JAMg_model_3218.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-901032 "Protein ubiquitination";"ER Quality Control Compartment (ERQC)" JAMg_model_9642.2 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_8940.4 5 KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895;Reactome: R-HSA-9633012;Reactome: R-HSA-8963693;Reactome: R-HSA-380994 "Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Aspartate and asparagine metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress" JAMg_model_2759.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" JAMg_model_17486.3 2 Reactome: R-HSA-1362409;Reactome: R-HSA-1268020 "Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import" JAMg_model_19491.3 4 Reactome: R-HSA-1362409;Reactome: R-HSA-947581;MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7 "Mitochondrial iron-sulfur cluster biogenesis";"Molybdenum cofactor biosynthesis";"[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism" JAMg_model_13054.1 3 KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" JAMg_model_860.2 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" JAMg_model_1341.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" JAMg_model_20787.9 32 Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-168325;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-167238;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-6803529;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-72203;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-167162;Reactome: R-HSA-167158;Reactome: R-HSA-113418 "Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Viral Messenger RNA Synthesis";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"RNA Polymerase II HIV Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex" JAMg_model_8702.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" JAMg_model_19983.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_579.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_6954.1 7 Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-5617472;Reactome: R-HSA-8953750;Reactome: R-HSA-2559580;Reactome: R-HSA-3214841;Reactome: R-HSA-8943724 "PRC2 methylates histones and DNA";"HCMV Early Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional Regulation by E2F6";"Oxidative Stress Induced Senescence";"PKMTs methylate histone lysines";"Regulation of PTEN gene transcription" JAMg_model_7210.1 5 Reactome: R-HSA-196741;Reactome: R-HSA-3359469;Reactome: R-HSA-1614635;Reactome: R-HSA-156581;Reactome: R-HSA-3359467 "Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MTR causes methylmalonic aciduria and homocystinuria type cblG";"Sulfur amino acid metabolism";"Methylation";"Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE" JAMg_model_10232.1 3 Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-5632968 "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6" JAMg_model_13339.4 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" JAMg_model_11305.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" JAMg_model_12310.1 9 Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-69017;Reactome: R-HSA-176187 "Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"CDK-mediated phosphorylation and removal of Cdc6";"Activation of ATR in response to replication stress" JAMg_model_10270.1 10 Reactome: R-HSA-209560;MetaCyc: PWY-3341;Reactome: R-HSA-209543;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2;Reactome: R-HSA-9020702;MetaCyc: PWY-6344;Reactome: R-HSA-5205685;Reactome: R-HSA-205043 "NF-kB is activated and signals survival";"L-proline biosynthesis III (from L-ornithine)";"p75NTR recruits signalling complexes";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"Interleukin-1 signaling";"L-ornithine degradation II (Stickland reaction)";"Pink/Parkin Mediated Mitophagy";"NRIF signals cell death from the nucleus" JAMg_model_7144.2 1 Reactome: R-HSA-71262 "Carnitine synthesis" JAMg_model_7801.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" JAMg_model_322.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" JAMg_model_16633.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" JAMg_model_13433.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_11562.3 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" JAMg_model_13732.1 15 Reactome: R-HSA-9029569;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX" JAMg_model_14518.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" JAMg_model_19431.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Peptide chain elongation" JAMg_model_17137.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" JAMg_model_615.1 5 Reactome: R-HSA-5689877;Reactome: R-HSA-983168;Reactome: R-HSA-977225;Reactome: R-HSA-5205685;Reactome: R-HSA-9646399 "Josephin domain DUBs";"Antigen processing: Ubiquitination & Proteasome degradation";"Amyloid fiber formation";"Pink/Parkin Mediated Mitophagy";"Aggrephagy" JAMg_model_18264.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" JAMg_model_7998.2 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" JAMg_model_12459.2 16 Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557 "Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis" JAMg_model_6324.4 10 KEGG: 00561+2.3.1.15;KEGG: 00564+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-5667;MetaCyc: PWY-8053 "Glycerolipid metabolism";"Glycerophospholipid metabolism";"Synthesis of PA";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II" JAMg_model_3454.1 3 KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619 "Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI" JAMg_model_10058.1 2 Reactome: R-HSA-6785470;Reactome: R-HSA-6784531 "tRNA processing in the mitochondrion";"tRNA processing in the nucleus" JAMg_model_16071.5 9 Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-114608;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946 "Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Platelet degranulation";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants" JAMg_model_16396.2 56 Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978 "Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FCERI mediated NF-kB activation";"UCH proteinases";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"Orc1 removal from chromatin";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)" JAMg_model_12117.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" JAMg_model_6589.5 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" JAMg_model_7186.4 18 MetaCyc: PWY-7383;MetaCyc: PWY-6643;KEGG: 00401+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00250+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-7115;MetaCyc: PWY-6638;KEGG: 00220+2.6.1.1;KEGG: 00360+2.6.1.1 "Anaerobic energy metabolism (invertebrates, cytosol)";"Coenzyme M biosynthesis II";"Novobiocin biosynthesis";"Cysteine and methionine metabolism";"Partial TCA cycle (obligate autotrophs)";"Alanine, aspartate and glutamate metabolism";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"Arginine and proline metabolism";"Carbon fixation in photosynthetic organisms";"Phenylalanine, tyrosine and tryptophan biosynthesis";"(R)-cysteate degradation";"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Sulfolactate degradation III";"Arginine biosynthesis";"Phenylalanine metabolism" JAMg_model_6599.4 1 Reactome: R-HSA-189200 "Cellular hexose transport" JAMg_model_3264.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" JAMg_model_18336.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" JAMg_model_6026.1 3 Reactome: R-HSA-202427;Reactome: R-HSA-6798695;Reactome: R-HSA-6807004 "Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation";"Negative regulation of MET activity" JAMg_model_11147.1 4 MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14 "Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism" JAMg_model_13054.7 3 MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism" JAMg_model_6424.2 27 Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-77588;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-159230;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-72165;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-8851708;Reactome: R-HSA-111367;Reactome: R-HSA-159227;Reactome: R-HSA-975957;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-975956;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-72203;Reactome: R-HSA-159236;Reactome: R-HSA-6803529;Reactome: R-HSA-9010553 "snRNP Assembly";"mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transport of the SLBP Dependant Mature mRNA";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Minor Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Signaling by FGFR2 IIIa TM";"SLBP independent Processing of Histone Pre-mRNAs";"Transport of the SLBP independent Mature mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"Processing of Capped Intron-Containing Pre-mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"FGFR2 alternative splicing";"Regulation of expression of SLITs and ROBOs" JAMg_model_4341.1 56 Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-75815;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-1236978;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-350562;Reactome: R-HSA-69481;Reactome: R-HSA-382556 "Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of ornithine decarboxylase (ODC)";"G2/M Checkpoints";"ABC-family proteins mediated transport" JAMg_model_4058.1 2 Reactome: R-HSA-2142700;Reactome: R-HSA-2142691 "Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" JAMg_model_5776.7 3 Reactome: R-HSA-1614603;Reactome: R-HSA-2408508;Reactome: R-HSA-1614558 "Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine" JAMg_model_17619.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" JAMg_model_3319.2 22 KEGG: 00350+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6642;Reactome: R-HSA-72163;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-7115;MetaCyc: PWY-6638;KEGG: 00360+2.6.1.1;KEGG: 00220+2.6.1.1;Reactome: R-HSA-73856;MetaCyc: PWY-7383;MetaCyc: PWY-6643;Reactome: R-HSA-72187;KEGG: 00401+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00270+2.6.1.1;KEGG: 00250+2.6.1.1;Reactome: R-HSA-159236 "Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Arginine and proline metabolism";"Carbon fixation in photosynthetic organisms";"(R)-cysteate degradation";"mRNA Splicing - Major Pathway";"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Sulfolactate degradation III";"Phenylalanine metabolism";"Arginine biosynthesis";"RNA Polymerase II Transcription Termination";"Anaerobic energy metabolism (invertebrates, cytosol)";"Coenzyme M biosynthesis II";"mRNA 3'-end processing";"Novobiocin biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Cysteine and methionine metabolism";"Alanine, aspartate and glutamate metabolism";"Transport of Mature mRNA derived from an Intron-Containing Transcript" JAMg_model_8083.1 12 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-6804756;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167287 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery" JAMg_model_10824.1 12 KEGG: 00230+2.7.1.25;KEGG: 00920+2.7.7.4;MetaCyc: PWY-5278;KEGG: 00450+2.7.7.4;Reactome: R-HSA-174362;Reactome: R-HSA-2408550;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5340;MetaCyc: PWY-6683;KEGG: 00920+2.7.1.25;KEGG: 00230+2.7.7.4;MetaCyc: PWY-6932 "Purine metabolism";"Sulfur metabolism";"Sulfite oxidation III";"Selenocompound metabolism";"Transport and synthesis of PAPS";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Monobactam biosynthesis";"Sulfate activation for sulfonation";"Assimilatory sulfate reduction III";"Sulfur metabolism";"Purine metabolism";"Selenate reduction" JAMg_model_1776.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" JAMg_model_12537.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_12919.3 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_6601.5 1 Reactome: R-HSA-189200 "Cellular hexose transport" JAMg_model_3999.1 2 Reactome: R-HSA-3065676;Reactome: R-HSA-3065678 "SUMO is conjugated to E1 (UBA2:SAE1)";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)" JAMg_model_13521.2 8 Reactome: R-HSA-180024;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-381676;Reactome: R-HSA-164378;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-432040 "DARPP-32 events";"Hedgehog 'off' state";"PKA activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Vasopressin regulates renal water homeostasis via Aquaporins" JAMg_model_12887.3 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" JAMg_model_20524.2 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" JAMg_model_2764.6 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" JAMg_model_9921.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_2017.5 5 Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264;MetaCyc: PWY-5381;Reactome: R-HSA-1368108 "Neutrophil degranulation";"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" JAMg_model_17734.7 5 Reactome: R-HSA-189451;MetaCyc: PWY-5189;Reactome: R-HSA-6798695;MetaCyc: PWY-5188;KEGG: 00860+4.2.1.24 "Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Neutrophil degranulation";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism" JAMg_model_6938.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_13537.1 5 Reactome: R-HSA-6798695;MetaCyc: PWY-7282;Reactome: R-HSA-964975;KEGG: 00750+2.7.1.35;MetaCyc: PWY-7204 "Neutrophil degranulation";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)" JAMg_model_18156.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" JAMg_model_7357.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_9047.1 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_4828.1 3 Reactome: R-HSA-9634638;Reactome: R-HSA-5663220;Reactome: R-HSA-525793 "Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins";"Myogenesis" JAMg_model_3293.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_21027.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" JAMg_model_5317.2 1 Reactome: R-HSA-71384 "Ethanol oxidation" JAMg_model_16086.1 2 Reactome: R-HSA-71240;KEGG: 00380+1.13.11.11 "Tryptophan catabolism";"Tryptophan metabolism" JAMg_model_16807.1 3 Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1 "Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism" JAMg_model_6324.3 10 MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.15;KEGG: 00561+2.3.1.15 "Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Glycerolipid metabolism" JAMg_model_18697.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" JAMg_model_12498.1 3 Reactome: R-HSA-5083627;Reactome: R-HSA-5173105;Reactome: R-HSA-2022854 "Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation";"Keratan sulfate biosynthesis" JAMg_model_5847.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" JAMg_model_6932.2 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" JAMg_model_9009.1 4 MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism" JAMg_model_20979.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_20927.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" JAMg_model_16961.3 3 Reactome: R-HSA-6807505;Reactome: R-HSA-749476;Reactome: R-HSA-76071 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" JAMg_model_2104.3 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_13747.2 29 Reactome: R-HSA-427413;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-73772;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-167200;Reactome: R-HSA-5696395;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-73863;Reactome: R-HSA-76042;Reactome: R-HSA-6781823 "NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of Incision Complex in GG-NER";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of TC-NER Pre-Incision Complex" JAMg_model_13433.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_7069.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" JAMg_model_10771.1 1 Reactome: R-HSA-912446 "Meiotic recombination" JAMg_model_20773.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" JAMg_model_20334.12 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" JAMg_model_11657.3 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" JAMg_model_2904.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294 "SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors" JAMg_model_18860.1 2 Reactome: R-HSA-8854214;Reactome: R-HSA-8873719 "TBC/RABGAPs";"RAB geranylgeranylation" JAMg_model_11805.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" JAMg_model_6815.3 6 Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444 "EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" JAMg_model_16827.1 6 Reactome: R-HSA-6803204;Reactome: R-HSA-6803205;Reactome: R-HSA-6804759;Reactome: R-HSA-6803211;Reactome: R-HSA-139915;Reactome: R-HSA-6803207 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Death Receptors and Ligands";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Caspase Activators and Caspases" JAMg_model_12166.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" JAMg_model_13508.2 3 Reactome: R-HSA-975577;Reactome: R-HSA-2022854;Reactome: R-HSA-913709 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis";"O-linked glycosylation of mucins" JAMg_model_9982.1 19 MetaCyc: PWY-7291;MetaCyc: PWY-735;MetaCyc: PWY-7854;MetaCyc: PWY-7288;MetaCyc: PWY-7338;KEGG: 00592+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7337;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-6920;MetaCyc: PWY-7340;MetaCyc: PWY-5136;MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6 "Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism" JAMg_model_8756.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_4623.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" JAMg_model_12325.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" JAMg_model_21281.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis" JAMg_model_9858.2 5 Reactome: R-HSA-9614657;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-381183;Reactome: R-HSA-380994 "FOXO-mediated transcription of cell death genes";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress" JAMg_model_12554.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" JAMg_model_980.2 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" JAMg_model_3950.1 20 MetaCyc: PWY-7007;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7338;MetaCyc: PWY-7291;MetaCyc: PWY-7854;MetaCyc: PWY-735;MetaCyc: PWY-6920;MetaCyc: PWY-7340;MetaCyc: PWY-5136;Reactome: R-HSA-9033241;MetaCyc: PWY-7574;MetaCyc: PWY-7337;MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6 "Methyl ketone biosynthesis (engineered)";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Peroxisomal protein import";"Propanoyl-coa degradation II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism" JAMg_model_6825.1 2 Reactome: R-HSA-5683371;Reactome: R-HSA-1369007 "Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters" JAMg_model_2059.6 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_10024.4 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_19425.2 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" JAMg_model_15672.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_16666.2 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" JAMg_model_7013.2 2 Reactome: R-HSA-5578998;Reactome: R-HSA-174403 "Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling" JAMg_model_6018.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_13504.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_9755.3 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" JAMg_model_14641.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" JAMg_model_21260.4 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" JAMg_model_8637.4 4 Reactome: R-HSA-4720454;KEGG: 00513+2.4.1.261;KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-446193 "Defective ALG9 causes ALG9-CDG (CDG-1l)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" JAMg_model_8288.3 4 Reactome: R-HSA-9020702;Reactome: R-HSA-937039;MetaCyc: PWY-7511;Reactome: R-HSA-975144 "Interleukin-1 signaling";"IRAK1 recruits IKK complex";"Protein ubiquitination";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation" JAMg_model_390.2 3 Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-5250924 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression" JAMg_model_14078.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" JAMg_model_1257.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" JAMg_model_12633.1 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_18090.4 3 MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" JAMg_model_14676.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" JAMg_model_5359.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" JAMg_model_14764.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_13321.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.1 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" JAMg_model_10975.2 2 Reactome: R-HSA-6811436;Reactome: R-HSA-8876198 "COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs" JAMg_model_5197.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" JAMg_model_15796.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" JAMg_model_12523.2 3 Reactome: R-HSA-1237112;MetaCyc: PWY-4361;KEGG: 00270+1.13.11.54 "Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism" JAMg_model_19791.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway" JAMg_model_12111.2 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" JAMg_model_16889.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733 "Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis" JAMg_model_7356.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_18024.2 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" JAMg_model_1117.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_14654.7 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" JAMg_model_16845.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" JAMg_model_6375.4 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_8807.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection" JAMg_model_9948.3 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" JAMg_model_12968.1 4 KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;MetaCyc: PWY-6483;Reactome: R-HSA-1660662 "Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Ceramide degradation (generic)";"Glycosphingolipid metabolism" JAMg_model_2588.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" JAMg_model_6941.2 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" JAMg_model_9194.1 6 KEGG: 00670+2.1.2.3;MetaCyc: PWY-7234;KEGG: 00230+3.5.4.10+2.1.2.3;Reactome: R-HSA-73817;MetaCyc: PWY-6123;MetaCyc: PWY-6124 "One carbon pool by folate";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II" JAMg_model_12727.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" JAMg_model_1687.2 16 Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-179409;Reactome: R-HSA-983168 "Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_4517.1 10 Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-167172 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome" JAMg_model_5776.6 3 Reactome: R-HSA-1614603;Reactome: R-HSA-1614558;Reactome: R-HSA-2408508 "Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" JAMg_model_4565.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_2597.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" JAMg_model_4900.1 24 Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-9609736;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434 "The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Kinesins";"HCMV Early Events";"Mitotic Prometaphase";"Assembly and cell surface presentation of NMDA receptors";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_10920.1 28 Reactome: R-HSA-68962;Reactome: R-HSA-174437;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-5696397;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-6782210;Reactome: R-HSA-69166;Reactome: R-HSA-176187;Reactome: R-HSA-912446;Reactome: R-HSA-3371511;Reactome: R-HSA-5696395;Reactome: R-HSA-5685938;Reactome: R-HSA-3371453;Reactome: R-HSA-110314;Reactome: R-HSA-6804756;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-6783310;Reactome: R-HSA-5655862 "Activation of the pre-replicative complex";"Removal of the Flap Intermediate from the C-strand";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate";"Activation of ATR in response to replication stress";"Meiotic recombination";"HSF1 activation";"Formation of Incision Complex in GG-NER";"HDR through Single Strand Annealing (SSA)";"Regulation of HSF1-mediated heat shock response";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Translesion synthesis by REV1";"Dual incision in TC-NER";"Fanconi Anemia Pathway";"Translesion synthesis by POLK" JAMg_model_7189.1 12 Reactome: R-HSA-418885;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-193648 "DCC mediated attractive signaling";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Rho GTPase cycle";"Human papillomavirus infection";"Relaxin signaling pathway";"G alpha (q) signalling events";"NRAGE signals death through JNK" JAMg_model_7461.3 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_11757.3 6 Reactome: R-HSA-8874211;Reactome: R-HSA-381033;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-1655829;Reactome: R-HSA-8963889 "CREB3 factors activate genes";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Assembly of active LPL and LIPC lipase complexes" JAMg_model_21191.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" JAMg_model_11795.2 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_3952.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-975956 "Peptide chain elongation";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" JAMg_model_12326.1 24 Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-1445148 "Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"HCMV Early Events";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" JAMg_model_8298.7 4 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-1912420 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi" JAMg_model_7624.2 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_8098.2 1 Reactome: R-HSA-163841 "Gamma carboxylation, hypusine formation and arylsulfatase activation" JAMg_model_6375.6 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_15014.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_8375.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" JAMg_model_7052.4 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" JAMg_model_3237.6 13 Reactome: R-HSA-167590;Reactome: R-HSA-2132295;Reactome: R-HSA-416993;Reactome: R-HSA-8866427;Reactome: R-HSA-182218;Reactome: R-HSA-8964038;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-177504;Reactome: R-HSA-5099900;Reactome: R-HSA-437239;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Nef Mediated CD4 Down-regulation";"MHC class II antigen presentation";"Trafficking of GluR2-containing AMPA receptors";"VLDLR internalisation and degradation";"Nef Mediated CD8 Down-regulation";"LDL clearance";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Retrograde neurotrophin signalling";"WNT5A-dependent internalization of FZD4";"Recycling pathway of L1";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" JAMg_model_19167.2 11 MetaCyc: PWY-8051;KEGG: 00565+3.1.3.4;KEGG: 00561+3.1.3.4;Reactome: R-HSA-2029485;KEGG: 00600+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-8052;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-6453 "Anandamide biosynthesis I";"Ether lipid metabolism";"Glycerolipid metabolism";"Role of phospholipids in phagocytosis";"Sphingolipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"2-arachidonoylglycerol biosynthesis";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis" JAMg_model_14335.1 19 MetaCyc: PWY-7726;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7574;MetaCyc: PWY-5136;MetaCyc: PWY-6920;MetaCyc: PWY-7340;MetaCyc: PWY-7854;MetaCyc: PWY-735;MetaCyc: PWY-7291;MetaCyc: PWY-7338;MetaCyc: PWY-7288;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858;KEGG: 00592+1.3.3.6 "(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation II (plant peroxisome)";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II";"alpha-Linolenic acid metabolism" JAMg_model_12018.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" JAMg_model_19244.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" JAMg_model_7425.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" JAMg_model_17851.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_15812.2 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" JAMg_model_7862.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_7222.2 16 Reactome: R-HSA-9010553;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-983168;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-674695;Reactome: R-HSA-8951664 "Regulation of expression of SLITs and ROBOs";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Antigen processing: Ubiquitination & Proteasome degradation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RNA Polymerase II Pre-transcription Events";"Neddylation" JAMg_model_18188.2 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" JAMg_model_7499.1 11 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 05165+2.7.11.1;Reactome: R-HSA-8866654;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693571;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1834949;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"IRF3-mediated induction of type I IFN";"Human papillomavirus infection";"E3 ubiquitin ligases ubiquitinate target proteins";"PI3K-Akt signaling pathway";"Nonhomologous End-Joining (NHEJ)";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Cytosolic sensors of pathogen-associated DNA";"Human cytomegalovirus infection" JAMg_model_1263.1 5 Reactome: R-HSA-918233;Reactome: R-HSA-9013973;Reactome: R-HSA-936964;Reactome: R-HSA-936440;Reactome: R-HSA-933541 "TRAF3-dependent IRF activation pathway";"TICAM1-dependent activation of IRF3/IRF7";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Negative regulators of DDX58/IFIH1 signaling";"TRAF6 mediated IRF7 activation" JAMg_model_16739.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" JAMg_model_5049.1 17 Reactome: R-HSA-5358565;Reactome: R-HSA-5696397;Reactome: R-HSA-174437;Reactome: R-HSA-5358606;Reactome: R-HSA-69183;Reactome: R-HSA-6782210;Reactome: R-HSA-174417;Reactome: R-HSA-69166;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-174414;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-5651801 "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand (Lagging Strand) Synthesis";"Removal of the Flap Intermediate";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Polymerase switching";"Processive synthesis on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair" JAMg_model_957.8 4 Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434 "Kinesins";"RHO GTPases activate KTN1";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_8168.1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" JAMg_model_12301.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" JAMg_model_583.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" JAMg_model_3063.2 1 Reactome: R-HSA-1632852 "Macroautophagy" JAMg_model_18058.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" JAMg_model_15662.1 13 MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2024101 "Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"CS/DS degradation" JAMg_model_6542.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" JAMg_model_16905.2 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" JAMg_model_19962.2 16 Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553 "Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs" JAMg_model_16243.3 1 Reactome: R-HSA-1483148 "Synthesis of PG" JAMg_model_9520.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" JAMg_model_17987.1 10 Reactome: R-HSA-73779;Reactome: R-HSA-3214847;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HATs acetylate histones";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events" JAMg_model_20213.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_8852.2 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" JAMg_model_6178.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" JAMg_model_3952.2 16 Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695 "Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex" JAMg_model_17739.2 13 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-6791226 "Peptide chain elongation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_9781.2 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_6589.2 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" JAMg_model_13194.2 4 Reactome: R-HSA-70895;MetaCyc: PWY-5642;KEGG: 00640+1.2.1.27;KEGG: 00280+1.2.1.27 "Branched-chain amino acid catabolism";"2,4-dinitrotoluene degradation";"Propanoate metabolism";"Valine, leucine and isoleucine degradation" JAMg_model_2672.1 5 Reactome: R-HSA-1834941;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-3249367;Reactome: R-HSA-3134975 "STING mediated induction of host immune responses";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"STAT6-mediated induction of chemokines";"Regulation of innate immune responses to cytosolic DNA" JAMg_model_13056.4 13 Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72764 "L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination" JAMg_model_1575.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" JAMg_model_3662.2 16 Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72689 "Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits" JAMg_model_13391.1 13 Reactome: R-HSA-983695;Reactome: R-HSA-139853;Reactome: R-HSA-114508;Reactome: R-HSA-112043;Reactome: R-HSA-5607763;Reactome: R-HSA-4086398;Reactome: R-HSA-2029485;Reactome: R-HSA-5578775;Reactome: R-HSA-2871809;Reactome: R-HSA-381676;Reactome: R-HSA-422356;Reactome: R-HSA-5218921;Reactome: R-HSA-1489509 "Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Elevation of cytosolic Ca2+ levels";"Effects of PIP2 hydrolysis";"PLC beta mediated events";"CLEC7A (Dectin-1) induces NFAT activation";"Ca2+ pathway";"Role of phospholipids in phagocytosis";"Ion homeostasis";"FCERI mediated Ca+2 mobilization";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Regulation of insulin secretion";"VEGFR2 mediated cell proliferation";"DAG and IP3 signaling" JAMg_model_20907.1 9 Reactome: R-HSA-2022928;Reactome: R-HSA-2024096;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-975634;Reactome: R-HSA-3656237;Reactome: R-HSA-4420332;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801 "HS-GAG biosynthesis";"HS-GAG degradation";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"Retinoid metabolism and transport";"Defective EXT2 causes exostoses 2";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD" JAMg_model_14769.2 2 Reactome: R-HSA-212676;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" JAMg_model_7883.1 1 Reactome: R-HSA-2565942 "Regulation of PLK1 Activity at G2/M Transition" JAMg_model_7193.2 4 Reactome: R-HSA-5688399;Reactome: R-HSA-5683826;Reactome: R-HSA-1369062;Reactome: R-HSA-5683678 "Defective ABCA3 causes pulmonary surfactant metabolism dysfunction 3 (SMDP3)";"Surfactant metabolism";"ABC transporters in lipid homeostasis";"Defective ABCA3 causes pulmonary surfactant metabolism dysfunction type 3 (SMDP3)" JAMg_model_5764.3 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" JAMg_model_10656.1 3 Reactome: R-HSA-9645722;Reactome: R-HSA-111471;Reactome: R-HSA-140837 "Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Apoptotic factor-mediated response";"Intrinsic Pathway of Fibrin Clot Formation" JAMg_model_21255.1 25 Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-380270;Reactome: R-HSA-8955332;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497 "Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"Mitotic Prometaphase";"HCMV Early Events";"Kinesins";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"Carboxyterminal post-translational modifications of tubulin";"Aggrephagy";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" JAMg_model_11252.1 9 KEGG: 00564+1.1.1.94;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7385;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-7902;MetaCyc: PWY-5667;MetaCyc: PWY-6118;MetaCyc: PWY-5981 "Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis III" JAMg_model_21285.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" JAMg_model_10868.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_9533.1 8 MetaCyc: PWY-6372;MetaCyc: PWY-6664;KEGG: 00562+5.5.1.4;KEGG: 00521+5.5.1.4;Reactome: R-HSA-1855183;MetaCyc: PWY-4661;MetaCyc: PWY-6580;MetaCyc: PWY-2301 "1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Di-myo-inositol phosphate biosynthesis";"Inositol phosphate metabolism";"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol biosynthesis I (bacteria)";"Myo-inositol biosynthesis" JAMg_model_19003.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_2802.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" JAMg_model_3407.1 6 Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-5685938 "Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)" JAMg_model_5369.1 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" JAMg_model_10724.1 1 Reactome: R-HSA-70921 "Histidine catabolism" JAMg_model_19743.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" JAMg_model_18933.1 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_12573.6 18 KEGG: 00630+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-5392;MetaCyc: PWY-7115;KEGG: 00680+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-5913;MetaCyc: PWY-6969;KEGG: 00270+1.1.1.37;KEGG: 00720+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-5690;KEGG: 00710+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00020+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-7383 "Glyoxylate and dicarboxylate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Reductive TCA cycle II";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Methane metabolism";"Pyruvate metabolism";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Cysteine and methionine metabolism";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis";"TCA cycle II (plants and fungi)";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation I (serine pathway)";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Anaerobic energy metabolism (invertebrates, cytosol)" JAMg_model_11794.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" JAMg_model_17015.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" JAMg_model_8709.2 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" JAMg_model_1642.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" JAMg_model_13545.5 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" JAMg_model_7836.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_14430.1 5 KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-6855 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)" JAMg_model_12909.2 6 MetaCyc: PWY-5530;KEGG: 00053+3.1.1.17;KEGG: 00930+3.1.1.17;KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-2221 "Sorbitol biosynthesis II";"Ascorbate and aldarate metabolism";"Caprolactam degradation";"Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)" JAMg_model_8940.3 5 Reactome: R-HSA-9633012;Reactome: R-HSA-9648895;KEGG: 00250+6.3.5.4;Reactome: R-HSA-380994;Reactome: R-HSA-8963693 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Response of EIF2AK1 (HRI) to heme deficiency";"Alanine, aspartate and glutamate metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Aspartate and asparagine metabolism" JAMg_model_11256.1 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" JAMg_model_2162.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_3981.3 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" JAMg_model_9797.8 1 Reactome: R-HSA-191273 "Cholesterol biosynthesis" JAMg_model_8132.1 6 MetaCyc: PWY-6906;MetaCyc: PWY-5514;KEGG: 00520+5.4.2.3;KEGG: 00520+5.4.2.10;Reactome: R-HSA-446210;MetaCyc: PWY-6749 "Chitin derivatives degradation";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I" JAMg_model_3210.2 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" JAMg_model_16126.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" JAMg_model_19491.7 4 Reactome: R-HSA-1362409;Reactome: R-HSA-947581;MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7 "Mitochondrial iron-sulfur cluster biogenesis";"Molybdenum cofactor biosynthesis";"[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism" JAMg_model_10021.6 4 Reactome: R-HSA-1855183;KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841;KEGG: 00053+1.13.99.1 "Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Ascorbate and aldarate metabolism" JAMg_model_6941.4 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" JAMg_model_12861.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" JAMg_model_7514.1 4 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-8866654 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins" JAMg_model_1151.1 1 Reactome: R-HSA-8950505 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" JAMg_model_17694.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_5267.1 4 KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219 "Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis" JAMg_model_18122.1 7 KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6351;MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11 "Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism" JAMg_model_17468.1 1 Reactome: R-HSA-6785631 "ERBB2 Regulates Cell Motility" JAMg_model_8693.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" JAMg_model_14158.3 6 Reactome: R-HSA-975634;Reactome: R-HSA-6798695;Reactome: R-HSA-3000171;Reactome: R-HSA-2453864;Reactome: R-HSA-2453902;Reactome: R-HSA-977225 "Retinoid metabolism and transport";"Neutrophil degranulation";"Non-integrin membrane-ECM interactions";"Retinoid cycle disease events";"The canonical retinoid cycle in rods (twilight vision)";"Amyloid fiber formation" JAMg_model_10817.5 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_4961.4 5 Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-182971 "Negative regulation of MET activity";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation" JAMg_model_15016.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" JAMg_model_10409.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-8876198;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic" JAMg_model_7182.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" JAMg_model_17337.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" JAMg_model_2063.1 30 Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-6796648;Reactome: R-HSA-5696395;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-427413;Reactome: R-HSA-6782135;Reactome: R-HSA-2564830;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-5696400;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-73863;Reactome: R-HSA-76042;Reactome: R-HSA-6781823;Reactome: R-HSA-167162;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-6782210 "RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of Incision Complex in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"NoRC negatively regulates rRNA expression";"Dual incision in TC-NER";"Cytosolic iron-sulfur cluster assembly";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Dual Incision in GG-NER";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II HIV Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Gap-filling DNA repair synthesis and ligation in TC-NER" JAMg_model_18526.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" JAMg_model_14123.1 6 Reactome: R-HSA-5609978;MetaCyc: PWY-6527;KEGG: 00520+2.7.7.12;KEGG: 00052+2.7.7.12;MetaCyc: PWY-6317;Reactome: R-HSA-70370 "Defective GALT can cause Galactosemia";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Galactose catabolism" JAMg_model_4350.2 1 Reactome: R-HSA-8949664 "Processing of SMDT1" JAMg_model_9015.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012 "L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Viral mRNA Translation";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency" JAMg_model_3471.1 3 MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181 "Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism" JAMg_model_16125.2 3 Reactome: R-HSA-6784531;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470 "tRNA processing in the nucleus";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion" JAMg_model_8098.4 1 Reactome: R-HSA-163841 "Gamma carboxylation, hypusine formation and arylsulfatase activation" JAMg_model_3665.1 7 KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" JAMg_model_20393.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2" JAMg_model_6806.1 1 Reactome: R-HSA-5635838 "Activation of SMO" JAMg_model_9236.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" JAMg_model_8834.1 10 MetaCyc: PWY-7511;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6804756 "Protein ubiquitination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation" JAMg_model_20695.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" JAMg_model_16208.2 5 Reactome: R-HSA-199220;Reactome: R-HSA-163765;Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558 "Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis" JAMg_model_2273.5 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" JAMg_model_11335.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" JAMg_model_3430.1 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" JAMg_model_2846.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" JAMg_model_18048.4 5 Reactome: R-HSA-70171;MetaCyc: PWY-6906;MetaCyc: PWY-5514;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6 "Glycolysis";"Chitin derivatives degradation";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism" JAMg_model_16516.1 10 MetaCyc: PWY-6807;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;Reactome: R-HSA-2024096;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23 "Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"HS-GAG degradation";"Other glycan degradation";"Galactose metabolism";"Neutrophil degranulation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Glycosaminoglycan degradation" JAMg_model_16624.2 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" JAMg_model_4554.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" JAMg_model_7757.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" JAMg_model_14715.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" JAMg_model_17786.1 2 Reactome: R-HSA-389661;KEGG: 00785+6.3.1.20 "Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism" JAMg_model_12587.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_14896.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_7638.2 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_3815.1 1 Reactome: R-HSA-1632852 "Macroautophagy" JAMg_model_6484.3 10 Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-3108214;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942 "HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"SUMOylation of DNA damage response and repair proteins";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)" JAMg_model_872.1 4 MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1;Reactome: R-HSA-71737;MetaCyc: PWY-7807 "(aminomethyl)phosphonate degradation";"Oxidative phosphorylation";"Pyrophosphate hydrolysis";"Glyphosate degradation III" JAMg_model_13215.1 32 Reactome: R-HSA-174437;Reactome: R-HSA-68962;Reactome: R-HSA-5693616;Reactome: R-HSA-5358565;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-69166;Reactome: R-HSA-912446;Reactome: R-HSA-3108214;Reactome: R-HSA-5685938;Reactome: R-HSA-3371453;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-69473;Reactome: R-HSA-5358606;Reactome: R-HSA-201722;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-5693607;Reactome: R-HSA-5689880;Reactome: R-HSA-6782210;Reactome: R-HSA-176187;Reactome: R-HSA-3214847;Reactome: R-HSA-3371511;Reactome: R-HSA-5696395;Reactome: R-HSA-6804756;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135;Reactome: R-HSA-6783310 "Removal of the Flap Intermediate from the C-strand";"Activation of the pre-replicative complex";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate";"Meiotic recombination";"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)";"Regulation of HSF1-mediated heat shock response";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"G2/M DNA damage checkpoint";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Formation of the beta-catenin:TCF transactivating complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Processing of DNA double-strand break ends";"Ub-specific processing proteases";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of ATR in response to replication stress";"HATs acetylate histones";"HSF1 activation";"Formation of Incision Complex in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI";"Dual incision in TC-NER";"Fanconi Anemia Pathway" JAMg_model_19224.2 1 Reactome: R-HSA-5676934 "Protein repair" JAMg_model_3197.2 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" JAMg_model_11151.1 13 Reactome: R-HSA-9649948;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674135;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6802948;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6802955 "Signaling downstream of RAS mutants";"Human cytomegalovirus infection";"MAP2K and MAPK activation";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Signaling by high-kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF" JAMg_model_15093.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_8515.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" JAMg_model_21355.3 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" JAMg_model_4734.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" JAMg_model_1096.4 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" JAMg_model_3438.2 3 Reactome: R-HSA-2129379;Reactome: R-HSA-1566948;Reactome: R-HSA-1474228 "Molecules associated with elastic fibres";"Elastic fibre formation";"Degradation of the extracellular matrix" JAMg_model_21179.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_14961.6 4 Reactome: R-HSA-389661;KEGG: 00785+2.8.1.8;MetaCyc: PWY-6987;MetaCyc: PWY-7382 "Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)" JAMg_model_1646.1 6 MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23 "Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Other glycan degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism" JAMg_model_1150.1 5 Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084 "Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA" JAMg_model_13393.2 13 Reactome: R-HSA-381676;Reactome: R-HSA-422356;Reactome: R-HSA-5218921;Reactome: R-HSA-1489509;Reactome: R-HSA-983695;Reactome: R-HSA-139853;Reactome: R-HSA-114508;Reactome: R-HSA-112043;Reactome: R-HSA-5607763;Reactome: R-HSA-4086398;Reactome: R-HSA-2029485;Reactome: R-HSA-5578775;Reactome: R-HSA-2871809 "Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Regulation of insulin secretion";"VEGFR2 mediated cell proliferation";"DAG and IP3 signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Elevation of cytosolic Ca2+ levels";"Effects of PIP2 hydrolysis";"PLC beta mediated events";"CLEC7A (Dectin-1) induces NFAT activation";"Ca2+ pathway";"Role of phospholipids in phagocytosis";"Ion homeostasis";"FCERI mediated Ca+2 mobilization" JAMg_model_13503.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" JAMg_model_7371.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" JAMg_model_2708.1 1 Reactome: R-HSA-2995383 "Initiation of Nuclear Envelope Reformation" JAMg_model_8550.3 14 MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-5972;Reactome: R-HSA-75876 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs" JAMg_model_15441.8 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" JAMg_model_16767.1 2 KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336 "Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway" JAMg_model_17246.1 4 Reactome: R-HSA-70263;KEGG: 00010+3.1.3.9;KEGG: 00500+3.1.3.9;KEGG: 00052+3.1.3.9 "Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Galactose metabolism" JAMg_model_18299.3 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" JAMg_model_12370.1 6 MetaCyc: PWY-5743;MetaCyc: PWY-6722;Reactome: R-HSA-196780;MetaCyc: PWY-4381;MetaCyc: PWY-5744;MetaCyc: PWY-5789 "3-hydroxypropanoate cycle";"Candicidin biosynthesis";"Biotin transport and metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle" JAMg_model_20442.1 4 Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257 "Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion" JAMg_model_12391.5 7 KEGG: 00562+2.7.8.11;KEGG: 04070+2.7.8.11;MetaCyc: PWY-6352;Reactome: R-HSA-1483226;KEGG: 00564+2.7.8.11;MetaCyc: PWY-7625;MetaCyc: PWY-6351 "Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"3-phosphoinositide biosynthesis";"Synthesis of PI";"Glycerophospholipid metabolism";"Phosphatidylinositol biosynthesis II (eukaryotes)";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis" JAMg_model_9141.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" JAMg_model_897.1 3 Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification" JAMg_model_17450.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" JAMg_model_8092.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" JAMg_model_14518.4 1 Reactome: R-HSA-5620924 "Intraflagellar transport" JAMg_model_293.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" JAMg_model_10609.1 5 KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III" JAMg_model_1329.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" JAMg_model_17299.1 11 MetaCyc: PWY-6992;MetaCyc: PWY-7586;Reactome: R-HSA-4043916;KEGG: 00051+5.3.1.8;KEGG: 00520+5.3.1.8;Reactome: R-HSA-446205;MetaCyc: PWY-3881;MetaCyc: PWY-7456;MetaCyc: PWY-5659;MetaCyc: PWY-3861;MetaCyc: PWY-882 "1,5-anhydrofructose degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Defective MPI causes MPI-CDG (CDG-1b)";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"Mannitol biosynthesis";"Beta-(1,4)-mannan degradation";"GDP-mannose biosynthesis";"Mannitol degradation II";"L-ascorbate biosynthesis I (L-galactose pathway)" JAMg_model_480.2 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" JAMg_model_5030.3 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" JAMg_model_1733.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" JAMg_model_18904.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_21214.1 40 MetaCyc: PWY-6946;MetaCyc: PWY-7094;MetaCyc: PWY-6863;MetaCyc: PWY-7654;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;MetaCyc: PWY-6435;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;MetaCyc: PWY-7778;MetaCyc: PWY-1361;KEGG: 00623+1.1.1.35;KEGG: 00640+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;MetaCyc: PWY-7779;MetaCyc: PWY-7216;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;MetaCyc: PWY-6883;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;KEGG: 00627+4.2.1.17;KEGG: 00410+4.2.1.17;MetaCyc: PWY-5177;MetaCyc: PWY-6583;MetaCyc: PWY-5138;MetaCyc: PWY-6944;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7007;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;MetaCyc: PWY-7726;MetaCyc: PWY-7401;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17 "Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Fatty acid salvage";"Pyruvate fermentation to hexanol (engineered)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fatty acid elongation";"Fatty acid beta-oxidation II (plant peroxisome)";"4-hydroxybenzoate biosynthesis III (plants)";"Butanoate metabolism";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"2-methylpropene degradation";"Benzoyl-coa degradation I (aerobic)";"Toluene degradation";"Propanoate metabolism";"Geraniol degradation";"Caprolactam degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl tert-butyl ether degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Carbon fixation pathways in prokaryotes";"Spodoptera littoralis pheromone biosynthesis";"Pyruvate fermentation to butanol II (engineered)";"Valine, leucine and isoleucine degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Lysine degradation";"Phenylalanine metabolism";"Aminobenzoate degradation";"beta-Alanine metabolism";"Glutaryl-coa degradation";"Pyruvate fermentation to butanol I";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Androstenedione degradation";"Limonene and pinene degradation";"Methyl ketone biosynthesis (engineered)";"Benzoate degradation";"Tryptophan metabolism";"Fermentation to 2-methylbutanoate";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Fatty acid degradation";"alpha-Linolenic acid metabolism" JAMg_model_3397.1 11 Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-400253;Reactome: R-HSA-383280;Reactome: R-HSA-1368082;Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108 "Estrogen-dependent gene expression";"PPARA activates gene expression";"Generic Transcription Pathway";"Circadian Clock";"Nuclear Receptor transcription pathway";"RORA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" JAMg_model_19237.1 1 Reactome: R-HSA-1632852 "Macroautophagy" JAMg_model_12827.2 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" JAMg_model_11835.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" JAMg_model_20334.2 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" JAMg_model_14802.2 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" JAMg_model_12677.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" JAMg_model_5587.3 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" JAMg_model_16474.5 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" JAMg_model_6052.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" JAMg_model_10684.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" JAMg_model_9299.1 1 Reactome: R-HSA-5689603 "UCH proteinases" JAMg_model_11352.3 2 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine, serine and threonine metabolism" JAMg_model_9900.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" JAMg_model_20006.2 5 Reactome: R-HSA-6811434;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-204005 "COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport" JAMg_model_6941.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" JAMg_model_15526.2 7 KEGG: 00230+3.6.1.15;MetaCyc: PWY-7198;MetaCyc: PWY-7184;KEGG: 00730+3.6.1.15;MetaCyc: PWY-7185;MetaCyc: PWY-6545;MetaCyc: PWY-7210 "Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Thiamine metabolism";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" JAMg_model_14998.1 3 KEGG: 00230+3.6.1.17;KEGG: 00240+3.6.1.17;Reactome: R-HSA-3299685 "Purine metabolism";"Pyrimidine metabolism";"Detoxification of Reactive Oxygen Species" JAMg_model_2105.1 1 Reactome: R-HSA-419771 "Opsins" JAMg_model_4998.3 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" JAMg_model_20961.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" JAMg_model_1674.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" JAMg_model_13671.2 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" JAMg_model_10817.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_18119.1 7 MetaCyc: PWY-7221;MetaCyc: PWY-5695;KEGG: 00230+1.1.1.205;Reactome: R-HSA-73817;Reactome: R-HSA-6798695;MetaCyc: PWY-6596;KEGG: 00983+1.1.1.205 "Guanosine ribonucleotides de novo biosynthesis";"Inosine 5'-phosphate degradation";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Neutrophil degranulation";"Adenosine nucleotides degradation I";"Drug metabolism - other enzymes" JAMg_model_2182.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" JAMg_model_16589.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" JAMg_model_2602.2 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" JAMg_model_19272.5 2 Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22 "Histidine catabolism";"Histidine metabolism" JAMg_model_5689.5 2 Reactome: R-HSA-191859;Reactome: R-HSA-6807505 "snRNP Assembly";"RNA polymerase II transcribes snRNA genes" JAMg_model_14338.5 5 Reactome: R-HSA-2022857;Reactome: R-HSA-2206305;Reactome: R-HSA-432720;KEGG: 00531+3.1.6.14;Reactome: R-HSA-6798695 "Keratan sulfate degradation";"MPS IIID - Sanfilippo syndrome D";"Lysosome Vesicle Biogenesis";"Glycosaminoglycan degradation";"Neutrophil degranulation" JAMg_model_16329.2 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" JAMg_model_15707.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733 "Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis" JAMg_model_16460.1 2 KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205 "Starch and sucrose metabolism";"Synthesis of GDP-mannose" JAMg_model_7190.4 12 Reactome: R-HSA-416482;KEGG: 05170+2.7.11.1;Reactome: R-HSA-418885;KEGG: 05163+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-193648;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1 "G alpha (12/13) signalling events";"Human immunodeficiency virus 1 infection";"DCC mediated attractive signaling";"Human cytomegalovirus infection";"Rho GTPase cycle";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"G alpha (q) signalling events";"NRAGE signals death through JNK";"PI3K-Akt signaling pathway";"mTOR signaling pathway" JAMg_model_1025.1 5 KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661 "Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation" JAMg_model_15869.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" JAMg_model_6484.1 10 Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-3108214;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938 "HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"SUMOylation of DNA damage response and repair proteins";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)" JAMg_model_4116.9 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" JAMg_model_1216.4 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_16533.1 2 Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Cargo concentration in the ER";"COPII-mediated vesicle transport" JAMg_model_4151.1 2 Reactome: R-HSA-499943;KEGG: 00450+1.8.1.9 "Interconversion of nucleotide di- and triphosphates";"Selenocompound metabolism" JAMg_model_8803.3 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" JAMg_model_1335.2 7 MetaCyc: PWY-7511;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606 "Protein ubiquitination";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" JAMg_model_4004.1 17 MetaCyc: PWY-7224;MetaCyc: PWY-7222;MetaCyc: PWY-7176;MetaCyc: PWY-7227;MetaCyc: PWY-7187;MetaCyc: PWY-7221;MetaCyc: PWY-6545;MetaCyc: PWY-7205;MetaCyc: PWY-7184;MetaCyc: PWY-7197;KEGG: 00983+2.7.4.6;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7220;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7210 "Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Drug metabolism - other enzymes";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" JAMg_model_2741.1 24 Reactome: R-HSA-114604;Reactome: R-HSA-5607764;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5625740;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-1257604;Reactome: R-HSA-9634635;Reactome: R-HSA-165158;Reactome: R-HSA-2730905;Reactome: R-HSA-392451;Reactome: R-HSA-2871837;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804757;KEGG: 05163+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-202424;KEGG: 05170+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-354192 "GPVI-mediated activation cascade";"CLEC7A (Dectin-1) signaling";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"RHO GTPases activate PKNs";"Relaxin signaling pathway";"Human papillomavirus infection";"VEGFR2 mediated cell proliferation";"PIP3 activates AKT signaling";"Estrogen-stimulated signaling through PRKCZ";"Activation of AKT2";"Role of LAT2/NTAL/LAB on calcium mobilization";"G beta:gamma signalling through PI3Kgamma";"FCERI mediated NF-kB activation";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Regulation of TP53 Degradation";"Human cytomegalovirus infection";"CD28 dependent PI3K/Akt signaling";"Downstream TCR signaling";"Human immunodeficiency virus 1 infection";"RSK activation";"Integrin signaling" JAMg_model_7952.1 1 Reactome: R-HSA-350562 "Regulation of ornithine decarboxylase (ODC)" JAMg_model_395.2 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" JAMg_model_4185.4 2 Reactome: R-HSA-70350;Reactome: R-HSA-168928 "Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta" JAMg_model_14657.3 4 Reactome: R-HSA-8939211;Reactome: R-HSA-3371497;Reactome: R-HSA-9018519;Reactome: R-HSA-3371568 "ESR-mediated signaling";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Estrogen-dependent gene expression";"Attenuation phase" JAMg_model_21070.1 16 Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-179409;Reactome: R-HSA-983168 "Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_39.1 12 Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-76061;Reactome: R-HSA-5250924;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73762;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-73863 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Transcription Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Termination" JAMg_model_15923.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_18090.2 3 Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" JAMg_model_11644.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-9633012 "Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" JAMg_model_1964.4 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" JAMg_model_10546.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" JAMg_model_11895.2 5 MetaCyc: PWY-7159;MetaCyc: PWY-5531;KEGG: 00860+4.1.1.37;MetaCyc: PWY-7766;Reactome: R-HSA-189451 "3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Porphyrin and chlorophyll metabolism";"Heme b biosynthesis IV (Gram-positive bacteria)";"Heme biosynthesis" JAMg_model_21315.5 15 KEGG: 00620+2.7.1.40;MetaCyc: PWY-6142;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-2221;MetaCyc: PWY-8004;MetaCyc: PWY-6886;MetaCyc: PWY-5723;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-7383;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7218 "Pyruvate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Glycerol degradation to butanol";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Rubisco shunt";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Purine metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)" JAMg_model_8494.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" JAMg_model_1364.1 1 Reactome: R-HSA-1483101 "Synthesis of PS" JAMg_model_9277.4 3 Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" JAMg_model_10767.3 13 Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Viral mRNA Translation";"Peptide chain elongation" JAMg_model_4682.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" JAMg_model_14837.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_12468.3 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" JAMg_model_19874.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_9288.1 3 Reactome: R-HSA-6794361;Reactome: R-HSA-6798695;Reactome: R-HSA-264870 "Neurexins and neuroligins";"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins" JAMg_model_5495.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" JAMg_model_20524.3 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" JAMg_model_16232.3 4 KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;MetaCyc: PWY-5912;Reactome: R-HSA-156581 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation" JAMg_model_19081.5 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" JAMg_model_21022.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706 "Viral mRNA Translation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit" JAMg_model_17561.2 6 Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257 "Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion" JAMg_model_14336.1 3 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394;Reactome: R-HSA-3214847 "UCH proteinases";"DNA Damage Recognition in GG-NER";"HATs acetylate histones" JAMg_model_20787.1 32 Reactome: R-HSA-73776;Reactome: R-HSA-167242;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-167162;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-72203;Reactome: R-HSA-76042;Reactome: R-HSA-6803529;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-168325;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-167238 "RNA Polymerase II Promoter Escape";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"RNA Polymerase II HIV Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"FGFR2 alternative splicing";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Viral Messenger RNA Synthesis";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation" JAMg_model_12121.4 6 MetaCyc: PWY-6118;Reactome: R-HSA-1483166;MetaCyc: PWY-6952;KEGG: 00564+1.1.5.3;MetaCyc: PWY-4261;Reactome: R-HSA-163560 "Glycerol-3-phosphate shuttle";"Synthesis of PA";"Glycerophosphodiester degradation";"Glycerophospholipid metabolism";"Glycerol degradation I";"Triglyceride catabolism" JAMg_model_16024.2 4 KEGG: 00260+4.2.1.22;MetaCyc: PWY-801;Reactome: R-HSA-1614603;KEGG: 00270+4.2.1.22 "Glycine, serine and threonine metabolism";"Homocysteine and cysteine interconversion";"Cysteine formation from homocysteine";"Cysteine and methionine metabolism" JAMg_model_10403.1 12 Reactome: R-HSA-9013508;Reactome: R-HSA-9013695;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-73762;Reactome: R-HSA-1912408;Reactome: R-HSA-5250924;Reactome: R-HSA-3214847;Reactome: R-HSA-8941856 "NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RNA Polymerase I Transcription Initiation";"Pre-NOTCH Transcription and Translation";"B-WICH complex positively regulates rRNA expression";"HATs acetylate histones";"RUNX3 regulates NOTCH signaling" JAMg_model_7510.1 3 MetaCyc: PWY-7426;Reactome: R-HSA-975574;KEGG: 00510+2.4.1.144 "Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the hybrid N-glycan synthesis pathway";"N-Glycan biosynthesis" JAMg_model_7098.2 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" JAMg_model_15014.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_17939.1 3 Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification" JAMg_model_19228.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" JAMg_model_359.8 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" JAMg_model_3148.1 8 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Signaling by Hippo";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway" JAMg_model_20977.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" JAMg_model_8960.1 1 Reactome: R-HSA-3295583 "TRP channels" JAMg_model_18299.2 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" JAMg_model_6703.1 5 KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.10;KEGG: 00230+2.7.4.3 "Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Purine metabolism" JAMg_model_16063.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" JAMg_model_17598.1 11 Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-3214858;Reactome: R-HSA-1368082;Reactome: R-HSA-6804114;Reactome: R-HSA-400253;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781 "BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"RMTs methylate histone arginines";"RORA activates gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Circadian Clock";"Estrogen-dependent gene expression";"PPARA activates gene expression" JAMg_model_5876.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_186.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Viral mRNA Translation" JAMg_model_2561.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_8725.3 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" JAMg_model_4701.1 4 KEGG: 00860+1.14.14.18;MetaCyc: PWY-5874;Reactome: R-HSA-189483;Reactome: R-HSA-917937 "Porphyrin and chlorophyll metabolism";"Heme degradation I";"Heme degradation";"Iron uptake and transport" JAMg_model_2725.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" JAMg_model_9196.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" JAMg_model_17901.3 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" JAMg_model_10328.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" JAMg_model_21338.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" JAMg_model_20117.2 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" JAMg_model_20341.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6798695 "Protein ubiquitination";"Neutrophil degranulation" JAMg_model_10744.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_3419.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" JAMg_model_13298.1 2 KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019 "Pyrimidine metabolism";"Pseudouridine degradation" JAMg_model_17987.3 10 Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-3214847;Reactome: R-HSA-73779;Reactome: R-HSA-76042 "RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"HATs acetylate histones";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance" JAMg_model_15729.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" JAMg_model_589.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_4016.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_357.2 9 Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-167172 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome" JAMg_model_6525.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" JAMg_model_7796.2 15 Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-8936459;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585 "Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence" JAMg_model_8291.1 33 Reactome: R-HSA-73762;Reactome: R-HSA-5696395;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-75953;Reactome: R-HSA-6782135;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-69656;Reactome: R-HSA-76042;Reactome: R-HSA-69202;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-167162;Reactome: R-HSA-69231;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-6781827;Reactome: R-HSA-69273;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167160;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-8939236;Reactome: R-HSA-167246 "RNA Polymerase I Transcription Initiation";"Formation of Incision Complex in GG-NER";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation";"Dual incision in TC-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Cyclin E associated events during G1/S transition";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II HIV Promoter Escape";"Cyclin D associated events in G1";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Tat-mediated elongation of the HIV-1 transcript" JAMg_model_18440.8 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" JAMg_model_8897.3 3 Reactome: R-HSA-1268020;Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Mitochondrial protein import";"Respiratory electron transport";"Complex I biogenesis" JAMg_model_5876.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_5282.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" JAMg_model_2174.1 1 KEGG: 00565+3.1.1.47 "Ether lipid metabolism" JAMg_model_21343.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" JAMg_model_2351.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" JAMg_model_14402.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_10839.1 11 Reactome: R-HSA-5696397;Reactome: R-HSA-68962;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-68952;Reactome: R-HSA-6782135;Reactome: R-HSA-174430;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801 "Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of the pre-replicative complex";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"DNA replication initiation";"Dual incision in TC-NER";"Telomere C-strand synthesis initiation";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair" JAMg_model_18391.1 5 Reactome: R-HSA-9029558;Reactome: R-HSA-2426168;Reactome: R-HSA-75105;Reactome: R-HSA-199220;Reactome: R-HSA-163765 "NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression" JAMg_model_3475.2 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" JAMg_model_18117.1 12 MetaCyc: PWY-1187;MetaCyc: PWY-6936;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6309;MetaCyc: PWY-601;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6842;MetaCyc: PWY-2821;Reactome: R-HSA-71240;MetaCyc: PWY-7901;MetaCyc: PWY-801;KEGG: 00270+4.4.1.13 "Glucosinolate biosynthesis from homomethionine";"Seleno-amino acid biosynthesis (plants)";"Selenocompound metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from tryptophan";"Tryptophan metabolism";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from phenylalanine";"Tryptophan catabolism";"Glucosinolate biosynthesis from tyrosine";"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism" JAMg_model_21161.7 7 Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284 "Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome" JAMg_model_3093.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68867 "Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex" JAMg_model_8948.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" JAMg_model_21066.3 15 Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-176034;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-2173796;Reactome: R-HSA-9018519;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Interactions of Tat with host cellular proteins";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Estrogen-dependent gene expression";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" JAMg_model_13410.2 4 MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Entner-Doudoroff pathway I";"Pentose phosphate pathway" JAMg_model_5030.5 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" JAMg_model_6318.3 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" JAMg_model_419.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" JAMg_model_18117.2 12 KEGG: 00380+2.6.1.7;MetaCyc: PWY-601;MetaCyc: PWY-6309;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6936;MetaCyc: PWY-1187;KEGG: 00270+4.4.1.13;MetaCyc: PWY-801;MetaCyc: PWY-7901;Reactome: R-HSA-71240;MetaCyc: PWY-2821;MetaCyc: PWY-6842 "Tryptophan metabolism";"Glucosinolate biosynthesis from tryptophan";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Selenocompound metabolism";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from homomethionine";"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from tyrosine";"Tryptophan catabolism";"Glucosinolate biosynthesis from phenylalanine";"Glutathione-mediated detoxification II" JAMg_model_14563.3 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" JAMg_model_13685.1 11 MetaCyc: PWY-6608;MetaCyc: PWY-5695;KEGG: 00983+1.17.3.2;MetaCyc: PWY-6606;MetaCyc: PWY-6596;MetaCyc: PWY-5497;KEGG: 00230+1.17.1.4+1.17.3.2;MetaCyc: PWY-6999;MetaCyc: PWY-6607;KEGG: 00232+1.17.3.2;MetaCyc: PWY-6538 "Guanosine nucleotides degradation III";"Inosine 5'-phosphate degradation";"Drug metabolism - other enzymes";"Guanosine nucleotides degradation II";"Adenosine nucleotides degradation I";"Purine nucleobases degradation II (anaerobic)";"Purine metabolism";"Theophylline degradation";"Guanosine nucleotides degradation I";"Caffeine metabolism";"Caffeine degradation III (bacteria, via demethylation)" JAMg_model_2662.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" JAMg_model_11244.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" JAMg_model_17785.3 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" JAMg_model_11774.1 2 Reactome: R-HSA-380095;Reactome: R-HSA-416476 "Tachykinin receptors bind tachykinins";"G alpha (q) signalling events" JAMg_model_6339.1 1 Reactome: R-HSA-6804756 "Regulation of TP53 Activity through Phosphorylation" JAMg_model_326.3 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_16808.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" JAMg_model_6705.1 5 Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604 "CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling" JAMg_model_20509.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" JAMg_model_15438.1 17 Reactome: R-HSA-202424;Reactome: R-HSA-9020702;Reactome: R-HSA-5357956;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-9014325;Reactome: R-HSA-450302;Reactome: R-HSA-937042;Reactome: R-HSA-445989;Reactome: R-HSA-4086398;Reactome: R-HSA-5607764;Reactome: R-HSA-937072;Reactome: R-HSA-168638;Reactome: R-HSA-5689880;Reactome: R-HSA-450321;Reactome: R-HSA-9645460;Reactome: R-HSA-975163 "Downstream TCR signaling";"Interleukin-1 signaling";"TNFR1-induced NFkappaB signaling pathway";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"TICAM1,TRAF6-dependent induction of TAK1 complex";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Ca2+ pathway";"CLEC7A (Dectin-1) signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"NOD1/2 Signaling Pathway";"Ub-specific processing proteases";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Alpha-protein kinase 1 signaling pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation" JAMg_model_3693.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" JAMg_model_19162.7 1 Reactome: R-HSA-163560 "Triglyceride catabolism" JAMg_model_20871.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" JAMg_model_7979.2 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" JAMg_model_18525.1 2 KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" JAMg_model_2979.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" JAMg_model_19141.2 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" JAMg_model_20317.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" JAMg_model_11757.1 6 Reactome: R-HSA-8874211;Reactome: R-HSA-381033;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-8963889;Reactome: R-HSA-1655829 "CREB3 factors activate genes";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Assembly of active LPL and LIPC lipase complexes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" JAMg_model_9168.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_13025.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_7052.2 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" JAMg_model_19028.1 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_4356.3 3 KEGG: 00510+2.4.1.265;Reactome: R-HSA-446193;Reactome: R-HSA-4724325 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)" JAMg_model_17459.4 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" JAMg_model_13913.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" JAMg_model_11429.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" JAMg_model_20787.12 32 Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167162;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-72203;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-6803529;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167242;Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167172;Reactome: R-HSA-8851708;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-167160;Reactome: R-HSA-72163;Reactome: R-HSA-168325;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167243 "Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription of the HIV genome";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Major Pathway";"Viral Messenger RNA Synthesis";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery" JAMg_model_11882.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" JAMg_model_8140.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" JAMg_model_6310.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" JAMg_model_3319.1 22 KEGG: 00400+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6642;Reactome: R-HSA-72163;KEGG: 00350+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-6638;KEGG: 00360+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-7383;Reactome: R-HSA-73856;MetaCyc: PWY-6643;Reactome: R-HSA-72187;KEGG: 00250+2.6.1.1;Reactome: R-HSA-159236;KEGG: 00401+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00270+2.6.1.1 "Phenylalanine, tyrosine and tryptophan biosynthesis";"Carbon fixation in photosynthetic organisms";"Arginine and proline metabolism";"(R)-cysteate degradation";"mRNA Splicing - Major Pathway";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Sulfolactate degradation III";"Phenylalanine metabolism";"Arginine biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Anaerobic energy metabolism (invertebrates, cytosol)";"RNA Polymerase II Transcription Termination";"Coenzyme M biosynthesis II";"mRNA 3'-end processing";"Alanine, aspartate and glutamate metabolism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Novobiocin biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Cysteine and methionine metabolism" JAMg_model_10932.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_5018.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733 "Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis" JAMg_model_14613.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" JAMg_model_5107.2 6 Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444 "Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" JAMg_model_11411.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" JAMg_model_13705.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" JAMg_model_9186.1 6 MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis" JAMg_model_19084.3 5 Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway" JAMg_model_5103.1 6 MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism" JAMg_model_9279.1 10 Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-382556;Reactome: R-HSA-72702;Reactome: R-HSA-9648895;Reactome: R-HSA-72649;Reactome: R-HSA-381042;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72731 "Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ABC-family proteins mediated transport";"Ribosomal scanning and start codon recognition";"Response of EIF2AK1 (HRI) to heme deficiency";"Translation initiation complex formation";"PERK regulates gene expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Recycling of eIF2:GDP" JAMg_model_1237.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" JAMg_model_4772.2 2 Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" JAMg_model_5272.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" JAMg_model_1382.1 57 Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-4641257 "Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN" JAMg_model_13620.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-8849473 "Major pathway of rRNA processing in the nucleolus and cytosol";"PTK6 Expression" JAMg_model_5978.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" JAMg_model_9895.1 10 MetaCyc: PWY-6317;MetaCyc: PWY-7344;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-3821;MetaCyc: PWY-6397;Reactome: R-HSA-70370;MetaCyc: PWY-7328;KEGG: 00520+5.1.3.2;Reactome: R-HSA-5609977 "D-galactose degradation I (Leloir pathway)";"UDP-alpha-D-galactose biosynthesis";"Galactose metabolism";"Stachyose degradation";"D-galactose detoxification";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose catabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)" JAMg_model_3026.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" JAMg_model_583.4 1 Reactome: R-HSA-71384 "Ethanol oxidation" JAMg_model_19542.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" JAMg_model_13323.1 3 Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-110357 "Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1" JAMg_model_8265.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_20586.3 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" JAMg_model_3753.1 16 Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-174184;Reactome: R-HSA-176409;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-174084 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C" JAMg_model_17980.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" JAMg_model_13044.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_16432.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" JAMg_model_20399.2 8 Reactome: R-HSA-6791226;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "Major pathway of rRNA processing in the nucleolus and cytosol";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" JAMg_model_2620.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_361.4 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" JAMg_model_14757.2 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" JAMg_model_6045.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" JAMg_model_16110.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-5678771;Reactome: R-HSA-382556 "PPARA activates gene expression";"Defective ABCB4 causes progressive familial intrahepatic cholestasis 3, intrahepatic cholestasis of pregnancy 3 and gallbladder disease 1";"ABC-family proteins mediated transport" JAMg_model_9134.1 2 Reactome: R-HSA-446203;Reactome: R-HSA-1799339 "Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane" JAMg_model_5830.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" JAMg_model_907.11 8 Reactome: R-HSA-190873;Reactome: R-HSA-432720;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-8856828 "Gap junction degradation";"Lysosome Vesicle Biogenesis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"Clathrin-mediated endocytosis" JAMg_model_2280.5 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" JAMg_model_17245.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" JAMg_model_15170.1 7 Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232 "Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants" JAMg_model_17797.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72649 "Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Translation initiation complex formation" JAMg_model_15420.2 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" JAMg_model_5690.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-606279 "Fanconi Anemia Pathway";"Deposition of new CENPA-containing nucleosomes at the centromere" JAMg_model_11867.2 5 Reactome: R-HSA-69473;Reactome: R-HSA-3232118;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571 "G2/M DNA damage checkpoint";"SUMOylation of transcription factors";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)" JAMg_model_20043.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" JAMg_model_13456.2 2 Reactome: R-HSA-442982;Reactome: R-HSA-5673001 "Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade" JAMg_model_12710.2 6 MetaCyc: PWY-6908;KEGG: 00730+2.7.6.2;MetaCyc: PWY-7356;MetaCyc: PWY-6907;MetaCyc: PWY-6898;Reactome: R-HSA-196819 "Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine metabolism";"Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage III";"Vitamin B1 (thiamin) metabolism" JAMg_model_10005.1 4 KEGG: 00473+5.1.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-8072;MetaCyc: PWY-8040 "D-Alanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine racemization";"Ansatrienin biosynthesis" JAMg_model_399.1 4 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-430039;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"mRNA decay by 5' to 3' exoribonuclease";"Mitochondrial translation initiation" JAMg_model_7791.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" JAMg_model_11258.1 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" JAMg_model_20929.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444 "EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" JAMg_model_68.1 3 Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23 "Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism" JAMg_model_443.1 1 Reactome: R-HSA-400253 "Circadian Clock" JAMg_model_11842.3 17 Reactome: R-HSA-9633012;Reactome: R-HSA-6790901;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Peptide chain elongation" JAMg_model_14810.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_2146.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" JAMg_model_2777.5 14 Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723 "Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation" JAMg_model_4467.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" JAMg_model_13539.2 7 Reactome: R-HSA-3214815;Reactome: R-HSA-5625886;Reactome: R-HSA-983231;Reactome: R-HSA-8943724;Reactome: R-HSA-9018519;Reactome: R-HSA-3214842;Reactome: R-HSA-9029569 "HDACs deacetylate histones";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Factors involved in megakaryocyte development and platelet production";"Regulation of PTEN gene transcription";"Estrogen-dependent gene expression";"HDMs demethylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" JAMg_model_3554.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" JAMg_model_5266.3 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_12385.2 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" JAMg_model_2059.4 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" JAMg_model_589.2 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" JAMg_model_21104.2 57 Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-6798695;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895 "Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"UCH proteinases";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neutrophil degranulation";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis" JAMg_model_242.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" JAMg_model_9054.2 3 MetaCyc: PWY-0;KEGG: 00330+2.3.1.57;MetaCyc: PWY-6117 "Putrescine degradation III";"Arginine and proline metabolism";"Spermine and spermidine degradation I" JAMg_model_2053.5 1 Reactome: R-HSA-71384 "Ethanol oxidation" JAMg_model_21066.1 15 Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-176034;Reactome: R-HSA-167246;Reactome: R-HSA-9018519;Reactome: R-HSA-2173796;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Interactions of Tat with host cellular proteins";"Tat-mediated elongation of the HIV-1 transcript";"Estrogen-dependent gene expression";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Elongation" JAMg_model_4236.1 1 Reactome: R-HSA-6804754 "Regulation of TP53 Expression" JAMg_model_10547.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase" JAMg_model_8709.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" JAMg_model_3495.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" JAMg_model_5289.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" JAMg_model_6819.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_20244.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" JAMg_model_2840.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_1091.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_3376.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_3822.2 4 Reactome: R-HSA-5693607;Reactome: R-HSA-111465;Reactome: R-HSA-5689880;Reactome: R-HSA-176187 "Processing of DNA double-strand break ends";"Apoptotic cleavage of cellular proteins";"Ub-specific processing proteases";"Activation of ATR in response to replication stress" JAMg_model_859.4 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" JAMg_model_470.1 5 MetaCyc: PWY-5497;KEGG: 00670+4.3.1.4+2.1.2.5;MetaCyc: PWY-5030;KEGG: 00340+2.1.2.5;Reactome: R-HSA-70921 "Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"L-histidine degradation III";"Histidine metabolism";"Histidine catabolism" JAMg_model_15322.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-6784531;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"tRNA processing in the nucleus";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" JAMg_model_12876.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" JAMg_model_15441.5 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" JAMg_model_5673.1 2 Reactome: R-HSA-430039;MetaCyc: PWY-6938 "mRNA decay by 5' to 3' exoribonuclease";"NADH repair" JAMg_model_19035.1 3 Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II" JAMg_model_19272.8 2 Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22 "Histidine catabolism";"Histidine metabolism" JAMg_model_6728.1 57 Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-174154;Reactome: R-HSA-187577 "Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FCERI mediated NF-kB activation";"UCH proteinases";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Interleukin-1 signaling";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21" JAMg_model_10992.5 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" JAMg_model_1080.1 5 KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661 "Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation" JAMg_model_3326.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_20479.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" JAMg_model_6456.1 22 Reactome: R-HSA-70263;MetaCyc: PWY-621;MetaCyc: PWY-7385;MetaCyc: PWY-5659;KEGG: 00030+5.3.1.9;MetaCyc: PWY-3801;MetaCyc: PWY-6992;KEGG: 00500+5.3.1.9;MetaCyc: PWY-5384;MetaCyc: PWY-8013;Reactome: R-HSA-70171;KEGG: 00520+5.3.1.9;MetaCyc: PWY-7238;MetaCyc: PWY-5514;MetaCyc: PWY-6981;MetaCyc: PWY-622;Reactome: R-HSA-6798695;MetaCyc: PWY-7347;Reactome: R-HSA-5628897;MetaCyc: PWY-6142;KEGG: 00010+5.3.1.9;MetaCyc: PWY-5054 "Gluconeogenesis";"Sucrose degradation III (sucrose invertase)";"1,3-propanediol biosynthesis (engineered)";"GDP-mannose biosynthesis";"Pentose phosphate pathway";"Sucrose degradation II (sucrose synthase)";"1,5-anhydrofructose degradation";"Starch and sucrose metabolism";"Sucrose degradation IV (sucrose phosphorylase)";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Sucrose biosynthesis II";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin biosynthesis";"Starch biosynthesis";"Neutrophil degranulation";"Sucrose biosynthesis III";"TP53 Regulates Metabolic Genes";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"D-sorbitol biosynthesis I" JAMg_model_938.2 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" JAMg_model_11741.1 24 Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"Kinesins";"HCMV Early Events";"Mitotic Prometaphase";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion" JAMg_model_18210.4 5 KEGG: 00730+2.2.1.7;MetaCyc: PWY-6892;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6891;MetaCyc: PWY-7560 "Thiamine metabolism";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis II (aerobic bacteria)";"Methylerythritol phosphate pathway II" JAMg_model_20036.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_4767.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444 "EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" JAMg_model_1379.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" JAMg_model_14120.4 11 KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-450302;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-171007 "Relaxin signaling pathway";"Human papillomavirus infection";"activated TAK1 mediates p38 MAPK activation";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"VEGFA-VEGFR2 Pathway";"Human cytomegalovirus infection";"Oxidative Stress Induced Senescence";"p38MAPK events" JAMg_model_19794.1 5 Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-194840 "Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Rho GTPase cycle" JAMg_model_9736.2 2 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" JAMg_model_4541.4 7 Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2" JAMg_model_9669.1 4 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5628897 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination";"TP53 Regulates Metabolic Genes" JAMg_model_14694.3 5 Reactome: R-HSA-5334118;Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-427413 "DNA methylation";"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"NoRC negatively regulates rRNA expression" JAMg_model_10058.2 2 Reactome: R-HSA-6785470;Reactome: R-HSA-6784531 "tRNA processing in the mitochondrion";"tRNA processing in the nucleus" JAMg_model_4541.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320 "AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes" JAMg_model_10328.8 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" JAMg_model_17811.1 1 Reactome: R-HSA-211981 "Xenobiotics" JAMg_model_2615.1 33 MetaCyc: PWY-6871;Reactome: R-HSA-71384;KEGG: 00626+1.1.1.1;MetaCyc: PWY-6313;KEGG: 00625+1.1.1.1;MetaCyc: PWY-5751;MetaCyc: PWY-6333;MetaCyc: PWY-1801;MetaCyc: PWY-6587;MetaCyc: PWY-7396;MetaCyc: PWY-7118;MetaCyc: PWY-5076;MetaCyc: PWY-5057;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5082;KEGG: 00010+1.1.1.1;KEGG: 00680+1.1.1.284;MetaCyc: PWY-7798;MetaCyc: PWY-5486;MetaCyc: PWY-6342;KEGG: 00830+1.1.1.1;KEGG: 00980+1.1.1.1;KEGG: 00982+1.1.1.1;MetaCyc: PWY-5480;MetaCyc: PWY-5079;MetaCyc: PWY-7013;MetaCyc: PWY-7111;KEGG: 00260+1.1.1.1;MetaCyc: PWY-3162;KEGG: 00071+1.1.1.1;KEGG: 00592+1.1.1.1;MetaCyc: PWY-6802;MetaCyc: PWY-5078 "3-methylbutanol biosynthesis (engineered)";"Ethanol oxidation";"Naphthalene degradation";"Serotonin degradation";"Chloroalkane and chloroalkene degradation";"Phenylethanol biosynthesis";"Acetaldehyde biosynthesis I";"Formaldehyde oxidation II (glutathione-dependent)";"Pyruvate fermentation to ethanol III";"Butanol and isobutanol biosynthesis (engineered)";"Chitin degradation to ethanol";"L-leucine degradation III";"L-valine degradation II";"Tyrosine metabolism";"L-methionine degradation III";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Protein S-nitrosylation and denitrosylation";"Pyruvate fermentation to ethanol II";"Noradrenaline and adrenaline degradation";"Retinol metabolism";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"Pyruvate fermentation to ethanol I";"L-phenylalanine degradation III";"(S)-propane-1,2-diol degradation";"Pyruvate fermentation to isobutanol (engineered)";"Glycine, serine and threonine metabolism";"L-tryptophan degradation V (side chain pathway)";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"Salidroside biosynthesis";"L-isoleucine degradation II" JAMg_model_570.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_18830.2 10 MetaCyc: PWY-5757;KEGG: 00440+5.4.2.9;MetaCyc: PWY-6682;MetaCyc: PWY-7510;MetaCyc: PWY-6322;MetaCyc: PWY-7419;MetaCyc: PWY-6839;MetaCyc: PWY-7769;KEGG: 00998+5.4.2.9;MetaCyc: PWY-8067 "Fosfomycin biosynthesis";"Phosphonate and phosphinate metabolism";"Dehydrophos biosynthesis";"Rhizocticin A and B biosynthesis";"Phosphinothricin tripeptide biosynthesis";"FR-900098 and FR-33289 antibiotics biosynthesis";"2-aminoethylphosphonate biosynthesis";"Phosalacine biosynthesis";"Biosynthesis of various secondary metabolites - part 2";"Methylphosphonate biosynthesis" JAMg_model_12827.4 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" JAMg_model_15632.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_2263.1 26 Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-9609736;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-389960;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-389977;Reactome: R-HSA-6811434;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399 "Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Cilium Assembly";"HCMV Early Events";"Mitotic Prometaphase";"Assembly and cell surface presentation of NMDA receptors";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Formation of tubulin folding intermediates by CCT/TriC";"Kinesins";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"Post-chaperonin tubulin folding pathway";"COPI-dependent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Aggrephagy" JAMg_model_6424.1 27 Reactome: R-HSA-159236;Reactome: R-HSA-72203;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-9010553;Reactome: R-HSA-6803529;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-73856;Reactome: R-HSA-111367;Reactome: R-HSA-8851708;Reactome: R-HSA-975957;Reactome: R-HSA-159227;Reactome: R-HSA-72187;Reactome: R-HSA-72165;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-975956;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-159230;Reactome: R-HSA-167200;Reactome: R-HSA-77588;Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-6807505;Reactome: R-HSA-674695 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of expression of SLITs and ROBOs";"FGFR2 alternative splicing";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs";"Signaling by FGFR2 IIIa TM";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of the SLBP independent Mature mRNA";"mRNA 3'-end processing";"mRNA Splicing - Minor Pathway";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"Transport of the SLBP Dependant Mature mRNA";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"snRNP Assembly";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events" JAMg_model_8160.2 12 MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00051+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00030+4.1.2.13;KEGG: 00680+4.1.2.13;KEGG: 00710+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-1861;MetaCyc: PWY-6142 "Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Pentose phosphate pathway";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" JAMg_model_18117.10 12 KEGG: 00270+4.4.1.13;MetaCyc: PWY-2821;MetaCyc: PWY-801;Reactome: R-HSA-71240;MetaCyc: PWY-7901;MetaCyc: PWY-6842;MetaCyc: PWY-601;KEGG: 00380+2.6.1.7;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6309;MetaCyc: PWY-6936;MetaCyc: PWY-1187 "Cysteine and methionine metabolism";"Glucosinolate biosynthesis from phenylalanine";"Homocysteine and cysteine interconversion";"Tryptophan catabolism";"Glucosinolate biosynthesis from tyrosine";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from tryptophan";"Tryptophan metabolism";"Selenocompound metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from homomethionine" JAMg_model_15205.1 4 KEGG: 00513+2.4.1.260;Reactome: R-HSA-4720489;KEGG: 00510+2.4.1.260;Reactome: R-HSA-446193 "Various types of N-glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" JAMg_model_4360.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" JAMg_model_5403.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Peptide chain elongation" JAMg_model_18534.2 5 Reactome: R-HSA-1266695;Reactome: R-HSA-3214858;Reactome: R-HSA-201722;Reactome: R-HSA-3247509;Reactome: R-HSA-8939243 "Interleukin-7 signaling";"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" JAMg_model_2.1 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" JAMg_model_10351.1 3 Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-5362798 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Release of Hh-Np from the secreting cell" JAMg_model_1852.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" JAMg_model_21315.7 15 Reactome: R-HSA-70171;MetaCyc: PWY-7003;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6142;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6901;KEGG: 00010+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-7383;MetaCyc: PWY-7218;MetaCyc: PWY-8004;MetaCyc: PWY-6886;MetaCyc: PWY-2221;MetaCyc: PWY-5723 "Glycolysis";"Glycerol degradation to butanol";"Pyruvate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Purine metabolism";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Rubisco shunt" JAMg_model_20989.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" JAMg_model_1629.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" JAMg_model_5776.5 3 Reactome: R-HSA-1614603;Reactome: R-HSA-1614558;Reactome: R-HSA-2408508 "Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" JAMg_model_886.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" JAMg_model_20250.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" JAMg_model_15441.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" JAMg_model_7685.1 4 MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14 "Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism" JAMg_model_387.1 2 KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Pentose phosphate pathway" JAMg_model_10600.3 14 Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-426496 "Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs" JAMg_model_17561.3 6 Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257 "Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion" JAMg_model_7441.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" JAMg_model_19399.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_11756.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-390918 "Peroxisomal protein import";"Peroxisomal lipid metabolism" JAMg_model_3438.7 3 Reactome: R-HSA-2129379;Reactome: R-HSA-1474228;Reactome: R-HSA-1566948 "Molecules associated with elastic fibres";"Degradation of the extracellular matrix";"Elastic fibre formation" JAMg_model_1031.1 8 Reactome: R-HSA-432040;Reactome: R-HSA-381676;Reactome: R-HSA-164378;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-5610787;Reactome: R-HSA-163615 "Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"Hedgehog 'off' state";"PKA activation" JAMg_model_1931.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" JAMg_model_1565.2 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" JAMg_model_18624.3 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Viral mRNA Translation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression" JAMg_model_19211.1 56 Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-5687128 "Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"UCH proteinases";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"MAPK6/MAPK4 signaling" JAMg_model_1696.1 9 Reactome: R-HSA-69205;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-68952 "G1/S-Specific Transcription";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"Polymerase switching";"Removal of the Flap Intermediate";"DNA replication initiation" JAMg_model_13413.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" JAMg_model_21022.6 13 Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" JAMg_model_4290.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" JAMg_model_19116.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_12320.2 18 MetaCyc: PWY-7205;Reactome: R-HSA-499943;MetaCyc: PWY-6545;MetaCyc: PWY-7221;MetaCyc: PWY-7187;MetaCyc: PWY-7227;MetaCyc: PWY-7176;MetaCyc: PWY-7224;MetaCyc: PWY-7222;MetaCyc: PWY-7210;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7198;MetaCyc: PWY-7226;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7197;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7184 "CMP phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I" JAMg_model_14736.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_8311.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" JAMg_model_21148.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" JAMg_model_15277.3 10 MetaCyc: PWY-1722;MetaCyc: PWY-2201;MetaCyc: PWY-5497;KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;MetaCyc: PWY-6613;MetaCyc: PWY-3841;MetaCyc: PWY-5030;Reactome: R-HSA-196757 "Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations I";"Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Formaldehyde oxidation VII (THF pathway)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations II (plants)";"L-histidine degradation III";"Metabolism of folate and pterines" JAMg_model_322.2 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" JAMg_model_5494.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression" JAMg_model_13226.4 3 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109 "Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis" JAMg_model_12772.2 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" JAMg_model_17867.1 10 MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-8001;MetaCyc: PWY-6842;MetaCyc: PWY-7559;MetaCyc: PWY-4041;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061 "Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I" JAMg_model_9881.4 5 KEGG: 00260+2.3.1.37;KEGG: 00860+2.3.1.37;MetaCyc: PWY-5189;MetaCyc: PWY-7536;Reactome: R-HSA-189451 "Glycine, serine and threonine metabolism";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Heme biosynthesis" JAMg_model_88.1 6 KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817 "Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" JAMg_model_878.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" JAMg_model_17386.1 3 Reactome: R-HSA-8963684;KEGG: 00643+3.7.1.2;KEGG: 00350+3.7.1.2 "Tyrosine catabolism";"Styrene degradation";"Tyrosine metabolism" JAMg_model_5636.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" JAMg_model_19319.1 18 Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-6807505;Reactome: R-HSA-674695 "mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events" JAMg_model_13040.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" JAMg_model_16891.3 1 Reactome: R-HSA-74217 "Purine salvage" JAMg_model_8885.2 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" JAMg_model_13706.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" JAMg_model_9991.2 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" JAMg_model_6002.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" JAMg_model_10017.2 1 Reactome: R-HSA-8874211 "CREB3 factors activate genes" JAMg_model_12173.1 4 Reactome: R-HSA-499943;Reactome: R-HSA-6798695;Reactome: R-HSA-2162123;KEGG: 00590+5.3.99.3 "Interconversion of nucleotide di- and triphosphates";"Neutrophil degranulation";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Arachidonic acid metabolism" JAMg_model_2125.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_4485.5 4 Reactome: R-HSA-5689603;MetaCyc: PWY-7437;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255 "UCH proteinases";"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"Other types of O-glycan biosynthesis" JAMg_model_8611.1 7 Reactome: R-HSA-8964208;KEGG: 00790+1.14.16.1;Reactome: R-HSA-2160456;KEGG: 00400+1.14.16.1;MetaCyc: PWY-7158;MetaCyc: PWY-6134;KEGG: 00360+1.14.16.1 "Phenylalanine metabolism";"Folate biosynthesis";"Phenylketonuria";"Phenylalanine, tyrosine and tryptophan biosynthesis";"L-phenylalanine degradation V";"L-tyrosine biosynthesis IV";"Phenylalanine metabolism" JAMg_model_19116.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_13068.2 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_19983.3 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_602.2 13 Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation";"Viral mRNA Translation" JAMg_model_10947.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" JAMg_model_16886.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" JAMg_model_12703.2 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" JAMg_model_3132.2 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" JAMg_model_13315.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" JAMg_model_19039.2 3 Reactome: R-HSA-110314;MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Recognition of DNA damage by PCNA-containing replication complex";"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" JAMg_model_17000.3 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" JAMg_model_4994.1 2 Reactome: R-HSA-2142850;Reactome: R-HSA-382556 "Hyaluronan biosynthesis and export";"ABC-family proteins mediated transport" JAMg_model_18100.1 1 Reactome: R-HSA-1632852 "Macroautophagy" JAMg_model_997.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" JAMg_model_19199.3 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" JAMg_model_9481.2 8 Reactome: R-HSA-1222556;Reactome: R-HSA-9636467;Reactome: R-HSA-167590;Reactome: R-HSA-983712;Reactome: R-HSA-182218;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "ROS and RNS production in phagocytes";"Blockage of phagosome acidification";"Nef Mediated CD4 Down-regulation";"Ion channel transport";"Nef Mediated CD8 Down-regulation";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling" JAMg_model_6329.1 1 MetaCyc: PWY-7379 "Mrna capping II" JAMg_model_3935.1 1 Reactome: R-HSA-379716 "Cytosolic tRNA aminoacylation" JAMg_model_3475.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" JAMg_model_11878.1 6 Reactome: R-HSA-189085;MetaCyc: PWY-5067;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900 "Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)" JAMg_model_3961.1 3 KEGG: 00310+1.14.11.8;MetaCyc: PWY-6100;Reactome: R-HSA-71262 "Lysine degradation";"L-carnitine biosynthesis";"Carnitine synthesis" JAMg_model_4185.5 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" JAMg_model_18825.1 5 Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-201722;Reactome: R-HSA-112382 "E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the beta-catenin:TCF transactivating complex";"Formation of RNA Pol II elongation complex" JAMg_model_20006.1 5 Reactome: R-HSA-6811438;Reactome: R-HSA-6811434;Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" JAMg_model_8699.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" JAMg_model_10223.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" JAMg_model_16405.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" JAMg_model_17921.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" JAMg_model_10021.8 4 KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841;KEGG: 00053+1.13.99.1;Reactome: R-HSA-1855183 "Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Ascorbate and aldarate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol" JAMg_model_18551.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" JAMg_model_5070.3 17 MetaCyc: PWY-6608;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6627;MetaCyc: PWY-5695;MetaCyc: PWY-6644;MetaCyc: PWY-7179;Reactome: R-HSA-74259;MetaCyc: PWY-6611;KEGG: 00240+2.4.2.1;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;MetaCyc: PWY-4202;MetaCyc: PWY-6620;Reactome: R-HSA-74217;MetaCyc: PWY-5532;Reactome: R-HSA-6798695;KEGG: 00230+2.4.2.1 "Guanosine nucleotides degradation III";"Nicotinate and nicotinamide metabolism";"Salinosporamide A biosynthesis";"Inosine 5'-phosphate degradation";"Fluoroacetate and fluorothreonine biosynthesis";"Purine deoxyribonucleosides degradation I";"Purine catabolism";"Adenine and adenosine salvage V";"Pyrimidine metabolism";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Arsenate detoxification I (mammalian)";"Guanine and guanosine salvage";"Purine salvage";"Nucleoside and nucleotide degradation (archaea)";"Neutrophil degranulation";"Purine metabolism" JAMg_model_393.2 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_3598.1 1 Reactome: R-HSA-70350 "Fructose catabolism" JAMg_model_14545.1 70 KEGG: 00564+2.3.1.51;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-174154;MetaCyc: PWY-5667;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;MetaCyc: PWY-8053;MetaCyc: PWY-7589;MetaCyc: PWY-7411;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;MetaCyc: PWY-7782;Reactome: R-HSA-4641258;MetaCyc: PWY-7587;Reactome: R-HSA-180585;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-4641257;Reactome: R-HSA-1483166;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;MetaCyc: PWY-5981;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-68949;MetaCyc: PWY-8051;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-382556;MetaCyc: PWY-8055;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;MetaCyc: PWY-6453;Reactome: R-HSA-1234176;MetaCyc: PWY-7417;Reactome: R-HSA-5689603;KEGG: 00561+2.3.1.51;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-69017 "Glycerophospholipid metabolism";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"APC/C:Cdc20 mediated degradation of Securin";"CDP-diacylglycerol biosynthesis I";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Anandamide biosynthesis II";"Palmitoleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"G2/M Checkpoints";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Plasmalogen biosynthesis";"Degradation of DVL";"Oleate biosynthesis III (cyanobacteria)";"Vif-mediated degradation of APOBEC3G";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of AXIN";"Synthesis of PA";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDP-diacylglycerol biosynthesis III";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Anandamide biosynthesis I";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Palmitoyl ethanolamide biosynthesis";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Stigma estolide biosynthesis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Phospholipid remodeling (phosphatidate, yeast)";"UCH proteinases";"Glycerolipid metabolism";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6" JAMg_model_17255.1 3 MetaCyc: PWY-7833;Reactome: R-HSA-9033807;MetaCyc: PWY-7831 "Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide" JAMg_model_18152.3 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_14135.1 27 Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-168333 "NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery" JAMg_model_21100.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_7657.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" JAMg_model_14961.3 4 MetaCyc: PWY-6987;MetaCyc: PWY-7382;Reactome: R-HSA-389661;KEGG: 00785+2.8.1.8 "Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism" JAMg_model_15505.4 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" JAMg_model_19885.2 2 Reactome: R-HSA-1236974;Reactome: R-HSA-1799339 "ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane" JAMg_model_5588.3 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" JAMg_model_19533.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_6438.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" JAMg_model_13400.1 10 Reactome: R-HSA-2565942;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-5684264;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091 "Regulation of PLK1 Activity at G2/M Transition";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Neddylation";"Activation of NF-kappaB in B cells" JAMg_model_8065.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_5232.2 1 Reactome: R-HSA-5620924 "Intraflagellar transport" JAMg_model_8445.1 5 Reactome: R-HSA-5696397;Reactome: R-HSA-110381;Reactome: R-HSA-6782210;Reactome: R-HSA-5685939;Reactome: R-HSA-5649702 "Gap-filling DNA repair synthesis and ligation in GG-NER";"Resolution of AP sites via the single-nucleotide replacement pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through MMEJ (alt-NHEJ)";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" JAMg_model_18999.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-6791226 "L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_2770.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" JAMg_model_14956.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-68875 "Recruitment of NuMA to mitotic centrosomes";"Mitotic Prophase" JAMg_model_15097.4 8 Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-182218;Reactome: R-HSA-9636467;Reactome: R-HSA-1222556;Reactome: R-HSA-167590 "Transferrin endocytosis and recycling";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Nef Mediated CD8 Down-regulation";"Blockage of phagosome acidification";"ROS and RNS production in phagocytes";"Nef Mediated CD4 Down-regulation" JAMg_model_5262.4 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" JAMg_model_10182.3 5 Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-983231;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Factors involved in megakaryocyte development and platelet production";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic" JAMg_model_8068.1 3 Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.25;Reactome: R-HSA-8853383 "Neutrophil degranulation";"Other glycan degradation";"Lysosomal oligosaccharide catabolism" JAMg_model_13201.1 9 Reactome: R-HSA-2022928;Reactome: R-HSA-2024096;Reactome: R-HSA-3560783;Reactome: R-HSA-1971475;Reactome: R-HSA-975634;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-4420332;Reactome: R-HSA-3656253 "HS-GAG biosynthesis";"HS-GAG degradation";"Defective B4GALT7 causes EDS, progeroid type";"A tetrasaccharide linker sequence is required for GAG synthesis";"Retinoid metabolism and transport";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS" JAMg_model_20559.1 1 Reactome: R-HSA-1368108 "BMAL1:CLOCK,NPAS2 activates circadian gene expression" JAMg_model_2154.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" JAMg_model_12643.1 14 Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-426486;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723 "Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Small interfering RNA (siRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation" JAMg_model_9895.4 10 MetaCyc: PWY-3821;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-7344;MetaCyc: PWY-6317;Reactome: R-HSA-5609977;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7328;Reactome: R-HSA-70370;MetaCyc: PWY-6397 "D-galactose detoxification";"Galactose metabolism";"Stachyose degradation";"UDP-alpha-D-galactose biosynthesis";"D-galactose degradation I (Leloir pathway)";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Amino sugar and nucleotide sugar metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose catabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis" JAMg_model_17785.9 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" JAMg_model_6816.2 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" JAMg_model_10096.2 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_3209.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" JAMg_model_11689.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" JAMg_model_10417.5 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" JAMg_model_6324.1 10 MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;KEGG: 00564+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-8055 "Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Synthesis of PA";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis" JAMg_model_8151.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" JAMg_model_2091.1 5 Reactome: R-HSA-73817;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6277;MetaCyc: PWY-6122;MetaCyc: PWY-6121 "Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I" JAMg_model_12979.2 18 MetaCyc: PWY-7226;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7197;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7210;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7198;MetaCyc: PWY-7227;MetaCyc: PWY-7222;MetaCyc: PWY-7224;MetaCyc: PWY-7176;MetaCyc: PWY-6545;Reactome: R-HSA-499943;MetaCyc: PWY-7205;MetaCyc: PWY-7221;MetaCyc: PWY-7187 "Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"CMP phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II" JAMg_model_9696.2 27 Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377 "SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins" JAMg_model_7088.3 3 Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369 "Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis" JAMg_model_2984.1 9 Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568 "G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates" JAMg_model_19820.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_15011.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_8896.1 12 Reactome: R-HSA-2644606;Reactome: R-HSA-982772;Reactome: R-HSA-5362798;Reactome: R-HSA-75893;Reactome: R-HSA-2691232;Reactome: R-HSA-177929;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-193692;Reactome: R-HSA-1251985;Reactome: R-HSA-2660826;Reactome: R-HSA-1442490 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Growth hormone receptor signaling";"Release of Hh-Np from the secreting cell";"TNF signaling";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Signaling by EGFR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulated proteolysis of p75NTR";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Collagen degradation" JAMg_model_1523.7 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8949613 "Mitochondrial protein import";"Cristae formation" JAMg_model_3539.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" JAMg_model_21022.7 13 Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Peptide chain elongation" JAMg_model_14776.2 2 Reactome: R-HSA-8983711;Reactome: R-HSA-909733 "OAS antiviral response";"Interferon alpha/beta signaling" JAMg_model_2380.1 19 Reactome: R-HSA-9649948;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-442982 "Signaling downstream of RAS mutants";"RAF/MAP kinase cascade";"Long-term potentiation";"Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"RAF activation";"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"Ion homeostasis";"Ion transport by P-type ATPases";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor" JAMg_model_7159.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" JAMg_model_20443.2 5 KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403 "Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Ophthalmate biosynthesis";"Glutathione metabolism";"Glutathione synthesis and recycling" JAMg_model_21253.1 7 Reactome: R-HSA-72702;Reactome: R-HSA-72662;Reactome: R-HSA-429947;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-166208;Reactome: R-HSA-72649 "Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Deadenylation of mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"mTORC1-mediated signalling";"Translation initiation complex formation" JAMg_model_340.4 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" JAMg_model_13230.4 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" JAMg_model_21260.3 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" JAMg_model_5070.1 17 MetaCyc: PWY-5695;MetaCyc: PWY-6608;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6627;MetaCyc: PWY-6644;Reactome: R-HSA-74259;MetaCyc: PWY-7179;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6611;MetaCyc: PWY-7179-1;MetaCyc: PWY-4202;MetaCyc: PWY-6609;MetaCyc: PWY-6620;MetaCyc: PWY-5532;Reactome: R-HSA-74217;KEGG: 00230+2.4.2.1;Reactome: R-HSA-6798695 "Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation III";"Nicotinate and nicotinamide metabolism";"Salinosporamide A biosynthesis";"Fluoroacetate and fluorothreonine biosynthesis";"Purine catabolism";"Purine deoxyribonucleosides degradation I";"Pyrimidine metabolism";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation II";"Arsenate detoxification I (mammalian)";"Adenine and adenosine salvage III";"Guanine and guanosine salvage";"Nucleoside and nucleotide degradation (archaea)";"Purine salvage";"Purine metabolism";"Neutrophil degranulation" JAMg_model_18309.1 18 MetaCyc: PWY-7221;MetaCyc: PWY-7187;MetaCyc: PWY-7205;Reactome: R-HSA-499943;MetaCyc: PWY-6545;MetaCyc: PWY-7176;MetaCyc: PWY-7222;MetaCyc: PWY-7224;MetaCyc: PWY-7227;MetaCyc: PWY-7220;MetaCyc: PWY-7198;MetaCyc: PWY-7210;KEGG: 00240+2.7.4.6;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7197;MetaCyc: PWY-7184;MetaCyc: PWY-7226;KEGG: 00230+2.7.4.6 "Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism" JAMg_model_4966.1 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" JAMg_model_11819.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" JAMg_model_11200.2 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" JAMg_model_2700.1 14 Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121;Reactome: R-HSA-5685942;Reactome: R-HSA-174411 "Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Dual incision in TC-NER";"Polymerase switching";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere" JAMg_model_317.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_12319.1 19 MetaCyc: PWY-6545;MetaCyc: PWY-7205;MetaCyc: PWY-7221;MetaCyc: PWY-7187;Reactome: R-HSA-380270;MetaCyc: PWY-7227;MetaCyc: PWY-7224;MetaCyc: PWY-7222;MetaCyc: PWY-7176;MetaCyc: PWY-7210;KEGG: 00240+2.7.4.6;Reactome: R-HSA-380320;MetaCyc: PWY-7198;MetaCyc: PWY-7220;MetaCyc: PWY-7226;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7184;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7197 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"CMP phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Recruitment of mitotic centrosome proteins and complexes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Recruitment of NuMA to mitotic centrosomes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotide phosphorylation" JAMg_model_3080.2 7 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection" JAMg_model_14261.4 3 MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17 "Folate polyglutamylation";"Metabolism of folate and pterines";"Folate biosynthesis" JAMg_model_9755.2 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" JAMg_model_4464.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" JAMg_model_11978.3 2 Reactome: R-HSA-5689880;MetaCyc: PWY-7511 "Ub-specific processing proteases";"Protein ubiquitination" JAMg_model_18221.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" JAMg_model_5394.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" JAMg_model_17281.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_8164.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" JAMg_model_15470.1 57 Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-174178 "Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FCERI mediated NF-kB activation";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" JAMg_model_15595.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" JAMg_model_16400.2 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" JAMg_model_16169.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" JAMg_model_11779.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" JAMg_model_9063.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" JAMg_model_19661.1 13 Reactome: R-HSA-156590;MetaCyc: PWY-6842;MetaCyc: PWY-7112;KEGG: 00053+1.8.5.1;KEGG: 00983+2.5.1.18;MetaCyc: PWY-2261;MetaCyc: PWY-4061;MetaCyc: PWY-7533;KEGG: 00480+2.5.1.18+1.8.5.1;Reactome: R-HSA-196836;KEGG: 00980+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6370 "Glutathione conjugation";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Ascorbate and aldarate metabolism";"Drug metabolism - other enzymes";"Ascorbate glutathione cycle";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Glutathione metabolism";"Vitamin C (ascorbate) metabolism";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"Ascorbate recycling (cytosolic)" JAMg_model_8702.4 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" JAMg_model_1113.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" JAMg_model_20392.1 4 Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169 "Translesion synthesis by POLK";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis" JAMg_model_13475.1 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_7757.2 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" JAMg_model_4116.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" JAMg_model_9047.2 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_16767.2 2 Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14 "Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms" JAMg_model_12880.2 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" JAMg_model_2301.1 1 Reactome: R-HSA-1632852 "Macroautophagy" JAMg_model_9243.2 1 Reactome: R-HSA-6785631 "ERBB2 Regulates Cell Motility" JAMg_model_15097.5 8 Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-167590;Reactome: R-HSA-9636467;Reactome: R-HSA-1222556;Reactome: R-HSA-182218;Reactome: R-HSA-983712 "Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Nef Mediated CD4 Down-regulation";"Blockage of phagosome acidification";"ROS and RNS production in phagocytes";"Nef Mediated CD8 Down-regulation";"Ion channel transport" JAMg_model_17901.2 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" JAMg_model_2842.3 17 Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-983168;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Antigen processing: Ubiquitination & Proteasome degradation";"Peptide chain elongation";"Viral mRNA Translation" JAMg_model_8006.1 10 Reactome: R-HSA-4719360;KEGG: 00510+2.4.1.83;MetaCyc: PWY-7922;Reactome: R-HSA-162699;MetaCyc: PWY-7661;Reactome: R-HSA-4719377;Reactome: R-HSA-4717374;MetaCyc: PWY-7921;Reactome: R-HSA-913709;MetaCyc: PWY-7979 "Defective DPM3 causes DPM3-CDG (CDG-1o)";"N-Glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Synthesis of dolichyl-phosphate mannose";"Protein N-glycosylation (Haloferax volcanii)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Protein O-mannosylation I (yeast)";"O-linked glycosylation of mucins";"Protein O-mannosylation III (mammals, core M3)" JAMg_model_5689.4 2 Reactome: R-HSA-6807505;Reactome: R-HSA-191859 "RNA polymerase II transcribes snRNA genes";"snRNP Assembly" JAMg_model_4501.1 16 Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-201722;Reactome: R-HSA-5693548;Reactome: R-HSA-9018519;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693571;Reactome: R-HSA-3214847;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-2559586;Reactome: R-HSA-5693579;Reactome: R-HSA-5693565 "Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Formation of the beta-catenin:TCF transactivating complex";"Sensing of DNA Double Strand Breaks";"Estrogen-dependent gene expression";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Nonhomologous End-Joining (NHEJ)";"HATs acetylate histones";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"DNA Damage/Telomere Stress Induced Senescence";"Homologous DNA Pairing and Strand Exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" JAMg_model_17520.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_440.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" JAMg_model_13352.2 24 Reactome: R-HSA-400042;Reactome: R-HSA-416482;Reactome: R-HSA-202040;Reactome: R-HSA-500657;Reactome: R-HSA-418555;Reactome: R-HSA-392451;Reactome: R-HSA-6814122;Reactome: R-HSA-416476;Reactome: R-HSA-8964315;Reactome: R-HSA-8964616;Reactome: R-HSA-420092;Reactome: R-HSA-418597;Reactome: R-HSA-9009391;Reactome: R-HSA-392851;Reactome: R-HSA-4086398;Reactome: R-HSA-392170;Reactome: R-HSA-418217;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-381676;Reactome: R-HSA-428930;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-418594 "Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (12/13) signalling events";"G-protein activation";"Presynaptic function of Kainate receptors";"G alpha (s) signalling events";"G beta:gamma signalling through PI3Kgamma";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (q) signalling events";"G beta:gamma signalling through BTK";"G beta:gamma signalling through CDC42";"Glucagon-type ligand receptors";"G alpha (z) signalling events";"Extra-nuclear estrogen signaling";"Prostacyclin signalling through prostacyclin receptor";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thromboxane signalling through TP receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events" JAMg_model_18100.5 1 Reactome: R-HSA-1632852 "Macroautophagy" JAMg_model_17352.1 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" JAMg_model_3036.1 6 Reactome: R-HSA-9010553;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" JAMg_model_15859.1 4 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer" JAMg_model_17038.1 2 KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" JAMg_model_17564.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912 "Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane" JAMg_model_3264.2 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" JAMg_model_17319.3 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" JAMg_model_7288.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" JAMg_model_8910.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" JAMg_model_2935.1 2 Reactome: R-HSA-419812;Reactome: R-HSA-418555 "Calcitonin-like ligand receptors";"G alpha (s) signalling events" JAMg_model_326.4 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_650.6 4 KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202 "Glutathione metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines" JAMg_model_3325.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" JAMg_model_1911.1 7 KEGG: 00010+1.2.4.1;Reactome: R-HSA-204174;Reactome: R-HSA-5362517;KEGG: 00620+1.2.4.1;Reactome: R-HSA-389661;Reactome: R-HSA-70268;KEGG: 00020+1.2.4.1 "Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Citrate cycle (TCA cycle)" JAMg_model_2059.7 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" JAMg_model_12590.1 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_17734.8 5 Reactome: R-HSA-6798695;MetaCyc: PWY-5188;KEGG: 00860+4.2.1.24;Reactome: R-HSA-189451;MetaCyc: PWY-5189 "Neutrophil degranulation";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)" JAMg_model_7911.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" JAMg_model_10854.1 6 Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693607 "HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends" JAMg_model_8808.2 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" JAMg_model_15311.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_16579.2 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_175.1 6 Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-427359;Reactome: R-HSA-427413 "RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression" JAMg_model_14911.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" JAMg_model_3715.4 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_5566.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706 "Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit" JAMg_model_19969.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_11569.1 4 Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695 "COPII-mediated vesicle transport";"Cargo concentration in the ER";"MHC class II antigen presentation";"Neutrophil degranulation" JAMg_model_3885.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" JAMg_model_11741.3 24 Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-9609736;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-5617833 "Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Aggrephagy";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"HCMV Early Events";"Mitotic Prometaphase";"Assembly and cell surface presentation of NMDA receptors";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly" JAMg_model_7496.2 4 Reactome: R-HSA-982772;Reactome: R-HSA-1170546;Reactome: R-HSA-983231;Reactome: R-HSA-2586552 "Growth hormone receptor signaling";"Prolactin receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin" JAMg_model_19027.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_12281.5 2 Reactome: R-HSA-5205685;Reactome: R-HSA-983231 "Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production" JAMg_model_13143.1 3 MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21 "Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system" JAMg_model_8762.2 7 Reactome: R-HSA-201688;Reactome: R-HSA-4641258;Reactome: R-HSA-4086400;Reactome: R-HSA-5368598;Reactome: R-HSA-201681;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262 "WNT mediated activation of DVL";"Degradation of DVL";"PCP/CE pathway";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"TCF dependent signaling in response to WNT";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane" JAMg_model_8702.3 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" JAMg_model_8327.1 17 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-6790901;Reactome: R-HSA-975956 "Peptide chain elongation";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" JAMg_model_14505.3 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" JAMg_model_13710.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination" JAMg_model_14184.3 3 MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106 "Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)" JAMg_model_14217.1 4 MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614 "Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine salvage" JAMg_model_8384.2 4 Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic" JAMg_model_20097.1 26 Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-389960;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-8955332 "Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Cilium Assembly";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Formation of tubulin folding intermediates by CCT/TriC";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"HCMV Early Events";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"Carboxyterminal post-translational modifications of tubulin" JAMg_model_4235.3 6 KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23 "Galactose metabolism";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation" JAMg_model_4455.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" JAMg_model_8626.1 2 MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4 "Cellulose degradation II (fungi)";"Starch and sucrose metabolism" JAMg_model_19848.1 9 KEGG: 00960+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00360+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00400+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00350+2.6.1.5 "Tropane, piperidine and pyridine alkaloid biosynthesis";"Cysteine and methionine metabolism";"Isoquinoline alkaloid biosynthesis";"Phenylalanine metabolism";"Tyrosine catabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Novobiocin biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Tyrosine metabolism" JAMg_model_6953.2 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_11739.3 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_16579.4 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_7424.2 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_7784.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_11895.6 5 MetaCyc: PWY-7159;MetaCyc: PWY-5531;KEGG: 00860+4.1.1.37;Reactome: R-HSA-189451;MetaCyc: PWY-7766 "3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Heme b biosynthesis IV (Gram-positive bacteria)" JAMg_model_20334.5 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" JAMg_model_6360.2 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" JAMg_model_4185.8 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" JAMg_model_11890.1 4 Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695 "COPII-mediated vesicle transport";"Cargo concentration in the ER";"MHC class II antigen presentation";"Neutrophil degranulation" JAMg_model_13517.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" JAMg_model_10246.2 13 KEGG: 00604+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2022857 "Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Keratan sulfate degradation" JAMg_model_17775.5 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" JAMg_model_19716.1 5 MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109 "Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis" JAMg_model_2773.1 4 KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3 "Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism" JAMg_model_359.5 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" JAMg_model_11252.7 9 MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.94;KEGG: 00564+1.1.1.8;MetaCyc: PWY-5981;MetaCyc: PWY-6118;MetaCyc: PWY-7902;MetaCyc: PWY-5667 "Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Glycerol-3-phosphate shuttle";"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis I" JAMg_model_7638.3 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_9707.1 4 Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-400511 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)" JAMg_model_21267.2 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" JAMg_model_8310.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" JAMg_model_5367.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" JAMg_model_9208.1 16 Reactome: R-HSA-179409;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-2559582 "APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)" JAMg_model_1359.3 12 Reactome: R-HSA-416482;KEGG: 05170+2.7.11.1;Reactome: R-HSA-418885;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-193648;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1 "G alpha (12/13) signalling events";"Human immunodeficiency virus 1 infection";"DCC mediated attractive signaling";"Human cytomegalovirus infection";"Thermogenesis";"Rho GTPase cycle";"Human papillomavirus infection";"G alpha (q) signalling events";"NRAGE signals death through JNK";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway" JAMg_model_11589.1 5 MetaCyc: PWY-5667;MetaCyc: PWY-7817;KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5981 "CDP-diacylglycerol biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis III" JAMg_model_14925.2 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" JAMg_model_7451.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis" JAMg_model_8392.1 2 Reactome: R-HSA-111458;Reactome: R-HSA-9627069 "Formation of apoptosome";"Regulation of the apoptosome activity" JAMg_model_9210.2 8 Reactome: R-HSA-1445148;Reactome: R-HSA-9613354;Reactome: R-HSA-2151209;Reactome: R-HSA-1632852;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-9619483 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Macroautophagy";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Activation of AMPK downstream of NMDARs" JAMg_model_16722.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_2657.2 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_11694.4 11 Reactome: R-HSA-983231;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5693565;Reactome: R-HSA-69231;Reactome: R-HSA-8940973;Reactome: R-HSA-8939236;Reactome: R-HSA-5685938;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-428890;Reactome: R-HSA-525793 "Factors involved in megakaryocyte development and platelet production";"T cell receptor signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cyclin D associated events in G1";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDR through Single Strand Annealing (SSA)";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Role of ABL in ROBO-SLIT signaling";"Myogenesis" JAMg_model_1988.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" JAMg_model_574.2 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_15999.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" JAMg_model_1523.6 2 Reactome: R-HSA-8949613;Reactome: R-HSA-1268020 "Cristae formation";"Mitochondrial protein import" JAMg_model_5303.4 4 MetaCyc: PWY-6129;KEGG: 00510+2.7.1.108;Reactome: R-HSA-4755583;Reactome: R-HSA-446199 "Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis";"Defective DOLK causes DOLK-CDG (CDG-1m)";"Synthesis of Dolichyl-phosphate" JAMg_model_16456.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" JAMg_model_1876.1 11 Reactome: R-HSA-2219530;Reactome: R-HSA-6785631;Reactome: R-HSA-1963642;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001;Reactome: R-HSA-1250196;Reactome: R-HSA-8863795;Reactome: R-HSA-1227986;Reactome: R-HSA-9664565;Reactome: R-HSA-8847993 "Constitutive Signaling by Aberrant PI3K in Cancer";"ERBB2 Regulates Cell Motility";"PI3K events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade";"SHC1 events in ERBB2 signaling";"Downregulation of ERBB2 signaling";"Signaling by ERBB2";"Signaling by ERBB2 KD Mutants";"ERBB2 Activates PTK6 Signaling" JAMg_model_1909.7 1 Reactome: R-HSA-8949664 "Processing of SMDT1" JAMg_model_1520.3 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" JAMg_model_10182.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-983231 "MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Factors involved in megakaryocyte development and platelet production" JAMg_model_10811.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" JAMg_model_11556.2 15 Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-8936459;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-2559580;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585 "Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence" JAMg_model_561.2 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_969.1 4 KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.17 "Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" JAMg_model_1630.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_8695.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" JAMg_model_13292.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" JAMg_model_12508.3 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" JAMg_model_2753.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_2603.2 10 MetaCyc: PWY-1861;KEGG: 00680+2.7.1.11;KEGG: 00051+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00030+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00052+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-1042 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Methane metabolism";"Fructose and mannose metabolism";"Glycolysis";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)" JAMg_model_15542.1 31 MetaCyc: PWY-6799;MetaCyc: PWY-8012;MetaCyc: PWY-6519;Reactome: R-HSA-2426168;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-4381;MetaCyc: PWY-6282;MetaCyc: PWY-6113;MetaCyc: PWY-7664;MetaCyc: PWY-5966-1;Reactome: R-HSA-75105;MetaCyc: PWY-5973;MetaCyc: PWY-5147;MetaCyc: PWY-5989;Reactome: R-HSA-9029558;MetaCyc: PWY-5142;Reactome: R-HSA-163765;MetaCyc: PWY-5971;MetaCyc: PWY-8049;MetaCyc: PWY-8047;MetaCyc: PWY-7858;MetaCyc: PWY-5994;Reactome: R-HSA-199220;MetaCyc: PWY-5366;MetaCyc: PWY-7388;MetaCyc: PWY-7723;MetaCyc: PWY-7663;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWYG-321;MetaCyc: PWY-5367;MetaCyc: PWY-7746 "Fatty acid biosynthesis initiation (plant mitochondria)";"Mupirocin biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Activation of gene expression by SREBF (SREBP)";"Biotin metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Superpathway of mycolate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acyl-CoA biosynthesis";"Cis-vaccenate biosynthesis";"Oleate biosynthesis I (plants)";"Stearate biosynthesis II (bacteria and plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"ChREBP activates metabolic gene expression";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Pederin biosynthesis";"Bryostatin biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"Palmitoleate biosynthesis II (plants and bacteria)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Bacterial bioluminescence";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis";"";"Petroselinate biosynthesis";"Mycobacterial sulfolipid biosynthesis" JAMg_model_197.1 29 Reactome: R-HSA-427413;Reactome: R-HSA-167160;Reactome: R-HSA-5696400;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-674695;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-5696395;Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-6781823;Reactome: R-HSA-73863 "NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual Incision in GG-NER";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Termination" JAMg_model_11389.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" JAMg_model_5184.2 2 Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" JAMg_model_5232.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" JAMg_model_13265.1 7 MetaCyc: PWY-7219;Reactome: R-HSA-73817;MetaCyc: PWY-7234;KEGG: 00250+4.3.2.2;MetaCyc: PWY-6123;KEGG: 00230+4.3.2.2;MetaCyc: PWY-6124 "Adenosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II" JAMg_model_4301.1 8 MetaCyc: PWY-5481;Reactome: R-HSA-70268;KEGG: 00010+1.1.1.27;MetaCyc: PWY-8086;KEGG: 00620+1.1.1.27;KEGG: 00640+1.1.1.27;MetaCyc: PWY-6901;KEGG: 00270+1.1.1.27 "Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Propanoate metabolism";"Superpathway of glucose and xylose degradation";"Cysteine and methionine metabolism" JAMg_model_18834.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" JAMg_model_9194.5 6 KEGG: 00670+2.1.2.3;MetaCyc: PWY-7234;Reactome: R-HSA-73817;KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-6123;MetaCyc: PWY-6124 "One carbon pool by folate";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II" JAMg_model_16066.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_19376.3 5 Reactome: R-HSA-5334118;Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-427413 "DNA methylation";"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"NoRC negatively regulates rRNA expression" JAMg_model_4950.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" JAMg_model_19864.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" JAMg_model_1010.2 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" JAMg_model_3175.1 2 Reactome: R-HSA-6807004;Reactome: R-HSA-877312 "Negative regulation of MET activity";"Regulation of IFNG signaling" JAMg_model_18699.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" JAMg_model_3201.2 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_3560.1 4 MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14 "Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism" JAMg_model_17785.8 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" JAMg_model_19719.1 59 Reactome: R-HSA-1236978;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-350562;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-611105;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-6798695;Reactome: R-HSA-1169091;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-5628897;Reactome: R-HSA-983168 "Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of ornithine decarboxylase (ODC)";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Respiratory electron transport";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Neutrophil degranulation";"Activation of NF-kappaB in B cells";"UCH proteinases";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"TP53 Regulates Metabolic Genes";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_6589.6 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" JAMg_model_13391.2 13 Reactome: R-HSA-114508;Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-139853;Reactome: R-HSA-2029485;Reactome: R-HSA-5578775;Reactome: R-HSA-2871809;Reactome: R-HSA-5607763;Reactome: R-HSA-4086398;Reactome: R-HSA-381676;Reactome: R-HSA-422356;Reactome: R-HSA-1489509;Reactome: R-HSA-5218921 "Effects of PIP2 hydrolysis";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Elevation of cytosolic Ca2+ levels";"Role of phospholipids in phagocytosis";"Ion homeostasis";"FCERI mediated Ca+2 mobilization";"CLEC7A (Dectin-1) induces NFAT activation";"Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Regulation of insulin secretion";"DAG and IP3 signaling";"VEGFR2 mediated cell proliferation" JAMg_model_21063.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" JAMg_model_15875.2 1 Reactome: R-HSA-8949613 "Cristae formation" JAMg_model_9597.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" JAMg_model_4165.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" JAMg_model_2357.1 30 KEGG: 05163+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-211163;Reactome: R-HSA-6804758;Reactome: R-HSA-1358803;Reactome: R-HSA-389357;KEGG: 05170+2.7.11.1;Reactome: R-HSA-111447;Reactome: R-HSA-199418;Reactome: R-HSA-198693;Reactome: R-HSA-9634638;Reactome: R-HSA-8941332;Reactome: R-HSA-5218920;Reactome: R-HSA-392451;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-69656;Reactome: R-HSA-198323;Reactome: R-HSA-8948751;Reactome: R-HSA-69202;Reactome: R-HSA-1257604;Reactome: R-HSA-9614399;Reactome: R-HSA-6804759;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-389513;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-8876198 "Human cytomegalovirus infection";"TP53 Regulates Metabolic Genes";"AKT-mediated inactivation of FOXO1A";"Regulation of TP53 Activity through Acetylation";"Downregulation of ERBB2:ERBB3 signaling";"CD28 dependent PI3K/Akt signaling";"Human immunodeficiency virus 1 infection";"Activation of BAD and translocation to mitochondria";"Negative regulation of the PI3K/AKT network";"AKT phosphorylates targets in the nucleus";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RUNX2 regulates genes involved in cell migration";"VEGFR2 mediated vascular permeability";"G beta:gamma signalling through PI3Kgamma";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Regulation of TP53 Degradation";"Cyclin A:Cdk2-associated events at S phase entry";"AKT phosphorylates targets in the cytosol";"Regulation of PTEN stability and activity";"Cyclin E associated events during G1/S transition";"PIP3 activates AKT signaling";"Regulation of localization of FOXO transcription factors";"Regulation of TP53 Activity through Association with Co-factors";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"CTLA4 inhibitory signaling";"Relaxin signaling pathway";"Human papillomavirus infection";"RAB GEFs exchange GTP for GDP on RABs" JAMg_model_2280.2 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" JAMg_model_14158.1 6 Reactome: R-HSA-975634;Reactome: R-HSA-3000171;Reactome: R-HSA-6798695;Reactome: R-HSA-2453864;Reactome: R-HSA-2453902;Reactome: R-HSA-977225 "Retinoid metabolism and transport";"Non-integrin membrane-ECM interactions";"Neutrophil degranulation";"Retinoid cycle disease events";"The canonical retinoid cycle in rods (twilight vision)";"Amyloid fiber formation" JAMg_model_9039.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" JAMg_model_16872.1 3 Reactome: R-HSA-429947;Reactome: R-HSA-380994;Reactome: R-HSA-450604 "Deadenylation of mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA" JAMg_model_7825.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" JAMg_model_10263.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" JAMg_model_6793.2 6 Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-9640463;Reactome: R-HSA-9029558 "ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Wax biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis" JAMg_model_6375.7 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_18048.2 5 Reactome: R-HSA-70171;MetaCyc: PWY-5514;MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855 "Glycolysis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)" JAMg_model_19002.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_2132.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" JAMg_model_3077.2 33 Reactome: R-HSA-69202;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167162;Reactome: R-HSA-69231;Reactome: R-HSA-167200;Reactome: R-HSA-5696395;Reactome: R-HSA-6796648;Reactome: R-HSA-73762;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-6782135;Reactome: R-HSA-69656;Reactome: R-HSA-6781823;Reactome: R-HSA-73863;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-167172;Reactome: R-HSA-8939236;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-69273;Reactome: R-HSA-427413;Reactome: R-HSA-167160 "Cyclin E associated events during G1/S transition";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Cyclin D associated events in G1";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of Incision Complex in GG-NER";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"Dual incision in TC-NER";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Termination";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"Transcription of the HIV genome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Cyclin A/B1/B2 associated events during G2/M transition";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection" JAMg_model_218.1 4 KEGG: 00910+1.4.1.14;MetaCyc: PWY-6963;KEGG: 00250+1.4.1.14;Reactome: R-HSA-73621 "Nitrogen metabolism";"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"Pyrimidine catabolism" JAMg_model_9101.1 9 Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends" JAMg_model_5433.4 4 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport" JAMg_model_12919.2 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_20983.1 4 Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"ECM proteoglycans";"MET activates PTK2 signaling";"Laminin interactions" JAMg_model_3232.1 4 Reactome: R-HSA-352230;Reactome: R-HSA-5660862;Reactome: R-HSA-210991;Reactome: R-HSA-71240 "Amino acid transport across the plasma membrane";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Basigin interactions";"Tryptophan catabolism" JAMg_model_10892.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" JAMg_model_15466.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" JAMg_model_13503.4 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" JAMg_model_13393.1 13 Reactome: R-HSA-2029485;Reactome: R-HSA-2871809;Reactome: R-HSA-5578775;Reactome: R-HSA-5607763;Reactome: R-HSA-4086398;Reactome: R-HSA-114508;Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-139853;Reactome: R-HSA-1489509;Reactome: R-HSA-5218921;Reactome: R-HSA-381676;Reactome: R-HSA-422356 "Role of phospholipids in phagocytosis";"FCERI mediated Ca+2 mobilization";"Ion homeostasis";"CLEC7A (Dectin-1) induces NFAT activation";"Ca2+ pathway";"Effects of PIP2 hydrolysis";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Elevation of cytosolic Ca2+ levels";"DAG and IP3 signaling";"VEGFR2 mediated cell proliferation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Regulation of insulin secretion" JAMg_model_7564.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" JAMg_model_3500.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" JAMg_model_8371.2 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" JAMg_model_957.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases activate KTN1" JAMg_model_14799.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" JAMg_model_16335.1 1 Reactome: R-HSA-8964572 "Lipid particle organization" JAMg_model_4455.2 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" JAMg_model_4381.1 5 Reactome: R-HSA-6783310;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400 "Fanconi Anemia Pathway";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER" JAMg_model_4083.2 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" JAMg_model_19907.2 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" JAMg_model_1770.3 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" JAMg_model_3899.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" JAMg_model_361.3 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" JAMg_model_2486.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" JAMg_model_18749.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" JAMg_model_16566.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_8910.9 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" JAMg_model_12313.2 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" JAMg_model_9854.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691 "Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" JAMg_model_15980.1 10 Reactome: R-HSA-111459;Reactome: R-HSA-5628897;Reactome: R-HSA-111457;Reactome: R-HSA-2151201;Reactome: R-HSA-9627069;Reactome: R-HSA-611105;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-111458;Reactome: R-HSA-3299685 "Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Metabolic Genes";"Release of apoptotic factors from the mitochondria";"Transcriptional activation of mitochondrial biogenesis";"Regulation of the apoptosome activity";"Respiratory electron transport";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome";"Detoxification of Reactive Oxygen Species" JAMg_model_390.1 3 Reactome: R-HSA-5250924;Reactome: R-HSA-72163;Reactome: R-HSA-72165 "B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" JAMg_model_10357.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-432722;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440 "Neutrophil degranulation";"Golgi Associated Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network" JAMg_model_17664.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" JAMg_model_2102.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553 "Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Viral mRNA Translation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs" JAMg_model_5960.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" JAMg_model_19039.3 3 Reactome: R-HSA-8866654;MetaCyc: PWY-7511;Reactome: R-HSA-110314 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination";"Recognition of DNA damage by PCNA-containing replication complex" JAMg_model_18865.3 6 Reactome: R-HSA-977347;KEGG: 00750+2.6.1.52;KEGG: 00260+2.6.1.52;KEGG: 00680+2.6.1.52;KEGG: 00270+2.6.1.52;MetaCyc: PWY-8010 "Serine biosynthesis";"Vitamin B6 metabolism";"Glycine, serine and threonine metabolism";"Methane metabolism";"Cysteine and methionine metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)" JAMg_model_20941.2 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" JAMg_model_3303.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" JAMg_model_15154.5 1 KEGG: 00051+4.2.1.68 "Fructose and mannose metabolism" JAMg_model_14654.3 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_12827.3 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" JAMg_model_18227.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_9138.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" JAMg_model_1216.3 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_3090.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" JAMg_model_19084.2 5 Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" JAMg_model_18220.1 17 Reactome: R-HSA-75955;Reactome: R-HSA-167246;KEGG: 04660+3.1.3.16;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-167152;KEGG: 04658+3.1.3.16;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;KEGG: 05235+3.1.3.16;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167242 "RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"T cell receptor signaling pathway";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Th1 and Th2 cell differentiation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat" JAMg_model_15784.3 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" JAMg_model_5303.6 4 KEGG: 00510+2.7.1.108;MetaCyc: PWY-6129;Reactome: R-HSA-4755583;Reactome: R-HSA-446199 "N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Defective DOLK causes DOLK-CDG (CDG-1m)";"Synthesis of Dolichyl-phosphate" JAMg_model_21167.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" JAMg_model_7723.1 3 Reactome: R-HSA-420029;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" JAMg_model_16243.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" JAMg_model_5870.2 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_19531.2 9 MetaCyc: PWY-5757;MetaCyc: PWY-6682;MetaCyc: PWY-7510;KEGG: 00440+4.1.1.82;MetaCyc: PWY-6322;MetaCyc: PWY-6839;KEGG: 00998+4.1.1.82;MetaCyc: PWY-7769;MetaCyc: PWY-8067 "Fosfomycin biosynthesis";"Dehydrophos biosynthesis";"Rhizocticin A and B biosynthesis";"Phosphonate and phosphinate metabolism";"Phosphinothricin tripeptide biosynthesis";"2-aminoethylphosphonate biosynthesis";"Biosynthesis of various secondary metabolites - part 2";"Phosalacine biosynthesis";"Methylphosphonate biosynthesis" JAMg_model_13489.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" JAMg_model_12635.1 3 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843 "Pentose phosphate pathway";"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis" JAMg_model_14777.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" JAMg_model_8783.3 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" JAMg_model_6657.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Intra-Golgi traffic" JAMg_model_10489.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_20180.1 8 KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-418889;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"mTOR signaling pathway";"Caspase activation via Dependence Receptors in the absence of ligand";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" JAMg_model_10003.3 9 MetaCyc: PWY-8052;MetaCyc: PWY-6351;Reactome: R-HSA-416476;Reactome: R-HSA-112043;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11 "2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events";"PLC beta mediated events";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism" JAMg_model_9084.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" JAMg_model_15548.1 13 MetaCyc: PWY-7533;MetaCyc: PWY-4061;MetaCyc: PWY-2261;KEGG: 00983+2.5.1.18;KEGG: 00053+1.8.5.1;MetaCyc: PWY-7112;MetaCyc: PWY-6842;Reactome: R-HSA-156590;MetaCyc: PWY-6370;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18;Reactome: R-HSA-196836;KEGG: 00480+2.5.1.18+1.8.5.1 "Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"Ascorbate glutathione cycle";"Drug metabolism - other enzymes";"Ascorbate and aldarate metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Glutathione conjugation";"Ascorbate recycling (cytosolic)";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Vitamin C (ascorbate) metabolism";"Glutathione metabolism" JAMg_model_8298.3 4 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-1912420 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi" JAMg_model_1960.2 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" JAMg_model_10201.4 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_19621.1 7 MetaCyc: PWY-7118;KEGG: 00630+2.3.3.9;MetaCyc: PWY-7854;MetaCyc: PWY-7295;MetaCyc: PWY-7294;KEGG: 00620+2.3.3.9;MetaCyc: PWY-6969 "Chitin degradation to ethanol";"Glyoxylate and dicarboxylate metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"L-arabinose degradation IV";"D-xylose degradation IV";"Pyruvate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" JAMg_model_6075.3 24 Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434 "Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"Mitotic Prometaphase";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"Aggrephagy";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_6498.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" JAMg_model_4720.2 3 Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110357 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1" JAMg_model_3670.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" JAMg_model_15981.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-5250924 "RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression" JAMg_model_6042.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" JAMg_model_8992.4 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_17459.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" JAMg_model_7656.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" JAMg_model_907.15 8 Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-432720;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"Lysosome Vesicle Biogenesis";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" JAMg_model_1812.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" JAMg_model_11773.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" JAMg_model_2273.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" JAMg_model_7587.3 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" JAMg_model_9881.1 5 MetaCyc: PWY-5189;Reactome: R-HSA-189451;MetaCyc: PWY-7536;KEGG: 00260+2.3.1.37;KEGG: 00860+2.3.1.37 "Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Glycine, serine and threonine metabolism";"Porphyrin and chlorophyll metabolism" JAMg_model_8478.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" JAMg_model_4840.2 10 Reactome: R-HSA-3899300;Reactome: R-HSA-8936459;Reactome: R-HSA-9615017;Reactome: R-HSA-400206;Reactome: R-HSA-9022692;Reactome: R-HSA-427413;Reactome: R-HSA-9022538;Reactome: R-HSA-9022699;Reactome: R-HSA-9022702;Reactome: R-HSA-983231 "SUMOylation of transcription cofactors";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of lipid metabolism by PPARalpha";"Regulation of MECP2 expression and activity";"NoRC negatively regulates rRNA expression";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates neuronal receptors and channels";"MECP2 regulates transcription of neuronal ligands";"Factors involved in megakaryocyte development and platelet production" JAMg_model_10398.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" JAMg_model_9184.5 6 MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism" JAMg_model_10024.5 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_10003.4 9 KEGG: 04070+3.1.4.11;Reactome: R-HSA-112043;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6351;MetaCyc: PWY-8052;Reactome: R-HSA-416476 "Phosphatidylinositol signaling system";"PLC beta mediated events";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events" JAMg_model_3009.4 1 Reactome: R-HSA-6799198 "Complex I biogenesis" JAMg_model_4998.4 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" JAMg_model_21161.2 7 Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518 "Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2" JAMg_model_8159.2 12 MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00680+4.1.2.13;KEGG: 00710+4.1.2.13;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00051+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00030+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-6142;MetaCyc: PWY-1861 "Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Pentose phosphate pathway";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" JAMg_model_12635.4 3 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843 "Pentose phosphate pathway";"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis" JAMg_model_4539.2 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" JAMg_model_5943.1 3 MetaCyc: PWY-7807;MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1 "Glyphosate degradation III";"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation" JAMg_model_14065.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" JAMg_model_2077.1 33 Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-68877;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-5663220;Reactome: R-HSA-4085377;Reactome: R-HSA-141444;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-4551638;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-3301854 "Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Mitotic Prometaphase";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"snRNP Assembly";"SUMOylation of RNA binding proteins";"RHO GTPases Activate Formins";"SUMOylation of SUMOylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"SUMOylation of chromatin organization proteins";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly" JAMg_model_18048.6 5 MetaCyc: PWY-5514;Reactome: R-HSA-70171;MetaCyc: PWY-6906;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6 "UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis";"Chitin derivatives degradation";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism" JAMg_model_7638.6 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" JAMg_model_9947.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_5828.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706 "Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit" JAMg_model_3009.3 1 Reactome: R-HSA-6799198 "Complex I biogenesis" JAMg_model_15154.3 1 KEGG: 00051+4.2.1.68 "Fructose and mannose metabolism" JAMg_model_4469.2 33 Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-4085377;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-4551638;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-159227 "Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"SUMOylation of SUMOylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of chromatin organization proteins";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA" JAMg_model_3305.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1660662 "Neutrophil degranulation";"Glycosphingolipid metabolism" JAMg_model_12148.2 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" JAMg_model_12928.3 14 KEGG: 00720+1.3.5.1;MetaCyc: PWY-6728;MetaCyc: PWY-561;MetaCyc: PWY-4302;MetaCyc: PWY-5690;KEGG: 00020+1.3.5.1;MetaCyc: PWY-3781;Reactome: R-HSA-611105;Reactome: R-HSA-71403;KEGG: 00190+1.3.5.1;MetaCyc: PWY-7279;MetaCyc: PWY-7254;KEGG: 00650+1.3.5.1;MetaCyc: PWY-6969 "Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Aerobic respiration I (cytochrome c)";"Respiratory electron transport";"Citric acid cycle (TCA cycle)";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle VII (acetate-producers)";"Butanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" JAMg_model_11757.5 6 Reactome: R-HSA-8874211;Reactome: R-HSA-8957275;Reactome: R-HSA-1655829;Reactome: R-HSA-8963889;Reactome: R-HSA-381426;Reactome: R-HSA-381033 "CREB3 factors activate genes";"Post-translational protein phosphorylation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Assembly of active LPL and LIPC lipase complexes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"ATF6 (ATF6-alpha) activates chaperones" JAMg_model_5555.1 7 Reactome: R-HSA-1660499;MetaCyc: PWY-6351;KEGG: 00562+2.7.1.67;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514;KEGG: 04070+2.7.1.67;MetaCyc: PWY-6352 "Synthesis of PIPs at the plasma membrane";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Phosphatidylinositol signaling system";"3-phosphoinositide biosynthesis" JAMg_model_11912.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_12780.2 2 Reactome: R-HSA-3214815;Reactome: R-HSA-427413 "HDACs deacetylate histones";"NoRC negatively regulates rRNA expression" JAMg_model_5118.1 4 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" JAMg_model_4646.1 2 Reactome: R-HSA-181429;Reactome: R-HSA-212676 "Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" JAMg_model_5782.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling" JAMg_model_17781.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" JAMg_model_8210.6 6 Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation" JAMg_model_8095.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_15541.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis" JAMg_model_17281.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_9277.2 3 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import" JAMg_model_16715.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Peptide chain elongation" JAMg_model_5088.5 16 MetaCyc: PWY-2221;MetaCyc: PWY-7124;MetaCyc: PWY-7218;MetaCyc: PWY-1042;MetaCyc: PWY-6901;KEGG: 00010+4.2.1.11;MetaCyc: PWY-6142;MetaCyc: PWY-5723;Reactome: R-HSA-70263;MetaCyc: PWY-6886;MetaCyc: PWY-8004;MetaCyc: PWY-1622;MetaCyc: PWY-5484;KEGG: 00680+4.2.1.11;MetaCyc: PWY-7003;Reactome: R-HSA-70171 "Entner-Doudoroff pathway III (semi-phosphorylative)";"Ethylene biosynthesis V (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Rubisco shunt";"Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycerol degradation to butanol";"Glycolysis" JAMg_model_16961.1 3 Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-6807505 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes" JAMg_model_15517.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" JAMg_model_1200.1 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_5361.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_10211.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" JAMg_model_16428.4 4 MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32;KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051 "Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I" JAMg_model_3523.3 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" JAMg_model_479.2 11 Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-5610787 "PKA activation in glucagon signalling";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"PKA activation";"Hedgehog 'off' state" JAMg_model_17659.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation" JAMg_model_19417.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" JAMg_model_4961.1 5 Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856825 "Negative regulation of MET activity";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis" JAMg_model_2795.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" JAMg_model_15784.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" JAMg_model_10886.2 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" JAMg_model_907.3 8 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-432720;Reactome: R-HSA-190873;Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"Lysosome Vesicle Biogenesis";"Gap junction degradation";"WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells" JAMg_model_6612.4 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" JAMg_model_14654.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_7200.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_3667.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_1909.6 1 Reactome: R-HSA-8949664 "Processing of SMDT1" JAMg_model_13747.1 29 Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-5696400;Reactome: R-HSA-167160;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-5696395;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-75953;Reactome: R-HSA-112382 "RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Dual Incision in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"Formation of Incision Complex in GG-NER";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex" JAMg_model_7197.2 2 KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23 "Pyrimidine metabolism";"Drug metabolism - other enzymes" JAMg_model_9889.2 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" JAMg_model_5588.2 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" JAMg_model_361.5 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" JAMg_model_8379.1 5 KEGG: 00983+2.4.2.3;MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73621;Reactome: R-HSA-73614 "Drug metabolism - other enzymes";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism";"Pyrimidine catabolism";"Pyrimidine salvage" JAMg_model_8794.1 6 MetaCyc: PWY-5530;KEGG: 00053+3.1.1.17;KEGG: 00930+3.1.1.17;KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-2221 "Sorbitol biosynthesis II";"Ascorbate and aldarate metabolism";"Caprolactam degradation";"Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)" JAMg_model_9697.1 7 Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-69205 "Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription" JAMg_model_11904.5 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" JAMg_model_19141.5 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" JAMg_model_19031.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_12221.3 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" JAMg_model_20738.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_13746.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" JAMg_model_3908.1 22 Reactome: R-HSA-5673000;Reactome: R-HSA-196299;Reactome: R-HSA-389513;Reactome: R-HSA-5467340;Reactome: R-HSA-5339716;Reactome: R-HSA-432142;Reactome: R-HSA-6811558;Reactome: R-HSA-195253;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747;Reactome: R-HSA-2467813;Reactome: R-HSA-4641262;Reactome: R-HSA-5358752;Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-5675221;Reactome: R-HSA-5467337 "RAF activation";"Beta-catenin phosphorylation cascade";"CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Platelet sensitization by LDL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Degradation of beta-catenin by the destruction complex";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"T41 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"APC truncation mutants have impaired AXIN binding" JAMg_model_7374.3 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" JAMg_model_12345.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_18902.3 3 Reactome: R-HSA-156590;KEGG: 00680+3.1.2.12;MetaCyc: PWY-1801 "Glutathione conjugation";"Methane metabolism";"Formaldehyde oxidation II (glutathione-dependent)" JAMg_model_14046.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" JAMg_model_8481.2 2 Reactome: R-HSA-203927;Reactome: R-HSA-8986944 "MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2" JAMg_model_17505.1 18 Reactome: R-HSA-1482922;Reactome: R-HSA-1482925;MetaCyc: PWY-7416;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482801;MetaCyc: PWY-6803;Reactome: R-HSA-1483166;Reactome: R-HSA-1482839;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053 "Acyl chain remodelling of PI";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PS";"Phosphatidylcholine acyl editing";"Synthesis of PA";"Acyl chain remodelling of PE";"Ether lipid metabolism";"Plasmalogen degradation";"Linoleic acid metabolism";"Anandamide biosynthesis II" JAMg_model_2602.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" JAMg_model_19123.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-901032 "Protein ubiquitination";"ER Quality Control Compartment (ERQC)" JAMg_model_9043.1 9 Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"RORA activates gene expression";"Circadian Clock";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression" JAMg_model_12039.1 7 Reactome: R-HSA-5693554;Reactome: R-HSA-426117;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Cation-coupled Chloride cotransporters";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)" JAMg_model_18195.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_19133.7 13 KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5538;MetaCyc: PWY-6728;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5913;MetaCyc: PWY-6969;Reactome: R-HSA-71403;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5537 "C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate VI";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V" JAMg_model_2683.1 2 KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753 "Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism" JAMg_model_8701.2 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" JAMg_model_5074.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" JAMg_model_17322.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" JAMg_model_9851.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_11907.3 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" JAMg_model_5284.3 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" JAMg_model_20738.7 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_2059.3 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" JAMg_model_11867.1 5 Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-3232118;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565 "G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"SUMOylation of transcription factors";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" JAMg_model_12772.5 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" JAMg_model_12928.2 14 KEGG: 00020+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-4302;MetaCyc: PWY-5690;MetaCyc: PWY-561;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6728;MetaCyc: PWY-6969;KEGG: 00650+1.3.5.1;MetaCyc: PWY-7254;KEGG: 00190+1.3.5.1;MetaCyc: PWY-7279;Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citrate cycle (TCA cycle)";"Aerobic respiration I (cytochrome c)";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Butanoate metabolism";"TCA cycle VII (acetate-producers)";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Citric acid cycle (TCA cycle)";"Respiratory electron transport" JAMg_model_10017.4 1 Reactome: R-HSA-8874211 "CREB3 factors activate genes" JAMg_model_17404.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_10024.3 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_12329.4 14 KEGG: 00190+1.3.5.1;MetaCyc: PWY-7279;Reactome: R-HSA-611105;Reactome: R-HSA-71403;MetaCyc: PWY-6969;KEGG: 00650+1.3.5.1;MetaCyc: PWY-7254;MetaCyc: PWY-561;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6728;MetaCyc: PWY-3781;KEGG: 00020+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-5690 "Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Respiratory electron transport";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Butanoate metabolism";"TCA cycle VII (acetate-producers)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Aerobic respiration I (cytochrome c)";"Citrate cycle (TCA cycle)";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle II (plants and fungi)" JAMg_model_10410.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554 "Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" JAMg_model_9298.1 6 KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660499;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1855183;Reactome: R-HSA-1660516 "Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the early endosome membrane" JAMg_model_17219.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-6798695;Reactome: R-HSA-432722;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Neutrophil degranulation";"Golgi Associated Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis" JAMg_model_7430.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" JAMg_model_11623.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" JAMg_model_5232.4 1 Reactome: R-HSA-5620924 "Intraflagellar transport" JAMg_model_3669.2 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" JAMg_model_4834.2 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" JAMg_model_12660.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_7899.1 1 Reactome: R-HSA-425366 "Transport of bile salts and organic acids, metal ions and amine compounds" JAMg_model_5862.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" JAMg_model_1324.2 7 Reactome: R-HSA-2029485;MetaCyc: PWY-7039;KEGG: 00565+3.1.4.4;MetaCyc: PWY-3561;KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Role of phospholipids in phagocytosis";"Phosphatidate metabolism, as a signaling molecule";"Ether lipid metabolism";"Choline biosynthesis III";"Glycerophospholipid metabolism";"Synthesis of PG";"Synthesis of PA" JAMg_model_8659.1 3 Reactome: R-HSA-2129379;Reactome: R-HSA-1566948;Reactome: R-HSA-1474228 "Molecules associated with elastic fibres";"Elastic fibre formation";"Degradation of the extracellular matrix" JAMg_model_14505.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" JAMg_model_16408.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" JAMg_model_5326.1 2 Reactome: R-HSA-6811436;Reactome: R-HSA-8876198 "COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs" JAMg_model_8162.2 7 Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320 "AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes" JAMg_model_2446.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-73762 "HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation" JAMg_model_479.4 11 Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1 "PKA activation";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Purine metabolism" JAMg_model_9200.2 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" JAMg_model_6323.1 4 MetaCyc: PWY-8072;MetaCyc: PWY-8040;MetaCyc: PWY-7383;KEGG: 00473+5.1.1.1 "Alanine racemization";"Ansatrienin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"D-Alanine metabolism" JAMg_model_16490.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" JAMg_model_10492.2 1 Reactome: R-HSA-110357 "Displacement of DNA glycosylase by APEX1" JAMg_model_16858.2 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" JAMg_model_3237.2 13 Reactome: R-HSA-8856825;Reactome: R-HSA-437239;Reactome: R-HSA-8856828;Reactome: R-HSA-8866427;Reactome: R-HSA-416993;Reactome: R-HSA-2132295;Reactome: R-HSA-167590;Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-177504;Reactome: R-HSA-8964038;Reactome: R-HSA-3928665;Reactome: R-HSA-182218 "Cargo recognition for clathrin-mediated endocytosis";"Recycling pathway of L1";"Clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"Trafficking of GluR2-containing AMPA receptors";"MHC class II antigen presentation";"Nef Mediated CD4 Down-regulation";"WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Retrograde neurotrophin signalling";"LDL clearance";"EPH-ephrin mediated repulsion of cells";"Nef Mediated CD8 Down-regulation" JAMg_model_6016.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" JAMg_model_12163.1 3 Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65;MetaCyc: PWY-5669 "Synthesis of PE";"Glycerophospholipid metabolism";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I" JAMg_model_19013.3 7 Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232 "Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants" JAMg_model_15492.3 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" JAMg_model_1536.2 9 Reactome: R-HSA-166208;Reactome: R-HSA-6798695;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-5674135;Reactome: R-HSA-5628897 "mTORC1-mediated signalling";"Neutrophil degranulation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"MAP2K and MAPK activation";"TP53 Regulates Metabolic Genes" JAMg_model_7597.4 8 Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68689 "Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex" JAMg_model_985.3 3 Reactome: R-HSA-3299685;Reactome: R-HSA-5628897;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"TP53 Regulates Metabolic Genes";"Glutathione metabolism" JAMg_model_17206.1 5 Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;Reactome: R-HSA-6798695;Reactome: R-HSA-164843;Reactome: R-HSA-3270619 "Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation";"2-LTR circle formation";"IRF3-mediated induction of type I IFN" JAMg_model_7496.1 4 Reactome: R-HSA-2586552;Reactome: R-HSA-983231;Reactome: R-HSA-982772;Reactome: R-HSA-1170546 "Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production";"Growth hormone receptor signaling";"Prolactin receptor signaling" JAMg_model_20738.4 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_11685.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" JAMg_model_15675.1 12 MetaCyc: PWY-6527;Reactome: R-HSA-173599;MetaCyc: PWY-3801;MetaCyc: PWY-7343;KEGG: 00500+2.7.7.9;KEGG: 00052+2.7.7.9;KEGG: 00520+2.7.7.9;KEGG: 00561+2.7.7.9;Reactome: R-HSA-3322077;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-7238 "Stachyose degradation";"Formation of the active cofactor, UDP-glucuronate";"Sucrose degradation II (sucrose synthase)";"UDP-alpha-D-glucose biosynthesis I";"Starch and sucrose metabolism";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycerolipid metabolism";"Glycogen synthesis";"Pentose and glucuronate interconversions";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose biosynthesis II" JAMg_model_12958.1 3 Reactome: R-HSA-9609690;Reactome: R-HSA-3899300;Reactome: R-HSA-6804757 "HCMV Early Events";"SUMOylation of transcription cofactors";"Regulation of TP53 Degradation" JAMg_model_2864.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_5681.1 1 Reactome: R-HSA-3295583 "TRP channels" JAMg_model_19882.1 11 Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-174437;Reactome: R-HSA-5693568;Reactome: R-HSA-69166;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942 "HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate from the C-strand";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Removal of the Flap Intermediate";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)" JAMg_model_12664.3 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" JAMg_model_16520.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" JAMg_model_10797.9 1 Reactome: R-HSA-5676934 "Protein repair" JAMg_model_9900.4 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" JAMg_model_10328.9 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" JAMg_model_20438.2 4 Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813 "Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids" JAMg_model_14120.5 11 Reactome: R-HSA-450302;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 05163+2.7.11.1;Reactome: R-HSA-171007 "activated TAK1 mediates p38 MAPK activation";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"VEGFA-VEGFR2 Pathway";"Human immunodeficiency virus 1 infection";"Oxidative Stress Induced Senescence";"Human cytomegalovirus infection";"p38MAPK events" JAMg_model_11502.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" JAMg_model_8701.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" JAMg_model_2133.1 2 Reactome: R-HSA-456926;Reactome: R-HSA-416482 "Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events" JAMg_model_4447.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" JAMg_model_17911.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_15536.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" JAMg_model_3538.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" JAMg_model_2924.1 18 MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-6803;Reactome: R-HSA-1482801;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1483166;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-7416;Reactome: R-HSA-1482922;MetaCyc: PWY-7417 "Plasmalogen degradation";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PS";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Acyl chain remodelling of PE";"Synthesis of PA";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)" JAMg_model_17671.4 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" JAMg_model_6552.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" JAMg_model_20252.2 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" JAMg_model_18780.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" JAMg_model_1147.5 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" JAMg_model_3810.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" JAMg_model_10409.3 3 Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" JAMg_model_12808.1 2 KEGG: 00563+3.5.1.89;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" JAMg_model_11402.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" JAMg_model_10808.2 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_5067.5 1 Reactome: R-HSA-8949613 "Cristae formation" JAMg_model_7190.5 12 KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-416476;Reactome: R-HSA-194840;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-418885;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416482 "PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"NRAGE signals death through JNK";"G alpha (q) signalling events";"Rho GTPase cycle";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"DCC mediated attractive signaling";"Human immunodeficiency virus 1 infection";"G alpha (12/13) signalling events" JAMg_model_1852.2 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" JAMg_model_16067.1 2 Reactome: R-HSA-162588;Reactome: R-HSA-917729 "Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)" JAMg_model_19131.7 14 MetaCyc: PWY-8052;MetaCyc: PWY-6453;MetaCyc: PWY-8055;KEGG: 00564+3.1.3.4;Reactome: R-HSA-1483213;KEGG: 00561+3.1.3.4;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8051;Reactome: R-HSA-4419969;Reactome: R-HSA-75109;Reactome: R-HSA-1483191;MetaCyc: PWY-7782;MetaCyc: PWY-8053;KEGG: 00600+3.1.3.4 "2-arachidonoylglycerol biosynthesis";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PE";"Glycerolipid metabolism";"Ether lipid metabolism";"Anandamide biosynthesis I";"Depolymerisation of the Nuclear Lamina";"Triglyceride biosynthesis";"Synthesis of PC";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Sphingolipid metabolism" JAMg_model_10062.2 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" JAMg_model_7643.2 16 Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Peptide chain elongation" JAMg_model_7586.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_8472.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" JAMg_model_5870.4 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_1006.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_17580.3 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" JAMg_model_4909.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" JAMg_model_1102.1 2 KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859 "Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade" JAMg_model_16527.1 11 KEGG: 00910+6.3.1.2;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6549;MetaCyc: PWY-6964;Reactome: R-HSA-210455;KEGG: 00220+6.3.1.2;Reactome: R-HSA-8964539;KEGG: 00630+6.3.1.2;MetaCyc: PWY-5675;MetaCyc: PWY-381;MetaCyc: PWY-6963 "Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"L-glutamine biosynthesis III";"Ammonia assimilation cycle II";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Arginine biosynthesis";"Glutamate and glutamine metabolism";"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction V (assimilatory)";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle I" JAMg_model_1970.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_20866.3 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_12129.4 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" JAMg_model_22.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" JAMg_model_11645.3 5 Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling" JAMg_model_14299.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_20389.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" JAMg_model_17419.1 12 Reactome: R-HSA-8854518;Reactome: R-HSA-6807878;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-380284;Reactome: R-HSA-381038;Reactome: R-HSA-380270 "AURKA Activation by TPX2";"COPI-mediated anterograde transport";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of proteins required for interphase microtubule organization from the centrosome";"XBP1(S) activates chaperone genes";"Recruitment of mitotic centrosome proteins and complexes" JAMg_model_19082.1 2 Reactome: R-HSA-456926;Reactome: R-HSA-416482 "Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events" JAMg_model_4471.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_6994.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_7655.4 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" JAMg_model_11740.2 9 Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-6784531;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-113501 "Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"tRNA processing in the nucleus";"DNA replication initiation";"Removal of the Flap Intermediate";"Polymerase switching";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1" JAMg_model_12320.1 18 MetaCyc: PWY-7184;MetaCyc: PWY-7197;KEGG: 00983+2.7.4.6;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7220;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7224;MetaCyc: PWY-7222;MetaCyc: PWY-7176;MetaCyc: PWY-7227;MetaCyc: PWY-7187;MetaCyc: PWY-7221;MetaCyc: PWY-6545;Reactome: R-HSA-499943;MetaCyc: PWY-7205 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Drug metabolism - other enzymes";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"CMP phosphorylation" JAMg_model_4336.1 34 Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-9639288;Reactome: R-HSA-159236;Reactome: R-HSA-141444;Reactome: R-HSA-4085377;Reactome: R-HSA-5663220;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-168276 "SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Amino acids regulate mTORC1";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of SUMOylation proteins";"RHO GTPases Activate Formins";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways" JAMg_model_17420.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" JAMg_model_16400.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" JAMg_model_3944.1 2 Reactome: R-HSA-1299308;Reactome: R-HSA-5576886 "Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)";"Phase 4 - resting membrane potential" JAMg_model_1681.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" JAMg_model_9656.1 33 Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-159236;Reactome: R-HSA-141444;Reactome: R-HSA-4085377;Reactome: R-HSA-5663220;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-68877;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-180746 "SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"ISG15 antiviral mechanism";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of SUMOylation proteins";"RHO GTPases Activate Formins";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Mitotic Prometaphase";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein" JAMg_model_16666.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" JAMg_model_20813.3 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" JAMg_model_7144.3 1 Reactome: R-HSA-71262 "Carnitine synthesis" JAMg_model_5598.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" JAMg_model_11039.1 1 Reactome: R-HSA-114608 "Platelet degranulation" JAMg_model_19704.2 2 MetaCyc: PWY-6558;Reactome: R-HSA-2022928 "Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis" JAMg_model_8686.1 2 MetaCyc: PWY-7802;MetaCyc: PWY-7799 "N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)" JAMg_model_14040.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" JAMg_model_6073.2 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" JAMg_model_997.7 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" JAMg_model_6697.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" JAMg_model_9277.1 3 Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654 "Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins" JAMg_model_15126.2 13 Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis" JAMg_model_2460.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" JAMg_model_4993.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" JAMg_model_12664.4 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" JAMg_model_15837.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" JAMg_model_949.1 5 Reactome: R-HSA-3108214;Reactome: R-HSA-5221030;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329 "SUMOylation of DNA damage response and repair proteins";"TET1,2,3 and TDG demethylate DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine" JAMg_model_8547.2 5 Reactome: R-HSA-430039;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994 "mRNA decay by 5' to 3' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" JAMg_model_11853.1 4 Reactome: R-HSA-9615710;Reactome: R-HSA-9613829;Reactome: R-HSA-3899300;Reactome: R-HSA-9646399 "Late endosomal microautophagy";"Chaperone Mediated Autophagy";"SUMOylation of transcription cofactors";"Aggrephagy" JAMg_model_18705.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" JAMg_model_4164.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" JAMg_model_4872.1 11 KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-163680;Reactome: R-HSA-380972;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9614657;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"mTOR signaling pathway";"AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"Relaxin signaling pathway";"FOXO-mediated transcription of cell death genes";"Thermogenesis";"Human papillomavirus infection";"Regulation of TP53 Activity through Phosphorylation";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" JAMg_model_8153.2 3 KEGG: 00260+3.1.3.3;KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347 "Glycine, serine and threonine metabolism";"Methane metabolism";"Serine biosynthesis" JAMg_model_10497.2 9 Reactome: R-HSA-446353;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-446343;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1 "Cell-extracellular matrix interactions";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Localization of the PINCH-ILK-PARVIN complex to focal adhesions";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway" JAMg_model_16985.1 8 Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922 "Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)" JAMg_model_20059.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_4485.3 4 MetaCyc: PWY-7437;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603 "Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"Other types of O-glycan biosynthesis";"UCH proteinases" JAMg_model_14791.1 3 Reactome: R-HSA-430039;Reactome: R-HSA-450385;Reactome: R-HSA-450513 "mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" JAMg_model_16071.1 9 Reactome: R-HSA-114608;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948 "Platelet degranulation";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants" JAMg_model_2104.2 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_8458.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_18869.1 3 Reactome: R-HSA-5368286;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9 "Mitochondrial translation initiation";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate" JAMg_model_16422.4 6 Reactome: R-HSA-114516;Reactome: R-HSA-5099900;Reactome: R-HSA-76005;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-416993 "Disinhibition of SNARE formation";"WNT5A-dependent internalization of FZD4";"Response to elevated platelet cytosolic Ca2+";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Trafficking of GluR2-containing AMPA receptors" JAMg_model_8031.1 3 KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581;MetaCyc: PWY-6823 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" JAMg_model_13521.5 8 Reactome: R-HSA-442720;Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-180024 "CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Hedgehog 'off' state";"DARPP-32 events" JAMg_model_17340.1 3 KEGG: 00030+1.1.1.44;KEGG: 00480+1.1.1.44;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Glutathione metabolism";"Pentose phosphate pathway" JAMg_model_17354.3 21 Reactome: R-HSA-937039;Reactome: R-HSA-5684264;Reactome: R-HSA-5602636;Reactome: R-HSA-445989;Reactome: R-HSA-933542;Reactome: R-HSA-5607764;Reactome: R-HSA-168638;Reactome: R-HSA-5603027;Reactome: R-HSA-1810476;Reactome: R-HSA-933543;Reactome: R-HSA-202424;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-975144;Reactome: R-HSA-5603029;Reactome: R-HSA-937041;Reactome: R-HSA-2871837;Reactome: R-HSA-5357956;Reactome: R-HSA-1169091;Reactome: R-HSA-5357905;Reactome: R-HSA-168927 "IRAK1 recruits IKK complex";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"IKBKB deficiency causes SCID";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6 mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"NOD1/2 Signaling Pathway";"IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)";"RIP-mediated NFkB activation via ZBP1";"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10";"Downstream TCR signaling";"Interleukin-1 signaling";"ER-Phagosome pathway";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IkBA variant leads to EDA-ID";"IKK complex recruitment mediated by RIP1";"FCERI mediated NF-kB activation";"TNFR1-induced NFkappaB signaling pathway";"Activation of NF-kappaB in B cells";"Regulation of TNFR1 signaling";"TICAM1, RIP1-mediated IKK complex recruitment" JAMg_model_9722.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" JAMg_model_13553.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_10388.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" JAMg_model_13295.3 5 KEGG: 05235+3.1.3.16;Reactome: R-HSA-176407;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5687128 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"MAPK6/MAPK4 signaling" JAMg_model_2074.3 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" JAMg_model_19261.1 2 Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Neutrophil degranulation";"Protein ubiquitination" JAMg_model_14134.3 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" JAMg_model_7986.1 1 Reactome: R-HSA-1483166 "Synthesis of PA" JAMg_model_463.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" JAMg_model_20950.3 2 Reactome: R-HSA-6803204;Reactome: R-HSA-1268020 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Mitochondrial protein import" JAMg_model_1904.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" JAMg_model_17485.2 4 KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3 "Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism" JAMg_model_20391.1 4 MetaCyc: PWY-7221;KEGG: 00230+6.3.5.2;KEGG: 00983+6.3.5.2;Reactome: R-HSA-73817 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis" JAMg_model_16195.1 56 Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176 "Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI2 by the proteasome";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha" JAMg_model_11321.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" JAMg_model_716.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_4397.1 7 Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-9639288 "Macroautophagy";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Amino acids regulate mTORC1" JAMg_model_2173.2 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" JAMg_model_3655.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" JAMg_model_8910.11 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" JAMg_model_10962.1 2 Reactome: R-HSA-6804756;Reactome: R-HSA-8854518 "Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2" JAMg_model_4248.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" JAMg_model_10294.1 52 Reactome: R-HSA-9018519;Reactome: R-HSA-167162;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-76061;Reactome: R-HSA-5250924;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-72203;Reactome: R-HSA-5601884;Reactome: R-HSA-76042;Reactome: R-HSA-6803529;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-6782135;Reactome: R-HSA-167242;Reactome: R-HSA-76071;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-76066;Reactome: R-HSA-167200;Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-5617472;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-167238;Reactome: R-HSA-73863;Reactome: R-HSA-5578749;Reactome: R-HSA-72163;Reactome: R-HSA-749476;Reactome: R-HSA-167160;Reactome: R-HSA-427413;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-6781827;Reactome: R-HSA-168325;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-203927;Reactome: R-HSA-73780 "Estrogen-dependent gene expression";"RNA Polymerase II HIV Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Capped Intron-Containing Pre-mRNA";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"FGFR2 alternative splicing";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"Dual incision in TC-NER";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase I Transcription Termination";"Transcriptional regulation by small RNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Viral Messenger RNA Synthesis";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"MicroRNA (miRNA) biogenesis";"RNA Polymerase III Chain Elongation" JAMg_model_20177.1 8 KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-418889;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Caspase activation via Dependence Receptors in the absence of ligand";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" JAMg_model_11562.5 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" JAMg_model_9932.7 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_19016.2 4 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes" JAMg_model_16202.1 2 Reactome: R-HSA-392154;Reactome: R-HSA-1222556 "Nitric oxide stimulates guanylate cyclase";"ROS and RNS production in phagocytes" JAMg_model_8065.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_7887.1 1 Reactome: R-HSA-1632852 "Macroautophagy" JAMg_model_2898.1 2 Reactome: R-HSA-5661270;KEGG: 00040+2.7.1.17 "Formation of xylulose-5-phosphate";"Pentose and glucuronate interconversions" JAMg_model_5870.3 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_16302.2 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" JAMg_model_13124.1 9 Reactome: R-HSA-6804114;Reactome: R-HSA-69656;Reactome: R-HSA-69231;Reactome: R-HSA-1362300;Reactome: R-HSA-2173796;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-69205 "TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription" JAMg_model_20471.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" JAMg_model_777.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" JAMg_model_8107.2 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" JAMg_model_8515.3 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" JAMg_model_11403.1 6 Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68867 "Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex" JAMg_model_10821.1 5 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635;KEGG: 00232+1.7.3.3;MetaCyc: PWY-5691;KEGG: 00230+1.7.3.3 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)";"Caffeine metabolism";"Urate conversion to allantoin I";"Purine metabolism" JAMg_model_17166.1 5 KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3 "Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Iron uptake and transport";"Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)" JAMg_model_2280.3 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" JAMg_model_6075.1 24 Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295 "Kinesins";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"Mitotic Prometaphase";"HCMV Early Events";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"RHO GTPases Activate Formins";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation" JAMg_model_4116.2 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" JAMg_model_9330.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-5620924;Reactome: R-HSA-983189;Reactome: R-HSA-1445148 "MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Intraflagellar transport";"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" JAMg_model_2076.1 33 Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-1169408;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-168333 "Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery" JAMg_model_11801.1 13 MetaCyc: PWY-7410;MetaCyc: PWY-6383;MetaCyc: PWY-5123;MetaCyc: PWY-7141;MetaCyc: PWY-7736;MetaCyc: PWY-7659;MetaCyc: PWY-6859;MetaCyc: PWY-5122;MetaCyc: PWY-7102;MetaCyc: PWY-7709;MetaCyc: PWY-7182;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7721 "Ipsdienol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"(3S)-linalool biosynthesis";"Stellatic acid biosynthesis";"Viridicatumtoxin biosynthesis";"All-trans-farnesol biosynthesis";"Geranyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"(3R)-linalool biosynthesis";"Linalool biosynthesis I";"Terpenoid backbone biosynthesis";"Methyl phomopsenoate biosynthesis" JAMg_model_7407.2 1 Reactome: R-HSA-8963901 "Chylomicron remodeling" JAMg_model_11784.2 2 Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" JAMg_model_14241.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706 "Viral mRNA Translation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit" JAMg_model_1687.3 16 Reactome: R-HSA-179409;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-176409;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-176412;Reactome: R-HSA-69017 "APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6" JAMg_model_18986.1 2 Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7 "Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis" JAMg_model_20205.2 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" JAMg_model_6042.2 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" JAMg_model_3411.2 1 Reactome: R-HSA-977347 "Serine biosynthesis" JAMg_model_8348.2 13 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706 "Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit" JAMg_model_7011.1 1 Reactome: R-HSA-400253 "Circadian Clock" JAMg_model_4349.3 8 Reactome: R-HSA-165054;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220 "Rev-mediated nuclear export of HIV RNA";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins" JAMg_model_12039.2 7 Reactome: R-HSA-5693554;Reactome: R-HSA-426117;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Cation-coupled Chloride cotransporters";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange" JAMg_model_479.1 11 Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1 "PKA activation";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Purine metabolism" JAMg_model_20692.1 1 Reactome: R-HSA-1234174 "Cellular response to hypoxia" JAMg_model_13141.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444 "Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" JAMg_model_20101.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_6678.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_18210.3 5 KEGG: 00900+2.2.1.7;MetaCyc: PWY-6892;KEGG: 00730+2.2.1.7;MetaCyc: PWY-7560;MetaCyc: PWY-6891 "Terpenoid backbone biosynthesis";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiamine metabolism";"Methylerythritol phosphate pathway II";"Thiazole biosynthesis II (aerobic bacteria)" JAMg_model_15187.4 5 Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897 "RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes" JAMg_model_1001.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" JAMg_model_18418.2 3 Reactome: R-HSA-191859;Reactome: R-HSA-72165;Reactome: R-HSA-72163 "snRNP Assembly";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" JAMg_model_9880.1 7 Reactome: R-HSA-500753;MetaCyc: PWY-5686;KEGG: 00240+2.1.3.2;KEGG: 00240+3.5.2.3;KEGG: 00250+2.1.3.2;MetaCyc: PWY-7791;MetaCyc: PWY-7790 "Pyrimidine biosynthesis";"UMP biosynthesis I";"Pyrimidine metabolism";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis III";"UMP biosynthesis II" JAMg_model_11429.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" JAMg_model_1730.2 3 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.4;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" JAMg_model_20881.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Peptide chain elongation" JAMg_model_18228.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" JAMg_model_18568.2 2 Reactome: R-HSA-2206307;Reactome: R-HSA-2024096 "MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation" JAMg_model_16814.1 2 KEGG: 00230+3.5.3.4;MetaCyc: PWY-5697 "Purine metabolism";"Allantoin degradation to ureidoglycolate I (urea producing)" JAMg_model_13054.10 3 MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism" JAMg_model_21118.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_15830.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" JAMg_model_5317.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" JAMg_model_14645.2 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" JAMg_model_1475.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" JAMg_model_10079.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-4615885 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins" JAMg_model_12824.1 6 Reactome: R-HSA-8874081;Reactome: R-HSA-2022090;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490 "MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Collagen degradation" JAMg_model_18199.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" JAMg_model_16523.1 1 Reactome: R-HSA-5689603 "UCH proteinases" JAMg_model_2281.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_7699.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" JAMg_model_8137.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" JAMg_model_17695.1 7 Reactome: R-HSA-264870;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-6798695;Reactome: R-HSA-445095;Reactome: R-HSA-373753 "Caspase-mediated cleavage of cytoskeletal proteins";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Neutrophil degranulation";"Interaction between L1 and Ankyrins";"Nephrin family interactions" JAMg_model_17170.2 17 MetaCyc: PWY-5695;MetaCyc: PWY-6608;MetaCyc: PWY-6627;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6644;MetaCyc: PWY-7179;Reactome: R-HSA-74259;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6611;MetaCyc: PWY-7179-1;MetaCyc: PWY-4202;MetaCyc: PWY-6609;MetaCyc: PWY-6620;Reactome: R-HSA-74217;MetaCyc: PWY-5532;KEGG: 00230+2.4.2.1;Reactome: R-HSA-6798695 "Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation III";"Salinosporamide A biosynthesis";"Nicotinate and nicotinamide metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Purine deoxyribonucleosides degradation I";"Purine catabolism";"Pyrimidine metabolism";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation II";"Arsenate detoxification I (mammalian)";"Adenine and adenosine salvage III";"Guanine and guanosine salvage";"Purine salvage";"Nucleoside and nucleotide degradation (archaea)";"Purine metabolism";"Neutrophil degranulation" JAMg_model_12948.3 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" JAMg_model_1474.1 4 Reactome: R-HSA-9646399;Reactome: R-HSA-3899300;Reactome: R-HSA-9613829;Reactome: R-HSA-9615710 "Aggrephagy";"SUMOylation of transcription cofactors";"Chaperone Mediated Autophagy";"Late endosomal microautophagy" JAMg_model_16769.1 4 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-1912420 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi" JAMg_model_18028.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" JAMg_model_1147.2 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" JAMg_model_8478.2 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" JAMg_model_15955.1 11 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" JAMg_model_6002.2 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_4046.2 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" JAMg_model_17296.1 1 Reactome: R-HSA-1632852 "Macroautophagy" JAMg_model_17730.2 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" JAMg_model_7189.5 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" JAMg_model_4840.3 10 Reactome: R-HSA-983231;Reactome: R-HSA-9022699;Reactome: R-HSA-9022702;Reactome: R-HSA-427413;Reactome: R-HSA-9022538;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-9615017;Reactome: R-HSA-400206;Reactome: R-HSA-3899300 "Factors involved in megakaryocyte development and platelet production";"MECP2 regulates neuronal receptors and channels";"MECP2 regulates transcription of neuronal ligands";"NoRC negatively regulates rRNA expression";"Loss of MECP2 binding ability to 5mC-DNA";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of lipid metabolism by PPARalpha";"SUMOylation of transcription cofactors" JAMg_model_17170.1 17 MetaCyc: PWY-5695;MetaCyc: PWY-6608;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6627;Reactome: R-HSA-74259;MetaCyc: PWY-6644;MetaCyc: PWY-7179;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6611;MetaCyc: PWY-7179-1;MetaCyc: PWY-4202;MetaCyc: PWY-6609;MetaCyc: PWY-6620;MetaCyc: PWY-5532;Reactome: R-HSA-74217;KEGG: 00230+2.4.2.1;Reactome: R-HSA-6798695 "Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation III";"Nicotinate and nicotinamide metabolism";"Salinosporamide A biosynthesis";"Purine catabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Purine deoxyribonucleosides degradation I";"Pyrimidine metabolism";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation II";"Arsenate detoxification I (mammalian)";"Adenine and adenosine salvage III";"Guanine and guanosine salvage";"Nucleoside and nucleotide degradation (archaea)";"Purine salvage";"Purine metabolism";"Neutrophil degranulation" JAMg_model_1096.2 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" JAMg_model_7957.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_18195.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_340.5 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" JAMg_model_4219.2 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" JAMg_model_12979.1 18 MetaCyc: PWY-7227;MetaCyc: PWY-7176;MetaCyc: PWY-7222;MetaCyc: PWY-7224;MetaCyc: PWY-7205;MetaCyc: PWY-6545;Reactome: R-HSA-499943;MetaCyc: PWY-7187;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7197;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7184;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7198 "Adenosine deoxyribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" JAMg_model_16066.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_15420.1 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" JAMg_model_17269.1 3 MetaCyc: PWY-8106;Reactome: R-HSA-6782315;MetaCyc: PWY-6700 "Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)" JAMg_model_17826.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" JAMg_model_17353.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" JAMg_model_174.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" JAMg_model_1298.1 19 Reactome: R-HSA-3000484;Reactome: R-HSA-8856825;Reactome: R-HSA-3000471;Reactome: R-HSA-8964026;Reactome: R-HSA-8856828;Reactome: R-HSA-3000480;Reactome: R-HSA-8957275;Reactome: R-HSA-202733;Reactome: R-HSA-8964038;Reactome: R-HSA-5686938;Reactome: R-HSA-975634;Reactome: R-HSA-432142;Reactome: R-HSA-381426;Reactome: R-HSA-8963888;Reactome: R-HSA-8866423;Reactome: R-HSA-8964041;Reactome: R-HSA-3000497;Reactome: R-HSA-8963901;Reactome: R-HSA-8964046 "Scavenging by Class F Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class B Receptors";"Chylomicron clearance";"Clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"Post-translational protein phosphorylation";"Cell surface interactions at the vascular wall";"LDL clearance";"Regulation of TLR by endogenous ligand";"Retinoid metabolism and transport";"Platelet sensitization by LDL";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron assembly";"VLDL assembly";"LDL remodeling";"Scavenging by Class H Receptors";"Chylomicron remodeling";"VLDL clearance" JAMg_model_11069.2 1 Reactome: R-HSA-611105 "Respiratory electron transport" JAMg_model_19511.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" JAMg_model_13313.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" JAMg_model_7346.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" JAMg_model_15388.2 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" JAMg_model_418.1 14 MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-7589;MetaCyc: PWY-5981;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-6453 "Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis" JAMg_model_9164.3 4 Reactome: R-HSA-379716;Reactome: R-HSA-2408557;KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281 "Cytosolic tRNA aminoacylation";"Selenocysteine synthesis";"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" JAMg_model_3833.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" JAMg_model_14215.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_18382.2 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" JAMg_model_18669.1 10 Reactome: R-HSA-163680;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-1445148;Reactome: R-HSA-9613354;Reactome: R-HSA-200425;Reactome: R-HSA-9619483;Reactome: R-HSA-5628897 "AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Lipophagy";"Carnitine metabolism";"Activation of AMPK downstream of NMDARs";"TP53 Regulates Metabolic Genes" JAMg_model_11737.5 1 Reactome: R-HSA-400253 "Circadian Clock" JAMg_model_18080.2 6 Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689 "L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits" JAMg_model_7726.3 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_6805.1 1 Reactome: R-HSA-5635838 "Activation of SMO" JAMg_model_538.1 2 Reactome: R-HSA-1237112;Reactome: R-HSA-8950505 "Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" JAMg_model_20101.2 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_8914.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" JAMg_model_1359.6 12 Reactome: R-HSA-418885;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-416476 "DCC mediated attractive signaling";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Rho GTPase cycle";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"NRAGE signals death through JNK";"G alpha (q) signalling events" JAMg_model_13995.1 56 Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-8939902 "Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity" JAMg_model_8476.4 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" JAMg_model_10826.1 11 Reactome: R-HSA-3656253;Reactome: R-HSA-4420332;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-202733;Reactome: R-HSA-3000170;Reactome: R-HSA-975634;Reactome: R-HSA-3560783;Reactome: R-HSA-1971475;Reactome: R-HSA-2022928;Reactome: R-HSA-2024096 "Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"Cell surface interactions at the vascular wall";"Syndecan interactions";"Retinoid metabolism and transport";"Defective B4GALT7 causes EDS, progeroid type";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG biosynthesis";"HS-GAG degradation" JAMg_model_883.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" JAMg_model_5114.2 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_10889.1 8 KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1 "Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis";"Starch and sucrose metabolism" JAMg_model_3046.1 26 Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-389977;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-389960;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-9648025;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436 "RHO GTPases Activate Formins";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"Post-chaperonin tubulin folding pathway";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"Kinesins";"Formation of tubulin folding intermediates by CCT/TriC";"Mitotic Prometaphase";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic" JAMg_model_2455.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-1663150 "Glycosphingolipid metabolism";"The activation of arylsulfatases" JAMg_model_9906.1 2 Reactome: R-HSA-444821;Reactome: R-HSA-418555 "Relaxin receptors";"G alpha (s) signalling events" JAMg_model_9947.4 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_7974.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" JAMg_model_11796.1 16 Reactome: R-HSA-8936459;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-2559580;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Oxidative Stress Induced Senescence";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX" JAMg_model_742.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" JAMg_model_6910.2 6 Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-456926 "Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)" JAMg_model_10125.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_6103.1 9 MetaCyc: PWY-5744;MetaCyc: PWY-241;MetaCyc: PWY-5789;MetaCyc: PWY-7115;Reactome: R-HSA-1475029;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-5743 "Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reversible hydration of carbon dioxide";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle" JAMg_model_4813.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" JAMg_model_1208.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_13105.1 1 Reactome: R-HSA-5657655 "MGMT-mediated DNA damage reversal" JAMg_model_9850.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" JAMg_model_10448.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" JAMg_model_947.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_13397.3 7 MetaCyc: PWY-7782;Reactome: R-HSA-1483191;MetaCyc: PWY-3385;Reactome: R-HSA-1483213;MetaCyc: PWY-7818;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7886 "Plasmalogen biosynthesis";"Synthesis of PC";"Choline biosynthesis I";"Synthesis of PE";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Glycerophospholipid metabolism";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis" JAMg_model_9200.5 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" JAMg_model_8766.1 7 Reactome: R-HSA-5368598;Reactome: R-HSA-201681;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-201688;Reactome: R-HSA-4086400;Reactome: R-HSA-4641258 "Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"TCF dependent signaling in response to WNT";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"WNT mediated activation of DVL";"PCP/CE pathway";"Degradation of DVL" JAMg_model_17490.1 5 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5675221;Reactome: R-HSA-112409 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Negative regulation of MAPK pathway";"RAF-independent MAPK1/3 activation" JAMg_model_5690.2 2 Reactome: R-HSA-606279;Reactome: R-HSA-6783310 "Deposition of new CENPA-containing nucleosomes at the centromere";"Fanconi Anemia Pathway" JAMg_model_18567.3 7 MetaCyc: PWY-7456;MetaCyc: PWY-5659;KEGG: 00051+5.4.2.8;MetaCyc: PWY-7586;MetaCyc: PWY-882;KEGG: 00520+5.4.2.8;Reactome: R-HSA-446205 "Beta-(1,4)-mannan degradation";"GDP-mannose biosynthesis";"Fructose and mannose metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose" JAMg_model_11526.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" JAMg_model_2764.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" JAMg_model_15348.1 3 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.14;Reactome: R-HSA-379726 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" JAMg_model_8812.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Viral mRNA Translation";"Peptide chain elongation" JAMg_model_3706.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" JAMg_model_5262.5 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" JAMg_model_5672.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" JAMg_model_12556.1 3 KEGG: 00534+5.1.3.17;MetaCyc: PWY-6558;Reactome: R-HSA-2022928 "Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis" JAMg_model_12827.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" JAMg_model_7013.1 2 Reactome: R-HSA-5578998;Reactome: R-HSA-174403 "Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling" JAMg_model_14413.1 4 MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14 "Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism" JAMg_model_7926.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" JAMg_model_12605.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" JAMg_model_20805.1 1 Reactome: R-HSA-6798163 "Choline catabolism" JAMg_model_4533.1 3 Reactome: R-HSA-189451;MetaCyc: PWY-7159;KEGG: 00860+1.3.3.3 "Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism" JAMg_model_3162.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits" JAMg_model_11403.4 6 Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-69052 "Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state" JAMg_model_14775.1 9 Reactome: R-HSA-5673001;Reactome: R-HSA-6794361;Reactome: R-HSA-3928662;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932;Reactome: R-HSA-9617324;Reactome: R-HSA-442982 "RAF/MAP kinase cascade";"Neurexins and neuroligins";"EPHB-mediated forward signaling";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Synaptic adhesion-like molecules";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor" JAMg_model_9043.2 9 Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472;Reactome: R-HSA-400253;Reactome: R-HSA-1368082 "Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Circadian Clock";"RORA activates gene expression" JAMg_model_1113.2 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" JAMg_model_15277.2 10 MetaCyc: PWY-1722;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;MetaCyc: PWY-5497;MetaCyc: PWY-3841;MetaCyc: PWY-6613;MetaCyc: PWY-7909;Reactome: R-HSA-196757;MetaCyc: PWY-5030 "Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Folate transformations I";"Purine nucleobases degradation II (anaerobic)";"Folate transformations II (plants)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"Metabolism of folate and pterines";"L-histidine degradation III" JAMg_model_8499.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" JAMg_model_8348.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706 "Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit" JAMg_model_5066.2 18 KEGG: 00220+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-7115;MetaCyc: PWY-7117;KEGG: 00960+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00710+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00401+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-7383 "Arginine biosynthesis";"Phenylalanine metabolism";"Sulfolactate degradation III";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"(R)-cysteate degradation";"Carbon fixation in photosynthetic organisms";"Arginine and proline metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"Alanine, aspartate and glutamate metabolism";"Cysteine and methionine metabolism";"Partial TCA cycle (obligate autotrophs)";"Novobiocin biosynthesis";"Coenzyme M biosynthesis II";"Anaerobic energy metabolism (invertebrates, cytosol)" JAMg_model_4998.5 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" JAMg_model_13244.1 7 Reactome: R-HSA-210500;MetaCyc: PWY-5921;Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2;Reactome: R-HSA-5628897;KEGG: 00471+3.5.1.2;KEGG: 00220+3.5.1.2 "Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"TP53 Regulates Metabolic Genes";"D-Glutamine and D-glutamate metabolism";"Arginine biosynthesis" JAMg_model_7320.1 8 KEGG: 00240+2.7.4.9;MetaCyc: PWY-7184;MetaCyc: PWY-7197;Reactome: R-HSA-499943;MetaCyc: PWY-6545;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7187 "Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II" JAMg_model_3303.5 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" JAMg_model_16553.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" JAMg_model_19874.4 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_4808.3 2 Reactome: R-HSA-8949215;Reactome: R-HSA-5689880 "Mitochondrial calcium ion transport";"Ub-specific processing proteases" JAMg_model_9424.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" JAMg_model_10014.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" JAMg_model_7598.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" JAMg_model_1791.1 3 Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328 "Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" JAMg_model_19316.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_8118.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" JAMg_model_17907.3 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" JAMg_model_8220.5 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_1147.6 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" JAMg_model_3677.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" JAMg_model_20674.2 56 Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-5687128;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-211733 "CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"UCH proteinases";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"MAPK6/MAPK4 signaling";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation" JAMg_model_11737.3 1 Reactome: R-HSA-400253 "Circadian Clock" JAMg_model_14961.1 4 MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-389661;KEGG: 00785+2.8.1.8 "Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism" JAMg_model_10448.2 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_1428.1 2 Reactome: R-HSA-5673001;Reactome: R-HSA-442982 "RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor" JAMg_model_19199.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" JAMg_model_16268.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" JAMg_model_4169.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Viral mRNA Translation" JAMg_model_20437.1 1 Reactome: R-HSA-6782861 "Synthesis of wybutosine at G37 of tRNA(Phe)" JAMg_model_16308.1 8 Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-380972 "TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"HSF1-dependent transactivation";"mTOR signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK" JAMg_model_850.2 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" JAMg_model_5993.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" JAMg_model_10033.1 5 Reactome: R-HSA-9033241;Reactome: R-HSA-9033500;KEGG: 00565+2.5.1.26;MetaCyc: PWY-7782;Reactome: R-HSA-75896 "Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins";"Ether lipid metabolism";"Plasmalogen biosynthesis";"Plasmalogen biosynthesis" JAMg_model_2273.4 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" JAMg_model_19116.5 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_13932.2 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" JAMg_model_14930.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" JAMg_model_342.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" JAMg_model_9054.5 3 MetaCyc: PWY-6117;KEGG: 00330+2.3.1.57;MetaCyc: PWY-0 "Spermine and spermidine degradation I";"Arginine and proline metabolism";"Putrescine degradation III" JAMg_model_20218.2 2 Reactome: R-HSA-5173105;Reactome: R-HSA-5083628 "O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3" JAMg_model_2777.6 14 Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression" JAMg_model_21357.3 7 Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284 "Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome" JAMg_model_907.12 8 Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-432720;Reactome: R-HSA-190873;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-5099900 "Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4" JAMg_model_7011.2 1 Reactome: R-HSA-400253 "Circadian Clock" JAMg_model_1474.3 4 Reactome: R-HSA-9646399;Reactome: R-HSA-9615710;Reactome: R-HSA-9613829;Reactome: R-HSA-3899300 "Aggrephagy";"Late endosomal microautophagy";"Chaperone Mediated Autophagy";"SUMOylation of transcription cofactors" JAMg_model_10341.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" JAMg_model_1876.3 11 Reactome: R-HSA-6785631;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-1963642;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-8863795;Reactome: R-HSA-1250196;Reactome: R-HSA-1227986;Reactome: R-HSA-8847993;Reactome: R-HSA-9664565 "ERBB2 Regulates Cell Motility";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K events in ERBB2 signaling";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"Downregulation of ERBB2 signaling";"SHC1 events in ERBB2 signaling";"Signaling by ERBB2";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2 KD Mutants" JAMg_model_18015.2 5 Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-350054;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" JAMg_model_10327.1 7 Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-1369062;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-6791226 "mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"ABC transporters in lipid homeostasis";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_2477.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" JAMg_model_460.2 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_13140.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_12452.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" JAMg_model_20692.2 1 Reactome: R-HSA-1234174 "Cellular response to hypoxia" JAMg_model_9188.1 6 KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107 "Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" JAMg_model_19503.3 40 KEGG: 00623+1.1.1.35;MetaCyc: PWY-1361;KEGG: 00640+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;MetaCyc: PWY-7779;MetaCyc: PWY-7216;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;MetaCyc: PWY-7094;MetaCyc: PWY-6863;MetaCyc: PWY-7654;MetaCyc: PWY-5136;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;MetaCyc: PWY-6435;MetaCyc: PWY-7778;KEGG: 00903+4.2.1.17;MetaCyc: PWY-6944;MetaCyc: PWY-7007;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;MetaCyc: PWY-7726;MetaCyc: PWY-7401;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;MetaCyc: PWY-7656;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00360+4.2.1.17;KEGG: 00627+4.2.1.17;KEGG: 00410+4.2.1.17;MetaCyc: PWY-5177;MetaCyc: PWY-6583;MetaCyc: PWY-5138 "Toluene degradation";"Benzoyl-coa degradation I (aerobic)";"Propanoate metabolism";"Geraniol degradation";"Caprolactam degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl tert-butyl ether degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Carbon fixation pathways in prokaryotes";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Fatty acid salvage";"Pyruvate fermentation to hexanol (engineered)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid elongation";"Butanoate metabolism";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"4-hydroxybenzoate biosynthesis III (plants)";"2-methylpropene degradation";"Limonene and pinene degradation";"Androstenedione degradation";"Methyl ketone biosynthesis (engineered)";"Benzoate degradation";"Tryptophan metabolism";"Fermentation to 2-methylbutanoate";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"Spodoptera littoralis pheromone biosynthesis";"Valine, leucine and isoleucine degradation";"Pyruvate fermentation to butanol II (engineered)";"Lysine degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Phenylalanine metabolism";"Aminobenzoate degradation";"beta-Alanine metabolism";"Glutaryl-coa degradation";"Pyruvate fermentation to butanol I";"Fatty acid beta-oxidation IV (unsaturated, even number)" JAMg_model_4541.6 7 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2" JAMg_model_492.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_19491.8 4 MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7;Reactome: R-HSA-1362409;Reactome: R-HSA-947581 "[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism";"Mitochondrial iron-sulfur cluster biogenesis";"Molybdenum cofactor biosynthesis" JAMg_model_2595.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_21130.1 6 Reactome: R-HSA-9033241;KEGG: 00380+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;KEGG: 00630+1.11.1.6;Reactome: R-HSA-6798695 "Peroxisomal protein import";"Tryptophan metabolism";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Glyoxylate and dicarboxylate metabolism";"Neutrophil degranulation" JAMg_model_9564.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_19035.2 3 MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783 "Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" JAMg_model_13894.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" JAMg_model_3750.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385 "KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" JAMg_model_17734.9 5 MetaCyc: PWY-5189;Reactome: R-HSA-189451;KEGG: 00860+4.2.1.24;MetaCyc: PWY-5188;Reactome: R-HSA-6798695 "Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Neutrophil degranulation" JAMg_model_13220.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_8436.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_7011.3 1 Reactome: R-HSA-400253 "Circadian Clock" JAMg_model_12281.7 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" JAMg_model_21047.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" JAMg_model_8466.1 3 Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691 "Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" JAMg_model_15063.1 3 Reactome: R-HSA-1660661;MetaCyc: PWY-5129;KEGG: 00600+1.14.19.17 "Sphingolipid de novo biosynthesis";"Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism" JAMg_model_15895.3 7 Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-5628897 "Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Macroautophagy";"mTOR signalling";"TP53 Regulates Metabolic Genes" JAMg_model_12121.5 6 MetaCyc: PWY-6118;Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6952;Reactome: R-HSA-163560;MetaCyc: PWY-4261 "Glycerol-3-phosphate shuttle";"Synthesis of PA";"Glycerophospholipid metabolism";"Glycerophosphodiester degradation";"Triglyceride catabolism";"Glycerol degradation I" JAMg_model_16664.1 11 KEGG: 00480+1.1.1.42;MetaCyc: PWY-7124;MetaCyc: PWY-6728;MetaCyc: PWY-7268;MetaCyc: PWY-5913;MetaCyc: PWY-6969;KEGG: 00020+1.1.1.42;KEGG: 00720+1.1.1.42;MetaCyc: PWY-7254;MetaCyc: PWY-6549;Reactome: R-HSA-71403 "Glutathione metabolism";"Ethylene biosynthesis V (engineered)";"Methylaspartate cycle";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"L-glutamine biosynthesis III";"Citric acid cycle (TCA cycle)" JAMg_model_6003.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-2672351;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"Stimuli-sensing channels";"mRNA decay by 5' to 3' exoribonuclease" JAMg_model_4403.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_1106.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_8812.2 13 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706 "Viral mRNA Translation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit" JAMg_model_17689.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" JAMg_model_5184.1 2 Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" JAMg_model_481.1 11 MetaCyc: PWY-7268;MetaCyc: PWY-6728;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7124;Reactome: R-HSA-71403;MetaCyc: PWY-6549;KEGG: 00720+1.1.1.42;MetaCyc: PWY-7254;MetaCyc: PWY-5913;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6969 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Methylaspartate cycle";"Glutathione metabolism";"Ethylene biosynthesis V (engineered)";"Citric acid cycle (TCA cycle)";"L-glutamine biosynthesis III";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" JAMg_model_10631.1 12 MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803 "Anandamide biosynthesis II";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing" JAMg_model_8041.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" JAMg_model_5689.2 2 Reactome: R-HSA-6807505;Reactome: R-HSA-191859 "RNA polymerase II transcribes snRNA genes";"snRNP Assembly" JAMg_model_6805.4 1 Reactome: R-HSA-5635838 "Activation of SMO" JAMg_model_11096.1 1 Reactome: R-HSA-376172 "DSCAM interactions" JAMg_model_11913.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" JAMg_model_14482.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" JAMg_model_10500.1 5 Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-72163 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway" JAMg_model_10800.1 8 Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-68962 "Removal of the Flap Intermediate";"Polymerase switching";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex" JAMg_model_9766.2 7 KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;MetaCyc: PWY-8052;MetaCyc: PWY-6351;MetaCyc: PWY-7039 "Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule" JAMg_model_6835.1 2 Reactome: R-HSA-6802953;Reactome: R-HSA-5658442 "RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs" JAMg_model_19672.3 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" JAMg_model_1040.5 1 Reactome: R-HSA-5620924 "Intraflagellar transport" JAMg_model_4506.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" JAMg_model_15870.2 8 Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1 "Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis / Gluconeogenesis";"Galactose metabolism" JAMg_model_9881.2 5 KEGG: 00860+2.3.1.37;KEGG: 00260+2.3.1.37;Reactome: R-HSA-189451;MetaCyc: PWY-7536;MetaCyc: PWY-5189 "Porphyrin and chlorophyll metabolism";"Glycine, serine and threonine metabolism";"Heme biosynthesis";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)" JAMg_model_15465.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" JAMg_model_19302.1 3 Reactome: R-HSA-3108214;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395 "SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER" JAMg_model_3411.6 1 Reactome: R-HSA-977347 "Serine biosynthesis" JAMg_model_11595.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" JAMg_model_11735.1 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_8464.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691 "Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" JAMg_model_3217.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_20218.1 2 Reactome: R-HSA-5083628;Reactome: R-HSA-5173105 "Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation" JAMg_model_4425.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_15512.1 3 KEGG: 00480+4.3.2.9;Reactome: R-HSA-174403;MetaCyc: PWY-4041 "Glutathione metabolism";"Glutathione synthesis and recycling";"Gamma-glutamyl cycle" JAMg_model_11150.1 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_15716.1 6 MetaCyc: PWY-7290;Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122 "Escherichia coli serotype O86 O-antigen biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis" JAMg_model_11703.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" JAMg_model_20201.1 8 Reactome: R-HSA-1268020;Reactome: R-HSA-2151201;Reactome: R-HSA-163210;KEGG: 00195+7.1.2.2;Reactome: R-HSA-8949613;KEGG: 00190+7.1.2.2;Reactome: R-HSA-5693607;MetaCyc: PWY-7980 "Mitochondrial protein import";"Transcriptional activation of mitochondrial biogenesis";"Formation of ATP by chemiosmotic coupling";"Photosynthesis";"Cristae formation";"Oxidative phosphorylation";"Processing of DNA double-strand break ends";"ATP biosynthesis" JAMg_model_9454.2 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" JAMg_model_15573.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" JAMg_model_3425.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" JAMg_model_13545.3 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" JAMg_model_13715.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_12130.2 24 Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295 "Kinesins";"Mitotic Prometaphase";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation" JAMg_model_2682.2 2 Reactome: R-HSA-190873;Reactome: R-HSA-399719 "Gap junction degradation";"Trafficking of AMPA receptors" JAMg_model_18211.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" JAMg_model_9150.1 7 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway" JAMg_model_8934.1 56 Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-5687128 "Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"FCERI mediated NF-kB activation";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling" JAMg_model_18210.1 5 MetaCyc: PWY-6892;KEGG: 00730+2.2.1.7;KEGG: 00900+2.2.1.7;MetaCyc: PWY-7560;MetaCyc: PWY-6891 "Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiamine metabolism";"Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II";"Thiazole biosynthesis II (aerobic bacteria)" JAMg_model_21059.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_15830.2 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" JAMg_model_3217.4 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_20576.4 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" JAMg_model_5740.2 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" JAMg_model_18816.1 10 KEGG: 00010+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00052+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00030+2.7.1.11;KEGG: 00051+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1861 "Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Galactose metabolism";"1,3-propanediol biosynthesis (engineered)";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Glycolysis";"Methane metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" JAMg_model_18675.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_10171.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" JAMg_model_9804.1 8 Reactome: R-HSA-5628897;Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1632852;Reactome: R-HSA-165181;Reactome: R-HSA-1445148;Reactome: R-HSA-380972;Reactome: R-HSA-8854214 "TP53 Regulates Metabolic Genes";"VxPx cargo-targeting to cilium";"Insulin processing";"Macroautophagy";"Inhibition of TSC complex formation by PKB";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Energy dependent regulation of mTOR by LKB1-AMPK";"TBC/RABGAPs" JAMg_model_18312.1 29 Reactome: R-HSA-912446;Reactome: R-HSA-3371511;Reactome: R-HSA-3108214;Reactome: R-HSA-5685938;Reactome: R-HSA-5696395;Reactome: R-HSA-3371453;Reactome: R-HSA-6804756;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-110312;Reactome: R-HSA-6783310;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-68962;Reactome: R-HSA-174437;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-176187;Reactome: R-HSA-69166 "Meiotic recombination";"HSF1 activation";"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)";"Formation of Incision Complex in GG-NER";"Regulation of HSF1-mediated heat shock response";"Regulation of TP53 Activity through Phosphorylation";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Translesion synthesis by REV1";"Fanconi Anemia Pathway";"Translesion synthesis by POLK";"Dual incision in TC-NER";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of ATR in response to replication stress";"Removal of the Flap Intermediate" JAMg_model_114.1 24 Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-983189 "MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Aggrephagy";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"Mitotic Prometaphase";"HCMV Early Events";"Kinesins" JAMg_model_10020.2 4 Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1;KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841 "Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism";"Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)" JAMg_model_12510.2 1 Reactome: R-HSA-6803207 "TP53 Regulates Transcription of Caspase Activators and Caspases" JAMg_model_3816.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" JAMg_model_5284.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" JAMg_model_20510.1 12 MetaCyc: PWY-6728;KEGG: 00660+4.1.3.25;MetaCyc: PWY-7118;MetaCyc: PWY-7294;MetaCyc: PWY-5744;MetaCyc: PWY-5749;MetaCyc: PWY-7295;MetaCyc: PWY-7854;KEGG: 00630+3.1.2.30+2.3.3.9;KEGG: 00620+2.3.3.9;KEGG: 00720+4.1.3.25;MetaCyc: PWY-6969 "Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"Chitin degradation to ethanol";"D-xylose degradation IV";"Glyoxylate assimilation";"Itaconate degradation";"L-arabinose degradation IV";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" JAMg_model_9141.5 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_1025.2 5 KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661 "Lysine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation" JAMg_model_15781.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_16621.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_17178.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" JAMg_model_18563.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation" JAMg_model_11349.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" JAMg_model_2857.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" JAMg_model_17283.3 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_15193.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_8702.7 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" JAMg_model_15970.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" JAMg_model_500.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" JAMg_model_11556.6 15 Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723 "Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation" JAMg_model_8834.4 10 MetaCyc: PWY-7511;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6804756 "Protein ubiquitination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation" JAMg_model_13715.4 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_1641.2 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" JAMg_model_17078.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" JAMg_model_15480.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" JAMg_model_16066.3 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_1173.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" JAMg_model_17588.2 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" JAMg_model_3007.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" JAMg_model_5220.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" JAMg_model_20512.1 3 Reactome: R-HSA-2672351;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20 "Stimuli-sensing channels";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" JAMg_model_16283.1 4 Reactome: R-HSA-964975;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7204;MetaCyc: PWY-7282 "Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis" JAMg_model_18103.1 17 Reactome: R-HSA-69202;Reactome: R-HSA-1912408;Reactome: R-HSA-6804114;Reactome: R-HSA-2173796;Reactome: R-HSA-111448;Reactome: R-HSA-69231;Reactome: R-HSA-2559580;Reactome: R-HSA-1538133;Reactome: R-HSA-8953750;Reactome: R-HSA-113501;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-9616222;Reactome: R-HSA-139915;Reactome: R-HSA-2559585;Reactome: R-HSA-1362300;Reactome: R-HSA-69656 "Cyclin E associated events during G1/S transition";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Activation of NOXA and translocation to mitochondria";"Cyclin D associated events in G1";"Oxidative Stress Induced Senescence";"G0 and Early G1";"Transcriptional Regulation by E2F6";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"Transcriptional regulation of granulopoiesis";"Activation of PUMA and translocation to mitochondria";"Oncogene Induced Senescence";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry" JAMg_model_20679.1 10 Reactome: R-HSA-8934903;Reactome: R-HSA-6814122;Reactome: R-HSA-201688;Reactome: R-HSA-6798695;Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-2514853;Reactome: R-HSA-8939243;Reactome: R-HSA-1483191;Reactome: R-HSA-445144 "Receptor Mediated Mitophagy";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"WNT mediated activation of DVL";"Neutrophil degranulation";"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"Condensation of Prometaphase Chromosomes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Synthesis of PC";"Signal transduction by L1" JAMg_model_6318.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" JAMg_model_16099.2 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" JAMg_model_14777.2 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" JAMg_model_17961.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" JAMg_model_5493.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" JAMg_model_5067.3 1 Reactome: R-HSA-8949613 "Cristae formation" JAMg_model_5495.2 1 Reactome: R-HSA-6799198 "Complex I biogenesis" JAMg_model_13244.3 7 Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2 "Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism" JAMg_model_8698.1 22 MetaCyc: PWY-7727;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7606;MetaCyc: PWY-6958;MetaCyc: PWY-7035;MetaCyc: PWY-7726;MetaCyc: PWY-5353;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7053;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7049;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7728;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7592;MetaCyc: PWY-7725 "Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"(9Z)-tricosene biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Fatty acid elongation";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)" JAMg_model_15949.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_8298.8 4 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-1912420 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi" JAMg_model_16711.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_15137.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_13143.2 3 KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369 "Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis" JAMg_model_3806.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" JAMg_model_1523.4 2 Reactome: R-HSA-8949613;Reactome: R-HSA-1268020 "Cristae formation";"Mitochondrial protein import" JAMg_model_18117.6 12 KEGG: 00270+4.4.1.13;MetaCyc: PWY-6842;MetaCyc: PWY-7901;MetaCyc: PWY-801;Reactome: R-HSA-71240;MetaCyc: PWY-2821;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6309;KEGG: 00380+2.6.1.7;MetaCyc: PWY-601;MetaCyc: PWY-1187;MetaCyc: PWY-6936 "Cysteine and methionine metabolism";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from tyrosine";"Homocysteine and cysteine interconversion";"Tryptophan catabolism";"Glucosinolate biosynthesis from phenylalanine";"Selenocompound metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"Glucosinolate biosynthesis from tryptophan";"Glucosinolate biosynthesis from homomethionine";"Seleno-amino acid biosynthesis (plants)" JAMg_model_2280.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" JAMg_model_10096.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_7900.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" JAMg_model_5863.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" JAMg_model_11773.2 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" JAMg_model_20615.1 5 Reactome: R-HSA-70263;KEGG: 00020+4.1.1.32;KEGG: 00620+4.1.1.32;KEGG: 00010+4.1.1.32;MetaCyc: PWY-7383 "Gluconeogenesis";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)" JAMg_model_20372.1 3 Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-6807505 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes" JAMg_model_13530.1 12 KEGG: 00052+2.7.7.9;KEGG: 00500+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-7343;MetaCyc: PWY-6527;Reactome: R-HSA-173599;MetaCyc: PWY-7817;MetaCyc: PWY-7238;Reactome: R-HSA-3322077;KEGG: 00040+2.7.7.9;KEGG: 00520+2.7.7.9;KEGG: 00561+2.7.7.9 "Galactose metabolism";"Starch and sucrose metabolism";"Sucrose degradation II (sucrose synthase)";"UDP-alpha-D-glucose biosynthesis I";"Stachyose degradation";"Formation of the active cofactor, UDP-glucuronate";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose biosynthesis II";"Glycogen synthesis";"Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"Glycerolipid metabolism" JAMg_model_1474.2 4 Reactome: R-HSA-3899300;Reactome: R-HSA-9615710;Reactome: R-HSA-9613829;Reactome: R-HSA-9646399 "SUMOylation of transcription cofactors";"Late endosomal microautophagy";"Chaperone Mediated Autophagy";"Aggrephagy" JAMg_model_1216.5 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_14726.1 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" JAMg_model_4742.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" JAMg_model_10940.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" JAMg_model_11406.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" JAMg_model_7791.3 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" JAMg_model_10909.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" JAMg_model_9798.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" JAMg_model_3663.1 5 KEGG: 00983+2.7.1.21;Reactome: R-HSA-69205;MetaCyc: PWY-7199;KEGG: 00240+2.7.1.21;Reactome: R-HSA-73614 "Drug metabolism - other enzymes";"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Pyrimidine salvage" JAMg_model_2002.3 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" JAMg_model_8940.2 5 Reactome: R-HSA-380994;Reactome: R-HSA-8963693;Reactome: R-HSA-9633012;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895 "ATF4 activates genes in response to endoplasmic reticulum stress";"Aspartate and asparagine metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency" JAMg_model_15332.1 3 KEGG: 00511+3.2.1.45;KEGG: 00600+3.2.1.45;Reactome: R-HSA-1660662 "Other glycan degradation";"Sphingolipid metabolism";"Glycosphingolipid metabolism" JAMg_model_17316.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_11648.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556 "Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes" JAMg_model_4840.1 10 Reactome: R-HSA-3899300;Reactome: R-HSA-8936459;Reactome: R-HSA-9615017;Reactome: R-HSA-400206;Reactome: R-HSA-9022692;Reactome: R-HSA-9022538;Reactome: R-HSA-427413;Reactome: R-HSA-9022699;Reactome: R-HSA-9022702;Reactome: R-HSA-983231 "SUMOylation of transcription cofactors";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of lipid metabolism by PPARalpha";"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to 5mC-DNA";"NoRC negatively regulates rRNA expression";"MECP2 regulates neuronal receptors and channels";"MECP2 regulates transcription of neuronal ligands";"Factors involved in megakaryocyte development and platelet production" JAMg_model_3713.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" JAMg_model_8481.5 2 Reactome: R-HSA-203927;Reactome: R-HSA-8986944 "MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2" JAMg_model_18681.4 1 KEGG: 00230+4.6.1.2 "Purine metabolism" JAMg_model_15514.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane" JAMg_model_2598.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" JAMg_model_19503.1 58 KEGG: 00623+1.1.1.35;MetaCyc: PWY-1361;KEGG: 00640+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17;MetaCyc: PWY-7216;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.211;KEGG: 00930+4.2.1.17;MetaCyc: PWY-7606;MetaCyc: PWY-7779;Reactome: R-HSA-77305;MetaCyc: PWY-6863;MetaCyc: PWY-6946;MetaCyc: PWY-7094;Reactome: R-HSA-77288;KEGG: 00280+4.2.1.17;MetaCyc: PWY-7654;MetaCyc: PWY-5136;Reactome: R-HSA-77310;KEGG: 00062+4.2.1.17+1.1.1.211;KEGG: 00720+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;MetaCyc: PWY-6435;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;KEGG: 00903+4.2.1.17;MetaCyc: PWY-6944;KEGG: 00650+4.2.1.17;Reactome: R-HSA-77348;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;Reactome: R-HSA-77285;Reactome: R-HSA-77350;MetaCyc: PWY-5109;KEGG: 00592+4.2.1.17;MetaCyc: PWY-7401;MetaCyc: PWY-7726;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00362+4.2.1.17;KEGG: 00360+4.2.1.17;MetaCyc: PWY-5138;MetaCyc: PWY-5177;MetaCyc: PWY-6583;Reactome: R-HSA-77346;KEGG: 00410+4.2.1.17;KEGG: 00627+4.2.1.17;Reactome: R-HSA-1482798;KEGG: 00281+4.2.1.17 "Toluene degradation";"Benzoyl-coa degradation I (aerobic)";"Propanoate metabolism";"Geraniol degradation";"Lysine degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Carbon fixation pathways in prokaryotes";"Caprolactam degradation";"Fatty acid degradation";"Caprolactam degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl tert-butyl ether degradation";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Pyruvate fermentation to hexanol (engineered)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Fatty acid salvage";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Valine, leucine and isoleucine degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Fatty acid elongation";"Carbon fixation pathways in prokaryotes";"Fatty acid elongation";"2-methylpropene degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Butanoate metabolism";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Limonene and pinene degradation";"Androstenedione degradation";"Butanoate metabolism";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Benzoate degradation";"Tryptophan metabolism";"Tryptophan metabolism";"Methyl ketone biosynthesis (engineered)";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Fermentation to 2-methylbutanoate";"alpha-Linolenic acid metabolism";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid degradation";"Spodoptera littoralis pheromone biosynthesis";"Valine, leucine and isoleucine degradation";"Pyruvate fermentation to butanol II (engineered)";"Lysine degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Benzoate degradation";"Phenylalanine metabolism";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Glutaryl-coa degradation";"Pyruvate fermentation to butanol I";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"beta-Alanine metabolism";"Aminobenzoate degradation";"Acyl chain remodeling of CL";"Geraniol degradation" JAMg_model_16528.4 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" JAMg_model_9136.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" JAMg_model_6704.1 4 Reactome: R-HSA-202433;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-2393930 "Generation of second messenger molecules";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Phosphate bond hydrolysis by NUDT proteins" JAMg_model_21121.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" JAMg_model_8557.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" JAMg_model_21355.2 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" JAMg_model_18815.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-606279;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "Resolution of Sister Chromatid Cohesion";"Deposition of new CENPA-containing nucleosomes at the centromere";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" JAMg_model_19470.1 2 Reactome: R-HSA-2151201;KEGG: 00970+6.1.1.14 "Transcriptional activation of mitochondrial biogenesis";"Aminoacyl-tRNA biosynthesis" JAMg_model_5913.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" JAMg_model_5588.7 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" JAMg_model_15621.4 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" JAMg_model_7339.1 1 Reactome: R-HSA-5617472 "Activation of anterior HOX genes in hindbrain development during early embryogenesis" JAMg_model_7934.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" JAMg_model_7521.1 2 Reactome: R-HSA-5693554;Reactome: R-HSA-2564830 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Cytosolic iron-sulfur cluster assembly" JAMg_model_19162.4 1 Reactome: R-HSA-163560 "Triglyceride catabolism" JAMg_model_11689.3 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" JAMg_model_559.2 16 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-9633012 "Peptide chain elongation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" JAMg_model_5561.2 5 Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling" JAMg_model_12392.2 1 KEGG: 00970+6.1.1.20 "Aminoacyl-tRNA biosynthesis" JAMg_model_7423.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" JAMg_model_18418.1 3 Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-72165 "snRNP Assembly";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" JAMg_model_2182.2 4 Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" JAMg_model_7844.1 6 MetaCyc: PWY-6368;KEGG: 04070+3.1.3.64+3.1.3.95;KEGG: 00562+3.1.3.64+3.1.3.95;MetaCyc: PWY-6580;MetaCyc: PWY-6367;Reactome: R-HSA-1660499 "3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)";"D-myo-inositol-5-phosphate metabolism";"Synthesis of PIPs at the plasma membrane" JAMg_model_8880.1 1 Reactome: R-HSA-211981 "Xenobiotics" JAMg_model_3507.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436 "COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic" JAMg_model_6456.2 22 KEGG: 00520+5.3.1.9;MetaCyc: PWY-7238;Reactome: R-HSA-6798695;MetaCyc: PWY-622;MetaCyc: PWY-6981;MetaCyc: PWY-5514;Reactome: R-HSA-5628897;MetaCyc: PWY-6142;MetaCyc: PWY-7347;MetaCyc: PWY-5054;KEGG: 00010+5.3.1.9;MetaCyc: PWY-621;Reactome: R-HSA-70263;MetaCyc: PWY-7385;MetaCyc: PWY-5659;KEGG: 00030+5.3.1.9;MetaCyc: PWY-3801;KEGG: 00500+5.3.1.9;MetaCyc: PWY-6992;MetaCyc: PWY-8013;MetaCyc: PWY-5384;Reactome: R-HSA-70171 "Amino sugar and nucleotide sugar metabolism";"Sucrose biosynthesis II";"Neutrophil degranulation";"Starch biosynthesis";"Chitin biosynthesis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"TP53 Regulates Metabolic Genes";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Sucrose biosynthesis III";"D-sorbitol biosynthesis I";"Glycolysis / Gluconeogenesis";"Sucrose degradation III (sucrose invertase)";"Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"GDP-mannose biosynthesis";"Pentose phosphate pathway";"Sucrose degradation II (sucrose synthase)";"Starch and sucrose metabolism";"1,5-anhydrofructose degradation";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Sucrose degradation IV (sucrose phosphorylase)";"Glycolysis" JAMg_model_20859.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Peptide chain elongation" JAMg_model_8477.4 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" JAMg_model_671.3 6 Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-6804756 "Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation" JAMg_model_8010.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_19360.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_11252.8 9 MetaCyc: PWY-5667;MetaCyc: PWY-7902;MetaCyc: PWY-6118;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.94;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7385;MetaCyc: PWY-7411;Reactome: R-HSA-1483166 "CDP-diacylglycerol biosynthesis I";"Glucosylglycerol biosynthesis";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA" JAMg_model_12780.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214815 "NoRC negatively regulates rRNA expression";"HDACs deacetylate histones" JAMg_model_12731.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" JAMg_model_14597.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers" JAMg_model_7472.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_197.3 29 Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-167162;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-73863;Reactome: R-HSA-76042;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-73772;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-5696400;Reactome: R-HSA-167160;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-6796648;Reactome: R-HSA-5696395;Reactome: R-HSA-167200;Reactome: R-HSA-75953;Reactome: R-HSA-112382 "RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II HIV Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Dual Incision in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of Incision Complex in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex" JAMg_model_12540.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_3208.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-73856 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination" JAMg_model_15927.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8875656 "RAB geranylgeranylation";"MET receptor recycling" JAMg_model_15453.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes" JAMg_model_1778.1 2 KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668 "Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" JAMg_model_21047.2 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" JAMg_model_15621.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" JAMg_model_20489.1 11 Reactome: R-HSA-5213460;Reactome: R-HSA-5357786;Reactome: R-HSA-75158;Reactome: R-HSA-2562578;Reactome: R-HSA-933543;Reactome: R-HSA-69416;Reactome: R-HSA-75157;Reactome: R-HSA-140534;Reactome: R-HSA-9013957;Reactome: R-HSA-3371378;Reactome: R-HSA-5218900 "RIPK1-mediated regulated necrosis";"TNFR1-induced proapoptotic signaling";"TRAIL signaling";"TRIF-mediated programmed cell death";"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10";"Dimerization of procaspase-8";"FasL/ CD95L signaling";"Caspase activation via Death Receptors in the presence of ligand";"TLR3-mediated TICAM1-dependent programmed cell death";"Regulation by c-FLIP";"CASP8 activity is inhibited" JAMg_model_15277.5 10 MetaCyc: PWY-5497;MetaCyc: PWY-2201;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;MetaCyc: PWY-5030;Reactome: R-HSA-196757;MetaCyc: PWY-3841;MetaCyc: PWY-7909;MetaCyc: PWY-6613 "Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"L-histidine degradation III";"Metabolism of folate and pterines";"Folate transformations II (plants)";"Formaldehyde oxidation VII (THF pathway)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate" JAMg_model_16353.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" JAMg_model_8361.2 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" JAMg_model_17419.4 12 Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-381038;Reactome: R-HSA-6807878;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436 "Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"XBP1(S) activates chaperone genes";"COPI-mediated anterograde transport";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic" JAMg_model_20929.2 6 Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257 "Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion" JAMg_model_12523.1 3 KEGG: 00270+1.13.11.54;MetaCyc: PWY-4361;Reactome: R-HSA-1237112 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway" JAMg_model_16223.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" JAMg_model_3003.1 52 Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-174154;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-5687128 "Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FCERI mediated NF-kB activation";"UCH proteinases";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Securin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"MAPK6/MAPK4 signaling" JAMg_model_8477.2 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" JAMg_model_17419.6 12 Reactome: R-HSA-381038;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-8854518;Reactome: R-HSA-6807878 "XBP1(S) activates chaperone genes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"AURKA Activation by TPX2";"COPI-mediated anterograde transport" JAMg_model_17269.2 3 MetaCyc: PWY-8106;Reactome: R-HSA-6782315;MetaCyc: PWY-6700 "Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)" JAMg_model_16517.1 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" JAMg_model_1460.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_15311.3 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_15099.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_11895.1 5 KEGG: 00860+4.1.1.37;MetaCyc: PWY-5531;Reactome: R-HSA-189451;MetaCyc: PWY-7766;MetaCyc: PWY-7159 "Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Heme biosynthesis";"Heme b biosynthesis IV (Gram-positive bacteria)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)" JAMg_model_5765.1 6 Reactome: R-HSA-5389840;Reactome: R-HSA-4085001;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;KEGG: 00540+2.7.7.38;MetaCyc: PWY-1269 "Mitochondrial translation elongation";"Sialic acid metabolism";"Mitochondrial translation termination";"Mitochondrial translation initiation";"Lipopolysaccharide biosynthesis";"CMP-3-deoxy-D-manno-octulosonate biosynthesis" JAMg_model_6031.1 8 Reactome: R-HSA-5358565;Reactome: R-HSA-983189;Reactome: R-HSA-6796648;Reactome: R-HSA-5545483;Reactome: R-HSA-912446;Reactome: R-HSA-6811434;Reactome: R-HSA-5632987;Reactome: R-HSA-5358606 "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Kinesins";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MLH1";"Meiotic recombination";"COPI-dependent Golgi-to-ER retrograde traffic";"Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)" JAMg_model_8897.4 3 Reactome: R-HSA-1268020;Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Mitochondrial protein import";"Respiratory electron transport";"Complex I biogenesis" JAMg_model_13435.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_11740.3 9 Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-6784531;Reactome: R-HSA-174430 "Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"Polymerase switching";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"tRNA processing in the nucleus";"Telomere C-strand synthesis initiation" JAMg_model_11294.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-429958 "Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease" JAMg_model_1614.1 2 Reactome: R-HSA-195253;Reactome: R-HSA-5689896 "Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases" JAMg_model_21252.3 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" JAMg_model_19116.4 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_11705.3 6 MetaCyc: PWY-7234;KEGG: 00230+4.1.1.21;Reactome: R-HSA-73817;KEGG: 00230+6.3.2.6;MetaCyc: PWY-6123;MetaCyc: PWY-6124 "Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II" JAMg_model_18821.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" JAMg_model_13380.3 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" JAMg_model_15492.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" JAMg_model_20576.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" JAMg_model_5221.1 6 Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" JAMg_model_14920.1 8 KEGG: 05163+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"Signaling by Hippo";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway" JAMg_model_20236.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" JAMg_model_20861.1 6 Reactome: R-HSA-110373;Reactome: R-HSA-73933;Reactome: R-HSA-5651801;Reactome: R-HSA-73930;Reactome: R-HSA-110357;Reactome: R-HSA-110362 "Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Resolution of Abasic Sites (AP sites)";"PCNA-Dependent Long Patch Base Excision Repair";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Displacement of DNA glycosylase by APEX1";"POLB-Dependent Long Patch Base Excision Repair" JAMg_model_4539.3 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" JAMg_model_20894.1 10 Reactome: R-HSA-2206292;Reactome: R-HSA-2024096;MetaCyc: PWY-6807;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00052+3.2.1.23 "MPS VII - Sly syndrome";"HS-GAG degradation";"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Other glycan degradation";"Neutrophil degranulation";"Galactose metabolism" JAMg_model_11069.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" JAMg_model_21270.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_8210.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695 "Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex" JAMg_model_18117.8 12 KEGG: 00380+2.6.1.7;MetaCyc: PWY-601;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6309;MetaCyc: PWY-6936;MetaCyc: PWY-1187;KEGG: 00270+4.4.1.13;Reactome: R-HSA-71240;MetaCyc: PWY-801;MetaCyc: PWY-7901;MetaCyc: PWY-2821;MetaCyc: PWY-6842 "Tryptophan metabolism";"Glucosinolate biosynthesis from tryptophan";"Selenocompound metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from homomethionine";"Cysteine and methionine metabolism";"Tryptophan catabolism";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from phenylalanine";"Glutathione-mediated detoxification II" JAMg_model_11737.1 1 Reactome: R-HSA-400253 "Circadian Clock" JAMg_model_6817.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" JAMg_model_13316.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_1706.2 3 Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121 "Translesion synthesis by REV1";"Translesion synthesis by POLK";"Translesion synthesis by POLI" JAMg_model_1629.3 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" JAMg_model_17319.2 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" JAMg_model_16891.1 1 Reactome: R-HSA-74217 "Purine salvage" JAMg_model_405.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" JAMg_model_17161.5 5 MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527 "D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Galactose metabolism";"Stachyose degradation" JAMg_model_11665.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" JAMg_model_14821.2 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" JAMg_model_17627.1 2 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol" JAMg_model_9684.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_8453.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" JAMg_model_7286.1 43 Reactome: R-HSA-8854518;Reactome: R-HSA-5467340;Reactome: R-HSA-163685;Reactome: R-HSA-5620912;Reactome: R-HSA-196299;Reactome: R-HSA-2565942;Reactome: R-HSA-195253;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-380270;Reactome: R-HSA-432142;Reactome: R-HSA-2995383;Reactome: R-HSA-5358747;Reactome: R-HSA-69273;Reactome: R-HSA-4641262;Reactome: R-HSA-380320;Reactome: R-HSA-202670;Reactome: R-HSA-5675221;Reactome: R-HSA-5467337;Reactome: R-HSA-68877;Reactome: R-HSA-5358752;Reactome: R-HSA-380284;Reactome: R-HSA-180024;Reactome: R-HSA-5467348;Reactome: R-HSA-389513;Reactome: R-HSA-69231;Reactome: R-HSA-975957;Reactome: R-HSA-5673000;Reactome: R-HSA-6811558;Reactome: R-HSA-5339716;Reactome: R-HSA-9634600;Reactome: R-HSA-1295596;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-2465910;Reactome: R-HSA-380259;Reactome: R-HSA-2500257;Reactome: R-HSA-6804757;Reactome: R-HSA-198753;Reactome: R-HSA-5358749;Reactome: R-HSA-113501;Reactome: R-HSA-163767 "AURKA Activation by TPX2";"AXIN missense mutants destabilize the destruction complex";"Integration of energy metabolism";"Anchoring of the basal body to the plasma membrane";"Beta-catenin phosphorylation cascade";"Regulation of PLK1 Activity at G2/M Transition";"Degradation of beta-catenin by the destruction complex";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Recruitment of mitotic centrosome proteins and complexes";"Platelet sensitization by LDL";"Initiation of Nuclear Envelope Reformation";"S33 mutants of beta-catenin aren't phosphorylated";"Cyclin A/B1/B2 associated events during G2/M transition";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Recruitment of NuMA to mitotic centrosomes";"ERKs are inactivated";"Negative regulation of MAPK pathway";"APC truncation mutants have impaired AXIN binding";"Mitotic Prometaphase";"T41 mutants of beta-catenin aren't phosphorylated";"Loss of proteins required for interphase microtubule organization from the centrosome";"DARPP-32 events";"Truncations of AMER1 destabilize the destruction complex";"CTLA4 inhibitory signaling";"Cyclin D associated events in G1";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RAF activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Spry regulation of FGF signaling";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"MASTL Facilitates Mitotic Progression";"Loss of Nlp from mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Regulation of TP53 Degradation";"ERK/MAPK targets";"S37 mutants of beta-catenin aren't phosphorylated";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"PP2A-mediated dephosphorylation of key metabolic factors" JAMg_model_4351.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" JAMg_model_5088.3 16 MetaCyc: PWY-1042;MetaCyc: PWY-6901;MetaCyc: PWY-7124;MetaCyc: PWY-7218;MetaCyc: PWY-2221;MetaCyc: PWY-6142;KEGG: 00010+4.2.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-1622;MetaCyc: PWY-8004;MetaCyc: PWY-6886;MetaCyc: PWY-5723;Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-7003;KEGG: 00680+4.2.1.11 "Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Ethylene biosynthesis V (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Rubisco shunt";"Gluconeogenesis";"Glycolysis";"Glycerol degradation to butanol";"Methane metabolism" JAMg_model_5433.2 4 Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556 "Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes" JAMg_model_4828.5 3 Reactome: R-HSA-525793;Reactome: R-HSA-5663220;Reactome: R-HSA-9634638 "Myogenesis";"RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling" JAMg_model_17580.4 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" JAMg_model_1845.1 3 MetaCyc: PWY-7942;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7 "5-oxo-L-proline metabolism";"Glutathione synthesis and recycling";"Glutathione metabolism" JAMg_model_5266.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_13658.2 3 MetaCyc: PWY-7999;KEGG: 00130+1.17.4.4;Reactome: R-HSA-6806664 "Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Metabolism of vitamin K" JAMg_model_20656.1 24 Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-9648025;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"EML4 and NUDC in mitotic spindle formation";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"HCMV Early Events";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin" JAMg_model_6562.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_10598.4 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5689880 "UCH proteinases";"Ub-specific processing proteases" JAMg_model_16589.4 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" JAMg_model_4027.1 6 Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-212676 "Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" JAMg_model_10401.2 3 Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-5689877 "Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"Josephin domain DUBs" JAMg_model_4807.2 4 Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825 "Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis" JAMg_model_13545.2 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" JAMg_model_8435.3 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_8210.3 6 Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72695 "Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex" JAMg_model_6324.5 10 KEGG: 00561+2.3.1.15;KEGG: 00564+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-8053 "Glycerolipid metabolism";"Glycerophospholipid metabolism";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II" JAMg_model_6097.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" JAMg_model_1964.3 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" JAMg_model_16071.2 9 Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-114608;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948 "Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Platelet degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants" JAMg_model_7772.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" JAMg_model_20854.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259 "Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism" JAMg_model_17000.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" JAMg_model_4469.1 33 Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-1169408;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-5663220;Reactome: R-HSA-4085377;Reactome: R-HSA-141444;Reactome: R-HSA-159236 "Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"RHO GTPases Activate Formins";"SUMOylation of SUMOylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA derived from an Intron-Containing Transcript" JAMg_model_16329.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" JAMg_model_12899.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" JAMg_model_20787.7 32 Reactome: R-HSA-75953;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-72203;Reactome: R-HSA-6803529;Reactome: R-HSA-76042;Reactome: R-HSA-9018519;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-168325;Reactome: R-HSA-6807505;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-167172;Reactome: R-HSA-8851708;Reactome: R-HSA-77075 "RNA Polymerase II Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Capped Intron-Containing Pre-mRNA";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Estrogen-dependent gene expression";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Viral Messenger RNA Synthesis";"RNA polymerase II transcribes snRNA genes";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"Transcription of the HIV genome";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE" JAMg_model_218.2 1 Reactome: R-HSA-73621 "Pyrimidine catabolism" JAMg_model_10139.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" JAMg_model_11689.2 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" JAMg_model_1687.1 16 Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-174184;Reactome: R-HSA-176409;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-174084 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C" JAMg_model_18312.2 29 Reactome: R-HSA-5696397;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-174437;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-69166;Reactome: R-HSA-6782210;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-3371453;Reactome: R-HSA-5696395;Reactome: R-HSA-5685938;Reactome: R-HSA-3371511;Reactome: R-HSA-3108214;Reactome: R-HSA-912446;Reactome: R-HSA-5655862;Reactome: R-HSA-6783310;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-6804756 "Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate from the C-strand";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Regulation of HSF1-mediated heat shock response";"Formation of Incision Complex in GG-NER";"HDR through Single Strand Annealing (SSA)";"HSF1 activation";"SUMOylation of DNA damage response and repair proteins";"Meiotic recombination";"Translesion synthesis by POLK";"Fanconi Anemia Pathway";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of TP53 Activity through Phosphorylation" JAMg_model_13242.1 7 KEGG: 00471+3.5.1.2;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539 "D-Glutamine and D-glutamate metabolism";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism" JAMg_model_3523.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" JAMg_model_10328.3 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" JAMg_model_8631.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" JAMg_model_3411.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" JAMg_model_15951.1 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" JAMg_model_7521.2 2 Reactome: R-HSA-5693554;Reactome: R-HSA-2564830 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Cytosolic iron-sulfur cluster assembly" JAMg_model_3870.2 2 Reactome: R-HSA-3065676;Reactome: R-HSA-3065678 "SUMO is conjugated to E1 (UBA2:SAE1)";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)" JAMg_model_1475.2 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" JAMg_model_17959.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" JAMg_model_13411.1 4 Reactome: R-HSA-912631;Reactome: R-HSA-8875555;Reactome: R-HSA-186763;Reactome: R-HSA-8875656 "Regulation of signaling by CBL";"MET activates RAP1 and RAC1";"Downstream signal transduction";"MET receptor recycling" JAMg_model_13588.4 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_4539.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" JAMg_model_2739.1 11 Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-174430;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-68952;Reactome: R-HSA-5696400;Reactome: R-HSA-68962;Reactome: R-HSA-5696397 "PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Telomere C-strand synthesis initiation";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"DNA replication initiation";"Dual Incision in GG-NER";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in GG-NER" JAMg_model_1425.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825 "DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis" JAMg_model_18359.2 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" JAMg_model_20179.1 8 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-418889;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Caspase activation via Dependence Receptors in the absence of ligand";"Relaxin signaling pathway" JAMg_model_7037.2 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" JAMg_model_8725.2 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" JAMg_model_651.2 3 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.5;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" JAMg_model_16361.1 5 Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390471 "Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis" JAMg_model_16886.3 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" JAMg_model_5172.1 1 Reactome: R-HSA-211981 "Xenobiotics" JAMg_model_7638.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_8700.3 8 Reactome: R-HSA-380972;Reactome: R-HSA-6798695;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897 "Energy dependent regulation of mTOR by LKB1-AMPK";"Neutrophil degranulation";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Macroautophagy";"mTOR signalling";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes" JAMg_model_1274.4 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" JAMg_model_11121.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-176187 "Activation of the pre-replicative complex";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress" JAMg_model_5689.1 2 Reactome: R-HSA-191859;Reactome: R-HSA-6807505 "snRNP Assembly";"RNA polymerase II transcribes snRNA genes" JAMg_model_4541.2 7 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2" JAMg_model_1335.1 7 Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232 "Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants" JAMg_model_1335.4 7 Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus" JAMg_model_2560.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_15697.1 57 Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-6798695;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-5607764 "Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Degradation of GLI2 by the proteasome";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Neutrophil degranulation";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling" JAMg_model_6625.1 4 Reactome: R-HSA-156581;Reactome: R-HSA-6790901;Reactome: R-HSA-6782315;Reactome: R-HSA-72764 "Methylation";"rRNA modification in the nucleus and cytosol";"tRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination" JAMg_model_14039.3 7 KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;MetaCyc: PWY-8052;MetaCyc: PWY-7039 "Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule" JAMg_model_18133.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_18237.1 3 Reactome: R-HSA-983231;Reactome: R-HSA-6798695;Reactome: R-HSA-164944 "Factors involved in megakaryocyte development and platelet production";"Neutrophil degranulation";"Nef and signal transduction" JAMg_model_12934.2 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" JAMg_model_4053.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-162658 "COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization" JAMg_model_15367.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" JAMg_model_8512.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" JAMg_model_17542.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" JAMg_model_17401.2 1 Reactome: R-HSA-6799198 "Complex I biogenesis" JAMg_model_9084.4 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" JAMg_model_13543.1 3 Reactome: R-HSA-6787450;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470 "tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion" JAMg_model_61.1 5 Reactome: R-HSA-5579026;Reactome: R-HSA-1362409;Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-196108 "Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis" JAMg_model_7489.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_15652.1 3 Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857 "Digestion of dietary lipid";"Glycerolipid metabolism";"Retinol biosynthesis" JAMg_model_12508.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" JAMg_model_8369.1 3 Reactome: R-HSA-2142700;Reactome: R-HSA-2142691;KEGG: 00970+6.3.5.7 "Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aminoacyl-tRNA biosynthesis" JAMg_model_7209.1 56 Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-180585;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-1236978;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-382556 "Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"FCERI mediated NF-kB activation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Vif-mediated degradation of APOBEC3G";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"ABC-family proteins mediated transport" JAMg_model_2074.2 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" JAMg_model_11034.2 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" JAMg_model_2682.1 2 Reactome: R-HSA-190873;Reactome: R-HSA-399719 "Gap junction degradation";"Trafficking of AMPA receptors" JAMg_model_4485.2 4 Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437 "UCH proteinases";"HATs acetylate histones";"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation" JAMg_model_9210.1 8 Reactome: R-HSA-5628897;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-9613354;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-6804756;Reactome: R-HSA-380972 "TP53 Regulates Metabolic Genes";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Lipophagy";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK" JAMg_model_19649.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" JAMg_model_5561.4 5 Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling" JAMg_model_13622.1 10 KEGG: 00332+1.2.1.41;KEGG: 00330+2.7.2.11;Reactome: R-HSA-8964539;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00332+2.7.2.11+1.2.1.41;MetaCyc: PWY-6922;KEGG: 00330+1.2.1.41;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+2.7.2.11;KEGG: 00332+1.2.1.41+2.7.2.11 "Carbapenem biosynthesis";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis" JAMg_model_20801.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" JAMg_model_11007.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" JAMg_model_5069.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_4090.2 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" JAMg_model_4768.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" JAMg_model_3148.4 8 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Signaling by Hippo";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis" JAMg_model_2804.1 5 Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-389357 "VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling" JAMg_model_650.3 4 KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;Reactome: R-HSA-351202 "Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Metabolism of polyamines" JAMg_model_19213.2 3 Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51 "Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation" JAMg_model_16115.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_13255.1 7 Reactome: R-HSA-1221632;Reactome: R-HSA-2559586;Reactome: R-HSA-110328;Reactome: R-HSA-110330;Reactome: R-HSA-171306;Reactome: R-HSA-110329;Reactome: R-HSA-110331 "Meiotic synapsis";"DNA Damage/Telomere Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Packaging Of Telomere Ends";"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine" JAMg_model_19888.2 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_7189.7 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" JAMg_model_10492.3 1 Reactome: R-HSA-110357 "Displacement of DNA glycosylase by APEX1" JAMg_model_4485.1 4 Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437;Reactome: R-HSA-5689603 "HATs acetylate histones";"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases" JAMg_model_10201.2 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_3662.4 16 Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Peptide chain elongation";"Viral mRNA Translation" JAMg_model_9396.3 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" JAMg_model_9535.1 29 Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693571;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-6803204;Reactome: R-HSA-5693548;Reactome: R-HSA-5693579;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2559586;Reactome: R-HSA-6804757;Reactome: R-HSA-6804756;Reactome: R-HSA-6803207;Reactome: R-HSA-5693565;KEGG: 05170+2.7.11.1;Reactome: R-HSA-912446;Reactome: R-HSA-6804760;Reactome: R-HSA-349425;Reactome: R-HSA-69541;Reactome: R-HSA-3371453;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693554;Reactome: R-HSA-6796648;Reactome: R-HSA-5685938 "HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Nonhomologous End-Joining (NHEJ)";"PI3K-Akt signaling pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Sensing of DNA Double Strand Breaks";"Homologous DNA Pairing and Strand Exchange";"Thermogenesis";"DNA Damage/Telomere Stress Induced Senescence";"Regulation of TP53 Degradation";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Human immunodeficiency virus 1 infection";"Meiotic recombination";"Regulation of TP53 Activity through Methylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Stabilization of p53";"Regulation of HSF1-mediated heat shock response";"Human cytomegalovirus infection";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"TP53 Regulates Transcription of DNA Repair Genes";"HDR through Single Strand Annealing (SSA)" JAMg_model_21260.6 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" JAMg_model_361.6 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" JAMg_model_5838.1 5 MetaCyc: PWY-7279;KEGG: 00190+7.1.1.8;MetaCyc: PWY-6692;MetaCyc: PWY-3781;MetaCyc: PWY-7082 "Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation";"Fe(II) oxidation";"Aerobic respiration I (cytochrome c)";"Ammonia oxidation IV (autotrophic ammonia oxidizers)" JAMg_model_6601.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" JAMg_model_21356.3 9 Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-75953 "RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation" JAMg_model_8020.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" JAMg_model_15493.1 20 MetaCyc: PWY-735;MetaCyc: PWY-7854;MetaCyc: PWY-7291;MetaCyc: PWY-7338;MetaCyc: PWY-7288;MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7337;Reactome: R-HSA-9033241;MetaCyc: PWY-5136;MetaCyc: PWY-6920;MetaCyc: PWY-7340;MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6 "Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Peroxisomal protein import";"Fatty acid beta-oxidation II (plant peroxisome)";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism" JAMg_model_7088.1 3 MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21 "Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system" JAMg_model_14361.1 4 MetaCyc: PWY-5028;KEGG: 00340+4.2.1.49;MetaCyc: PWY-5030;Reactome: R-HSA-70921 "L-histidine degradation II";"Histidine metabolism";"L-histidine degradation III";"Histidine catabolism" JAMg_model_5161.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556 "Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes" JAMg_model_4386.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" JAMg_model_5442.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" JAMg_model_6599.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" JAMg_model_4116.5 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" JAMg_model_17866.1 1 Reactome: R-HSA-1632852 "Macroautophagy" JAMg_model_14261.2 3 Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161 "Metabolism of folate and pterines";"Folate biosynthesis";"Folate polyglutamylation" JAMg_model_20613.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_7979.3 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" JAMg_model_3715.5 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_7900.2 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" JAMg_model_16555.1 15 MetaCyc: PWY-5723;MetaCyc: PWY-2221;MetaCyc: PWY-8004;MetaCyc: PWY-6886;MetaCyc: PWY-7218;MetaCyc: PWY-7383;MetaCyc: PWY-6901;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.40;MetaCyc: PWY-1042;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6142;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7003;Reactome: R-HSA-70171 "Rubisco shunt";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Purine metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pyruvate metabolism";"Glycerol degradation to butanol";"Glycolysis" JAMg_model_18243.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-171319 "Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase" JAMg_model_10520.1 5 KEGG: 00510+1.3.1.94;MetaCyc: PWY-6129;Reactome: R-HSA-4755579;Reactome: R-HSA-446199;Reactome: R-HSA-193048 "N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Synthesis of Dolichyl-phosphate";"Androgen biosynthesis" JAMg_model_11395.3 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" JAMg_model_7100.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" JAMg_model_12490.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism" JAMg_model_824.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" JAMg_model_16886.2 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" JAMg_model_10741.2 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" JAMg_model_219.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" JAMg_model_10683.1 1 Reactome: R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" JAMg_model_7963.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827 "Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression" JAMg_model_9593.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_3265.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" JAMg_model_7739.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" JAMg_model_12509.1 1 Reactome: R-HSA-73943 "Reversal of alkylation damage by DNA dioxygenases" JAMg_model_12515.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" JAMg_model_6648.1 4 Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216 "Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization" JAMg_model_4807.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394 "Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER" JAMg_model_17757.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" JAMg_model_3789.2 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" JAMg_model_1151.4 1 Reactome: R-HSA-8950505 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" JAMg_model_4580.2 7 MetaCyc: PWY-8026;Reactome: R-HSA-9022692;MetaCyc: PWY-7154;MetaCyc: PWY-2541;MetaCyc: PWY-6074;Reactome: R-HSA-191273;KEGG: 00100+1.3.1.70 "Sterol biosynthesis (methylotrophs)";"Regulation of MECP2 expression and activity";"Ergosterol biosynthesis II";"Phytosterol biosynthesis (plants)";"Zymosterol biosynthesis";"Cholesterol biosynthesis";"Steroid biosynthesis" JAMg_model_18596.1 3 KEGG: 00600+3.1.4.12;MetaCyc: PWY-7277;Reactome: R-HSA-1660662 "Sphingolipid metabolism";"Sphingolipid biosynthesis (mammals)";"Glycosphingolipid metabolism" JAMg_model_7843.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" JAMg_model_19961.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-8953750 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional Regulation by E2F6" JAMg_model_15471.1 57 Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-75815;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-6798695;Reactome: R-HSA-1169091;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-5607761 "Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Neutrophil degranulation";"Activation of NF-kappaB in B cells";"UCH proteinases";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling" JAMg_model_16672.1 3 Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" JAMg_model_14641.2 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" JAMg_model_1225.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" JAMg_model_15597.1 40 Reactome: R-HSA-6782135;Reactome: R-HSA-73776;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-167162;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-9018519;Reactome: R-HSA-76042;Reactome: R-HSA-5601884;Reactome: R-HSA-6803529;Reactome: R-HSA-72203;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-6807505;Reactome: R-HSA-168325;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167160;Reactome: R-HSA-5578749;Reactome: R-HSA-72163;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-203927;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-77075;Reactome: R-HSA-8851708;Reactome: R-HSA-5617472;Reactome: R-HSA-167172;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-6781823;Reactome: R-HSA-167238;Reactome: R-HSA-72086 "Dual incision in TC-NER";"RNA Polymerase II Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II HIV Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"PIWI-interacting RNA (piRNA) biogenesis";"FGFR2 alternative splicing";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA polymerase II transcribes snRNA genes";"Viral Messenger RNA Synthesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcriptional regulation by small RNAs";"mRNA Splicing - Major Pathway";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"MicroRNA (miRNA) biogenesis";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Signaling by FGFR2 IIIa TM";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcription of the HIV genome";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"Formation of TC-NER Pre-Incision Complex";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Capping" JAMg_model_20881.2 16 Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764 "L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination" JAMg_model_7287.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" JAMg_model_5024.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" JAMg_model_2066.1 4 Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828 "EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis" JAMg_model_6531.1 10 MetaCyc: PWY-6369;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6372;Reactome: R-HSA-1855191;MetaCyc: PWY-6362;Reactome: R-HSA-1855167;MetaCyc: PWY-4661;MetaCyc: PWY-6554;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6361 "Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)" JAMg_model_18594.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-6798695;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Clathrin-mediated endocytosis";"Neutrophil degranulation";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" JAMg_model_583.9 1 Reactome: R-HSA-71384 "Ethanol oxidation" JAMg_model_12447.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" JAMg_model_16816.3 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" JAMg_model_14961.5 4 MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+2.8.1.8;Reactome: R-HSA-389661 "Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation" JAMg_model_931.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" JAMg_model_19043.1 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_10807.2 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_9186.8 6 MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508 "Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis" JAMg_model_18865.1 6 Reactome: R-HSA-977347;MetaCyc: PWY-8010;KEGG: 00270+2.6.1.52;KEGG: 00260+2.6.1.52;KEGG: 00680+2.6.1.52;KEGG: 00750+2.6.1.52 "Serine biosynthesis";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism";"Methane metabolism";"Vitamin B6 metabolism" JAMg_model_17610.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" JAMg_model_7002.2 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" JAMg_model_11987.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-164378 "Hedgehog 'off' state";"PKA activation";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (s) signalling events";"PKA activation in glucagon signalling" JAMg_model_4711.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" JAMg_model_266.1 13 KEGG: 00983+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7198;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-6545;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-7227;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7226;KEGG: 00480+1.17.4.1 "Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism" JAMg_model_17023.1 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" JAMg_model_15722.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" JAMg_model_6375.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_2157.3 1 Reactome: R-HSA-189451 "Heme biosynthesis" JAMg_model_11842.2 17 Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6790901;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827 "Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression" JAMg_model_15201.1 10 Reactome: R-HSA-8934903;Reactome: R-HSA-6814122;Reactome: R-HSA-6804756;Reactome: R-HSA-6798695;Reactome: R-HSA-201688;Reactome: R-HSA-8939243;Reactome: R-HSA-1483191;Reactome: R-HSA-2514853;Reactome: R-HSA-8948751;Reactome: R-HSA-445144 "Receptor Mediated Mitophagy";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of TP53 Activity through Phosphorylation";"Neutrophil degranulation";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Synthesis of PC";"Condensation of Prometaphase Chromosomes";"Regulation of PTEN stability and activity";"Signal transduction by L1" JAMg_model_811.1 8 MetaCyc: PWY-7400;MetaCyc: PWY-5;MetaCyc: PWY-5154;Reactome: R-HSA-70635;MetaCyc: PWY-4984;KEGG: 00250+6.3.4.5;KEGG: 00220+6.3.4.5;MetaCyc: PWY-4983 "L-arginine biosynthesis IV (archaebacteria)";"Canavanine biosynthesis";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Urea cycle";"Urea cycle";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Nitric oxide biosynthesis II (mammals)" JAMg_model_4275.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" JAMg_model_19218.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214815 "NoRC negatively regulates rRNA expression";"HDACs deacetylate histones" JAMg_model_19199.2 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" JAMg_model_4116.10 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" JAMg_model_4371.1 5 Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-6798695;Reactome: R-HSA-164843;Reactome: R-HSA-3270619 "Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"Neutrophil degranulation";"2-LTR circle formation";"IRF3-mediated induction of type I IFN" JAMg_model_17269.3 3 Reactome: R-HSA-6782315;MetaCyc: PWY-8106;MetaCyc: PWY-6700 "tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)" JAMg_model_3324.1 3 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15;Reactome: R-HSA-5628897 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism";"TP53 Regulates Metabolic Genes" JAMg_model_2059.5 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_17277.2 6 MetaCyc: PWY-5723;KEGG: 00710+5.1.3.1;KEGG: 00030+5.1.3.1;MetaCyc: PWY-1861;KEGG: 00040+5.1.3.1;Reactome: R-HSA-71336 "Rubisco shunt";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose and glucuronate interconversions";"Pentose phosphate pathway" JAMg_model_14914.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270 "AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" JAMg_model_10713.4 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" JAMg_model_11092.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_13140.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_8477.5 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" JAMg_model_11713.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_15860.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" JAMg_model_16773.1 27 Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-159231;Reactome: R-HSA-3301854 "ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly" JAMg_model_3669.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" JAMg_model_15277.6 10 MetaCyc: PWY-5030;Reactome: R-HSA-196757;MetaCyc: PWY-6613;MetaCyc: PWY-7909;MetaCyc: PWY-3841;MetaCyc: PWY-5497;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722 "L-histidine degradation III";"Metabolism of folate and pterines";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Formate assimilation into 5,10-methylenetetrahydrofolate" JAMg_model_13234.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" JAMg_model_446.3 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_17792.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" JAMg_model_15187.2 5 Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-5625740 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs" JAMg_model_5303.2 4 Reactome: R-HSA-4755583;Reactome: R-HSA-446199;KEGG: 00510+2.7.1.108;MetaCyc: PWY-6129 "Defective DOLK causes DOLK-CDG (CDG-1m)";"Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis" JAMg_model_21184.1 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" JAMg_model_8153.4 3 KEGG: 00260+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3 "Glycine, serine and threonine metabolism";"Serine biosynthesis";"Methane metabolism" JAMg_model_5158.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" JAMg_model_6979.1 13 Reactome: R-HSA-3371511;Reactome: R-HSA-9646399;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-5689896;Reactome: R-HSA-8876725;Reactome: R-HSA-532668;Reactome: R-HSA-5678895;Reactome: R-HSA-6798695;Reactome: R-HSA-5689877;Reactome: R-HSA-110320;Reactome: R-HSA-382556;Reactome: R-HSA-8866654 "HSF1 activation";"Aggrephagy";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Ovarian tumor domain proteases";"Protein methylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Defective CFTR causes cystic fibrosis";"Neutrophil degranulation";"Josephin domain DUBs";"Translesion Synthesis by POLH";"ABC-family proteins mediated transport";"E3 ubiquitin ligases ubiquitinate target proteins" JAMg_model_11008.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" JAMg_model_2627.1 2 KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111 "Fatty acid degradation";"Mitochondrial L-carnitine shuttle" JAMg_model_14591.3 22 Reactome: R-HSA-2500257;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025;Reactome: R-HSA-4641262;Reactome: R-HSA-2467813;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-5358752;Reactome: R-HSA-68877;Reactome: R-HSA-5467337;Reactome: R-HSA-5675221;Reactome: R-HSA-5358749;Reactome: R-HSA-196299;Reactome: R-HSA-5673000;Reactome: R-HSA-5467340;Reactome: R-HSA-389513;Reactome: R-HSA-432142;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-6811558;Reactome: R-HSA-195253;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Separation of Sister Chromatids";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"APC truncation mutants have impaired AXIN binding";"Negative regulation of MAPK pathway";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"RAF activation";"AXIN missense mutants destabilize the destruction complex";"CTLA4 inhibitory signaling";"Platelet sensitization by LDL";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Degradation of beta-catenin by the destruction complex";"RHO GTPases Activate Formins" JAMg_model_7884.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_14414.2 3 Reactome: R-HSA-1660662;Reactome: R-HSA-5626978;Reactome: R-HSA-193681 "Glycosphingolipid metabolism";"TNFR1-mediated ceramide production";"Ceramide signalling" JAMg_model_11442.3 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" JAMg_model_20059.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_2157.2 1 Reactome: R-HSA-189451 "Heme biosynthesis" JAMg_model_5212.1 4 MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546;Reactome: R-HSA-8849175 "Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)";"Threonine catabolism" JAMg_model_7256.2 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" JAMg_model_14124.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" JAMg_model_8550.8 14 MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7035;Reactome: R-HSA-75876 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs" JAMg_model_9685.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_20955.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" JAMg_model_4828.2 3 Reactome: R-HSA-5663220;Reactome: R-HSA-9634638;Reactome: R-HSA-525793 "RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis" JAMg_model_1293.2 6 MetaCyc: PWY-1622;MetaCyc: PWY-8004;MetaCyc: PWY-5484;KEGG: 00680+5.4.2.11;KEGG: 00010+5.4.2.11;KEGG: 00260+5.4.2.11 "Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Glycine, serine and threonine metabolism" JAMg_model_7094.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_10824.4 12 KEGG: 00230+2.7.1.25;MetaCyc: PWY-5278;KEGG: 00920+2.7.7.4;Reactome: R-HSA-2408550;Reactome: R-HSA-174362;KEGG: 00450+2.7.7.4;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5340;MetaCyc: PWY-6683;KEGG: 00230+2.7.7.4;KEGG: 00920+2.7.1.25;MetaCyc: PWY-6932 "Purine metabolism";"Sulfite oxidation III";"Sulfur metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Transport and synthesis of PAPS";"Selenocompound metabolism";"Monobactam biosynthesis";"Sulfate activation for sulfonation";"Assimilatory sulfate reduction III";"Purine metabolism";"Sulfur metabolism";"Selenate reduction" JAMg_model_9515.2 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_1877.1 14 Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-110312;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-5696397 "Translesion synthesis by POLK";"Polymerase switching";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Translesion synthesis by REV1";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER" JAMg_model_15508.2 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" JAMg_model_13056.6 13 Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis" JAMg_model_13403.2 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" JAMg_model_11686.2 7 Reactome: R-HSA-983170;Reactome: R-HSA-3371453;Reactome: R-HSA-381183;Reactome: R-HSA-114608;Reactome: R-HSA-381042;Reactome: R-HSA-381070;Reactome: R-HSA-381033 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of HSF1-mediated heat shock response";"ATF6 (ATF6-alpha) activates chaperone genes";"Platelet degranulation";"PERK regulates gene expression";"IRE1alpha activates chaperones";"ATF6 (ATF6-alpha) activates chaperones" JAMg_model_14760.1 2 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Synthesis of PG";"Synthesis of PA" JAMg_model_9652.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" JAMg_model_5776.2 3 Reactome: R-HSA-1614603;Reactome: R-HSA-2408508;Reactome: R-HSA-1614558 "Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine" JAMg_model_1117.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_10701.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" JAMg_model_4871.2 4 MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14 "Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism" JAMg_model_197.2 29 Reactome: R-HSA-427413;Reactome: R-HSA-167160;Reactome: R-HSA-167161;Reactome: R-HSA-5696400;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-73772;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-5696395;Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-73863 "NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV Transcription Initiation";"Dual Incision in GG-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Promoter Escape";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination" JAMg_model_17071.2 44 Reactome: R-HSA-5674135;Reactome: R-HSA-445144;Reactome: R-HSA-1295596;Reactome: R-HSA-5663213;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-444257;Reactome: R-HSA-2029482;Reactome: R-HSA-74749;Reactome: R-HSA-198753;Reactome: R-HSA-170968;Reactome: R-HSA-982772;Reactome: R-HSA-881907;Reactome: R-HSA-2559585;Reactome: R-HSA-6802948;Reactome: R-HSA-9634638;Reactome: R-HSA-9635465;Reactome: R-HSA-5654733;Reactome: R-HSA-8943724;Reactome: R-HSA-9627069;Reactome: R-HSA-162658;Reactome: R-HSA-5654727;KEGG: 04150+2.7.11.24;Reactome: R-HSA-9649948;Reactome: R-HSA-8940973;Reactome: R-HSA-6802952;Reactome: R-HSA-5654726;Reactome: R-HSA-450341;Reactome: R-HSA-456926;Reactome: R-HSA-2559582;Reactome: R-HSA-5654732;Reactome: R-HSA-5668599;Reactome: R-HSA-5675221;Reactome: R-HSA-3371453;Reactome: R-HSA-2559580;Reactome: R-HSA-8939211;Reactome: R-HSA-879415;Reactome: R-HSA-2871796;Reactome: R-HSA-202670;Reactome: R-HSA-375165;Reactome: R-HSA-112409;Reactome: R-HSA-5674499 "MAP2K and MAPK activation";"Signal transduction by L1";"Spry regulation of FGF signaling";"RHO GTPases Activate WASPs and WAVEs";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"RSK activation";"Regulation of actin dynamics for phagocytic cup formation";"Signal attenuation";"ERK/MAPK targets";"Frs2-mediated activation";"Growth hormone receptor signaling";"Gastrin-CREB signalling pathway via PKC and MAPK";"Oncogene Induced Senescence";"Signaling by high-kinase activity BRAF mutants";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Suppression of apoptosis";"Negative regulation of FGFR4 signaling";"Regulation of PTEN gene transcription";"Regulation of the apoptosome activity";"Golgi Cisternae Pericentriolar Stack Reorganization";"Negative regulation of FGFR2 signaling";"mTOR signaling pathway";"Signaling downstream of RAS mutants";"RUNX2 regulates osteoblast differentiation";"Signaling by BRAF and RAF fusions";"Negative regulation of FGFR1 signaling";"Activation of the AP-1 family of transcription factors";"Thrombin signalling through proteinase activated receptors (PARs)";"Senescence-Associated Secretory Phenotype (SASP)";"Negative regulation of FGFR3 signaling";"RHO GTPases Activate NADPH Oxidases";"Negative regulation of MAPK pathway";"Regulation of HSF1-mediated heat shock response";"Oxidative Stress Induced Senescence";"ESR-mediated signaling";"Advanced glycosylation endproduct receptor signaling";"FCERI mediated MAPK activation";"ERKs are inactivated";"NCAM signaling for neurite out-growth";"RAF-independent MAPK1/3 activation";"Negative feedback regulation of MAPK pathway" JAMg_model_5764.2 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" JAMg_model_9993.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" JAMg_model_6423.1 7 KEGG: 00051+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00680+3.1.3.11;KEGG: 00010+3.1.3.11;KEGG: 00030+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00710+3.1.3.11 "Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms" JAMg_model_1450.2 13 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706 "Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit" JAMg_model_7421.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" JAMg_model_4567.2 7 KEGG: 00010+1.2.4.1;KEGG: 00020+1.2.4.1;Reactome: R-HSA-389661;Reactome: R-HSA-70268;KEGG: 00620+1.2.4.1;Reactome: R-HSA-204174;Reactome: R-HSA-5362517 "Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid" JAMg_model_14875.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_2132.4 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" JAMg_model_16428.1 4 KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803 "alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing" JAMg_model_21029.4 15 Reactome: R-HSA-195253;Reactome: R-HSA-5358749;Reactome: R-HSA-5467333;Reactome: R-HSA-5467337;Reactome: R-HSA-5689896;Reactome: R-HSA-111465;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-3769402;Reactome: R-HSA-4641262;Reactome: R-HSA-5467340;Reactome: R-HSA-5358751;Reactome: R-HSA-196299 "Degradation of beta-catenin by the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"APC truncation mutants have impaired AXIN binding";"Ovarian tumor domain proteases";"Apoptotic cleavage of cellular proteins";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"AXIN missense mutants destabilize the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade" JAMg_model_15812.4 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" JAMg_model_11240.1 10 KEGG: 00620+1.2.4.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-5362517;KEGG: 00020+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-389661;Reactome: R-HSA-8964208;Reactome: R-HSA-204174;KEGG: 00010+1.2.4.1;KEGG: 00460+3.5.1.1 "Pyruvate metabolism";"Alanine, aspartate and glutamate metabolism";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Phenylalanine metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycolysis / Gluconeogenesis";"Cyanoamino acid metabolism" JAMg_model_13125.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events" JAMg_model_11657.5 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" JAMg_model_13323.4 3 Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-110357 "Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1" JAMg_model_10973.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" JAMg_model_11799.1 13 MetaCyc: PWY-7410;MetaCyc: PWY-6383;MetaCyc: PWY-7736;MetaCyc: PWY-7659;MetaCyc: PWY-5123;MetaCyc: PWY-7141;MetaCyc: PWY-5122;MetaCyc: PWY-7102;MetaCyc: PWY-6859;MetaCyc: PWY-7721;MetaCyc: PWY-7709;MetaCyc: PWY-7182;KEGG: 00900+2.5.1.10+2.5.1.1 "Ipsdienol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Stellatic acid biosynthesis";"Viridicatumtoxin biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"(3S)-linalool biosynthesis";"Geranyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"All-trans-farnesol biosynthesis";"Methyl phomopsenoate biosynthesis";"(3R)-linalool biosynthesis";"Linalool biosynthesis I";"Terpenoid backbone biosynthesis" JAMg_model_15364.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" JAMg_model_8940.1 5 Reactome: R-HSA-380994;Reactome: R-HSA-8963693;Reactome: R-HSA-9633012;Reactome: R-HSA-9648895;KEGG: 00250+6.3.5.4 "ATF4 activates genes in response to endoplasmic reticulum stress";"Aspartate and asparagine metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Response of EIF2AK1 (HRI) to heme deficiency";"Alanine, aspartate and glutamate metabolism" JAMg_model_12041.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_15811.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_7046.1 4 KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3 "Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism" JAMg_model_6416.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" JAMg_model_17960.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" JAMg_model_7435.1 9 Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-76042 "RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance" JAMg_model_9122.1 1 Reactome: R-HSA-977443 "GABA receptor activation" JAMg_model_20397.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" JAMg_model_6221.1 18 Reactome: R-HSA-166208;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-6790901;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "mTORC1-mediated signalling";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Peptide chain elongation" JAMg_model_9895.2 10 MetaCyc: PWY-6317;MetaCyc: PWY-7344;MetaCyc: PWY-3821;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6527;Reactome: R-HSA-70370;MetaCyc: PWY-6397;Reactome: R-HSA-5609977;MetaCyc: PWY-7328;KEGG: 00520+5.1.3.2 "D-galactose degradation I (Leloir pathway)";"UDP-alpha-D-galactose biosynthesis";"D-galactose detoxification";"Galactose metabolism";"Stachyose degradation";"Galactose catabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Amino sugar and nucleotide sugar metabolism" JAMg_model_16071.6 9 Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-114608;Reactome: R-HSA-6798695;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135 "Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Platelet degranulation";"Neutrophil degranulation";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation" JAMg_model_12627.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" JAMg_model_650.1 4 KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202 "Glutathione metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines" JAMg_model_11907.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" JAMg_model_1124.6 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" JAMg_model_16705.1 14 MetaCyc: PWY-5981;MetaCyc: PWY-7589;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-7782;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-7417 "CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)" JAMg_model_13528.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" JAMg_model_8721.3 3 KEGG: 00531+3.2.1.50;Reactome: R-HSA-2024096;Reactome: R-HSA-2206282 "Glycosaminoglycan degradation";"HS-GAG degradation";"MPS IIIB - Sanfilippo syndrome B" JAMg_model_961.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" JAMg_model_14659.3 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" JAMg_model_2847.2 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" JAMg_model_12733.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_9911.2 12 Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-76061;Reactome: R-HSA-5250924;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73863;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-73762 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase I Transcription Initiation" JAMg_model_11239.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_18861.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" JAMg_model_3952.3 16 Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Viral mRNA Translation" JAMg_model_13365.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" JAMg_model_12633.2 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_18188.3 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" JAMg_model_1847.1 2 Reactome: R-HSA-163282;Reactome: R-HSA-2151201 "Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis" JAMg_model_16427.1 4 KEGG: 00473+5.1.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-8072;MetaCyc: PWY-8040 "D-Alanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine racemization";"Ansatrienin biosynthesis" JAMg_model_3049.1 42 MetaCyc: PWY-1361;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7216;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;MetaCyc: PWY-7606;KEGG: 00640+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;MetaCyc: PWY-6946;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;MetaCyc: PWY-6435;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;MetaCyc: PWY-7654;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;MetaCyc: PWY-6944;KEGG: 00903+4.2.1.17;KEGG: 00592+4.2.1.17;MetaCyc: PWY-7726;MetaCyc: PWY-7401;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;MetaCyc: PWY-5789;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-7656;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;MetaCyc: PWY-5177;MetaCyc: PWY-5138;KEGG: 00627+4.2.1.17;KEGG: 00410+4.2.1.17;KEGG: 00360+4.2.1.17 "Benzoyl-coa degradation I (aerobic)";"Toluene degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Carbon fixation pathways in prokaryotes";"Caprolactam degradation";"Methyl tert-butyl ether degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"Geraniol degradation";"Pyruvate fermentation to hexanol (engineered)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Fatty acid degradation";"Fatty acid salvage";"Butanoate metabolism";"2-methylpropene degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Butanoate metabolism";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fatty acid elongation";"Fatty acid beta-oxidation II (plant peroxisome)";"Benzoate degradation";"Tryptophan metabolism";"Methyl ketone biosynthesis (engineered)";"Androstenedione degradation";"Limonene and pinene degradation";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Fatty acid degradation";"Fermentation to 2-methylbutanoate";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Lysine degradation";"Pyruvate fermentation to butanol II (engineered)";"Spodoptera littoralis pheromone biosynthesis";"Valine, leucine and isoleucine degradation";"Pyruvate fermentation to butanol I";"Glutaryl-coa degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Aminobenzoate degradation";"beta-Alanine metabolism";"Phenylalanine metabolism" JAMg_model_10512.3 10 MetaCyc: PWY-8001;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-7559;MetaCyc: PWY-6842 "Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione metabolism";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II" JAMg_model_16208.3 5 Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;Reactome: R-HSA-163765;Reactome: R-HSA-9029558 "Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis" JAMg_model_4462.2 2 Reactome: R-HSA-2151201;Reactome: R-HSA-8964539 "Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism" JAMg_model_4438.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" JAMg_model_4198.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_12391.2 7 MetaCyc: PWY-6351;MetaCyc: PWY-7625;KEGG: 00564+2.7.8.11;Reactome: R-HSA-1483226;MetaCyc: PWY-6352;KEGG: 04070+2.7.8.11;KEGG: 00562+2.7.8.11 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Glycerophospholipid metabolism";"Synthesis of PI";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism" JAMg_model_11200.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" JAMg_model_4356.4 3 KEGG: 00510+2.4.1.265;Reactome: R-HSA-446193;Reactome: R-HSA-4724325 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)" JAMg_model_8838.1 5 MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5981;KEGG: 04070+2.7.7.41 "CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III";"Phosphatidylinositol signaling system" JAMg_model_11456.1 7 Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;MetaCyc: PWY-7511;Reactome: R-HSA-72163 "Neddylation";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Protein ubiquitination";"mRNA Splicing - Major Pathway" JAMg_model_6151.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" JAMg_model_20950.2 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" JAMg_model_12392.1 1 KEGG: 00970+6.1.1.20 "Aminoacyl-tRNA biosynthesis" JAMg_model_5406.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_5045.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_19514.1 4 Reactome: R-HSA-8964539;KEGG: 00332+1.2.1.41;KEGG: 00330+1.2.1.41;MetaCyc: PWY-6922 "Glutamate and glutamine metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis" JAMg_model_16921.1 56 Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-180585;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-68949 "CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vif-mediated degradation of APOBEC3G";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FCERI mediated NF-kB activation";"UCH proteinases";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of DVL";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"Orc1 removal from chromatin" JAMg_model_12705.3 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" JAMg_model_10755.1 4 MetaCyc: PWY-7807;Reactome: R-HSA-71737;MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1 "Glyphosate degradation III";"Pyrophosphate hydrolysis";"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation" JAMg_model_3398.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_16399.2 4 Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" JAMg_model_18654.1 10 KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-2206292;MetaCyc: PWY-6807;Reactome: R-HSA-2160916 "Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Other glycan degradation";"Neutrophil degranulation";"Galactose metabolism";"HS-GAG degradation";"MPS VII - Sly syndrome";"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation" JAMg_model_16855.1 1 Reactome: R-HSA-6798163 "Choline catabolism" JAMg_model_20624.1 3 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.25;Reactome: R-HSA-6798695 "Lysosomal oligosaccharide catabolism";"Other glycan degradation";"Neutrophil degranulation" JAMg_model_2644.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" JAMg_model_17966.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" JAMg_model_5574.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" JAMg_model_481.2 11 MetaCyc: PWY-6549;Reactome: R-HSA-71403;MetaCyc: PWY-5913;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6969;KEGG: 00720+1.1.1.42;MetaCyc: PWY-7254;MetaCyc: PWY-7124;KEGG: 00480+1.1.1.42;MetaCyc: PWY-6728;MetaCyc: PWY-7268 "L-glutamine biosynthesis III";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"Ethylene biosynthesis V (engineered)";"Glutathione metabolism";"Methylaspartate cycle";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" JAMg_model_10417.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" JAMg_model_1190.2 1 KEGG: 00230+4.6.1.2 "Purine metabolism" JAMg_model_1359.5 12 KEGG: 05163+2.7.11.1;Reactome: R-HSA-418885;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-193648;KEGG: 04714+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"DCC mediated attractive signaling";"Human immunodeficiency virus 1 infection";"G alpha (12/13) signalling events";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"G alpha (q) signalling events";"NRAGE signals death through JNK";"Thermogenesis";"Rho GTPase cycle";"Human papillomavirus infection" JAMg_model_1675.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" JAMg_model_3221.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism" JAMg_model_16997.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_20230.4 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" JAMg_model_2610.1 5 Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-6814122 "Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" JAMg_model_7037.1 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" JAMg_model_6263.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" JAMg_model_16444.2 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_13242.4 7 Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2 "Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism" JAMg_model_10797.7 1 Reactome: R-HSA-5676934 "Protein repair" JAMg_model_1821.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" JAMg_model_18910.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" JAMg_model_7588.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" JAMg_model_18324.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" JAMg_model_6599.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" JAMg_model_4015.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" JAMg_model_19162.2 1 Reactome: R-HSA-163560 "Triglyceride catabolism" JAMg_model_20984.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase" JAMg_model_10036.2 4 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.258;KEGG: 00513+2.4.1.258;Reactome: R-HSA-4720475 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Defective ALG3 causes ALG3-CDG (CDG-1d)" JAMg_model_19141.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" JAMg_model_14808.2 1 Reactome: R-HSA-525793 "Myogenesis" JAMg_model_9889.3 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" JAMg_model_4961.2 5 Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-182971 "InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation" JAMg_model_18250.1 57 Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-6798695;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783 "Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Neutrophil degranulation";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"FCERI mediated NF-kB activation";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Degradation of GLI2 by the proteasome" JAMg_model_1808.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" JAMg_model_650.8 4 KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202 "Glutathione metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines" JAMg_model_11532.1 20 KEGG: 05163+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-389357;KEGG: 05170+2.7.11.1;Reactome: R-HSA-8943724;Reactome: R-HSA-3371571;Reactome: R-HSA-5218920;Reactome: R-HSA-165159;Reactome: R-HSA-5674400;Reactome: R-HSA-380972;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-1257604;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-166208 "Human cytomegalovirus infection";"TP53 Regulates Metabolic Genes";"CD28 dependent PI3K/Akt signaling";"Human immunodeficiency virus 1 infection";"Regulation of PTEN gene transcription";"HSF1-dependent transactivation";"VEGFR2 mediated vascular permeability";"mTOR signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"Energy dependent regulation of mTOR by LKB1-AMPK";"Thermogenesis";"Regulation of TP53 Degradation";"PIP3 activates AKT signaling";"Amino acids regulate mTORC1";"Macroautophagy";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"mTORC1-mediated signalling" JAMg_model_14451.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" JAMg_model_5331.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" JAMg_model_14443.3 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" JAMg_model_7362.1 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_8984.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" JAMg_model_1151.5 1 Reactome: R-HSA-8950505 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" JAMg_model_13363.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_19454.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_10818.2 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_17128.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-5080 "Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I" JAMg_model_8900.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-71403 "Mitochondrial protein import";"Citric acid cycle (TCA cycle)" JAMg_model_20605.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" JAMg_model_2856.1 2 Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" JAMg_model_1622.1 31 MetaCyc: PWYG-321;MetaCyc: PWY-5367;MetaCyc: PWY-7746;MetaCyc: PWY-5994;Reactome: R-HSA-199220;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5366;MetaCyc: PWY-7388;MetaCyc: PWY-7723;MetaCyc: PWY-7663;MetaCyc: PWY-5971;MetaCyc: PWY-8047;MetaCyc: PWY-7858;MetaCyc: PWY-8049;Reactome: R-HSA-163765;MetaCyc: PWY-5142;MetaCyc: PWY-5989;MetaCyc: PWY-5147;Reactome: R-HSA-9029558;MetaCyc: PWY-5966-1;MetaCyc: PWY-7664;MetaCyc: PWY-5973;Reactome: R-HSA-75105;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6113;MetaCyc: PWY-6282;MetaCyc: PWY-4381;Reactome: R-HSA-2426168;MetaCyc: PWY-6519;MetaCyc: PWY-8012;MetaCyc: PWY-6799 "";"Petroselinate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"Fatty acid biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Bacterial bioluminescence";"Gondoate biosynthesis (anaerobic)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Bryostatin biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Pederin biosynthesis";"ChREBP activates metabolic gene expression";"Acyl-[acyl-carrier protein] thioesterase pathway";"Stearate biosynthesis II (bacteria and plants)";"Oleate biosynthesis I (plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Oleate biosynthesis IV (anaerobic)";"Cis-vaccenate biosynthesis";"Fatty acyl-CoA biosynthesis";"Biotin metabolism";"Superpathway of mycolate biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"8-amino-7-oxononanoate biosynthesis I";"Mupirocin biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)" JAMg_model_8702.6 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" JAMg_model_1290.2 56 Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785 "Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome" JAMg_model_12664.2 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" JAMg_model_16232.4 4 Reactome: R-HSA-156581;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;MetaCyc: PWY-5912 "Methylation";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis" JAMg_model_8876.1 1 Reactome: R-HSA-1632852 "Macroautophagy" JAMg_model_6600.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" JAMg_model_16393.3 4 KEGG: 00410+4.1.1.9;Reactome: R-HSA-9033241;Reactome: R-HSA-390247;KEGG: 00640+4.1.1.9 "beta-Alanine metabolism";"Peroxisomal protein import";"Beta-oxidation of very long chain fatty acids";"Propanoate metabolism" JAMg_model_13528.2 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" JAMg_model_17316.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_15812.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" JAMg_model_3851.1 1 Reactome: R-HSA-376172 "DSCAM interactions" JAMg_model_1770.4 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" JAMg_model_4160.4 4 Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825 "Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis" JAMg_model_15760.1 33 Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"ISG15 antiviral mechanism";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids" JAMg_model_14776.1 2 Reactome: R-HSA-909733;Reactome: R-HSA-8983711 "Interferon alpha/beta signaling";"OAS antiviral response" JAMg_model_5785.1 7 Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-6798695 "BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Neutrophil degranulation" JAMg_model_6932.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" JAMg_model_17488.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" JAMg_model_8361.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" JAMg_model_1546.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" JAMg_model_17322.2 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" JAMg_model_10134.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" JAMg_model_14363.1 2 Reactome: R-HSA-210745;Reactome: R-HSA-383280 "Regulation of gene expression in beta cells";"Nuclear Receptor transcription pathway" JAMg_model_2030.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" JAMg_model_4485.6 4 Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437;Reactome: R-HSA-5689603 "HATs acetylate histones";"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases" JAMg_model_9631.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" JAMg_model_15208.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" JAMg_model_997.5 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" JAMg_model_13036.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" JAMg_model_11098.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_8131.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" JAMg_model_21161.6 7 Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270 "AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" JAMg_model_18624.4 13 Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" JAMg_model_2848.3 12 KEGG: 00720+6.2.1.5;MetaCyc: PWY-5537;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-6969;MetaCyc: PWY-5913;MetaCyc: PWY-6728;MetaCyc: PWY-7384;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5538 "Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate VI" JAMg_model_15421.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" JAMg_model_5882.1 26 Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-389960;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-9609736 "RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"Aggrephagy";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"Formation of tubulin folding intermediates by CCT/TriC";"Mitotic Prometaphase";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors" JAMg_model_1192.2 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" JAMg_model_19843.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_8910.10 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" JAMg_model_5088.7 16 MetaCyc: PWY-5484;MetaCyc: PWY-6886;MetaCyc: PWY-1622;MetaCyc: PWY-8004;Reactome: R-HSA-70263;MetaCyc: PWY-5723;Reactome: R-HSA-70171;MetaCyc: PWY-7003;KEGG: 00680+4.2.1.11;MetaCyc: PWY-6901;MetaCyc: PWY-1042;MetaCyc: PWY-7218;MetaCyc: PWY-7124;MetaCyc: PWY-2221;MetaCyc: PWY-6142;KEGG: 00010+4.2.1.11 "Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Gluconeogenesis";"Rubisco shunt";"Glycolysis";"Glycerol degradation to butanol";"Methane metabolism";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Ethylene biosynthesis V (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis" JAMg_model_19799.2 5 Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" JAMg_model_182.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" JAMg_model_13756.2 7 Reactome: R-HSA-212436;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-381340;Reactome: R-HSA-2173796;Reactome: R-HSA-2644606;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"PPARA activates gene expression" JAMg_model_9293.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" JAMg_model_4298.1 8 MetaCyc: PWY-8086;KEGG: 00620+1.1.1.27;KEGG: 00010+1.1.1.27;Reactome: R-HSA-70268;MetaCyc: PWY-5481;KEGG: 00270+1.1.1.27;MetaCyc: PWY-6901;KEGG: 00640+1.1.1.27 "(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate";"Cysteine and methionine metabolism";"Superpathway of glucose and xylose degradation";"Propanoate metabolism" JAMg_model_21055.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" JAMg_model_4808.5 2 Reactome: R-HSA-5689880;Reactome: R-HSA-8949215 "Ub-specific processing proteases";"Mitochondrial calcium ion transport" JAMg_model_138.2 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" JAMg_model_11685.4 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" JAMg_model_14468.1 18 MetaCyc: PWY-7417;MetaCyc: PWY-7416;Reactome: R-HSA-1482925;Reactome: R-HSA-1482922;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482839;Reactome: R-HSA-1482801;MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783 "Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG";"Acyl chain remodelling of PI";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Synthesis of PA";"Acyl chain remodelling of PE";"Acyl chain remodelling of PS";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Plasmalogen degradation" JAMg_model_10807.3 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_15933.1 1 KEGG: 00270+2.1.1.37 "Cysteine and methionine metabolism" JAMg_model_14261.3 3 KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757;MetaCyc: PWY-2161 "Folate biosynthesis";"Metabolism of folate and pterines";"Folate polyglutamylation" JAMg_model_2002.2 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" JAMg_model_14338.6 5 KEGG: 00531+3.1.6.14;Reactome: R-HSA-432720;Reactome: R-HSA-6798695;Reactome: R-HSA-2022857;Reactome: R-HSA-2206305 "Glycosaminoglycan degradation";"Lysosome Vesicle Biogenesis";"Neutrophil degranulation";"Keratan sulfate degradation";"MPS IIID - Sanfilippo syndrome D" JAMg_model_4758.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_2347.1 3 Reactome: R-HSA-429947;Reactome: R-HSA-5617472;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" JAMg_model_5924.1 3 Reactome: R-HSA-8951664;MetaCyc: PWY-7511;Reactome: R-HSA-349425 "Neddylation";"Protein ubiquitination";"Autodegradation of the E3 ubiquitin ligase COP1" JAMg_model_5874.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_13326.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" JAMg_model_583.6 1 Reactome: R-HSA-71384 "Ethanol oxidation" JAMg_model_9047.3 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_16589.3 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" JAMg_model_10135.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394 "Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER" JAMg_model_8175.1 1 Reactome: R-HSA-9616222 "Transcriptional regulation of granulopoiesis" JAMg_model_8885.6 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" JAMg_model_8992.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_10975.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" JAMg_model_7836.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_20857.3 14 MetaCyc: PWY-5078;MetaCyc: PWY-5104;MetaCyc: PWY-7767;KEGG: 00290+2.6.1.42;Reactome: R-HSA-70895;KEGG: 00280+2.6.1.42;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5057;MetaCyc: PWY-5076;MetaCyc: PWY-5108;MetaCyc: PWY-5101;KEGG: 00270+2.6.1.42;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5103 "L-isoleucine degradation II";"L-isoleucine biosynthesis IV";"L-leucine degradation IV (Stickland reaction)";"Valine, leucine and isoleucine biosynthesis";"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation";"Pantothenate and CoA biosynthesis";"L-valine degradation II";"L-leucine degradation III";"L-isoleucine biosynthesis V";"L-isoleucine biosynthesis II";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis";"L-isoleucine biosynthesis III" JAMg_model_4930.2 6 Reactome: R-HSA-163210;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1268020;MetaCyc: PWY-7980;Reactome: R-HSA-8949613;KEGG: 00195+7.1.2.2 "Formation of ATP by chemiosmotic coupling";"Oxidative phosphorylation";"Mitochondrial protein import";"ATP biosynthesis";"Cristae formation";"Photosynthesis" JAMg_model_21104.1 57 Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-6798695 "Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"UCH proteinases";"FCERI mediated NF-kB activation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"Neutrophil degranulation" JAMg_model_13397.6 7 MetaCyc: PWY-3385;MetaCyc: PWY-7782;Reactome: R-HSA-1483191;MetaCyc: PWY-7886;Reactome: R-HSA-1483213;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7818 "Choline biosynthesis I";"Plasmalogen biosynthesis";"Synthesis of PC";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PE";"Glycerophospholipid metabolism";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)" JAMg_model_5302.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_3963.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" JAMg_model_16858.3 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" JAMg_model_2592.2 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_14765.3 3 Reactome: R-HSA-4419969;Reactome: R-HSA-2995383;Reactome: R-HSA-2980766 "Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown" JAMg_model_13790.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706 "Peptide chain elongation";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit" JAMg_model_16856.1 1 Reactome: R-HSA-6798163 "Choline catabolism" JAMg_model_11704.4 7 Reactome: R-HSA-73817;KEGG: 00250+2.4.2.14;MetaCyc: PWY-7282;MetaCyc: PWY-6121;MetaCyc: PWY-6122;MetaCyc: PWY-6277;KEGG: 00230+2.4.2.14 "Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism" JAMg_model_13255.2 7 Reactome: R-HSA-1221632;Reactome: R-HSA-110328;Reactome: R-HSA-2559586;Reactome: R-HSA-110329;Reactome: R-HSA-110331;Reactome: R-HSA-171306;Reactome: R-HSA-110330 "Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine";"Packaging Of Telomere Ends";"Recognition and association of DNA glycosylase with site containing an affected purine" JAMg_model_1364.3 1 Reactome: R-HSA-1483101 "Synthesis of PS" JAMg_model_13068.3 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" JAMg_model_15725.2 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" JAMg_model_16050.1 6 MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085;MetaCyc: PWY-5067;MetaCyc: PWY-622 "Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis" JAMg_model_10246.1 13 Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2024101;Reactome: R-HSA-2022857 "Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"CS/DS degradation";"Keratan sulfate degradation" JAMg_model_8834.2 10 Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-76042;MetaCyc: PWY-7511;Reactome: R-HSA-73779;Reactome: R-HSA-75953 "HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Protein ubiquitination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation" JAMg_model_1970.3 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_15419.2 5 Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-174490 "Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"HCMV Late Events";"Membrane binding and targetting of GAG proteins" JAMg_model_4428.1 27 Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-159236 "Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript" JAMg_model_7739.3 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" JAMg_model_8698.2 22 MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7592;MetaCyc: PWY-7728;MetaCyc: PWY-7619;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7053;KEGG: 00062+4.2.1.134;MetaCyc: PWY-5080;MetaCyc: PWY-7049;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7727;MetaCyc: PWY-5353;MetaCyc: PWY-7035;MetaCyc: PWY-7726;MetaCyc: PWY-7606;MetaCyc: PWY-6958 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)" JAMg_model_17269.6 3 MetaCyc: PWY-8106;Reactome: R-HSA-6782315;MetaCyc: PWY-6700 "Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)" JAMg_model_11252.9 9 KEGG: 00564+1.1.1.94;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-7385;MetaCyc: PWY-7902;MetaCyc: PWY-5667;MetaCyc: PWY-6118;MetaCyc: PWY-5981 "Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"1,3-propanediol biosynthesis (engineered)";"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis III" JAMg_model_9901.1 29 Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-73863;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-5696400;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-427413;Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-5696395;Reactome: R-HSA-6796648;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-75953 "Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"Dual Incision in GG-NER";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of Incision Complex in GG-NER";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation" JAMg_model_14759.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5620912 "Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane" JAMg_model_7774.2 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" JAMg_model_2777.4 14 Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-426486;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-203927 "Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Small interfering RNA (siRNA) biogenesis";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"MicroRNA (miRNA) biogenesis" JAMg_model_10622.2 7 Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518 "Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2" JAMg_model_17345.2 27 Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-159231;Reactome: R-HSA-3301854 "ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly" JAMg_model_7521.4 2 Reactome: R-HSA-2564830;Reactome: R-HSA-5693554 "Cytosolic iron-sulfur cluster assembly";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" JAMg_model_7201.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_1629.2 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" JAMg_model_577.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_5028.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_10689.3 6 Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450385 "KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" JAMg_model_7728.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" JAMg_model_7423.2 1 Reactome: R-HSA-6799198 "Complex I biogenesis" JAMg_model_5587.6 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" JAMg_model_14104.2 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" JAMg_model_14412.1 10 MetaCyc: PWY-1861;KEGG: 00680+2.7.1.11;KEGG: 00051+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00030+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00052+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-1042 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Methane metabolism";"Fructose and mannose metabolism";"Glycolysis";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)" JAMg_model_10875.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis" JAMg_model_9488.2 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" JAMg_model_135.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" JAMg_model_17775.3 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" JAMg_model_12974.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_10003.1 9 KEGG: 04070+3.1.4.11;Reactome: R-HSA-112043;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;Reactome: R-HSA-416476;MetaCyc: PWY-6351;MetaCyc: PWY-8052 "Phosphatidylinositol signaling system";"PLC beta mediated events";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis" JAMg_model_10808.1 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_14279.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" JAMg_model_8701.3 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" JAMg_model_8653.2 3 Reactome: R-HSA-6787639;Reactome: R-HSA-727802;Reactome: R-HSA-5619078 "GDP-fucose biosynthesis";"Transport of nucleotide sugars";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)" JAMg_model_19.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" JAMg_model_5904.2 16 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-9633012 "Peptide chain elongation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" JAMg_model_18046.1 5 Reactome: R-HSA-532668;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-901042;Reactome: R-HSA-879415 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Calnexin/calreticulin cycle";"Advanced glycosylation endproduct receptor signaling" JAMg_model_3411.5 1 Reactome: R-HSA-977347 "Serine biosynthesis" JAMg_model_16638.1 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" JAMg_model_5692.1 7 KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection" JAMg_model_4970.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" JAMg_model_13154.1 1 Reactome: R-HSA-912446 "Meiotic recombination" JAMg_model_8153.8 3 KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3 "Methane metabolism";"Serine biosynthesis";"Glycine, serine and threonine metabolism" JAMg_model_3009.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" JAMg_model_3198.6 1 Reactome: R-HSA-1483191 "Synthesis of PC" JAMg_model_3303.6 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" JAMg_model_7597.2 8 Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68827 "E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex" JAMg_model_7624.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_3755.1 2 Reactome: R-HSA-5601884;Reactome: R-HSA-1221632 "PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis" JAMg_model_7975.1 6 Reactome: R-HSA-3299685;MetaCyc: PWY-6854;Reactome: R-HSA-9615017;Reactome: R-HSA-8950505;Reactome: R-HSA-2151201;Reactome: R-HSA-8862803 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Transcriptional activation of mitochondrial biogenesis";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" JAMg_model_20052.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" JAMg_model_10979.1 5 Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-5694530 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER" JAMg_model_5977.1 3 Reactome: R-HSA-948021;Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Transport to the Golgi and subsequent modification";"Cargo concentration in the ER";"COPII-mediated vesicle transport" JAMg_model_2272.1 3 Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" JAMg_model_20243.1 5 Reactome: R-HSA-3656253;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;MetaCyc: PWY-6558 "Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Heparan sulfate biosynthesis (late stages)" JAMg_model_12391.4 7 MetaCyc: PWY-7625;MetaCyc: PWY-6351;KEGG: 04070+2.7.8.11;KEGG: 00562+2.7.8.11;MetaCyc: PWY-6352;Reactome: R-HSA-1483226;KEGG: 00564+2.7.8.11 "Phosphatidylinositol biosynthesis II (eukaryotes)";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"Synthesis of PI";"Glycerophospholipid metabolism" JAMg_model_9427.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" JAMg_model_8435.4 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_21295.1 7 MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-7445 "Matairesinol biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation" JAMg_model_18090.5 3 Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" JAMg_model_12835.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" JAMg_model_216.3 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" JAMg_model_21137.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" JAMg_model_7197.1 2 KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23 "Pyrimidine metabolism";"Drug metabolism - other enzymes" JAMg_model_7587.2 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" JAMg_model_1675.2 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_8550.5 14 MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-5080 "Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I" JAMg_model_19141.3 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" JAMg_model_10279.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_3000.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" JAMg_model_3217.3 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_17485.1 4 KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3 "Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism" JAMg_model_16083.2 3 MetaCyc: PWY-7799;Reactome: R-HSA-2514859;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Inactivation, recovery and regulation of the phototransduction cascade";"Ac/N-end rule pathway" JAMg_model_20873.4 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_20729.1 1 KEGG: 00270+2.1.1.37 "Cysteine and methionine metabolism" JAMg_model_14466.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" JAMg_model_21122.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" JAMg_model_10247.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" JAMg_model_19289.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9615710 "Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy" JAMg_model_15870.4 8 KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1 "Galactose metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Glycolysis";"Amino sugar and nucleotide sugar metabolism" JAMg_model_2506.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" JAMg_model_10128.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_9627.1 1 Reactome: R-HSA-6798163 "Choline catabolism" JAMg_model_16609.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" JAMg_model_16624.3 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" JAMg_model_16194.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" JAMg_model_20782.2 57 Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-69481 "Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"G2/M Checkpoints" JAMg_model_2114.1 3 Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14 "Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis" JAMg_model_9954.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" JAMg_model_13437.1 57 Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-382556 "Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"ABC-family proteins mediated transport" JAMg_model_11412.1 1 Reactome: R-HSA-400253 "Circadian Clock" JAMg_model_19561.1 3 MetaCyc: PWY-7831;Reactome: R-HSA-9033807;MetaCyc: PWY-7833 "ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)" JAMg_model_4220.2 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" JAMg_model_12337.2 26 Reactome: R-HSA-210744;Reactome: R-HSA-933541;Reactome: R-HSA-201722;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-3899300;Reactome: R-HSA-1912408;Reactome: R-HSA-400253;Reactome: R-HSA-8866907;Reactome: R-HSA-2894862;Reactome: R-HSA-9614657;Reactome: R-HSA-2644606;Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-918233;Reactome: R-HSA-9018519;Reactome: R-HSA-9617629;Reactome: R-HSA-381340;Reactome: R-HSA-3214847;Reactome: R-HSA-2122947;Reactome: R-HSA-1368082;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-1989781;Reactome: R-HSA-5621575;Reactome: R-HSA-3134973 "Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"TRAF6 mediated IRF7 activation";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"SUMOylation of transcription cofactors";"Pre-NOTCH Transcription and Translation";"Circadian Clock";"Activation of the TFAP2 (AP-2) family of transcription factors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"FOXO-mediated transcription of cell death genes";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TRAF3-dependent IRF activation pathway";"Estrogen-dependent gene expression";"Regulation of FOXO transcriptional activity by acetylation";"Transcriptional regulation of white adipocyte differentiation";"HATs acetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"CD209 (DC-SIGN) signaling";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production" JAMg_model_14747.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" JAMg_model_17687.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" JAMg_model_7362.2 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_4272.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_10134.5 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" JAMg_model_1501.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" JAMg_model_174.2 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_1151.9 1 Reactome: R-HSA-8950505 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" JAMg_model_1523.10 2 Reactome: R-HSA-8949613;Reactome: R-HSA-1268020 "Cristae formation";"Mitochondrial protein import" JAMg_model_8875.4 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_2777.3 14 Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-426486;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-426496 "Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Small interfering RNA (siRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs" JAMg_model_17314.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_17195.2 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" JAMg_model_17785.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" JAMg_model_2567.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" JAMg_model_14221.1 14 MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7036 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II" JAMg_model_4149.1 6 KEGG: 00500+2.4.1.18;Reactome: R-HSA-3878781;MetaCyc: PWY-7900;MetaCyc: PWY-5067;MetaCyc: PWY-622;Reactome: R-HSA-3322077 "Starch and sucrose metabolism";"Glycogen storage disease type IV (GBE1)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis";"Glycogen synthesis" JAMg_model_12444.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" JAMg_model_14676.2 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" JAMg_model_10404.1 13 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-416476;Reactome: R-HSA-5687128;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-3928662;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Rho GTPase cycle";"Human papillomavirus infection";"Relaxin signaling pathway";"NRAGE signals death through JNK";"G alpha (q) signalling events";"MAPK6/MAPK4 signaling";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"EPHB-mediated forward signaling";"Human immunodeficiency virus 1 infection" JAMg_model_423.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" JAMg_model_16046.1 6 Reactome: R-HSA-5358606;Reactome: R-HSA-5632968;Reactome: R-HSA-5632928;Reactome: R-HSA-6796648;Reactome: R-HSA-5632927;Reactome: R-HSA-5358565 "Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH3";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)" JAMg_model_6793.1 6 Reactome: R-HSA-199220;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-75105;Reactome: R-HSA-9640463;Reactome: R-HSA-9029558 "Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis";"Wax biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis" JAMg_model_6525.2 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" JAMg_model_12414.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" JAMg_model_15766.2 17 Reactome: R-HSA-69166;Reactome: R-HSA-6782210;Reactome: R-HSA-174417;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-69183;Reactome: R-HSA-174437;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-174414;Reactome: R-HSA-110314 "Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand (Lagging Strand) Synthesis";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate from the C-strand";"Polymerase switching";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Processive synthesis on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex" JAMg_model_14117.1 3 Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596 "Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I" JAMg_model_17401.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" JAMg_model_12165.1 26 Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-9648025;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-389960;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-389977 "Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"Formation of tubulin folding intermediates by CCT/TriC";"Mitotic Prometaphase";"HCMV Early Events";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway" JAMg_model_10599.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" JAMg_model_4219.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" JAMg_model_14627.1 20 MetaCyc: PWY-7726;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7337;Reactome: R-HSA-9033241;MetaCyc: PWY-5136;MetaCyc: PWY-6920;MetaCyc: PWY-7340;MetaCyc: PWY-735;MetaCyc: PWY-7854;MetaCyc: PWY-7291;MetaCyc: PWY-7338;MetaCyc: PWY-7288;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858;KEGG: 00592+1.3.3.6 "(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Peroxisomal protein import";"Fatty acid beta-oxidation II (plant peroxisome)";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II";"alpha-Linolenic acid metabolism" JAMg_model_18125.1 9 KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52 "Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis" JAMg_model_13226.3 3 KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I" JAMg_model_12460.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" JAMg_model_19550.2 56 Reactome: R-HSA-180585;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-180534 "Vif-mediated degradation of APOBEC3G";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FCERI mediated NF-kB activation";"UCH proteinases";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Interleukin-1 signaling";"ABC-family proteins mediated transport";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4" JAMg_model_5287.4 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" JAMg_model_7510.3 3 KEGG: 00510+2.4.1.144;Reactome: R-HSA-975574;MetaCyc: PWY-7426 "N-Glycan biosynthesis";"Reactions specific to the hybrid N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)" JAMg_model_9184.1 6 KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817 "Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)" JAMg_model_1294.1 56 Reactome: R-HSA-180585;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-350562;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-180534 "Vif-mediated degradation of APOBEC3G";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FCERI mediated NF-kB activation";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"Orc1 removal from chromatin";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Regulation of ornithine decarboxylase (ODC)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4" JAMg_model_18889.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" JAMg_model_10622.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320 "AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes" JAMg_model_17233.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" JAMg_model_1563.1 1 Reactome: R-HSA-5624958 "ARL13B-mediated ciliary trafficking of INPP5E" JAMg_model_18117.3 12 KEGG: 00450+4.4.1.13;MetaCyc: PWY-6309;KEGG: 00380+2.6.1.7;MetaCyc: PWY-601;MetaCyc: PWY-1187;MetaCyc: PWY-6936;KEGG: 00270+4.4.1.13;MetaCyc: PWY-6842;MetaCyc: PWY-801;MetaCyc: PWY-7901;Reactome: R-HSA-71240;MetaCyc: PWY-2821 "Selenocompound metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"Glucosinolate biosynthesis from tryptophan";"Glucosinolate biosynthesis from homomethionine";"Seleno-amino acid biosynthesis (plants)";"Cysteine and methionine metabolism";"Glutathione-mediated detoxification II";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from tyrosine";"Tryptophan catabolism";"Glucosinolate biosynthesis from phenylalanine" JAMg_model_17309.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" JAMg_model_6316.1 3 Reactome: R-HSA-110314;Reactome: R-HSA-5689880;Reactome: R-HSA-6783310 "Recognition of DNA damage by PCNA-containing replication complex";"Ub-specific processing proteases";"Fanconi Anemia Pathway" JAMg_model_9642.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_9241.2 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" JAMg_model_18325.3 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" JAMg_model_13588.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_21184.2 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" JAMg_model_9797.2 14 Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-191273;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012 "L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Cholesterol biosynthesis";"Viral mRNA Translation";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency" JAMg_model_6758.1 7 Reactome: R-HSA-389661;KEGG: 00020+2.3.1.61;Reactome: R-HSA-71064;Reactome: R-HSA-71403;MetaCyc: PWY-5084;KEGG: 00380+2.3.1.61;KEGG: 00310+2.3.1.61 "Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine catabolism";"Citric acid cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Lysine degradation" JAMg_model_20443.1 5 Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043 "Glutathione synthesis and recycling";"Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis" JAMg_model_8476.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" JAMg_model_15202.1 10 Reactome: R-HSA-8934903;Reactome: R-HSA-6814122;Reactome: R-HSA-6798695;Reactome: R-HSA-201688;Reactome: R-HSA-6804756;Reactome: R-HSA-2514853;Reactome: R-HSA-8948751;Reactome: R-HSA-8939243;Reactome: R-HSA-1483191;Reactome: R-HSA-445144 "Receptor Mediated Mitophagy";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation";"WNT mediated activation of DVL";"Regulation of TP53 Activity through Phosphorylation";"Condensation of Prometaphase Chromosomes";"Regulation of PTEN stability and activity";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Synthesis of PC";"Signal transduction by L1" JAMg_model_9576.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_860.3 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" JAMg_model_6807.4 5 KEGG: 00630+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00720+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33 "Glyoxylate and dicarboxylate metabolism";"Iron uptake and transport";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis" JAMg_model_7190.6 12 Reactome: R-HSA-416482;KEGG: 05170+2.7.11.1;Reactome: R-HSA-418885;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-193648;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1 "G alpha (12/13) signalling events";"Human immunodeficiency virus 1 infection";"DCC mediated attractive signaling";"Human cytomegalovirus infection";"Human papillomavirus infection";"Rho GTPase cycle";"Thermogenesis";"Relaxin signaling pathway";"G alpha (q) signalling events";"NRAGE signals death through JNK";"mTOR signaling pathway";"PI3K-Akt signaling pathway" JAMg_model_16383.1 1 Reactome: R-HSA-6798163 "Choline catabolism" JAMg_model_496.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" JAMg_model_1040.2 1 Reactome: R-HSA-5620924 "Intraflagellar transport" JAMg_model_12948.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" JAMg_model_12688.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_20984.2 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-5576893 "Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Phase 2 - plateau phase" JAMg_model_3822.1 4 Reactome: R-HSA-5693607;Reactome: R-HSA-111465;Reactome: R-HSA-5689880;Reactome: R-HSA-176187 "Processing of DNA double-strand break ends";"Apoptotic cleavage of cellular proteins";"Ub-specific processing proteases";"Activation of ATR in response to replication stress" JAMg_model_4300.1 8 KEGG: 00270+1.1.1.27;KEGG: 00640+1.1.1.27;MetaCyc: PWY-6901;KEGG: 00010+1.1.1.27;Reactome: R-HSA-70268;MetaCyc: PWY-8086;KEGG: 00620+1.1.1.27;MetaCyc: PWY-5481 "Cysteine and methionine metabolism";"Propanoate metabolism";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate" JAMg_model_19866.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_16062.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" JAMg_model_8213.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_13410.1 4 MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49;KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268 "Entner-Doudoroff pathway I";"Pentose phosphate pathway";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" JAMg_model_10021.4 4 KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841;KEGG: 00053+1.13.99.1;Reactome: R-HSA-1855183 "Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Ascorbate and aldarate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol" JAMg_model_1102.2 2 KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859 "Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade" JAMg_model_20331.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" JAMg_model_3303.2 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" JAMg_model_12391.1 7 KEGG: 00564+2.7.8.11;Reactome: R-HSA-1483226;MetaCyc: PWY-6352;KEGG: 04070+2.7.8.11;KEGG: 00562+2.7.8.11;MetaCyc: PWY-6351;MetaCyc: PWY-7625 "Glycerophospholipid metabolism";"Synthesis of PI";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol biosynthesis II (eukaryotes)" JAMg_model_1040.4 1 Reactome: R-HSA-5620924 "Intraflagellar transport" JAMg_model_19428.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-429958 "Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease" JAMg_model_9246.1 2 Reactome: R-HSA-425397;Reactome: R-HSA-5619061 "Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)" JAMg_model_16984.2 14 Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-110312;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121 "Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Polymerase switching";"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI" JAMg_model_14184.4 3 MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106 "Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)" JAMg_model_10992.4 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" JAMg_model_7037.3 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" JAMg_model_15100.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_3075.1 52 Reactome: R-HSA-76071;Reactome: R-HSA-75953;Reactome: R-HSA-167242;Reactome: R-HSA-76066;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-73762;Reactome: R-HSA-73980;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-6782135;Reactome: R-HSA-5250924;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-72203;Reactome: R-HSA-5601884;Reactome: R-HSA-6803529;Reactome: R-HSA-76042;Reactome: R-HSA-1834949;Reactome: R-HSA-9018519;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-76061;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-203927;Reactome: R-HSA-73780;Reactome: R-HSA-5578749;Reactome: R-HSA-72163;Reactome: R-HSA-749476;Reactome: R-HSA-167160;Reactome: R-HSA-427413;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-168325;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-6781823;Reactome: R-HSA-73863;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-5617472;Reactome: R-HSA-77075 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"Dual incision in TC-NER";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Capped Intron-Containing Pre-mRNA";"PIWI-interacting RNA (piRNA) biogenesis";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Cytosolic sensors of pathogen-associated DNA";"Estrogen-dependent gene expression";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"MicroRNA (miRNA) biogenesis";"RNA Polymerase III Chain Elongation";"Transcriptional regulation by small RNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Viral Messenger RNA Synthesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Termination";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Pol II CTD phosphorylation and interaction with CE" JAMg_model_3937.1 24 Reactome: R-HSA-392517;Reactome: R-HSA-111931;Reactome: R-HSA-5687128;Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-4420097;Reactome: R-HSA-5610780;Reactome: R-HSA-983231;Reactome: R-HSA-5610783;Reactome: R-HSA-422356;KEGG: 04150+2.7.11.11;Reactome: R-HSA-5621575;Reactome: R-HSA-5610785;Reactome: R-HSA-163560;Reactome: R-HSA-8853659;Reactome: R-HSA-163358;Reactome: R-HSA-9634600;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-9010642;Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-8963896;Reactome: R-HSA-432040 "Rap1 signalling";"PKA-mediated phosphorylation of CREB";"MAPK6/MAPK4 signaling";"PKA activation";"DARPP-32 events";"VEGFA-VEGFR2 Pathway";"Degradation of GLI1 by the proteasome";"Factors involved in megakaryocyte development and platelet production";"Degradation of GLI2 by the proteasome";"Regulation of insulin secretion";"mTOR signaling pathway";"CD209 (DC-SIGN) signaling";"GLI3 is processed to GLI3R by the proteasome";"Triglyceride catabolism";"RET signaling";"PKA-mediated phosphorylation of key metabolic factors";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"ROBO receptors bind AKAP5";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"HDL assembly";"Vasopressin regulates renal water homeostasis via Aquaporins" JAMg_model_9755.4 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" JAMg_model_10824.2 12 KEGG: 00230+2.7.1.25;KEGG: 00920+2.7.7.4;MetaCyc: PWY-5278;Reactome: R-HSA-174362;Reactome: R-HSA-2408550;KEGG: 00450+2.7.7.4;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5340;MetaCyc: PWY-6683;KEGG: 00230+2.7.7.4;KEGG: 00920+2.7.1.25;MetaCyc: PWY-6932 "Purine metabolism";"Sulfur metabolism";"Sulfite oxidation III";"Transport and synthesis of PAPS";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Selenocompound metabolism";"Monobactam biosynthesis";"Sulfate activation for sulfonation";"Assimilatory sulfate reduction III";"Purine metabolism";"Sulfur metabolism";"Selenate reduction" JAMg_model_314.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" JAMg_model_4975.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_7552.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" JAMg_model_17534.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_7597.3 8 Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68689 "Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex" JAMg_model_14736.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_18866.1 3 Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" JAMg_model_359.2 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" JAMg_model_12121.1 6 Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6952;Reactome: R-HSA-163560;MetaCyc: PWY-4261;MetaCyc: PWY-6118 "Synthesis of PA";"Glycerophospholipid metabolism";"Glycerophosphodiester degradation";"Triglyceride catabolism";"Glycerol degradation I";"Glycerol-3-phosphate shuttle" JAMg_model_13627.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-6798695 "SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation" JAMg_model_13339.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" JAMg_model_10863.1 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_15154.1 1 KEGG: 00051+4.2.1.68 "Fructose and mannose metabolism" JAMg_model_19296.3 3 Reactome: R-HSA-191859;Reactome: R-HSA-6804760;Reactome: R-HSA-3214858 "snRNP Assembly";"Regulation of TP53 Activity through Methylation";"RMTs methylate histone arginines" JAMg_model_3755.2 2 Reactome: R-HSA-5601884;Reactome: R-HSA-1221632 "PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis" JAMg_model_12110.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" JAMg_model_2764.7 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" JAMg_model_19931.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_4323.1 14 MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-8051;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4 "Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Retinoid metabolism and transport";"Anandamide biosynthesis I";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Anandamide biosynthesis II";"Linoleic acid metabolism" JAMg_model_12281.3 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" JAMg_model_21356.2 9 Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167161 "RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation" JAMg_model_12337.6 26 Reactome: R-HSA-201722;Reactome: R-HSA-933541;Reactome: R-HSA-210744;Reactome: R-HSA-1912408;Reactome: R-HSA-3899300;Reactome: R-HSA-8941856;Reactome: R-HSA-1234158;Reactome: R-HSA-8866907;Reactome: R-HSA-2894862;Reactome: R-HSA-400253;Reactome: R-HSA-9018519;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-2644606;Reactome: R-HSA-9614657;Reactome: R-HSA-9617629;Reactome: R-HSA-381340;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-9013695;Reactome: R-HSA-1368082;Reactome: R-HSA-2122947;Reactome: R-HSA-5621575;Reactome: R-HSA-3134973;Reactome: R-HSA-1989781 "Formation of the beta-catenin:TCF transactivating complex";"TRAF6 mediated IRF7 activation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Pre-NOTCH Transcription and Translation";"SUMOylation of transcription cofactors";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"Activation of the TFAP2 (AP-2) family of transcription factors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Circadian Clock";"Estrogen-dependent gene expression";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"FOXO-mediated transcription of cell death genes";"Regulation of FOXO transcriptional activity by acetylation";"Transcriptional regulation of white adipocyte differentiation";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"PPARA activates gene expression" JAMg_model_16385.1 1 Reactome: R-HSA-6798163 "Choline catabolism" JAMg_model_14542.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72706 "Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit" JAMg_model_19131.5 14 MetaCyc: PWY-8052;MetaCyc: PWY-6453;MetaCyc: PWY-8055;KEGG: 00564+3.1.3.4;Reactome: R-HSA-1483213;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8051;KEGG: 00565+3.1.3.4;Reactome: R-HSA-75109;Reactome: R-HSA-4419969;KEGG: 00600+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-8053;Reactome: R-HSA-1483191 "2-arachidonoylglycerol biosynthesis";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PE";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Ether lipid metabolism";"Triglyceride biosynthesis";"Depolymerisation of the Nuclear Lamina";"Sphingolipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Synthesis of PC" JAMg_model_8384.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878 "MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport" JAMg_model_7117.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" JAMg_model_980.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" JAMg_model_4814.2 13 Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72764 "L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination" JAMg_model_4336.3 34 Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-4551638;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-9639288;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-168271 "ISG15 antiviral mechanism";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"SUMOylation of chromatin organization proteins";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Mitotic Prometaphase";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Amino acids regulate mTORC1";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus" JAMg_model_10814.1 9 KEGG: 00720+6.4.1.1;Reactome: R-HSA-196780;Reactome: R-HSA-70263;KEGG: 00620+6.4.1.1;MetaCyc: PWY-6146;MetaCyc: PWY-8086;MetaCyc: PWY-6142;Reactome: R-HSA-3371599;KEGG: 00020+6.4.1.1 "Carbon fixation pathways in prokaryotes";"Biotin transport and metabolism";"Gluconeogenesis";"Pyruvate metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Defective HLCS causes multiple carboxylase deficiency";"Citrate cycle (TCA cycle)" JAMg_model_7409.1 3 Reactome: R-HSA-77588;Reactome: R-HSA-111367;Reactome: R-HSA-73856 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination" JAMg_model_7717.1 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_2956.1 3 Reactome: R-HSA-6782315;MetaCyc: PWY-6829;MetaCyc: PWY-7888 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)" JAMg_model_13508.1 3 Reactome: R-HSA-2022854;Reactome: R-HSA-913709;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"O-linked glycosylation of mucins";"N-Glycan antennae elongation" JAMg_model_6941.3 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" JAMg_model_5587.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" JAMg_model_18194.2 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_561.3 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_12036.1 1 KEGG: 00970+6.1.1.19 "Aminoacyl-tRNA biosynthesis" JAMg_model_21009.1 26 Reactome: R-HSA-8939256;Reactome: R-HSA-8939247;Reactome: R-HSA-8939236;Reactome: R-HSA-8939242;Reactome: R-HSA-8940973;Reactome: R-HSA-9018519;Reactome: R-HSA-8941284;Reactome: R-HSA-8931987;Reactome: R-HSA-8949275;Reactome: R-HSA-8939243;Reactome: R-HSA-8936459;Reactome: R-HSA-8878166;Reactome: R-HSA-8877330;Reactome: R-HSA-8939246;Reactome: R-HSA-8939245;Reactome: R-HSA-8934593;Reactome: R-HSA-8941332;Reactome: R-HSA-432047;Reactome: R-HSA-8951936;Reactome: R-HSA-8935964;Reactome: R-HSA-8951911;Reactome: R-HSA-8939902;Reactome: R-HSA-8941326;Reactome: R-HSA-9616222;Reactome: R-HSA-8941333;Reactome: R-HSA-8941858 "RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX2 regulates osteoblast differentiation";"Estrogen-dependent gene expression";"RUNX2 regulates chondrocyte maturation";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional regulation by RUNX2";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX1 regulates transcription of genes involved in BCR signaling";"Regulation of RUNX1 Expression and Activity";"RUNX2 regulates genes involved in cell migration";"Passive transport by Aquaporins";"RUNX3 regulates p14-ARF";"RUNX1 regulates expression of components of tight junctions";"RUNX3 regulates RUNX1-mediated transcription";"Regulation of RUNX2 expression and activity";"RUNX2 regulates bone development";"Transcriptional regulation of granulopoiesis";"RUNX2 regulates genes involved in differentiation of myeloid cells";"Regulation of RUNX3 expression and activity" JAMg_model_639.1 24 Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-983189 "MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"Mitotic Prometaphase";"HCMV Early Events";"Kinesins" JAMg_model_13649.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" JAMg_model_1477.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427 "Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains" JAMg_model_12219.1 5 Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-5693565 "G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" JAMg_model_6550.2 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" JAMg_model_20862.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" JAMg_model_20230.2 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" JAMg_model_1100.1 4 Reactome: R-HSA-446203;Reactome: R-HSA-1799339;Reactome: R-HSA-879415;Reactome: R-HSA-6798695 "Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane";"Advanced glycosylation endproduct receptor signaling";"Neutrophil degranulation" JAMg_model_939.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" JAMg_model_18983.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450385 "KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" JAMg_model_308.1 2 Reactome: R-HSA-1660661;Reactome: R-HSA-6798695 "Sphingolipid de novo biosynthesis";"Neutrophil degranulation" JAMg_model_2886.1 10 KEGG: 00562+2.7.1.153;KEGG: 04150+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 04070+2.7.1.153;KEGG: 04151+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 05170+2.7.1.153;MetaCyc: PWY-6352;KEGG: 05165+2.7.1.153;KEGG: 05163+2.7.1.153 "Inositol phosphate metabolism";"mTOR signaling pathway";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Phosphatidylinositol signaling system";"PI3K-Akt signaling pathway";"Synthesis of PIPs at the plasma membrane";"Human immunodeficiency virus 1 infection";"3-phosphoinositide biosynthesis";"Human papillomavirus infection";"Human cytomegalovirus infection" JAMg_model_14821.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" JAMg_model_16579.6 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_15321.1 1 KEGG: 00240+3.1.3.89 "Pyrimidine metabolism" JAMg_model_8046.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" JAMg_model_2179.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" JAMg_model_3523.2 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" JAMg_model_8852.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" JAMg_model_17937.2 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" JAMg_model_17705.1 56 Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-350562;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-1236978;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880 "Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Regulation of ornithine decarboxylase (ODC)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Cross-presentation of soluble exogenous antigens (endosomes)";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FCERI mediated NF-kB activation";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases" JAMg_model_8784.2 3 Reactome: R-HSA-5693571;Reactome: R-HSA-3108214;Reactome: R-HSA-164843 "Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins";"2-LTR circle formation" JAMg_model_11741.4 24 Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-983189 "MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"HCMV Early Events";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"Kinesins" JAMg_model_20864.3 12 KEGG: 00680+6.2.1.1;KEGG: 00720+6.2.1.1;KEGG: 00620+6.2.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-5108;KEGG: 00640+6.2.1.1;KEGG: 00630+6.2.1.1;KEGG: 00010+6.2.1.1;MetaCyc: PWY-5133;MetaCyc: PWY-7857;MetaCyc: PWY-5132;MetaCyc: PWY-6672 "Methane metabolism";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Chitin degradation to ethanol";"L-isoleucine biosynthesis V";"Propanoate metabolism";"Glyoxylate and dicarboxylate metabolism";"Glycolysis / Gluconeogenesis";"Colupulone and cohumulone biosynthesis";"Adlupulone and adhumulone biosynthesis";"Lupulone and humulone biosynthesis";"Cis-genanyl-coa degradation" JAMg_model_12302.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_8913.1 56 Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-983168 "Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"FCERI mediated NF-kB activation";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_20280.2 2 Reactome: R-HSA-8854518;Reactome: R-HSA-6804756 "AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation" JAMg_model_16393.1 4 KEGG: 00640+4.1.1.9;Reactome: R-HSA-390247;Reactome: R-HSA-9033241;KEGG: 00410+4.1.1.9 "Propanoate metabolism";"Beta-oxidation of very long chain fatty acids";"Peroxisomal protein import";"beta-Alanine metabolism" JAMg_model_19423.1 1 Reactome: R-HSA-163125 "Post-translational modification: synthesis of GPI-anchored proteins" JAMg_model_1700.1 8 Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68827 "Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex" JAMg_model_19148.1 5 Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" JAMg_model_4541.10 7 Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942 "Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition" JAMg_model_21021.1 12 KEGG: 00500+2.7.7.9;KEGG: 00052+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-6527;MetaCyc: PWY-3801;MetaCyc: PWY-7343;Reactome: R-HSA-3322077;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-7238;KEGG: 00561+2.7.7.9;KEGG: 00520+2.7.7.9 "Starch and sucrose metabolism";"Galactose metabolism";"Formation of the active cofactor, UDP-glucuronate";"Stachyose degradation";"Sucrose degradation II (sucrose synthase)";"UDP-alpha-D-glucose biosynthesis I";"Glycogen synthesis";"Pentose and glucuronate interconversions";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose biosynthesis II";"Glycerolipid metabolism";"Amino sugar and nucleotide sugar metabolism" JAMg_model_20275.2 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" JAMg_model_10566.2 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" JAMg_model_1511.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" JAMg_model_15875.6 1 Reactome: R-HSA-8949613 "Cristae formation" JAMg_model_6658.1 1 Reactome: R-HSA-6798163 "Choline catabolism" JAMg_model_5776.9 3 Reactome: R-HSA-1614603;Reactome: R-HSA-2408508;Reactome: R-HSA-1614558 "Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine" JAMg_model_2071.2 56 Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176 "Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI2 by the proteasome";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha" JAMg_model_2777.1 14 Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-426486;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-426496 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Small interfering RNA (siRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs" JAMg_model_8428.1 10 KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-189085;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52 "Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Digestion of dietary carbohydrate";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism" JAMg_model_187.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" JAMg_model_650.7 4 KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202 "Glutathione metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines" JAMg_model_14184.1 3 MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106 "Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)" JAMg_model_18026.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" JAMg_model_2190.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" JAMg_model_13435.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_12468.2 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" JAMg_model_8629.1 2 MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4 "Cellulose degradation II (fungi)";"Starch and sucrose metabolism" JAMg_model_8220.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_10278.1 5 Reactome: R-HSA-376172;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.24;Reactome: R-HSA-171007;Reactome: R-HSA-168638 "DSCAM interactions";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"p38MAPK events";"NOD1/2 Signaling Pathway" JAMg_model_3198.2 1 Reactome: R-HSA-1483191 "Synthesis of PC" JAMg_model_8220.3 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_17344.1 4 Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554 "HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" JAMg_model_6535.1 4 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events" JAMg_model_2074.4 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" JAMg_model_19131.3 14 MetaCyc: PWY-8051;KEGG: 00565+3.1.3.4;Reactome: R-HSA-1483213;KEGG: 00561+3.1.3.4;KEGG: 00600+3.1.3.4;Reactome: R-HSA-1483191;MetaCyc: PWY-8053;MetaCyc: PWY-7782;Reactome: R-HSA-75109;Reactome: R-HSA-4419969;MetaCyc: PWY-8052;KEGG: 00564+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8055 "Anandamide biosynthesis I";"Ether lipid metabolism";"Synthesis of PE";"Glycerolipid metabolism";"Sphingolipid metabolism";"Synthesis of PC";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Triglyceride biosynthesis";"Depolymerisation of the Nuclear Lamina";"2-arachidonoylglycerol biosynthesis";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis" JAMg_model_10182.5 5 Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-983231;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878 "MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Factors involved in megakaryocyte development and platelet production";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport" JAMg_model_456.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1" JAMg_model_12749.3 12 Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813 "HCMV Early Events";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Separation of Sister Chromatids" JAMg_model_13470.1 16 Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553 "Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs" JAMg_model_20391.3 4 MetaCyc: PWY-7221;KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817;KEGG: 00983+6.3.5.2 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes" JAMg_model_11061.2 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" JAMg_model_10562.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" JAMg_model_17269.5 3 MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106 "Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)" JAMg_model_17354.1 21 Reactome: R-HSA-202424;Reactome: R-HSA-9020702;Reactome: R-HSA-1810476;Reactome: R-HSA-933543;Reactome: R-HSA-1169091;Reactome: R-HSA-5357905;Reactome: R-HSA-168927;Reactome: R-HSA-1236974;Reactome: R-HSA-975144;Reactome: R-HSA-937041;Reactome: R-HSA-5603029;Reactome: R-HSA-5357956;Reactome: R-HSA-2871837;Reactome: R-HSA-933542;Reactome: R-HSA-937039;Reactome: R-HSA-5602636;Reactome: R-HSA-5684264;Reactome: R-HSA-445989;Reactome: R-HSA-5603027;Reactome: R-HSA-5607764;Reactome: R-HSA-168638 "Downstream TCR signaling";"Interleukin-1 signaling";"RIP-mediated NFkB activation via ZBP1";"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10";"Activation of NF-kappaB in B cells";"Regulation of TNFR1 signaling";"TICAM1, RIP1-mediated IKK complex recruitment";"ER-Phagosome pathway";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IKK complex recruitment mediated by RIP1";"IkBA variant leads to EDA-ID";"TNFR1-induced NFkappaB signaling pathway";"FCERI mediated NF-kB activation";"TRAF6 mediated NF-kB activation";"IRAK1 recruits IKK complex";"IKBKB deficiency causes SCID";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)";"CLEC7A (Dectin-1) signaling";"NOD1/2 Signaling Pathway" JAMg_model_13133.1 1 Reactome: R-HSA-5676934 "Protein repair" JAMg_model_2312.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" JAMg_model_15252.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport" JAMg_model_18865.2 6 Reactome: R-HSA-977347;KEGG: 00270+2.6.1.52;MetaCyc: PWY-8010;KEGG: 00260+2.6.1.52;KEGG: 00680+2.6.1.52;KEGG: 00750+2.6.1.52 "Serine biosynthesis";"Cysteine and methionine metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Glycine, serine and threonine metabolism";"Methane metabolism";"Vitamin B6 metabolism" JAMg_model_11797.1 16 Reactome: R-HSA-8936459;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX" JAMg_model_8433.1 1 Reactome: R-HSA-2514859 "Inactivation, recovery and regulation of the phototransduction cascade" JAMg_model_519.1 1 Reactome: R-HSA-6798163 "Choline catabolism" JAMg_model_15905.1 3 Reactome: R-HSA-5632968;Reactome: R-HSA-5632928;Reactome: R-HSA-5358565 "Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)" JAMg_model_16117.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" JAMg_model_20768.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259 "Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism" JAMg_model_9236.2 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" JAMg_model_19376.1 5 Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-427413;Reactome: R-HSA-5334118 "PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"NoRC negatively regulates rRNA expression";"DNA methylation" JAMg_model_7169.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" JAMg_model_11141.1 2 KEGG: 00970+6.1.1.9;Reactome: R-HSA-189085 "Aminoacyl-tRNA biosynthesis";"Digestion of dietary carbohydrate" JAMg_model_14065.2 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" JAMg_model_9719.1 2 KEGG: 00230+4.6.1.1;Reactome: R-HSA-196819 "Purine metabolism";"Vitamin B1 (thiamin) metabolism" JAMg_model_8875.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_10992.7 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" JAMg_model_16422.3 6 KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-416993;Reactome: R-HSA-76005;Reactome: R-HSA-114516;Reactome: R-HSA-5099900 "Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation";"WNT5A-dependent internalization of FZD4" JAMg_model_8752.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_10328.5 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" JAMg_model_15974.3 10 MetaCyc: PWY-7003;KEGG: 00710+2.7.2.3;Reactome: R-HSA-70171;Reactome: R-HSA-70263;MetaCyc: PWY-8004;MetaCyc: PWY-6886;KEGG: 00010+2.7.2.3;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-1042 "Glycerol degradation to butanol";"Carbon fixation in photosynthetic organisms";"Glycolysis";"Gluconeogenesis";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)" JAMg_model_8408.1 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_12123.1 3 Reactome: R-HSA-1236974;Reactome: R-HSA-9609523;Reactome: R-HSA-1799339 "ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane" JAMg_model_17309.2 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" JAMg_model_12979.3 18 MetaCyc: PWY-7221;MetaCyc: PWY-7187;MetaCyc: PWY-6545;Reactome: R-HSA-499943;MetaCyc: PWY-7205;MetaCyc: PWY-7222;MetaCyc: PWY-7224;MetaCyc: PWY-7176;MetaCyc: PWY-7227;MetaCyc: PWY-7220;MetaCyc: PWY-7198;MetaCyc: PWY-7210;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7197;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7226;KEGG: 00230+2.7.4.6 "Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"CMP phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism" JAMg_model_13508.3 3 Reactome: R-HSA-913709;Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "O-linked glycosylation of mucins";"Keratan sulfate biosynthesis";"N-Glycan antennae elongation" JAMg_model_19892.1 10 Reactome: R-HSA-6798695;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2160916;MetaCyc: PWY-6807;Reactome: R-HSA-2024096;Reactome: R-HSA-2206292 "Neutrophil degranulation";"Galactose metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Xyloglucan degradation II (exoglucanase)";"HS-GAG degradation";"MPS VII - Sly syndrome" JAMg_model_15020.2 2 Reactome: R-HSA-5663220;Reactome: R-HSA-376176 "RHO GTPases Activate Formins";"Signaling by ROBO receptors" JAMg_model_15039.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" JAMg_model_16243.2 1 Reactome: R-HSA-1483148 "Synthesis of PG" JAMg_model_11988.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-6790901 "Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol" JAMg_model_9776.1 5 Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-73772 "NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape" JAMg_model_16138.1 20 KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7726;MetaCyc: PWY-7007;MetaCyc: PWY-5136;Reactome: R-HSA-9033241;MetaCyc: PWY-7340;MetaCyc: PWY-6920;MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7337;MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7288;MetaCyc: PWY-735;MetaCyc: PWY-7854;MetaCyc: PWY-7291 "Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Peroxisomal protein import";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)" JAMg_model_4165.2 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" JAMg_model_8721.2 3 Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282 "HS-GAG degradation";"Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B" JAMg_model_2691.1 7 MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-7214 "Matairesinol biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)" JAMg_model_1149.1 4 MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2 "2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation" JAMg_model_10021.2 4 Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1;MetaCyc: PWY-4841;KEGG: 00562+1.13.99.1 "Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Inositol phosphate metabolism" JAMg_model_5994.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" JAMg_model_1387.1 7 Reactome: R-HSA-380972;Reactome: R-HSA-5674400;Reactome: R-HSA-8854214;Reactome: R-HSA-198323;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-165181 "Energy dependent regulation of mTOR by LKB1-AMPK";"Constitutive Signaling by AKT1 E17K in Cancer";"TBC/RABGAPs";"AKT phosphorylates targets in the cytosol";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB" JAMg_model_990.1 14 KEGG: 00260+2.1.2.1;MetaCyc: PWY-1622;MetaCyc: PWY-2201;MetaCyc: PWY-5497;KEGG: 00670+2.1.2.1;MetaCyc: PWY-3661-1;MetaCyc: PWY-181;MetaCyc: PWY-3661;MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00680+2.1.2.1;KEGG: 00630+2.1.2.1;MetaCyc: PWY-3841;KEGG: 00460+2.1.2.1 "Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)";"Folate transformations I";"Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"Glycine betaine degradation II (mammalian)";"Photorespiration ";"Glycine betaine degradation I";"Folate polyglutamylation";"Metabolism of folate and pterines";"Methane metabolism";"Glyoxylate and dicarboxylate metabolism";"Folate transformations II (plants)";"Cyanoamino acid metabolism" JAMg_model_4834.3 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" JAMg_model_17532.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_11090.1 4 Reactome: R-HSA-8874211;Reactome: R-HSA-8963889;Reactome: R-HSA-1655829;Reactome: R-HSA-381033 "CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones" JAMg_model_19550.3 56 Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785 "Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Interleukin-1 signaling";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FCERI mediated NF-kB activation";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome" JAMg_model_4160.2 4 Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825 "DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis" JAMg_model_7052.5 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" JAMg_model_14230.1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" JAMg_model_1898.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_13953.1 13 Reactome: R-HSA-416482;Reactome: R-HSA-4420097;Reactome: R-HSA-416572;Reactome: R-HSA-5627117;Reactome: R-HSA-3928662;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3928663;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1 "G alpha (12/13) signalling events";"VEGFA-VEGFR2 Pathway";"Sema4D induced cell migration and growth-cone collapse";"RHO GTPases Activate ROCKs";"EPHB-mediated forward signaling";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"EPHA-mediated growth cone collapse";"PI3K-Akt signaling pathway";"mTOR signaling pathway" JAMg_model_13966.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" JAMg_model_14172.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" JAMg_model_20279.2 4 MetaCyc: PWY-5028;KEGG: 00340+3.5.2.7;Reactome: R-HSA-70921;MetaCyc: PWY-5030 "L-histidine degradation II";"Histidine metabolism";"Histidine catabolism";"L-histidine degradation III" JAMg_model_20404.2 10 MetaCyc: PWY-5484;KEGG: 00710+5.3.1.1;KEGG: 00562+5.3.1.1;MetaCyc: PWY-1042;KEGG: 00010+5.3.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-7003;Reactome: R-HSA-70171;MetaCyc: PWY-6142;KEGG: 00051+5.3.1.1 "Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Inositol phosphate metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Glycerol degradation to butanol";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Fructose and mannose metabolism" JAMg_model_2132.3 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" JAMg_model_19162.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" JAMg_model_16170.1 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" JAMg_model_4961.5 5 Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-182971 "InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation" JAMg_model_20362.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_19431.2 13 Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957 "SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" JAMg_model_6502.1 1 Reactome: R-HSA-6798163 "Choline catabolism" JAMg_model_10609.2 5 MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749;Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16 "UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism" JAMg_model_11756.2 2 Reactome: R-HSA-390918;Reactome: R-HSA-9033241 "Peroxisomal lipid metabolism";"Peroxisomal protein import" JAMg_model_20389.2 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" JAMg_model_1310.2 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" JAMg_model_5074.2 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" JAMg_model_14553.1 8 Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-68952 "Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"Removal of the Flap Intermediate";"Polymerase switching";"DNA replication initiation" JAMg_model_8452.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_6807.9 5 KEGG: 00720+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00630+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3 "Carbon fixation pathways in prokaryotes";"Iron uptake and transport";"Glyoxylate and dicarboxylate metabolism";"Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)" JAMg_model_3525.2 5 Reactome: R-HSA-901042;Reactome: R-HSA-879415;Reactome: R-HSA-532668;Reactome: R-HSA-381426;Reactome: R-HSA-8957275 "Calnexin/calreticulin cycle";"Advanced glycosylation endproduct receptor signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation" JAMg_model_15505.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" JAMg_model_6855.1 69 Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;MetaCyc: PWY-3841;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;KEGG: 00720+6.3.4.3;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;MetaCyc: PWY-1722;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;KEGG: 00670+1.5.1.5+3.5.4.9;Reactome: R-HSA-5676590;MetaCyc: PWY-2201;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;MetaCyc: PWY-2161;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;MetaCyc: PWY-7909;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;MetaCyc: PWY-5497;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-196757;MetaCyc: PWY-5030;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;KEGG: 00670+6.3.4.3;Reactome: R-HSA-5687128;Reactome: R-HSA-8939902;Reactome: R-HSA-349425 "Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Folate transformations II (plants)";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Carbon fixation pathways in prokaryotes";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Formate assimilation into 5,10-methylenetetrahydrofolate";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"G2/M Checkpoints";"Carbon fixation pathways in prokaryotes";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"One carbon pool by folate";"NIK-->noncanonical NF-kB signaling";"Folate transformations I";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"Folate polyglutamylation";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Formaldehyde oxidation VII (THF pathway)";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Purine nucleobases degradation II (anaerobic)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Metabolism of folate and pterines";"L-histidine degradation III";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"One carbon pool by folate";"MAPK6/MAPK4 signaling";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1" JAMg_model_19608.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" JAMg_model_19812.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_15729.2 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" JAMg_model_3020.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" JAMg_model_20249.3 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" JAMg_model_9837.3 8 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Thermogenesis";"Relaxin signaling pathway" JAMg_model_8826.2 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" JAMg_model_1523.2 2 Reactome: R-HSA-8949613;Reactome: R-HSA-1268020 "Cristae formation";"Mitochondrial protein import" JAMg_model_11342.2 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" JAMg_model_19655.2 3 KEGG: 00860+2.5.1.141;MetaCyc: PWY-7856;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"Heme a biosynthesis";"Heme biosynthesis" JAMg_model_10844.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_10392.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" JAMg_model_13782.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394 "Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER" JAMg_model_17072.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_696.1 5 Reactome: R-HSA-450321;Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-450341 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors" JAMg_model_11883.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6807505 "Protein ubiquitination";"RNA polymerase II transcribes snRNA genes" JAMg_model_14961.4 4 Reactome: R-HSA-389661;KEGG: 00785+2.8.1.8;MetaCyc: PWY-7382;MetaCyc: PWY-6987 "Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)" JAMg_model_13258.2 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" JAMg_model_21355.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" JAMg_model_3132.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" JAMg_model_4336.2 34 Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-9639288;Reactome: R-HSA-5663220;Reactome: R-HSA-4085377;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-168276;Reactome: R-HSA-4551638 "SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Amino acids regulate mTORC1";"RHO GTPases Activate Formins";"SUMOylation of SUMOylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways";"SUMOylation of chromatin organization proteins" JAMg_model_4775.1 2 KEGG: 00760+2.7.1.173+2.7.1.22;MetaCyc: PWY-5381 "Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)" JAMg_model_8806.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" JAMg_model_13502.1 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_8653.1 3 Reactome: R-HSA-727802;Reactome: R-HSA-5619078;Reactome: R-HSA-6787639 "Transport of nucleotide sugars";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)";"GDP-fucose biosynthesis" JAMg_model_20334.9 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" JAMg_model_8505.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" JAMg_model_8153.9 3 Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3 "Serine biosynthesis";"Methane metabolism";"Glycine, serine and threonine metabolism" JAMg_model_3810.2 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" JAMg_model_957.6 4 Reactome: R-HSA-6811434;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1";"MHC class II antigen presentation";"Kinesins" JAMg_model_21315.2 15 MetaCyc: PWY-5723;MetaCyc: PWY-2221;MetaCyc: PWY-8004;MetaCyc: PWY-6886;MetaCyc: PWY-7218;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-7383;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6142;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7003;Reactome: R-HSA-70171 "Rubisco shunt";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Purine metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pyruvate metabolism";"Glycerol degradation to butanol";"Glycolysis" JAMg_model_19272.7 2 Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22 "Histidine catabolism";"Histidine metabolism" JAMg_model_2197.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" JAMg_model_18324.3 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" JAMg_model_6691.3 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733 "Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis" JAMg_model_639.3 24 Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-68877;Reactome: R-HSA-9609690 "RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Kinesins";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"Mitotic Prometaphase";"HCMV Early Events" JAMg_model_17325.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" JAMg_model_7894.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-2173788 "UCH proteinases";"Downregulation of TGF-beta receptor signaling" JAMg_model_21053.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-936837 "Neutrophil degranulation";"Ion transport by P-type ATPases" JAMg_model_7496.4 4 Reactome: R-HSA-982772;Reactome: R-HSA-1170546;Reactome: R-HSA-983231;Reactome: R-HSA-2586552 "Growth hormone receptor signaling";"Prolactin receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin" JAMg_model_8721.1 3 Reactome: R-HSA-2206282;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.50 "MPS IIIB - Sanfilippo syndrome B";"HS-GAG degradation";"Glycosaminoglycan degradation" JAMg_model_17695.2 7 Reactome: R-HSA-445095;Reactome: R-HSA-6798695;Reactome: R-HSA-373753;Reactome: R-HSA-264870;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001 "Interaction between L1 and Ankyrins";"Neutrophil degranulation";"Nephrin family interactions";"Caspase-mediated cleavage of cytoskeletal proteins";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade" JAMg_model_11119.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" JAMg_model_20673.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" JAMg_model_19116.3 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_16510.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" JAMg_model_14158.2 10 KEGG: 00230+3.5.2.17;MetaCyc: PWY-5691;Reactome: R-HSA-975634;MetaCyc: PWY-7394;Reactome: R-HSA-977225;Reactome: R-HSA-3000171;Reactome: R-HSA-6798695;Reactome: R-HSA-2453902;MetaCyc: PWY-7849;Reactome: R-HSA-2453864 "Purine metabolism";"Urate conversion to allantoin I";"Retinoid metabolism and transport";"Urate conversion to allantoin II";"Amyloid fiber formation";"Non-integrin membrane-ECM interactions";"Neutrophil degranulation";"The canonical retinoid cycle in rods (twilight vision)";"Urate conversion to allantoin III";"Retinoid cycle disease events" JAMg_model_21338.2 1 Reactome: R-HSA-71384 "Ethanol oxidation" JAMg_model_7324.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" JAMg_model_2242.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" JAMg_model_18166.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-1834949 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA" JAMg_model_5783.1 6 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557;Reactome: R-HSA-1222556 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"T cell receptor signaling pathway";"Signaling by SCF-KIT";"ROS and RNS production in phagocytes" JAMg_model_15311.4 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_8159.5 12 MetaCyc: PWY-6142;MetaCyc: PWY-1861;Reactome: R-HSA-70171;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00710+4.1.2.13;KEGG: 00680+4.1.2.13;KEGG: 00030+4.1.2.13;KEGG: 00051+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-1042;MetaCyc: PWY-5484 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Pentose phosphate pathway";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)" JAMg_model_10889.3 8 KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1 "Galactose metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Glycolysis";"Amino sugar and nucleotide sugar metabolism" JAMg_model_10802.1 2 Reactome: R-HSA-432720;Reactome: R-HSA-432722 "Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis" JAMg_model_10689.4 6 Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-6791226 "mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_12327.1 24 Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295 "Kinesins";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"Mitotic Prometaphase";"HCMV Early Events";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Aggrephagy";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation" JAMg_model_21029.1 15 Reactome: R-HSA-5467340;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-3769402;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-5467337;Reactome: R-HSA-5689896;Reactome: R-HSA-5467333;Reactome: R-HSA-5358749;Reactome: R-HSA-195253;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-111465;Reactome: R-HSA-5358752 "AXIN missense mutants destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Ovarian tumor domain proteases";"APC truncation mutants are not K63 polyubiquitinated";"S37 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Apoptotic cleavage of cellular proteins";"T41 mutants of beta-catenin aren't phosphorylated" JAMg_model_20404.1 10 KEGG: 00051+5.3.1.1;MetaCyc: PWY-6142;Reactome: R-HSA-70171;MetaCyc: PWY-7003;KEGG: 00010+5.3.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-5484;KEGG: 00710+5.3.1.1;KEGG: 00562+5.3.1.1;MetaCyc: PWY-1042 "Fructose and mannose metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Inositol phosphate metabolism";"Glycolysis IV (plant cytosol)" JAMg_model_1093.1 24 Reactome: R-HSA-418555;Reactome: R-HSA-500657;Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-392451;Reactome: R-HSA-8964315;Reactome: R-HSA-416476;Reactome: R-HSA-420092;Reactome: R-HSA-418597;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-416482;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-418217;Reactome: R-HSA-381676;Reactome: R-HSA-428930;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-9009391;Reactome: R-HSA-392851;Reactome: R-HSA-392170;Reactome: R-HSA-4086398 "G alpha (s) signalling events";"Presynaptic function of Kainate receptors";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through PI3Kgamma";"G beta:gamma signalling through BTK";"G alpha (q) signalling events";"Glucagon-type ligand receptors";"G alpha (z) signalling events";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PLC beta";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thromboxane signalling through TP receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Extra-nuclear estrogen signaling";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 12";"Ca2+ pathway" JAMg_model_2173.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" JAMg_model_3590.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" JAMg_model_13551.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-68884;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295 "Kinesins";"Mitotic Telophase/Cytokinesis";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" JAMg_model_17671.3 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" JAMg_model_5574.6 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" JAMg_model_19491.4 4 Reactome: R-HSA-947581;Reactome: R-HSA-1362409;KEGG: 00730+2.8.1.7;MetaCyc: PWY-7250 "Molybdenum cofactor biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Thiamine metabolism";"[2Fe-2S] iron-sulfur cluster biosynthesis" JAMg_model_9473.1 8 MetaCyc: PWY-241;MetaCyc: PWY-5744;MetaCyc: PWY-6142;MetaCyc: PWY-5743;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-7115;MetaCyc: PWY-5789 "C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle" JAMg_model_4116.7 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" JAMg_model_17363.1 29 Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-6782210;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-73863;Reactome: R-HSA-167160;Reactome: R-HSA-427413;Reactome: R-HSA-674695;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-5696400;Reactome: R-HSA-73776;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-5696395;Reactome: R-HSA-167200;Reactome: R-HSA-73762 "Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"Dual Incision in GG-NER";"RNA Polymerase II Promoter Escape";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of Incision Complex in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Transcription Initiation" JAMg_model_16879.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_11978.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-5689880 "Protein ubiquitination";"Ub-specific processing proteases" JAMg_model_18152.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_10713.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" JAMg_model_17283.5 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_6333.1 10 MetaCyc: PWY-7996;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5891;Reactome: R-HSA-2142789;MetaCyc: PWY-5890;MetaCyc: PWY-5849;MetaCyc: PWY-5839;MetaCyc: PWY-5892;MetaCyc: PWY-5844;MetaCyc: PWY-5895 "Menaquinol-4 biosynthesis I";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-11 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-13 biosynthesis" JAMg_model_1364.2 1 Reactome: R-HSA-1483101 "Synthesis of PS" JAMg_model_2157.1 1 Reactome: R-HSA-189451 "Heme biosynthesis" JAMg_model_18438.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_13230.2 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" JAMg_model_21161.4 7 Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259 "AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes" JAMg_model_1639.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_5067.4 1 Reactome: R-HSA-8949613 "Cristae formation" JAMg_model_11411.3 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" JAMg_model_12220.1 1 Reactome: R-HSA-163841 "Gamma carboxylation, hypusine formation and arylsulfatase activation" JAMg_model_2446.3 5 Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-3214815 "RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones" JAMg_model_19551.2 6 Reactome: R-HSA-4793952;MetaCyc: PWY-7920;MetaCyc: PWY-7426;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143 "Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis" JAMg_model_7931.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041 "Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis" JAMg_model_1124.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" JAMg_model_2764.3 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" JAMg_model_17998.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" JAMg_model_8897.6 3 Reactome: R-HSA-1268020;Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Mitochondrial protein import";"Complex I biogenesis";"Respiratory electron transport" JAMg_model_2047.2 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" JAMg_model_1555.2 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_5072.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_18508.1 1 Reactome: R-HSA-6787639 "GDP-fucose biosynthesis" JAMg_model_20540.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" JAMg_model_1151.8 1 Reactome: R-HSA-8950505 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" JAMg_model_21325.1 1 Reactome: R-HSA-2024096 "HS-GAG degradation" JAMg_model_6758.2 7 Reactome: R-HSA-71403;MetaCyc: PWY-5084;KEGG: 00380+2.3.1.61;KEGG: 00310+2.3.1.61;KEGG: 00020+2.3.1.61;Reactome: R-HSA-71064;Reactome: R-HSA-389661 "Citric acid cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Lysine degradation";"Citrate cycle (TCA cycle)";"Lysine catabolism";"Glyoxylate metabolism and glycine degradation" JAMg_model_16031.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-9018519;Reactome: R-HSA-2500257;Reactome: R-HSA-3108214;Reactome: R-HSA-2468052;Reactome: R-HSA-1221632;Reactome: R-HSA-2470946 "Separation of Sister Chromatids";"Estrogen-dependent gene expression";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Establishment of Sister Chromatid Cohesion";"Meiotic synapsis";"Cohesin Loading onto Chromatin" JAMg_model_9932.3 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_11724.3 13 Reactome: R-HSA-156590;MetaCyc: PWY-6842;KEGG: 00053+1.8.5.1;MetaCyc: PWY-7112;MetaCyc: PWY-2261;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-4061;KEGG: 00480+2.5.1.18+1.8.5.1;Reactome: R-HSA-196836;KEGG: 00980+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6370 "Glutathione conjugation";"Glutathione-mediated detoxification II";"Ascorbate and aldarate metabolism";"4-hydroxy-2-nonenal detoxification";"Ascorbate glutathione cycle";"Drug metabolism - other enzymes";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Vitamin C (ascorbate) metabolism";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"Ascorbate recycling (cytosolic)" JAMg_model_16078.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" JAMg_model_10602.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" JAMg_model_6357.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" JAMg_model_18135.2 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" JAMg_model_21190.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012 "L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency" JAMg_model_8900.2 2 Reactome: R-HSA-1268020;Reactome: R-HSA-71403 "Mitochondrial protein import";"Citric acid cycle (TCA cycle)" JAMg_model_15154.2 1 KEGG: 00051+4.2.1.68 "Fructose and mannose metabolism" JAMg_model_10797.3 1 Reactome: R-HSA-5676934 "Protein repair" JAMg_model_7364.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8951664 "Neutrophil degranulation";"Neddylation" JAMg_model_10890.1 3 Reactome: R-HSA-8951664;Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Neddylation";"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" JAMg_model_18868.2 4 Reactome: R-HSA-72731;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174 "Recycling of eIF2:GDP";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" JAMg_model_2848.1 12 MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-5392;MetaCyc: PWY-6969;MetaCyc: PWY-5913;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5537;KEGG: 00720+6.2.1.5 "Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes" JAMg_model_9525.1 10 KEGG: 04926+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 05163+2.7.11.1;Reactome: R-HSA-201722 "Relaxin signaling pathway";"Ub-specific processing proteases";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"HATs acetylate histones";"Human cytomegalovirus infection";"Formation of the beta-catenin:TCF transactivating complex" JAMg_model_6678.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_13056.2 13 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956 "Peptide chain elongation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" JAMg_model_9732.1 7 KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;KEGG: 00030+3.1.1.31;MetaCyc: PWY-5514;MetaCyc: PWY-6906;Reactome: R-HSA-71336;MetaCyc: PWY-8004 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Pentose phosphate pathway";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation";"Pentose phosphate pathway";"Entner-Doudoroff pathway I" JAMg_model_15092.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_8436.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_1596.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_823.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" JAMg_model_2446.5 5 Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-73762 "Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation" JAMg_model_20989.2 1 Reactome: R-HSA-5620924 "Intraflagellar transport" JAMg_model_5303.5 4 KEGG: 00510+2.7.1.108;MetaCyc: PWY-6129;Reactome: R-HSA-4755583;Reactome: R-HSA-446199 "N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Defective DOLK causes DOLK-CDG (CDG-1m)";"Synthesis of Dolichyl-phosphate" JAMg_model_155.4 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" JAMg_model_3454.5 3 MetaCyc: PWY-6619;Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20 "Adenine and adenosine salvage VI";"Purine salvage";"Purine metabolism" JAMg_model_6694.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" JAMg_model_3727.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" JAMg_model_19162.5 1 Reactome: R-HSA-163560 "Triglyceride catabolism" JAMg_model_19003.4 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_156.3 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_6710.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" JAMg_model_2003.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259 "AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes" JAMg_model_12749.7 12 Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813 "HCMV Early Events";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Separation of Sister Chromatids" JAMg_model_19888.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" JAMg_model_8124.2 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" JAMg_model_13788.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-6798695 "Glycosphingolipid metabolism";"Neutrophil degranulation" JAMg_model_8047.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" JAMg_model_4124.1 12 MetaCyc: PWY-5872;Reactome: R-HSA-2142789;MetaCyc: PWY-5873;MetaCyc: PWY-5855;MetaCyc: PWY-7230;MetaCyc: PWY-6708;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5871;MetaCyc: PWY-5857;MetaCyc: PWY-5856;MetaCyc: PWY-7233;MetaCyc: PWY-5870 "Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)" JAMg_model_21049.2 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" JAMg_model_1565.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" JAMg_model_18116.1 2 Reactome: R-HSA-163282;Reactome: R-HSA-2151201 "Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis" JAMg_model_6046.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" JAMg_model_6612.2 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" JAMg_model_19162.6 1 Reactome: R-HSA-163560 "Triglyceride catabolism" JAMg_model_16027.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_11490.1 3 Reactome: R-HSA-8876725;KEGG: 00310+2.1.1.60;Reactome: R-HSA-2514859 "Protein methylation";"Lysine degradation";"Inactivation, recovery and regulation of the phototransduction cascade" JAMg_model_9553.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" JAMg_model_8288.2 4 Reactome: R-HSA-9020702;Reactome: R-HSA-975144;MetaCyc: PWY-7511;Reactome: R-HSA-937039 "Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Protein ubiquitination";"IRAK1 recruits IKK complex" JAMg_model_19352.1 2 KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668 "Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" JAMg_model_3662.5 16 Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-6791226 "L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_3198.3 1 Reactome: R-HSA-1483191 "Synthesis of PC" JAMg_model_9955.1 56 Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-8941858 "CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity" JAMg_model_12435.1 1 Reactome: R-HSA-1632852 "Macroautophagy" JAMg_model_4123.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_13050.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_10797.4 1 Reactome: R-HSA-5676934 "Protein repair" JAMg_model_5740.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" JAMg_model_17154.1 6 Reactome: R-HSA-139915;Reactome: R-HSA-6803211;Reactome: R-HSA-6803207;Reactome: R-HSA-6803205;Reactome: R-HSA-6803204;Reactome: R-HSA-6804759 "Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Regulation of TP53 Activity through Association with Co-factors" JAMg_model_9184.8 6 KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107 "Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" JAMg_model_19008.1 11 Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-5689880;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-3214847;Reactome: R-HSA-73779 "RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Ub-specific processing proteases";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"HATs acetylate histones";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" JAMg_model_6805.3 1 Reactome: R-HSA-5635838 "Activation of SMO" JAMg_model_8992.3 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_16624.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" JAMg_model_3148.3 8 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Signaling by Hippo";"Human immunodeficiency virus 1 infection" JAMg_model_6653.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" JAMg_model_21356.4 9 Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-167172 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome" JAMg_model_9141.4 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" JAMg_model_2286.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" JAMg_model_12819.1 6 Reactome: R-HSA-9028731;Reactome: R-HSA-5654706;Reactome: R-HSA-5654700;Reactome: R-HSA-5654693;Reactome: R-HSA-5673001;Reactome: R-HSA-5654712 "Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR1 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR4 signaling" JAMg_model_3181.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" JAMg_model_6608.2 19 KEGG: 00720+2.3.3.8;MetaCyc: PWY-6728;Reactome: R-HSA-6798695;MetaCyc: PWY-5538;MetaCyc: PWY-5172;Reactome: R-HSA-163765;KEGG: 00720+6.2.1.5;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5392;MetaCyc: PWY-7384;Reactome: R-HSA-75105;MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5537;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-5913;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5 "Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Neutrophil degranulation";"Pyruvate fermentation to acetate VI";"Acetyl-coa biosynthesis III (from citrate)";"ChREBP activates metabolic gene expression";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Fatty acyl-CoA biosynthesis";"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Propanoate metabolism";"Citrate cycle (TCA cycle)" JAMg_model_16071.3 9 Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-114608;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952 "Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Platelet degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions" JAMg_model_14501.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_6457.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" JAMg_model_5614.2 7 Reactome: R-HSA-3371453;Reactome: R-HSA-983170;Reactome: R-HSA-381183;Reactome: R-HSA-381070;Reactome: R-HSA-114608;Reactome: R-HSA-381042;Reactome: R-HSA-381033 "Regulation of HSF1-mediated heat shock response";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperone genes";"IRE1alpha activates chaperones";"Platelet degranulation";"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperones" JAMg_model_18188.4 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_9755.5 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" JAMg_model_19793.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_13908.1 2 Reactome: R-HSA-73621;Reactome: R-HSA-73614 "Pyrimidine catabolism";"Pyrimidine salvage" JAMg_model_7864.3 3 Reactome: R-HSA-6811434;Reactome: R-HSA-390471;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins" JAMg_model_14329.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" JAMg_model_19376.2 5 Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-427413;Reactome: R-HSA-5334118 "PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"NoRC negatively regulates rRNA expression";"DNA methylation" JAMg_model_13414.1 4 KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;MetaCyc: PWY-6483;Reactome: R-HSA-1660662 "Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Ceramide degradation (generic)";"Glycosphingolipid metabolism" JAMg_model_18152.4 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_15465.2 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" JAMg_model_137.1 6 KEGG: 00290+4.2.1.33;Reactome: R-HSA-71403;KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3;Reactome: R-HSA-1268020;KEGG: 00720+4.2.1.3 "Valine, leucine and isoleucine biosynthesis";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Mitochondrial protein import";"Carbon fixation pathways in prokaryotes" JAMg_model_1689.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_4423.1 4 MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2;Reactome: R-HSA-70688;MetaCyc: PWY-6922 "(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism";"Proline catabolism";"L-Ndelta-acetylornithine biosynthesis" JAMg_model_974.3 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" JAMg_model_16889.2 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" JAMg_model_450.3 1 Reactome: R-HSA-8964038 "LDL clearance" JAMg_model_4604.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" JAMg_model_715.3 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" JAMg_model_17015.3 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" JAMg_model_797.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_4998.2 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" JAMg_model_2683.2 2 Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7 "Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis" JAMg_model_12948.2 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" JAMg_model_17901.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" JAMg_model_11740.6 9 Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-6784531;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-113501 "DNA replication initiation";"Removal of the Flap Intermediate";"Polymerase switching";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"tRNA processing in the nucleus";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1" JAMg_model_17459.2 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" JAMg_model_855.3 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" JAMg_model_21260.2 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" JAMg_model_20853.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" JAMg_model_2512.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" JAMg_model_21183.3 6 KEGG: 00040+1.1.1.22;KEGG: 00520+1.1.1.22;KEGG: 00053+1.1.1.22;MetaCyc: PWY-7346;Reactome: R-HSA-173599;MetaCyc: PWY-7820 "Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"Ascorbate and aldarate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Formation of the active cofactor, UDP-glucuronate";"Teichuronic acid biosynthesis (B. subtilis 168)" JAMg_model_3368.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" JAMg_model_10342.1 2 Reactome: R-HSA-164843;Reactome: R-HSA-5693571 "2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)" JAMg_model_1988.2 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" JAMg_model_20129.1 13 MetaCyc: PWY-7112;KEGG: 00053+1.8.5.1;Reactome: R-HSA-156590;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-7533;MetaCyc: PWY-2261;KEGG: 00983+2.5.1.18;Reactome: R-HSA-196836;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-6370;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18 "4-hydroxy-2-nonenal detoxification";"Ascorbate and aldarate metabolism";"Glutathione conjugation";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Ascorbate glutathione cycle";"Drug metabolism - other enzymes";"Vitamin C (ascorbate) metabolism";"Glutathione metabolism";"Ascorbate recycling (cytosolic)";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450" JAMg_model_7757.3 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" JAMg_model_14134.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" JAMg_model_9895.8 10 MetaCyc: PWY-6317;MetaCyc: PWY-7344;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-3821;MetaCyc: PWY-6397;Reactome: R-HSA-70370;MetaCyc: PWY-7328;KEGG: 00520+5.1.3.2;Reactome: R-HSA-5609977 "D-galactose degradation I (Leloir pathway)";"UDP-alpha-D-galactose biosynthesis";"Galactose metabolism";"Stachyose degradation";"D-galactose detoxification";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose catabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)" JAMg_model_5081.1 7 Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-176187 "Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"Activation of ATR in response to replication stress" JAMg_model_20205.3 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" JAMg_model_2483.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975957 "Viral mRNA Translation";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" JAMg_model_20614.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_2931.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" JAMg_model_7496.3 4 Reactome: R-HSA-983231;Reactome: R-HSA-2586552;Reactome: R-HSA-982772;Reactome: R-HSA-1170546 "Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin";"Growth hormone receptor signaling";"Prolactin receptor signaling" JAMg_model_2887.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" JAMg_model_10101.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" JAMg_model_20428.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" JAMg_model_17734.2 5 MetaCyc: PWY-5189;Reactome: R-HSA-189451;KEGG: 00860+4.2.1.24;MetaCyc: PWY-5188;Reactome: R-HSA-6798695 "Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Neutrophil degranulation" JAMg_model_19272.3 2 Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22 "Histidine catabolism";"Histidine metabolism" JAMg_model_7362.4 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_14960.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_12139.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" JAMg_model_12417.1 1 Reactome: R-HSA-3000171 "Non-integrin membrane-ECM interactions" JAMg_model_16816.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" JAMg_model_16933.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_11685.3 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" JAMg_model_21185.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_3571.1 5 Reactome: R-HSA-6798695;KEGG: 00561+2.3.1.20;Reactome: R-HSA-75109;KEGG: 00073+2.3.1.20;Reactome: R-HSA-1482883 "Neutrophil degranulation";"Glycerolipid metabolism";"Triglyceride biosynthesis";"Cutin, suberine and wax biosynthesis";"Acyl chain remodeling of DAG and TAG" JAMg_model_19550.1 56 Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-75815 "SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D" JAMg_model_8698.7 22 Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7728;MetaCyc: PWY-7592;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7606;MetaCyc: PWY-6958;MetaCyc: PWY-7726;MetaCyc: PWY-7035;MetaCyc: PWY-5353;MetaCyc: PWY-7727;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7049;MetaCyc: PWY-5080;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7053 "Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Docosahexaenoate biosynthesis I (lower eukaryotes)" JAMg_model_6160.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_16322.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" JAMg_model_2007.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" JAMg_model_17235.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" JAMg_model_20541.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" JAMg_model_6030.3 2 Reactome: R-HSA-5689880;Reactome: R-HSA-1632852 "Ub-specific processing proteases";"Macroautophagy" JAMg_model_18100.4 1 Reactome: R-HSA-1632852 "Macroautophagy" JAMg_model_4970.2 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" JAMg_model_15870.1 8 KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1 "Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis";"Starch and sucrose metabolism" JAMg_model_7416.1 1 Reactome: R-HSA-2468052 "Establishment of Sister Chromatid Cohesion" JAMg_model_17383.1 8 Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-113501 "Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Polymerase switching";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1" JAMg_model_6423.2 7 KEGG: 00680+3.1.3.11;KEGG: 00010+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00051+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00710+3.1.3.11;KEGG: 00030+3.1.3.11 "Methane metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway" JAMg_model_1718.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_13295.4 5 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-176407;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5687128 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"MAPK6/MAPK4 signaling" JAMg_model_18325.6 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" JAMg_model_8910.8 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" JAMg_model_4487.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" JAMg_model_7838.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" JAMg_model_10958.1 4 Reactome: R-HSA-1237112;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361 "Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" JAMg_model_1363.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_17536.1 3 MetaCyc: PWY-6854;Reactome: R-HSA-3299685;Reactome: R-HSA-3214847 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species";"HATs acetylate histones" JAMg_model_18181.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012 "L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency" JAMg_model_9606.1 11 Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-69166;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-174437;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554 "Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate from the C-strand";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" JAMg_model_19759.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" JAMg_model_2854.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" JAMg_model_3663.2 5 KEGG: 00240+2.7.1.21;MetaCyc: PWY-7199;Reactome: R-HSA-69205;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.21 "Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides salvage";"G1/S-Specific Transcription";"Pyrimidine salvage";"Drug metabolism - other enzymes" JAMg_model_16720.2 2 Reactome: R-HSA-2142691;Reactome: R-HSA-2142700 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)" JAMg_model_6151.2 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" JAMg_model_6212.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" JAMg_model_16619.1 3 MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367 "3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism" JAMg_model_13339.2 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" JAMg_model_19036.2 11 MetaCyc: PWY-6549;Reactome: R-HSA-71403;MetaCyc: PWY-5913;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6969;KEGG: 00720+1.1.1.42;MetaCyc: PWY-7254;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7124;MetaCyc: PWY-7268;MetaCyc: PWY-6728 "L-glutamine biosynthesis III";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"Glutathione metabolism";"Ethylene biosynthesis V (engineered)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Methylaspartate cycle" JAMg_model_8054.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68949 "Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Activation of the pre-replicative complex";"Orc1 removal from chromatin" JAMg_model_11895.7 5 MetaCyc: PWY-7159;MetaCyc: PWY-7766;Reactome: R-HSA-189451;KEGG: 00860+4.1.1.37;MetaCyc: PWY-5531 "3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme b biosynthesis IV (Gram-positive bacteria)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)" JAMg_model_11485.1 4 MetaCyc: PWY-6834;Reactome: R-HSA-351202;KEGG: 00330+4.1.1.50;KEGG: 00270+4.1.1.50 "Spermidine biosynthesis III";"Metabolism of polyamines";"Arginine and proline metabolism";"Cysteine and methionine metabolism" JAMg_model_9658.1 33 Reactome: R-HSA-68877;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-4085377;Reactome: R-HSA-141444;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-168276 "Mitotic Prometaphase";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"SUMOylation of SUMOylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways" JAMg_model_15441.9 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" JAMg_model_14694.2 5 Reactome: R-HSA-427413;Reactome: R-HSA-4655427;Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-5334118 "NoRC negatively regulates rRNA expression";"SUMOylation of DNA methylation proteins";"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"DNA methylation" JAMg_model_15508.4 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" JAMg_model_4348.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" JAMg_model_480.6 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" JAMg_model_8595.1 3 Reactome: R-HSA-159230;Reactome: R-HSA-73856;Reactome: R-HSA-77588 "Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" JAMg_model_5446.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_18739.1 12 Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-73762;Reactome: R-HSA-210744;Reactome: R-HSA-5250924;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-3214847 "NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"RNA Polymerase I Transcription Initiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"B-WICH complex positively regulates rRNA expression";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"HATs acetylate histones" JAMg_model_8855.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_20212.1 27 Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638 "Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins" JAMg_model_10149.2 3 Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007 "Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy" JAMg_model_8098.1 1 Reactome: R-HSA-163841 "Gamma carboxylation, hypusine formation and arylsulfatase activation" JAMg_model_1151.3 1 Reactome: R-HSA-8950505 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" JAMg_model_13166.1 3 Reactome: R-HSA-114608;Reactome: R-HSA-381426;Reactome: R-HSA-8957275 "Platelet degranulation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation" JAMg_model_4371.2 5 Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-164843;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571 "Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"2-LTR circle formation";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)" JAMg_model_4937.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" JAMg_model_19742.2 3 Reactome: R-HSA-1660661;Reactome: R-HSA-6798695;Reactome: R-HSA-9609523 "Sphingolipid de novo biosynthesis";"Neutrophil degranulation";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" JAMg_model_8153.1 3 KEGG: 00260+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3 "Glycine, serine and threonine metabolism";"Serine biosynthesis";"Methane metabolism" JAMg_model_6030.2 2 Reactome: R-HSA-1632852;Reactome: R-HSA-5689880 "Macroautophagy";"Ub-specific processing proteases" JAMg_model_2104.4 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_17314.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_11213.1 8 Reactome: R-HSA-6791226;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "Major pathway of rRNA processing in the nucleolus and cytosol";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" JAMg_model_11750.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" JAMg_model_1647.2 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_14251.1 1 Reactome: R-HSA-6798163 "Choline catabolism" JAMg_model_14030.1 5 Reactome: R-HSA-6798695;MetaCyc: PWY-7185;MetaCyc: PWY-7210;KEGG: 00230+3.6.1.6;KEGG: 00240+3.6.1.6 "Neutrophil degranulation";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Pyrimidine metabolism" JAMg_model_12764.3 16 Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827 "Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression" JAMg_model_1229.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_16249.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" JAMg_model_1964.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" JAMg_model_16208.4 5 Reactome: R-HSA-9029558;Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-2426168 "NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)" JAMg_model_4874.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" JAMg_model_1324.1 7 Reactome: R-HSA-1483148;KEGG: 00564+3.1.4.4;MetaCyc: PWY-3561;Reactome: R-HSA-1483166;MetaCyc: PWY-7039;Reactome: R-HSA-2029485;KEGG: 00565+3.1.4.4 "Synthesis of PG";"Glycerophospholipid metabolism";"Choline biosynthesis III";"Synthesis of PA";"Phosphatidate metabolism, as a signaling molecule";"Role of phospholipids in phagocytosis";"Ether lipid metabolism" JAMg_model_21161.5 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942 "Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition" JAMg_model_8686.2 2 MetaCyc: PWY-7802;MetaCyc: PWY-7799 "N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)" JAMg_model_18918.7 3 MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268 "Methylglyoxal degradation I";"Pyruvate metabolism";"Pyruvate metabolism" JAMg_model_11905.1 25 Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-380270;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-5617833;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-983189 "MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"HCMV Early Events";"Mitotic Prometaphase";"Kinesins" JAMg_model_19855.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" JAMg_model_10256.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" JAMg_model_18100.3 1 Reactome: R-HSA-1632852 "Macroautophagy" JAMg_model_7984.1 6 Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-176187 "Assembly of the pre-replicative complex";"Unwinding of DNA";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress" JAMg_model_1770.2 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" JAMg_model_21233.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" JAMg_model_18681.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" JAMg_model_8637.3 4 KEGG: 00513+2.4.1.261;Reactome: R-HSA-4720454;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.259+2.4.1.261 "Various types of N-glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis" JAMg_model_3789.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" JAMg_model_7691.2 2 MetaCyc: PWY-7511;Reactome: R-HSA-6783310 "Protein ubiquitination";"Fanconi Anemia Pathway" JAMg_model_7496.5 4 Reactome: R-HSA-983231;Reactome: R-HSA-2586552;Reactome: R-HSA-1170546;Reactome: R-HSA-982772 "Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin";"Prolactin receptor signaling";"Growth hormone receptor signaling" JAMg_model_13671.6 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_14650.1 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" JAMg_model_4089.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_5588.8 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" JAMg_model_1297.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" JAMg_model_1430.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" JAMg_model_20334.3 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" JAMg_model_1909.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" JAMg_model_9991.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" JAMg_model_2952.1 4 Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48 "Pyrimidine salvage";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes" JAMg_model_6649.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_18744.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport" JAMg_model_19550.4 56 Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978 "Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FCERI mediated NF-kB activation";"UCH proteinases";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"Orc1 removal from chromatin";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)" JAMg_model_1679.3 22 Reactome: R-HSA-5673000;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-389513;Reactome: R-HSA-5339716;Reactome: R-HSA-432142;Reactome: R-HSA-5663220;Reactome: R-HSA-6811558;Reactome: R-HSA-195253;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747;Reactome: R-HSA-2467813;Reactome: R-HSA-4641262;Reactome: R-HSA-68877;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-5675221;Reactome: R-HSA-5467337 "RAF activation";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"CTLA4 inhibitory signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"Platelet sensitization by LDL";"RHO GTPases Activate Formins";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Degradation of beta-catenin by the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Mitotic Prometaphase";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"APC truncation mutants have impaired AXIN binding" JAMg_model_10816.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_17317.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_14654.6 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" JAMg_model_5596.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_19483.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_20921.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" JAMg_model_21029.2 15 Reactome: R-HSA-195253;Reactome: R-HSA-5358749;Reactome: R-HSA-5467333;Reactome: R-HSA-5689896;Reactome: R-HSA-5467337;Reactome: R-HSA-111465;Reactome: R-HSA-5358752;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-3769402;Reactome: R-HSA-5358747;Reactome: R-HSA-4641262;Reactome: R-HSA-5467340;Reactome: R-HSA-5358751;Reactome: R-HSA-196299 "Degradation of beta-catenin by the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"Ovarian tumor domain proteases";"APC truncation mutants have impaired AXIN binding";"Apoptotic cleavage of cellular proteins";"T41 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex";"S33 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"AXIN missense mutants destabilize the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade" JAMg_model_10024.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_5587.7 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" JAMg_model_12785.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" JAMg_model_7404.3 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" JAMg_model_855.2 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" JAMg_model_15784.2 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" JAMg_model_13054.4 4 KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174;Reactome: R-HSA-1237112 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Methionine salvage pathway" JAMg_model_5588.10 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" JAMg_model_760.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" JAMg_model_4891.1 56 Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-69481 "Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"UCH proteinases";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"G2/M Checkpoints" JAMg_model_13767.1 6 Reactome: R-HSA-191273;Reactome: R-HSA-2426168;Reactome: R-HSA-446199;MetaCyc: PWY-7391;MetaCyc: PWY-922;KEGG: 00900+4.1.1.33 "Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Synthesis of Dolichyl-phosphate";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis" JAMg_model_10817.4 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_11074.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" JAMg_model_138.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" JAMg_model_1106.3 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_1731.1 5 Reactome: R-HSA-166208;Reactome: R-HSA-5674400;Reactome: R-HSA-165159;Reactome: R-HSA-3371571;Reactome: R-HSA-198323 "mTORC1-mediated signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signalling";"HSF1-dependent transactivation";"AKT phosphorylates targets in the cytosol" JAMg_model_6244.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" JAMg_model_14776.3 2 Reactome: R-HSA-8983711;Reactome: R-HSA-909733 "OAS antiviral response";"Interferon alpha/beta signaling" JAMg_model_18624.2 13 Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827 "Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression" JAMg_model_15725.3 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" JAMg_model_8666.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" JAMg_model_16141.1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72689 "Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Peptide chain elongation";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits" JAMg_model_14039.2 9 Reactome: R-HSA-416476;MetaCyc: PWY-6351;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;Reactome: R-HSA-112043 "G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"PLC beta mediated events" JAMg_model_13323.5 3 Reactome: R-HSA-110357;Reactome: R-HSA-110330;Reactome: R-HSA-110331 "Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine" JAMg_model_11737.2 1 Reactome: R-HSA-400253 "Circadian Clock" JAMg_model_9819.1 6 Reactome: R-HSA-6787450;Reactome: R-HSA-8868766;MetaCyc: PWY-6829;MetaCyc: PWY-7285;MetaCyc: PWY-7286;Reactome: R-HSA-6785470 "tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion";"Trna methylation (yeast)";"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA processing in the mitochondrion" JAMg_model_12337.1 26 Reactome: R-HSA-9617629;Reactome: R-HSA-381340;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-9013695;Reactome: R-HSA-1368082;Reactome: R-HSA-2122947;Reactome: R-HSA-5621575;Reactome: R-HSA-3134973;Reactome: R-HSA-1989781;Reactome: R-HSA-201722;Reactome: R-HSA-210744;Reactome: R-HSA-933541;Reactome: R-HSA-1912408;Reactome: R-HSA-3899300;Reactome: R-HSA-8941856;Reactome: R-HSA-1234158;Reactome: R-HSA-2894862;Reactome: R-HSA-8866907;Reactome: R-HSA-400253;Reactome: R-HSA-9018519;Reactome: R-HSA-918233;Reactome: R-HSA-5617472;Reactome: R-HSA-3371568;Reactome: R-HSA-9614657;Reactome: R-HSA-2644606 "Regulation of FOXO transcriptional activity by acetylation";"Transcriptional regulation of white adipocyte differentiation";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"PPARA activates gene expression";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"TRAF6 mediated IRF7 activation";"Pre-NOTCH Transcription and Translation";"SUMOylation of transcription cofactors";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activation of the TFAP2 (AP-2) family of transcription factors";"Circadian Clock";"Estrogen-dependent gene expression";"TRAF3-dependent IRF activation pathway";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Attenuation phase";"FOXO-mediated transcription of cell death genes";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" JAMg_model_21040.1 7 MetaCyc: PWY-5097;MetaCyc: PWY-2942;Reactome: R-HSA-389661;MetaCyc: PWY-8088;KEGG: 00300+4.3.3.7;MetaCyc: PWY-2941;KEGG: 00261+4.3.3.7 "L-lysine biosynthesis VI";"L-lysine biosynthesis III";"Glyoxylate metabolism and glycine degradation";"Dipicolinate biosynthesis";"Lysine biosynthesis";"L-lysine biosynthesis II";"Monobactam biosynthesis" JAMg_model_10954.1 4 MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163;MetaCyc: PWY-7494 "Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline catabolism";"Choline degradation IV" JAMg_model_4040.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" JAMg_model_13658.3 3 Reactome: R-HSA-6806664;MetaCyc: PWY-7999;KEGG: 00130+1.17.4.4 "Metabolism of vitamin K";"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis" JAMg_model_5258.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" JAMg_model_5646.1 2 KEGG: 00970+6.1.1.14;Reactome: R-HSA-2151201 "Aminoacyl-tRNA biosynthesis";"Transcriptional activation of mitochondrial biogenesis" JAMg_model_16433.1 5 Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-211976 "Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols" JAMg_model_19131.6 14 MetaCyc: PWY-8051;KEGG: 00565+3.1.3.4;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483213;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8053;MetaCyc: PWY-7782;Reactome: R-HSA-1483191;Reactome: R-HSA-75109;Reactome: R-HSA-4419969;MetaCyc: PWY-8052;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-6453 "Anandamide biosynthesis I";"Ether lipid metabolism";"Glycerolipid metabolism";"Synthesis of PE";"Sphingolipid metabolism";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Synthesis of PC";"Triglyceride biosynthesis";"Depolymerisation of the Nuclear Lamina";"2-arachidonoylglycerol biosynthesis";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis" JAMg_model_4772.1 2 Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" JAMg_model_16846.1 7 KEGG: 00052+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23 "Galactose metabolism";"Neutrophil degranulation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Glycosaminoglycan degradation" JAMg_model_9585.1 6 MetaCyc: PWY-6309;MetaCyc: PWY-5651;KEGG: 00380+1.14.13.9;Reactome: R-HSA-71240;MetaCyc: PWY-7765;MetaCyc: PWY-7717 "L-tryptophan degradation XI (mammalian, via kynurenine)";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Tryptophan metabolism";"Tryptophan catabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"3-hydroxy-4-methyl-anthranilate biosynthesis I" JAMg_model_6127.1 1 Reactome: R-HSA-6782861 "Synthesis of wybutosine at G37 of tRNA(Phe)" JAMg_model_800.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" JAMg_model_8553.2 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_18440.4 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" JAMg_model_7192.1 4 Reactome: R-HSA-1369062;Reactome: R-HSA-5688399;Reactome: R-HSA-5683826;Reactome: R-HSA-5683678 "ABC transporters in lipid homeostasis";"Defective ABCA3 causes pulmonary surfactant metabolism dysfunction 3 (SMDP3)";"Surfactant metabolism";"Defective ABCA3 causes pulmonary surfactant metabolism dysfunction type 3 (SMDP3)" JAMg_model_3662.3 16 Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Peptide chain elongation" JAMg_model_113.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_10489.3 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_3676.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" JAMg_model_2096.1 10 Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-3108214;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554 "Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"SUMOylation of DNA damage response and repair proteins";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" JAMg_model_3895.2 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" JAMg_model_12337.5 26 Reactome: R-HSA-918233;Reactome: R-HSA-9018519;Reactome: R-HSA-9614657;Reactome: R-HSA-2644606;Reactome: R-HSA-5617472;Reactome: R-HSA-3371568;Reactome: R-HSA-400253;Reactome: R-HSA-8866907;Reactome: R-HSA-2894862;Reactome: R-HSA-3899300;Reactome: R-HSA-1912408;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-201722;Reactome: R-HSA-210744;Reactome: R-HSA-933541;Reactome: R-HSA-3134973;Reactome: R-HSA-5621575;Reactome: R-HSA-1989781;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-3214847;Reactome: R-HSA-9617629 "TRAF3-dependent IRF activation pathway";"Estrogen-dependent gene expression";"FOXO-mediated transcription of cell death genes";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Attenuation phase";"Circadian Clock";"Activation of the TFAP2 (AP-2) family of transcription factors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SUMOylation of transcription cofactors";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"TRAF6 mediated IRF7 activation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"CD209 (DC-SIGN) signaling";"PPARA activates gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"HATs acetylate histones";"Regulation of FOXO transcriptional activity by acetylation" JAMg_model_21043.2 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" JAMg_model_18028.2 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" JAMg_model_13242.3 7 Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2 "Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism" JAMg_model_3317.1 6 Reactome: R-HSA-6811438;Reactome: R-HSA-416993;Reactome: R-HSA-6811434;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-204005 "Intra-Golgi traffic";"Trafficking of GluR2-containing AMPA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport" JAMg_model_17608.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_19296.2 3 Reactome: R-HSA-6804760;Reactome: R-HSA-191859;Reactome: R-HSA-3214858 "Regulation of TP53 Activity through Methylation";"snRNP Assembly";"RMTs methylate histone arginines" JAMg_model_3561.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7035;Reactome: R-HSA-75876 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs" JAMg_model_17598.2 11 Reactome: R-HSA-2426168;Reactome: R-HSA-3214858;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-6804114;Reactome: R-HSA-400253;Reactome: R-HSA-1368082 "Activation of gene expression by SREBF (SREBP)";"RMTs methylate histone arginines";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Estrogen-dependent gene expression";"PPARA activates gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Circadian Clock";"RORA activates gene expression" JAMg_model_18238.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_8371.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" JAMg_model_8477.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" JAMg_model_5205.2 7 Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-165159 "Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Macroautophagy";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"mTOR signalling" JAMg_model_15950.2 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" JAMg_model_17142.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" JAMg_model_20787.5 32 Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-168325;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-167238;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-75953;Reactome: R-HSA-167242;Reactome: R-HSA-73776;Reactome: R-HSA-6803529;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-72203;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-167158 "Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Viral Messenger RNA Synthesis";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Promoter Escape";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex" JAMg_model_3009.2 1 Reactome: R-HSA-6799198 "Complex I biogenesis" JAMg_model_9932.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_4541.9 7 Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518 "Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2" JAMg_model_20700.1 6 MetaCyc: PWY-6731;MetaCyc: PWY-5941;Reactome: R-HSA-70221;KEGG: 00500+2.4.1.1;MetaCyc: PWY-6737;MetaCyc: PWY-7238 "Starch degradation III";"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism";"Starch degradation V";"Sucrose biosynthesis II" JAMg_model_8725.5 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" JAMg_model_20584.1 17 Reactome: R-HSA-196780;MetaCyc: PWY-5789;Reactome: R-HSA-200425;KEGG: 00640+6.4.1.2;Reactome: R-HSA-163765;MetaCyc: PWY-6679;MetaCyc: PWY-5743;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-5966-1;Reactome: R-HSA-3371599;Reactome: R-HSA-2426168;KEGG: 00061+6.4.1.2;KEGG: 00254+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00720+6.4.1.2;MetaCyc: PWY-6722 "Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Carnitine metabolism";"Propanoate metabolism";"ChREBP activates metabolic gene expression";"Jadomycin biosynthesis";"3-hydroxypropanoate cycle";"Pyruvate metabolism";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Defective HLCS causes multiple carboxylase deficiency";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carbon fixation pathways in prokaryotes";"Candicidin biosynthesis" JAMg_model_619.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_5870.5 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_5266.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_17943.4 5 Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148 "RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" JAMg_model_974.2 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" JAMg_model_15911.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" JAMg_model_7440.1 1 Reactome: R-HSA-8876725 "Protein methylation" JAMg_model_20438.1 4 Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" JAMg_model_405.2 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" JAMg_model_20787.4 32 Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-168325;Reactome: R-HSA-6807505;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-167172;Reactome: R-HSA-8851708;Reactome: R-HSA-77075;Reactome: R-HSA-167242;Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-73776;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-72203;Reactome: R-HSA-6803529;Reactome: R-HSA-76042;Reactome: R-HSA-9018519;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167162;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Viral Messenger RNA Synthesis";"RNA polymerase II transcribes snRNA genes";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"Transcription of the HIV genome";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Processing of Capped Intron-Containing Pre-mRNA";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Estrogen-dependent gene expression";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Elongation" JAMg_model_3561.2 14 MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7619 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis" JAMg_model_11158.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" JAMg_model_20237.1 1 Reactome: R-HSA-5334118 "DNA methylation" JAMg_model_14765.1 3 Reactome: R-HSA-2980766;Reactome: R-HSA-4419969;Reactome: R-HSA-2995383 "Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation" JAMg_model_18043.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_6324.2 10 MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-5667;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.15 "Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism" JAMg_model_17580.5 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" JAMg_model_6137.1 33 Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-68877;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-168276 "SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Mitotic Prometaphase";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"snRNP Assembly";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways" JAMg_model_16039.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" JAMg_model_12569.2 13 MetaCyc: PWY-6728;MetaCyc: PWY-7384;MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5538;KEGG: 00720+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5913;MetaCyc: PWY-5392 "Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II" JAMg_model_14841.3 31 MetaCyc: PWY-7746;MetaCyc: PWY-5367;MetaCyc: PWYG-321;MetaCyc: PWY-7723;MetaCyc: PWY-5366;MetaCyc: PWY-7388;MetaCyc: PWY-7663;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-199220;MetaCyc: PWY-5994;MetaCyc: PWY-8047;MetaCyc: PWY-8049;MetaCyc: PWY-7858;MetaCyc: PWY-5971;MetaCyc: PWY-5142;Reactome: R-HSA-163765;Reactome: R-HSA-9029558;MetaCyc: PWY-5147;MetaCyc: PWY-5989;Reactome: R-HSA-75105;MetaCyc: PWY-5973;MetaCyc: PWY-7664;MetaCyc: PWY-5966-1;MetaCyc: PWY-4381;MetaCyc: PWY-6282;MetaCyc: PWY-6113;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6799;Reactome: R-HSA-2426168;MetaCyc: PWY-6519;MetaCyc: PWY-8012 "Mycobacterial sulfolipid biosynthesis";"Petroselinate biosynthesis";"";"Bacterial bioluminescence";"Palmitoleate biosynthesis II (plants and bacteria)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Bryostatin biosynthesis";"Pederin biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Acyl-[acyl-carrier protein] thioesterase pathway";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Oleate biosynthesis I (plants)";"Stearate biosynthesis II (bacteria and plants)";"Fatty acyl-CoA biosynthesis";"Cis-vaccenate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Superpathway of mycolate biosynthesis";"Biotin metabolism";"Fatty acid biosynthesis initiation (plant mitochondria)";"Activation of gene expression by SREBF (SREBP)";"8-amino-7-oxononanoate biosynthesis I";"Mupirocin biosynthesis" JAMg_model_1450.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis" JAMg_model_20866.4 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_13054.12 3 MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism" JAMg_model_13394.1 7 MetaCyc: PWY-7886;Reactome: R-HSA-1483213;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7818;MetaCyc: PWY-7782;Reactome: R-HSA-1483191;MetaCyc: PWY-3385 "Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PE";"Glycerophospholipid metabolism";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Plasmalogen biosynthesis";"Synthesis of PC";"Choline biosynthesis I" JAMg_model_7141.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" JAMg_model_20154.2 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_12919.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_10512.2 10 MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-6842;MetaCyc: PWY-7559;MetaCyc: PWY-8001;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2 "Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione metabolism";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism" JAMg_model_8758.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_14649.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" JAMg_model_11027.1 3 MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65;Reactome: R-HSA-1483213 "Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PE" JAMg_model_9473.3 8 MetaCyc: PWY-241;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-7115;MetaCyc: PWY-5789 "C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle" JAMg_model_20195.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" JAMg_model_12772.3 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" JAMg_model_17191.1 6 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-163560;Reactome: R-HSA-400253 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"Circadian Clock" JAMg_model_21056.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-936837 "Neutrophil degranulation";"Ion transport by P-type ATPases" JAMg_model_19953.1 4 Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex" JAMg_model_13561.1 5 Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-190873 "Formation of annular gap junctions";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation" JAMg_model_15583.1 19 Reactome: R-HSA-8964046;Reactome: R-HSA-8963901;Reactome: R-HSA-3000497;Reactome: R-HSA-8964041;Reactome: R-HSA-8866423;Reactome: R-HSA-8963888;Reactome: R-HSA-432142;Reactome: R-HSA-381426;Reactome: R-HSA-975634;Reactome: R-HSA-8964038;Reactome: R-HSA-5686938;Reactome: R-HSA-202733;Reactome: R-HSA-8957275;Reactome: R-HSA-3000480;Reactome: R-HSA-8856828;Reactome: R-HSA-8964026;Reactome: R-HSA-8856825;Reactome: R-HSA-3000471;Reactome: R-HSA-3000484 "VLDL clearance";"Chylomicron remodeling";"Scavenging by Class H Receptors";"LDL remodeling";"VLDL assembly";"Chylomicron assembly";"Platelet sensitization by LDL";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Retinoid metabolism and transport";"LDL clearance";"Regulation of TLR by endogenous ligand";"Cell surface interactions at the vascular wall";"Post-translational protein phosphorylation";"Scavenging by Class A Receptors";"Clathrin-mediated endocytosis";"Chylomicron clearance";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class B Receptors";"Scavenging by Class F Receptors" JAMg_model_20225.1 1 Reactome: R-HSA-191859 "snRNP Assembly" JAMg_model_13723.1 3 KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067;Reactome: R-HSA-3322077 "Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis" JAMg_model_15508.7 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" JAMg_model_16232.5 4 Reactome: R-HSA-156581;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;MetaCyc: PWY-5912 "Methylation";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis" JAMg_model_20499.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9615710 "Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy" JAMg_model_6830.1 10 KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;MetaCyc: PWY-5497;MetaCyc: PWY-1722;Reactome: R-HSA-196757;MetaCyc: PWY-5030;MetaCyc: PWY-7909;MetaCyc: PWY-6613;MetaCyc: PWY-3841 "One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Folate transformations I";"Purine nucleobases degradation II (anaerobic)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Metabolism of folate and pterines";"L-histidine degradation III";"Formaldehyde oxidation VII (THF pathway)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations II (plants)" JAMg_model_11169.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" JAMg_model_5030.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" JAMg_model_19084.4 5 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination" JAMg_model_11882.4 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" JAMg_model_18325.2 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" JAMg_model_11650.2 1 Reactome: R-HSA-71262 "Carnitine synthesis" JAMg_model_14607.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733 "Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis" JAMg_model_2826.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" JAMg_model_19885.1 2 Reactome: R-HSA-1236974;Reactome: R-HSA-1799339 "ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane" JAMg_model_8131.2 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" JAMg_model_15216.2 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" JAMg_model_18330.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_12303.2 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_11092.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_1168.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-6793080 "Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion" JAMg_model_12148.3 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" JAMg_model_10298.1 3 KEGG: 00643+1.13.11.5;Reactome: R-HSA-8963684;KEGG: 00350+1.13.11.5 "Styrene degradation";"Tyrosine catabolism";"Tyrosine metabolism" JAMg_model_14760.2 2 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Synthesis of PG";"Synthesis of PA" JAMg_model_19272.4 2 Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22 "Histidine catabolism";"Histidine metabolism" JAMg_model_4874.2 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" JAMg_model_14869.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_8550.1 14 MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7725 "Juniperonate biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)" JAMg_model_13852.1 8 MetaCyc: PWY-5723;KEGG: 00710+5.3.1.6;KEGG: 00051+5.3.1.6;Reactome: R-HSA-71336;KEGG: 00030+5.3.1.6;Reactome: R-HSA-5659996;MetaCyc: PWY-1861;Reactome: R-HSA-6791461 "Rubisco shunt";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Pentose phosphate pathway";"RPIA deficiency: failed conversion of R5P to RU5P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"RPIA deficiency: failed conversion of RU5P to R5P" JAMg_model_17834.1 3 MetaCyc: PWY-6689;Reactome: R-HSA-6784531;MetaCyc: PWY-7803 "Trna splicing I";"tRNA processing in the nucleus";"Trna splicing II" JAMg_model_21047.4 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" JAMg_model_6067.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" JAMg_model_19469.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" JAMg_model_1647.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_907.13 8 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-190873;Reactome: R-HSA-432720;Reactome: R-HSA-3928665;Reactome: R-HSA-5099900;Reactome: R-HSA-5140745 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"Gap junction degradation";"Lysosome Vesicle Biogenesis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2" JAMg_model_21354.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" JAMg_model_2500.1 3 Reactome: R-HSA-2173791;Reactome: R-HSA-420029;Reactome: R-HSA-4608870 "TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Tight junction interactions";"Asymmetric localization of PCP proteins" JAMg_model_855.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" JAMg_model_10191.2 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" JAMg_model_14338.2 5 Reactome: R-HSA-2022857;Reactome: R-HSA-2206305;KEGG: 00531+3.1.6.14;Reactome: R-HSA-432720;Reactome: R-HSA-6798695 "Keratan sulfate degradation";"MPS IIID - Sanfilippo syndrome D";"Glycosaminoglycan degradation";"Lysosome Vesicle Biogenesis";"Neutrophil degranulation" JAMg_model_7435.2 9 Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-73779 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" JAMg_model_12703.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" JAMg_model_18910.4 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" JAMg_model_13339.5 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" JAMg_model_7587.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" JAMg_model_8637.2 4 Reactome: R-HSA-4720454;KEGG: 00513+2.4.1.261;KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-446193 "Defective ALG9 causes ALG9-CDG (CDG-1l)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" JAMg_model_14445.4 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" JAMg_model_9200.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" JAMg_model_2885.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" JAMg_model_9329.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649 "Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation" JAMg_model_13313.2 3 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" JAMg_model_16306.1 5 KEGG: 00270+4.2.1.109;MetaCyc: PWY-4361;Reactome: R-HSA-9627069;Reactome: R-HSA-1237112;Reactome: R-HSA-111458 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Regulation of the apoptosome activity";"Methionine salvage pathway";"Formation of apoptosome" JAMg_model_12776.2 3 Reactome: R-HSA-6798695;Reactome: R-HSA-2024096;Reactome: R-HSA-2206291 "Neutrophil degranulation";"HS-GAG degradation";"MPS IIIC - Sanfilippo syndrome C" JAMg_model_1523.9 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8949613 "Mitochondrial protein import";"Cristae formation" JAMg_model_17025.1 57 Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-6798695;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-180585 "Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"Neutrophil degranulation";"UCH proteinases";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G" JAMg_model_639.4 24 Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-9648025;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467 "Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"HCMV Early Events";"Mitotic Prometaphase";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"EML4 and NUDC in mitotic spindle formation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs" JAMg_model_11706.1 17 Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Viral mRNA Translation" JAMg_model_11278.1 3 Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification" JAMg_model_13394.2 7 Reactome: R-HSA-1483213;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7886;MetaCyc: PWY-7818;MetaCyc: PWY-7782;Reactome: R-HSA-1483191;MetaCyc: PWY-3385 "Synthesis of PE";"Glycerophospholipid metabolism";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Plasmalogen biosynthesis";"Synthesis of PC";"Choline biosynthesis I" JAMg_model_12579.2 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" JAMg_model_10124.6 6 KEGG: 00630+4.2.1.3;Reactome: R-HSA-1268020;KEGG: 00720+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;Reactome: R-HSA-71403 "Glyoxylate and dicarboxylate metabolism";"Mitochondrial protein import";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Citric acid cycle (TCA cycle)" JAMg_model_5876.3 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_17161.1 5 KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317 "Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Stachyose degradation";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)" JAMg_model_1040.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" JAMg_model_20447.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" JAMg_model_1310.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" JAMg_model_21049.3 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" JAMg_model_13715.5 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_20782.1 57 Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-5678895;Reactome: R-HSA-6798695;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-174113;Reactome: R-HSA-202424 "CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"FCERI mediated NF-kB activation";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"Defective CFTR causes cystic fibrosis";"Neutrophil degranulation";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of DVL";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI2 by the proteasome";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"Orc1 removal from chromatin";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling" JAMg_model_3715.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_2132.5 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" JAMg_model_20214.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_19224.3 1 Reactome: R-HSA-5676934 "Protein repair" JAMg_model_18883.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" JAMg_model_11544.1 5 Reactome: R-HSA-8849471;Reactome: R-HSA-5658442;Reactome: R-HSA-5218921;Reactome: R-HSA-186763;Reactome: R-HSA-3928662 "PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Regulation of RAS by GAPs";"VEGFR2 mediated cell proliferation";"Downstream signal transduction";"EPHB-mediated forward signaling" JAMg_model_6805.2 1 Reactome: R-HSA-5635838 "Activation of SMO" JAMg_model_5022.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" JAMg_model_5687.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" JAMg_model_16740.2 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" JAMg_model_20780.2 57 Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-6798695;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-180534 "FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"Neutrophil degranulation";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"FCERI mediated NF-kB activation";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4" JAMg_model_13561.2 5 Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-196025 "Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Formation of annular gap junctions" JAMg_model_12508.6 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" JAMg_model_6601.4 1 Reactome: R-HSA-189200 "Cellular hexose transport" JAMg_model_5878.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_20577.2 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_5262.3 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" JAMg_model_1394.1 26 Reactome: R-HSA-8955332;Reactome: R-HSA-389977;Reactome: R-HSA-6811434;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-9609736;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-389960;Reactome: R-HSA-983189;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-5617833 "Carboxyterminal post-translational modifications of tubulin";"Post-chaperonin tubulin folding pathway";"COPI-dependent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Aggrephagy";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"HCMV Early Events";"Mitotic Prometaphase";"Assembly and cell surface presentation of NMDA receptors";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Formation of tubulin folding intermediates by CCT/TriC";"Kinesins";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Cilium Assembly" JAMg_model_1398.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" JAMg_model_17227.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" JAMg_model_1641.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" JAMg_model_7893.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" JAMg_model_5403.3 13 Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Peptide chain elongation" JAMg_model_14483.1 5 Reactome: R-HSA-8939243;Reactome: R-HSA-3247509;Reactome: R-HSA-201722;Reactome: R-HSA-3214858;Reactome: R-HSA-1266695 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines";"Interleukin-7 signaling" JAMg_model_185.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis" JAMg_model_4998.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" JAMg_model_148.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_258.2 5 Reactome: R-HSA-5610787;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780 "Hedgehog 'off' state";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome" JAMg_model_20300.2 8 Reactome: R-HSA-8854518;Reactome: R-HSA-5689880;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380284 "AURKA Activation by TPX2";"Ub-specific processing proteases";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome" JAMg_model_15828.1 6 Reactome: R-HSA-2173796;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-5626467 "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"RHO GTPases activate IQGAPs" JAMg_model_17161.6 5 MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6 "D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Galactose metabolism";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism" JAMg_model_9515.3 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_20372.2 3 Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" JAMg_model_8698.4 22 Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7728;MetaCyc: PWY-8041;MetaCyc: PWY-7592;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-5353;MetaCyc: PWY-6958;MetaCyc: PWY-7606;MetaCyc: PWY-7726;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7727;MetaCyc: PWY-7049;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-6433;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7053 "Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Docosahexaenoate biosynthesis I (lower eukaryotes)" JAMg_model_15126.4 13 Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827 "Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Peptide chain elongation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression" JAMg_model_12130.3 24 Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434 "Separation of Sister Chromatids";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"Mitotic Prometaphase";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_7092.2 5 MetaCyc: PWY-4981;MetaCyc: PWY-6344;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539 "L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism" JAMg_model_15126.3 13 Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Viral mRNA Translation" JAMg_model_10817.2 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_236.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5690338 "ABC-family proteins mediated transport";"Defective ABCC6 causes pseudoxanthoma elasticum (PXE)" JAMg_model_11282.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" JAMg_model_8759.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_9479.1 5 Reactome: R-HSA-5632684;Reactome: R-HSA-5635838;Reactome: R-HSA-5610787;Reactome: R-HSA-5620922;Reactome: R-HSA-373080 "Hedgehog 'on' state";"Activation of SMO";"Hedgehog 'off' state";"BBSome-mediated cargo-targeting to cilium";"Class B/2 (Secretin family receptors)" JAMg_model_11907.4 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" JAMg_model_2919.1 2 KEGG: 00514+2.4.1.221;Reactome: R-HSA-1912399 "Other types of O-glycan biosynthesis";"Pre-NOTCH Processing in the Endoplasmic Reticulum" JAMg_model_10918.2 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" JAMg_model_13323.2 3 Reactome: R-HSA-110357;Reactome: R-HSA-110331;Reactome: R-HSA-110330 "Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine" JAMg_model_9797.1 14 Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-191273;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Cholesterol biosynthesis";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane" JAMg_model_4574.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation" JAMg_model_16817.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_4891.2 56 Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-983168 "Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"FCERI mediated NF-kB activation";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_11650.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" JAMg_model_12880.3 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" JAMg_model_4046.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" JAMg_model_11541.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359 "Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels" JAMg_model_19141.4 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" JAMg_model_15506.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" JAMg_model_4248.2 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" JAMg_model_8159.1 12 MetaCyc: PWY-1861;MetaCyc: PWY-6142;Reactome: R-HSA-70171;KEGG: 00030+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00051+4.1.2.13;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00710+4.1.2.13;KEGG: 00680+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-5484 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)" JAMg_model_3237.1 13 Reactome: R-HSA-416993;Reactome: R-HSA-8866427;Reactome: R-HSA-2132295;Reactome: R-HSA-167590;Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-177504;Reactome: R-HSA-3928665;Reactome: R-HSA-8964038;Reactome: R-HSA-182218;Reactome: R-HSA-8856825;Reactome: R-HSA-437239;Reactome: R-HSA-8856828 "Trafficking of GluR2-containing AMPA receptors";"VLDLR internalisation and degradation";"MHC class II antigen presentation";"Nef Mediated CD4 Down-regulation";"WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Retrograde neurotrophin signalling";"EPH-ephrin mediated repulsion of cells";"LDL clearance";"Nef Mediated CD8 Down-regulation";"Cargo recognition for clathrin-mediated endocytosis";"Recycling pathway of L1";"Clathrin-mediated endocytosis" JAMg_model_2755.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" JAMg_model_15097.6 8 Reactome: R-HSA-167590;Reactome: R-HSA-1222556;Reactome: R-HSA-9636467;Reactome: R-HSA-182218;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "Nef Mediated CD4 Down-regulation";"ROS and RNS production in phagocytes";"Blockage of phagosome acidification";"Nef Mediated CD8 Down-regulation";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling" JAMg_model_1039.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" JAMg_model_14870.3 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" JAMg_model_10745.2 5 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" JAMg_model_6292.3 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" JAMg_model_9719.2 2 KEGG: 00230+4.6.1.1;Reactome: R-HSA-196819 "Purine metabolism";"Vitamin B1 (thiamin) metabolism" JAMg_model_17269.4 3 MetaCyc: PWY-8106;Reactome: R-HSA-6782315;MetaCyc: PWY-6700 "Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)" JAMg_model_7189.2 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" JAMg_model_14260.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" JAMg_model_5047.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" JAMg_model_5870.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_7355.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_6466.2 26 Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-389960;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-389977;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332 "Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"Formation of tubulin folding intermediates by CCT/TriC";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"Mitotic Prometaphase";"HCMV Early Events";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"Aggrephagy";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Post-chaperonin tubulin folding pathway";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin" JAMg_model_8268.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" JAMg_model_18567.2 7 MetaCyc: PWY-7456;MetaCyc: PWY-5659;KEGG: 00051+5.4.2.8;MetaCyc: PWY-7586;MetaCyc: PWY-882;KEGG: 00520+5.4.2.8;Reactome: R-HSA-446205 "Beta-(1,4)-mannan degradation";"GDP-mannose biosynthesis";"Fructose and mannose metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose" JAMg_model_6050.1 3 KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403;MetaCyc: PWY-7942 "Glutathione metabolism";"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism" JAMg_model_1520.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" JAMg_model_16399.3 4 Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" JAMg_model_12942.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_18918.6 3 Reactome: R-HSA-70268;MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5 "Pyruvate metabolism";"Methylglyoxal degradation I";"Pyruvate metabolism" JAMg_model_10745.1 5 Reactome: R-HSA-72165;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA Splicing - Minor Pathway";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" JAMg_model_2059.2 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" JAMg_model_13649.3 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" JAMg_model_10892.2 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" JAMg_model_859.3 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" JAMg_model_1294.2 56 Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-8951664 "Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation" JAMg_model_8298.12 4 Reactome: R-HSA-1912420;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" JAMg_model_21162.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_8115.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_18377.1 5 Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-3769402 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Deactivation of the beta-catenin transactivating complex" JAMg_model_15513.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" JAMg_model_3589.1 5 Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436 "COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Neutrophil degranulation";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic" JAMg_model_19874.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_2157.4 1 Reactome: R-HSA-189451 "Heme biosynthesis" JAMg_model_16392.1 6 Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-3769402;Reactome: R-HSA-3214841;Reactome: R-HSA-8951664;Reactome: R-HSA-201722 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deactivation of the beta-catenin transactivating complex";"PKMTs methylate histone lysines";"Neddylation";"Formation of the beta-catenin:TCF transactivating complex" JAMg_model_20788.2 9 Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-75953 "HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation" JAMg_model_21344.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" JAMg_model_17278.1 11 Reactome: R-HSA-1660516;MetaCyc: PWY-6352;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660499;Reactome: R-HSA-5668599;Reactome: R-HSA-1660517;Reactome: R-HSA-1660514;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1632852;Reactome: R-HSA-109704;Reactome: R-HSA-168138 "Synthesis of PIPs at the early endosome membrane";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"RHO GTPases Activate NADPH Oxidases";"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Inositol phosphate metabolism";"Macroautophagy";"PI3K Cascade";"Toll Like Receptor 9 (TLR9) Cascade" JAMg_model_15276.1 57 Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-532668;Reactome: R-HSA-174154;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-8939902 "Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI2 by the proteasome";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity" JAMg_model_10017.1 1 Reactome: R-HSA-8874211 "CREB3 factors activate genes" JAMg_model_20984.3 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308 "NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening" JAMg_model_19134.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" JAMg_model_4381.3 5 Reactome: R-HSA-6782135;Reactome: R-HSA-6783310;Reactome: R-HSA-5696400;Reactome: R-HSA-5685938;Reactome: R-HSA-5696395 "Dual incision in TC-NER";"Fanconi Anemia Pathway";"Dual Incision in GG-NER";"HDR through Single Strand Annealing (SSA)";"Formation of Incision Complex in GG-NER" JAMg_model_750.3 1 Reactome: R-HSA-189200 "Cellular hexose transport" JAMg_model_1835.1 1 Reactome: R-HSA-3295583 "TRP channels" JAMg_model_18047.3 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" JAMg_model_7281.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_11737.6 1 Reactome: R-HSA-400253 "Circadian Clock" JAMg_model_6807.7 5 KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3;Reactome: R-HSA-917937 "Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Iron uptake and transport" JAMg_model_17161.3 5 MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-6317 "D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)" JAMg_model_3549.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" JAMg_model_16028.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_13153.1 12 Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-1251985;Reactome: R-HSA-977225;Reactome: R-HSA-193692;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-3928665;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-2644606 "Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"Nuclear signaling by ERBB4";"Amyloid fiber formation";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" JAMg_model_13397.2 7 KEGG: 00564+2.7.1.32+2.7.1.82;Reactome: R-HSA-1483213;MetaCyc: PWY-7818;MetaCyc: PWY-7886;Reactome: R-HSA-1483191;MetaCyc: PWY-7782;MetaCyc: PWY-3385 "Glycerophospholipid metabolism";"Synthesis of PE";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PC";"Plasmalogen biosynthesis";"Choline biosynthesis I" JAMg_model_1489.3 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" JAMg_model_5973.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" JAMg_model_12850.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" JAMg_model_13589.1 3 MetaCyc: PWY-7833;Reactome: R-HSA-9033807;MetaCyc: PWY-7831 "Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide" JAMg_model_3222.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" JAMg_model_20789.1 57 Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-6798695;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-174084 "NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"Orc1 removal from chromatin";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"UCH proteinases";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"Neutrophil degranulation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C" JAMg_model_11645.2 5 Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling" JAMg_model_4165.3 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" JAMg_model_17873.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" JAMg_model_1138.1 10 MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-7559;MetaCyc: PWY-6842;MetaCyc: PWY-8001;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2 "Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione metabolism";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism" JAMg_model_15597.2 40 Reactome: R-HSA-167238;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-8851708;Reactome: R-HSA-5617472;Reactome: R-HSA-167172;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-203927;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-168325;Reactome: R-HSA-6781827;Reactome: R-HSA-5578749;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-6803529;Reactome: R-HSA-5601884;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-72203;Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-75953;Reactome: R-HSA-167242;Reactome: R-HSA-73776;Reactome: R-HSA-6782135 "Pausing and recovery of Tat-mediated HIV elongation";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"Signaling by FGFR2 IIIa TM";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcription of the HIV genome";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"MicroRNA (miRNA) biogenesis";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Viral Messenger RNA Synthesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcriptional regulation by small RNAs";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"FGFR2 alternative splicing";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Capped Intron-Containing Pre-mRNA";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Promoter Escape";"Dual incision in TC-NER" JAMg_model_20334.11 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" JAMg_model_19296.1 3 Reactome: R-HSA-191859;Reactome: R-HSA-6804760;Reactome: R-HSA-3214858 "snRNP Assembly";"Regulation of TP53 Activity through Methylation";"RMTs methylate histone arginines" JAMg_model_19798.1 4 MetaCyc: PWY-5188;KEGG: 00860+2.5.1.61;MetaCyc: PWY-5189;Reactome: R-HSA-189451 "Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis" JAMg_model_15612.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" JAMg_model_6121.1 12 Reactome: R-HSA-5628897;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9619483;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04926+2.7.11.1 "TP53 Regulates Metabolic Genes";"Human cytomegalovirus infection";"Activation of AMPK downstream of NMDARs";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Macroautophagy";"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection";"Thermogenesis";"Energy dependent regulation of mTOR by LKB1-AMPK";"Relaxin signaling pathway" JAMg_model_12847.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7601 "(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" JAMg_model_20275.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" JAMg_model_4397.3 7 Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-380972 "TP53 Regulates Metabolic Genes";"mTOR signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK" JAMg_model_5030.2 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" JAMg_model_10489.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_9771.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" JAMg_model_13545.4 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" JAMg_model_12051.1 1 Reactome: R-HSA-5668599 "RHO GTPases Activate NADPH Oxidases" JAMg_model_11442.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" JAMg_model_8094.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" JAMg_model_17166.2 5 KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00720+4.2.1.3 "Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Iron uptake and transport";"Carbon fixation pathways in prokaryotes" JAMg_model_602.3 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression" JAMg_model_579.2 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" JAMg_model_12573.5 18 KEGG: 00720+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-5913;MetaCyc: PWY-1622;KEGG: 00710+1.1.1.37;MetaCyc: PWY-5690;Reactome: R-HSA-70263;MetaCyc: PWY-7383;MetaCyc: PWY-561;KEGG: 00020+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-8086;KEGG: 00630+1.1.1.37;MetaCyc: PWY-7115;KEGG: 00620+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-6728 "Carbon fixation pathways in prokaryotes";"Cysteine and methionine metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Formaldehyde assimilation I (serine pathway)";"Carbon fixation in photosynthetic organisms";"TCA cycle II (plants and fungi)";"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Glyoxylate and dicarboxylate metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Pyruvate metabolism";"Methane metabolism";"Methylaspartate cycle" JAMg_model_4794.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway" JAMg_model_8376.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" JAMg_model_1851.1 1 Reactome: R-HSA-427601 "Multifunctional anion exchangers" JAMg_model_9899.2 13 Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane" JAMg_model_15864.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" JAMg_model_1676.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" JAMg_model_2017.2 5 Reactome: R-HSA-197264;Reactome: R-HSA-1368108;MetaCyc: PWY-5381;Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21 "Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism" JAMg_model_985.1 3 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15;Reactome: R-HSA-5628897 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism";"TP53 Regulates Metabolic Genes" JAMg_model_15658.1 1 MetaCyc: PWY-6938 "NADH repair" JAMg_model_11352.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" JAMg_model_9194.3 6 KEGG: 00670+2.1.2.3;Reactome: R-HSA-73817;KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-7234;MetaCyc: PWY-6123;MetaCyc: PWY-6124 "One carbon pool by folate";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II" JAMg_model_17278.2 11 Reactome: R-HSA-1660517;Reactome: R-HSA-1632852;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1660514;Reactome: R-HSA-109704;Reactome: R-HSA-168138;Reactome: R-HSA-1660516;MetaCyc: PWY-6352;Reactome: R-HSA-1660499;KEGG: 04070+2.7.1.137;Reactome: R-HSA-5668599 "Synthesis of PIPs at the late endosome membrane";"Macroautophagy";"Inositol phosphate metabolism";"Synthesis of PIPs at the Golgi membrane";"PI3K Cascade";"Toll Like Receptor 9 (TLR9) Cascade";"Synthesis of PIPs at the early endosome membrane";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"RHO GTPases Activate NADPH Oxidases" JAMg_model_2428.1 24 Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-983189 "MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Mitotic Prometaphase";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"Kinesins" JAMg_model_3496.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" JAMg_model_3205.1 24 Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"Kinesins";"HCMV Early Events";"Mitotic Prometaphase";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion" JAMg_model_19463.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" JAMg_model_13658.1 3 KEGG: 00130+1.17.4.4;MetaCyc: PWY-7999;Reactome: R-HSA-6806664 "Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle";"Metabolism of vitamin K" JAMg_model_480.3 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" JAMg_model_14359.1 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_3743.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_997.3 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" JAMg_model_15074.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" JAMg_model_907.1 8 Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-432720;Reactome: R-HSA-190873;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-5099900 "Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4" JAMg_model_4090.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" JAMg_model_13276.1 5 KEGG: 00640+1.2.4.4;MetaCyc: PWY-5046;KEGG: 00280+1.2.4.4;Reactome: R-HSA-70895;Reactome: R-HSA-389661 "Propanoate metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"Glyoxylate metabolism and glycine degradation" JAMg_model_15267.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" JAMg_model_21086.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" JAMg_model_18210.2 5 MetaCyc: PWY-7560;MetaCyc: PWY-6891;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6892;KEGG: 00730+2.2.1.7 "Methylerythritol phosphate pathway II";"Thiazole biosynthesis II (aerobic bacteria)";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiamine metabolism" JAMg_model_18710.1 3 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.14;Reactome: R-HSA-379726 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" JAMg_model_4446.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" JAMg_model_15390.1 33 Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-4085377;Reactome: R-HSA-141444;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"SUMOylation of SUMOylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" JAMg_model_21290.1 2 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis" JAMg_model_20215.1 3 Reactome: R-HSA-2024101;Reactome: R-HSA-2024096;Reactome: R-HSA-2206302 "CS/DS degradation";"HS-GAG degradation";"MPS I - Hurler syndrome" JAMg_model_7995.2 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" JAMg_model_12130.1 24 Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467 "Mitotic Prometaphase";"HCMV Early Events";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs" JAMg_model_21274.1 4 Reactome: R-HSA-6802952;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-1632852 "Signaling by BRAF and RAF fusions";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Macroautophagy" JAMg_model_10797.6 1 Reactome: R-HSA-5676934 "Protein repair" JAMg_model_19162.8 1 Reactome: R-HSA-163560 "Triglyceride catabolism" JAMg_model_13389.1 7 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection" JAMg_model_20334.8 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" JAMg_model_11954.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" JAMg_model_990.2 14 Reactome: R-HSA-196757;KEGG: 00460+2.1.2.1;MetaCyc: PWY-3841;KEGG: 00630+2.1.2.1;KEGG: 00680+2.1.2.1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-1622;MetaCyc: PWY-5497;MetaCyc: PWY-2201;KEGG: 00260+2.1.2.1;MetaCyc: PWY-2161;MetaCyc: PWY-3661;MetaCyc: PWY-181;MetaCyc: PWY-3661-1 "Metabolism of folate and pterines";"Cyanoamino acid metabolism";"Folate transformations II (plants)";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism";"One carbon pool by folate";"Formaldehyde assimilation I (serine pathway)";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"Glycine, serine and threonine metabolism";"Folate polyglutamylation";"Glycine betaine degradation I";"Photorespiration ";"Glycine betaine degradation II (mammalian)" JAMg_model_12635.2 3 Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism";"Pentose phosphate pathway" JAMg_model_16074.1 10 KEGG: 00564+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-7587 "Glycerophospholipid metabolism";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)" JAMg_model_8875.5 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_3854.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" JAMg_model_5588.4 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" JAMg_model_8096.3 5 Reactome: R-HSA-168315;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-77595 "Inhibition of Host mRNA Processing and RNA Silencing";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs" JAMg_model_3428.1 4 Reactome: R-HSA-975871;Reactome: R-HSA-6799198;Reactome: R-HSA-975138;Reactome: R-HSA-166058 "MyD88 cascade initiated on plasma membrane";"Complex I biogenesis";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane" JAMg_model_20291.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" JAMg_model_3113.1 4 Reactome: R-HSA-4551295;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.131;KEGG: 00510+2.4.1.131 "Defective ALG11 causes ALG11-CDG (CDG-1p)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis" JAMg_model_19134.2 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" JAMg_model_12391.3 7 MetaCyc: PWY-7625;MetaCyc: PWY-6351;KEGG: 00562+2.7.8.11;KEGG: 04070+2.7.8.11;KEGG: 00564+2.7.8.11;MetaCyc: PWY-6352;Reactome: R-HSA-1483226 "Phosphatidylinositol biosynthesis II (eukaryotes)";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"3-phosphoinositide biosynthesis";"Synthesis of PI" JAMg_model_53.1 7 KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;MetaCyc: PWY-8052;MetaCyc: PWY-7039 "Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule" JAMg_model_7553.1 6 Reactome: R-HSA-390247;Reactome: R-HSA-9033500;Reactome: R-HSA-9033241;Reactome: R-HSA-193368;Reactome: R-HSA-389887;Reactome: R-HSA-2046106 "Beta-oxidation of very long chain fatty acids";"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import";"Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol";"Beta-oxidation of pristanoyl-CoA";"alpha-linolenic acid (ALA) metabolism" JAMg_model_11645.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288 "Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1" JAMg_model_6333.3 10 MetaCyc: PWY-5892;MetaCyc: PWY-5844;MetaCyc: PWY-5895;MetaCyc: PWY-5891;KEGG: 00130+2.1.1.163;Reactome: R-HSA-2142789;MetaCyc: PWY-7996;MetaCyc: PWY-5839;MetaCyc: PWY-5849;MetaCyc: PWY-5890 "Menaquinol-12 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-11 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-7 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-10 biosynthesis" JAMg_model_20019.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" JAMg_model_1524.2 5 Reactome: R-HSA-350054;Reactome: R-HSA-5083630;Reactome: R-HSA-1912408;Reactome: R-HSA-1912420;Reactome: R-HSA-1912399 "Notch-HLH transcription pathway";"Defective LFNG causes SCDO3";"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Processing in the Endoplasmic Reticulum" JAMg_model_12635.3 3 Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism" JAMg_model_11821.1 20 Reactome: R-HSA-5696397;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-6782210;Reactome: R-HSA-176187;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-6804756;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-174411 "Gap-filling DNA repair synthesis and ligation in GG-NER";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of ATR in response to replication stress";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Dual incision in TC-NER";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere" JAMg_model_11657.2 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" JAMg_model_7790.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" JAMg_model_17677.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_11395.1 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" JAMg_model_12343.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_15135.2 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" JAMg_model_16324.1 3 Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification" JAMg_model_10492.1 5 Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-9630222;Reactome: R-HSA-9630221 "Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective NTHL1 substrate binding";"Defective NTHL1 substrate processing" JAMg_model_8643.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" JAMg_model_14039.1 9 MetaCyc: PWY-6351;MetaCyc: PWY-8052;Reactome: R-HSA-416476;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;Reactome: R-HSA-112043;KEGG: 04070+3.1.4.11 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"PLC beta mediated events";"Phosphatidylinositol signaling system" JAMg_model_1102.3 2 Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58 "Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis" JAMg_model_3202.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" JAMg_model_18534.1 5 Reactome: R-HSA-3247509;Reactome: R-HSA-8939243;Reactome: R-HSA-201722;Reactome: R-HSA-1266695;Reactome: R-HSA-3214858 "Chromatin modifying enzymes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling";"RMTs methylate histone arginines" JAMg_model_11657.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" JAMg_model_15609.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_7111.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis" JAMg_model_8698.3 22 MetaCyc: PWY-7619;MetaCyc: PWY-7728;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7592;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7727;MetaCyc: PWY-5353;MetaCyc: PWY-7606;MetaCyc: PWY-6958;MetaCyc: PWY-7726;MetaCyc: PWY-7035;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7053;MetaCyc: PWY-5080;MetaCyc: PWY-7049;MetaCyc: PWY-6433;MetaCyc: PWY-7602 "Juniperonate biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" JAMg_model_20735.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" JAMg_model_8550.2 14 MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-8041 "Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis" JAMg_model_14662.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" JAMg_model_14202.1 4 KEGG: 00250+6.3.4.4;Reactome: R-HSA-73817;KEGG: 00230+6.3.4.4;MetaCyc: PWY-7219 "Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis" JAMg_model_13697.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" JAMg_model_19789.1 2 Reactome: R-HSA-1660499;Reactome: R-HSA-1632852 "Synthesis of PIPs at the plasma membrane";"Macroautophagy" JAMg_model_13645.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" JAMg_model_4772.3 2 Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" JAMg_model_1293.3 6 MetaCyc: PWY-8004;MetaCyc: PWY-1622;KEGG: 00010+5.4.2.11;KEGG: 00260+5.4.2.11;KEGG: 00680+5.4.2.11;MetaCyc: PWY-5484 "Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)";"Glycolysis / Gluconeogenesis";"Glycine, serine and threonine metabolism";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)" JAMg_model_20489.3 11 Reactome: R-HSA-3371378;Reactome: R-HSA-5218900;Reactome: R-HSA-9013957;Reactome: R-HSA-140534;Reactome: R-HSA-75157;Reactome: R-HSA-69416;Reactome: R-HSA-933543;Reactome: R-HSA-5357786;Reactome: R-HSA-75158;Reactome: R-HSA-2562578;Reactome: R-HSA-5213460 "Regulation by c-FLIP";"CASP8 activity is inhibited";"TLR3-mediated TICAM1-dependent programmed cell death";"Caspase activation via Death Receptors in the presence of ligand";"FasL/ CD95L signaling";"Dimerization of procaspase-8";"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10";"TNFR1-induced proapoptotic signaling";"TRAIL signaling";"TRIF-mediated programmed cell death";"RIPK1-mediated regulated necrosis" JAMg_model_8621.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" JAMg_model_16209.1 5 Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-9029558 "Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis" JAMg_model_8644.1 10 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-442742;Reactome: R-HSA-444257;KEGG: 05170+2.7.11.1;Reactome: R-HSA-437239 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"RSK activation";"Human immunodeficiency virus 1 infection";"Recycling pathway of L1" JAMg_model_11253.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-174490 "Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"HCMV Late Events";"Membrane binding and targetting of GAG proteins" JAMg_model_3525.1 5 Reactome: R-HSA-532668;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-901042;Reactome: R-HSA-879415 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Calnexin/calreticulin cycle";"Advanced glycosylation endproduct receptor signaling" JAMg_model_10134.2 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" JAMg_model_8647.1 10 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-442742;Reactome: R-HSA-444257;KEGG: 05170+2.7.11.1;Reactome: R-HSA-437239 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"RSK activation";"Human immunodeficiency virus 1 infection";"Recycling pathway of L1" JAMg_model_20391.5 4 KEGG: 00983+6.3.5.2;Reactome: R-HSA-73817;MetaCyc: PWY-7221;KEGG: 00230+6.3.5.2 "Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" JAMg_model_8962.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_7951.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_4265.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_19687.1 4 Reactome: R-HSA-446199;KEGG: 00900+2.5.1.87;Reactome: R-HSA-4755609;MetaCyc: PWY-6129 "Synthesis of Dolichyl-phosphate";"Terpenoid backbone biosynthesis";"Defective DHDDS causes retinitis pigmentosa 59";"Dolichol and dolichyl phosphate biosynthesis" JAMg_model_8153.7 3 Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3 "Serine biosynthesis";"Methane metabolism";"Glycine, serine and threonine metabolism" JAMg_model_16950.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" JAMg_model_19813.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_9277.5 3 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import" JAMg_model_16950.2 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" JAMg_model_551.3 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" JAMg_model_12405.1 3 Reactome: R-HSA-5678771;Reactome: R-HSA-382556;Reactome: R-HSA-1989781 "Defective ABCB4 causes progressive familial intrahepatic cholestasis 3, intrahepatic cholestasis of pregnancy 3 and gallbladder disease 1";"ABC-family proteins mediated transport";"PPARA activates gene expression" JAMg_model_6360.5 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" JAMg_model_6612.3 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" JAMg_model_12972.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_5205.3 7 Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-9639288 "Regulation of PTEN gene transcription";"Macroautophagy";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Amino acids regulate mTORC1" JAMg_model_3198.5 1 Reactome: R-HSA-1483191 "Synthesis of PC" JAMg_model_11411.5 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" JAMg_model_12265.1 13 MetaCyc: PWY-6351;MetaCyc: PWY-8052;Reactome: R-HSA-2871796;Reactome: R-HSA-202433;Reactome: R-HSA-9027277;Reactome: R-HSA-2424491;KEGG: 04070+3.1.4.11;Reactome: R-HSA-2871809;MetaCyc: PWY-7039;Reactome: R-HSA-2029485;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6367 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"FCERI mediated MAPK activation";"Generation of second messenger molecules";"Erythropoietin activates Phospholipase C gamma (PLCG)";"DAP12 signaling";"Phosphatidylinositol signaling system";"FCERI mediated Ca+2 mobilization";"Phosphatidate metabolism, as a signaling molecule";"Role of phospholipids in phagocytosis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism" JAMg_model_9791.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" JAMg_model_9079.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" JAMg_model_10713.2 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" JAMg_model_19133.3 13 KEGG: 00720+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-6728;MetaCyc: PWY-7384;MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5538 "Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate VI" JAMg_model_10854.3 6 Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-176187 "Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress" JAMg_model_20450.1 5 Reactome: R-HSA-499943;MetaCyc: PWY-7185;MetaCyc: PWY-7177;MetaCyc: PWY-7176;KEGG: 00240+6.3.4.2 "Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation I";"UTP and CTP dephosphorylation II";"UTP and CTP de novo biosynthesis";"Pyrimidine metabolism" JAMg_model_13501.3 6 Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689 "L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits" JAMg_model_6869.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" JAMg_model_8459.1 3 Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification" JAMg_model_19365.1 26 Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-9648025;Reactome: R-HSA-389960;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-389977;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"EML4 and NUDC in mitotic spindle formation";"Formation of tubulin folding intermediates by CCT/TriC";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"HCMV Early Events";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Aggrephagy";"Post-chaperonin tubulin folding pathway";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin" JAMg_model_8614.1 14 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-167242 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat" JAMg_model_4945.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" JAMg_model_11724.2 13 Reactome: R-HSA-196836;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-6370;KEGG: 00980+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00053+1.8.5.1;Reactome: R-HSA-156590;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-7533;MetaCyc: PWY-2261;KEGG: 00983+2.5.1.18 "Vitamin C (ascorbate) metabolism";"Glutathione metabolism";"Ascorbate recycling (cytosolic)";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Ascorbate and aldarate metabolism";"Glutathione conjugation";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Ascorbate glutathione cycle";"Drug metabolism - other enzymes" JAMg_model_299.2 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" JAMg_model_12279.1 18 KEGG: 00250+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00270+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-6643;MetaCyc: PWY-6638;MetaCyc: PWY-7115;KEGG: 00360+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00400+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00350+2.6.1.1;KEGG: 00950+2.6.1.1 "Alanine, aspartate and glutamate metabolism";"Novobiocin biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Cysteine and methionine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Coenzyme M biosynthesis II";"Sulfolactate degradation III";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Phenylalanine metabolism";"Arginine biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Arginine and proline metabolism";"Carbon fixation in photosynthetic organisms";"(R)-cysteate degradation";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis" JAMg_model_20869.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" JAMg_model_12468.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" JAMg_model_4972.2 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" JAMg_model_13043.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_799.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_21160.2 4 KEGG: 00750+1.4.3.5;MetaCyc: PWY-7204;Reactome: R-HSA-964975;MetaCyc: PWY-7282 "Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis" JAMg_model_13226.1 3 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109 "Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis" JAMg_model_18910.2 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" JAMg_model_4828.3 3 Reactome: R-HSA-525793;Reactome: R-HSA-9634638;Reactome: R-HSA-5663220 "Myogenesis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins" JAMg_model_7189.3 12 KEGG: 05163+2.7.11.1;Reactome: R-HSA-418885;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-416476;KEGG: 05165+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"DCC mediated attractive signaling";"Human immunodeficiency virus 1 infection";"G alpha (12/13) signalling events";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"NRAGE signals death through JNK";"G alpha (q) signalling events";"Human papillomavirus infection";"Rho GTPase cycle";"Thermogenesis" JAMg_model_1524.1 5 Reactome: R-HSA-5083630;Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-1912399;Reactome: R-HSA-1912420 "Defective LFNG causes SCDO3";"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Pre-NOTCH Processing in Golgi" JAMg_model_15526.1 7 MetaCyc: PWY-7210;MetaCyc: PWY-7185;MetaCyc: PWY-6545;KEGG: 00730+3.6.1.15;MetaCyc: PWY-7184;KEGG: 00230+3.6.1.15;MetaCyc: PWY-7198 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" JAMg_model_990.4 14 KEGG: 00260+2.1.2.1;MetaCyc: PWY-1622;MetaCyc: PWY-5497;MetaCyc: PWY-2201;KEGG: 00670+2.1.2.1;MetaCyc: PWY-3661-1;MetaCyc: PWY-181;MetaCyc: PWY-3661;MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00680+2.1.2.1;KEGG: 00630+2.1.2.1;MetaCyc: PWY-3841;KEGG: 00460+2.1.2.1 "Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"One carbon pool by folate";"Glycine betaine degradation II (mammalian)";"Photorespiration ";"Glycine betaine degradation I";"Folate polyglutamylation";"Metabolism of folate and pterines";"Methane metabolism";"Glyoxylate and dicarboxylate metabolism";"Folate transformations II (plants)";"Cyanoamino acid metabolism" JAMg_model_10060.2 2 KEGG: 00260+2.3.1.29;Reactome: R-HSA-8849175 "Glycine, serine and threonine metabolism";"Threonine catabolism" JAMg_model_16966.4 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" JAMg_model_20389.3 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" JAMg_model_1523.5 2 Reactome: R-HSA-8949613;Reactome: R-HSA-1268020 "Cristae formation";"Mitochondrial protein import" JAMg_model_9932.4 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_16586.2 3 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10;Reactome: R-HSA-6783984 "Glycine, serine and threonine metabolism";"One carbon pool by folate";"Glycine degradation" JAMg_model_13458.1 2 Reactome: R-HSA-5673001;Reactome: R-HSA-442982 "RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor" JAMg_model_13201.2 9 Reactome: R-HSA-1971475;Reactome: R-HSA-975634;Reactome: R-HSA-3560783;Reactome: R-HSA-2022928;Reactome: R-HSA-2024096;Reactome: R-HSA-4420332;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237 "A tetrasaccharide linker sequence is required for GAG synthesis";"Retinoid metabolism and transport";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis";"HS-GAG degradation";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2" JAMg_model_8807.3 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway" JAMg_model_15438.2 17 Reactome: R-HSA-937042;Reactome: R-HSA-445989;Reactome: R-HSA-4086398;Reactome: R-HSA-5607764;Reactome: R-HSA-168638;Reactome: R-HSA-937072;Reactome: R-HSA-450321;Reactome: R-HSA-5689880;Reactome: R-HSA-975163;Reactome: R-HSA-9645460;Reactome: R-HSA-202424;Reactome: R-HSA-9020702;Reactome: R-HSA-5357956;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-450302;Reactome: R-HSA-9014325 "IRAK2 mediated activation of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Ca2+ pathway";"CLEC7A (Dectin-1) signaling";"NOD1/2 Signaling Pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Ub-specific processing proteases";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Alpha-protein kinase 1 signaling pathway";"Downstream TCR signaling";"Interleukin-1 signaling";"TNFR1-induced NFkappaB signaling pathway";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"activated TAK1 mediates p38 MAPK activation";"TICAM1,TRAF6-dependent induction of TAK1 complex" JAMg_model_5304.1 5 MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis" JAMg_model_14921.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" JAMg_model_14049.1 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" JAMg_model_18337.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_15651.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" JAMg_model_5119.3 11 Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-69017;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68827 "E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"CDK-mediated phosphorylation and removal of Cdc6";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex" JAMg_model_16435.2 13 Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Viral mRNA Translation" JAMg_model_19971.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" JAMg_model_16752.2 2 Reactome: R-HSA-3108214;Reactome: R-HSA-5685938 "SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)" JAMg_model_4741.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" JAMg_model_9166.1 3 Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.19 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis" JAMg_model_10093.5 1 Reactome: R-HSA-5620924 "Intraflagellar transport" JAMg_model_1142.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369 "Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis" JAMg_model_2047.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" JAMg_model_9054.8 3 MetaCyc: PWY-6117;KEGG: 00330+2.3.1.57;MetaCyc: PWY-0 "Spermine and spermidine degradation I";"Arginine and proline metabolism";"Putrescine degradation III" JAMg_model_14966.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" JAMg_model_18047.2 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" JAMg_model_11532.2 20 Reactome: R-HSA-1257604;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-166208;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5628897;KEGG: 05163+2.7.11.1;Reactome: R-HSA-389357;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-380972 "PIP3 activates AKT signaling";"Amino acids regulate mTORC1";"Macroautophagy";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTORC1-mediated signalling";"Relaxin signaling pathway";"TP53 Regulates Metabolic Genes";"Human cytomegalovirus infection";"CD28 dependent PI3K/Akt signaling";"Human immunodeficiency virus 1 infection";"VEGFR2 mediated vascular permeability";"HSF1-dependent transactivation";"mTOR signalling";"Regulation of PTEN gene transcription";"Thermogenesis";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"Energy dependent regulation of mTOR by LKB1-AMPK" JAMg_model_10872.1 9 MetaCyc: PWY-7003;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-6901;MetaCyc: PWY-5484;Reactome: R-HSA-70263;KEGG: 00010+1.2.1.12;KEGG: 00710+1.2.1.12;MetaCyc: PWY-8004 "Glycerol degradation to butanol";"Glycolysis";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Entner-Doudoroff pathway I" JAMg_model_9900.2 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" JAMg_model_7336.1 4 KEGG: 00513+2.4.1.260;Reactome: R-HSA-4720489;KEGG: 00510+2.4.1.260;Reactome: R-HSA-446193 "Various types of N-glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" JAMg_model_18900.1 20 Reactome: R-HSA-6782210;Reactome: R-HSA-176187;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5696397;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-6804756;Reactome: R-HSA-174411;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-5685938 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of ATR in response to replication stress";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Polymerase switching";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of TP53 Activity through Phosphorylation";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Single Strand Annealing (SSA)" JAMg_model_9706.2 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" JAMg_model_8370.2 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" JAMg_model_17048.1 8 KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"mTOR signaling pathway";"T cell receptor signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" JAMg_model_628.1 6 KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-2221;MetaCyc: PWY-5530;KEGG: 00053+3.1.1.17;KEGG: 00930+3.1.1.17 "Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II";"Ascorbate and aldarate metabolism";"Caprolactam degradation" JAMg_model_1523.11 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8949613 "Mitochondrial protein import";"Cristae formation" JAMg_model_20334.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" JAMg_model_13381.4 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" JAMg_model_10334.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" JAMg_model_18142.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" JAMg_model_1359.4 12 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-416476;KEGG: 04926+2.7.11.1;Reactome: R-HSA-418885;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Rho GTPase cycle";"Human papillomavirus infection";"Thermogenesis";"NRAGE signals death through JNK";"G alpha (q) signalling events";"Relaxin signaling pathway";"DCC mediated attractive signaling";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"Human immunodeficiency virus 1 infection" JAMg_model_20380.1 10 Reactome: R-HSA-1483191;Reactome: R-HSA-8939243;Reactome: R-HSA-2514853;Reactome: R-HSA-8948751;Reactome: R-HSA-445144;Reactome: R-HSA-8934903;Reactome: R-HSA-6814122;Reactome: R-HSA-6804756;Reactome: R-HSA-201688;Reactome: R-HSA-6798695 "Synthesis of PC";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Condensation of Prometaphase Chromosomes";"Regulation of PTEN stability and activity";"Signal transduction by L1";"Receptor Mediated Mitophagy";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of TP53 Activity through Phosphorylation";"WNT mediated activation of DVL";"Neutrophil degranulation" JAMg_model_2429.1 24 Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295 "Kinesins";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"HCMV Early Events";"Mitotic Prometaphase";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Cilium Assembly";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation" JAMg_model_12415.1 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" JAMg_model_13068.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_13968.2 1 Reactome: R-HSA-5620924 "Intraflagellar transport" JAMg_model_15031.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" JAMg_model_2629.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" JAMg_model_8852.3 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" JAMg_model_1515.1 1 Reactome: R-HSA-1483101 "Synthesis of PS" JAMg_model_4620.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" JAMg_model_238.2 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" JAMg_model_3870.1 2 Reactome: R-HSA-3065678;Reactome: R-HSA-3065676 "SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"SUMO is conjugated to E1 (UBA2:SAE1)" JAMg_model_1010.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" JAMg_model_6333.4 10 MetaCyc: PWY-5892;MetaCyc: PWY-5844;MetaCyc: PWY-5895;MetaCyc: PWY-7996;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5891;Reactome: R-HSA-2142789;MetaCyc: PWY-5890;MetaCyc: PWY-5849;MetaCyc: PWY-5839 "Menaquinol-12 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-4 biosynthesis I";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-11 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-7 biosynthesis" JAMg_model_19942.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" JAMg_model_18090.3 4 Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22;KEGG: 00790+4.6.1.17;MetaCyc: PWY-6823 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" JAMg_model_10124.2 6 KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;Reactome: R-HSA-71403;KEGG: 00630+4.2.1.3;Reactome: R-HSA-1268020;KEGG: 00720+4.2.1.3 "Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Citric acid cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Mitochondrial protein import";"Carbon fixation pathways in prokaryotes" JAMg_model_3076.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" JAMg_model_12770.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" JAMg_model_1274.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" JAMg_model_18298.1 3 KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1 "Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis" JAMg_model_5107.3 6 Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase" JAMg_model_13907.2 5 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-204005;Reactome: R-HSA-6811438;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport";"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_14956.2 2 Reactome: R-HSA-380320;Reactome: R-HSA-68875 "Recruitment of NuMA to mitotic centrosomes";"Mitotic Prophase" JAMg_model_359.6 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" JAMg_model_5088.2 16 Reactome: R-HSA-70171;MetaCyc: PWY-7003;KEGG: 00680+4.2.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-8004;MetaCyc: PWY-1622;MetaCyc: PWY-6886;Reactome: R-HSA-70263;MetaCyc: PWY-5723;MetaCyc: PWY-6142;KEGG: 00010+4.2.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-6901;MetaCyc: PWY-7218;MetaCyc: PWY-7124;MetaCyc: PWY-2221 "Glycolysis";"Glycerol degradation to butanol";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis";"Rubisco shunt";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Ethylene biosynthesis V (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)" JAMg_model_12288.1 7 KEGG: 00600+2.4.1.80;MetaCyc: PWY-7838;MetaCyc: PWY-7841;MetaCyc: PWY-5129;MetaCyc: PWY-7836;Reactome: R-HSA-1660662;MetaCyc: PWY-7839 "Sphingolipid metabolism";"Globo-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Ganglio-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Lacto-series glycosphingolipids biosynthesis" JAMg_model_20172.3 9 Reactome: R-HSA-416476;MetaCyc: PWY-6351;MetaCyc: PWY-8052;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;KEGG: 04070+3.1.4.11 "G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"Phosphatidylinositol signaling system" JAMg_model_2168.1 12 KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803 "Linoleic acid metabolism";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing" JAMg_model_1400.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" JAMg_model_18884.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" JAMg_model_9564.3 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_13323.3 3 Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-110357 "Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1" JAMg_model_14920.2 8 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Signaling by Hippo";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway" JAMg_model_6300.1 6 MetaCyc: PWY-3341;MetaCyc: PWY-6344;MetaCyc: PWY-4981;MetaCyc: PWY-6922;KEGG: 00330+2.6.1.13;Reactome: R-HSA-8964539 "L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Glutamate and glutamine metabolism" JAMg_model_6360.3 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" JAMg_model_12705.2 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" JAMg_model_5776.3 3 Reactome: R-HSA-2408508;Reactome: R-HSA-1614558;Reactome: R-HSA-1614603 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine" JAMg_model_11842.4 17 Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Viral mRNA Translation" JAMg_model_17283.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_2130.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_6863.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_8478.3 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" JAMg_model_20590.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" JAMg_model_7875.1 1 Reactome: R-HSA-8849175 "Threonine catabolism" JAMg_model_14312.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" JAMg_model_15704.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" JAMg_model_17252.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" JAMg_model_11787.1 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" JAMg_model_7500.1 19 KEGG: 00640+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7606;MetaCyc: PWY-7007;MetaCyc: PWY-5136;MetaCyc: PWY-7340;MetaCyc: PWY-6920;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7574;MetaCyc: PWY-7338;MetaCyc: PWY-7288;MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-735;MetaCyc: PWY-7291 "Propanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoyl-coa degradation II";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)" JAMg_model_3435.2 6 Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-429958 "Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease" JAMg_model_1909.2 1 Reactome: R-HSA-8949664 "Processing of SMDT1" JAMg_model_19452.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" JAMg_model_15557.1 5 KEGG: 00330+1.14.13.39;Reactome: R-HSA-1222556;MetaCyc: PWY-4983;Reactome: R-HSA-392154;KEGG: 00220+1.14.13.39 "Arginine and proline metabolism";"ROS and RNS production in phagocytes";"Nitric oxide biosynthesis II (mammals)";"Nitric oxide stimulates guanylate cyclase";"Arginine biosynthesis" JAMg_model_12129.3 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" JAMg_model_19590.1 5 Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-201722;Reactome: R-HSA-112382 "E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the beta-catenin:TCF transactivating complex";"Formation of RNA Pol II elongation complex" JAMg_model_10267.2 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" JAMg_model_20331.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" JAMg_model_4603.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" JAMg_model_15875.1 1 Reactome: R-HSA-8949613 "Cristae formation" JAMg_model_3410.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72695 "Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex" JAMg_model_2886.2 10 Reactome: R-HSA-9027276;KEGG: 00562+2.7.1.153;KEGG: 04150+2.7.1.153;KEGG: 04070+2.7.1.153;KEGG: 04151+2.7.1.153;KEGG: 05170+2.7.1.153;Reactome: R-HSA-1660499;MetaCyc: PWY-6352;KEGG: 05165+2.7.1.153;KEGG: 05163+2.7.1.153 "Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Inositol phosphate metabolism";"mTOR signaling pathway";"Phosphatidylinositol signaling system";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide biosynthesis";"Human papillomavirus infection";"Human cytomegalovirus infection" JAMg_model_9121.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6798695 "COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation" JAMg_model_21315.8 15 KEGG: 00230+2.7.1.40;KEGG: 00010+2.7.1.40;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-1042;MetaCyc: PWY-7383;MetaCyc: PWY-7218;MetaCyc: PWY-6886;MetaCyc: PWY-8004;MetaCyc: PWY-2221;MetaCyc: PWY-5723;Reactome: R-HSA-70171;MetaCyc: PWY-7003;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6142 "Purine metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Rubisco shunt";"Glycolysis";"Glycerol degradation to butanol";"Pyruvate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" JAMg_model_5561.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288 "Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1" JAMg_model_4005.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" JAMg_model_17489.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" JAMg_model_3886.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" JAMg_model_2678.3 3 KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I" JAMg_model_16896.1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" JAMg_model_8481.4 2 Reactome: R-HSA-203927;Reactome: R-HSA-8986944 "MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2" JAMg_model_17943.1 5 Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-111447 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria" JAMg_model_997.4 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" JAMg_model_13394.3 7 MetaCyc: PWY-3385;MetaCyc: PWY-7782;Reactome: R-HSA-1483191;Reactome: R-HSA-1483213;MetaCyc: PWY-7818;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7886 "Choline biosynthesis I";"Plasmalogen biosynthesis";"Synthesis of PC";"Synthesis of PE";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Glycerophospholipid metabolism";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis" JAMg_model_1216.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_12313.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" JAMg_model_15802.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-8876725 "Respiratory electron transport";"Protein methylation" JAMg_model_12779.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-429958 "Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease" JAMg_model_6228.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" JAMg_model_20523.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway" JAMg_model_10689.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450385 "KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" JAMg_model_21015.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" JAMg_model_4222.1 7 Reactome: R-HSA-171306;Reactome: R-HSA-110329;Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-110328;Reactome: R-HSA-2559586;Reactome: R-HSA-1221632 "Packaging Of Telomere Ends";"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Meiotic synapsis" JAMg_model_13997.3 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" JAMg_model_10213.1 8 Reactome: R-HSA-163754;Reactome: R-HSA-6791462;MetaCyc: PWY-1861;Reactome: R-HSA-6791055;Reactome: R-HSA-71336;KEGG: 00030+2.2.1.2;MetaCyc: PWY-5723;Reactome: R-HSA-8950505 "Insulin effects increased synthesis of Xylulose-5-Phosphate";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Pentose phosphate pathway";"Pentose phosphate pathway";"Rubisco shunt";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" JAMg_model_4787.1 6 Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163 "Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway" JAMg_model_11685.2 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" JAMg_model_14563.2 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" JAMg_model_11739.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_2904.3 3 Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294 "SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors" JAMg_model_13054.11 3 MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism" JAMg_model_6042.5 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" JAMg_model_6469.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" JAMg_model_1190.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" JAMg_model_3319.4 22 MetaCyc: PWY-7117;KEGG: 00960+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-6638;KEGG: 00350+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-6642;Reactome: R-HSA-72163;KEGG: 00400+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00270+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00250+2.6.1.1;Reactome: R-HSA-159236;MetaCyc: PWY-6643;Reactome: R-HSA-72187;MetaCyc: PWY-7383;Reactome: R-HSA-73856 "C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine metabolism";"Arginine biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Sulfolactate degradation III";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"(R)-cysteate degradation";"mRNA Splicing - Major Pathway";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Carbon fixation in photosynthetic organisms";"Arginine and proline metabolism";"Partial TCA cycle (obligate autotrophs)";"Cysteine and methionine metabolism";"Novobiocin biosynthesis";"Alanine, aspartate and glutamate metabolism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Coenzyme M biosynthesis II";"mRNA 3'-end processing";"Anaerobic energy metabolism (invertebrates, cytosol)";"RNA Polymerase II Transcription Termination" JAMg_model_14505.2 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" JAMg_model_1489.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" JAMg_model_1909.4 1 Reactome: R-HSA-8949664 "Processing of SMDT1" JAMg_model_3430.6 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" JAMg_model_21258.2 8 KEGG: 00190+7.1.2.2;Reactome: R-HSA-983712;MetaCyc: PWY-7980;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387;KEGG: 00195+7.1.2.2;Reactome: R-HSA-9639288 "Oxidative phosphorylation";"Ion channel transport";"ATP biosynthesis";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Photosynthesis";"Amino acids regulate mTORC1" JAMg_model_18817.1 10 KEGG: 00030+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-7385 "Pentose phosphate pathway";"Glycolysis";"Fructose and mannose metabolism";"Methane metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"1,3-propanediol biosynthesis (engineered)" JAMg_model_7638.5 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_4999.2 11 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167287 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery" JAMg_model_15187.1 5 Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-5625740 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs" JAMg_model_5079.1 13 MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2024101 "Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"CS/DS degradation" JAMg_model_9194.6 6 MetaCyc: PWY-7234;KEGG: 00230+3.5.4.10+2.1.2.3;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.3;MetaCyc: PWY-6124;MetaCyc: PWY-6123 "Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I" JAMg_model_4443.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" JAMg_model_12527.1 3 MetaCyc: PWY-4361;KEGG: 00270+1.13.11.54;Reactome: R-HSA-1237112 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Methionine salvage pathway" JAMg_model_4972.3 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" JAMg_model_14616.1 1 Reactome: R-HSA-1483255 "PI Metabolism" JAMg_model_4480.1 6 Reactome: R-HSA-9609690;Reactome: R-HSA-9029569;Reactome: R-HSA-1989781;Reactome: R-HSA-9022692;Reactome: R-HSA-3214815;Reactome: R-HSA-9022537 "HCMV Early Events";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"PPARA activates gene expression";"Regulation of MECP2 expression and activity";"HDACs deacetylate histones";"Loss of MECP2 binding ability to the NCoR/SMRT complex" JAMg_model_16618.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" JAMg_model_2904.2 3 Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294 "SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors" JAMg_model_5924.2 3 MetaCyc: PWY-7511;Reactome: R-HSA-349425;Reactome: R-HSA-8951664 "Protein ubiquitination";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation" JAMg_model_9895.6 10 MetaCyc: PWY-6527;KEGG: 00052+5.1.3.2;MetaCyc: PWY-3821;MetaCyc: PWY-6317;MetaCyc: PWY-7344;MetaCyc: PWY-7328;KEGG: 00520+5.1.3.2;Reactome: R-HSA-5609977;MetaCyc: PWY-6397;Reactome: R-HSA-70370 "Stachyose degradation";"Galactose metabolism";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"UDP-alpha-D-galactose biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose catabolism" JAMg_model_21203.1 2 Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2 "Glycine degradation";"Glycine, serine and threonine metabolism" JAMg_model_10797.1 1 Reactome: R-HSA-5676934 "Protein repair" JAMg_model_19672.2 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" JAMg_model_546.1 4 Reactome: R-HSA-2408522;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" JAMg_model_18050.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_21130.3 6 Reactome: R-HSA-9033241;Reactome: R-HSA-9615017;KEGG: 00630+1.11.1.6;Reactome: R-HSA-6798695;KEGG: 00380+1.11.1.6;Reactome: R-HSA-3299685 "Peroxisomal protein import";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Glyoxylate and dicarboxylate metabolism";"Neutrophil degranulation";"Tryptophan metabolism";"Detoxification of Reactive Oxygen Species" JAMg_model_11401.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_17419.5 12 Reactome: R-HSA-380270;Reactome: R-HSA-381038;Reactome: R-HSA-380284;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-6807878;Reactome: R-HSA-8854518 "Recruitment of mitotic centrosome proteins and complexes";"XBP1(S) activates chaperone genes";"Loss of proteins required for interphase microtubule organization from the centrosome";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"COPI-mediated anterograde transport";"AURKA Activation by TPX2" JAMg_model_16972.1 9 Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-110329;Reactome: R-HSA-9657050;Reactome: R-HSA-9656256;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-5649702;Reactome: R-HSA-9656255 "Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Cleavage of the damaged pyrimidine";"Defective OGG1 Localization";"Defective OGG1 Substrate Processing";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Defective OGG1 Substrate Binding" JAMg_model_9184.4 6 MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism" JAMg_model_1965.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" JAMg_model_13588.3 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_583.10 1 Reactome: R-HSA-71384 "Ethanol oxidation" JAMg_model_3614.1 4 KEGG: 00520+2.7.1.59;Reactome: R-HSA-446210;MetaCyc: PWY-6517;MetaCyc: PWY-6906 "Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II";"Chitin derivatives degradation" JAMg_model_20497.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" JAMg_model_11694.3 11 Reactome: R-HSA-8940973;Reactome: R-HSA-8939236;Reactome: R-HSA-69231;Reactome: R-HSA-5693565;KEGG: 04660+2.7.10.2;Reactome: R-HSA-983231;Reactome: R-HSA-525793;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-428890;Reactome: R-HSA-5685938 "RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin D associated events in G1";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"T cell receptor signaling pathway";"Factors involved in megakaryocyte development and platelet production";"Myogenesis";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Role of ABL in ROBO-SLIT signaling";"HDR through Single Strand Annealing (SSA)" JAMg_model_14841.1 31 MetaCyc: PWY-5989;MetaCyc: PWY-5147;Reactome: R-HSA-9029558;MetaCyc: PWY-5966-1;MetaCyc: PWY-7664;MetaCyc: PWY-5973;Reactome: R-HSA-75105;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6113;MetaCyc: PWY-6282;MetaCyc: PWY-4381;Reactome: R-HSA-2426168;MetaCyc: PWY-6519;MetaCyc: PWY-8012;MetaCyc: PWY-6799;MetaCyc: PWYG-321;MetaCyc: PWY-5367;MetaCyc: PWY-7746;MetaCyc: PWY-5994;Reactome: R-HSA-199220;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7388;MetaCyc: PWY-5366;MetaCyc: PWY-7663;MetaCyc: PWY-7723;MetaCyc: PWY-5971;MetaCyc: PWY-8049;MetaCyc: PWY-8047;MetaCyc: PWY-7858;Reactome: R-HSA-163765;MetaCyc: PWY-5142 "Stearate biosynthesis II (bacteria and plants)";"Oleate biosynthesis I (plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Oleate biosynthesis IV (anaerobic)";"Cis-vaccenate biosynthesis";"Fatty acyl-CoA biosynthesis";"Biotin metabolism";"Superpathway of mycolate biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"8-amino-7-oxononanoate biosynthesis I";"Mupirocin biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"";"Petroselinate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"Fatty acid biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitoleate biosynthesis II (plants and bacteria)";"Gondoate biosynthesis (anaerobic)";"Bacterial bioluminescence";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Pederin biosynthesis";"Bryostatin biosynthesis";"(5Z)-dodecenoate biosynthesis II";"ChREBP activates metabolic gene expression";"Acyl-[acyl-carrier protein] thioesterase pathway" JAMg_model_18117.5 12 MetaCyc: PWY-1187;MetaCyc: PWY-6936;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6309;KEGG: 00380+2.6.1.7;MetaCyc: PWY-601;MetaCyc: PWY-6842;MetaCyc: PWY-7901;Reactome: R-HSA-71240;MetaCyc: PWY-801;MetaCyc: PWY-2821;KEGG: 00270+4.4.1.13 "Glucosinolate biosynthesis from homomethionine";"Seleno-amino acid biosynthesis (plants)";"Selenocompound metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"Glucosinolate biosynthesis from tryptophan";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from tyrosine";"Tryptophan catabolism";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from phenylalanine";"Cysteine and methionine metabolism" JAMg_model_859.2 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" JAMg_model_6355.2 4 Reactome: R-HSA-400511;Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-1799339 "Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane" JAMg_model_10342.2 2 Reactome: R-HSA-164843;Reactome: R-HSA-5693571 "2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)" JAMg_model_10328.4 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" JAMg_model_8298.1 4 Reactome: R-HSA-1912420;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" JAMg_model_6955.1 1 Reactome: R-HSA-912446 "Meiotic recombination" JAMg_model_5921.1 6 Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-6814122 "Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" JAMg_model_17486.2 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1362409 "Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis" JAMg_model_7189.8 12 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-193648;KEGG: 04926+2.7.11.1;Reactome: R-HSA-418885;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Rho GTPase cycle";"Thermogenesis";"Human papillomavirus infection";"G alpha (q) signalling events";"NRAGE signals death through JNK";"Relaxin signaling pathway";"DCC mediated attractive signaling";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"Human immunodeficiency virus 1 infection" JAMg_model_10124.3 6 KEGG: 00020+4.2.1.3;Reactome: R-HSA-71403;KEGG: 00290+4.2.1.33;Reactome: R-HSA-1268020;KEGG: 00720+4.2.1.3;KEGG: 00630+4.2.1.3 "Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Mitochondrial protein import";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism" JAMg_model_14307.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis" JAMg_model_21089.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" JAMg_model_4436.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" JAMg_model_3322.1 56 Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-69601;Reactome: R-HSA-5362768 "SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"FCERI mediated NF-kB activation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" JAMg_model_16066.4 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_19053.1 7 KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-6824 "Phenylpropanoid biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis" JAMg_model_19265.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" JAMg_model_17419.8 12 Reactome: R-HSA-381038;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-6807878 "XBP1(S) activates chaperone genes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"COPI-mediated anterograde transport" JAMg_model_9874.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_15223.1 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_7209.2 56 Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813 "Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids" JAMg_model_3086.3 14 Reactome: R-HSA-205043;Reactome: R-HSA-977225;Reactome: R-HSA-1251985;Reactome: R-HSA-9017802;Reactome: R-HSA-193692;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-3928665;Reactome: R-HSA-9013700;Reactome: R-HSA-2122948;Reactome: R-HSA-6798695;Reactome: R-HSA-2644606;Reactome: R-HSA-1474228 "NRIF signals cell death from the nucleus";"Amyloid fiber formation";"Nuclear signaling by ERBB4";"Noncanonical activation of NOTCH3";"Regulated proteolysis of p75NTR";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Neutrophil degranulation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Degradation of the extracellular matrix" JAMg_model_11877.1 6 Reactome: R-HSA-189085;MetaCyc: PWY-622;MetaCyc: PWY-5067;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1;KEGG: 00500+2.4.1.18 "Digestion of dietary carbohydrate";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch and sucrose metabolism" JAMg_model_11748.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" JAMg_model_1124.2 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" JAMg_model_8008.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_10427.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_4128.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" JAMg_model_12183.1 3 Reactome: R-HSA-5358493;MetaCyc: PWY-7546;MetaCyc: PWY-6482 "Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)" JAMg_model_18210.5 5 MetaCyc: PWY-7560;MetaCyc: PWY-6891;MetaCyc: PWY-6892;KEGG: 00730+2.2.1.7;KEGG: 00900+2.2.1.7 "Methylerythritol phosphate pathway II";"Thiazole biosynthesis II (aerobic bacteria)";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiamine metabolism";"Terpenoid backbone biosynthesis" JAMg_model_4874.4 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" JAMg_model_1732.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits" JAMg_model_12887.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" JAMg_model_2748.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" JAMg_model_6136.1 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_10955.1 1 Reactome: R-HSA-6798163 "Choline catabolism" JAMg_model_18125.3 9 MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52 "Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation" JAMg_model_17201.2 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" JAMg_model_9895.3 10 Reactome: R-HSA-70370;MetaCyc: PWY-6397;Reactome: R-HSA-5609977;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7328;MetaCyc: PWY-7344;MetaCyc: PWY-6317;MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00052+5.1.3.2 "Galactose catabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Amino sugar and nucleotide sugar metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"UDP-alpha-D-galactose biosynthesis";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Stachyose degradation";"Galactose metabolism" JAMg_model_12337.3 26 Reactome: R-HSA-1912408;Reactome: R-HSA-3899300;Reactome: R-HSA-8941856;Reactome: R-HSA-1234158;Reactome: R-HSA-201722;Reactome: R-HSA-933541;Reactome: R-HSA-210744;Reactome: R-HSA-9018519;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-9614657;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-8866907;Reactome: R-HSA-400253;Reactome: R-HSA-3214847;Reactome: R-HSA-381340;Reactome: R-HSA-9617629;Reactome: R-HSA-3134973;Reactome: R-HSA-5621575;Reactome: R-HSA-1989781;Reactome: R-HSA-9013508;Reactome: R-HSA-9013695;Reactome: R-HSA-1368082;Reactome: R-HSA-2122947 "Pre-NOTCH Transcription and Translation";"SUMOylation of transcription cofactors";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"Formation of the beta-catenin:TCF transactivating complex";"TRAF6 mediated IRF7 activation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Estrogen-dependent gene expression";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"FOXO-mediated transcription of cell death genes";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activation of the TFAP2 (AP-2) family of transcription factors";"Circadian Clock";"HATs acetylate histones";"Transcriptional regulation of white adipocyte differentiation";"Regulation of FOXO transcriptional activity by acetylation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"CD209 (DC-SIGN) signaling";"PPARA activates gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription" JAMg_model_16462.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" JAMg_model_8910.5 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" JAMg_model_5320.1 1 Reactome: R-HSA-211981 "Xenobiotics" JAMg_model_19268.1 2 KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921 "Histidine metabolism";"Histidine catabolism" JAMg_model_16195.2 56 Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-350562;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-4641257;Reactome: R-HSA-174084 "Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Regulation of ornithine decarboxylase (ODC)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C" JAMg_model_5555.2 7 MetaCyc: PWY-6351;Reactome: R-HSA-1660499;Reactome: R-HSA-1660514;KEGG: 04070+2.7.1.67;MetaCyc: PWY-6352;KEGG: 00562+2.7.1.67;Reactome: R-HSA-1660516 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the Golgi membrane";"Phosphatidylinositol signaling system";"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane" JAMg_model_14808.1 1 Reactome: R-HSA-525793 "Myogenesis" JAMg_model_20813.2 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" JAMg_model_6732.1 56 Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-174184 "GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"UCH proteinases";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A" JAMg_model_9249.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" JAMg_model_11500.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" JAMg_model_1719.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288 "Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1" JAMg_model_1274.3 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" JAMg_model_17775.2 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" JAMg_model_18905.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_5588.9 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" JAMg_model_12196.1 1 Reactome: R-HSA-74217 "Purine salvage" JAMg_model_19221.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" JAMg_model_14518.5 1 Reactome: R-HSA-5620924 "Intraflagellar transport" JAMg_model_10663.3 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" JAMg_model_6185.1 15 Reactome: R-HSA-6804756;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5685939;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693548 "Regulation of TP53 Activity through Phosphorylation";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through MMEJ (alt-NHEJ)";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Sensing of DNA Double Strand Breaks" JAMg_model_2447.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" JAMg_model_8116.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" JAMg_model_2682.3 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" JAMg_model_15441.6 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" JAMg_model_4161.1 3 KEGG: 00511+3.2.1.45;KEGG: 00600+3.2.1.45;Reactome: R-HSA-1660662 "Other glycan degradation";"Sphingolipid metabolism";"Glycosphingolipid metabolism" JAMg_model_627.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" JAMg_model_19081.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" JAMg_model_6525.3 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" JAMg_model_14928.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" JAMg_model_1643.3 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" JAMg_model_8439.1 5 Reactome: R-HSA-5696397;Reactome: R-HSA-110381;Reactome: R-HSA-6782210;Reactome: R-HSA-5685939;Reactome: R-HSA-5649702 "Gap-filling DNA repair synthesis and ligation in GG-NER";"Resolution of AP sites via the single-nucleotide replacement pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through MMEJ (alt-NHEJ)";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" JAMg_model_10134.6 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" JAMg_model_7416.2 1 Reactome: R-HSA-2468052 "Establishment of Sister Chromatid Cohesion" JAMg_model_3961.2 3 KEGG: 00310+1.14.11.8;MetaCyc: PWY-6100;Reactome: R-HSA-71262 "Lysine degradation";"L-carnitine biosynthesis";"Carnitine synthesis" JAMg_model_15441.7 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" JAMg_model_19735.1 14 KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;Reactome: R-HSA-975634;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4+3.1.1.5 "Linoleic acid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Retinoid metabolism and transport";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism" JAMg_model_8264.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_5112.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_4222.2 7 Reactome: R-HSA-110329;Reactome: R-HSA-110331;Reactome: R-HSA-171306;Reactome: R-HSA-110330;Reactome: R-HSA-1221632;Reactome: R-HSA-110328;Reactome: R-HSA-2559586 "Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine";"Packaging Of Telomere Ends";"Recognition and association of DNA glycosylase with site containing an affected purine";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"DNA Damage/Telomere Stress Induced Senescence" JAMg_model_10005.2 4 MetaCyc: PWY-7383;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8040;MetaCyc: PWY-8072 "Anaerobic energy metabolism (invertebrates, cytosol)";"D-Alanine metabolism";"Ansatrienin biosynthesis";"Alanine racemization" JAMg_model_8700.1 8 Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-6798695 "TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"mTOR signalling";"Regulation of PTEN gene transcription";"Macroautophagy";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Neutrophil degranulation" JAMg_model_1571.4 3 Reactome: R-HSA-390471;Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Association of TriC/CCT with target proteins during biosynthesis";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_1264.2 3 Reactome: R-HSA-1660517;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514 "Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane" JAMg_model_6193.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" JAMg_model_7381.1 7 MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-5466 "Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Matairesinol biosynthesis" JAMg_model_5771.1 14 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-5620912;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-68877;Reactome: R-HSA-428890;Reactome: R-HSA-380284;Reactome: R-HSA-5663220;Reactome: R-HSA-2565942;Reactome: R-HSA-141444 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Anchoring of the basal body to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Mitotic Prometaphase";"Role of ABL in ROBO-SLIT signaling";"Loss of proteins required for interphase microtubule organization from the centrosome";"RHO GTPases Activate Formins";"Regulation of PLK1 Activity at G2/M Transition";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" JAMg_model_11740.4 9 Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-6784531;Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-69091 "Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"tRNA processing in the nucleus";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Removal of the Flap Intermediate";"Polymerase switching" JAMg_model_20124.1 1 Reactome: R-HSA-8876725 "Protein methylation" JAMg_model_13581.1 2 Reactome: R-HSA-532668;Reactome: R-HSA-6798695 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation" JAMg_model_2514.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" JAMg_model_7156.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825 "Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis" JAMg_model_9766.1 7 KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6351;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-1855204 "Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol" JAMg_model_6520.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" JAMg_model_5921.3 6 Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-6814122 "Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" JAMg_model_19912.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" JAMg_model_5668.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" JAMg_model_18372.1 3 Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894 "Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation" JAMg_model_19962.3 16 Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72689 "Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Viral mRNA Translation";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits" JAMg_model_13468.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827 "Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression" JAMg_model_7252.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" JAMg_model_18891.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" JAMg_model_10902.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" JAMg_model_19822.1 19 MetaCyc: PWY-6728;KEGG: 00620+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-5392;KEGG: 00630+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-7383;MetaCyc: PWY-561;KEGG: 00020+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00710+1.1.1.37;MetaCyc: PWY-5690;Reactome: R-HSA-70263;Reactome: R-HSA-71403;KEGG: 00720+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-5913 "Methylaspartate cycle";"Pyruvate metabolism";"Methane metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reductive TCA cycle II";"Glyoxylate and dicarboxylate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Formaldehyde assimilation I (serine pathway)";"Carbon fixation in photosynthetic organisms";"TCA cycle II (plants and fungi)";"Gluconeogenesis";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Cysteine and methionine metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)" JAMg_model_19962.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156827 "Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression" JAMg_model_14105.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_19491.2 4 Reactome: R-HSA-947581;Reactome: R-HSA-1362409;KEGG: 00730+2.8.1.7;MetaCyc: PWY-7250 "Molybdenum cofactor biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Thiamine metabolism";"[2Fe-2S] iron-sulfur cluster biosynthesis" JAMg_model_19712.1 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" JAMg_model_10407.4 3 Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" JAMg_model_16492.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" JAMg_model_2454.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" JAMg_model_16508.1 18 Reactome: R-HSA-69473;Reactome: R-HSA-5693616;MetaCyc: PWY-7511;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-1221632;Reactome: R-HSA-3108214;Reactome: R-HSA-5685938;Reactome: R-HSA-8953750;Reactome: R-HSA-6796648;Reactome: R-HSA-5693554;Reactome: R-HSA-5689901;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693565 "G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Protein ubiquitination";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"Meiotic synapsis";"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)";"Transcriptional Regulation by E2F6";"TP53 Regulates Transcription of DNA Repair Genes";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Metalloprotease DUBs";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" JAMg_model_13505.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" JAMg_model_733.1 6 Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-176187 "Assembly of the pre-replicative complex";"Unwinding of DNA";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress" JAMg_model_20032.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" JAMg_model_14606.1 6 MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" JAMg_model_3435.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-429958 "Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease" JAMg_model_1521.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-1268020 "Cristae formation";"Mitochondrial protein import" JAMg_model_8124.4 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" JAMg_model_8553.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_21325.3 1 Reactome: R-HSA-2024096 "HS-GAG degradation" JAMg_model_12130.4 24 Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220 "COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"HCMV Early Events";"Mitotic Prometaphase";"Kinesins";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"RHO GTPases Activate Formins" JAMg_model_7998.4 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" JAMg_model_11737.8 1 Reactome: R-HSA-400253 "Circadian Clock" JAMg_model_9184.6 6 MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis" JAMg_model_19615.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" JAMg_model_19209.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" JAMg_model_11733.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" JAMg_model_8107.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" JAMg_model_2063.2 30 Reactome: R-HSA-427413;Reactome: R-HSA-167160;Reactome: R-HSA-73776;Reactome: R-HSA-5696400;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73772;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-2564830;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-5696395;Reactome: R-HSA-6796648;Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-73863 "NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Promoter Escape";"Dual Incision in GG-NER";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Promoter Escape";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Cytosolic iron-sulfur cluster assembly";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of Incision Complex in GG-NER";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination" JAMg_model_4464.2 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" JAMg_model_11575.2 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" JAMg_model_12222.1 2 Reactome: R-HSA-1566948;Reactome: R-HSA-2243919 "Elastic fibre formation";"Crosslinking of collagen fibrils" JAMg_model_12473.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" JAMg_model_5945.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" JAMg_model_1770.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" JAMg_model_7186.2 18 MetaCyc: PWY-6642;KEGG: 00400+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-7115;MetaCyc: PWY-7117;KEGG: 00960+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-7383;KEGG: 00250+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00270+2.6.1.1;KEGG: 00401+2.6.1.1 "(R)-cysteate degradation";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Carbon fixation in photosynthetic organisms";"Arginine and proline metabolism";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"Phenylalanine metabolism";"Arginine biosynthesis";"Sulfolactate degradation III";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Coenzyme M biosynthesis II";"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine, aspartate and glutamate metabolism";"Partial TCA cycle (obligate autotrophs)";"Cysteine and methionine metabolism";"Novobiocin biosynthesis" JAMg_model_13226.2 3 KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I" JAMg_model_1709.1 3 Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5656121 "Translesion synthesis by POLK";"Translesion synthesis by REV1";"Translesion synthesis by POLI" JAMg_model_4893.3 12 KEGG: 00230+6.3.3.1;MetaCyc: PWY-6122;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;Reactome: R-HSA-196780;KEGG: 00230+6.3.4.13;KEGG: 00230+2.1.2.2;MetaCyc: PWY-6277;MetaCyc: PWY-6121;KEGG: 00670+2.1.2.2;Reactome: R-HSA-73817;MetaCyc: PWY-6613 "Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Biotin transport and metabolism";"Purine metabolism";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"One carbon pool by folate";"Purine ribonucleoside monophosphate biosynthesis";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate" JAMg_model_20343.1 3 Reactome: R-HSA-8963684;Reactome: R-HSA-156590;Reactome: R-HSA-204174 "Tyrosine catabolism";"Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex" JAMg_model_19199.5 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" JAMg_model_6069.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" JAMg_model_3157.1 4 KEGG: 00450+2.9.1.2;KEGG: 00970+2.9.1.2;MetaCyc: PWY-6281;Reactome: R-HSA-2408557 "Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis" JAMg_model_4123.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_3692.1 7 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection" JAMg_model_3077.1 33 Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-69202;Reactome: R-HSA-69231;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-75953;Reactome: R-HSA-73762;Reactome: R-HSA-6796648;Reactome: R-HSA-5696395;Reactome: R-HSA-167200;Reactome: R-HSA-69656;Reactome: R-HSA-6782135;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-72086;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-8939236;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-427413;Reactome: R-HSA-69273;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-167161 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Cyclin E associated events during G1/S transition";"Cyclin D associated events in G1";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of Incision Complex in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin A:Cdk2-associated events at S phase entry";"Dual incision in TC-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"mRNA Capping";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"NoRC negatively regulates rRNA expression";"Cyclin A/B1/B2 associated events during G2/M transition";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation" JAMg_model_17611.1 6 Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-176187 "Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress" JAMg_model_8013.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins" JAMg_model_20498.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_6074.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" JAMg_model_20068.2 5 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-917729;Reactome: R-HSA-193648;Reactome: R-HSA-9610379 "Rho GTPase cycle";"G alpha (12/13) signalling events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"NRAGE signals death through JNK";"HCMV Late Events" JAMg_model_6579.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-72163;Reactome: R-HSA-6811434 "Kinesins";"mRNA Splicing - Major Pathway";"COPI-dependent Golgi-to-ER retrograde traffic" JAMg_model_450.2 1 Reactome: R-HSA-8964038 "LDL clearance" JAMg_model_15875.3 1 Reactome: R-HSA-8949613 "Cristae formation" JAMg_model_10598.8 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5689880 "UCH proteinases";"Ub-specific processing proteases" JAMg_model_20772.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" JAMg_model_17518.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_13793.1 3 MetaCyc: PWY-7833;Reactome: R-HSA-9033807;MetaCyc: PWY-7831 "Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide" JAMg_model_16435.3 13 Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156827 "Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression" JAMg_model_750.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" JAMg_model_18296.1 7 MetaCyc: PWY-5941;Reactome: R-HSA-70221;MetaCyc: PWY-7238;Reactome: R-HSA-6798695;MetaCyc: PWY-6737;MetaCyc: PWY-6724;KEGG: 00500+2.4.1.25 "Glycogen degradation II";"Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II";"Neutrophil degranulation";"Starch degradation V";"Starch degradation II";"Starch and sucrose metabolism" JAMg_model_9300.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" JAMg_model_9948.2 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" JAMg_model_10811.2 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" JAMg_model_5073.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" JAMg_model_20391.2 4 KEGG: 00983+6.3.5.2;Reactome: R-HSA-73817;KEGG: 00230+6.3.5.2;MetaCyc: PWY-7221 "Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" JAMg_model_17785.6 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" JAMg_model_7597.1 8 Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68949 "CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin" JAMg_model_10411.1 1 Reactome: R-HSA-3000178 "ECM proteoglycans" JAMg_model_15215.1 3 Reactome: R-HSA-2514859;MetaCyc: PWY-7800;MetaCyc: PWY-7799 "Inactivation, recovery and regulation of the phototransduction cascade";"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)" JAMg_model_11736.2 4 KEGG: 00970+6.1.1.17;Reactome: R-HSA-379726;MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism" JAMg_model_3411.4 1 Reactome: R-HSA-977347 "Serine biosynthesis" JAMg_model_16816.4 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" JAMg_model_15692.1 5 Reactome: R-HSA-191273;Reactome: R-HSA-2426168;KEGG: 00900+2.7.4.2;MetaCyc: PWY-922;MetaCyc: PWY-7391 "Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)" JAMg_model_17090.1 19 Reactome: R-HSA-8964026;Reactome: R-HSA-8856828;Reactome: R-HSA-3000484;Reactome: R-HSA-3000471;Reactome: R-HSA-8856825;Reactome: R-HSA-202733;Reactome: R-HSA-8964038;Reactome: R-HSA-5686938;Reactome: R-HSA-8957275;Reactome: R-HSA-3000480;Reactome: R-HSA-8866423;Reactome: R-HSA-8963888;Reactome: R-HSA-432142;Reactome: R-HSA-381426;Reactome: R-HSA-975634;Reactome: R-HSA-8964046;Reactome: R-HSA-3000497;Reactome: R-HSA-8963901;Reactome: R-HSA-8964041 "Chylomicron clearance";"Clathrin-mediated endocytosis";"Scavenging by Class F Receptors";"Scavenging by Class B Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Cell surface interactions at the vascular wall";"LDL clearance";"Regulation of TLR by endogenous ligand";"Post-translational protein phosphorylation";"Scavenging by Class A Receptors";"VLDL assembly";"Chylomicron assembly";"Platelet sensitization by LDL";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Retinoid metabolism and transport";"VLDL clearance";"Scavenging by Class H Receptors";"Chylomicron remodeling";"LDL remodeling" JAMg_model_4961.3 5 Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360 "EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell" JAMg_model_8317.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" JAMg_model_14247.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_14840.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" JAMg_model_10598.2 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689603 "Ub-specific processing proteases";"UCH proteinases" JAMg_model_9987.1 4 Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813 "Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids" JAMg_model_247.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" JAMg_model_6612.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" JAMg_model_11705.2 6 MetaCyc: PWY-6124;MetaCyc: PWY-6123;KEGG: 00230+6.3.2.6;Reactome: R-HSA-73817;KEGG: 00230+4.1.1.21;MetaCyc: PWY-7234 "Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III" JAMg_model_11904.8 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" JAMg_model_16282.1 16 Reactome: R-HSA-179409;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-141430 "APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex" JAMg_model_2684.1 3 MetaCyc: PWY-6689;MetaCyc: PWY-7803;Reactome: R-HSA-6784531 "Trna splicing I";"Trna splicing II";"tRNA processing in the nucleus" JAMg_model_7374.2 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" JAMg_model_8098.3 1 Reactome: R-HSA-163841 "Gamma carboxylation, hypusine formation and arylsulfatase activation" JAMg_model_9047.4 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_6815.2 6 Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins" JAMg_model_4893.1 12 MetaCyc: PWY-6277;MetaCyc: PWY-6121;KEGG: 00670+2.1.2.2;MetaCyc: PWY-6613;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;KEGG: 00230+6.3.3.1;MetaCyc: PWY-6122;KEGG: 00230+6.3.4.13;Reactome: R-HSA-196780;KEGG: 00230+2.1.2.2 "Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"Biotin transport and metabolism";"Purine metabolism" JAMg_model_10118.1 1 Reactome: R-HSA-9022692 "Regulation of MECP2 expression and activity" JAMg_model_1164.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" JAMg_model_18918.9 3 MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268 "Methylglyoxal degradation I";"Pyruvate metabolism";"Pyruvate metabolism" JAMg_model_5374.1 1 Reactome: R-HSA-5626467 "RHO GTPases activate IQGAPs" JAMg_model_12967.1 4 MetaCyc: PWY-6483;MetaCyc: PWY-7119;Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23 "Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism";"Sphingolipid metabolism" JAMg_model_16858.4 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" JAMg_model_10024.2 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_4397.2 7 Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-165159 "Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"mTOR signalling" JAMg_model_8301.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733 "Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis" JAMg_model_5775.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" JAMg_model_10598.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5689880 "UCH proteinases";"Ub-specific processing proteases" JAMg_model_13381.3 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" JAMg_model_7362.5 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_19843.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_9200.6 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" JAMg_model_7752.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" JAMg_model_21356.1 9 Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-75953 "RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation" JAMg_model_19300.1 3 Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214 "DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins" JAMg_model_19795.1 4 KEGG: 00670+1.5.1.6;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;Reactome: R-HSA-196757 "One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Metabolism of folate and pterines" JAMg_model_6954.2 7 Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-5617472;Reactome: R-HSA-8953750;Reactome: R-HSA-8943724;Reactome: R-HSA-3214841;Reactome: R-HSA-2559580 "PRC2 methylates histones and DNA";"HCMV Early Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional Regulation by E2F6";"Regulation of PTEN gene transcription";"PKMTs methylate histone lysines";"Oxidative Stress Induced Senescence" JAMg_model_6625.2 4 Reactome: R-HSA-6790901;Reactome: R-HSA-156581;Reactome: R-HSA-6782315;Reactome: R-HSA-72764 "rRNA modification in the nucleus and cytosol";"Methylation";"tRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination" JAMg_model_872.3 4 MetaCyc: PWY-7807;Reactome: R-HSA-71737;MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1 "Glyphosate degradation III";"Pyrophosphate hydrolysis";"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation" JAMg_model_13503.3 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" JAMg_model_14067.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" JAMg_model_20269.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_1885.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" JAMg_model_20170.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" JAMg_model_3632.2 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" JAMg_model_11403.3 6 Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68867 "Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex" JAMg_model_20601.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" JAMg_model_19361.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_9291.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-9633012 "Viral mRNA Translation";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" JAMg_model_16024.1 4 Reactome: R-HSA-1614603;KEGG: 00270+4.2.1.22;MetaCyc: PWY-801;KEGG: 00260+4.2.1.22 "Cysteine formation from homocysteine";"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion";"Glycine, serine and threonine metabolism" JAMg_model_3756.2 6 MetaCyc: PWY-7817;MetaCyc: PWY-5269;MetaCyc: PWY-5668;Reactome: R-HSA-1483148;KEGG: 00564+2.7.8.5;Reactome: R-HSA-1483166 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis II";"Cardiolipin biosynthesis I";"Synthesis of PG";"Glycerophospholipid metabolism";"Synthesis of PA" JAMg_model_7498.1 10 KEGG: 00650+2.3.3.10;MetaCyc: PWY-7391;MetaCyc: PWY-7524;MetaCyc: PWY-6174;MetaCyc: PWY-7571;KEGG: 00280+2.3.3.10;MetaCyc: PWY-922;KEGG: 00072+2.3.3.10;Reactome: R-HSA-1989781;KEGG: 00900+2.3.3.10 "Butanoate metabolism";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Mevalonate pathway II (archaea)";"Ferrichrome A biosynthesis";"Valine, leucine and isoleucine degradation";"Mevalonate pathway I";"Synthesis and degradation of ketone bodies";"PPARA activates gene expression";"Terpenoid backbone biosynthesis" JAMg_model_18440.6 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" JAMg_model_14105.2 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_9790.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" JAMg_model_7039.1 3 Reactome: R-HSA-933542;Reactome: R-HSA-445989;Reactome: R-HSA-1810476 "TRAF6 mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"RIP-mediated NFkB activation via ZBP1" JAMg_model_12688.2 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_13588.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_17775.4 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" JAMg_model_18871.1 4 KEGG: 00513+2.4.1.257+2.4.1.132;KEGG: 00510+2.4.1.257+2.4.1.132;Reactome: R-HSA-446193;Reactome: R-HSA-4549349 "Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG2 causes ALG2-CDG (CDG-1i)" JAMg_model_12117.2 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" JAMg_model_14338.4 5 Reactome: R-HSA-432720;Reactome: R-HSA-6798695;KEGG: 00531+3.1.6.14;Reactome: R-HSA-2206305;Reactome: R-HSA-2022857 "Lysosome Vesicle Biogenesis";"Neutrophil degranulation";"Glycosaminoglycan degradation";"MPS IIID - Sanfilippo syndrome D";"Keratan sulfate degradation" JAMg_model_18830.1 10 KEGG: 00440+5.4.2.9;MetaCyc: PWY-5757;MetaCyc: PWY-7510;MetaCyc: PWY-6682;MetaCyc: PWY-6839;MetaCyc: PWY-7419;MetaCyc: PWY-6322;MetaCyc: PWY-8067;MetaCyc: PWY-7769;KEGG: 00998+5.4.2.9 "Phosphonate and phosphinate metabolism";"Fosfomycin biosynthesis";"Rhizocticin A and B biosynthesis";"Dehydrophos biosynthesis";"2-aminoethylphosphonate biosynthesis";"FR-900098 and FR-33289 antibiotics biosynthesis";"Phosphinothricin tripeptide biosynthesis";"Methylphosphonate biosynthesis";"Phosalacine biosynthesis";"Biosynthesis of various secondary metabolites - part 2" JAMg_model_6138.1 2 MetaCyc: PWY-6502;Reactome: R-HSA-2393930 "8-oxo-(d)GTP detoxification I";"Phosphate bond hydrolysis by NUDT proteins" JAMg_model_7346.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" JAMg_model_20866.5 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_5614.1 7 Reactome: R-HSA-3371453;Reactome: R-HSA-983170;Reactome: R-HSA-381183;Reactome: R-HSA-381042;Reactome: R-HSA-114608;Reactome: R-HSA-381070;Reactome: R-HSA-381033 "Regulation of HSF1-mediated heat shock response";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperone genes";"PERK regulates gene expression";"Platelet degranulation";"IRE1alpha activates chaperones";"ATF6 (ATF6-alpha) activates chaperones" JAMg_model_4808.2 2 Reactome: R-HSA-5689880;Reactome: R-HSA-8949215 "Ub-specific processing proteases";"Mitochondrial calcium ion transport" JAMg_model_2027.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" JAMg_model_4116.6 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" JAMg_model_8589.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5620912 "Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane" JAMg_model_19093.2 7 KEGG: 00970+6.1.1.17;Reactome: R-HSA-379716;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.15;Reactome: R-HSA-2408522;MetaCyc: PWY-5188;Reactome: R-HSA-6782315 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"tRNA modification in the nucleus and cytosol" JAMg_model_9592.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression" JAMg_model_15193.2 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_11241.1 10 Reactome: R-HSA-499943;MetaCyc: PWY-7210;MetaCyc: PWY-7199;KEGG: 00240+2.1.1.45;MetaCyc: PWY-7198;MetaCyc: PWY-7187;Reactome: R-HSA-69205;MetaCyc: PWY-3841;KEGG: 00670+2.1.1.45;MetaCyc: PWY-7184 "Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"G1/S-Specific Transcription";"Folate transformations II (plants)";"One carbon pool by folate";"Pyrimidine deoxyribonucleotides de novo biosynthesis I" JAMg_model_2896.1 5 Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-389957 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC" JAMg_model_21273.1 4 Reactome: R-HSA-1632852;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952 "Macroautophagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions" JAMg_model_5574.2 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" JAMg_model_4999.1 11 Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" JAMg_model_21130.2 6 Reactome: R-HSA-9033241;Reactome: R-HSA-9615017;Reactome: R-HSA-6798695;KEGG: 00630+1.11.1.6;Reactome: R-HSA-3299685;KEGG: 00380+1.11.1.6 "Peroxisomal protein import";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Neutrophil degranulation";"Glyoxylate and dicarboxylate metabolism";"Detoxification of Reactive Oxygen Species";"Tryptophan metabolism" JAMg_model_7345.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" JAMg_model_121.1 1 Reactome: R-HSA-156588 "Glucuronidation" JAMg_model_5138.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Peptide chain elongation" JAMg_model_14540.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" JAMg_model_8239.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" JAMg_model_1147.4 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" JAMg_model_18896.1 2 Reactome: R-HSA-196780;Reactome: R-HSA-3371599 "Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency" JAMg_model_17281.3 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_9797.3 1 Reactome: R-HSA-191273 "Cholesterol biosynthesis" JAMg_model_15268.4 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_16188.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" JAMg_model_21342.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_2420.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" JAMg_model_1632.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" JAMg_model_16905.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" JAMg_model_20788.1 9 Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events" JAMg_model_20787.13 32 Reactome: R-HSA-72203;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-6803529;Reactome: R-HSA-76042;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-73776;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-167172;Reactome: R-HSA-8851708;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167160;Reactome: R-HSA-72163;Reactome: R-HSA-168325;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-674695 "Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Promoter Escape";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"Transcription of the HIV genome";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Major Pathway";"Viral Messenger RNA Synthesis";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events" JAMg_model_2414.2 4 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion" JAMg_model_14171.2 5 Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656237;MetaCyc: PWY-6558 "Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT2 causes exostoses 2";"Heparan sulfate biosynthesis (late stages)" JAMg_model_15557.2 5 MetaCyc: PWY-4983;Reactome: R-HSA-1222556;KEGG: 00330+1.14.13.39;KEGG: 00220+1.14.13.39;Reactome: R-HSA-392154 "Nitric oxide biosynthesis II (mammals)";"ROS and RNS production in phagocytes";"Arginine and proline metabolism";"Arginine biosynthesis";"Nitric oxide stimulates guanylate cyclase" JAMg_model_9807.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" JAMg_model_12471.2 6 Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702 "Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition" JAMg_model_16566.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_11949.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" JAMg_model_2821.1 6 Reactome: R-HSA-114508;Reactome: R-HSA-1489509;Reactome: R-HSA-2029485;KEGG: 04070+2.7.11.13;Reactome: R-HSA-1250196;Reactome: R-HSA-418597 "Effects of PIP2 hydrolysis";"DAG and IP3 signaling";"Role of phospholipids in phagocytosis";"Phosphatidylinositol signaling system";"SHC1 events in ERBB2 signaling";"G alpha (z) signalling events" JAMg_model_15870.3 8 KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00524+2.7.1.1 "Streptomycin biosynthesis";"Starch and sucrose metabolism";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Neomycin, kanamycin and gentamicin biosynthesis" JAMg_model_17459.3 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" JAMg_model_16504.2 3 Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II" JAMg_model_5615.2 9 Reactome: R-HSA-193648;Reactome: R-HSA-2871796;Reactome: R-HSA-194840;Reactome: R-HSA-114604;Reactome: R-HSA-5218920;Reactome: R-HSA-2871809;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"FCERI mediated MAPK activation";"Rho GTPase cycle";"GPVI-mediated activation cascade";"VEGFR2 mediated vascular permeability";"FCERI mediated Ca+2 mobilization";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"G alpha (12/13) signalling events" JAMg_model_6601.3 1 Reactome: R-HSA-189200 "Cellular hexose transport" JAMg_model_21252.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" JAMg_model_19703.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis" JAMg_model_7423.3 1 Reactome: R-HSA-6799198 "Complex I biogenesis" JAMg_model_10973.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" JAMg_model_16203.1 2 Reactome: R-HSA-392154;Reactome: R-HSA-1222556 "Nitric oxide stimulates guanylate cyclase";"ROS and RNS production in phagocytes" JAMg_model_13845.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722 "NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex" JAMg_model_8515.2 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" JAMg_model_6844.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_6807.3 5 KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00720+4.2.1.3;KEGG: 00630+4.2.1.3 "Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)";"Iron uptake and transport";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism" JAMg_model_9895.7 10 MetaCyc: PWY-6317;MetaCyc: PWY-7344;MetaCyc: PWY-3821;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6527;Reactome: R-HSA-70370;MetaCyc: PWY-6397;Reactome: R-HSA-5609977;MetaCyc: PWY-7328;KEGG: 00520+5.1.3.2 "D-galactose degradation I (Leloir pathway)";"UDP-alpha-D-galactose biosynthesis";"D-galactose detoxification";"Galactose metabolism";"Stachyose degradation";"Galactose catabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Amino sugar and nucleotide sugar metabolism" JAMg_model_18051.2 2 Reactome: R-HSA-5689880;Reactome: R-HSA-110320 "Ub-specific processing proteases";"Translesion Synthesis by POLH" JAMg_model_7287.2 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" JAMg_model_2564.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" JAMg_model_15974.4 10 KEGG: 00710+2.7.2.3;MetaCyc: PWY-7003;Reactome: R-HSA-70171;Reactome: R-HSA-70263;MetaCyc: PWY-8004;MetaCyc: PWY-6886;KEGG: 00010+2.7.2.3;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-1042 "Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Glycolysis";"Gluconeogenesis";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)" JAMg_model_19983.4 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_14649.2 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" JAMg_model_19299.1 24 Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-190840 "Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane" JAMg_model_9200.4 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" JAMg_model_18681.3 1 KEGG: 00230+4.6.1.2 "Purine metabolism" JAMg_model_18133.3 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_10234.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_4976.1 7 MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7 "Justicidin B biosynthesis";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Betanidin degradation";"Phenylpropanoid biosynthesis" JAMg_model_9920.2 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" JAMg_model_12221.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" JAMg_model_17550.3 8 Reactome: R-HSA-8948747;Reactome: R-HSA-6781823;Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-8866652;Reactome: R-HSA-6782210 "Regulation of PTEN localization";"Formation of TC-NER Pre-Incision Complex";"Ub-specific processing proteases";"Regulation of TP53 Degradation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Gap-filling DNA repair synthesis and ligation in TC-NER" JAMg_model_19907.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" JAMg_model_17924.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" JAMg_model_1943.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" JAMg_model_17488.3 1 Reactome: R-HSA-611105 "Respiratory electron transport" JAMg_model_14765.2 3 Reactome: R-HSA-2995383;Reactome: R-HSA-4419969;Reactome: R-HSA-2980766 "Initiation of Nuclear Envelope Reformation";"Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown" JAMg_model_14841.2 31 MetaCyc: PWY-5147;MetaCyc: PWY-5989;Reactome: R-HSA-9029558;MetaCyc: PWY-7664;MetaCyc: PWY-5966-1;Reactome: R-HSA-75105;MetaCyc: PWY-5973;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-4381;MetaCyc: PWY-6113;MetaCyc: PWY-6282;MetaCyc: PWY-6799;MetaCyc: PWY-6519;MetaCyc: PWY-8012;Reactome: R-HSA-2426168;MetaCyc: PWYG-321;MetaCyc: PWY-7746;MetaCyc: PWY-5367;MetaCyc: PWY-5994;Reactome: R-HSA-199220;MetaCyc: PWY-7388;MetaCyc: PWY-5366;MetaCyc: PWY-7723;MetaCyc: PWY-7663;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5971;MetaCyc: PWY-7858;MetaCyc: PWY-8047;MetaCyc: PWY-8049;MetaCyc: PWY-5142;Reactome: R-HSA-163765 "Oleate biosynthesis I (plants)";"Stearate biosynthesis II (bacteria and plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acyl-CoA biosynthesis";"Cis-vaccenate biosynthesis";"Biotin metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Superpathway of mycolate biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis initiation (plant mitochondria)";"8-amino-7-oxononanoate biosynthesis I";"Mupirocin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"";"Mycobacterial sulfolipid biosynthesis";"Petroselinate biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitoleate biosynthesis II (plants and bacteria)";"Bacterial bioluminescence";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"(5Z)-dodecenoate biosynthesis II";"Bryostatin biosynthesis";"Pederin biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"ChREBP activates metabolic gene expression" JAMg_model_4160.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825 "Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis" JAMg_model_216.2 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" JAMg_model_12887.2 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" JAMg_model_13732.2 15 Reactome: R-HSA-2559585;Reactome: R-HSA-8853884;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-2559580;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593 "Oncogene Induced Senescence";"Transcriptional Regulation by VENTX";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity" JAMg_model_18566.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" JAMg_model_11842.1 17 Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-6790901;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72702 "L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition" JAMg_model_515.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" JAMg_model_3548.1 5 Reactome: R-HSA-6790901;KEGG: 00860+2.5.1.141;Reactome: R-HSA-189451;MetaCyc: PWY-7856;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Heme a biosynthesis";"Major pathway of rRNA processing in the nucleolus and cytosol" JAMg_model_9667.1 13 MetaCyc: PWY-7222;MetaCyc: PWY-7184;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7227;KEGG: 00230+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7220;MetaCyc: PWY-7210;MetaCyc: PWY-6545;Reactome: R-HSA-499943;KEGG: 00240+1.17.4.1 "Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism" JAMg_model_970.1 7 Reactome: R-HSA-5635838;Reactome: R-HSA-5658034;Reactome: R-HSA-5632684;Reactome: R-HSA-5362798;Reactome: R-HSA-5632681;Reactome: R-HSA-5358346;Reactome: R-HSA-373080 "Activation of SMO";"HHAT G278V abrogates palmitoylation of Hh-Np";"Hedgehog 'on' state";"Release of Hh-Np from the secreting cell";"Ligand-receptor interactions";"Hedgehog ligand biogenesis";"Class B/2 (Secretin family receptors)" JAMg_model_19054.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" JAMg_model_5067.1 1 Reactome: R-HSA-8949613 "Cristae formation" JAMg_model_6935.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" JAMg_model_1706.1 3 Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5656121 "Translesion synthesis by POLK";"Translesion synthesis by REV1";"Translesion synthesis by POLI" JAMg_model_4800.1 27 Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-159231 "ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript" JAMg_model_3074.1 2 Reactome: R-HSA-6803205;Reactome: R-HSA-8873719 "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation" JAMg_model_21165.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-1221632;Reactome: R-HSA-3108214;Reactome: R-HSA-2500257;Reactome: R-HSA-9018519 "Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Meiotic synapsis";"SUMOylation of DNA damage response and repair proteins";"Resolution of Sister Chromatid Cohesion";"Estrogen-dependent gene expression" JAMg_model_10882.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" JAMg_model_21049.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" JAMg_model_1290.1 56 Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-5687128;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684 "AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"UCH proteinases";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"MAPK6/MAPK4 signaling";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state" JAMg_model_2007.2 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" JAMg_model_16720.1 2 Reactome: R-HSA-2142691;Reactome: R-HSA-2142700 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)" JAMg_model_5572.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" JAMg_model_887.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" JAMg_model_8910.3 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" JAMg_model_15135.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" JAMg_model_17711.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518 "Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2" JAMg_model_12920.2 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" JAMg_model_1169.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" JAMg_model_13843.1 5 KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00600+3.2.1.22 "Glycerolipid metabolism";"Galactose metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Sphingolipid metabolism" JAMg_model_17489.2 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" JAMg_model_18024.4 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" JAMg_model_4466.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" JAMg_model_5092.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" JAMg_model_10136.1 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" JAMg_model_2084.1 11 Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-9013695;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2173796;Reactome: R-HSA-72163 "Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"mRNA Splicing - Major Pathway" JAMg_model_18671.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" JAMg_model_14959.1 6 Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556 "Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Neutrophil degranulation";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes" JAMg_model_19028.4 1 Reactome: R-HSA-8951664 "Neddylation" JAMg_model_7576.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" JAMg_model_18869.2 3 KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9;Reactome: R-HSA-5368286 "Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"Mitochondrial translation initiation" JAMg_model_21267.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" JAMg_model_9494.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" JAMg_model_11737.9 1 Reactome: R-HSA-400253 "Circadian Clock" JAMg_model_3358.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72689 "SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits" JAMg_model_9858.1 5 Reactome: R-HSA-381183;Reactome: R-HSA-380994;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168 "ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)" JAMg_model_13397.1 7 MetaCyc: PWY-7782;Reactome: R-HSA-1483191;MetaCyc: PWY-3385;Reactome: R-HSA-1483213;MetaCyc: PWY-7886;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7818 "Plasmalogen biosynthesis";"Synthesis of PC";"Choline biosynthesis I";"Synthesis of PE";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Glycerophospholipid metabolism";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)" JAMg_model_16556.1 5 KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-6855 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)" JAMg_model_7222.1 16 Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-983168;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-9010553;Reactome: R-HSA-167152 "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Neddylation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Antigen processing: Ubiquitination & Proteasome degradation";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Regulation of expression of SLITs and ROBOs";"Formation of HIV elongation complex in the absence of HIV Tat" JAMg_model_1147.3 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" JAMg_model_12121.3 6 KEGG: 00564+1.1.5.3;MetaCyc: PWY-6952;Reactome: R-HSA-163560;MetaCyc: PWY-4261;Reactome: R-HSA-1483166;MetaCyc: PWY-6118 "Glycerophospholipid metabolism";"Glycerophosphodiester degradation";"Triglyceride catabolism";"Glycerol degradation I";"Synthesis of PA";"Glycerol-3-phosphate shuttle" JAMg_model_738.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" JAMg_model_20399.1 8 KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTOR signaling pathway";"PI3K-Akt signaling pathway" JAMg_model_7830.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661 "Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis" JAMg_model_17402.1 1 Reactome: R-HSA-264876 "Insulin processing" JAMg_model_12984.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" JAMg_model_5695.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" JAMg_model_17283.7 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" JAMg_model_14484.1 5 Reactome: R-HSA-1266695;Reactome: R-HSA-3214858;Reactome: R-HSA-201722;Reactome: R-HSA-8939243;Reactome: R-HSA-3247509 "Interleukin-7 signaling";"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Chromatin modifying enzymes" JAMg_model_4185.3 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" JAMg_model_16399.1 4 Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" JAMg_model_20780.1 57 Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-4641257 "Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN" JAMg_model_8092.2 1 Reactome: R-HSA-5620924 "Intraflagellar transport" JAMg_model_6466.1 26 Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-389977;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-389960;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436 "RHO GTPases Activate Formins";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"Post-chaperonin tubulin folding pathway";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"Kinesins";"Formation of tubulin folding intermediates by CCT/TriC";"Mitotic Prometaphase";"HCMV Early Events";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic" JAMg_model_6940.1 15 KEGG: 00010+2.7.1.40;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-1042;MetaCyc: PWY-7383;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-2221;MetaCyc: PWY-8004;MetaCyc: PWY-6886;MetaCyc: PWY-5723;Reactome: R-HSA-70171;MetaCyc: PWY-7003;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6142 "Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Purine metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Rubisco shunt";"Glycolysis";"Glycerol degradation to butanol";"Pyruvate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" JAMg_model_238.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" JAMg_model_16407.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" JAMg_model_19986.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" JAMg_model_1971.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" JAMg_model_17536.2 3 Reactome: R-HSA-3214847;Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "HATs acetylate histones";"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" JAMg_model_17208.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" JAMg_model_6621.2 25 Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-380270;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-983189;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276 "COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of mitotic centrosome proteins and complexes";"Aggrephagy";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"Mitotic Prometaphase";"HCMV Early Events";"Kinesins";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint" JAMg_model_19012.2 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" JAMg_model_19551.3 6 MetaCyc: PWY-7426;Reactome: R-HSA-975578;Reactome: R-HSA-4793952;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143 "Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis" JAMg_model_628.2 6 MetaCyc: PWY-2221;MetaCyc: PWY-7165;KEGG: 00030+3.1.1.17;KEGG: 00930+3.1.1.17;MetaCyc: PWY-5530;KEGG: 00053+3.1.1.17 "Entner-Doudoroff pathway III (semi-phosphorylative)";"L-ascorbate biosynthesis VI (engineered pathway)";"Pentose phosphate pathway";"Caprolactam degradation";"Sorbitol biosynthesis II";"Ascorbate and aldarate metabolism" JAMg_model_18340.2 9 MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52 "Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series" JAMg_model_5848.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" JAMg_model_258.1 5 Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-5610787;Reactome: R-HSA-5610785 "Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Hedgehog 'off' state";"GLI3 is processed to GLI3R by the proteasome" JAMg_model_2589.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" JAMg_model_619.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" JAMg_model_1018.1 16 Reactome: R-HSA-5603041;Reactome: R-HSA-1810476;Reactome: R-HSA-9020702;Reactome: R-HSA-166058;Reactome: R-HSA-975155;Reactome: R-HSA-1236974;Reactome: R-HSA-209543;Reactome: R-HSA-1257604;Reactome: R-HSA-975871;Reactome: R-HSA-5602498;Reactome: R-HSA-6811558;Reactome: R-HSA-5602680;Reactome: R-HSA-5603037;Reactome: R-HSA-975138;Reactome: R-HSA-3134963;Reactome: R-HSA-975110 "IRAK4 deficiency (TLR2/4)";"RIP-mediated NFkB activation via ZBP1";"Interleukin-1 signaling";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 dependent cascade initiated on endosome";"ER-Phagosome pathway";"p75NTR recruits signalling complexes";"PIP3 activates AKT signaling";"MyD88 cascade initiated on plasma membrane";"MyD88 deficiency (TLR2/4)";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"MyD88 deficiency (TLR5)";"IRAK4 deficiency (TLR5)";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling" JAMg_model_10407.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-8876198 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs" JAMg_model_17127.1 17 MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-8041;Reactome: R-HSA-5419276;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7035;Reactome: R-HSA-5389840;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7602;Reactome: R-HSA-5368286;MetaCyc: PWY-5080 "Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Mitochondrial translation termination";"Juniperonate biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Mitochondrial translation elongation";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Mitochondrial translation initiation";"Very long chain fatty acid biosynthesis I"