Accession_ID Pathway_Count Pathway_IDs Pathway_Names XP_037815688.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037810680.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037816207.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037828775.1 1 Reactome: R-HSA-446203 "Asparagine N-linked glycosylation" XP_037809707.1 6 KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107 "Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism" XP_037811624.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_037818155.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037826840.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_037821935.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_037816035.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037813224.1 10 Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932;Reactome: R-HSA-451308;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-447038;Reactome: R-HSA-399719 "RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Synaptic adhesion-like molecules";"Activation of Ca-permeable Kainate Receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"NrCAM interactions";"Trafficking of AMPA receptors" XP_037805519.1 3 Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007 "Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy" XP_037822369.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_037808759.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037809451.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037816852.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037821252.1 5 Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-390450 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC" XP_037809557.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037826372.1 14 Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2565942;Reactome: R-HSA-2467813;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-380284 "Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of PLK1 Activity at G2/M Transition";"Separation of Sister Chromatids";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_037818195.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037813092.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037805689.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037818538.1 4 Reactome: R-HSA-6799198;Reactome: R-HSA-77289;Reactome: R-HSA-611105;Reactome: R-HSA-389661 "Complex I biogenesis";"Mitochondrial Fatty Acid Beta-Oxidation";"Respiratory electron transport";"Glyoxylate metabolism and glycine degradation" XP_037815888.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_037814210.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037825299.1 3 Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161 "Metabolism of folate and pterines";"Folate biosynthesis";"Folate polyglutamylation" XP_037805463.1 27 Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-3371453 "Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response" XP_037810524.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037806815.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_037825040.1 4 MetaCyc: PWY-6483;Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119 "Ceramide degradation (generic)";"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)" XP_037806120.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_037814849.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-1358803;Reactome: R-HSA-983168 "Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037820629.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037811619.1 5 Reactome: R-HSA-109704;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530 "PI3K Cascade";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer" XP_037813090.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037816165.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037825158.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_037827103.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_037828708.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_037812986.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037825187.1 3 Reactome: R-HSA-1474228;Reactome: R-HSA-1592389;Reactome: R-HSA-1442490 "Degradation of the extracellular matrix";"Activation of Matrix Metalloproteinases";"Collagen degradation" XP_037817319.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037814406.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_037807599.1 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_037828571.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037827841.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_037815140.1 5 Reactome: R-HSA-165181;Reactome: R-HSA-380972;Reactome: R-HSA-8854214;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897 "Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK";"TBC/RABGAPs";"Macroautophagy";"TP53 Regulates Metabolic Genes" XP_037821352.1 3 KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II" XP_037822666.1 5 Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-8856825;Reactome: R-HSA-2173789;Reactome: R-HSA-917937 "Neddylation";"UCH proteinases";"Cargo recognition for clathrin-mediated endocytosis";"TGF-beta receptor signaling activates SMADs";"Iron uptake and transport" XP_037805467.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037815643.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_037817452.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" XP_037811563.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037810715.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_037825661.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7802 "Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)" XP_037825239.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037821110.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_037818577.1 6 KEGG: 04658+3.1.3.16;Reactome: R-HSA-5693565;KEGG: 05235+3.1.3.16;Reactome: R-HSA-8939211;Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"ESR-mediated signaling";"Negative regulation of MAPK pathway";"T cell receptor signaling pathway" XP_037807440.1 4 Reactome: R-HSA-1483191;KEGG: 00564+3.1.1.7;Reactome: R-HSA-112311;Reactome: R-HSA-422085 "Synthesis of PC";"Glycerophospholipid metabolism";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin" XP_037820388.1 5 MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109 "Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis" XP_037811348.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037815241.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037815723.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_037823828.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037813527.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_037817388.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037826734.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_037824644.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037816943.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037822674.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_037813792.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_037808771.1 4 KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943 "Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_037818567.1 11 Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-68962;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-174430;Reactome: R-HSA-5696400;Reactome: R-HSA-68952 "Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Telomere C-strand synthesis initiation";"Dual Incision in GG-NER";"DNA replication initiation" XP_037817301.1 4 MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847 "Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis";"UCH proteinases";"HATs acetylate histones" XP_037806767.1 7 KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis" XP_037816410.1 2 Reactome: R-HSA-446193;Reactome: R-HSA-4549349 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG2 causes ALG2-CDG (CDG-1i)" XP_037814549.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037821107.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_037819970.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037823197.1 6 Reactome: R-HSA-381426;Reactome: R-HSA-5626467;Reactome: R-HSA-8957275;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2173796 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"RHO GTPases activate IQGAPs";"Post-translational protein phosphorylation";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription" XP_037825060.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_037814813.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_037810589.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037811029.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037821157.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037814738.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037810337.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_037817475.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037818596.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_037827152.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_037812409.1 4 Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163 "Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway" XP_037817047.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037815598.1 12 KEGG: 00500+2.7.7.9;KEGG: 00040+2.7.7.9;KEGG: 00052+2.7.7.9;MetaCyc: PWY-3801;KEGG: 00561+2.7.7.9;Reactome: R-HSA-3322077;MetaCyc: PWY-7343;Reactome: R-HSA-173599;KEGG: 00520+2.7.7.9;MetaCyc: PWY-6527;MetaCyc: PWY-7238;MetaCyc: PWY-7817 "Starch and sucrose metabolism";"Pentose and glucuronate interconversions";"Galactose metabolism";"Sucrose degradation II (sucrose synthase)";"Glycerolipid metabolism";"Glycogen synthesis";"UDP-alpha-D-glucose biosynthesis I";"Formation of the active cofactor, UDP-glucuronate";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Sucrose biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_037821216.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037824882.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_037806787.1 7 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway" XP_037825515.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_037808469.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265 "NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes" XP_037805493.1 4 KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737;MetaCyc: PWY-6922;Reactome: R-HSA-70688 "Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Proline catabolism" XP_037825285.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037825442.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_037825868.1 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_037828086.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_037813108.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037806333.1 14 MetaCyc: PWY-7619;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7036 "Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II" XP_037808751.1 9 MetaCyc: PWY-6142;Reactome: R-HSA-1475029;MetaCyc: PWY-5744;MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle" XP_037814240.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037806293.1 29 Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-73863;Reactome: R-HSA-6782210;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-6781823;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-73772;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-167161;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-113418 "RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Termination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation";"Dual incision in TC-NER";"Transcription of the HIV genome";"Formation of the Early Elongation Complex" XP_037822557.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037820919.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_037810467.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase" XP_037817673.1 4 Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090 "Collagen degradation";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures" XP_037810216.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_037814051.1 42 MetaCyc: PWY-5177;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;MetaCyc: PWY-7606;MetaCyc: PWY-5138;KEGG: 00410+4.2.1.17;MetaCyc: PWY-6883;MetaCyc: PWY-5789;MetaCyc: PWY-7216;MetaCyc: PWY-7401;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7656;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;MetaCyc: PWY-6863;MetaCyc: PWY-1361;MetaCyc: PWY-6944;MetaCyc: PWY-7779;KEGG: 00592+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;MetaCyc: PWY-5109;KEGG: 00903+4.2.1.17;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7007;KEGG: 00360+4.2.1.17;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;MetaCyc: PWY-7094;MetaCyc: PWY-6435;KEGG: 00623+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583 "Glutaryl-coa degradation";"Benzoate degradation";"Carbon fixation pathways in prokaryotes";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"beta-Alanine metabolism";"Pyruvate fermentation to butanol II (engineered)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Aminobenzoate degradation";"Spodoptera littoralis pheromone biosynthesis";"Caprolactam degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Pyruvate fermentation to hexanol (engineered)";"Benzoyl-coa degradation I (aerobic)";"Androstenedione degradation";"Methyl tert-butyl ether degradation";"alpha-Linolenic acid metabolism";"Valine, leucine and isoleucine degradation";"Butanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fermentation to 2-methylbutanoate";"Limonene and pinene degradation";"Propanoate metabolism";"Methyl ketone biosynthesis (engineered)";"Phenylalanine metabolism";"Butanoate metabolism";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fatty acid elongation";"Fatty acid degradation";"Geraniol degradation";"Fatty acid degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Tryptophan metabolism";"2-methylpropene degradation";"Fatty acid salvage";"4-hydroxybenzoate biosynthesis III (plants)";"Toluene degradation";"Lysine degradation";"Pyruvate fermentation to butanol I" XP_037812391.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037811627.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_037816694.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_037819303.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037809656.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037827874.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_037819084.1 3 Reactome: R-HSA-9609523;Reactome: R-HSA-1236974;Reactome: R-HSA-1799339 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane" XP_037827951.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037822584.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_037805371.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_037817275.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037826318.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037807128.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037821605.1 12 Reactome: R-HSA-76071;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-76066;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-73772;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_037817535.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_037823433.1 11 Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-2644606;Reactome: R-HSA-1251985;Reactome: R-HSA-193692;Reactome: R-HSA-2894862;Reactome: R-HSA-3928665;Reactome: R-HSA-9013700;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-9017802 "NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nuclear signaling by ERBB4";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3" XP_037820099.1 6 MetaCyc: PWY-5514;MetaCyc: PWY-6749;KEGG: 00520+5.4.2.3;KEGG: 00520+5.4.2.10;MetaCyc: PWY-6906;Reactome: R-HSA-446210 "UDP-N-acetyl-D-galactosamine biosynthesis II";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine" XP_037810245.1 2 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol" XP_037811552.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_037805552.1 11 Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-5689880;Reactome: R-HSA-3214847;Reactome: R-HSA-167161;Reactome: R-HSA-167172 "RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"Ub-specific processing proteases";"HATs acetylate histones";"HIV Transcription Initiation";"Transcription of the HIV genome" XP_037805807.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450604 "Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA" XP_037819839.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_037805580.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_037812041.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_037806987.1 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097 "T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway" XP_037814269.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037823183.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_037815432.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037806036.1 6 MetaCyc: PWY-7900;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067;Reactome: R-HSA-3878781;Reactome: R-HSA-3322077 "Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen storage disease type IV (GBE1)";"Glycogen synthesis" XP_037822337.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_037808030.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037819931.1 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" XP_037818720.1 9 KEGG: 00564+1.1.1.8;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-5667;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7902;MetaCyc: PWY-6118;MetaCyc: PWY-7385 "Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis";"Glycerol-3-phosphate shuttle";"1,3-propanediol biosynthesis (engineered)" XP_037822191.1 2 Reactome: R-HSA-2206307;Reactome: R-HSA-2024096 "MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation" XP_037810080.1 7 KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis" XP_037810356.1 14 Reactome: R-HSA-6811436;Reactome: R-HSA-5620924;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-1632852;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-141444 "COPI-independent Golgi-to-ER retrograde traffic";"Intraflagellar transport";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Macroautophagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_037821060.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_037806468.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection" XP_037811392.1 14 Reactome: R-HSA-9013507;Reactome: R-HSA-6798695;Reactome: R-HSA-2894862;Reactome: R-HSA-193692;Reactome: R-HSA-1251985;Reactome: R-HSA-205043;Reactome: R-HSA-2644606;Reactome: R-HSA-977225;Reactome: R-HSA-3928665;Reactome: R-HSA-9013700;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-1474228;Reactome: R-HSA-9017802 "NOTCH3 Activation and Transmission of Signal to the Nucleus";"Neutrophil degranulation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulated proteolysis of p75NTR";"Nuclear signaling by ERBB4";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Amyloid fiber formation";"EPH-ephrin mediated repulsion of cells";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Degradation of the extracellular matrix";"Noncanonical activation of NOTCH3" XP_037805410.1 11 Reactome: R-HSA-9664565;Reactome: R-HSA-8863795;Reactome: R-HSA-8847993;Reactome: R-HSA-6785631;Reactome: R-HSA-6811558;Reactome: R-HSA-1963642;Reactome: R-HSA-1257604;Reactome: R-HSA-1227986;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-1250196 "Signaling by ERBB2 KD Mutants";"Downregulation of ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"ERBB2 Regulates Cell Motility";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K events in ERBB2 signaling";"PIP3 activates AKT signaling";"Signaling by ERBB2";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC1 events in ERBB2 signaling" XP_037811717.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_037823474.1 4 KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188;Reactome: R-HSA-379726 "Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Mitochondrial tRNA aminoacylation" XP_037816912.1 5 Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920 "Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability" XP_037817421.1 8 Reactome: R-HSA-1222556;Reactome: R-HSA-167590;Reactome: R-HSA-917977;Reactome: R-HSA-182218;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-9636467 "ROS and RNS production in phagocytes";"Nef Mediated CD4 Down-regulation";"Transferrin endocytosis and recycling";"Nef Mediated CD8 Down-regulation";"Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Blockage of phagosome acidification" XP_037805632.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_037810973.1 3 Reactome: R-HSA-2024101;Reactome: R-HSA-2206302;Reactome: R-HSA-2024096 "CS/DS degradation";"MPS I - Hurler syndrome";"HS-GAG degradation" XP_037817504.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037824718.1 20 Reactome: R-HSA-5218920;Reactome: R-HSA-3371571;Reactome: R-HSA-5628897;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 04926+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04714+2.7.11.1;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-1257604;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9639288;Reactome: R-HSA-165159 "VEGFR2 mediated vascular permeability";"HSF1-dependent transactivation";"TP53 Regulates Metabolic Genes";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Macroautophagy";"Relaxin signaling pathway";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Thermogenesis";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"PIP3 activates AKT signaling";"Human cytomegalovirus infection";"Amino acids regulate mTORC1";"mTOR signalling" XP_037826118.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_037815709.1 5 KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317 "Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose detoxification";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)" XP_037806658.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation" XP_037819887.1 9 MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-7117;MetaCyc: PWY-5743;MetaCyc: PWY-7115;MetaCyc: PWY-5744;Reactome: R-HSA-1475029;MetaCyc: PWY-6142 "3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"Reversible hydration of carbon dioxide";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_037815755.1 11 KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-5610787 "Purine metabolism";"G alpha (z) signalling events";"PKA activation";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state" XP_037818703.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597 "Hedgehog 'off' state";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"PKA activation";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (z) signalling events" XP_037818743.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037815622.1 11 Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-163359 "Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Hedgehog 'off' state";"Purine metabolism";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"PKA activation";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation" XP_037822773.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037823056.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_037814122.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037807281.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037806817.1 3 Reactome: R-HSA-6804760;Reactome: R-HSA-2299718;Reactome: R-HSA-3214841 "Regulation of TP53 Activity through Methylation";"Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines" XP_037827273.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037821767.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037824337.1 2 Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3 "Platelet degranulation";"Aminoacyl-tRNA biosynthesis" XP_037806250.1 11 Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-170670 "Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Hedgehog 'off' state";"Purine metabolism";"G alpha (z) signalling events";"G alpha (i) signalling events";"PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway" XP_037812240.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_037825183.1 1 Reactome: R-HSA-446193 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_037810002.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956 "Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Peptide chain elongation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_037825161.1 5 MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_037814405.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_037814918.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_037818102.1 4 Reactome: R-HSA-156581;MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041 "Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_037824874.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_037819929.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_037805483.1 3 Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007 "Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy" XP_037825163.1 9 Reactome: R-HSA-68689;Reactome: R-HSA-1362277;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-69205;Reactome: R-HSA-68962;Reactome: R-HSA-69017;Reactome: R-HSA-68827;Reactome: R-HSA-176187 "CDC6 association with the ORC:origin complex";"Transcription of E2F targets under negative control by DREAM complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"G1/S-Specific Transcription";"Activation of the pre-replicative complex";"CDK-mediated phosphorylation and removal of Cdc6";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress" XP_037809624.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037823759.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-450513 "mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_037816680.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037806435.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_037819796.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037817183.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037807649.1 6 Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68867 "Unwinding of DNA";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex" XP_037808905.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_037821277.1 4 KEGG: 00510+2.4.1.131;Reactome: R-HSA-4551295;KEGG: 00513+2.4.1.131;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_037821661.1 1 Reactome: R-HSA-379716 "Cytosolic tRNA aminoacylation" XP_037808768.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037806429.1 22 Reactome: R-HSA-5358749;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-5675221;Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-4641262;Reactome: R-HSA-141444;Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-2500257;Reactome: R-HSA-5358751;Reactome: R-HSA-432142;Reactome: R-HSA-9648025;Reactome: R-HSA-6811558;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-5673000;Reactome: R-HSA-196299;Reactome: R-HSA-5467340 "S37 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"Resolution of Sister Chromatid Cohesion";"S45 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"EML4 and NUDC in mitotic spindle formation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"RAF activation";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex" XP_037816354.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_037807122.1 4 Reactome: R-HSA-352230;Reactome: R-HSA-71240;Reactome: R-HSA-210991;Reactome: R-HSA-5660862 "Amino acid transport across the plasma membrane";"Tryptophan catabolism";"Basigin interactions";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)" XP_037806845.1 15 MetaCyc: PWY-8004;MetaCyc: PWY-2221;MetaCyc: PWY-7383;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-6886;MetaCyc: PWY-5484;KEGG: 00620+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-6142;MetaCyc: PWY-5723;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6901;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7218 "Entner-Doudoroff pathway I";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis";"Glycerol degradation to butanol";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Pyruvate metabolism";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Rubisco shunt";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Purine metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)" XP_037815602.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037818284.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_037811639.1 4 Reactome: R-HSA-70895;MetaCyc: PWY-5642;KEGG: 00280+1.2.1.27;KEGG: 00640+1.2.1.27 "Branched-chain amino acid catabolism";"2,4-dinitrotoluene degradation";"Valine, leucine and isoleucine degradation";"Propanoate metabolism" XP_037805318.1 5 MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921 "Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)" XP_037819348.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037813385.1 2 Reactome: R-HSA-446193;Reactome: R-HSA-5633231 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)" XP_037805368.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_037818997.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037807559.1 4 Reactome: R-HSA-3000178;Reactome: R-HSA-2129379;Reactome: R-HSA-216083;Reactome: R-HSA-3000170 "ECM proteoglycans";"Molecules associated with elastic fibres";"Integrin cell surface interactions";"Syndecan interactions" XP_037828267.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037821267.1 18 Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-166208;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-1799339 "Translation initiation complex formation";"Peptide chain elongation";"Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"mTORC1-mediated signalling";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane" XP_037814952.1 5 Reactome: R-HSA-1660662;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-4085001;Reactome: R-HSA-4341670 "Glycosphingolipid metabolism";"Neutrophil degranulation";"MHC class II antigen presentation";"Sialic acid metabolism";"Defective NEU1 causes sialidosis" XP_037820270.1 6 KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817 "Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_037813763.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_037817543.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-2408557 "Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis" XP_037828167.1 7 Reactome: R-HSA-9020265;Reactome: R-HSA-6798695;Reactome: R-HSA-2142691;Reactome: R-HSA-9018676;Reactome: R-HSA-9023661;Reactome: R-HSA-9018896;Reactome: R-HSA-9018681 "Biosynthesis of aspirin-triggered D-series resolvins";"Neutrophil degranulation";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Biosynthesis of D-series resolvins";"Biosynthesis of E-series 18(R)-resolvins";"Biosynthesis of E-series 18(S)-resolvins";"Biosynthesis of protectins" XP_037808787.1 2 KEGG: 00230+4.6.1.1;Reactome: R-HSA-196819 "Purine metabolism";"Vitamin B1 (thiamin) metabolism" XP_037826122.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037828276.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_037809989.1 5 Reactome: R-HSA-197264;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21 "Nicotinamide salvaging";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism" XP_037810486.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025 "Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation" XP_037819600.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_037817037.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037817805.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_037810519.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037808913.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-450513 "ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_037828631.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_037807694.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-190873 "Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Gap junction degradation" XP_037812615.1 4 Reactome: R-HSA-983231;Reactome: R-HSA-2586552;Reactome: R-HSA-982772;Reactome: R-HSA-1170546 "Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin";"Growth hormone receptor signaling";"Prolactin receptor signaling" XP_037819498.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-983231 "Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production" XP_037821197.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037806628.1 8 Reactome: R-HSA-180024;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-983231;Reactome: R-HSA-163615;Reactome: R-HSA-381676;Reactome: R-HSA-442720 "DARPP-32 events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production";"PKA activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase" XP_037809103.1 6 MetaCyc: PWY-5484;KEGG: 00010+5.4.2.11;KEGG: 00680+5.4.2.11;MetaCyc: PWY-8004;KEGG: 00260+5.4.2.11;MetaCyc: PWY-1622 "Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Entner-Doudoroff pathway I";"Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)" XP_037827937.1 6 Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway" XP_037819601.1 2 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_037816186.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_037806861.1 7 KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway" XP_037813670.1 7 Reactome: R-HSA-381070;Reactome: R-HSA-114608;Reactome: R-HSA-381042;Reactome: R-HSA-3371453;Reactome: R-HSA-381183;Reactome: R-HSA-983170;Reactome: R-HSA-381033 "IRE1alpha activates chaperones";"Platelet degranulation";"PERK regulates gene expression";"Regulation of HSF1-mediated heat shock response";"ATF6 (ATF6-alpha) activates chaperone genes";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperones" XP_037812173.1 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_037826586.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_037819266.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_037821085.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037824614.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72706 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Viral mRNA Translation";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037805782.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037813544.1 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" XP_037812775.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037826781.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_037826011.1 6 MetaCyc: PWY-8004;KEGG: 00030+3.1.1.31;MetaCyc: PWY-6855;MetaCyc: PWY-5514;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906 "Entner-Doudoroff pathway I";"Pentose phosphate pathway";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation" XP_037820245.1 5 Reactome: R-HSA-6811438;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network" XP_037811466.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037812052.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_037826356.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_037812136.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037821427.1 9 KEGG: 00270+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00130+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00401+2.6.1.5;KEGG: 00400+2.6.1.5 "Cysteine and methionine metabolism";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"Phenylalanine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Tyrosine catabolism";"Novobiocin biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis" XP_037814264.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037828859.1 8 Reactome: R-HSA-373080;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900;Reactome: R-HSA-4641263;Reactome: R-HSA-4608870;Reactome: R-HSA-4086398;Reactome: R-HSA-5340588 "Class B/2 (Secretin family receptors)";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Regulation of FZD by ubiquitination";"Asymmetric localization of PCP proteins";"Ca2+ pathway";"RNF mutants show enhanced WNT signaling and proliferation" XP_037827436.1 11 KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-5610787 "Purine metabolism";"G alpha (z) signalling events";"G alpha (i) signalling events";"PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Hedgehog 'off' state" XP_037828625.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_037818378.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037815115.1 5 MetaCyc: PWY-5981;KEGG: 04070+2.7.7.41;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5667;MetaCyc: PWY-7817 "CDP-diacylglycerol biosynthesis III";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_037816161.1 14 MetaCyc: PWY-7587;MetaCyc: PWY-8055;Reactome: R-HSA-9018519;Reactome: R-HSA-8931987;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-8053;Reactome: R-HSA-2426168;KEGG: 00564+2.3.1.15;Reactome: R-HSA-75109;MetaCyc: PWY-8051;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15 "Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Estrogen-dependent gene expression";"RUNX1 regulates estrogen receptor mediated transcription";"Synthesis of PA";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Activation of gene expression by SREBF (SREBP)";"Glycerophospholipid metabolism";"Triglyceride biosynthesis";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism" XP_037813920.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_037815568.1 5 Reactome: R-HSA-68827;Reactome: R-HSA-69205;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962 "CDT1 association with the CDC6:ORC:origin complex";"G1/S-Specific Transcription";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex" XP_037826885.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" XP_037823751.1 16 MetaCyc: PWY-6142;MetaCyc: PWY-1622;KEGG: 00680+4.2.1.11;MetaCyc: PWY-6901;Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-7003;MetaCyc: PWY-7218;KEGG: 00010+4.2.1.11;MetaCyc: PWY-5723;MetaCyc: PWY-7124;MetaCyc: PWY-8004;Reactome: R-HSA-70171;MetaCyc: PWY-2221;MetaCyc: PWY-6886;MetaCyc: PWY-1042 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Superpathway of glucose and xylose degradation";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Rubisco shunt";"Ethylene biosynthesis V (engineered)";"Entner-Doudoroff pathway I";"Glycolysis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)" XP_037822177.1 6 MetaCyc: PWY-922;KEGG: 00900+2.7.1.36;Reactome: R-HSA-2426168;MetaCyc: PWY-6174;Reactome: R-HSA-191273;MetaCyc: PWY-7391 "Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway II (archaea)";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)" XP_037827641.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037809671.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037823129.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_037825401.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_037811396.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_037821449.1 19 Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-5673000;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-9022692;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-9617324 "Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"RAF activation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling downstream of RAS mutants";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion transport by P-type ATPases";"Interferon gamma signaling";"HSF1-dependent transactivation";"Regulation of MECP2 expression and activity";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_037813893.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_037816489.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_037819756.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_037820997.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_037826555.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037821538.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037806283.1 3 Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546 "Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)" XP_037824436.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957 "Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_037822677.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_037820504.1 8 Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-432720;Reactome: R-HSA-190873;Reactome: R-HSA-196025 "WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Lysosome Vesicle Biogenesis";"Gap junction degradation";"Formation of annular gap junctions" XP_037819734.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_037814222.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037810511.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase" XP_037818571.1 56 Reactome: R-HSA-5689603;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-4641258;Reactome: R-HSA-8939236;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-68949;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-2871837;Reactome: R-HSA-180534 "UCH proteinases";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"Degradation of DVL";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"FCERI mediated NF-kB activation";"Vpu mediated degradation of CD4" XP_037816767.1 4 Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-77075;MetaCyc: PWY-7375 "mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"Mrna capping I" XP_037817428.1 8 Reactome: R-HSA-1222556;Reactome: R-HSA-167590;Reactome: R-HSA-917977;Reactome: R-HSA-182218;Reactome: R-HSA-77387;Reactome: R-HSA-9636467;Reactome: R-HSA-9639288;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Nef Mediated CD4 Down-regulation";"Transferrin endocytosis and recycling";"Nef Mediated CD8 Down-regulation";"Insulin receptor recycling";"Blockage of phagosome acidification";"Amino acids regulate mTORC1";"Ion channel transport" XP_037818494.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_037815695.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_037828526.1 4 KEGG: 00561+2.7.1.30;KEGG: 00040+2.7.1.17;Reactome: R-HSA-5661270;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Pentose and glucuronate interconversions";"Formation of xylulose-5-phosphate";"Glycerol degradation I" XP_037815883.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037809967.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037813495.1 2 MetaCyc: PWY-6558;Reactome: R-HSA-2022928 "Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis" XP_037807871.1 9 MetaCyc: PWY-6118;MetaCyc: PWY-7385;MetaCyc: PWY-7902;MetaCyc: PWY-5667;KEGG: 00564+1.1.1.94;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.8 "Glycerol-3-phosphate shuttle";"1,3-propanediol biosynthesis (engineered)";"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism" XP_037822489.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037822762.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037808031.1 10 KEGG: 00010+2.7.2.3;MetaCyc: PWY-6901;Reactome: R-HSA-70171;MetaCyc: PWY-8004;Reactome: R-HSA-70263;KEGG: 00710+2.7.2.3;MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-6886;MetaCyc: PWY-5484 "Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycolysis";"Entner-Doudoroff pathway I";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)" XP_037814268.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037806320.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_037825923.1 10 Reactome: R-HSA-72706;Reactome: R-HSA-72731;Reactome: R-HSA-72649;Reactome: R-HSA-381042;Reactome: R-HSA-72702;Reactome: R-HSA-9648895;Reactome: R-HSA-382556;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-9633012 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Recycling of eIF2:GDP";"Translation initiation complex formation";"PERK regulates gene expression";"Ribosomal scanning and start codon recognition";"Response of EIF2AK1 (HRI) to heme deficiency";"ABC-family proteins mediated transport";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_037822328.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_037827130.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037812314.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_037808615.1 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" XP_037826497.1 13 Reactome: R-HSA-74259;KEGG: 00240+3.6.1.9;KEGG: 00500+3.6.1.9;KEGG: 00770+3.6.1.9;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7821;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.66;MetaCyc: PWY-7184;KEGG: 00740+3.6.1.9;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7206;MetaCyc: PWY-7187 "Purine catabolism";"Pyrimidine metabolism";"Starch and sucrose metabolism";"Pantothenate and CoA biosynthesis";"Purine metabolism";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Riboflavin metabolism";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II" XP_037819933.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_037817734.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037814317.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_037810637.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004 "Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Clathrin-mediated endocytosis";"Negative regulation of MET activity" XP_037819543.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_037807747.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-264870;Reactome: R-HSA-6794361 "Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins";"Neurexins and neuroligins" XP_037824911.1 8 MetaCyc: PWY-241;MetaCyc: PWY-7117;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-6142 "C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_037816216.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_037815460.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037828306.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394 "Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER" XP_037827935.1 6 Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters" XP_037810812.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_037805889.1 29 Reactome: R-HSA-427413;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-6781823;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-76042;Reactome: R-HSA-73772;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-113418;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-167152;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-72086 "NoRC negatively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the Early Elongation Complex";"Dual incision in TC-NER";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping" XP_037822399.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037806393.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037823893.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308 "Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening" XP_037811026.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037815328.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294 "SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors" XP_037808218.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_037820326.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037808907.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_037815749.1 2 Reactome: R-HSA-204174;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid" XP_037828804.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037817263.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037813653.1 4 MetaCyc: PWY-6482;Reactome: R-HSA-5358493;Reactome: R-HSA-8849175;MetaCyc: PWY-7546 "Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Threonine catabolism";"Diphthamide biosynthesis II (eukaryotes)" XP_037827625.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037815896.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_037825062.1 13 MetaCyc: PWY-7198;KEGG: 00230+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7220;MetaCyc: PWY-7210;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7226;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7222;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7227 "Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis" XP_037822905.1 18 KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1482839;MetaCyc: PWY-7783;MetaCyc: PWY-7416;Reactome: R-HSA-1483166;MetaCyc: PWY-7409;Reactome: R-HSA-1482925;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-8051;Reactome: R-HSA-1482801;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4 "alpha-Linolenic acid metabolism";"Acyl chain remodelling of PI";"Acyl chain remodelling of PE";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Synthesis of PA";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PG";"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Glycerophospholipid metabolism" XP_037815292.1 15 Reactome: R-HSA-9665251;Reactome: R-HSA-9652282;Reactome: R-HSA-9634285;Reactome: R-HSA-9665245;Reactome: R-HSA-9665249;Reactome: R-HSA-1227986;Reactome: R-HSA-9665244;Reactome: R-HSA-1236382;Reactome: R-HSA-9665250;Reactome: R-HSA-5637810;Reactome: R-HSA-9664565;Reactome: R-HSA-9665247;Reactome: R-HSA-9665246;Reactome: R-HSA-8863795;Reactome: R-HSA-9665233 "Resistance of ERBB2 KD mutants to lapatinib";"Drug-mediated inhibition of ERBB2 signaling";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to afatinib";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to sapitinib";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Resistance of ERBB2 KD mutants to AEE788";"Constitutive Signaling by EGFRvIII";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to osimertinib";"Resistance of ERBB2 KD mutants to neratinib";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to trastuzumab" XP_037805624.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154 "Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase" XP_037806775.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis" XP_037826383.1 3 KEGG: 00534+5.1.3.17;Reactome: R-HSA-2022928;MetaCyc: PWY-6558 "Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)" XP_037810503.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-141444 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_037820719.1 7 KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis" XP_037819720.1 14 MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-8055;MetaCyc: PWY-8053;KEGG: 00565+3.1.3.4;Reactome: R-HSA-1483191;Reactome: R-HSA-4419969;MetaCyc: PWY-8052;Reactome: R-HSA-75109;Reactome: R-HSA-1483213;MetaCyc: PWY-8051;KEGG: 00561+3.1.3.4;KEGG: 00564+3.1.3.4;KEGG: 00600+3.1.3.4 "Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Ether lipid metabolism";"Synthesis of PC";"Depolymerisation of the Nuclear Lamina";"2-arachidonoylglycerol biosynthesis";"Triglyceride biosynthesis";"Synthesis of PE";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Sphingolipid metabolism" XP_037826454.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_037813179.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_037815938.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_037806472.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway" XP_037809076.1 2 Reactome: R-HSA-380095;Reactome: R-HSA-416476 "Tachykinin receptors bind tachykinins";"G alpha (q) signalling events" XP_037822488.1 3 MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism" XP_037810334.1 14 Reactome: R-HSA-71403;MetaCyc: PWY-561;MetaCyc: PWY-7279;MetaCyc: PWY-3781;KEGG: 00190+1.3.5.1;KEGG: 00650+1.3.5.1;MetaCyc: PWY-6969;KEGG: 00020+1.3.5.1;KEGG: 00720+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-4302;MetaCyc: PWY-7254;MetaCyc: PWY-6728;MetaCyc: PWY-5690 "Citric acid cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"Butanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Respiratory electron transport";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"TCA cycle II (plants and fungi)" XP_037823622.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway" XP_037811296.1 2 KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10 "Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis" XP_037814311.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_037824770.1 2 Reactome: R-HSA-444821;Reactome: R-HSA-418555 "Relaxin receptors";"G alpha (s) signalling events" XP_037811462.1 5 Reactome: R-HSA-189451;KEGG: 00860+4.1.1.37;MetaCyc: PWY-5531;MetaCyc: PWY-7159;MetaCyc: PWY-7766 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme b biosynthesis IV (Gram-positive bacteria)" XP_037813708.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_037814892.1 18 KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482801;MetaCyc: PWY-7417;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-7409;Reactome: R-HSA-1483166;Reactome: R-HSA-1482839;MetaCyc: PWY-7783;Reactome: R-HSA-1482922;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416 "Linoleic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Synthesis of PA";"Acyl chain remodelling of PE";"Plasmalogen degradation";"Acyl chain remodelling of PI";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)" XP_037818087.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_037820586.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_037812586.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_037822822.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037809953.1 8 Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-113507;Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-68616 "Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication" XP_037811755.1 13 Reactome: R-HSA-2024101;MetaCyc: PWY-7883;Reactome: R-HSA-2022857;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52 "CS/DS degradation";"Anhydromuropeptides recycling II";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation" XP_037817234.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_037805413.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037824967.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_037807121.1 2 Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_037809540.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_037822659.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" YP_001425546.1 7 Reactome: R-HSA-611105;MetaCyc: PWY-4302;KEGG: 00190+7.1.1.2;MetaCyc: PWY-6692;Reactome: R-HSA-6799198;MetaCyc: PWY-5083;MetaCyc: PWY-3781 "Respiratory electron transport";"Aerobic respiration III (alternative oxidase pathway)";"Oxidative phosphorylation";"Fe(II) oxidation";"Complex I biogenesis";"NAD/NADH phosphorylation and dephosphorylation";"Aerobic respiration I (cytochrome c)" XP_037812868.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_037814589.1 5 Reactome: R-HSA-110357;Reactome: R-HSA-5221030;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-3108214 "Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins" XP_037819495.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_037815311.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037825106.1 5 MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-5083 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation" XP_037810013.1 56 Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-2871837;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-174154;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-5689603;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-68949;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-5610783 "Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"FCERI mediated NF-kB activation";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"APC/C:Cdc20 mediated degradation of Securin";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"UCH proteinases";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Orc1 removal from chromatin";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI2 by the proteasome" XP_037823993.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_037820483.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_037813615.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_037814162.1 11 Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-68962;Reactome: R-HSA-5651801;Reactome: R-HSA-68952;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-174430;Reactome: R-HSA-110314;Reactome: R-HSA-5696397 "HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of the pre-replicative complex";"PCNA-Dependent Long Patch Base Excision Repair";"DNA replication initiation";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Telomere C-strand synthesis initiation";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER" XP_037809634.1 22 Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-68877;Reactome: R-HSA-5675221;Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-4641262;Reactome: R-HSA-141444;Reactome: R-HSA-195253;Reactome: R-HSA-5467337;Reactome: R-HSA-2500257;Reactome: R-HSA-5358751;Reactome: R-HSA-432142;Reactome: R-HSA-6811558;Reactome: R-HSA-9648025;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-5673000;Reactome: R-HSA-5467340;Reactome: R-HSA-196299 "S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Negative regulation of MAPK pathway";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding";"Resolution of Sister Chromatid Cohesion";"S45 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"EML4 and NUDC in mitotic spindle formation";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"RAF activation";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade" XP_037817268.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037805726.1 4 KEGG: 00230+6.3.5.2;MetaCyc: PWY-7221;Reactome: R-HSA-73817;KEGG: 00983+6.3.5.2 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes" XP_037808346.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037806153.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_037827652.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_037810501.1 4 Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin" XP_037814590.1 5 Reactome: R-HSA-3108214;Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-5221030;Reactome: R-HSA-110357 "SUMOylation of DNA damage response and repair proteins";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1" XP_037821903.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_037811826.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_037822753.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" XP_037824178.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037805489.1 3 Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646 "Defective ACY1 causes encephalopathy";"Arginine biosynthesis";"Aflatoxin activation and detoxification" XP_037824416.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037820778.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037811686.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037806806.1 7 Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-177929;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606;Reactome: R-HSA-1442490;Reactome: R-HSA-2894862 "Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_037811521.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764 "Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination" XP_037805626.1 4 Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724 "RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription" XP_037817948.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037827160.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_037826234.1 17 Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-6790901;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72764 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"rRNA modification in the nucleus and cytosol";"Peptide chain elongation";"Viral mRNA Translation";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination" XP_037820298.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037814407.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_037808555.1 7 Reactome: R-HSA-2122948;MetaCyc: PWY-7511;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606 "Activated NOTCH1 Transmits Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_037825601.1 20 Reactome: R-HSA-69091;Reactome: R-HSA-176187;Reactome: R-HSA-6782135;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-110312;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-110320;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210 "Polymerase switching";"Activation of ATR in response to replication stress";"Dual incision in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Translesion synthesis by REV1";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_037808605.1 3 Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_037814453.1 27 Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-168271 "Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"tRNA processing in the nucleus";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus" XP_037807357.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_037814408.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_037805320.1 1 Reactome: R-HSA-480985 "Synthesis of dolichyl-phosphate-glucose" XP_037814215.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037805496.1 4 KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922;MetaCyc: PWY-5737;Reactome: R-HSA-70688 "Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism" XP_037806785.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_037805462.1 27 Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-191859 "NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"tRNA processing in the nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"snRNP Assembly" XP_037828347.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037813700.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_037808685.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_037807931.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_037818363.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037820741.1 16 Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-176412;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-176409;Reactome: R-HSA-69017 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6" XP_037818861.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037805894.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037809326.1 11 Reactome: R-HSA-3299685;Reactome: R-HSA-1268020;Reactome: R-HSA-2151201;Reactome: R-HSA-111463;Reactome: R-HSA-5628897;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-111457;Reactome: R-HSA-9627069;Reactome: R-HSA-611105;Reactome: R-HSA-111464 "Detoxification of Reactive Oxygen Species";"Mitochondrial protein import";"Transcriptional activation of mitochondrial biogenesis";"SMAC (DIABLO) binds to IAPs";"TP53 Regulates Metabolic Genes";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity";"Respiratory electron transport";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes" XP_037807129.1 4 Reactome: R-HSA-71240;Reactome: R-HSA-5660862;Reactome: R-HSA-210991;Reactome: R-HSA-352230 "Tryptophan catabolism";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Basigin interactions";"Amino acid transport across the plasma membrane" XP_037818065.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037806546.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037817807.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037816604.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037827054.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_037821314.1 3 Reactome: R-HSA-400206;Reactome: R-HSA-427413;Reactome: R-HSA-8936459 "Regulation of lipid metabolism by PPARalpha";"NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_037818135.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_037826210.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037825837.1 56 Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-1169091;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-75815;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-69017;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664 "Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Activation of NF-kappaB in B cells";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation" XP_037809918.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_037821933.1 13 KEGG: 00480+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7222;KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-6545;MetaCyc: PWY-7198;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7184;Reactome: R-HSA-499943 "Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates" XP_037815575.1 5 Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-3249367;Reactome: R-HSA-1834941;Reactome: R-HSA-3134975 "IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"STAT6-mediated induction of chemokines";"STING mediated induction of host immune responses";"Regulation of innate immune responses to cytosolic DNA" XP_037806156.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037806248.1 8 KEGG: 04926+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1 "Relaxin signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection" XP_037819978.1 6 Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-69473 "HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint" XP_037816945.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037824817.1 5 Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Late endosomal microautophagy";"HCMV Late Events" XP_037820384.1 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" XP_037815043.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_037817467.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_037815107.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037805447.1 2 Reactome: R-HSA-177128;Reactome: R-HSA-177135 "Conjugation of salicylate with glycine";"Conjugation of benzoate with glycine" XP_037821743.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037813499.1 1 Reactome: R-HSA-419771 "Opsins" XP_037819430.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_037822924.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037814403.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_037808586.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037819733.1 4 Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664 "Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Neddylation" XP_037814401.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_037815245.1 13 MetaCyc: PWY-8086;KEGG: 00620+4.2.1.2;MetaCyc: PWY-6728;MetaCyc: PWY-5913;KEGG: 00720+4.2.1.2;MetaCyc: PWY-5690;MetaCyc: PWY-561;MetaCyc: PWY-5392;Reactome: R-HSA-71403;MetaCyc: PWY-7384;MetaCyc: PWY-7254;KEGG: 00020+4.2.1.2;MetaCyc: PWY-6969 "(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" XP_037825398.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037818364.1 7 MetaCyc: PWY-6277;MetaCyc: PWY-6121;KEGG: 00230+2.4.2.14;MetaCyc: PWY-7282;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6122;Reactome: R-HSA-73817 "Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis" XP_037809704.1 6 KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817 "Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_037822325.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_037825556.1 5 MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism" XP_037816237.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037811820.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037821875.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037821113.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism" XP_037822495.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037813966.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037824732.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_037812368.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037814914.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037817725.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_037825762.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_037815329.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294 "SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors" XP_037811687.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037806768.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway" XP_037824048.1 8 KEGG: 00051+4.2.1.47;MetaCyc: PWY-66;MetaCyc: PWY-5738;MetaCyc: PWY-5740;MetaCyc: PWY-7573;MetaCyc: PWY-5739;Reactome: R-HSA-6787639;KEGG: 00520+4.2.1.47 "Fructose and mannose metabolism";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-6-deoxy-D-talose biosynthesis";"GDP-L-colitose biosynthesis";"GDP-mycosamine biosynthesis";"GDP-D-perosamine biosynthesis";"GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_037814907.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037805849.1 16 Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-141430;Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-8853884;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-176409;Reactome: R-HSA-69017 "Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"Transcriptional Regulation by VENTX";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6" XP_037816162.1 14 MetaCyc: PWY-5667;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15;Reactome: R-HSA-2426168;KEGG: 00564+2.3.1.15;Reactome: R-HSA-75109;MetaCyc: PWY-7411;MetaCyc: PWY-8053;MetaCyc: PWY-7587;MetaCyc: PWY-8055;Reactome: R-HSA-9018519;MetaCyc: PWY-6453;Reactome: R-HSA-8931987;Reactome: R-HSA-1483166 "CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Activation of gene expression by SREBF (SREBP)";"Glycerophospholipid metabolism";"Triglyceride biosynthesis";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Estrogen-dependent gene expression";"Stigma estolide biosynthesis";"RUNX1 regulates estrogen receptor mediated transcription";"Synthesis of PA" XP_037815099.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037818123.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037817850.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_037806458.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" XP_037821993.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037828284.1 2 MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism" XP_037827398.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_037818705.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_037816855.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037806073.1 9 MetaCyc: PWY-6703;MetaCyc: PWY-5664;MetaCyc: PWY-7852;MetaCyc: PWY-7442;MetaCyc: PWY-5663;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6983;MetaCyc: PWY-6147;Reactome: R-HSA-1474151 "Preq0 biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Folate biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_037808557.1 7 Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;MetaCyc: PWY-7511 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Protein ubiquitination" XP_037813222.1 10 Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-451308;Reactome: R-HSA-399719;Reactome: R-HSA-447038;Reactome: R-HSA-9609736 "Synaptic adhesion-like molecules";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Activation of Ca-permeable Kainate Receptor";"Trafficking of AMPA receptors";"NrCAM interactions";"Assembly and cell surface presentation of NMDA receptors" XP_037809228.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-1799339 "Translation initiation complex formation";"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane" XP_037822184.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037811685.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037815348.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_037814853.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-1358803;Reactome: R-HSA-983168 "Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037823777.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_037815565.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037827636.1 8 KEGG: 00620+1.1.1.27;KEGG: 00640+1.1.1.27;MetaCyc: PWY-8086;MetaCyc: PWY-5481;MetaCyc: PWY-6901;KEGG: 00270+1.1.1.27;KEGG: 00010+1.1.1.27;Reactome: R-HSA-70268 "Pyruvate metabolism";"Propanoate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate fermentation to (S)-lactate";"Superpathway of glucose and xylose degradation";"Cysteine and methionine metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism" XP_037815878.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037822398.1 24 Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497 "Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Gap junction assembly";"HCMV Early Events";"Cilium Assembly";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Aggrephagy";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_037828299.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037816893.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport" XP_037825175.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_037807041.1 33 Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-5663220;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-191859;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-2467813;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-68877;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-9648025;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377 "SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"RHO GTPases Activate Formins";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"Separation of Sister Chromatids";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"Mitotic Prometaphase";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"EML4 and NUDC in mitotic spindle formation";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"SUMOylation of SUMOylation proteins" XP_037817896.1 1 Reactome: R-HSA-8964572 "Lipid particle organization" XP_037819626.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation" XP_037813895.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_037822738.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037815288.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_037821336.1 10 Reactome: R-HSA-2206292;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23 "MPS VII - Sly syndrome";"HS-GAG degradation";"Galactose metabolism";"Hyaluronan uptake and degradation";"Other glycan degradation";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series" XP_037816248.1 5 KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-8013;MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16 "Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III";"CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism" XP_037814829.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_037812287.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037817353.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037825620.1 17 Reactome: R-HSA-69183;Reactome: R-HSA-6782135;Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-69091;Reactome: R-HSA-5651801;Reactome: R-HSA-174414;Reactome: R-HSA-5358565;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-5358606;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-174417;Reactome: R-HSA-5685942;Reactome: R-HSA-174411 "Processive synthesis on the lagging strand";"Dual incision in TC-NER";"Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"Polymerase switching";"PCNA-Dependent Long Patch Base Excision Repair";"Processive synthesis on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Telomere C-strand (Lagging Strand) Synthesis";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere" XP_037807879.1 9 Reactome: R-HSA-1483166;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7411;MetaCyc: PWY-6118;MetaCyc: PWY-7385;MetaCyc: PWY-5667;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7902 "Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Glycerol-3-phosphate shuttle";"1,3-propanediol biosynthesis (engineered)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis" XP_037811695.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I" XP_037817568.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037823891.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037805314.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037813656.1 3 MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805 "Glyphosate degradation III";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation" XP_037817999.1 1 Reactome: R-HSA-191273 "Cholesterol biosynthesis" XP_037824052.1 10 MetaCyc: PWY-6142;KEGG: 00562+5.3.1.1;KEGG: 00051+5.3.1.1;Reactome: R-HSA-70171;Reactome: R-HSA-70263;KEGG: 00710+5.3.1.1;KEGG: 00010+5.3.1.1;MetaCyc: PWY-7003;MetaCyc: PWY-5484;MetaCyc: PWY-1042 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Inositol phosphate metabolism";"Fructose and mannose metabolism";"Glycolysis";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)" XP_037823169.1 6 MetaCyc: PWY-5789;MetaCyc: PWY-6722;MetaCyc: PWY-5743;MetaCyc: PWY-4381;Reactome: R-HSA-196780;MetaCyc: PWY-5744 "3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Biotin transport and metabolism";"Glyoxylate assimilation" XP_037819811.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_037822335.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_037807286.1 3 KEGG: 00240+3.6.1.17;KEGG: 00230+3.6.1.17;Reactome: R-HSA-3299685 "Pyrimidine metabolism";"Purine metabolism";"Detoxification of Reactive Oxygen Species" XP_037825715.1 56 Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-75815;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664 "Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation" XP_037810714.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_037825092.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_037814962.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-2408508 "Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_037805783.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706 "Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037822741.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037817919.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_037808587.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037811854.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037809632.1 22 Reactome: R-HSA-6811558;Reactome: R-HSA-9648025;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-5673000;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-141444;Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-2500257;Reactome: R-HSA-5358751;Reactome: R-HSA-432142;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-4641262;Reactome: R-HSA-5358749;Reactome: R-HSA-5675221;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-389513;Reactome: R-HSA-5339716 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"EML4 and NUDC in mitotic spindle formation";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"RAF activation";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"Resolution of Sister Chromatid Cohesion";"S45 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S37 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Misspliced GSK3beta mutants stabilize beta-catenin" XP_037813276.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_037806209.1 6 Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-69052 "Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state" XP_037805634.1 5 KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2 "Lysine degradation";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism" XP_037818975.1 2 Reactome: R-HSA-190873;Reactome: R-HSA-399719 "Gap junction degradation";"Trafficking of AMPA receptors" XP_037824764.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_037815782.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037822456.1 19 Reactome: R-HSA-8957275;Reactome: R-HSA-3000471;Reactome: R-HSA-8964046;Reactome: R-HSA-8963901;Reactome: R-HSA-5686938;Reactome: R-HSA-8964041;Reactome: R-HSA-432142;Reactome: R-HSA-3000497;Reactome: R-HSA-8964038;Reactome: R-HSA-3000484;Reactome: R-HSA-8866423;Reactome: R-HSA-8964026;Reactome: R-HSA-202733;Reactome: R-HSA-8963888;Reactome: R-HSA-975634;Reactome: R-HSA-381426;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-3000480 "Post-translational protein phosphorylation";"Scavenging by Class B Receptors";"VLDL clearance";"Chylomicron remodeling";"Regulation of TLR by endogenous ligand";"LDL remodeling";"Platelet sensitization by LDL";"Scavenging by Class H Receptors";"LDL clearance";"Scavenging by Class F Receptors";"VLDL assembly";"Chylomicron clearance";"Cell surface interactions at the vascular wall";"Chylomicron assembly";"Retinoid metabolism and transport";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class A Receptors" XP_037821924.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-111447 "TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria" XP_037826251.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_037817579.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037818702.1 11 KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-5610787 "Purine metabolism";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"PKA activation";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state" XP_037817372.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037808607.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers" XP_037825667.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_037809549.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_037816491.1 31 MetaCyc: PWY-5971;MetaCyc: PWY-6799;MetaCyc: PWY-7388;MetaCyc: PWY-5966-1;MetaCyc: PWY-8047;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-75105;MetaCyc: PWYG-321;MetaCyc: PWY-5367;MetaCyc: PWY-7723;Reactome: R-HSA-199220;MetaCyc: PWY-5147;MetaCyc: PWY-5142;MetaCyc: PWY-6519;MetaCyc: PWY-4381;MetaCyc: PWY-5366;MetaCyc: PWY-7664;MetaCyc: PWY-8012;MetaCyc: PWY-7663;MetaCyc: PWY-7858;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5973;MetaCyc: PWY-6113;Reactome: R-HSA-9029558;Reactome: R-HSA-2426168;MetaCyc: PWY-5989;MetaCyc: PWY-6282;MetaCyc: PWY-8049;MetaCyc: PWY-5994;MetaCyc: PWY-7746;Reactome: R-HSA-163765 "Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Bryostatin biosynthesis";"Biotin metabolism";"Fatty acyl-CoA biosynthesis";"";"Petroselinate biosynthesis";"Bacterial bioluminescence";"Vitamin B5 (pantothenate) metabolism";"Oleate biosynthesis I (plants)";"Acyl-[acyl-carrier protein] thioesterase pathway";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitoleate biosynthesis II (plants and bacteria)";"Oleate biosynthesis IV (anaerobic)";"Mupirocin biosynthesis";"Gondoate biosynthesis (anaerobic)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis";"Cis-vaccenate biosynthesis";"Superpathway of mycolate biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)";"Stearate biosynthesis II (bacteria and plants)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Pederin biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Mycobacterial sulfolipid biosynthesis";"ChREBP activates metabolic gene expression" XP_037820617.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037809450.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037814880.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037828809.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037825474.1 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" XP_037812835.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_037817308.1 9 MetaCyc: PWY-6367;MetaCyc: PWY-6351;Reactome: R-HSA-112043;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;Reactome: R-HSA-416476;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11 "D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system" XP_037808460.1 6 Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "Triglyceride catabolism";"T cell receptor signaling pathway";"Circadian Clock";"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_037806991.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_037816502.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_037823547.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037807730.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037811721.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_037817732.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037819961.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037807947.1 14 Reactome: R-HSA-1912408;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-203927;Reactome: R-HSA-426496;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569 "Pre-NOTCH Transcription and Translation";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"MicroRNA (miRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_037827528.1 5 Reactome: R-HSA-5083630;Reactome: R-HSA-350054;Reactome: R-HSA-1912399;Reactome: R-HSA-1912420;Reactome: R-HSA-1912408 "Defective LFNG causes SCDO3";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Transcription and Translation" XP_037818514.1 8 MetaCyc: PWY-7199;KEGG: 00240+3.5.4.5;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7193;MetaCyc: PWY-6556;Reactome: R-HSA-73614;MetaCyc: PWY-7181;Reactome: R-HSA-6798695 "Pyrimidine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine ribonucleosides salvage II";"Pyrimidine salvage";"Pyrimidine deoxyribonucleosides degradation";"Neutrophil degranulation" XP_037806693.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_037821337.1 10 Reactome: R-HSA-2024096;Reactome: R-HSA-2206292;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23 "HS-GAG degradation";"MPS VII - Sly syndrome";"Other glycan degradation";"Hyaluronan uptake and degradation";"Galactose metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation" XP_037806461.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037827305.1 14 Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167243 "Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery" XP_037810966.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_037811754.1 13 KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;Reactome: R-HSA-2022857;KEGG: 00604+3.2.1.52 "Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"CS/DS degradation";"Anhydromuropeptides recycling II";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - ganglio series" XP_037817974.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037813609.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_037823061.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037818798.1 29 KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804760;Reactome: R-HSA-6803204;Reactome: R-HSA-69541;Reactome: R-HSA-5693554;Reactome: R-HSA-349425;Reactome: R-HSA-5685938;Reactome: R-HSA-5693571;Reactome: R-HSA-2559586;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-6796648;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-6803207;Reactome: R-HSA-3371453;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693548;KEGG: 04926+2.7.11.1;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-69473;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693568;Reactome: R-HSA-5693565 "Human cytomegalovirus infection";"Regulation of TP53 Activity through Methylation";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Stabilization of p53";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Autodegradation of the E3 ubiquitin ligase COP1";"HDR through Single Strand Annealing (SSA)";"Nonhomologous End-Joining (NHEJ)";"DNA Damage/Telomere Stress Induced Senescence";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"TP53 Regulates Transcription of DNA Repair Genes";"Thermogenesis";"Regulation of TP53 Degradation";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of HSF1-mediated heat shock response";"mTOR signaling pathway";"Sensing of DNA Double Strand Breaks";"Relaxin signaling pathway";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"G2/M DNA damage checkpoint";"Human papillomavirus infection";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_037820010.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037821067.1 6 KEGG: 00564+1.1.5.3;MetaCyc: PWY-6952;Reactome: R-HSA-163560;MetaCyc: PWY-6118;MetaCyc: PWY-4261;Reactome: R-HSA-1483166 "Glycerophospholipid metabolism";"Glycerophosphodiester degradation";"Triglyceride catabolism";"Glycerol-3-phosphate shuttle";"Glycerol degradation I";"Synthesis of PA" XP_037806704.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037809504.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_037818842.1 7 KEGG: 00480+6.3.2.2;MetaCyc: PWY-6840;KEGG: 00270+6.3.2.2;MetaCyc: PWY-8043;Reactome: R-HSA-174403;MetaCyc: PWY-7255;Reactome: R-HSA-5578999 "Glutathione metabolism";"Homoglutathione biosynthesis";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Ergothioneine biosynthesis I (bacteria)";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)" XP_037821655.1 8 Reactome: R-HSA-111464;Reactome: R-HSA-111458;Reactome: R-HSA-6803207;Reactome: R-HSA-111459;Reactome: R-HSA-8953750;Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-6798695 "SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional Regulation by E2F6";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"Neutrophil degranulation" XP_037824615.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_037817313.1 4 MetaCyc: PWY-7221;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541 "Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Abacavir metabolism" XP_037809533.1 24 Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-9648025;Reactome: R-HSA-437239;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-190861 "RHO GTPases Activate Formins";"Aggrephagy";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Recycling pathway of L1";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"HCMV Early Events";"Gap junction assembly" XP_037820907.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037807117.1 56 Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-4641257;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-69017;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-174178;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5689603;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-8939236;Reactome: R-HSA-350562;Reactome: R-HSA-1236978 "Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Degradation of AXIN";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"UCH proteinases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)" XP_037807481.1 5 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-7822 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)" XP_037814553.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037812398.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037812172.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_037812071.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_037814854.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_037813677.1 6 Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-450513 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_037819479.1 3 Reactome: R-HSA-189451;MetaCyc: PWY-7159;KEGG: 00860+1.3.3.4 "Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism" XP_037810753.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037825298.1 3 Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161 "Metabolism of folate and pterines";"Folate biosynthesis";"Folate polyglutamylation" YP_001425544.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_037813719.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037821020.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_037812987.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037814697.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037814926.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_037806758.1 7 KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway" XP_037805720.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_037815336.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_037822240.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_037810314.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"Aggrephagy";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_037810640.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8875360 "Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell" XP_037823903.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_037814815.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037814008.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037807560.1 4 Reactome: R-HSA-3000178;Reactome: R-HSA-216083;Reactome: R-HSA-2129379;Reactome: R-HSA-3000170 "ECM proteoglycans";"Integrin cell surface interactions";"Molecules associated with elastic fibres";"Syndecan interactions" XP_037821918.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-75035 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex" XP_037817679.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216 "Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen chain trimerization" XP_037820685.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72764 "Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination" XP_037817718.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_037815577.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037807182.1 2 Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_037812085.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037809494.1 20 KEGG: 00410+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7574;MetaCyc: PWY-7854;Reactome: R-HSA-9033241;MetaCyc: PWY-7606;MetaCyc: PWY-7291;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-5136;MetaCyc: PWY-6837;MetaCyc: PWY-735;MetaCyc: PWY-7337;KEGG: 00592+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-6920;MetaCyc: PWY-7726;MetaCyc: PWY-7858;MetaCyc: PWY-7340 "beta-Alanine metabolism";"Methyl ketone biosynthesis (engineered)";"Propanoyl-coa degradation II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Peroxisomal protein import";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Jasmonic acid biosynthesis";"10-cis-heptadecenoyl-CoA degradation (yeast)";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"Fatty acid beta-oxidation VII (yeast peroxisome)";"6-gingerol analog biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(5Z)-dodecenoate biosynthesis II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)" XP_037810646.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_037815648.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_037810361.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037823781.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037810500.1 4 Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin" XP_037819723.1 14 MetaCyc: PWY-8051;Reactome: R-HSA-1483213;KEGG: 00561+3.1.3.4;KEGG: 00564+3.1.3.4;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052;Reactome: R-HSA-75109;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053;Reactome: R-HSA-4419969;Reactome: R-HSA-1483191;MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-6453 "Anandamide biosynthesis I";"Synthesis of PE";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Triglyceride biosynthesis";"Ether lipid metabolism";"Anandamide biosynthesis II";"Depolymerisation of the Nuclear Lamina";"Synthesis of PC";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis" XP_037822972.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_037827666.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037808396.1 3 Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067 "Glycogen synthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)" XP_037822279.1 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" XP_037819928.1 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" XP_037814259.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037806990.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2 "VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway" XP_037806105.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037822694.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037823193.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037810632.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037826476.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037806259.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037816876.1 5 Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920 "Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability" XP_037813897.1 13 Reactome: R-HSA-2206308;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-1660662;Reactome: R-HSA-4341670;Reactome: R-HSA-4085001;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-6798695;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2022857 "MPS IV - Morquio syndrome B";"Galactose metabolism";"Other glycan degradation";"Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis";"Sialic acid metabolism";"HS-GAG degradation";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Keratan sulfate degradation" XP_037822795.1 3 Reactome: R-HSA-8868766;Reactome: R-HSA-6784531;Reactome: R-HSA-6785470 "rRNA processing in the mitochondrion";"tRNA processing in the nucleus";"tRNA processing in the mitochondrion" XP_037812382.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037810343.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037821601.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037810863.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037817189.1 42 Reactome: R-HSA-73772;Reactome: R-HSA-110328;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-9609690;Reactome: R-HSA-8939236;Reactome: R-HSA-212300;Reactome: R-HSA-4551638;Reactome: R-HSA-201722;Reactome: R-HSA-427413;Reactome: R-HSA-9018519;Reactome: R-HSA-110331;Reactome: R-HSA-1221632;Reactome: R-HSA-606279;Reactome: R-HSA-73728;Reactome: R-HSA-5250924;Reactome: R-HSA-69473;Reactome: R-HSA-5625886;Reactome: R-HSA-5693565;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-2559582;Reactome: R-HSA-2299718;Reactome: R-HSA-3214842;Reactome: R-HSA-2559586;Reactome: R-HSA-8936459;Reactome: R-HSA-2559580;Reactome: R-HSA-110329;Reactome: R-HSA-5334118;Reactome: R-HSA-171306;Reactome: R-HSA-9610379;Reactome: R-HSA-5617472;Reactome: R-HSA-427359;Reactome: R-HSA-9616222;Reactome: R-HSA-3214847;Reactome: R-HSA-912446;Reactome: R-HSA-3214858;Reactome: R-HSA-5578749;Reactome: R-HSA-977225;Reactome: R-HSA-1912408;Reactome: R-HSA-3214841;Reactome: R-HSA-110330 "RNA Polymerase I Promoter Escape";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"HCMV Early Events";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins";"Formation of the beta-catenin:TCF transactivating complex";"NoRC negatively regulates rRNA expression";"Estrogen-dependent gene expression";"Cleavage of the damaged purine";"Meiotic synapsis";"Deposition of new CENPA-containing nucleosomes at the centromere";"RNA Polymerase I Promoter Opening";"B-WICH complex positively regulates rRNA expression";"G2/M DNA damage checkpoint";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Senescence-Associated Secretory Phenotype (SASP)";"Condensation of Prophase Chromosomes";"HDMs demethylate histones";"DNA Damage/Telomere Stress Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Oxidative Stress Induced Senescence";"Cleavage of the damaged pyrimidine";"DNA methylation";"Packaging Of Telomere Ends";"HCMV Late Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SIRT1 negatively regulates rRNA expression";"Transcriptional regulation of granulopoiesis";"HATs acetylate histones";"Meiotic recombination";"RMTs methylate histone arginines";"Transcriptional regulation by small RNAs";"Amyloid fiber formation";"Pre-NOTCH Transcription and Translation";"PKMTs methylate histone lysines";"Recognition and association of DNA glycosylase with site containing an affected purine" XP_037813797.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037821524.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259 "Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes" XP_037819395.1 16 Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-983168 "Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037825606.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_037817468.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037824679.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_037821445.1 19 Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-9617324;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-111932;Reactome: R-HSA-5673000;Reactome: R-HSA-5576892;Reactome: R-HSA-6802946;Reactome: R-HSA-438066;Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001 "Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Interferon gamma signaling";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB";"RAF activation";"Phase 0 - rapid depolarisation";"Signaling by moderate kinase activity BRAF mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"RAF/MAP kinase cascade" XP_037824914.1 8 KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway" XP_037819247.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037814905.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037806941.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_037815444.1 7 MetaCyc: PWY-6614;KEGG: 00670+1.5.1.3;Reactome: R-HSA-69205;Reactome: R-HSA-1474151;KEGG: 00790+1.5.1.3;Reactome: R-HSA-196757;MetaCyc: PWY-3841 "Tetrahydrofolate biosynthesis";"One carbon pool by folate";"G1/S-Specific Transcription";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis";"Metabolism of folate and pterines";"Folate transformations II (plants)" XP_037826532.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_037820258.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037822059.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_037827845.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_037828626.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_037820456.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_037818459.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase" XP_037812383.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037815915.1 11 Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-432040 "Glucagon signaling in metabolic regulation";"PKA activation";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Purine metabolism";"Hedgehog 'off' state";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_037823343.1 12 Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-6807878;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-381038;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942 "Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"COPI-mediated anterograde transport";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"XBP1(S) activates chaperone genes";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition" XP_037826030.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037819282.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_037816766.1 4 MetaCyc: PWY-7375;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-72086 "Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping" XP_037821408.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037812547.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_037820400.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037828281.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_037813864.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037817923.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_037812832.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_037820948.1 2 KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281 "Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_037827822.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_037809620.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037825964.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_037824520.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037814214.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037814298.1 6 MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;MetaCyc: PWY-5067;Reactome: R-HSA-189085;KEGG: 00500+3.2.1.1 "Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_037809360.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037828906.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037807448.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037823776.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_037814120.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037809622.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037819957.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450513 "Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_037827156.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037805426.1 10 MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00052+2.7.1.11 "Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Glycolysis";"Methane metabolism";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Galactose metabolism" XP_037815363.1 4 Reactome: R-HSA-6802952;Reactome: R-HSA-1632852;Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Signaling by BRAF and RAF fusions";"Macroautophagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" XP_037814906.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037826786.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_037820995.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_037826657.1 12 Reactome: R-HSA-2408550;MetaCyc: PWY-6932;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5278;Reactome: R-HSA-174362;KEGG: 00920+2.7.1.25;KEGG: 00920+2.7.7.4;KEGG: 00450+2.7.7.4;MetaCyc: PWY-6683;KEGG: 00230+2.7.1.25;MetaCyc: PWY-5340;KEGG: 00230+2.7.7.4 "Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Selenate reduction";"Monobactam biosynthesis";"Sulfite oxidation III";"Transport and synthesis of PAPS";"Sulfur metabolism";"Sulfur metabolism";"Selenocompound metabolism";"Assimilatory sulfate reduction III";"Purine metabolism";"Sulfate activation for sulfonation";"Purine metabolism" XP_037810353.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_037817340.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_037822816.1 8 Reactome: R-HSA-8948747;Reactome: R-HSA-6782135;Reactome: R-HSA-6804757;Reactome: R-HSA-5689880;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-8866652 "Regulation of PTEN localization";"Dual incision in TC-NER";"Regulation of TP53 Degradation";"Ub-specific processing proteases";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes" XP_037809705.1 6 KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817 "Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_037828894.1 12 MetaCyc: PWY-6672;KEGG: 00720+6.2.1.1;MetaCyc: PWY-7118;KEGG: 00630+6.2.1.1;MetaCyc: PWY-5132;MetaCyc: PWY-5108;KEGG: 00010+6.2.1.1;MetaCyc: PWY-5133;KEGG: 00620+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00680+6.2.1.1 "Cis-genanyl-coa degradation";"Carbon fixation pathways in prokaryotes";"Chitin degradation to ethanol";"Glyoxylate and dicarboxylate metabolism";"Lupulone and humulone biosynthesis";"L-isoleucine biosynthesis V";"Glycolysis / Gluconeogenesis";"Colupulone and cohumulone biosynthesis";"Pyruvate metabolism";"Propanoate metabolism";"Adlupulone and adhumulone biosynthesis";"Methane metabolism" XP_037806185.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037818062.1 2 Reactome: R-HSA-1912420;KEGG: 00514+2.4.1.222 "Pre-NOTCH Processing in Golgi";"Other types of O-glycan biosynthesis" XP_037828274.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_037818827.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037807563.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037806694.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_037827966.1 57 Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-75815;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-2871837;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-174154;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-1169091;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-5610783;Reactome: R-HSA-6798695;Reactome: R-HSA-4641258;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-5689603;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-8854050 "Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"FCERI mediated NF-kB activation";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"APC/C:Cdc20 mediated degradation of Securin";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Activation of NF-kappaB in B cells";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI2 by the proteasome";"Neutrophil degranulation";"Degradation of DVL";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"UCH proteinases";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis" XP_037828003.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037822791.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_037810341.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037827288.1 6 KEGG: 00230+4.1.1.21;KEGG: 00230+6.3.2.6;MetaCyc: PWY-6124;MetaCyc: PWY-7234;MetaCyc: PWY-6123;Reactome: R-HSA-73817 "Purine metabolism";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis" XP_037805242.1 5 KEGG: 00620+4.1.1.32;KEGG: 00010+4.1.1.32;KEGG: 00020+4.1.1.32;MetaCyc: PWY-7383;Reactome: R-HSA-70263 "Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis" XP_037811635.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_037806279.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037822500.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037816693.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_037806473.1 7 KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis" XP_037819614.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037820046.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_037828822.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037811191.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957 "Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_037820668.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_037817317.1 9 Reactome: R-HSA-112043;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;Reactome: R-HSA-416476;MetaCyc: PWY-7039;Reactome: R-HSA-1855204 "PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"G alpha (q) signalling events";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol" XP_037813808.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037811997.1 2 Reactome: R-HSA-416482;Reactome: R-HSA-456926 "G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)" XP_037818143.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037809521.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_037819249.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037810319.1 12 Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690 "Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events" XP_037812727.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_037811227.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037811427.1 5 Reactome: R-HSA-73614;KEGG: 00983+2.4.2.3;MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73621 "Pyrimidine salvage";"Drug metabolism - other enzymes";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism";"Pyrimidine catabolism" XP_037821444.1 19 Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-936837;Reactome: R-HSA-438066;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-5673000;Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-9617324;Reactome: R-HSA-6802952;Reactome: R-HSA-877300;Reactome: R-HSA-9609736;Reactome: R-HSA-3371571;Reactome: R-HSA-9022692;Reactome: R-HSA-399719 "RAF/MAP kinase cascade";"Long-term potentiation";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"RAF activation";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by BRAF and RAF fusions";"Interferon gamma signaling";"Assembly and cell surface presentation of NMDA receptors";"HSF1-dependent transactivation";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors" XP_037813551.1 8 MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105;MetaCyc: PWY-7922;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;KEGG: 00514+2.4.1.109 "Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"O-linked glycosylation";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Other types of O-glycan biosynthesis" XP_037807628.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_037811299.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037828105.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_037814920.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037820320.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037821224.1 4 KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051 "alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Anandamide biosynthesis I" XP_037806347.1 14 KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7035 "Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis" XP_037809709.1 6 MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism" XP_037823541.1 42 Reactome: R-HSA-606279;Reactome: R-HSA-110331;Reactome: R-HSA-1221632;Reactome: R-HSA-5693565;Reactome: R-HSA-5625886;Reactome: R-HSA-5250924;Reactome: R-HSA-69473;Reactome: R-HSA-73728;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-9609690;Reactome: R-HSA-110328;Reactome: R-HSA-73772;Reactome: R-HSA-9018519;Reactome: R-HSA-427413;Reactome: R-HSA-8939236;Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-201722;Reactome: R-HSA-912446;Reactome: R-HSA-5617472;Reactome: R-HSA-427359;Reactome: R-HSA-9616222;Reactome: R-HSA-3214847;Reactome: R-HSA-3214841;Reactome: R-HSA-1912408;Reactome: R-HSA-110330;Reactome: R-HSA-5578749;Reactome: R-HSA-977225;Reactome: R-HSA-3214858;Reactome: R-HSA-2559586;Reactome: R-HSA-2559580;Reactome: R-HSA-8936459;Reactome: R-HSA-110329;Reactome: R-HSA-2299718;Reactome: R-HSA-3214842;Reactome: R-HSA-427389;Reactome: R-HSA-2559582;Reactome: R-HSA-3214815;Reactome: R-HSA-9610379;Reactome: R-HSA-171306;Reactome: R-HSA-5334118 "Deposition of new CENPA-containing nucleosomes at the centromere";"Cleavage of the damaged purine";"Meiotic synapsis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"B-WICH complex positively regulates rRNA expression";"G2/M DNA damage checkpoint";"RNA Polymerase I Promoter Opening";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"HCMV Early Events";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"RNA Polymerase I Promoter Escape";"Estrogen-dependent gene expression";"NoRC negatively regulates rRNA expression";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"Formation of the beta-catenin:TCF transactivating complex";"Meiotic recombination";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SIRT1 negatively regulates rRNA expression";"Transcriptional regulation of granulopoiesis";"HATs acetylate histones";"PKMTs methylate histone lysines";"Pre-NOTCH Transcription and Translation";"Recognition and association of DNA glycosylase with site containing an affected purine";"Transcriptional regulation by small RNAs";"Amyloid fiber formation";"RMTs methylate histone arginines";"DNA Damage/Telomere Stress Induced Senescence";"Oxidative Stress Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Cleavage of the damaged pyrimidine";"Condensation of Prophase Chromosomes";"HDMs demethylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Senescence-Associated Secretory Phenotype (SASP)";"HDACs deacetylate histones";"HCMV Late Events";"Packaging Of Telomere Ends";"DNA methylation" XP_037822504.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037827157.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_037812992.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037824650.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037819272.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_037826366.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037809921.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_037822589.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_037823766.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_037823655.1 6 Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-434316 "Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion" XP_037817889.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037825645.1 10 Reactome: R-HSA-2565942;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5684264;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664 "Regulation of PLK1 Activity at G2/M Transition";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation" XP_037814115.1 12 KEGG: 00710+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-5484;Reactome: R-HSA-70171;Reactome: R-HSA-70263;KEGG: 00680+4.1.2.13;MetaCyc: PWY-1861;KEGG: 00030+4.1.2.13;KEGG: 00051+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-6142;KEGG: 00010+4.1.2.13 "Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Gluconeogenesis";"Methane metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis" XP_037810193.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037810514.1 13 MetaCyc: PWY-5108;MetaCyc: PWY-5132;KEGG: 00010+6.2.1.1;KEGG: 00630+6.2.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-6672;KEGG: 00720+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00680+6.2.1.1;Reactome: R-HSA-71384;KEGG: 00640+6.2.1.1;MetaCyc: PWY-5133;KEGG: 00620+6.2.1.1 "L-isoleucine biosynthesis V";"Lupulone and humulone biosynthesis";"Glycolysis / Gluconeogenesis";"Glyoxylate and dicarboxylate metabolism";"Chitin degradation to ethanol";"Cis-genanyl-coa degradation";"Carbon fixation pathways in prokaryotes";"Adlupulone and adhumulone biosynthesis";"Methane metabolism";"Ethanol oxidation";"Propanoate metabolism";"Colupulone and cohumulone biosynthesis";"Pyruvate metabolism" XP_037806456.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037811620.1 5 Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-109704 "Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"PI3K Cascade" XP_037807943.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689603 "Ub-specific processing proteases";"UCH proteinases" XP_037812090.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037817193.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_037808788.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037820260.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037822962.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1 "Hedgehog 'off' state";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"PKA activation";"G alpha (z) signalling events";"Purine metabolism" XP_037826162.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037820502.1 1 Reactome: R-HSA-70171 "Glycolysis" XP_037828817.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037823548.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037809261.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_037818458.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037819588.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_037826816.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037823179.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_037823375.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_037807632.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_037809231.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_037821764.1 44 Reactome: R-HSA-6811558;Reactome: R-HSA-5674135;Reactome: R-HSA-1295596;Reactome: R-HSA-5654726;Reactome: R-HSA-202670;Reactome: R-HSA-444257;Reactome: R-HSA-5654733;Reactome: R-HSA-74749;Reactome: R-HSA-2559582;Reactome: R-HSA-5663213;Reactome: R-HSA-8940973;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-881907;Reactome: R-HSA-445144;Reactome: R-HSA-5668599;Reactome: R-HSA-5654727;Reactome: R-HSA-112409;Reactome: R-HSA-9627069;Reactome: R-HSA-5675221;Reactome: R-HSA-5654732;Reactome: R-HSA-5674499;Reactome: R-HSA-456926;Reactome: R-HSA-6802952;Reactome: R-HSA-2871796;Reactome: R-HSA-982772;Reactome: R-HSA-2029482;Reactome: R-HSA-6802946;Reactome: R-HSA-879415;Reactome: R-HSA-375165;Reactome: R-HSA-9649948;Reactome: R-HSA-198753;Reactome: R-HSA-5673001;Reactome: R-HSA-8943724;Reactome: R-HSA-9634638;Reactome: R-HSA-6802948;Reactome: R-HSA-450341;Reactome: R-HSA-6802955;Reactome: R-HSA-162658;KEGG: 04150+2.7.11.24;Reactome: R-HSA-3371453;Reactome: R-HSA-9635465;Reactome: R-HSA-170968;Reactome: R-HSA-8939211 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"MAP2K and MAPK activation";"Spry regulation of FGF signaling";"Negative regulation of FGFR1 signaling";"ERKs are inactivated";"RSK activation";"Negative regulation of FGFR4 signaling";"Signal attenuation";"Senescence-Associated Secretory Phenotype (SASP)";"RHO GTPases Activate WASPs and WAVEs";"RUNX2 regulates osteoblast differentiation";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"Gastrin-CREB signalling pathway via PKC and MAPK";"Signal transduction by L1";"RHO GTPases Activate NADPH Oxidases";"Negative regulation of FGFR2 signaling";"RAF-independent MAPK1/3 activation";"Regulation of the apoptosome activity";"Negative regulation of MAPK pathway";"Negative regulation of FGFR3 signaling";"Negative feedback regulation of MAPK pathway";"Thrombin signalling through proteinase activated receptors (PARs)";"Signaling by BRAF and RAF fusions";"FCERI mediated MAPK activation";"Growth hormone receptor signaling";"Regulation of actin dynamics for phagocytic cup formation";"Signaling by moderate kinase activity BRAF mutants";"Advanced glycosylation endproduct receptor signaling";"NCAM signaling for neurite out-growth";"Signaling downstream of RAS mutants";"ERK/MAPK targets";"RAF/MAP kinase cascade";"Regulation of PTEN gene transcription";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Signaling by high-kinase activity BRAF mutants";"Activation of the AP-1 family of transcription factors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Golgi Cisternae Pericentriolar Stack Reorganization";"mTOR signaling pathway";"Regulation of HSF1-mediated heat shock response";"Suppression of apoptosis";"Frs2-mediated activation";"ESR-mediated signaling" XP_037819458.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_037820663.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_037824773.1 6 KEGG: 00760+6.3.5.1;MetaCyc: PWY-7761;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5653;MetaCyc: PWY-5381;Reactome: R-HSA-196807 "Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism" XP_037820686.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037815272.1 3 KEGG: 00790+1.1.1.153;Reactome: R-HSA-203615;Reactome: R-HSA-1474151 "Folate biosynthesis";"eNOS activation";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_037810785.1 14 Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593 "Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity" XP_037807308.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037821088.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_037811756.1 13 Reactome: R-HSA-2024101;Reactome: R-HSA-2022857;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52 "CS/DS degradation";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation" XP_037810711.1 2 KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23 "Pyrimidine metabolism";"Drug metabolism - other enzymes" XP_037817180.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037817981.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037820121.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037806855.1 7 KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis" XP_037825039.1 4 KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-6483;MetaCyc: PWY-7119 "Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)" XP_037826338.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_037815893.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037809334.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037818375.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037812433.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037816199.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_037813516.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_037821902.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213 "Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs" XP_037820106.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-75953 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation" XP_037820103.1 14 KEGG: 00561+2.3.1.51;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-8055;MetaCyc: PWY-7417;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-5981;MetaCyc: PWY-7589;MetaCyc: PWY-8053;MetaCyc: PWY-7411 "Glycerolipid metabolism";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Synthesis of PA";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)" XP_037820454.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_037807339.1 1 Reactome: R-HSA-419771 "Opsins" XP_037818993.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037824534.1 10 Reactome: R-HSA-9635644;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-5689880;Reactome: R-HSA-917729;Reactome: R-HSA-8856828;Reactome: R-HSA-432720;Reactome: R-HSA-182971;Reactome: R-HSA-9636383;Reactome: R-HSA-8856825 "Inhibition of membrane repair";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Ub-specific processing proteases";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"EGFR downregulation";"Prevention of phagosomal-lysosomal fusion";"Cargo recognition for clathrin-mediated endocytosis" XP_037807074.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_037818699.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597 "Hedgehog 'off' state";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"PKA activation";"Glucagon signaling in metabolic regulation";"Purine metabolism";"G alpha (z) signalling events" XP_037808641.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037817909.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_037828082.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_037822800.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037819133.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_037820072.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037810198.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037806919.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_037809197.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037823901.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation" XP_037824093.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037826939.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_037825967.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_037805646.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6783310 "Protein ubiquitination";"Fanconi Anemia Pathway" XP_037818963.1 6 Reactome: R-HSA-5632684;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-201722;Reactome: R-HSA-75955 "Hedgehog 'on' state";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Transcription Elongation" XP_037811076.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037827875.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_037819149.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037817359.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037820632.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037828025.1 6 MetaCyc: PWY-6317;Reactome: R-HSA-5609978;KEGG: 00520+2.7.7.12;MetaCyc: PWY-6527;KEGG: 00052+2.7.7.12;Reactome: R-HSA-70370 "D-galactose degradation I (Leloir pathway)";"Defective GALT can cause Galactosemia";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Galactose metabolism";"Galactose catabolism" XP_037812772.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037823801.1 4 Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-381771 "Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" XP_037817473.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037805551.1 11 Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-3214847;Reactome: R-HSA-674695;Reactome: R-HSA-5689880;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167162 "RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"HIV Transcription Initiation";"HATs acetylate histones";"RNA Polymerase II Pre-transcription Events";"Ub-specific processing proteases";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape" XP_037809708.1 6 KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107 "Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism" XP_037816689.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037826471.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_037806989.1 3 Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160 "VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions" XP_037807834.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_037816619.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" XP_037806774.1 7 KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway" XP_037810405.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037818294.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_037807345.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037806692.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_037811916.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037828154.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_037821002.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054 "HDACs deacetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway" XP_037814057.1 4 Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878 "COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-mediated anterograde transport" XP_037813372.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_037827936.1 6 Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-8951430 "Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling" XP_037807352.1 4 Reactome: R-HSA-189451;MetaCyc: PWY-5188;MetaCyc: PWY-5189;KEGG: 00860+2.5.1.61 "Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism" XP_037825367.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037817265.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037805698.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037813648.1 10 Reactome: R-HSA-8948751;Reactome: R-HSA-8934903;Reactome: R-HSA-201688;Reactome: R-HSA-445144;Reactome: R-HSA-6804756;Reactome: R-HSA-8939243;Reactome: R-HSA-6798695;Reactome: R-HSA-1483191;Reactome: R-HSA-6814122;Reactome: R-HSA-2514853 "Regulation of PTEN stability and activity";"Receptor Mediated Mitophagy";"WNT mediated activation of DVL";"Signal transduction by L1";"Regulation of TP53 Activity through Phosphorylation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Neutrophil degranulation";"Synthesis of PC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Condensation of Prometaphase Chromosomes" XP_037805369.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_037817746.1 10 Reactome: R-HSA-111463;Reactome: R-HSA-2151201;Reactome: R-HSA-5628897;Reactome: R-HSA-3299685;Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-611105;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-111457 "SMAC (DIABLO) binds to IAPs";"Transcriptional activation of mitochondrial biogenesis";"TP53 Regulates Metabolic Genes";"Detoxification of Reactive Oxygen Species";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"Respiratory electron transport";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"Release of apoptotic factors from the mitochondria" XP_037823785.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_037822194.1 4 KEGG: 00510+2.4.1.258;Reactome: R-HSA-4720475;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.258 "N-Glycan biosynthesis";"Defective ALG3 causes ALG3-CDG (CDG-1d)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis" XP_037821428.1 5 KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821 "Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification" XP_037825718.1 5 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-7822 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)" XP_037821866.1 2 Reactome: R-HSA-162588;Reactome: R-HSA-917729 "Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_037814427.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_037825600.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037824056.1 13 MetaCyc: PWY-561;MetaCyc: PWY-5392;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-7384;KEGG: 00020+4.2.1.2;MetaCyc: PWY-7254;MetaCyc: PWY-6728;MetaCyc: PWY-5913;MetaCyc: PWY-8086;KEGG: 00620+4.2.1.2;KEGG: 00720+4.2.1.2;MetaCyc: PWY-5690 "Superpathway of glyoxylate cycle and fatty acid degradation";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)" XP_037815448.1 13 Reactome: R-HSA-1489509;Reactome: R-HSA-4086398;Reactome: R-HSA-5607763;Reactome: R-HSA-114508;Reactome: R-HSA-2029485;Reactome: R-HSA-5578775;Reactome: R-HSA-422356;Reactome: R-HSA-112043;Reactome: R-HSA-139853;Reactome: R-HSA-381676;Reactome: R-HSA-983695;Reactome: R-HSA-2871809;Reactome: R-HSA-5218921 "DAG and IP3 signaling";"Ca2+ pathway";"CLEC7A (Dectin-1) induces NFAT activation";"Effects of PIP2 hydrolysis";"Role of phospholipids in phagocytosis";"Ion homeostasis";"Regulation of insulin secretion";"PLC beta mediated events";"Elevation of cytosolic Ca2+ levels";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FCERI mediated Ca+2 mobilization";"VEGFR2 mediated cell proliferation" XP_037812624.1 6 Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938 "G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)" XP_037821729.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_037810529.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467 "Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs" XP_037806786.1 7 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis" XP_037813878.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037821215.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037808974.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_037822349.1 3 KEGG: 00230+1.7.3.3;KEGG: 00232+1.7.3.3;MetaCyc: PWY-5691 "Purine metabolism";"Caffeine metabolism";"Urate conversion to allantoin I" XP_037805715.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037823120.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_037822272.1 6 Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73772 "SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape" XP_037814288.1 8 MetaCyc: PWY-7179-1;Reactome: R-HSA-6798695;Reactome: R-HSA-74217;MetaCyc: PWY-6609;Reactome: R-HSA-5683826;MetaCyc: PWY-6611;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179 "Purine deoxyribonucleosides degradation II";"Neutrophil degranulation";"Purine salvage";"Adenine and adenosine salvage III";"Surfactant metabolism";"Adenine and adenosine salvage V";"Purine metabolism";"Purine deoxyribonucleosides degradation I" XP_037812073.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_037820308.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_037810049.1 3 Reactome: R-HSA-114608;Reactome: R-HSA-195399;Reactome: R-HSA-194313 "Platelet degranulation";"VEGF binds to VEGFR leading to receptor dimerization";"VEGF ligand-receptor interactions" XP_037828779.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" YP_001425542.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_037816690.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_037826907.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_037810599.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037820994.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_037812865.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_037821499.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037812270.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037822538.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_037808640.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037821131.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037828204.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037806860.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_037814862.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_037809061.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037816580.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037810833.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_037827097.1 3 KEGG: 00230+3.5.2.5;MetaCyc: PWY-5697;MetaCyc: PWY-5698 "Purine metabolism";"Allantoin degradation to ureidoglycolate I (urea producing)";"Allantoin degradation to ureidoglycolate II (ammonia producing)" XP_037813373.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_037809203.1 7 Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877 "SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase" XP_037807462.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037811891.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_037810949.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_037824463.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037806341.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7602 "Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_037823199.1 6 Reactome: R-HSA-2173796;Reactome: R-HSA-8957275;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-5626467;Reactome: R-HSA-381426 "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Post-translational protein phosphorylation";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"RHO GTPases activate IQGAPs";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_037809982.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;Reactome: R-HSA-197264;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381 "Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)" XP_037809601.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_037808571.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_037819972.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037828038.1 2 Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2 "Glycine degradation";"Glycine, serine and threonine metabolism" XP_037814245.1 19 KEGG: 00020+1.1.1.37;KEGG: 00710+1.1.1.37;Reactome: R-HSA-71403;MetaCyc: PWY-5392;KEGG: 00270+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-6728;Reactome: R-HSA-70263;MetaCyc: PWY-6969;MetaCyc: PWY-561;KEGG: 00720+1.1.1.37;KEGG: 00680+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-5913;MetaCyc: PWY-8086;MetaCyc: PWY-7383 "Citrate cycle (TCA cycle)";"Carbon fixation in photosynthetic organisms";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"Cysteine and methionine metabolism";"Formaldehyde assimilation I (serine pathway)";"Glyoxylate and dicarboxylate metabolism";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Gluconeogenesis";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Methane metabolism";"Pyruvate metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Partial TCA cycle (obligate autotrophs)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_037811152.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_037827254.1 4 KEGG: 00230+6.3.5.2;MetaCyc: PWY-7221;Reactome: R-HSA-73817;KEGG: 00983+6.3.5.2 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes" XP_037812057.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_037816070.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037813104.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037814593.1 5 Reactome: R-HSA-3108214;Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-5221030;Reactome: R-HSA-110357 "SUMOylation of DNA damage response and repair proteins";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1" XP_037821090.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037811194.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037819876.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway" XP_037814922.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037812738.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_037816167.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706 "Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037817412.1 8 Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-167590;Reactome: R-HSA-77387;Reactome: R-HSA-182218;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-9636467 "ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Nef Mediated CD4 Down-regulation";"Insulin receptor recycling";"Nef Mediated CD8 Down-regulation";"Amino acids regulate mTORC1";"Ion channel transport";"Blockage of phagosome acidification" XP_037810212.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037820633.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037822797.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72702 "Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition" XP_037820323.1 4 Reactome: R-HSA-2408522;Reactome: R-HSA-379716;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.6 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_037826628.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037809152.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_037808585.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037812494.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_037815576.1 5 Reactome: R-HSA-198323;Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-5674400 "AKT phosphorylates targets in the cytosol";"HSF1-dependent transactivation";"mTORC1-mediated signalling";"mTOR signalling";"Constitutive Signaling by AKT1 E17K in Cancer" XP_037816305.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_037820830.1 2 Reactome: R-HSA-446193;Reactome: R-HSA-4549349 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG2 causes ALG2-CDG (CDG-1i)" XP_037814384.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037827839.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_037827282.1 4 MetaCyc: PWY-5041;Reactome: R-HSA-156581;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912 "S-adenosyl-L-methionine cycle II";"Methylation";"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis" XP_037811630.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_037819245.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037823186.1 7 Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;MetaCyc: PWY-7511 "NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Protein ubiquitination" XP_037827396.1 3 Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654 "Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_037828630.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_037826631.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037821148.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination" XP_037819066.1 5 KEGG: 00562+3.1.3.36;KEGG: 04070+3.1.3.36;Reactome: R-HSA-8856828;MetaCyc: PWY-6368;Reactome: R-HSA-1660499 "Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Clathrin-mediated endocytosis";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane" XP_037824721.1 3 Reactome: R-HSA-1268020;Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Mitochondrial protein import";"Complex I biogenesis";"Respiratory electron transport" XP_037814423.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_037815583.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_037814781.1 5 Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-427413 "RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression" XP_037821971.1 4 Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22;KEGG: 00790+4.6.1.17;MetaCyc: PWY-6823 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" XP_037816051.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_037817878.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037817332.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_037808041.1 4 Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_037807786.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_037820447.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_037807051.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation" XP_037807618.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_037808776.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689 "Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits" XP_037825882.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_037815894.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037821670.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_037827413.1 11 KEGG: 00630+6.3.1.2;MetaCyc: PWY-381;MetaCyc: PWY-5675;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6549;Reactome: R-HSA-8964539;Reactome: R-HSA-210455;MetaCyc: PWY-6964;KEGG: 00220+6.3.1.2;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6963 "Glyoxylate and dicarboxylate metabolism";"Nitrate reduction II (assimilatory)";"Nitrate reduction V (assimilatory)";"Nitrogen metabolism";"L-glutamine biosynthesis III";"Glutamate and glutamine metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Ammonia assimilation cycle II";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I" XP_037819930.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_037808257.1 3 Reactome: R-HSA-6787450;MetaCyc: PWY-7892;MetaCyc: PWY-7887 "tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation" XP_037826395.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_037812552.1 3 Reactome: R-HSA-1362409;KEGG: 00860+1.16.3.1;Reactome: R-HSA-1268020 "Mitochondrial iron-sulfur cluster biogenesis";"Porphyrin and chlorophyll metabolism";"Mitochondrial protein import" XP_037815083.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037808639.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037819242.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037805702.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037826057.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037818729.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037818309.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_037827180.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_037806564.1 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" XP_037825199.1 13 Reactome: R-HSA-202433;Reactome: R-HSA-2871809;MetaCyc: PWY-6367;Reactome: R-HSA-2871796;MetaCyc: PWY-6351;Reactome: R-HSA-9027277;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;Reactome: R-HSA-2424491;Reactome: R-HSA-2029485;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052 "Generation of second messenger molecules";"FCERI mediated Ca+2 mobilization";"D-myo-inositol-5-phosphate metabolism";"FCERI mediated MAPK activation";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"DAP12 signaling";"Role of phospholipids in phagocytosis";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis" XP_037823750.1 16 Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-7003;MetaCyc: PWY-1622;KEGG: 00680+4.2.1.11;MetaCyc: PWY-6142;MetaCyc: PWY-6901;MetaCyc: PWY-2221;Reactome: R-HSA-70171;MetaCyc: PWY-7124;MetaCyc: PWY-8004;MetaCyc: PWY-1042;MetaCyc: PWY-6886;MetaCyc: PWY-7218;MetaCyc: PWY-5723;KEGG: 00010+4.2.1.11 "Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis";"Ethylene biosynthesis V (engineered)";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"Glycolysis / Gluconeogenesis" XP_037811914.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037805587.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037814179.1 9 Reactome: R-HSA-2871796;Reactome: R-HSA-2871809;Reactome: R-HSA-416482;Reactome: R-HSA-2029482;Reactome: R-HSA-5218920;Reactome: R-HSA-4420097;Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-114604 "FCERI mediated MAPK activation";"FCERI mediated Ca+2 mobilization";"G alpha (12/13) signalling events";"Regulation of actin dynamics for phagocytic cup formation";"VEGFR2 mediated vascular permeability";"VEGFA-VEGFR2 Pathway";"NRAGE signals death through JNK";"Rho GTPase cycle";"GPVI-mediated activation cascade" XP_037814225.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037812034.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_037817826.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037823756.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_037805628.1 4 Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-73762 "Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation" XP_037823724.1 4 Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin" XP_037810340.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_037812741.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_037814154.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_037817789.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037810910.1 5 Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-5250924 "RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression" XP_037826630.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037824743.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037809658.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037814934.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_037813669.1 7 Reactome: R-HSA-381070;Reactome: R-HSA-381042;Reactome: R-HSA-114608;Reactome: R-HSA-381033;Reactome: R-HSA-983170;Reactome: R-HSA-381183;Reactome: R-HSA-3371453 "IRE1alpha activates chaperones";"PERK regulates gene expression";"Platelet degranulation";"ATF6 (ATF6-alpha) activates chaperones";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperone genes";"Regulation of HSF1-mediated heat shock response" XP_037820267.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284 "AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_037817351.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037813322.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_037820598.1 10 MetaCyc: PWY-3841;MetaCyc: PWY-7198;Reactome: R-HSA-499943;MetaCyc: PWY-7184;KEGG: 00670+2.1.1.45;Reactome: R-HSA-69205;MetaCyc: PWY-7210;MetaCyc: PWY-7187;MetaCyc: PWY-7199;KEGG: 00240+2.1.1.45 "Folate transformations II (plants)";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"One carbon pool by folate";"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine metabolism" XP_037828794.1 10 Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-3108214 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"SUMOylation of DNA damage response and repair proteins" XP_037818998.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_037819114.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037816067.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037818379.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037814220.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037825422.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_037826365.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037816905.1 5 Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-5674400 "VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer" XP_037806798.1 7 Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-177929 "Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Signaling by EGFR" XP_037827570.1 2 Reactome: R-HSA-1482798;Reactome: R-HSA-1268020 "Acyl chain remodeling of CL";"Mitochondrial protein import" XP_037823450.1 19 Reactome: R-HSA-8964041;Reactome: R-HSA-5686938;Reactome: R-HSA-8963901;Reactome: R-HSA-8964046;Reactome: R-HSA-3000471;Reactome: R-HSA-8957275;Reactome: R-HSA-3000480;Reactome: R-HSA-8856825;Reactome: R-HSA-381426;Reactome: R-HSA-8856828;Reactome: R-HSA-975634;Reactome: R-HSA-8963888;Reactome: R-HSA-202733;Reactome: R-HSA-8964026;Reactome: R-HSA-8866423;Reactome: R-HSA-3000484;Reactome: R-HSA-8964038;Reactome: R-HSA-3000497;Reactome: R-HSA-432142 "LDL remodeling";"Regulation of TLR by endogenous ligand";"Chylomicron remodeling";"VLDL clearance";"Scavenging by Class B Receptors";"Post-translational protein phosphorylation";"Scavenging by Class A Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Clathrin-mediated endocytosis";"Retinoid metabolism and transport";"Chylomicron assembly";"Cell surface interactions at the vascular wall";"Chylomicron clearance";"VLDL assembly";"Scavenging by Class F Receptors";"LDL clearance";"Scavenging by Class H Receptors";"Platelet sensitization by LDL" XP_037827983.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7619 "Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis" XP_037807038.1 18 Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-77075;Reactome: R-HSA-113418 "Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex" XP_037809448.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037822705.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-9615710 "Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Budding and maturation of HIV virion";"Late endosomal microautophagy" XP_037819742.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_037805312.1 3 Reactome: R-HSA-8853383;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.25 "Lysosomal oligosaccharide catabolism";"Neutrophil degranulation";"Other glycan degradation" XP_037812732.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_037811632.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_037817314.1 4 KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;MetaCyc: PWY-7221;Reactome: R-HSA-499943 "Purine metabolism";"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates" XP_037814855.1 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" XP_037821500.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037828615.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-2408557 "Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Viral mRNA Translation";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis" XP_037815747.1 2 Reactome: R-HSA-204174;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid" XP_037811989.1 2 Reactome: R-HSA-456926;Reactome: R-HSA-416482 "Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events" XP_037806994.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_037810320.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"RHO GTPases Activate Formins";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_037828287.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_037823297.1 18 KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-7409;Reactome: R-HSA-1483166;MetaCyc: PWY-7416;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4 "Linoleic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Ether lipid metabolism";"Acyl chain remodelling of PC";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Synthesis of PA";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Plasmalogen degradation";"alpha-Linolenic acid metabolism" XP_037828889.1 7 MetaCyc: PWY-7176;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00240+2.7.4.14;Reactome: R-HSA-499943;KEGG: 00983+2.7.4.14;KEGG: 00230+2.7.4.3 "UTP and CTP de novo biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Purine metabolism" YP_001425545.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037812768.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037822956.1 6 Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-210500 "Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle" XP_037827322.1 3 MetaCyc: PWY-7800;MetaCyc: PWY-7799;Reactome: R-HSA-2514859 "Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)";"Inactivation, recovery and regulation of the phototransduction cascade" XP_037821213.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037828762.1 14 Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5687128;Reactome: R-HSA-69273;Reactome: R-HSA-2173788;Reactome: R-HSA-9648025;Reactome: R-HSA-165054;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-3769402;Reactome: R-HSA-9634638;Reactome: R-HSA-168333;Reactome: R-HSA-450520 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"MAPK6/MAPK4 signaling";"Cyclin A/B1/B2 associated events during G2/M transition";"Downregulation of TGF-beta receptor signaling";"EML4 and NUDC in mitotic spindle formation";"Rev-mediated nuclear export of HIV RNA";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Deactivation of the beta-catenin transactivating complex";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"NEP/NS2 Interacts with the Cellular Export Machinery";"HuR (ELAVL1) binds and stabilizes mRNA" XP_037809917.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_037819091.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037807392.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7035;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7601 "Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_037821790.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_037808043.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_037819522.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037828884.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_037819107.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037812112.1 56 Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-68949;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-8854050;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-2871837;Reactome: R-HSA-180534;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974 "Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"FCERI mediated NF-kB activation";"Vpu mediated degradation of CD4";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway" XP_037816052.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_037806251.1 11 Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-418555 "Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"PKA activation";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Purine metabolism";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events" XP_037806296.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037811304.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037808849.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_037811920.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037811373.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_037824919.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_037805901.1 6 MetaCyc: PWY-7395;MetaCyc: PWY-7077;KEGG: 00052+3.5.1.25;Reactome: R-HSA-446210;MetaCyc: PWY-6906;KEGG: 00520+3.5.1.25 "D-galactosamine and N-acetyl-D-galactosamine degradation";"N-acetyl-D-galactosamine degradation";"Galactose metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism" XP_037809561.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037814818.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037814212.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037825668.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_037805623.1 3 Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2 "Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism" XP_037815349.1 2 Reactome: R-HSA-975956;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_037811300.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037812630.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_037814816.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037810525.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037827834.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_037822757.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037807664.1 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" XP_037817042.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037817029.1 3 KEGG: 00600+3.1.4.12;MetaCyc: PWY-7277;Reactome: R-HSA-1660662 "Sphingolipid metabolism";"Sphingolipid biosynthesis (mammals)";"Glycosphingolipid metabolism" XP_037814292.1 6 KEGG: 04070+2.7.11.13;Reactome: R-HSA-114516;Reactome: R-HSA-416993;Reactome: R-HSA-76005;Reactome: R-HSA-418597;Reactome: R-HSA-5099900 "Phosphatidylinositol signaling system";"Disinhibition of SNARE formation";"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+";"G alpha (z) signalling events";"WNT5A-dependent internalization of FZD4" XP_037806142.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_037825417.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_037822917.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8869496 "Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" XP_037826190.1 3 MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783 "Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" XP_037823559.1 42 Reactome: R-HSA-912446;Reactome: R-HSA-427359;Reactome: R-HSA-3214847;Reactome: R-HSA-9616222;Reactome: R-HSA-5617472;Reactome: R-HSA-110330;Reactome: R-HSA-3214841;Reactome: R-HSA-1912408;Reactome: R-HSA-3214858;Reactome: R-HSA-977225;Reactome: R-HSA-5578749;Reactome: R-HSA-3214842;Reactome: R-HSA-2299718;Reactome: R-HSA-110329;Reactome: R-HSA-8936459;Reactome: R-HSA-2559586;Reactome: R-HSA-2559580;Reactome: R-HSA-2559582;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-9610379;Reactome: R-HSA-5334118;Reactome: R-HSA-171306;Reactome: R-HSA-606279;Reactome: R-HSA-1221632;Reactome: R-HSA-110331;Reactome: R-HSA-5625886;Reactome: R-HSA-5693565;Reactome: R-HSA-73728;Reactome: R-HSA-69473;Reactome: R-HSA-5250924;Reactome: R-HSA-110328;Reactome: R-HSA-9609690;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-73772;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-4551638;Reactome: R-HSA-8939236;Reactome: R-HSA-212300;Reactome: R-HSA-427413 "Meiotic recombination";"SIRT1 negatively regulates rRNA expression";"HATs acetylate histones";"Transcriptional regulation of granulopoiesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Recognition and association of DNA glycosylase with site containing an affected purine";"PKMTs methylate histone lysines";"Pre-NOTCH Transcription and Translation";"RMTs methylate histone arginines";"Amyloid fiber formation";"Transcriptional regulation by small RNAs";"HDMs demethylate histones";"Condensation of Prophase Chromosomes";"Cleavage of the damaged pyrimidine";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"DNA Damage/Telomere Stress Induced Senescence";"Oxidative Stress Induced Senescence";"Senescence-Associated Secretory Phenotype (SASP)";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HCMV Late Events";"DNA methylation";"Packaging Of Telomere Ends";"Deposition of new CENPA-containing nucleosomes at the centromere";"Meiotic synapsis";"Cleavage of the damaged purine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RNA Polymerase I Promoter Opening";"G2/M DNA damage checkpoint";"B-WICH complex positively regulates rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HCMV Early Events";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"RNA Polymerase I Promoter Escape";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"SUMOylation of chromatin organization proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression" XP_037815596.1 12 KEGG: 00040+2.7.7.9;KEGG: 00052+2.7.7.9;KEGG: 00500+2.7.7.9;MetaCyc: PWY-3801;KEGG: 00561+2.7.7.9;Reactome: R-HSA-3322077;MetaCyc: PWY-7343;KEGG: 00520+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-7238;MetaCyc: PWY-6527;MetaCyc: PWY-7817 "Pentose and glucuronate interconversions";"Galactose metabolism";"Starch and sucrose metabolism";"Sucrose degradation II (sucrose synthase)";"Glycerolipid metabolism";"Glycogen synthesis";"UDP-alpha-D-glucose biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate";"Sucrose biosynthesis II";"Stachyose degradation";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_037823346.1 1 Reactome: R-HSA-2468052 "Establishment of Sister Chromatid Cohesion" XP_037814426.1 1 Reactome: R-HSA-74217 "Purine salvage" XP_037816567.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037819831.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-2408557 "Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Selenocysteine synthesis" XP_037815877.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037826322.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_037806858.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" XP_037820113.1 5 Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409;Reactome: R-HSA-196108;Reactome: R-HSA-5579026 "Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis";"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)" XP_037817683.1 5 Reactome: R-HSA-164843;Reactome: R-HSA-6798695;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;Reactome: R-HSA-3270619 "2-LTR circle formation";"Neutrophil degranulation";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN" XP_037813506.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_037821650.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_037815505.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037818371.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037812163.1 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_037817465.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037828444.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_037821987.1 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" XP_037815644.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_037805792.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_037813435.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_037823920.1 4 KEGG: 00970+6.1.1.18;Reactome: R-HSA-2408522;Reactome: R-HSA-379716;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation" XP_037815722.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037806164.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037820593.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037826441.1 3 Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695 "Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation" XP_037819396.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_037817290.1 9 MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;Reactome: R-HSA-112043;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-416476 "D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events" XP_037823611.1 3 Reactome: R-HSA-6798695;MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9 "Neutrophil degranulation";"Glutamate removal from folates";"Folate biosynthesis" XP_037824040.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_037812315.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_037825930.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_037822760.1 3 Reactome: R-HSA-1236974;Reactome: R-HSA-1799339;Reactome: R-HSA-9609523 "ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_037826040.1 4 MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112;MetaCyc: PWY-4361 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_037820114.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037825224.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_037825364.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_037827840.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_037825124.1 5 MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism" XP_037816232.1 6 Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176974 "Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Unwinding of DNA" XP_037807847.1 1 MetaCyc: PWY-7379 "Mrna capping II" XP_037807372.1 1 Reactome: R-HSA-416476 "G alpha (q) signalling events" XP_037825517.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-5689880 "Protein ubiquitination";"Ub-specific processing proteases" XP_037820139.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_037827093.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_037813793.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_037824469.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037806671.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037807765.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_037821867.1 2 Reactome: R-HSA-162588;Reactome: R-HSA-917729 "Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_037813980.1 22 MetaCyc: PWY-6142;MetaCyc: PWY-7238;KEGG: 00010+5.3.1.9;Reactome: R-HSA-70263;MetaCyc: PWY-5514;MetaCyc: PWY-3801;Reactome: R-HSA-5628897;MetaCyc: PWY-8013;MetaCyc: PWY-5659;MetaCyc: PWY-5384;MetaCyc: PWY-7385;MetaCyc: PWY-622;MetaCyc: PWY-7347;KEGG: 00030+5.3.1.9;KEGG: 00520+5.3.1.9;Reactome: R-HSA-70171;MetaCyc: PWY-621;Reactome: R-HSA-6798695;MetaCyc: PWY-6981;MetaCyc: PWY-6992;KEGG: 00500+5.3.1.9;MetaCyc: PWY-5054 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Sucrose biosynthesis II";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Sucrose degradation II (sucrose synthase)";"TP53 Regulates Metabolic Genes";"UDP-N-acetyl-D-galactosamine biosynthesis III";"GDP-mannose biosynthesis";"Sucrose degradation IV (sucrose phosphorylase)";"1,3-propanediol biosynthesis (engineered)";"Starch biosynthesis";"Sucrose biosynthesis III";"Pentose phosphate pathway";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Sucrose degradation III (sucrose invertase)";"Neutrophil degranulation";"Chitin biosynthesis";"1,5-anhydrofructose degradation";"Starch and sucrose metabolism";"D-sorbitol biosynthesis I" XP_037820894.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037817931.1 27 Reactome: R-HSA-77595;Reactome: R-HSA-111367;Reactome: R-HSA-72165;Reactome: R-HSA-72086;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-6803529;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-72187;Reactome: R-HSA-159227;Reactome: R-HSA-975956;Reactome: R-HSA-167152;Reactome: R-HSA-159230;Reactome: R-HSA-975957;Reactome: R-HSA-72163;Reactome: R-HSA-8851708;Reactome: R-HSA-113418;Reactome: R-HSA-9010553;Reactome: R-HSA-191859;Reactome: R-HSA-72203;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-167200;Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-112382 "Processing of Intronless Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"mRNA Capping";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"FGFR2 alternative splicing";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA 3'-end processing";"Transport of the SLBP independent Mature mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of HIV elongation complex in the absence of HIV Tat";"Transport of the SLBP Dependant Mature mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Splicing - Major Pathway";"Signaling by FGFR2 IIIa TM";"Formation of the Early Elongation Complex";"Regulation of expression of SLITs and ROBOs";"snRNP Assembly";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Formation of RNA Pol II elongation complex" XP_037824176.1 18 KEGG: 00983+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7224;MetaCyc: PWY-7176;MetaCyc: PWY-7197;MetaCyc: PWY-7187;MetaCyc: PWY-6545;KEGG: 00230+2.7.4.6;Reactome: R-HSA-499943;MetaCyc: PWY-7227;MetaCyc: PWY-7221;MetaCyc: PWY-7226;MetaCyc: PWY-7210;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7205;MetaCyc: PWY-7198;MetaCyc: PWY-7184 "Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I" XP_037823470.1 8 MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083633;Reactome: R-HSA-5173105;MetaCyc: PWY-7922;Reactome: R-HSA-5083629;KEGG: 00514+2.4.1.109 "Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Other types of O-glycan biosynthesis" XP_037814552.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037826337.1 20 MetaCyc: PWY-7340;MetaCyc: PWY-7726;MetaCyc: PWY-7858;MetaCyc: PWY-6920;MetaCyc: PWY-7288;KEGG: 00592+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-735;MetaCyc: PWY-5136;MetaCyc: PWY-6837;MetaCyc: PWY-7338;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7854;MetaCyc: PWY-7574;Reactome: R-HSA-9033241;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7007 "9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(5Z)-dodecenoate biosynthesis II";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoyl-coa degradation II";"Peroxisomal protein import";"beta-Alanine metabolism";"Methyl ketone biosynthesis (engineered)" XP_037806143.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_037815175.1 24 Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;KEGG: 04150+2.7.11.1;Reactome: R-HSA-114604;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-2730905;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-2871837;Reactome: R-HSA-5218920;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-5607764;Reactome: R-HSA-165158;Reactome: R-HSA-5625740;Reactome: R-HSA-9634635;Reactome: R-HSA-392451;Reactome: R-HSA-202424;Reactome: R-HSA-444257;KEGG: 04714+2.7.11.1 "Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"mTOR signaling pathway";"GPVI-mediated activation cascade";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"VEGFR2 mediated cell proliferation";"Role of LAT2/NTAL/LAB on calcium mobilization";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Integrin signaling";"FCERI mediated NF-kB activation";"VEGFR2 mediated vascular permeability";"Human cytomegalovirus infection";"PIP3 activates AKT signaling";"CLEC7A (Dectin-1) signaling";"Activation of AKT2";"RHO GTPases activate PKNs";"Estrogen-stimulated signaling through PRKCZ";"G beta:gamma signalling through PI3Kgamma";"Downstream TCR signaling";"RSK activation";"Thermogenesis" XP_037814573.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037806339.1 14 KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7035 "Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis" XP_037817498.1 5 MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979 "Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)" XP_037818822.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037828214.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037806869.1 7 KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway" XP_037814329.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_037828009.1 1 Reactome: R-HSA-196836 "Vitamin C (ascorbate) metabolism" XP_037807001.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_037823904.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_037814098.1 12 KEGG: 00680+4.1.2.13;MetaCyc: PWY-1861;Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00710+4.1.2.13;MetaCyc: PWY-6142;KEGG: 00010+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00051+4.1.2.13;KEGG: 00030+4.1.2.13 "Methane metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gluconeogenesis";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Pentose phosphate pathway" XP_037809153.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_037828162.1 28 Reactome: R-HSA-174437;Reactome: R-HSA-110312;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-69166;Reactome: R-HSA-6782135;Reactome: R-HSA-5693616;Reactome: R-HSA-3371511;Reactome: R-HSA-5693607;Reactome: R-HSA-5358565;Reactome: R-HSA-6804756;Reactome: R-HSA-68962;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-3371453;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-110320;Reactome: R-HSA-912446;Reactome: R-HSA-5358606;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-69473;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169 "Removal of the Flap Intermediate from the C-strand";"Translesion synthesis by REV1";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Removal of the Flap Intermediate";"Dual incision in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"HSF1 activation";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Regulation of TP53 Activity through Phosphorylation";"Activation of the pre-replicative complex";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Regulation of HSF1-mediated heat shock response";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion Synthesis by POLH";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis" XP_037828684.1 3 KEGG: 00030+1.1.1.44;KEGG: 00480+1.1.1.44;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Glutathione metabolism";"Pentose phosphate pathway" XP_037815433.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037820514.1 3 Reactome: R-HSA-499943;MetaCyc: PWY-7210;KEGG: 00240+3.5.4.12 "Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism" XP_037806112.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037813651.1 10 Reactome: R-HSA-8948751;Reactome: R-HSA-8939243;Reactome: R-HSA-1483191;Reactome: R-HSA-6798695;Reactome: R-HSA-8934903;Reactome: R-HSA-445144;Reactome: R-HSA-201688;Reactome: R-HSA-6804756;Reactome: R-HSA-2514853;Reactome: R-HSA-6814122 "Regulation of PTEN stability and activity";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Synthesis of PC";"Neutrophil degranulation";"Receptor Mediated Mitophagy";"Signal transduction by L1";"WNT mediated activation of DVL";"Regulation of TP53 Activity through Phosphorylation";"Condensation of Prometaphase Chromosomes";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_037816487.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-6791226 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Viral mRNA Translation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037809710.1 5 Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68949 "Activation of the pre-replicative complex";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin" XP_037820654.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" XP_037818276.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_037812793.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037809082.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_037813743.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037809881.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037808602.1 3 Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_037820616.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037818462.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_037820998.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_037815743.1 2 Reactome: R-HSA-204174;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid" XP_037816641.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-5663220 "Signaling by ROBO receptors";"RHO GTPases Activate Formins" XP_037807630.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_037811684.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037824995.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037806480.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection" XP_037816308.1 3 KEGG: 00534+5.1.3.17;MetaCyc: PWY-6558;Reactome: R-HSA-2022928 "Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis" XP_037814572.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037822717.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037807950.1 14 Reactome: R-HSA-8934593;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-8943723 "Regulation of RUNX1 Expression and Activity";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation" XP_037824771.1 5 KEGG: 00513+2.4.1.68;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.68;MetaCyc: PWY-7426;KEGG: 00533+2.4.1.68 "Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Glycosaminoglycan biosynthesis - keratan sulfate" XP_037816180.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_037822737.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037821071.1 6 KEGG: 00564+1.1.5.3;MetaCyc: PWY-6952;Reactome: R-HSA-163560;MetaCyc: PWY-6118;MetaCyc: PWY-4261;Reactome: R-HSA-1483166 "Glycerophospholipid metabolism";"Glycerophosphodiester degradation";"Triglyceride catabolism";"Glycerol-3-phosphate shuttle";"Glycerol degradation I";"Synthesis of PA" XP_037817565.1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_037827261.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_037818376.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037821390.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_037812629.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_037826917.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037825888.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037818973.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_037807204.1 2 Reactome: R-HSA-70895;KEGG: 00280+1.3.8.4 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" XP_037808942.1 3 MetaCyc: PWY-7799;MetaCyc: PWY-7800;Reactome: R-HSA-2514859 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade" XP_037805379.1 10 KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855167;MetaCyc: PWY-6361;MetaCyc: PWY-4661;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-6554;MetaCyc: PWY-6372;MetaCyc: PWY-6362;MetaCyc: PWY-6369 "Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol diphosphates biosynthesis" XP_037813728.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037826599.1 16 Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-141430;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-2559582 "Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)" XP_037805791.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_037827969.1 3 Reactome: R-HSA-77588;Reactome: R-HSA-159230;Reactome: R-HSA-73856 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination" XP_037827659.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_037826421.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107 "Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system" XP_037806896.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_037812116.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_037812682.1 3 KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639;KEGG: 00520+1.1.1.271 "Fructose and mannose metabolism";"GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_037813012.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_037808918.1 6 Reactome: R-HSA-73930;Reactome: R-HSA-110357;Reactome: R-HSA-110362;Reactome: R-HSA-5651801;Reactome: R-HSA-73933;Reactome: R-HSA-110373 "Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Displacement of DNA glycosylase by APEX1";"POLB-Dependent Long Patch Base Excision Repair";"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of Abasic Sites (AP sites)";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway" XP_037828250.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037826281.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037817645.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037810536.1 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_037810769.1 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_037821423.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037809966.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037820578.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_037809986.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;Reactome: R-HSA-197264;MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21 "Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism" XP_037816159.1 14 MetaCyc: PWY-6453;Reactome: R-HSA-8931987;Reactome: R-HSA-1483166;Reactome: R-HSA-9018519;MetaCyc: PWY-8055;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-7411;Reactome: R-HSA-75109;KEGG: 00564+2.3.1.15;Reactome: R-HSA-2426168;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-5667 "Stigma estolide biosynthesis";"RUNX1 regulates estrogen receptor mediated transcription";"Synthesis of PA";"Estrogen-dependent gene expression";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Triglyceride biosynthesis";"Glycerophospholipid metabolism";"Activation of gene expression by SREBF (SREBP)";"Glycerolipid metabolism";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I" XP_037815137.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_037827850.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_037805470.1 10 Reactome: R-HSA-2453864;MetaCyc: PWY-7849;Reactome: R-HSA-3000171;Reactome: R-HSA-977225;Reactome: R-HSA-2453902;MetaCyc: PWY-5691;KEGG: 00230+3.5.2.17;Reactome: R-HSA-6798695;MetaCyc: PWY-7394;Reactome: R-HSA-975634 "Retinoid cycle disease events";"Urate conversion to allantoin III";"Non-integrin membrane-ECM interactions";"Amyloid fiber formation";"The canonical retinoid cycle in rods (twilight vision)";"Urate conversion to allantoin I";"Purine metabolism";"Neutrophil degranulation";"Urate conversion to allantoin II";"Retinoid metabolism and transport" XP_037818604.1 7 Reactome: R-HSA-9010553;Reactome: R-HSA-5083628;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629 "Regulation of expression of SLITs and ROBOs";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2" XP_037810272.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037809106.1 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" XP_037819898.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037824553.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037821450.1 19 Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-9617324;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-5673000;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-438066 "Interferon gamma signaling";"HSF1-dependent transactivation";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"RAF activation";"RAF/MAP kinase cascade";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation" XP_037821535.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037805774.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_037811752.1 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" XP_037821845.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037822751.1 6 Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68867 "Unwinding of DNA";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex" XP_037818012.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_037826752.1 6 KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23 "Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation" XP_037818080.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_037814209.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037815862.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037810432.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_037816125.1 6 Reactome: R-HSA-71240;MetaCyc: PWY-5651;MetaCyc: PWY-6309;MetaCyc: PWY-7717;MetaCyc: PWY-7765;KEGG: 00380+1.14.13.9 "Tryptophan catabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"L-tryptophan degradation XI (mammalian, via kynurenine)";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan metabolism" XP_037807069.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_037817150.1 6 Reactome: R-HSA-9033241;KEGG: 00630+1.11.1.6;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;Reactome: R-HSA-6798695 "Peroxisomal protein import";"Glyoxylate and dicarboxylate metabolism";"Tryptophan metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Neutrophil degranulation" XP_037828303.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037819997.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" XP_037815983.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-1834949 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA" XP_037828029.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037824057.1 13 MetaCyc: PWY-6969;MetaCyc: PWY-7254;MetaCyc: PWY-7384;KEGG: 00020+4.2.1.2;MetaCyc: PWY-561;MetaCyc: PWY-5392;Reactome: R-HSA-71403;MetaCyc: PWY-5690;KEGG: 00720+4.2.1.2;MetaCyc: PWY-5913;MetaCyc: PWY-6728;KEGG: 00620+4.2.1.2;MetaCyc: PWY-8086 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle VII (acetate-producers)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen" XP_037819797.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037814732.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_037818395.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_037810675.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_037814299.1 6 Reactome: R-HSA-1650814;Reactome: R-HSA-8874081;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-3000171;Reactome: R-HSA-8948216 "Collagen biosynthesis and modifying enzymes";"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Non-integrin membrane-ECM interactions";"Collagen chain trimerization" XP_037823255.1 3 Reactome: R-HSA-4419969;Reactome: R-HSA-2995383;Reactome: R-HSA-2980766 "Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown" XP_037819175.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_037827554.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037810699.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_037811824.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_037806243.1 5 MetaCyc: PWY-7176;MetaCyc: PWY-7185;Reactome: R-HSA-499943;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7177 "UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"UTP and CTP dephosphorylation II" XP_037805308.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037809122.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004 "Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity" XP_037817299.1 9 MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;Reactome: R-HSA-112043;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;Reactome: R-HSA-416476 "D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"G alpha (q) signalling events" XP_037813973.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037828632.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_037822267.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037814850.1 3 Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-1358803 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling" XP_037818635.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation" XP_037808638.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037812175.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_037807908.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_037813013.1 9 Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-76042 "RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_037810135.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-2173788 "UCH proteinases";"Downregulation of TGF-beta receptor signaling" XP_037805739.1 2 Reactome: R-HSA-176187;Reactome: R-HSA-68962 "Activation of ATR in response to replication stress";"Activation of the pre-replicative complex" XP_037818629.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037813984.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037807412.1 14 MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7724;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7602 "Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_037807590.1 20 Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-174411;Reactome: R-HSA-69473;Reactome: R-HSA-5656121;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-6782135;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-110312;Reactome: R-HSA-69091 "Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching on the C-strand of the telomere";"G2/M DNA damage checkpoint";"Translesion synthesis by POLI";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual incision in TC-NER";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by REV1";"Polymerase switching" YP_001425547.1 7 Reactome: R-HSA-6799198;MetaCyc: PWY-6692;MetaCyc: PWY-3781;MetaCyc: PWY-5083;MetaCyc: PWY-4302;Reactome: R-HSA-611105;KEGG: 00190+7.1.1.2 "Complex I biogenesis";"Fe(II) oxidation";"Aerobic respiration I (cytochrome c)";"NAD/NADH phosphorylation and dephosphorylation";"Aerobic respiration III (alternative oxidase pathway)";"Respiratory electron transport";"Oxidative phosphorylation" XP_037826067.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037816512.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_037821053.1 8 Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;MetaCyc: PWY-7980;Reactome: R-HSA-1222556;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-917977 "Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ATP biosynthesis";"ROS and RNS production in phagocytes";"Oxidative phosphorylation";"Photosynthesis";"Transferrin endocytosis and recycling" XP_037827846.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_037809065.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037822892.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037807840.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037819499.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_037812072.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_037815566.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037827134.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_037821040.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_037812162.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_037810880.1 5 Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6781827 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" XP_037825147.1 5 MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269 "NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_037818977.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_037807188.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037809992.1 5 KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-1368108;Reactome: R-HSA-6798695;Reactome: R-HSA-197264 "Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Neutrophil degranulation";"Nicotinamide salvaging" XP_037805622.1 5 Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-2132295 "Cargo concentration in the ER";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation" XP_037811356.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037818909.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037807279.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037806158.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_037818109.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037818868.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_037811747.1 5 Reactome: R-HSA-964975;Reactome: R-HSA-6798695;KEGG: 00750+2.7.1.35;MetaCyc: PWY-7282;MetaCyc: PWY-7204 "Vitamins B6 activation to pyridoxal phosphate";"Neutrophil degranulation";"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)" XP_037817739.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037826524.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037819275.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_037824598.1 3 Reactome: R-HSA-70350;Reactome: R-HSA-5657562;KEGG: 00051+2.7.1.3 "Fructose catabolism";"Essential fructosuria";"Fructose and mannose metabolism" XP_037810101.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_037827076.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_037823031.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_037813624.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_037828329.1 27 Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-180746;Reactome: R-HSA-168271 "Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus" XP_037814229.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037817326.1 2 KEGG: 00270+3.1.3.77;Reactome: R-HSA-1237112 "Cysteine and methionine metabolism";"Methionine salvage pathway" XP_037806331.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7725 "Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_037827583.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037813863.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037815710.1 5 KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527 "Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation" XP_037817386.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037819453.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_037817173.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_037828781.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037818126.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037808583.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037814313.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_037805826.1 13 Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;Reactome: R-HSA-2022857;KEGG: 00604+3.2.1.52 "Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"CS/DS degradation";"Anhydromuropeptides recycling II";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - ganglio series" XP_037817801.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037819812.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_037827895.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037810460.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_037826363.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037828639.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037814574.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037825865.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_037813638.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_037820016.1 10 MetaCyc: PWY-7661;MetaCyc: PWY-7921;KEGG: 00510+2.4.1.83;Reactome: R-HSA-162699;MetaCyc: PWY-7979;Reactome: R-HSA-4717374;Reactome: R-HSA-4719377;Reactome: R-HSA-4719360;MetaCyc: PWY-7922;Reactome: R-HSA-913709 "Protein N-glycosylation (Haloferax volcanii)";"Protein O-mannosylation I (yeast)";"N-Glycan biosynthesis";"Synthesis of dolichyl-phosphate mannose";"Protein O-mannosylation III (mammals, core M3)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"O-linked glycosylation of mucins" XP_037822700.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706 "Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037820887.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_037806244.1 5 Reactome: R-HSA-499943;MetaCyc: PWY-7177;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7185;MetaCyc: PWY-7176 "Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation II";"Pyrimidine metabolism";"UTP and CTP dephosphorylation I";"UTP and CTP de novo biosynthesis" XP_037811407.1 5 Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73772 "B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape" XP_037814821.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037814239.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037828177.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037828051.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037827013.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037826969.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_037827071.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037807331.1 3 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-383280 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nuclear Receptor transcription pathway" XP_037809922.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_037819873.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6785470 "tRNA processing in the nucleus";"tRNA processing in the mitochondrion" XP_037824357.1 4 KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"DARPP-32 events";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037811419.1 6 MetaCyc: PWY-1622;KEGG: 00260+5.4.2.11;MetaCyc: PWY-8004;KEGG: 00680+5.4.2.11;KEGG: 00010+5.4.2.11;MetaCyc: PWY-5484 "Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Entner-Doudoroff pathway I";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)" XP_037819457.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_037818623.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037822734.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037809268.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037817926.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_037812561.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_037813940.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_037812395.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037811591.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037825377.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037814783.1 3 Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import" XP_037828597.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_037826759.1 1 Reactome: R-HSA-419771 "Opsins" XP_037807733.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037810558.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_037823168.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_037806440.1 6 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_037812779.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_037825226.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" XP_037807114.1 4 Reactome: R-HSA-71240;Reactome: R-HSA-5660862;Reactome: R-HSA-210991;Reactome: R-HSA-352230 "Tryptophan catabolism";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Basigin interactions";"Amino acid transport across the plasma membrane" XP_037812309.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_037822771.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037818373.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037811449.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037820905.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037813181.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037815442.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037821147.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-2408557 "Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis" XP_037815757.1 5 Reactome: R-HSA-6798695;MetaCyc: PWY-7180;Reactome: R-HSA-71336;MetaCyc: PWY-8060;KEGG: 00030+4.1.2.4 "Neutrophil degranulation";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Pentose phosphate pathway";"2-deoxy-D-ribose degradation I";"Pentose phosphate pathway" XP_037815522.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_037820385.1 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" XP_037812059.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_037817194.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_037807438.1 4 Reactome: R-HSA-422085;KEGG: 00564+3.1.1.7;Reactome: R-HSA-112311;Reactome: R-HSA-1483191 "Synthesis, secretion, and deacylation of Ghrelin";"Glycerophospholipid metabolism";"Neurotransmitter clearance";"Synthesis of PC" XP_037822498.1 19 Reactome: R-HSA-381426;Reactome: R-HSA-8856828;Reactome: R-HSA-975634;Reactome: R-HSA-3000480;Reactome: R-HSA-8856825;Reactome: R-HSA-3000497;Reactome: R-HSA-432142;Reactome: R-HSA-202733;Reactome: R-HSA-8963888;Reactome: R-HSA-8964026;Reactome: R-HSA-8866423;Reactome: R-HSA-3000484;Reactome: R-HSA-8964038;Reactome: R-HSA-8964046;Reactome: R-HSA-3000471;Reactome: R-HSA-8964041;Reactome: R-HSA-5686938;Reactome: R-HSA-8963901;Reactome: R-HSA-8957275 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Clathrin-mediated endocytosis";"Retinoid metabolism and transport";"Scavenging by Class A Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class H Receptors";"Platelet sensitization by LDL";"Cell surface interactions at the vascular wall";"Chylomicron assembly";"Chylomicron clearance";"VLDL assembly";"Scavenging by Class F Receptors";"LDL clearance";"VLDL clearance";"Scavenging by Class B Receptors";"LDL remodeling";"Regulation of TLR by endogenous ligand";"Chylomicron remodeling";"Post-translational protein phosphorylation" XP_037806455.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037808246.1 1 Reactome: R-HSA-5250924 "B-WICH complex positively regulates rRNA expression" XP_037820666.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_037807973.1 11 MetaCyc: PWY-7560;MetaCyc: PWY-6383;MetaCyc: PWY-7524;KEGG: 00900+5.3.3.2;MetaCyc: PWY-922;MetaCyc: PWY-6174;MetaCyc: PWY-6859;Reactome: R-HSA-191273;MetaCyc: PWY-7102;MetaCyc: PWY-7391;MetaCyc: PWY-5123 "Methylerythritol phosphate pathway II";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Mevalonate pathway III (archaea)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"All-trans-farnesol biosynthesis";"Cholesterol biosynthesis";"Bisabolene biosynthesis (engineered)";"Isoprene biosynthesis II (engineered)";"Trans, trans-farnesyl diphosphate biosynthesis" XP_037806940.1 4 Reactome: R-HSA-1912420;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_037821925.1 5 Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs" XP_037806232.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037807601.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037812397.1 2 Reactome: R-HSA-977606;Reactome: R-HSA-166665 "Regulation of Complement cascade";"Terminal pathway of complement" XP_037827597.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037808540.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_037812414.1 6 Reactome: R-HSA-1650814;Reactome: R-HSA-8874081;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-3000171;Reactome: R-HSA-8948216 "Collagen biosynthesis and modifying enzymes";"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Non-integrin membrane-ECM interactions";"Collagen chain trimerization" XP_037813018.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-167161 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"HIV Transcription Initiation" XP_037813514.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_037806351.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-8041 "Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis" XP_037816691.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037805633.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_037813374.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_037824214.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_037808086.1 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" XP_037808766.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037806426.1 22 Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-5675221;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-5467348;Reactome: R-HSA-5358752;Reactome: R-HSA-9648025;Reactome: R-HSA-6811558;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-432142;Reactome: R-HSA-5358751 "Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"Truncations of AMER1 destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"RAF activation";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Platelet sensitization by LDL";"S45 mutants of beta-catenin aren't phosphorylated" XP_037818367.1 2 Reactome: R-HSA-196741;Reactome: R-HSA-3359473 "Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD" XP_037809225.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_037810613.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_037815895.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_037816096.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037807881.1 3 Reactome: R-HSA-5368286;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9 "Mitochondrial translation initiation";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis" XP_037807862.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_037813481.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-5689880 "Mitochondrial calcium ion transport";"Ub-specific processing proteases" XP_037808028.1 18 MetaCyc: PWY-6638;MetaCyc: PWY-5913;MetaCyc: PWY-7383;MetaCyc: PWY-7115;KEGG: 00960+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-6642;KEGG: 00360+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00220+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00330+2.6.1.1 "Sulfolactate degradation III";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Coenzyme M biosynthesis II";"(R)-cysteate degradation";"Phenylalanine metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Arginine biosynthesis";"Cysteine and methionine metabolism";"Alanine, aspartate and glutamate metabolism";"Novobiocin biosynthesis";"Carbon fixation in photosynthetic organisms";"Arginine and proline metabolism" XP_037812804.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037811150.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214847 "NoRC negatively regulates rRNA expression";"HATs acetylate histones" XP_037817646.1 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2299718 "Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes" XP_037824758.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037828300.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037806374.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037817466.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037817240.1 11 Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-6807878;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295 "Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"COPI-mediated anterograde transport";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation" XP_037817511.1 1 Reactome: R-HSA-390696 "Adrenoceptors" XP_037806311.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection" XP_037828264.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_037827015.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226 "Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037821400.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037814389.1 9 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_037820765.1 27 Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-3371453;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638 "Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins" XP_037824326.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037818546.1 4 Reactome: R-HSA-8874211;Reactome: R-HSA-1655829;Reactome: R-HSA-381033;Reactome: R-HSA-8963889 "CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones";"Assembly of active LPL and LIPC lipase complexes" XP_037814064.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_037812612.1 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" XP_037818701.1 11 Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-432040 "PKA activation";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (z) signalling events";"Hedgehog 'off' state";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_037813084.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-6791226 "KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037809005.1 3 MetaCyc: PWY-6823;KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" XP_037825105.1 2 KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201 "Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_037821225.1 4 MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32 "Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism" XP_037805754.1 6 KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33;Reactome: R-HSA-71403;Reactome: R-HSA-1268020;KEGG: 00020+4.2.1.3 "Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis";"Citric acid cycle (TCA cycle)";"Mitochondrial protein import";"Citrate cycle (TCA cycle)" XP_037819350.1 5 MetaCyc: PWY-4981;MetaCyc: PWY-6344;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2;MetaCyc: PWY-3341 "L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)" XP_037828146.1 7 KEGG: 00480+6.3.2.2;MetaCyc: PWY-6840;KEGG: 00270+6.3.2.2;MetaCyc: PWY-7255;Reactome: R-HSA-174403;MetaCyc: PWY-8043;Reactome: R-HSA-5578999 "Glutathione metabolism";"Homoglutathione biosynthesis";"Cysteine and methionine metabolism";"Ergothioneine biosynthesis I (bacteria)";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)" XP_037817192.1 42 Reactome: R-HSA-73728;Reactome: R-HSA-5250924;Reactome: R-HSA-69473;Reactome: R-HSA-5625886;Reactome: R-HSA-5693565;Reactome: R-HSA-110331;Reactome: R-HSA-1221632;Reactome: R-HSA-606279;Reactome: R-HSA-4551638;Reactome: R-HSA-8939236;Reactome: R-HSA-212300;Reactome: R-HSA-201722;Reactome: R-HSA-427413;Reactome: R-HSA-9018519;Reactome: R-HSA-73772;Reactome: R-HSA-110328;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-9609690;Reactome: R-HSA-3214858;Reactome: R-HSA-977225;Reactome: R-HSA-5578749;Reactome: R-HSA-3214841;Reactome: R-HSA-1912408;Reactome: R-HSA-110330;Reactome: R-HSA-5617472;Reactome: R-HSA-3214847;Reactome: R-HSA-427359;Reactome: R-HSA-9616222;Reactome: R-HSA-912446;Reactome: R-HSA-5334118;Reactome: R-HSA-171306;Reactome: R-HSA-9610379;Reactome: R-HSA-427389;Reactome: R-HSA-2559582;Reactome: R-HSA-3214815;Reactome: R-HSA-3214842;Reactome: R-HSA-2299718;Reactome: R-HSA-2559586;Reactome: R-HSA-8936459;Reactome: R-HSA-2559580;Reactome: R-HSA-110329 "RNA Polymerase I Promoter Opening";"B-WICH complex positively regulates rRNA expression";"G2/M DNA damage checkpoint";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cleavage of the damaged purine";"Meiotic synapsis";"Deposition of new CENPA-containing nucleosomes at the centromere";"SUMOylation of chromatin organization proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"PRC2 methylates histones and DNA";"Formation of the beta-catenin:TCF transactivating complex";"NoRC negatively regulates rRNA expression";"Estrogen-dependent gene expression";"RNA Polymerase I Promoter Escape";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"HCMV Early Events";"RMTs methylate histone arginines";"Amyloid fiber formation";"Transcriptional regulation by small RNAs";"PKMTs methylate histone lysines";"Pre-NOTCH Transcription and Translation";"Recognition and association of DNA glycosylase with site containing an affected purine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HATs acetylate histones";"SIRT1 negatively regulates rRNA expression";"Transcriptional regulation of granulopoiesis";"Meiotic recombination";"DNA methylation";"Packaging Of Telomere Ends";"HCMV Late Events";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Senescence-Associated Secretory Phenotype (SASP)";"HDACs deacetylate histones";"HDMs demethylate histones";"Condensation of Prophase Chromosomes";"DNA Damage/Telomere Stress Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Oxidative Stress Induced Senescence";"Cleavage of the damaged pyrimidine" XP_037814101.1 26 Reactome: R-HSA-9018519;Reactome: R-HSA-9013695;Reactome: R-HSA-8866907;Reactome: R-HSA-210744;Reactome: R-HSA-201722;Reactome: R-HSA-3899300;Reactome: R-HSA-400253;Reactome: R-HSA-1234158;Reactome: R-HSA-1912408;Reactome: R-HSA-5621575;Reactome: R-HSA-3371568;Reactome: R-HSA-3134973;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-918233;Reactome: R-HSA-9614657;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856;Reactome: R-HSA-381340;Reactome: R-HSA-9617629;Reactome: R-HSA-933541;Reactome: R-HSA-3214847;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472 "Estrogen-dependent gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Formation of the beta-catenin:TCF transactivating complex";"SUMOylation of transcription cofactors";"Circadian Clock";"Regulation of gene expression by Hypoxia-inducible Factor";"Pre-NOTCH Transcription and Translation";"CD209 (DC-SIGN) signaling";"Attenuation phase";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"TRAF3-dependent IRF activation pathway";"FOXO-mediated transcription of cell death genes";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Transcriptional regulation of white adipocyte differentiation";"Regulation of FOXO transcriptional activity by acetylation";"TRAF6 mediated IRF7 activation";"HATs acetylate histones";"RORA activates gene expression";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_037814490.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037807593.1 9 KEGG: 00980+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-6842;MetaCyc: PWY-7533;KEGG: 00480+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;MetaCyc: PWY-4061;KEGG: 00983+2.5.1.18 "Metabolism of xenobiotics by cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Gliotoxin biosynthesis";"Glutathione metabolism";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification I";"Drug metabolism - other enzymes" XP_037827824.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_037805599.1 9 Reactome: R-HSA-5649702;Reactome: R-HSA-110330;Reactome: R-HSA-9657050;Reactome: R-HSA-110331;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-9656255;Reactome: R-HSA-9656256;Reactome: R-HSA-110328 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective OGG1 Localization";"Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Defective OGG1 Substrate Binding";"Defective OGG1 Substrate Processing";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" XP_037817355.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037823742.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_037824428.1 5 Reactome: R-HSA-186763;Reactome: R-HSA-5218921;Reactome: R-HSA-3928662;Reactome: R-HSA-5658442;Reactome: R-HSA-8849471 "Downstream signal transduction";"VEGFR2 mediated cell proliferation";"EPHB-mediated forward signaling";"Regulation of RAS by GAPs";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases" XP_037827060.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037820623.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037818545.1 4 Reactome: R-HSA-8874211;Reactome: R-HSA-8963889;Reactome: R-HSA-381033;Reactome: R-HSA-1655829 "CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_037813778.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533 "Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis" XP_037810726.1 19 Reactome: R-HSA-6798695;KEGG: 00660+6.2.1.5;KEGG: 00020+6.2.1.5;Reactome: R-HSA-75105;MetaCyc: PWY-5913;MetaCyc: PWY-6969;MetaCyc: PWY-7384;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5537;KEGG: 00720+2.3.3.8;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-5538;Reactome: R-HSA-163765;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5172;MetaCyc: PWY-5392;Reactome: R-HSA-71403 "Neutrophil degranulation";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"Fatty acyl-CoA biosynthesis";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"ChREBP activates metabolic gene expression";"Propanoate metabolism";"Acetyl-coa biosynthesis III (from citrate)";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)" XP_037808959.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037814040.1 52 Reactome: R-HSA-167238;Reactome: R-HSA-72165;Reactome: R-HSA-72086;Reactome: R-HSA-76071;Reactome: R-HSA-73776;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-76066;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-76042;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-72203;Reactome: R-HSA-203927;Reactome: R-HSA-8851708;Reactome: R-HSA-167161;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-749476;Reactome: R-HSA-75955;Reactome: R-HSA-427413;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-5601884;Reactome: R-HSA-75953;Reactome: R-HSA-6781823;Reactome: R-HSA-73980;Reactome: R-HSA-6781827;Reactome: R-HSA-5617472;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-6803529;Reactome: R-HSA-167160;Reactome: R-HSA-167243;Reactome: R-HSA-72163;Reactome: R-HSA-5578749;Reactome: R-HSA-167246;Reactome: R-HSA-73780;Reactome: R-HSA-6782210;Reactome: R-HSA-167152;Reactome: R-HSA-1834949;Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-168325;Reactome: R-HSA-76061;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-6796648 "Pausing and recovery of Tat-mediated HIV elongation";"mRNA Splicing - Minor Pathway";"mRNA Capping";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA";"MicroRNA (miRNA) biogenesis";"Signaling by FGFR2 IIIa TM";"HIV Transcription Initiation";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II Transcription Elongation";"NoRC negatively regulates rRNA expression";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"FGFR2 alternative splicing";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated HIV elongation arrest and recovery";"mRNA Splicing - Major Pathway";"Transcriptional regulation by small RNAs";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Chain Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"Viral Messenger RNA Synthesis";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes" XP_037814249.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037811855.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-8873719 "Intra-Golgi traffic";"RAB geranylgeranylation" XP_037822728.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037816765.1 4 Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-72086;MetaCyc: PWY-7375 "RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"Mrna capping I" XP_037813969.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037811425.1 5 KEGG: 00240+2.4.2.3;MetaCyc: PWY-5532;Reactome: R-HSA-73621;Reactome: R-HSA-73614;KEGG: 00983+2.4.2.3 "Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine catabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes" XP_037815860.1 4 KEGG: 00030+1.1.1.49;MetaCyc: PWY-8004;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49 "Pentose phosphate pathway";"Entner-Doudoroff pathway I";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism" XP_037825425.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-1660499;Reactome: R-HSA-8873719;Reactome: R-HSA-8876198;Reactome: R-HSA-1445148 "Neutrophil degranulation";"Synthesis of PIPs at the plasma membrane";"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_037823691.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_037806425.1 22 Reactome: R-HSA-389513;Reactome: R-HSA-5339716;Reactome: R-HSA-5675221;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-4641262;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-432142;Reactome: R-HSA-5358751;Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-5673000;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-9648025;Reactome: R-HSA-6811558 "CTLA4 inhibitory signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"Negative regulation of MAPK pathway";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Platelet sensitization by LDL";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"RAF activation";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"EML4 and NUDC in mitotic spindle formation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_037826536.1 3 Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;Reactome: R-HSA-1660517 "Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane" XP_037816764.1 4 MetaCyc: PWY-7375;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-167160 "Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection" XP_037809018.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_037828795.1 2 Reactome: R-HSA-71240;KEGG: 00380+1.13.11.11 "Tryptophan catabolism";"Tryptophan metabolism" XP_037811979.1 2 Reactome: R-HSA-416482;Reactome: R-HSA-456926 "G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)" XP_037806281.1 3 MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546 "Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)" XP_037821653.1 8 Reactome: R-HSA-6798695;Reactome: R-HSA-111463;Reactome: R-HSA-8953750;Reactome: R-HSA-111459;Reactome: R-HSA-6803207;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-111464 "Neutrophil degranulation";"SMAC (DIABLO) binds to IAPs";"Transcriptional Regulation by E2F6";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Formation of apoptosome";"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes" XP_037813543.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_037809971.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037806356.1 52 Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-73779;Reactome: R-HSA-76061;Reactome: R-HSA-167172;Reactome: R-HSA-168325;Reactome: R-HSA-77075;Reactome: R-HSA-5578749;Reactome: R-HSA-167246;Reactome: R-HSA-72163;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-6782210;Reactome: R-HSA-5617472;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-6803529;Reactome: R-HSA-73980;Reactome: R-HSA-167160;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-6781823;Reactome: R-HSA-167200;Reactome: R-HSA-5601884;Reactome: R-HSA-9018519;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-72203;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-113418;Reactome: R-HSA-749476;Reactome: R-HSA-6782135;Reactome: R-HSA-203927;Reactome: R-HSA-8851708;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73776;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-72086;Reactome: R-HSA-72165 "RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Transcription of the HIV genome";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcriptional regulation by small RNAs";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Major Pathway";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"FGFR2 alternative splicing";"RNA Polymerase III Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PIWI-interacting RNA (piRNA) biogenesis";"Estrogen-dependent gene expression";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"Formation of the Early Elongation Complex";"RNA Polymerase III Abortive And Retractive Initiation";"Dual incision in TC-NER";"MicroRNA (miRNA) biogenesis";"Signaling by FGFR2 IIIa TM";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Promoter Escape";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Capping";"mRNA Splicing - Minor Pathway" XP_037823795.1 9 Reactome: R-HSA-110357;Reactome: R-HSA-110331;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-9630222;Reactome: R-HSA-9630221;Reactome: R-HSA-9608290;Reactome: R-HSA-110330;Reactome: R-HSA-9608287 "Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Defective NTHL1 substrate binding";"Defective NTHL1 substrate processing";"Defective MUTYH substrate processing";"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective MUTYH substrate binding" XP_037813508.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_037810618.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037813016.1 9 Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-75953 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation" XP_037825149.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037819955.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037820615.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037807793.1 1 Reactome: R-HSA-68962 "Activation of the pre-replicative complex" XP_037810355.1 14 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-1632852;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-5620924;Reactome: R-HSA-6811436 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Macroautophagy";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Intraflagellar transport";"COPI-independent Golgi-to-ER retrograde traffic" XP_037808606.1 3 Reactome: R-HSA-425561;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Sodium/Calcium exchangers";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_037819403.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037817470.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037828292.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037824593.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-171319 "HATs acetylate histones";"Telomere Extension By Telomerase" XP_037816244.1 5 KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-8013;MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16 "Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III";"CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism" XP_037825249.1 11 MetaCyc: PWY-6549;MetaCyc: PWY-5675;MetaCyc: PWY-381;KEGG: 00630+6.3.1.2;KEGG: 00910+6.3.1.2;Reactome: R-HSA-210455;Reactome: R-HSA-8964539;MetaCyc: PWY-6964;KEGG: 00220+6.3.1.2;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6963 "L-glutamine biosynthesis III";"Nitrate reduction V (assimilatory)";"Nitrate reduction II (assimilatory)";"Glyoxylate and dicarboxylate metabolism";"Nitrogen metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Glutamate and glutamine metabolism";"Ammonia assimilation cycle II";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I" XP_037814869.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_037811528.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706 "Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037812380.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037827001.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037807858.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037812401.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037821533.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_037812239.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689 "Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Viral mRNA Translation";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" XP_037813094.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037822290.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_037828802.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037824675.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037823740.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_037810274.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_037816650.1 3 MetaCyc: PWY-5129;KEGG: 00600+1.14.19.17;Reactome: R-HSA-1660661 "Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism";"Sphingolipid de novo biosynthesis" XP_037820340.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_037822198.1 8 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Signaling by Hippo";"PI3K-Akt signaling pathway" XP_037827686.1 5 KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527 "Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Galactose metabolism";"Stachyose degradation" XP_037818857.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_037807902.1 9 MetaCyc: PWY-6142;MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-7115;Reactome: R-HSA-1475029;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-7117 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type" XP_037805692.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037825689.1 2 MetaCyc: PWY-6558;Reactome: R-HSA-2022928 "Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis" XP_037805372.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_037817283.1 17 Reactome: R-HSA-69017;Reactome: R-HSA-176409;Reactome: R-HSA-8951664;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-174184 "CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Neddylation";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A" XP_037813182.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037810952.1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_037813998.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_037821230.1 4 MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32;KEGG: 00592+3.1.1.32 "Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism" XP_037824493.1 3 KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism" XP_037820974.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_037809022.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226 "Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037821434.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_037809355.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037812088.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037805437.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" XP_037807065.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_037825225.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037808871.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037816168.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037820545.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_037805408.1 11 Reactome: R-HSA-8847993;Reactome: R-HSA-8863795;Reactome: R-HSA-9664565;Reactome: R-HSA-6811558;Reactome: R-HSA-6785631;Reactome: R-HSA-1963642;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-1250196;Reactome: R-HSA-5673001;Reactome: R-HSA-1227986 "ERBB2 Activates PTK6 Signaling";"Downregulation of ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Regulates Cell Motility";"PI3K events in ERBB2 signaling";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC1 events in ERBB2 signaling";"RAF/MAP kinase cascade";"Signaling by ERBB2" XP_037810665.1 4 MetaCyc: PWY-7927;KEGG: 00920+2.8.1.1;MetaCyc: PWY-5350;Reactome: R-HSA-1614558 "Sulfide oxidation IV (mitochondria)";"Sulfur metabolism";"Thiosulfate disproportionation IV (rhodanese)";"Degradation of cysteine and homocysteine" XP_037825146.1 6 MetaCyc: PWY-7234;Reactome: R-HSA-73817;MetaCyc: PWY-6123;KEGG: 00230+4.1.1.21;KEGG: 00230+6.3.2.6;MetaCyc: PWY-6124 "Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II" XP_037812407.1 7 MetaCyc: PWY-6121;MetaCyc: PWY-6277;KEGG: 00230+2.4.2.14;MetaCyc: PWY-7282;MetaCyc: PWY-6122;KEGG: 00250+2.4.2.14;Reactome: R-HSA-73817 "5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis" XP_037819786.1 7 MetaCyc: PWY-6596;Reactome: R-HSA-73817;MetaCyc: PWY-7221;KEGG: 00983+1.1.1.205;Reactome: R-HSA-6798695;KEGG: 00230+1.1.1.205;MetaCyc: PWY-5695 "Adenosine nucleotides degradation I";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Neutrophil degranulation";"Purine metabolism";"Inosine 5'-phosphate degradation" XP_037821644.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557 "SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis" XP_037818341.1 2 KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019 "Pyrimidine metabolism";"Pseudouridine degradation" XP_037812225.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037825423.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-8873719;Reactome: R-HSA-1660499;Reactome: R-HSA-1445148;Reactome: R-HSA-8876198 "Neutrophil degranulation";"RAB geranylgeranylation";"Synthesis of PIPs at the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RAB GEFs exchange GTP for GDP on RABs" XP_037827043.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037825089.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037817959.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037825863.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_037827153.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597 "Hedgehog 'off' state";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (z) signalling events" XP_037812683.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_037805473.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037818806.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037805307.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_037806247.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037828007.1 11 KEGG: 04151+2.7.11.1;Reactome: R-HSA-9614657;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-163680;Reactome: R-HSA-380972;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"FOXO-mediated transcription of cell death genes";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"Relaxin signaling pathway" XP_037814792.1 13 Reactome: R-HSA-167590;Reactome: R-HSA-437239;Reactome: R-HSA-8856825;Reactome: R-HSA-5140745;Reactome: R-HSA-8866427;Reactome: R-HSA-416993;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900;Reactome: R-HSA-2132295;Reactome: R-HSA-8964038;Reactome: R-HSA-182218;Reactome: R-HSA-177504 "Nef Mediated CD4 Down-regulation";"Recycling pathway of L1";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"VLDLR internalisation and degradation";"Trafficking of GluR2-containing AMPA receptors";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"MHC class II antigen presentation";"LDL clearance";"Nef Mediated CD8 Down-regulation";"Retrograde neurotrophin signalling" XP_037822175.1 3 MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" XP_037808576.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_037817312.1 4 Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;MetaCyc: PWY-7221 "Abacavir metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis" XP_037809641.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037819047.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_037805858.1 16 Reactome: R-HSA-69017;Reactome: R-HSA-176409;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-174184 "CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A" XP_037824152.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037806376.1 4 KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;MetaCyc: PWY-7193 "Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I" XP_037827334.1 6 Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176974 "Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Unwinding of DNA" XP_037813185.1 56 Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-8854050;Reactome: R-HSA-5689603;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-69017;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-180534;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880 "Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"UCH proteinases";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Vpu mediated degradation of CD4";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of AXIN";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases" XP_037827849.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_037807722.1 3 MetaCyc: PWY-7158;MetaCyc: PWY-8099;KEGG: 00790+4.2.1.96 "L-phenylalanine degradation V";"Tetrahydropteridine recycling";"Folate biosynthesis" XP_037827851.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_037824907.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_037816638.1 58 MetaCyc: PWY-7726;KEGG: 00062+4.2.1.17+1.1.1.211;KEGG: 00280+4.2.1.17;KEGG: 00281+4.2.1.17;MetaCyc: PWY-5109;MetaCyc: PWY-6863;MetaCyc: PWY-1361;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6944;MetaCyc: PWY-7779;KEGG: 00720+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7606;MetaCyc: PWY-7656;KEGG: 00627+4.2.1.17;MetaCyc: PWY-5789;MetaCyc: PWY-7216;MetaCyc: PWY-6883;Reactome: R-HSA-77346;MetaCyc: PWY-7401;Reactome: R-HSA-77348;MetaCyc: PWY-6946;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.211;KEGG: 00362+4.2.1.17+1.1.1.35;Reactome: R-HSA-77288;MetaCyc: PWY-7654;Reactome: R-HSA-77285;KEGG: 00623+1.1.1.35;MetaCyc: PWY-6435;MetaCyc: PWY-6583;KEGG: 00650+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17;KEGG: 00930+4.2.1.17;MetaCyc: PWY-5136;Reactome: R-HSA-77305;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;MetaCyc: PWY-7094;Reactome: R-HSA-1482798;KEGG: 00362+4.2.1.17;Reactome: R-HSA-77350;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17;MetaCyc: PWY-6945;MetaCyc: PWY-7007;KEGG: 00640+4.2.1.17;KEGG: 00903+4.2.1.17;Reactome: R-HSA-77310;KEGG: 00360+4.2.1.17 "(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid elongation";"Valine, leucine and isoleucine degradation";"Geraniol degradation";"Fermentation to 2-methylbutanoate";"Pyruvate fermentation to hexanol (engineered)";"Benzoyl-coa degradation I (aerobic)";"alpha-Linolenic acid metabolism";"Androstenedione degradation";"Methyl tert-butyl ether degradation";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"beta-Alanine metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Spodoptera littoralis pheromone biosynthesis";"Aminobenzoate degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Pyruvate fermentation to butanol II (engineered)";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Caprolactam degradation";"Glutaryl-coa degradation";"Carbon fixation pathways in prokaryotes";"Fatty acid degradation";"Benzoate degradation";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Toluene degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Pyruvate fermentation to butanol I";"Butanoate metabolism";"Lysine degradation";"Geraniol degradation";"Fatty acid degradation";"Fatty acid elongation";"Lysine degradation";"Caprolactam degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Tryptophan metabolism";"2-methylpropene degradation";"Fatty acid salvage";"Acyl chain remodeling of CL";"Benzoate degradation";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Butanoate metabolism";"Tryptophan metabolism";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Methyl ketone biosynthesis (engineered)";"Propanoate metabolism";"Limonene and pinene degradation";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Phenylalanine metabolism" XP_037815945.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037805658.1 5 Reactome: R-HSA-196807;MetaCyc: PWY-5381;MetaCyc: PWY-5653;KEGG: 00760+2.7.7.18;MetaCyc: PWY-7761 "Nicotinate metabolism";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)" XP_037823153.1 17 KEGG: 00760+2.4.2.1;MetaCyc: PWY-6609;Reactome: R-HSA-74259;MetaCyc: PWY-6620;MetaCyc: PWY-6608;MetaCyc: PWY-6644;MetaCyc: PWY-5532;MetaCyc: PWY-4202;MetaCyc: PWY-7179;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6611;MetaCyc: PWY-7179-1;MetaCyc: PWY-6627;KEGG: 00230+2.4.2.1;Reactome: R-HSA-74217;MetaCyc: PWY-5695;Reactome: R-HSA-6798695 "Nicotinate and nicotinamide metabolism";"Adenine and adenosine salvage III";"Purine catabolism";"Guanine and guanosine salvage";"Guanosine nucleotides degradation III";"Fluoroacetate and fluorothreonine biosynthesis";"Nucleoside and nucleotide degradation (archaea)";"Arsenate detoxification I (mammalian)";"Purine deoxyribonucleosides degradation I";"Pyrimidine metabolism";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation II";"Salinosporamide A biosynthesis";"Purine metabolism";"Purine salvage";"Inosine 5'-phosphate degradation";"Neutrophil degranulation" XP_037822247.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_037810928.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_037812276.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037824489.1 3 Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism";"Pentose phosphate pathway" XP_037823331.1 4 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events" XP_037822164.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_037807191.1 2 Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Cargo concentration in the ER";"COPII-mediated vesicle transport" XP_037820120.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037824391.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_037809939.1 11 Reactome: R-HSA-3656253;Reactome: R-HSA-4420332;Reactome: R-HSA-3560783;Reactome: R-HSA-975634;Reactome: R-HSA-202733;Reactome: R-HSA-3656237;Reactome: R-HSA-3000170;Reactome: R-HSA-2022928;Reactome: R-HSA-2024096;Reactome: R-HSA-1971475;Reactome: R-HSA-3560801 "Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B4GALT7 causes EDS, progeroid type";"Retinoid metabolism and transport";"Cell surface interactions at the vascular wall";"Defective EXT2 causes exostoses 2";"Syndecan interactions";"HS-GAG biosynthesis";"HS-GAG degradation";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GAT3 causes JDSSDHD" XP_037808084.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_037821844.1 4 MetaCyc: PWY-7383;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8040;MetaCyc: PWY-8072 "Anaerobic energy metabolism (invertebrates, cytosol)";"D-Alanine metabolism";"Ansatrienin biosynthesis";"Alanine racemization" XP_037828702.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_037825395.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037810654.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037816699.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037806453.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037819461.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_037812464.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037810442.1 3 Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism" XP_037812734.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_037827938.1 6 Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_037822244.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_037810148.1 5 Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-73762 "Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation" XP_037806730.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037809920.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_037813713.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037806181.1 4 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_037819905.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_037820513.1 3 Reactome: R-HSA-499943;KEGG: 00240+3.5.4.12;MetaCyc: PWY-7210 "Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" XP_037827331.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037821654.1 8 Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-6803207;Reactome: R-HSA-8953750;Reactome: R-HSA-111459;Reactome: R-HSA-111464;Reactome: R-HSA-6798695;Reactome: R-HSA-111463 "Regulation of the apoptosome activity";"Formation of apoptosome";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Transcriptional Regulation by E2F6";"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Neutrophil degranulation";"SMAC (DIABLO) binds to IAPs" XP_037814360.1 52 Reactome: R-HSA-72086;Reactome: R-HSA-72165;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-76066;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-76071;Reactome: R-HSA-73776;Reactome: R-HSA-113418;Reactome: R-HSA-6782135;Reactome: R-HSA-749476;Reactome: R-HSA-167161;Reactome: R-HSA-8851708;Reactome: R-HSA-203927;Reactome: R-HSA-72203;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-73772;Reactome: R-HSA-167162;Reactome: R-HSA-6781823;Reactome: R-HSA-75953;Reactome: R-HSA-5601884;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-167160;Reactome: R-HSA-6803529;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-5617472;Reactome: R-HSA-73980;Reactome: R-HSA-167152;Reactome: R-HSA-1834949;Reactome: R-HSA-6782210;Reactome: R-HSA-73780;Reactome: R-HSA-167246;Reactome: R-HSA-5578749;Reactome: R-HSA-72163;Reactome: R-HSA-167243;Reactome: R-HSA-167172;Reactome: R-HSA-76061;Reactome: R-HSA-168325;Reactome: R-HSA-77075;Reactome: R-HSA-73779;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-73762 "mRNA Capping";"mRNA Splicing - Minor Pathway";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Promoter Escape";"Formation of the Early Elongation Complex";"Dual incision in TC-NER";"RNA Polymerase III Abortive And Retractive Initiation";"HIV Transcription Initiation";"Signaling by FGFR2 IIIa TM";"MicroRNA (miRNA) biogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation";"PIWI-interacting RNA (piRNA) biogenesis";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"FGFR2 alternative splicing";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat";"Cytosolic sensors of pathogen-associated DNA";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Chain Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Transcriptional regulation by small RNAs";"mRNA Splicing - Major Pathway";"Tat-mediated HIV elongation arrest and recovery";"Transcription of the HIV genome";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation" XP_037825861.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-5627123 "Clathrin-mediated endocytosis";"RHO GTPases activate PAKs" XP_037807696.1 6 Reactome: R-HSA-400253;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-2173788 "Circadian Clock";"Triglyceride catabolism";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"Downregulation of TGF-beta receptor signaling" XP_037813464.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "COPII-mediated vesicle transport";"Cargo concentration in the ER" XP_037818493.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037812176.1 3 KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894 "Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation" XP_037825061.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_037806631.1 8 Reactome: R-HSA-180024;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-381676;Reactome: R-HSA-442720;Reactome: R-HSA-983231 "DARPP-32 events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"PKA activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production" XP_037810889.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" XP_037807946.1 14 Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128 "Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling" XP_037815696.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_037806363.1 4 Reactome: R-HSA-2214320;Reactome: R-HSA-1650814;Reactome: R-HSA-1474228;Reactome: R-HSA-2243919 "Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes";"Degradation of the extracellular matrix";"Crosslinking of collagen fibrils" XP_037815156.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037806355.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876 "(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs" XP_037814041.1 3 Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695 "Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation" XP_037827298.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_037811253.1 14 KEGG: 00020+1.3.5.1;Reactome: R-HSA-611105;KEGG: 00720+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-7254;MetaCyc: PWY-6969;KEGG: 00650+1.3.5.1;KEGG: 00190+1.3.5.1;MetaCyc: PWY-561;Reactome: R-HSA-71403;MetaCyc: PWY-3781;MetaCyc: PWY-7279;MetaCyc: PWY-5690;MetaCyc: PWY-6728 "Citrate cycle (TCA cycle)";"Respiratory electron transport";"Carbon fixation pathways in prokaryotes";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle VII (acetate-producers)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Butanoate metabolism";"Oxidative phosphorylation";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citric acid cycle (TCA cycle)";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle" XP_037826340.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_037816708.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037805862.1 13 Reactome: R-HSA-416482;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-3928663;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3928662;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5627117 "G alpha (12/13) signalling events";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Sema4D induced cell migration and growth-cone collapse";"EPHA-mediated growth cone collapse";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"Human cytomegalovirus infection";"EPHB-mediated forward signaling";"Relaxin signaling pathway";"RHO GTPases Activate ROCKs" XP_037809981.1 5 KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-197264;Reactome: R-HSA-1368108;Reactome: R-HSA-6798695 "Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Neutrophil degranulation" XP_037811681.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_037806452.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037808015.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_037828623.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_037810713.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_037815138.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037819748.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_037817631.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_037813420.1 5 Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-6782135 "Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"Dual incision in TC-NER" XP_037828024.1 16 Reactome: R-HSA-437239;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900;Reactome: R-HSA-8866427;Reactome: R-HSA-416993;Reactome: R-HSA-3928665;Reactome: R-HSA-8964038;Reactome: R-HSA-190873;Reactome: R-HSA-196025;Reactome: R-HSA-182218;Reactome: R-HSA-5140745;Reactome: R-HSA-167590;Reactome: R-HSA-164939;Reactome: R-HSA-2132295;Reactome: R-HSA-177504 "Recycling pathway of L1";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"VLDLR internalisation and degradation";"Trafficking of GluR2-containing AMPA receptors";"EPH-ephrin mediated repulsion of cells";"LDL clearance";"Gap junction degradation";"Formation of annular gap junctions";"Nef Mediated CD8 Down-regulation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Nef Mediated CD4 Down-regulation";"Nef mediated downregulation of CD28 cell surface expression";"MHC class II antigen presentation";"Retrograde neurotrophin signalling" XP_037816074.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037817710.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_037815593.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037825408.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_037818374.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037805660.1 5 MetaCyc: PWY-7761;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5381;MetaCyc: PWY-5653;Reactome: R-HSA-196807 "NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism" XP_037824767.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_037827266.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_037805996.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_037828423.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_037816486.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_037808611.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers" XP_037825516.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_037807564.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037806772.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection" XP_037818103.1 4 MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;Reactome: R-HSA-156581;MetaCyc: PWY-5041 "2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"Methylation";"S-adenosyl-L-methionine cycle II" XP_037821837.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037820053.1 56 Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-69017;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL" XP_037805341.1 4 Reactome: R-HSA-2173788;Reactome: R-HSA-3304356;Reactome: R-HSA-3656532;Reactome: R-HSA-2173789 "Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs" XP_037805492.1 4 Reactome: R-HSA-70688;MetaCyc: PWY-6922;MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2 "Proline catabolism";"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism" XP_037825372.1 3 Reactome: R-HSA-1369062;Reactome: R-HSA-8964058;Reactome: R-HSA-9029569 "ABC transporters in lipid homeostasis";"HDL remodeling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_037818856.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_037820624.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037816182.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_037822021.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation" XP_037805266.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network" XP_037807465.1 6 Reactome: R-HSA-73817;MetaCyc: PWY-6123;KEGG: 00230+3.5.4.10+2.1.2.3;KEGG: 00670+2.1.2.3;MetaCyc: PWY-7234;MetaCyc: PWY-6124 "Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II" XP_037828446.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_037821840.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037813455.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis" XP_037805903.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_037813542.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_037808872.1 6 Reactome: R-HSA-174437;Reactome: R-HSA-110362;Reactome: R-HSA-5651801;Reactome: R-HSA-5685939;Reactome: R-HSA-162594;Reactome: R-HSA-69166 "Removal of the Flap Intermediate from the C-strand";"POLB-Dependent Long Patch Base Excision Repair";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)";"Early Phase of HIV Life Cycle";"Removal of the Flap Intermediate" XP_037816224.1 4 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes" XP_037819034.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_037817828.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_037827624.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-1268020 "Cristae formation";"Mitochondrial protein import" XP_037813676.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037811410.1 5 Reactome: R-HSA-73621;MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614 "Pyrimidine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine salvage" XP_037826102.1 5 KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-450341;Reactome: R-HSA-450321;Reactome: R-HSA-2559580 "mTOR signaling pathway";"FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence" XP_037828820.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037819718.1 14 Reactome: R-HSA-1483191;Reactome: R-HSA-4419969;MetaCyc: PWY-8053;KEGG: 00565+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8055;MetaCyc: PWY-7782;KEGG: 00564+3.1.3.4;KEGG: 00561+3.1.3.4;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8051;Reactome: R-HSA-1483213;Reactome: R-HSA-75109;MetaCyc: PWY-8052 "Synthesis of PC";"Depolymerisation of the Nuclear Lamina";"Anandamide biosynthesis II";"Ether lipid metabolism";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Sphingolipid metabolism";"Anandamide biosynthesis I";"Synthesis of PE";"Triglyceride biosynthesis";"2-arachidonoylglycerol biosynthesis" XP_037827768.1 8 Reactome: R-HSA-70268;MetaCyc: PWY-6901;KEGG: 00270+1.1.1.27;KEGG: 00010+1.1.1.27;KEGG: 00640+1.1.1.27;MetaCyc: PWY-8086;MetaCyc: PWY-5481;KEGG: 00620+1.1.1.27 "Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Cysteine and methionine metabolism";"Glycolysis / Gluconeogenesis";"Propanoate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism" XP_037807061.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_037819516.1 11 KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-450302;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-171007;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Oxidative Stress Induced Senescence";"activated TAK1 mediates p38 MAPK activation";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"p38MAPK events";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_037816369.1 5 Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-6782135 "Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"Dual incision in TC-NER" XP_037812372.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037808851.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_037809703.1 6 MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism" XP_037820829.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_037823890.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308 "Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening" XP_037811225.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037814068.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_037810312.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic" XP_037815855.1 4 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes";"T cell receptor signaling pathway" XP_037813271.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037817808.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037805686.1 7 Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852 "Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Macroautophagy" XP_037816196.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_037812046.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_037811423.1 6 KEGG: 00680+5.4.2.11;MetaCyc: PWY-8004;MetaCyc: PWY-1622;KEGG: 00260+5.4.2.11;MetaCyc: PWY-5484;KEGG: 00010+5.4.2.11 "Methane metabolism";"Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis" XP_037817463.1 13 MetaCyc: PWY-7883;Reactome: R-HSA-2022857;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52 "Anhydromuropeptides recycling II";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series" XP_037808427.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_037808340.1 2 KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921 "Histidine metabolism";"Histidine catabolism" XP_037824334.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037827382.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037828686.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037811857.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037822074.1 3 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10;Reactome: R-HSA-6783984 "One carbon pool by folate";"Glycine, serine and threonine metabolism";"Glycine degradation" XP_037819799.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_037816977.1 17 MetaCyc: PWY-7227;MetaCyc: PWY-7221;MetaCyc: PWY-7210;MetaCyc: PWY-7226;MetaCyc: PWY-7184;MetaCyc: PWY-7198;MetaCyc: PWY-7205;MetaCyc: PWY-7220;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7224;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.6;MetaCyc: PWY-6545 "Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Purine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" XP_037808925.1 4 Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_037817119.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037806304.1 4 MetaCyc: PWY-6823;MetaCyc: PWY-7887;KEGG: 00790+2.8.1.12;Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" XP_037815276.1 4 Reactome: R-HSA-6798695;Reactome: R-HSA-446203;Reactome: R-HSA-879415;Reactome: R-HSA-1799339 "Neutrophil degranulation";"Asparagine N-linked glycosylation";"Advanced glycosylation endproduct receptor signaling";"SRP-dependent cotranslational protein targeting to membrane" XP_037815451.1 13 Reactome: R-HSA-422356;Reactome: R-HSA-112043;Reactome: R-HSA-139853;Reactome: R-HSA-5218921;Reactome: R-HSA-381676;Reactome: R-HSA-2871809;Reactome: R-HSA-983695;Reactome: R-HSA-4086398;Reactome: R-HSA-1489509;Reactome: R-HSA-114508;Reactome: R-HSA-5607763;Reactome: R-HSA-2029485;Reactome: R-HSA-5578775 "Regulation of insulin secretion";"PLC beta mediated events";"Elevation of cytosolic Ca2+ levels";"VEGFR2 mediated cell proliferation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"FCERI mediated Ca+2 mobilization";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Ca2+ pathway";"DAG and IP3 signaling";"Effects of PIP2 hydrolysis";"CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis";"Ion homeostasis" XP_037811545.1 2 Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15 "Synthesis of GDP-mannose";"Starch and sucrose metabolism" XP_037806486.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_037813232.1 10 Reactome: R-HSA-399719;Reactome: R-HSA-447038;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-451308;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932;Reactome: R-HSA-442982;Reactome: R-HSA-5673001 "Trafficking of AMPA receptors";"NrCAM interactions";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Activation of Ca-permeable Kainate Receptor";"Long-term potentiation";"Synaptic adhesion-like molecules";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade" XP_037821176.1 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" XP_037813725.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037811906.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037816295.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037822176.1 6 MetaCyc: PWY-6174;Reactome: R-HSA-2426168;KEGG: 00900+2.7.1.36;MetaCyc: PWY-922;Reactome: R-HSA-191273;MetaCyc: PWY-7391 "Mevalonate pathway II (archaea)";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)" XP_037823060.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_037821669.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_037817472.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037824524.1 57 Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-6798695;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-5610783;Reactome: R-HSA-1234176;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-68949 "Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"UCH proteinases";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"Neutrophil degranulation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI2 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Orc1 removal from chromatin" XP_037817469.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037810495.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467 "Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs" XP_037827933.1 6 Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_037817343.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_037827039.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_037824681.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_037807749.1 14 Reactome: R-HSA-8943723;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593 "Regulation of PTEN mRNA translation";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity" XP_037807354.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_037824240.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_037825252.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037821135.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037815084.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" XP_037819486.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_037820116.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037827793.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037816890.1 5 Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-389357 "PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling" XP_037809040.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_037806816.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_037807419.1 4 MetaCyc: PWY-5189;KEGG: 00860+2.5.1.61;Reactome: R-HSA-189451;MetaCyc: PWY-5188 "Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)" XP_037822959.1 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" XP_037828295.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037821631.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037811314.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037820042.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_037816285.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_037806985.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037822283.1 5 Reactome: R-HSA-6798695;KEGG: 00561+2.3.1.20;Reactome: R-HSA-1482883;KEGG: 00073+2.3.1.20;Reactome: R-HSA-75109 "Neutrophil degranulation";"Glycerolipid metabolism";"Acyl chain remodeling of DAG and TAG";"Cutin, suberine and wax biosynthesis";"Triglyceride biosynthesis" XP_037806470.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection" XP_037806442.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037818733.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037812369.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037823671.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_037814695.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037813046.1 10 KEGG: 00250+2.6.1.19;MetaCyc: PWY-6535;MetaCyc: PWY-6536;KEGG: 00410+2.6.1.19;KEGG: 00640+2.6.1.19;KEGG: 00650+2.6.1.19;MetaCyc: PWY-4321;Reactome: R-HSA-916853;MetaCyc: PWY-5022;MetaCyc: PWY-6537 "Alanine, aspartate and glutamate metabolism";"4-aminobutanoate degradation I";"4-aminobutanoate degradation III";"beta-Alanine metabolism";"Propanoate metabolism";"Butanoate metabolism";"L-glutamate degradation IV";"Degradation of GABA";"4-aminobutanoate degradation V";"4-aminobutanoate degradation II" XP_037811636.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_037819851.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis" XP_037818843.1 7 KEGG: 00480+6.3.2.2;MetaCyc: PWY-6840;Reactome: R-HSA-174403;MetaCyc: PWY-7255;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.2;Reactome: R-HSA-5578999 "Glutathione metabolism";"Homoglutathione biosynthesis";"Glutathione synthesis and recycling";"Ergothioneine biosynthesis I (bacteria)";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)" XP_037822432.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_037817825.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037827283.1 4 Reactome: R-HSA-156581;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912;MetaCyc: PWY-5041 "Methylation";"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis";"S-adenosyl-L-methionine cycle II" XP_037820238.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037812204.1 11 Reactome: R-HSA-168138;KEGG: 04070+2.7.1.137;Reactome: R-HSA-109704;Reactome: R-HSA-1632852;Reactome: R-HSA-1660514;KEGG: 00562+2.7.1.137;MetaCyc: PWY-6352;Reactome: R-HSA-1660499;Reactome: R-HSA-1660516;Reactome: R-HSA-5668599;Reactome: R-HSA-1660517 "Toll Like Receptor 9 (TLR9) Cascade";"Phosphatidylinositol signaling system";"PI3K Cascade";"Macroautophagy";"Synthesis of PIPs at the Golgi membrane";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane";"RHO GTPases Activate NADPH Oxidases";"Synthesis of PIPs at the late endosome membrane" XP_037821406.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037808956.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_037823200.1 6 Reactome: R-HSA-381426;Reactome: R-HSA-5626467;Reactome: R-HSA-2173796;Reactome: R-HSA-8957275;Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"RHO GTPases activate IQGAPs";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Post-translational protein phosphorylation";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_037817939.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037809916.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_037816172.1 2 Reactome: R-HSA-195253;Reactome: R-HSA-5689896 "Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases" XP_037806154.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_037807961.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037824803.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037816445.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037805476.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_037809218.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1" XP_037825399.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037815731.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_037812062.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_037827096.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_037806651.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_037827745.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037824000.1 5 KEGG: 04070+2.7.7.41;MetaCyc: PWY-5981;KEGG: 00564+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5667 "Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis I" XP_037824618.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037817437.1 12 Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-6804756;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167200 "RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_037806918.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_037810672.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037816806.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037821692.1 12 MetaCyc: PWY-5871;MetaCyc: PWY-5872;Reactome: R-HSA-2142789;MetaCyc: PWY-5855;MetaCyc: PWY-6978;MetaCyc: PWY-5856;MetaCyc: PWY-5873;Reactome: R-HSA-1268020;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5870;MetaCyc: PWY-6708;MetaCyc: PWY-5857 "Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Mitochondrial protein import";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)" XP_037811731.1 5 Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-1362409 "Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis" XP_037817172.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_037809320.1 4 Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "ECM proteoglycans";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_037818291.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_037821778.1 1 Reactome: R-HSA-5689896 "Ovarian tumor domain proteases" XP_037808582.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037808808.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037827111.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_037812274.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037810054.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037824600.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037821074.1 3 Reactome: R-HSA-8856828;Reactome: R-HSA-8875656;Reactome: R-HSA-8854214 "Clathrin-mediated endocytosis";"MET receptor recycling";"TBC/RABGAPs" XP_037810001.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-1799339 "Viral mRNA Translation";"Peptide chain elongation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane" XP_037806312.1 4 Reactome: R-HSA-2214320;Reactome: R-HSA-2243919;Reactome: R-HSA-1474228;Reactome: R-HSA-1650814 "Anchoring fibril formation";"Crosslinking of collagen fibrils";"Degradation of the extracellular matrix";"Collagen biosynthesis and modifying enzymes" XP_037823015.1 5 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_037827070.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037821589.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037819968.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037814545.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037823528.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295 "Kinesins";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_037813649.1 10 Reactome: R-HSA-2514853;Reactome: R-HSA-6814122;Reactome: R-HSA-8939243;Reactome: R-HSA-6798695;Reactome: R-HSA-1483191;Reactome: R-HSA-8934903;Reactome: R-HSA-201688;Reactome: R-HSA-445144;Reactome: R-HSA-6804756;Reactome: R-HSA-8948751 "Condensation of Prometaphase Chromosomes";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Neutrophil degranulation";"Synthesis of PC";"Receptor Mediated Mitophagy";"WNT mediated activation of DVL";"Signal transduction by L1";"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity" XP_037814536.1 14 KEGG: 00670+2.1.2.1;MetaCyc: PWY-181;MetaCyc: PWY-3661;KEGG: 00630+2.1.2.1;MetaCyc: PWY-3841;MetaCyc: PWY-3661-1;KEGG: 00680+2.1.2.1;KEGG: 00460+2.1.2.1;Reactome: R-HSA-196757;MetaCyc: PWY-2161;MetaCyc: PWY-5497;MetaCyc: PWY-1622;MetaCyc: PWY-2201;KEGG: 00260+2.1.2.1 "One carbon pool by folate";"Photorespiration ";"Glycine betaine degradation I";"Glyoxylate and dicarboxylate metabolism";"Folate transformations II (plants)";"Glycine betaine degradation II (mammalian)";"Methane metabolism";"Cyanoamino acid metabolism";"Metabolism of folate and pterines";"Folate polyglutamylation";"Purine nucleobases degradation II (anaerobic)";"Formaldehyde assimilation I (serine pathway)";"Folate transformations I";"Glycine, serine and threonine metabolism" XP_037812942.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_037822899.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823 "DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex" XP_037811551.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_037810700.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_037810158.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_037818572.1 56 Reactome: R-HSA-5610783;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-68949;Reactome: R-HSA-174178;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5689603;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761 "Degradation of GLI2 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Orc1 removal from chromatin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"UCH proteinases";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling" XP_037828608.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037806412.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037823254.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037823417.1 9 Reactome: R-HSA-6798695;Reactome: R-HSA-5674135;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-166208 "Neutrophil degranulation";"MAP2K and MAPK activation";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Macroautophagy";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling" XP_037823789.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_037813096.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037819783.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_037819904.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-168138 "Factors involved in megakaryocyte development and platelet production";"Toll Like Receptor 9 (TLR9) Cascade" XP_037816813.1 7 MetaCyc: PWY-6737;Reactome: R-HSA-70221;MetaCyc: PWY-6724;KEGG: 00500+2.4.1.25;MetaCyc: PWY-5941;Reactome: R-HSA-6798695;MetaCyc: PWY-7238 "Starch degradation V";"Glycogen breakdown (glycogenolysis)";"Starch degradation II";"Starch and sucrose metabolism";"Glycogen degradation II";"Neutrophil degranulation";"Sucrose biosynthesis II" XP_037821232.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_037806291.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037820785.1 3 MetaCyc: PWY-7285;MetaCyc: PWY-6829;MetaCyc: PWY-7286 "Methylwyosine biosynthesis";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis" XP_037806778.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection" XP_037824116.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" XP_037810702.1 2 KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23 "Drug metabolism - other enzymes";"Pyrimidine metabolism" XP_037825402.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_037814878.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_037823934.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037823445.1 1 Reactome: R-HSA-428643 "Organic anion transporters" XP_037827205.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_037810679.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037826310.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037813867.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_037816944.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037812559.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_037805366.1 1 Reactome: R-HSA-200425 "Carnitine metabolism" XP_037806799.1 4 MetaCyc: PWY-6281;Reactome: R-HSA-2408557;KEGG: 00450+2.9.1.2;KEGG: 00970+2.9.1.2 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis";"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis" XP_037824173.1 8 KEGG: 00190+7.1.2.2;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;KEGG: 00195+7.1.2.2;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;MetaCyc: PWY-7980 "Oxidative phosphorylation";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Photosynthesis";"Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ATP biosynthesis" XP_037815935.1 2 Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" XP_037820117.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037813091.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037815746.1 2 Reactome: R-HSA-5362517;Reactome: R-HSA-204174 "Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_037808569.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_037816065.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037822889.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037818964.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_037822732.1 56 Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-2871837;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-174154;Reactome: R-HSA-5689603;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-5610783;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-68949 "Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"FCERI mediated NF-kB activation";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"APC/C:Cdc20 mediated degradation of Securin";"UCH proteinases";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI2 by the proteasome";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Orc1 removal from chromatin" XP_037810570.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037813896.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_037826960.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_037814578.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_037811735.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037827386.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_037824305.1 1 Reactome: R-HSA-6785631 "ERBB2 Regulates Cell Motility" XP_037823735.1 1 KEGG: 00230+3.6.1.29 "Purine metabolism" XP_037818813.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_037815226.1 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" XP_037820512.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037812069.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_037817513.1 7 Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-8950505;Reactome: R-HSA-389960 "Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Formation of tubulin folding intermediates by CCT/TriC" XP_037823673.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_037823045.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_037808953.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037818096.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037822974.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037809518.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037818999.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037808249.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_037812033.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_037818300.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_037822326.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_037824237.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_037821829.1 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" XP_037824664.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037812818.1 1 Reactome: R-HSA-203754 "NOSIP mediated eNOS trafficking" XP_037815232.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_037823446.1 1 Reactome: R-HSA-428643 "Organic anion transporters" XP_037825261.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_037809098.1 3 Reactome: R-HSA-8963684;Reactome: R-HSA-204174;Reactome: R-HSA-156590 "Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation" XP_037812941.1 16 MetaCyc: PWY-5538;MetaCyc: PWY-6728;MetaCyc: PWY-5749;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.4;Reactome: R-HSA-71403;MetaCyc: PWY-5392;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.4;MetaCyc: PWY-5913;KEGG: 00020+6.2.1.5;KEGG: 00660+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-7384;MetaCyc: PWY-6969 "Pyruvate fermentation to acetate VI";"Methylaspartate cycle";"Itaconate degradation";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" XP_037812781.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_037822394.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_037817950.1 4 Reactome: R-HSA-4719377;Reactome: R-HSA-4719360;Reactome: R-HSA-162699;Reactome: R-HSA-4717374 "Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM1 causes DPM1-CDG (CDG-1e)" XP_037823260.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037815512.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037825720.1 5 Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14 "Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism" XP_037806295.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037822768.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037809617.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037817712.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037809361.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037818255.1 1 Reactome: R-HSA-2514859 "Inactivation, recovery and regulation of the phototransduction cascade" XP_037824147.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037810196.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037809990.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;Reactome: R-HSA-197264;MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21 "Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism" XP_037807479.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_037813086.1 31 MetaCyc: PWY-5367;MetaCyc: PWY-7723;Reactome: R-HSA-199220;MetaCyc: PWY-5147;MetaCyc: PWY-5142;MetaCyc: PWY-6519;MetaCyc: PWY-7664;MetaCyc: PWY-5366;MetaCyc: PWY-4381;MetaCyc: PWY-8012;MetaCyc: PWY-6799;MetaCyc: PWY-5971;MetaCyc: PWY-7388;MetaCyc: PWY-5966-1;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8047;Reactome: R-HSA-75105;MetaCyc: PWYG-321;Reactome: R-HSA-2426168;MetaCyc: PWY-5989;MetaCyc: PWY-6282;MetaCyc: PWY-8049;MetaCyc: PWY-5994;MetaCyc: PWY-7746;Reactome: R-HSA-163765;MetaCyc: PWY-7663;MetaCyc: PWY-7858;MetaCyc: PWY-5973;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6113;Reactome: R-HSA-9029558 "Petroselinate biosynthesis";"Bacterial bioluminescence";"Vitamin B5 (pantothenate) metabolism";"Oleate biosynthesis I (plants)";"Acyl-[acyl-carrier protein] thioesterase pathway";"8-amino-7-oxononanoate biosynthesis I";"Oleate biosynthesis IV (anaerobic)";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Mupirocin biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Biotin metabolism";"Bryostatin biosynthesis";"Fatty acyl-CoA biosynthesis";"";"Activation of gene expression by SREBF (SREBP)";"Stearate biosynthesis II (bacteria and plants)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Pederin biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Mycobacterial sulfolipid biosynthesis";"ChREBP activates metabolic gene expression";"Gondoate biosynthesis (anaerobic)";"(5Z)-dodecenoate biosynthesis II";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis";"Superpathway of mycolate biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis" XP_037813422.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037826485.1 7 Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-156711 "Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events" XP_037814894.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_037816228.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_037814951.1 7 KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway" XP_037819604.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_037826779.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_037816124.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_037825276.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I" XP_037806895.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection" XP_037822503.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037826463.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037806137.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_037814960.1 5 Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5610787 "Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Hedgehog 'off' state" XP_037811807.1 12 MetaCyc: PWY-7230;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5856;MetaCyc: PWY-5872;MetaCyc: PWY-5871;MetaCyc: PWY-5855;Reactome: R-HSA-2142789;MetaCyc: PWY-7233;MetaCyc: PWY-5870;MetaCyc: PWY-6708;MetaCyc: PWY-5857;MetaCyc: PWY-5873 "Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)" XP_037822923.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037812373.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037824766.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_037827100.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_037820389.1 5 MetaCyc: PWY-7922;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis" XP_037810352.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037826568.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037814383.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037821581.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" XP_037825307.1 5 Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-430039;Reactome: R-HSA-450513;Reactome: R-HSA-450604 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA" XP_037812051.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_037824755.1 4 Reactome: R-HSA-3359463;Reactome: R-HSA-196741;Reactome: R-HSA-3359462;Reactome: R-HSA-8964011 "Defective CUBN causes hereditary megaloblastic anemia 1";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective AMN causes hereditary megaloblastic anemia 1";"HDL clearance" XP_037814121.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037819273.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_037825448.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037822425.1 6 MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_037809631.1 22 Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-5675221;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-389513;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-6811558;Reactome: R-HSA-9648025;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-432142;Reactome: R-HSA-5358751 "Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Negative regulation of MAPK pathway";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"EML4 and NUDC in mitotic spindle formation";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"RAF activation";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Platelet sensitization by LDL";"S45 mutants of beta-catenin aren't phosphorylated" XP_037822590.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_037823349.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037808862.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037821310.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037821325.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_037825475.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037819456.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_037820906.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037823147.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_037816755.1 11 MetaCyc: PWY-7790;MetaCyc: PWY-5686;Reactome: R-HSA-500753;KEGG: 00240+3.5.2.3;KEGG: 00250+2.1.3.2;MetaCyc: PWY-7400;KEGG: 00240+6.3.5.5;KEGG: 00250+6.3.5.5;MetaCyc: PWY-7791;MetaCyc: PWY-5154;KEGG: 00240+2.1.3.2 "UMP biosynthesis II";"UMP biosynthesis I";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis III";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine metabolism" XP_037806121.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_037816212.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_037827364.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037817780.1 8 Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;MetaCyc: PWY-7980;Reactome: R-HSA-1222556;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-917977 "Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ATP biosynthesis";"ROS and RNS production in phagocytes";"Oxidative phosphorylation";"Photosynthesis";"Transferrin endocytosis and recycling" XP_037818134.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_037812513.1 1 MetaCyc: PWY-6938 "NADH repair" XP_037809619.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037810676.1 3 Reactome: R-HSA-5358565;Reactome: R-HSA-5632968;Reactome: R-HSA-5632928 "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2" XP_037807704.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_037816610.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037827135.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037816908.1 8 MetaCyc: PWY-7980;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;KEGG: 00195+7.1.2.2;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;KEGG: 00190+7.1.2.2 "ATP biosynthesis";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Photosynthesis";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Oxidative phosphorylation" XP_037806988.1 3 Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097 "Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway" XP_037825945.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_037828315.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037807537.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037821139.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_037805243.1 5 KEGG: 00020+4.1.1.32;KEGG: 00010+4.1.1.32;KEGG: 00620+4.1.1.32;Reactome: R-HSA-70263;MetaCyc: PWY-7383 "Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_037815088.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_037819284.1 22 MetaCyc: PWY-7592;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7606;MetaCyc: PWY-7053;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7727;MetaCyc: PWY-5080;MetaCyc: PWY-5353;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7726;MetaCyc: PWY-7728;Reactome: R-HSA-75876;MetaCyc: PWY-6958;MetaCyc: PWY-7049;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7601 "Arachidonate biosynthesis III (6-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_037825223.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037817262.1 9 KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-416476;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367 "Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism" XP_037816921.1 5 Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604 "Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling" XP_037806382.1 8 KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1 "Glycolysis / Gluconeogenesis";"Glycolysis";"Streptomycin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Fructose and mannose metabolism";"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis" XP_037820651.1 7 KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis" XP_037810051.1 3 Reactome: R-HSA-114608;Reactome: R-HSA-194313;Reactome: R-HSA-195399 "Platelet degranulation";"VEGF ligand-receptor interactions";"VEGF binds to VEGFR leading to receptor dimerization" XP_037815183.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037826582.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037805616.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037811030.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037812516.1 30 Reactome: R-HSA-5684264;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-2122947;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-2894862;Reactome: R-HSA-5610785;Reactome: R-HSA-2644606;Reactome: R-HSA-187577;Reactome: R-HSA-2565942;Reactome: R-HSA-5610783;Reactome: R-HSA-917937;Reactome: R-HSA-69231;Reactome: R-HSA-1170546;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-400253;Reactome: R-HSA-5607764;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-2644607;Reactome: R-HSA-174113;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-195253 "MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"NOTCH1 Intracellular Domain Regulates Transcription";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"GLI3 is processed to GLI3R by the proteasome";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of PLK1 Activity at G2/M Transition";"Degradation of GLI2 by the proteasome";"Iron uptake and transport";"Cyclin D associated events in G1";"Prolactin receptor signaling";"Downstream TCR signaling";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"Circadian Clock";"CLEC7A (Dectin-1) signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex" XP_037814278.1 8 Reactome: R-HSA-6798695;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;MetaCyc: PWY-7179;MetaCyc: PWY-6611;KEGG: 00230+3.5.4.4;Reactome: R-HSA-5683826;MetaCyc: PWY-6609 "Neutrophil degranulation";"Purine salvage";"Purine deoxyribonucleosides degradation II";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage V";"Purine metabolism";"Surfactant metabolism";"Adenine and adenosine salvage III" XP_037809339.1 4 Reactome: R-HSA-6798695;Reactome: R-HSA-499943;Reactome: R-HSA-2162123;KEGG: 00590+5.3.99.3 "Neutrophil degranulation";"Interconversion of nucleotide di- and triphosphates";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Arachidonic acid metabolism" XP_037809001.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_037827830.1 6 Reactome: R-HSA-71336;MetaCyc: PWY-5723;KEGG: 00040+5.1.3.1;KEGG: 00710+5.1.3.1;KEGG: 00030+5.1.3.1;MetaCyc: PWY-1861 "Pentose phosphate pathway";"Rubisco shunt";"Pentose and glucuronate interconversions";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" XP_037807208.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706 "Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037807781.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037828260.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_037811350.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037822457.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_037813142.1 4 Reactome: R-HSA-1632852;Reactome: R-HSA-936440;Reactome: R-HSA-8934903;Reactome: R-HSA-5205685 "Macroautophagy";"Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy";"Pink/Parkin Mediated Mitophagy" XP_037816249.1 5 KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I" XP_037824229.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_037821009.1 7 Reactome: R-HSA-1268020;KEGG: 00190+7.1.2.2;Reactome: R-HSA-2151201;Reactome: R-HSA-163210;Reactome: R-HSA-8949613;MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2 "Mitochondrial protein import";"Oxidative phosphorylation";"Transcriptional activation of mitochondrial biogenesis";"Formation of ATP by chemiosmotic coupling";"Cristae formation";"ATP biosynthesis";"Photosynthesis" XP_037824586.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_037820138.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_037816160.1 14 MetaCyc: PWY-8051;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;KEGG: 00564+2.3.1.15;Reactome: R-HSA-2426168;Reactome: R-HSA-75109;MetaCyc: PWY-8053;MetaCyc: PWY-7411;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;Reactome: R-HSA-8931987;MetaCyc: PWY-6453;Reactome: R-HSA-9018519;MetaCyc: PWY-8055 "Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Activation of gene expression by SREBF (SREBP)";"Triglyceride biosynthesis";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"RUNX1 regulates estrogen receptor mediated transcription";"Stigma estolide biosynthesis";"Estrogen-dependent gene expression";"Palmitoyl ethanolamide biosynthesis" XP_037807549.1 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" XP_037815738.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037821757.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037808643.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037811919.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037817920.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_037820628.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037805264.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037810116.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037827104.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037816421.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037806396.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037821144.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_037820652.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection" XP_037818840.1 7 KEGG: 00480+6.3.2.2;MetaCyc: PWY-6840;MetaCyc: PWY-7255;Reactome: R-HSA-174403;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.2;Reactome: R-HSA-5578999 "Glutathione metabolism";"Homoglutathione biosynthesis";"Ergothioneine biosynthesis I (bacteria)";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)" XP_037823198.1 6 Reactome: R-HSA-2173796;Reactome: R-HSA-8957275;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-5626467;Reactome: R-HSA-381426 "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Post-translational protein phosphorylation";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"RHO GTPases activate IQGAPs";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_037825005.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037828610.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_037812075.1 19 MetaCyc: PWY-7227;MetaCyc: PWY-7221;MetaCyc: PWY-7210;MetaCyc: PWY-7226;MetaCyc: PWY-7198;MetaCyc: PWY-7184;MetaCyc: PWY-7205;MetaCyc: PWY-7220;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7224;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7197;MetaCyc: PWY-7187;Reactome: R-HSA-380320;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.6;MetaCyc: PWY-6545;Reactome: R-HSA-380270 "Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Purine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Recruitment of NuMA to mitotic centrosomes";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Recruitment of mitotic centrosome proteins and complexes" XP_037809332.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037813478.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_037810692.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_037822898.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_037808769.1 3 KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403;MetaCyc: PWY-7942 "Glutathione metabolism";"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism" XP_037815141.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_037817274.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037824344.1 7 KEGG: 00230+3.5.4.4;Reactome: R-HSA-6798695;MetaCyc: PWY-6611;MetaCyc: PWY-7179;MetaCyc: PWY-6609;MetaCyc: PWY-7179-1;Reactome: R-HSA-5683826 "Purine metabolism";"Neutrophil degranulation";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II";"Surfactant metabolism" XP_037824626.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_037810322.1 12 Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878 "HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"COPI-mediated anterograde transport" XP_037813233.1 10 Reactome: R-HSA-451308;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-447038;Reactome: R-HSA-399719 "Activation of Ca-permeable Kainate Receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Long-term potentiation";"Synaptic adhesion-like molecules";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"NrCAM interactions";"Trafficking of AMPA receptors" XP_037809477.1 3 KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217 "Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage" XP_037806784.1 7 KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis" XP_037811621.1 5 Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-109704;Reactome: R-HSA-1257604 "RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K Cascade";"PIP3 activates AKT signaling" XP_037815286.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037806607.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037812130.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037818968.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_037810947.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975957 "Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Viral mRNA Translation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_037817339.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_037825358.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037826513.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037822536.1 12 MetaCyc: PWY-7230;MetaCyc: PWY-5856;MetaCyc: PWY-5872;MetaCyc: PWY-5871;MetaCyc: PWY-5855;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-7233;Reactome: R-HSA-2142789;MetaCyc: PWY-5870;MetaCyc: PWY-6708;MetaCyc: PWY-5857;MetaCyc: PWY-5873 "Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)" XP_037819946.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947 "HDACs deacetylate histones";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" XP_037821529.1 3 Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-8939243 "Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_037810694.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_037817849.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037811303.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037823203.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_037813106.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037809910.1 7 Reactome: R-HSA-446193;MetaCyc: PWY-5265;KEGG: 00510+2.7.8.15;KEGG: 00550+2.7.8.13;MetaCyc: PWY-6470;Reactome: R-HSA-4549356;MetaCyc: PWY-6471 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis II (staphylococci)";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis IV (Enterococcus faecium)" XP_037817095.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037806863.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection" XP_037818547.1 4 Reactome: R-HSA-8874211;Reactome: R-HSA-8963889;Reactome: R-HSA-381033;Reactome: R-HSA-1655829 "CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_037819580.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_037821830.1 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" XP_037815187.1 1 Reactome: R-HSA-5683826 "Surfactant metabolism" XP_037820453.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_037808223.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037811783.1 10 MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-5826;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-4061 "4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I" XP_037812371.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037810224.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_037808296.1 3 Reactome: R-HSA-9609523;Reactome: R-HSA-1236974;Reactome: R-HSA-1799339 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane" XP_037819695.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037817677.1 4 Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090 "Collagen degradation";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures" XP_037823821.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037817298.1 4 Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437 "UCH proteinases";"HATs acetylate histones";"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation" XP_037827074.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037806085.1 4 Reactome: R-HSA-8866427;MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-9031525 "VLDLR internalisation and degradation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake" XP_037811413.1 5 KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614;Reactome: R-HSA-73621;KEGG: 00240+2.4.2.3;MetaCyc: PWY-5532 "Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine catabolism";"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)" XP_037817102.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037813132.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_037813234.1 10 Reactome: R-HSA-447038;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-451308;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932;Reactome: R-HSA-442982 "NrCAM interactions";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Activation of Ca-permeable Kainate Receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Long-term potentiation";"Synaptic adhesion-like molecules";"Ras activation upon Ca2+ influx through NMDA receptor" XP_037805818.1 2 Reactome: R-HSA-500753;Reactome: R-HSA-73621 "Pyrimidine biosynthesis";"Pyrimidine catabolism" XP_037808264.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_037808580.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_037808584.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037814861.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_037823645.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037820667.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_037808644.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037811758.1 13 KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2024101 "Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"CS/DS degradation" XP_037825396.1 18 MetaCyc: PWY-5084;KEGG: 00260+1.8.1.4;KEGG: 00640+1.8.1.4;KEGG: 00310+1.8.1.4;KEGG: 00020+1.8.1.4;KEGG: 00280+1.8.1.4;KEGG: 00380+1.8.1.4;Reactome: R-HSA-70895;Reactome: R-HSA-71403;Reactome: R-HSA-389661;Reactome: R-HSA-5362517;MetaCyc: PWY-5046;Reactome: R-HSA-71064;KEGG: 00620+1.8.1.4;Reactome: R-HSA-70268;KEGG: 00010+1.8.1.4;Reactome: R-HSA-204174;Reactome: R-HSA-6783984 "2-oxoglutarate decarboxylation to succinyl-CoA";"Glycine, serine and threonine metabolism";"Propanoate metabolism";"Lysine degradation";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine degradation";"Tryptophan metabolism";"Branched-chain amino acid catabolism";"Citric acid cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Lysine catabolism";"Pyruvate metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycine degradation" XP_037808964.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037821298.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_037812208.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037810518.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-6783984 "Glyoxylate metabolism and glycine degradation";"Glycine degradation" XP_037812759.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037807596.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037813200.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1" XP_037818125.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037819108.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037806117.1 14 KEGG: 00190+1.3.5.1;MetaCyc: PWY-7279;MetaCyc: PWY-3781;MetaCyc: PWY-561;Reactome: R-HSA-71403;MetaCyc: PWY-4302;MetaCyc: PWY-7254;Reactome: R-HSA-611105;KEGG: 00020+1.3.5.1;KEGG: 00720+1.3.5.1;KEGG: 00650+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-5690 "Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citric acid cycle (TCA cycle)";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle VII (acetate-producers)";"Respiratory electron transport";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Butanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"TCA cycle II (plants and fungi)" XP_037817341.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_037826730.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_037821868.1 2 Reactome: R-HSA-162588;Reactome: R-HSA-917729 "Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_037806986.1 3 Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097 "Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway" XP_037807800.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037822871.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037812623.1 6 MetaCyc: PWY-7356;MetaCyc: PWY-6907;Reactome: R-HSA-196819;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6908;MetaCyc: PWY-6898 "Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Vitamin B1 (thiamin) metabolism";"Thiamine metabolism";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine salvage III" XP_037824986.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_037807627.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_037812989.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037824118.1 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" XP_037813825.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037825059.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling" XP_037828771.1 3 KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282;Reactome: R-HSA-2024096 "Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B";"HS-GAG degradation" XP_037828010.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-171319 "HATs acetylate histones";"Telomere Extension By Telomerase" XP_037817333.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_037816040.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037820710.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway" XP_037818863.1 4 Reactome: R-HSA-112043;Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-418594 "PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"G alpha (i) signalling events" XP_037805776.1 11 Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167152 "Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat" XP_037812346.1 2 Reactome: R-HSA-977606;Reactome: R-HSA-166665 "Regulation of Complement cascade";"Terminal pathway of complement" XP_037806343.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7619;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199 "(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation" XP_037810845.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_037828819.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037826501.1 2 KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" XP_037814099.1 26 Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472;Reactome: R-HSA-3214847;Reactome: R-HSA-933541;Reactome: R-HSA-9617629;Reactome: R-HSA-381340;Reactome: R-HSA-8941856;Reactome: R-HSA-9013508;Reactome: R-HSA-9614657;Reactome: R-HSA-918233;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-3134973;Reactome: R-HSA-3371568;Reactome: R-HSA-1912408;Reactome: R-HSA-5621575;Reactome: R-HSA-1234158;Reactome: R-HSA-400253;Reactome: R-HSA-201722;Reactome: R-HSA-3899300;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-9018519;Reactome: R-HSA-8866907 "RORA activates gene expression";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HATs acetylate histones";"TRAF6 mediated IRF7 activation";"Regulation of FOXO transcriptional activity by acetylation";"Transcriptional regulation of white adipocyte differentiation";"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"FOXO-mediated transcription of cell death genes";"TRAF3-dependent IRF activation pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Attenuation phase";"Pre-NOTCH Transcription and Translation";"CD209 (DC-SIGN) signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"Circadian Clock";"Formation of the beta-catenin:TCF transactivating complex";"SUMOylation of transcription cofactors";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_037813645.1 10 Reactome: R-HSA-6814122;Reactome: R-HSA-2514853;Reactome: R-HSA-8948751;Reactome: R-HSA-6804756;Reactome: R-HSA-445144;Reactome: R-HSA-201688;Reactome: R-HSA-8934903;Reactome: R-HSA-6798695;Reactome: R-HSA-1483191;Reactome: R-HSA-8939243 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Condensation of Prometaphase Chromosomes";"Regulation of PTEN stability and activity";"Regulation of TP53 Activity through Phosphorylation";"Signal transduction by L1";"WNT mediated activation of DVL";"Receptor Mediated Mitophagy";"Neutrophil degranulation";"Synthesis of PC";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_037822967.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" XP_037825913.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_037809447.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037806777.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" XP_037807278.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037809069.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_037816985.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" XP_037819075.1 2 Reactome: R-HSA-6802953;Reactome: R-HSA-5658442 "RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs" XP_037817277.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037813614.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_037817743.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_037806118.1 14 MetaCyc: PWY-6969;KEGG: 00650+1.3.5.1;MetaCyc: PWY-7254;MetaCyc: PWY-4302;KEGG: 00020+1.3.5.1;KEGG: 00720+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-3781;MetaCyc: PWY-7279;Reactome: R-HSA-71403;MetaCyc: PWY-561;KEGG: 00190+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-6728 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Butanoate metabolism";"TCA cycle VII (acetate-producers)";"Aerobic respiration III (alternative oxidase pathway)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Respiratory electron transport";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Citric acid cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Oxidative phosphorylation";"TCA cycle II (plants and fungi)";"Methylaspartate cycle" XP_037806166.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_037806152.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037827740.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037818924.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_037812194.1 18 MetaCyc: PWY-7417;Reactome: R-HSA-1482801;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-1483166;MetaCyc: PWY-7409;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922 "Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PS";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Acyl chain remodelling of PC";"Synthesis of PA";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI" XP_037826758.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_037817221.1 9 KEGG: 00620+6.4.1.1;Reactome: R-HSA-3371599;KEGG: 00020+6.4.1.1;KEGG: 00720+6.4.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-8086;Reactome: R-HSA-196780;MetaCyc: PWY-6146;MetaCyc: PWY-6142 "Pyruvate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Biotin transport and metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_037809589.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-6798695;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation";"COPI-mediated anterograde transport" XP_037825607.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037815002.1 4 MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism" XP_037809945.1 19 KEGG: 00640+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7606;MetaCyc: PWY-7338;MetaCyc: PWY-7574;MetaCyc: PWY-7854;MetaCyc: PWY-7007;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7726;MetaCyc: PWY-7340;MetaCyc: PWY-7337;MetaCyc: PWY-735;MetaCyc: PWY-6837;MetaCyc: PWY-5136;MetaCyc: PWY-6920;MetaCyc: PWY-7288;KEGG: 00592+1.3.3.6;KEGG: 00071+1.3.3.6 "Propanoate metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoyl-coa degradation II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"beta-Alanine metabolism";"(5Z)-dodecenoate biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation II (plant peroxisome)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"alpha-Linolenic acid metabolism";"Fatty acid degradation" XP_037806849.1 7 KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis" XP_037811420.1 6 KEGG: 00680+5.4.2.11;MetaCyc: PWY-8004;KEGG: 00260+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-5484;KEGG: 00010+5.4.2.11 "Methane metabolism";"Entner-Doudoroff pathway I";"Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis" XP_037826656.1 12 MetaCyc: PWY-6932;KEGG: 00261+2.7.7.4;Reactome: R-HSA-2408550;MetaCyc: PWY-5340;KEGG: 00230+2.7.1.25;KEGG: 00230+2.7.7.4;KEGG: 00920+2.7.7.4;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5278;Reactome: R-HSA-174362;KEGG: 00450+2.7.7.4;MetaCyc: PWY-6683 "Selenate reduction";"Monobactam biosynthesis";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfate activation for sulfonation";"Purine metabolism";"Purine metabolism";"Sulfur metabolism";"Sulfur metabolism";"Sulfite oxidation III";"Transport and synthesis of PAPS";"Selenocompound metabolism";"Assimilatory sulfate reduction III" XP_037828089.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_037825428.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037807187.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037823058.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_037808556.1 7 Reactome: R-HSA-2122948;MetaCyc: PWY-7511;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606 "Activated NOTCH1 Transmits Signal to the Nucleus";"Protein ubiquitination";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_037818326.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_037820769.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037822893.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037828290.1 2 KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_037824504.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037817154.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_037827791.1 42 Reactome: R-HSA-110331;Reactome: R-HSA-1221632;Reactome: R-HSA-606279;Reactome: R-HSA-73728;Reactome: R-HSA-69473;Reactome: R-HSA-5250924;Reactome: R-HSA-5625886;Reactome: R-HSA-5693565;Reactome: R-HSA-73772;Reactome: R-HSA-110328;Reactome: R-HSA-9609690;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-201722;Reactome: R-HSA-4551638;Reactome: R-HSA-8939236;Reactome: R-HSA-212300;Reactome: R-HSA-427413;Reactome: R-HSA-9018519;Reactome: R-HSA-427359;Reactome: R-HSA-9616222;Reactome: R-HSA-3214847;Reactome: R-HSA-5617472;Reactome: R-HSA-912446;Reactome: R-HSA-3214858;Reactome: R-HSA-5578749;Reactome: R-HSA-977225;Reactome: R-HSA-110330;Reactome: R-HSA-3214841;Reactome: R-HSA-1912408;Reactome: R-HSA-2559582;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-2299718;Reactome: R-HSA-3214842;Reactome: R-HSA-110329;Reactome: R-HSA-8936459;Reactome: R-HSA-2559586;Reactome: R-HSA-2559580;Reactome: R-HSA-5334118;Reactome: R-HSA-171306;Reactome: R-HSA-9610379 "Cleavage of the damaged purine";"Meiotic synapsis";"Deposition of new CENPA-containing nucleosomes at the centromere";"RNA Polymerase I Promoter Opening";"G2/M DNA damage checkpoint";"B-WICH complex positively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RNA Polymerase I Promoter Escape";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HCMV Early Events";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"Formation of the beta-catenin:TCF transactivating complex";"SUMOylation of chromatin organization proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression";"Estrogen-dependent gene expression";"SIRT1 negatively regulates rRNA expression";"Transcriptional regulation of granulopoiesis";"HATs acetylate histones";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Meiotic recombination";"RMTs methylate histone arginines";"Transcriptional regulation by small RNAs";"Amyloid fiber formation";"Recognition and association of DNA glycosylase with site containing an affected purine";"PKMTs methylate histone lysines";"Pre-NOTCH Transcription and Translation";"Senescence-Associated Secretory Phenotype (SASP)";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Condensation of Prophase Chromosomes";"HDMs demethylate histones";"Cleavage of the damaged pyrimidine";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"DNA Damage/Telomere Stress Induced Senescence";"Oxidative Stress Induced Senescence";"DNA methylation";"Packaging Of Telomere Ends";"HCMV Late Events" XP_037810780.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037824968.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_037812919.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037805316.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037810450.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_037822807.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037811044.1 7 Reactome: R-HSA-389960;Reactome: R-HSA-6798695;Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-6814122 "Formation of tubulin folding intermediates by CCT/TriC";"Neutrophil degranulation";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_037808553.1 13 KEGG: 00020+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5913;MetaCyc: PWY-6728;MetaCyc: PWY-5538;MetaCyc: PWY-6969;KEGG: 00640+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-5392;Reactome: R-HSA-71403;MetaCyc: PWY-5537;KEGG: 00720+6.2.1.5 "Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes" XP_037813502.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037828301.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037825472.1 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" XP_037824920.1 8 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Thermogenesis" XP_037808686.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037825079.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259 "Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism" XP_037818634.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation" XP_037824047.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037806998.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_037820818.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037818345.1 18 Reactome: R-HSA-1483166;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-7783;Reactome: R-HSA-1482922;MetaCyc: PWY-7416;Reactome: R-HSA-1482801;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482925;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-8051 "Synthesis of PA";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Plasmalogen degradation";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Glycerophospholipid metabolism";"Acyl chain remodelling of PG";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Acyl chain remodelling of PC";"Anandamide biosynthesis I" XP_037826151.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_037820631.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037805516.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_037806837.1 15 MetaCyc: PWY-6142;MetaCyc: PWY-5723;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-7218;KEGG: 00230+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-2221;MetaCyc: PWY-7383;Reactome: R-HSA-70171;MetaCyc: PWY-7003;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5484;MetaCyc: PWY-6886;MetaCyc: PWY-1042 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Rubisco shunt";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Purine metabolism";"Entner-Doudoroff pathway I";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis";"Glycerol degradation to butanol";"Pyruvate metabolism";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)" XP_037806126.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_037827965.1 57 Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-174154;Reactome: R-HSA-2871837;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-8854050;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-6798695;Reactome: R-HSA-4641258;Reactome: R-HSA-8939236;Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-1234176 "CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"APC/C:Cdc20 mediated degradation of Securin";"FCERI mediated NF-kB activation";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neutrophil degranulation";"Degradation of DVL";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha" XP_037824596.1 7 Reactome: R-HSA-165181;Reactome: R-HSA-380972;Reactome: R-HSA-8854214;Reactome: R-HSA-5674400;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-198323 "Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK";"TBC/RABGAPs";"Constitutive Signaling by AKT1 E17K in Cancer";"TP53 Regulates Metabolic Genes";"Macroautophagy";"AKT phosphorylates targets in the cytosol" XP_037813350.1 30 KEGG: 04714+2.7.11.1;Reactome: R-HSA-69656;Reactome: R-HSA-6804759;Reactome: R-HSA-392451;Reactome: R-HSA-111447;Reactome: R-HSA-6804758;Reactome: R-HSA-9614399;Reactome: R-HSA-1257604;Reactome: R-HSA-69202;KEGG: 05163+2.7.11.1;Reactome: R-HSA-211163;Reactome: R-HSA-5218920;Reactome: R-HSA-8876198;Reactome: R-HSA-8948751;Reactome: R-HSA-198693;Reactome: R-HSA-5628897;Reactome: R-HSA-9634638;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-199418;KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1358803;Reactome: R-HSA-389513;KEGG: 04150+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-8941332;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757 "Thermogenesis";"Cyclin A:Cdk2-associated events at S phase entry";"Regulation of TP53 Activity through Association with Co-factors";"G beta:gamma signalling through PI3Kgamma";"Activation of BAD and translocation to mitochondria";"Regulation of TP53 Activity through Acetylation";"Regulation of localization of FOXO transcription factors";"PIP3 activates AKT signaling";"Cyclin E associated events during G1/S transition";"Human cytomegalovirus infection";"AKT-mediated inactivation of FOXO1A";"VEGFR2 mediated vascular permeability";"RAB GEFs exchange GTP for GDP on RABs";"Regulation of PTEN stability and activity";"AKT phosphorylates targets in the nucleus";"TP53 Regulates Metabolic Genes";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Negative regulation of the PI3K/AKT network";"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"Downregulation of ERBB2:ERBB3 signaling";"CTLA4 inhibitory signaling";"mTOR signaling pathway";"CD28 dependent PI3K/Akt signaling";"RUNX2 regulates genes involved in cell migration";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation" XP_037828334.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037813709.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_037823395.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037824906.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_037807024.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037824993.1 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" XP_037821356.1 3 MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783 "Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" XP_037816935.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037806433.1 22 Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-68877;Reactome: R-HSA-5675221;Reactome: R-HSA-5673000;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-9648025;Reactome: R-HSA-6811558;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-5358751;Reactome: R-HSA-432142;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5467337;Reactome: R-HSA-195253 "Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Negative regulation of MAPK pathway";"RAF activation";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"EML4 and NUDC in mitotic spindle formation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex" XP_037806558.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037815542.1 16 Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-8853884;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-983168 "Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037806824.1 3 Reactome: R-HSA-2299718;Reactome: R-HSA-3214841;Reactome: R-HSA-6804760 "Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines";"Regulation of TP53 Activity through Methylation" XP_037828226.1 17 Reactome: R-HSA-196780;KEGG: 00254+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00061+6.4.1.2;MetaCyc: PWY-6679;Reactome: R-HSA-200425;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5966-1;MetaCyc: PWY-5789;Reactome: R-HSA-163765;KEGG: 00720+6.4.1.2;Reactome: R-HSA-2426168;MetaCyc: PWY-5744;Reactome: R-HSA-3371599;MetaCyc: PWY-5743;MetaCyc: PWY-6722;KEGG: 00620+6.4.1.2 "Biotin transport and metabolism";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis";"Jadomycin biosynthesis";"Carnitine metabolism";"Propanoate metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"ChREBP activates metabolic gene expression";"Carbon fixation pathways in prokaryotes";"Activation of gene expression by SREBF (SREBP)";"Glyoxylate assimilation";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate cycle";"Candicidin biosynthesis";"Pyruvate metabolism" XP_037824475.1 3 Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689 "tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I" XP_037821927.1 8 Reactome: R-HSA-9619483;Reactome: R-HSA-1632852;Reactome: R-HSA-9613354;Reactome: R-HSA-380972;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-2151209;Reactome: R-HSA-6804756 "Activation of AMPK downstream of NMDARs";"Macroautophagy";"Lipophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Regulation of TP53 Activity through Phosphorylation" XP_037824414.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037823142.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037814810.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_037821332.1 10 KEGG: 00511+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-2206292;KEGG: 00604+3.2.1.23;Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23 "Other glycan degradation";"Hyaluronan uptake and degradation";"Galactose metabolism";"HS-GAG degradation";"MPS VII - Sly syndrome";"Glycosphingolipid biosynthesis - ganglio series";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Sphingolipid metabolism" XP_037824984.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_037810526.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037809556.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037810810.1 7 Reactome: R-HSA-389661;Reactome: R-HSA-5362517;KEGG: 00020+2.3.1.12;KEGG: 00010+2.3.1.12;Reactome: R-HSA-204174;KEGG: 00620+2.3.1.12;Reactome: R-HSA-70268 "Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Pyruvate metabolism" XP_037807067.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_037826293.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_037825711.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037814312.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_037823284.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037827939.1 6 Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes" XP_037815086.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037814614.1 4 Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052 "Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion" XP_037819070.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037820069.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037807215.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_037811264.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_037820411.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037806188.1 9 MetaCyc: PWY-5744;MetaCyc: PWY-7115;Reactome: R-HSA-1475029;MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-6142 "Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_037821895.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_037814218.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037817320.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037808397.1 3 KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067;Reactome: R-HSA-3322077 "Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis" XP_037806039.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037807039.1 8 MetaCyc: PWY-1861;Reactome: R-HSA-163754;KEGG: 00030+2.2.1.2;Reactome: R-HSA-71336;Reactome: R-HSA-6791462;MetaCyc: PWY-5723;Reactome: R-HSA-8950505;Reactome: R-HSA-6791055 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Pentose phosphate pathway";"Pentose phosphate pathway";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Rubisco shunt";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P" XP_037820252.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037814791.1 13 Reactome: R-HSA-177504;Reactome: R-HSA-182218;Reactome: R-HSA-2132295;Reactome: R-HSA-8964038;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900;Reactome: R-HSA-8866427;Reactome: R-HSA-416993;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-167590;Reactome: R-HSA-8856825;Reactome: R-HSA-437239 "Retrograde neurotrophin signalling";"Nef Mediated CD8 Down-regulation";"MHC class II antigen presentation";"LDL clearance";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"VLDLR internalisation and degradation";"Trafficking of GluR2-containing AMPA receptors";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Nef Mediated CD4 Down-regulation";"Cargo recognition for clathrin-mediated endocytosis";"Recycling pathway of L1" XP_037827573.1 1 Reactome: R-HSA-419771 "Opsins" XP_037813804.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_037826984.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037811951.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037823187.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037822533.1 1 Reactome: R-HSA-6804756 "Regulation of TP53 Activity through Phosphorylation" XP_037819914.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037806980.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection" XP_037827932.1 6 Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway" XP_037808261.1 19 Reactome: R-HSA-114604;Reactome: R-HSA-5625970;Reactome: R-HSA-8950505;Reactome: R-HSA-3928662;Reactome: R-HSA-5687128;Reactome: R-HSA-5627123;Reactome: R-HSA-428543;Reactome: R-HSA-5663220;Reactome: R-HSA-418885;Reactome: R-HSA-194840;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-525793;Reactome: R-HSA-5626467;Reactome: R-HSA-389359;Reactome: R-HSA-182971;Reactome: R-HSA-2029482;Reactome: R-HSA-983231;Reactome: R-HSA-8964616 "GPVI-mediated activation cascade";"RHO GTPases activate KTN1";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"EPHB-mediated forward signaling";"MAPK6/MAPK4 signaling";"RHO GTPases activate PAKs";"Inactivation of CDC42 and RAC1";"RHO GTPases Activate Formins";"DCC mediated attractive signaling";"Rho GTPase cycle";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Myogenesis";"RHO GTPases activate IQGAPs";"CD28 dependent Vav1 pathway";"EGFR downregulation";"Regulation of actin dynamics for phagocytic cup formation";"Factors involved in megakaryocyte development and platelet production";"G beta:gamma signalling through CDC42" XP_037816707.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037817091.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037825587.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-2408557 "Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis" XP_037816050.1 11 MetaCyc: PWY-6596;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6538;MetaCyc: PWY-5695;MetaCyc: PWY-6608;MetaCyc: PWY-6606;Reactome: R-HSA-8851680;MetaCyc: PWY-5497;MetaCyc: PWY-6999;MetaCyc: PWY-6607;Reactome: R-HSA-74259 "Adenosine nucleotides degradation I";"Purine metabolism";"Caffeine degradation III (bacteria, via demethylation)";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation III";"Guanosine nucleotides degradation II";"Butyrophilin (BTN) family interactions";"Purine nucleobases degradation II (anaerobic)";"Theophylline degradation";"Guanosine nucleotides degradation I";"Purine catabolism" XP_037819949.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037805565.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_037823394.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156827 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_037821388.1 56 Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-1234176;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5689603;Reactome: R-HSA-8854050;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-4641258;Reactome: R-HSA-8939236;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-69017 "Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"UCH proteinases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"Degradation of DVL";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"Degradation of AXIN";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"CDK-mediated phosphorylation and removal of Cdc6" XP_037828786.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037814257.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037813180.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_037814692.1 3 MetaCyc: PWY-8106;Reactome: R-HSA-6782315;MetaCyc: PWY-6700 "Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)" XP_037814691.1 14 Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-174411;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169 "Polymerase switching";"Dual Incision in GG-NER";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis" XP_037806611.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_037812817.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037807474.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037810965.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_037807367.1 4 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.131;KEGG: 00513+2.4.1.131;Reactome: R-HSA-4551295 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)" XP_037810673.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037816299.1 2 Reactome: R-HSA-192456;Reactome: R-HSA-975634 "Digestion of dietary lipid";"Retinoid metabolism and transport" XP_037805957.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_037823540.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037809974.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037814258.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037825250.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037826133.1 3 Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_037824962.1 15 Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-9603505;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-167290 "Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"NTRK3 as a dependence receptor";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation" XP_037814904.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037819565.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_037824548.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_037828731.1 11 Reactome: R-HSA-446205;KEGG: 00520+5.3.1.8;MetaCyc: PWY-5659;MetaCyc: PWY-7456;MetaCyc: PWY-6992;MetaCyc: PWY-7586;MetaCyc: PWY-882;Reactome: R-HSA-4043916;KEGG: 00051+5.3.1.8;MetaCyc: PWY-3861;MetaCyc: PWY-3881 "Synthesis of GDP-mannose";"Amino sugar and nucleotide sugar metabolism";"GDP-mannose biosynthesis";"Beta-(1,4)-mannan degradation";"1,5-anhydrofructose degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Defective MPI causes MPI-CDG (CDG-1b)";"Fructose and mannose metabolism";"Mannitol degradation II";"Mannitol biosynthesis" XP_037817787.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-113501 "Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1" XP_037809289.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_037812966.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" XP_037824525.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037828279.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_037826244.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-5250924;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway" XP_037811394.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037827301.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037818967.1 8 KEGG: 00240+2.7.4.9;MetaCyc: PWY-7197;MetaCyc: PWY-7187;MetaCyc: PWY-7210;MetaCyc: PWY-6545;MetaCyc: PWY-7198;MetaCyc: PWY-7184;Reactome: R-HSA-499943 "Pyrimidine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates" XP_037827368.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_037810772.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_037813138.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_037824815.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037815221.1 15 Reactome: R-HSA-9652282;Reactome: R-HSA-9665251;Reactome: R-HSA-9634285;Reactome: R-HSA-1227986;Reactome: R-HSA-1236382;Reactome: R-HSA-9665244;Reactome: R-HSA-9665250;Reactome: R-HSA-9665245;Reactome: R-HSA-9665249;Reactome: R-HSA-9664565;Reactome: R-HSA-9665247;Reactome: R-HSA-9665246;Reactome: R-HSA-8863795;Reactome: R-HSA-5637810;Reactome: R-HSA-9665233 "Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to lapatinib";"Constitutive Signaling by Overexpressed ERBB2";"Signaling by ERBB2";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Resistance of ERBB2 KD mutants to sapitinib";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to afatinib";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to osimertinib";"Resistance of ERBB2 KD mutants to neratinib";"Downregulation of ERBB2 signaling";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to trastuzumab" XP_037812767.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037806353.1 14 Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7724 "Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_037824510.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_037825251.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037815763.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037827112.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_037805717.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037812113.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_037825826.1 4 KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32 "Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism" XP_037810117.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_037825030.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-6793080 "Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion" XP_037821097.1 5 KEGG: 00900+2.2.1.7;MetaCyc: PWY-6892;MetaCyc: PWY-7560;KEGG: 00730+2.2.1.7;MetaCyc: PWY-6891 "Terpenoid backbone biosynthesis";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Methylerythritol phosphate pathway II";"Thiamine metabolism";"Thiazole biosynthesis II (aerobic bacteria)" XP_037828378.1 2 KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_037824568.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling" XP_037813874.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037812470.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037819037.1 14 KEGG: 00561+2.3.1.51;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-7417;MetaCyc: PWY-5981;MetaCyc: PWY-7587;MetaCyc: PWY-8055;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-8053;MetaCyc: PWY-7589 "Glycerolipid metabolism";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis III";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Palmitoleate biosynthesis III (cyanobacteria)" XP_037816498.1 9 Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-2426168 "Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)" XP_037823017.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_037823608.1 5 KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2 "Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation" XP_037807866.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_037810655.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037813489.1 5 KEGG: 00330+1.14.13.39;MetaCyc: PWY-4983;Reactome: R-HSA-1222556;Reactome: R-HSA-392154;KEGG: 00220+1.14.13.39 "Arginine and proline metabolism";"Nitric oxide biosynthesis II (mammals)";"ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase";"Arginine biosynthesis" XP_037814763.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_037805958.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_037815729.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_037816947.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037826364.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037808687.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037817342.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_037813977.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037822631.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_037820662.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_037815060.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_037822442.1 3 Reactome: R-HSA-500753;KEGG: 00240+1.3.5.2;MetaCyc: PWY-5686 "Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis I" XP_037824876.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_037813809.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037827108.1 6 Reactome: R-HSA-5358565;Reactome: R-HSA-5545483;Reactome: R-HSA-5632987;Reactome: R-HSA-5358606;Reactome: R-HSA-912446;Reactome: R-HSA-6796648 "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MLH1";"Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Meiotic recombination";"TP53 Regulates Transcription of DNA Repair Genes" XP_037811751.1 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" XP_037827825.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037805528.1 3 Reactome: R-HSA-1614603;Reactome: R-HSA-1614558;Reactome: R-HSA-2408508 "Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_037817515.1 10 Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-111457;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-611105;Reactome: R-HSA-111463;Reactome: R-HSA-2151201;Reactome: R-HSA-5628897;Reactome: R-HSA-3299685 "SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"Release of apoptotic factors from the mitochondria";"Formation of apoptosome";"Regulation of the apoptosome activity";"Respiratory electron transport";"SMAC (DIABLO) binds to IAPs";"Transcriptional activation of mitochondrial biogenesis";"TP53 Regulates Metabolic Genes";"Detoxification of Reactive Oxygen Species" XP_037817269.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037815327.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037810458.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_037808642.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037813260.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_037826035.1 2 Reactome: R-HSA-2243919;Reactome: R-HSA-1566948 "Crosslinking of collagen fibrils";"Elastic fibre formation" XP_037820074.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037824546.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037827704.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037810681.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037819622.1 13 MetaCyc: PWY-5030;MetaCyc: PWY-2201;MetaCyc: PWY-1722;MetaCyc: PWY-5497;MetaCyc: PWY-2161;KEGG: 00670+6.3.4.3;MetaCyc: PWY-6613;KEGG: 00720+6.3.4.3;Reactome: R-HSA-196757;MetaCyc: PWY-3841;MetaCyc: PWY-7909;KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00720+1.5.1.5+3.5.4.9 "L-histidine degradation III";"Folate transformations I";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"Folate polyglutamylation";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"Folate transformations II (plants)";"Formaldehyde oxidation VII (THF pathway)";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes" XP_037812736.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_037805922.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_037806395.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037810118.1 10 KEGG: 00052+5.1.3.2;MetaCyc: PWY-3821;MetaCyc: PWY-6397;MetaCyc: PWY-6527;Reactome: R-HSA-5609977;Reactome: R-HSA-70370;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7328;MetaCyc: PWY-6317;MetaCyc: PWY-7344 "Galactose metabolism";"D-galactose detoxification";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Stachyose degradation";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose catabolism";"Amino sugar and nucleotide sugar metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"D-galactose degradation I (Leloir pathway)";"UDP-alpha-D-galactose biosynthesis" XP_037812678.1 14 MetaCyc: PWY-6728;MetaCyc: PWY-5690;KEGG: 00190+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-561;MetaCyc: PWY-3781;MetaCyc: PWY-7279;KEGG: 00720+1.3.5.1;Reactome: R-HSA-611105;KEGG: 00020+1.3.5.1;MetaCyc: PWY-7254;MetaCyc: PWY-4302;KEGG: 00650+1.3.5.1;MetaCyc: PWY-6969 "Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Oxidative phosphorylation";"Citric acid cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Carbon fixation pathways in prokaryotes";"Respiratory electron transport";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Aerobic respiration III (alternative oxidase pathway)";"Butanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" XP_037822336.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_037806409.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-8876198;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic" XP_037807320.1 6 MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_037805377.1 10 Reactome: R-HSA-1855167;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6361;MetaCyc: PWY-4661;MetaCyc: PWY-6554;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-6369;MetaCyc: PWY-6362;MetaCyc: PWY-6372 "Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol phosphate metabolism";"Synthesis of IPs in the nucleus";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)" XP_037806292.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037813832.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037815712.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Peptide chain elongation";"Viral mRNA Translation" XP_037819019.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_037819402.1 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_037826616.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-2408557 "SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis" XP_037825393.1 16 Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-176409;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-174048 "Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B" XP_037817223.1 9 KEGG: 00020+6.4.1.1;KEGG: 00620+6.4.1.1;Reactome: R-HSA-3371599;MetaCyc: PWY-8086;Reactome: R-HSA-70263;KEGG: 00720+6.4.1.1;Reactome: R-HSA-196780;MetaCyc: PWY-6146;MetaCyc: PWY-6142 "Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis";"Carbon fixation pathways in prokaryotes";"Biotin transport and metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_037828266.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764 "Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination" XP_037808917.1 6 Reactome: R-HSA-110373;Reactome: R-HSA-73933;Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-110357;Reactome: R-HSA-73930 "Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Resolution of Abasic Sites (AP sites)";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"Displacement of DNA glycosylase by APEX1";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway" XP_037827662.1 2 Reactome: R-HSA-8950505;Reactome: R-HSA-1237112 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway" XP_037813875.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037814224.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037810327.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-68877 "COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase" XP_037805828.1 13 Reactome: R-HSA-2024101;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-6902 "CS/DS degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)" XP_037821612.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_037813227.1 10 Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-451308;Reactome: R-HSA-399719;Reactome: R-HSA-447038;Reactome: R-HSA-9609736 "Synaptic adhesion-like molecules";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Activation of Ca-permeable Kainate Receptor";"Trafficking of AMPA receptors";"NrCAM interactions";"Assembly and cell surface presentation of NMDA receptors" XP_037826027.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037819503.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_037806236.1 9 Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-6807505 "RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes" XP_037810581.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037809672.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037818383.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_037813711.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037812043.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_037819358.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" XP_037817788.1 33 Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-72086;Reactome: R-HSA-69273;Reactome: R-HSA-5696395;Reactome: R-HSA-69231;Reactome: R-HSA-6781823;Reactome: R-HSA-75953;Reactome: R-HSA-69656;Reactome: R-HSA-167200;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-8939236;Reactome: R-HSA-167161;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-76042;Reactome: R-HSA-69202;Reactome: R-HSA-167152;Reactome: R-HSA-6782210;Reactome: R-HSA-167246;Reactome: R-HSA-167160;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-73779 "RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"mRNA Capping";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of Incision Complex in GG-NER";"Cyclin D associated events in G1";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HIV Transcription Initiation";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Cyclin E associated events during G1/S transition";"Formation of HIV elongation complex in the absence of HIV Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_037806303.1 9 Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-75953 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation" XP_037819454.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_037818197.1 26 Reactome: R-HSA-1445148;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-389960;Reactome: R-HSA-8852276;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-8955332;Reactome: R-HSA-389977;Reactome: R-HSA-437239;Reactome: R-HSA-9648025;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Formation of tubulin folding intermediates by CCT/TriC";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Aggrephagy";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Carboxyterminal post-translational modifications of tubulin";"Post-chaperonin tubulin folding pathway";"Recycling pathway of L1";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"HCMV Early Events";"Cilium Assembly";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs" XP_037821355.1 3 KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II" XP_037824686.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037815716.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_037824605.1 1 Reactome: R-HSA-2465910 "MASTL Facilitates Mitotic Progression" XP_037806953.1 5 KEGG: 00260+2.3.1.37;KEGG: 00860+2.3.1.37;MetaCyc: PWY-7536;Reactome: R-HSA-189451;MetaCyc: PWY-5189 "Glycine, serine and threonine metabolism";"Porphyrin and chlorophyll metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)" XP_037812929.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037817476.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037818897.1 5 KEGG: 00250+1.2.1.88;MetaCyc: PWY-6853;Reactome: R-HSA-70688;KEGG: 00330+1.2.1.88;Reactome: R-HSA-389661 "Alanine, aspartate and glutamate metabolism";"Ethylene biosynthesis II (microbes)";"Proline catabolism";"Arginine and proline metabolism";"Glyoxylate metabolism and glycine degradation" XP_037816566.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_037827519.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_037821064.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557 "SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis" XP_037818898.1 12 MetaCyc: PWY-6683;KEGG: 00450+2.7.7.4;KEGG: 00920+2.7.7.4;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5278;Reactome: R-HSA-174362;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5340;KEGG: 00230+2.7.1.25;Reactome: R-HSA-2408550;KEGG: 00261+2.7.7.4;MetaCyc: PWY-6932 "Assimilatory sulfate reduction III";"Selenocompound metabolism";"Sulfur metabolism";"Sulfur metabolism";"Sulfite oxidation III";"Transport and synthesis of PAPS";"Purine metabolism";"Sulfate activation for sulfonation";"Purine metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Monobactam biosynthesis";"Selenate reduction" XP_037813111.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037826377.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037807127.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037814856.1 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" XP_037813421.1 9 MetaCyc: PWY-6351;Reactome: R-HSA-112043;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-416476;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;MetaCyc: PWY-7039 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule" XP_037825342.1 3 MetaCyc: PWY-6368;MetaCyc: PWY-6367;KEGG: 04070+3.1.3.78 "3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system" XP_037816941.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037806253.1 11 Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-418555 "PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"PKA activation";"Glucagon signaling in metabolic regulation";"Purine metabolism";"G alpha (z) signalling events";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events" XP_037812931.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037828527.1 4 MetaCyc: PWY-4261;Reactome: R-HSA-5661270;KEGG: 00040+2.7.1.17;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Formation of xylulose-5-phosphate";"Pentose and glucuronate interconversions";"Glycerolipid metabolism" XP_037812419.1 6 Reactome: R-HSA-8948216;Reactome: R-HSA-3000171;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8874081;Reactome: R-HSA-1650814 "Collagen chain trimerization";"Non-integrin membrane-ECM interactions";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"MET activates PTK2 signaling";"Collagen biosynthesis and modifying enzymes" XP_037817382.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037815331.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294 "SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors" XP_037827534.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037818127.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037810904.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_037826050.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_037824155.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037814306.1 8 Reactome: R-HSA-74217;Reactome: R-HSA-6798695;MetaCyc: PWY-7179-1;KEGG: 00230+3.5.4.4;MetaCyc: PWY-6611;MetaCyc: PWY-7179;MetaCyc: PWY-6609;Reactome: R-HSA-5683826 "Purine salvage";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation II";"Purine metabolism";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage III";"Surfactant metabolism" XP_037819462.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_037810771.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_037815040.1 10 MetaCyc: PWY-7909;MetaCyc: PWY-3841;Reactome: R-HSA-196757;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;MetaCyc: PWY-5030;MetaCyc: PWY-6613;MetaCyc: PWY-5497;MetaCyc: PWY-1722 "Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Folate transformations I";"L-histidine degradation III";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"Formate assimilation into 5,10-methylenetetrahydrofolate" XP_037815050.1 1 Reactome: R-HSA-70350 "Fructose catabolism" XP_037820460.1 6 Reactome: R-HSA-5099900;Reactome: R-HSA-418597;Reactome: R-HSA-416993;Reactome: R-HSA-76005;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13 "WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events";"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system" XP_037816138.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_037828676.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_037810122.1 4 KEGG: 00250+1.4.1.14;MetaCyc: PWY-6963;Reactome: R-HSA-73621;KEGG: 00910+1.4.1.14 "Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Pyrimidine catabolism";"Nitrogen metabolism" XP_037805354.1 3 Reactome: R-HSA-430039;Reactome: R-HSA-450513;Reactome: R-HSA-450385 "mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" XP_037811550.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_037818735.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037808025.1 14 Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167152 "Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat" XP_037812367.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037817361.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037828885.1 3 MetaCyc: PWY-7942;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7 "5-oxo-L-proline metabolism";"Glutathione synthesis and recycling";"Glutathione metabolism" XP_037812310.1 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" XP_037814585.1 5 Reactome: R-HSA-110328;Reactome: R-HSA-3108214;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-5221030 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA" XP_037823897.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-5576893 "NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase" XP_037821203.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_037811804.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_037813647.1 10 Reactome: R-HSA-6814122;Reactome: R-HSA-2514853;Reactome: R-HSA-8948751;Reactome: R-HSA-8934903;Reactome: R-HSA-6804756;Reactome: R-HSA-445144;Reactome: R-HSA-201688;Reactome: R-HSA-8939243;Reactome: R-HSA-6798695;Reactome: R-HSA-1483191 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Condensation of Prometaphase Chromosomes";"Regulation of PTEN stability and activity";"Receptor Mediated Mitophagy";"Regulation of TP53 Activity through Phosphorylation";"Signal transduction by L1";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Neutrophil degranulation";"Synthesis of PC" XP_037825942.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_037812164.1 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_037823154.1 17 MetaCyc: PWY-6609;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6620;Reactome: R-HSA-74259;MetaCyc: PWY-6608;MetaCyc: PWY-4202;MetaCyc: PWY-5532;MetaCyc: PWY-6644;MetaCyc: PWY-6611;KEGG: 00240+2.4.2.1;MetaCyc: PWY-7179;MetaCyc: PWY-6627;MetaCyc: PWY-7179-1;Reactome: R-HSA-6798695;Reactome: R-HSA-74217;MetaCyc: PWY-5695;KEGG: 00230+2.4.2.1 "Adenine and adenosine salvage III";"Nicotinate and nicotinamide metabolism";"Guanine and guanosine salvage";"Purine catabolism";"Guanosine nucleotides degradation III";"Arsenate detoxification I (mammalian)";"Nucleoside and nucleotide degradation (archaea)";"Fluoroacetate and fluorothreonine biosynthesis";"Adenine and adenosine salvage V";"Pyrimidine metabolism";"Purine deoxyribonucleosides degradation I";"Salinosporamide A biosynthesis";"Purine deoxyribonucleosides degradation II";"Neutrophil degranulation";"Purine salvage";"Inosine 5'-phosphate degradation";"Purine metabolism" XP_037810739.1 5 Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-1237112;KEGG: 00270+4.2.1.109;MetaCyc: PWY-4361 "Regulation of the apoptosome activity";"Formation of apoptosome";"Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_037818089.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037812456.1 3 KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1 "Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"Cyanoamino acid metabolism" XP_037824361.1 5 Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73772 "B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape" XP_037823822.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037813258.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" XP_037809009.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_037816884.1 5 Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920 "Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability" XP_037805620.1 5 Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"COPII-mediated vesicle transport" XP_037806451.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037806330.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7601;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619 "Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Juniperonate biosynthesis" XP_037814266.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037814143.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_037813093.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037811446.1 3 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901;Reactome: R-HSA-8951664 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol";"Neddylation" XP_037816551.1 15 Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693548;Reactome: R-HSA-5693565;Reactome: R-HSA-5685939;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5685942 "Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Sensing of DNA Double Strand Breaks";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through MMEJ (alt-NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)" XP_037828218.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_037821358.1 3 MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783 "Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" XP_037814588.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_037820659.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339 "Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane" XP_037814916.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037823652.1 6 Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-418592 "G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1" XP_037826839.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_037809984.1 5 KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;Reactome: R-HSA-197264 "Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging" XP_037810294.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_037812273.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037812060.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_037812324.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037822050.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_037821843.1 4 KEGG: 00473+5.1.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-8072;MetaCyc: PWY-8040 "D-Alanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine racemization";"Ansatrienin biosynthesis" XP_037821766.1 44 Reactome: R-HSA-5674499;Reactome: R-HSA-6802952;Reactome: R-HSA-456926;Reactome: R-HSA-112409;Reactome: R-HSA-9627069;Reactome: R-HSA-5675221;Reactome: R-HSA-5654732;Reactome: R-HSA-445144;Reactome: R-HSA-5668599;Reactome: R-HSA-5654727;Reactome: R-HSA-8940973;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-881907;Reactome: R-HSA-5654733;Reactome: R-HSA-74749;Reactome: R-HSA-2559582;Reactome: R-HSA-5663213;Reactome: R-HSA-202670;Reactome: R-HSA-444257;Reactome: R-HSA-6811558;Reactome: R-HSA-5674135;Reactome: R-HSA-1295596;Reactome: R-HSA-5654726;Reactome: R-HSA-9635465;Reactome: R-HSA-170968;Reactome: R-HSA-8939211;Reactome: R-HSA-162658;Reactome: R-HSA-6802955;KEGG: 04150+2.7.11.24;Reactome: R-HSA-3371453;Reactome: R-HSA-450341;Reactome: R-HSA-6802948;Reactome: R-HSA-9634638;Reactome: R-HSA-8943724;Reactome: R-HSA-375165;Reactome: R-HSA-9649948;Reactome: R-HSA-198753;Reactome: R-HSA-5673001;Reactome: R-HSA-879415;Reactome: R-HSA-982772;Reactome: R-HSA-2871796;Reactome: R-HSA-2029482;Reactome: R-HSA-6802946 "Negative feedback regulation of MAPK pathway";"Signaling by BRAF and RAF fusions";"Thrombin signalling through proteinase activated receptors (PARs)";"RAF-independent MAPK1/3 activation";"Regulation of the apoptosome activity";"Negative regulation of MAPK pathway";"Negative regulation of FGFR3 signaling";"Signal transduction by L1";"RHO GTPases Activate NADPH Oxidases";"Negative regulation of FGFR2 signaling";"RUNX2 regulates osteoblast differentiation";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"Gastrin-CREB signalling pathway via PKC and MAPK";"Negative regulation of FGFR4 signaling";"Signal attenuation";"Senescence-Associated Secretory Phenotype (SASP)";"RHO GTPases Activate WASPs and WAVEs";"ERKs are inactivated";"RSK activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"MAP2K and MAPK activation";"Spry regulation of FGF signaling";"Negative regulation of FGFR1 signaling";"Suppression of apoptosis";"Frs2-mediated activation";"ESR-mediated signaling";"Golgi Cisternae Pericentriolar Stack Reorganization";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"mTOR signaling pathway";"Regulation of HSF1-mediated heat shock response";"Activation of the AP-1 family of transcription factors";"Signaling by high-kinase activity BRAF mutants";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Regulation of PTEN gene transcription";"NCAM signaling for neurite out-growth";"Signaling downstream of RAS mutants";"ERK/MAPK targets";"RAF/MAP kinase cascade";"Advanced glycosylation endproduct receptor signaling";"Growth hormone receptor signaling";"FCERI mediated MAPK activation";"Regulation of actin dynamics for phagocytic cup formation";"Signaling by moderate kinase activity BRAF mutants" XP_037812665.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_037824612.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7802 "Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)" XP_037809043.1 4 Reactome: R-HSA-186763;Reactome: R-HSA-8875656;Reactome: R-HSA-912631;Reactome: R-HSA-8875555 "Downstream signal transduction";"MET receptor recycling";"Regulation of signaling by CBL";"MET activates RAP1 and RAC1" XP_037811883.1 7 Reactome: R-HSA-5635838;Reactome: R-HSA-5658034;Reactome: R-HSA-5632684;Reactome: R-HSA-5632681;Reactome: R-HSA-5362798;Reactome: R-HSA-373080;Reactome: R-HSA-5358346 "Activation of SMO";"HHAT G278V abrogates palmitoylation of Hh-Np";"Hedgehog 'on' state";"Ligand-receptor interactions";"Release of Hh-Np from the secreting cell";"Class B/2 (Secretin family receptors)";"Hedgehog ligand biogenesis" XP_037821035.1 6 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Neutrophil degranulation" XP_037812841.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_037805803.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037825966.1 5 Reactome: R-HSA-2559580;Reactome: R-HSA-450341;Reactome: R-HSA-450321;Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24 "Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation";"mTOR signaling pathway" XP_037818732.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037809258.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037822340.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_037807299.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226 "Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037816853.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037824150.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_037806345.1 14 KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7724 "Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_037807153.1 13 KEGG: 00980+2.5.1.18;Reactome: R-HSA-196836;MetaCyc: PWY-7112;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-6842;MetaCyc: PWY-7533;MetaCyc: PWY-2261;MetaCyc: PWY-4061;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;KEGG: 00053+1.8.5.1;KEGG: 00983+2.5.1.18;MetaCyc: PWY-6370 "Metabolism of xenobiotics by cytochrome P450";"Vitamin C (ascorbate) metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Gliotoxin biosynthesis";"Ascorbate glutathione cycle";"Glutathione-mediated detoxification I";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Ascorbate and aldarate metabolism";"Drug metabolism - other enzymes";"Ascorbate recycling (cytosolic)" XP_037808595.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_037822788.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037811193.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037818844.1 7 MetaCyc: PWY-8043;Reactome: R-HSA-174403;MetaCyc: PWY-7255;KEGG: 00270+6.3.2.2;Reactome: R-HSA-5578999;KEGG: 00480+6.3.2.2;MetaCyc: PWY-6840 "Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Ergothioneine biosynthesis I (bacteria)";"Cysteine and methionine metabolism";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione metabolism";"Homoglutathione biosynthesis" XP_037818196.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_037821447.1 19 Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-936837;Reactome: R-HSA-5576892;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-6802952;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-3371571 "Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion transport by P-type ATPases";"Phase 0 - rapid depolarisation";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by BRAF and RAF fusions";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"HSF1-dependent transactivation" XP_037810005.1 13 Reactome: R-HSA-8948216;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-2214320;Reactome: R-HSA-2243919;Reactome: R-HSA-1474244;Reactome: R-HSA-2022090;Reactome: R-HSA-216083;Reactome: R-HSA-1650814;Reactome: R-HSA-3000157;Reactome: R-HSA-1442490;Reactome: R-HSA-419037;Reactome: R-HSA-186797 "Collagen chain trimerization";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"Anchoring fibril formation";"Crosslinking of collagen fibrils";"Extracellular matrix organization";"Assembly of collagen fibrils and other multimeric structures";"Integrin cell surface interactions";"Collagen biosynthesis and modifying enzymes";"Laminin interactions";"Collagen degradation";"NCAM1 interactions";"Signaling by PDGF" XP_037815581.1 8 Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949 "Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin" XP_037814042.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004 "Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity" XP_037805373.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_037809246.1 27 Reactome: R-HSA-3232142;Reactome: R-HSA-3371453;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-9610379 "SUMOylation of ubiquitinylation proteins";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events" XP_037823894.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase" XP_037814611.1 4 Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_037805929.1 6 Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-390471 "Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis" XP_037807071.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_037810401.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037816461.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037824992.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_037813775.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_037813518.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_037822763.1 3 Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968 "Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6" XP_037828441.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_037820722.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_037815753.1 27 Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-9610379 "SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events" XP_037817294.1 4 KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3 "Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism" XP_037813860.1 2 Reactome: R-HSA-5673001;Reactome: R-HSA-8853659 "RAF/MAP kinase cascade";"RET signaling" XP_037822502.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037823185.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037819468.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_037812171.1 3 KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894 "Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation" XP_037805284.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037814888.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_037814901.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037822339.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_037825646.1 10 Reactome: R-HSA-2565942;Reactome: R-HSA-5607764;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-5684264;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664 "Regulation of PLK1 Activity at G2/M Transition";"CLEC7A (Dectin-1) signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation" XP_037822955.1 6 Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-212676 "Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" XP_037826038.1 4 Reactome: R-HSA-1237112;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361 "Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_037817685.1 5 Reactome: R-HSA-3270619;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-6798695;Reactome: R-HSA-164843 "IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"Neutrophil degranulation";"2-LTR circle formation" XP_037810342.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037806814.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_037822434.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156827 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_037817383.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037812198.1 27 Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-159230 "HCMV Early Events";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA" XP_037814886.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_037813272.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037827320.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037821276.1 5 Reactome: R-HSA-983231;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436 "Factors involved in megakaryocyte development and platelet production";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic" XP_037827637.1 8 KEGG: 00620+1.1.1.27;MetaCyc: PWY-8086;KEGG: 00640+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00270+1.1.1.27;KEGG: 00010+1.1.1.27;MetaCyc: PWY-6901;Reactome: R-HSA-70268 "Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Propanoate metabolism";"Pyruvate fermentation to (S)-lactate";"Cysteine and methionine metabolism";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Pyruvate metabolism" XP_037815207.1 7 KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis" XP_037816804.1 1 Reactome: R-HSA-1483166 "Synthesis of PA" XP_037825503.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_037828087.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_037808588.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037811086.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862 "HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_037818153.1 6 MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085 "Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_037816245.1 5 KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-8013 "Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III" XP_037810826.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_037806161.1 42 Reactome: R-HSA-5625886;Reactome: R-HSA-5693565;Reactome: R-HSA-73728;Reactome: R-HSA-5250924;Reactome: R-HSA-69473;Reactome: R-HSA-606279;Reactome: R-HSA-1221632;Reactome: R-HSA-110331;Reactome: R-HSA-9018519;Reactome: R-HSA-4551638;Reactome: R-HSA-8939236;Reactome: R-HSA-212300;Reactome: R-HSA-201722;Reactome: R-HSA-427413;Reactome: R-HSA-110328;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-9609690;Reactome: R-HSA-73772;Reactome: R-HSA-1912408;Reactome: R-HSA-3214841;Reactome: R-HSA-110330;Reactome: R-HSA-3214858;Reactome: R-HSA-5578749;Reactome: R-HSA-977225;Reactome: R-HSA-912446;Reactome: R-HSA-5617472;Reactome: R-HSA-427359;Reactome: R-HSA-3214847;Reactome: R-HSA-9616222;Reactome: R-HSA-9610379;Reactome: R-HSA-5334118;Reactome: R-HSA-171306;Reactome: R-HSA-3214842;Reactome: R-HSA-2299718;Reactome: R-HSA-2559586;Reactome: R-HSA-2559580;Reactome: R-HSA-8936459;Reactome: R-HSA-110329;Reactome: R-HSA-427389;Reactome: R-HSA-2559582;Reactome: R-HSA-3214815 "Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RNA Polymerase I Promoter Opening";"B-WICH complex positively regulates rRNA expression";"G2/M DNA damage checkpoint";"Deposition of new CENPA-containing nucleosomes at the centromere";"Meiotic synapsis";"Cleavage of the damaged purine";"Estrogen-dependent gene expression";"SUMOylation of chromatin organization proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"PRC2 methylates histones and DNA";"Formation of the beta-catenin:TCF transactivating complex";"NoRC negatively regulates rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"HCMV Early Events";"RNA Polymerase I Promoter Escape";"Pre-NOTCH Transcription and Translation";"PKMTs methylate histone lysines";"Recognition and association of DNA glycosylase with site containing an affected purine";"RMTs methylate histone arginines";"Transcriptional regulation by small RNAs";"Amyloid fiber formation";"Meiotic recombination";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SIRT1 negatively regulates rRNA expression";"HATs acetylate histones";"Transcriptional regulation of granulopoiesis";"HCMV Late Events";"DNA methylation";"Packaging Of Telomere Ends";"HDMs demethylate histones";"Condensation of Prophase Chromosomes";"DNA Damage/Telomere Stress Induced Senescence";"Oxidative Stress Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Cleavage of the damaged pyrimidine";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Senescence-Associated Secretory Phenotype (SASP)";"HDACs deacetylate histones" XP_037821795.1 7 Reactome: R-HSA-210500;Reactome: R-HSA-5628897;KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2;KEGG: 00250+3.5.1.2 "Glutamate Neurotransmitter Release Cycle";"TP53 Regulates Metabolic Genes";"D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism" XP_037819385.1 17 Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-72706 "Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Peptide chain elongation";"Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037818923.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_037820261.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037810563.1 13 MetaCyc: PWY-5913;MetaCyc: PWY-6728;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5392;Reactome: R-HSA-71403;MetaCyc: PWY-5537;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.5 "Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism" XP_037821313.1 3 Reactome: R-HSA-400206;Reactome: R-HSA-427413;Reactome: R-HSA-8936459 "Regulation of lipid metabolism by PPARalpha";"NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_037821786.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_037807173.1 2 Reactome: R-HSA-8862803;Reactome: R-HSA-69273 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition" XP_037807289.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339 "Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane" XP_037826727.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_037812178.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_037822421.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_037821103.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037806471.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway" XP_037811680.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_037815550.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_037822231.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_037806717.1 10 Reactome: R-HSA-3214847;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-75953 "HATs acetylate histones";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation" XP_037818821.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037810864.1 29 Reactome: R-HSA-5358565;Reactome: R-HSA-6804756;Reactome: R-HSA-68962;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-3108214;Reactome: R-HSA-174437;Reactome: R-HSA-110312;Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-69166;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-3371511;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-69473;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-3371453;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-6783310;Reactome: R-HSA-5696397;Reactome: R-HSA-110320;Reactome: R-HSA-912446;Reactome: R-HSA-5358606 "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Regulation of TP53 Activity through Phosphorylation";"Activation of the pre-replicative complex";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"SUMOylation of DNA damage response and repair proteins";"Removal of the Flap Intermediate from the C-strand";"Translesion synthesis by REV1";"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"Removal of the Flap Intermediate";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"HSF1 activation";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Regulation of HSF1-mediated heat shock response";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Fanconi Anemia Pathway";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)" XP_037806842.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_037815248.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037825754.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-6784531;Reactome: R-HSA-77595;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"tRNA processing in the nucleus";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway" XP_037819277.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_037820257.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037817135.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037823076.1 52 Reactome: R-HSA-167238;Reactome: R-HSA-72086;Reactome: R-HSA-72165;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73776;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-72203;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-113418;Reactome: R-HSA-749476;Reactome: R-HSA-6782135;Reactome: R-HSA-203927;Reactome: R-HSA-8851708;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-6781823;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-5601884;Reactome: R-HSA-167242;Reactome: R-HSA-5617472;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-6803529;Reactome: R-HSA-73980;Reactome: R-HSA-167160;Reactome: R-HSA-167246;Reactome: R-HSA-5578749;Reactome: R-HSA-72163;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-76061;Reactome: R-HSA-168325;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-6796648 "Pausing and recovery of Tat-mediated HIV elongation";"mRNA Capping";"mRNA Splicing - Minor Pathway";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Promoter Escape";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"Formation of the Early Elongation Complex";"RNA Polymerase III Abortive And Retractive Initiation";"Dual incision in TC-NER";"MicroRNA (miRNA) biogenesis";"Signaling by FGFR2 IIIa TM";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"PIWI-interacting RNA (piRNA) biogenesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"FGFR2 alternative splicing";"RNA Polymerase III Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated elongation of the HIV-1 transcript";"Transcriptional regulation by small RNAs";"mRNA Splicing - Major Pathway";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Viral Messenger RNA Synthesis";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes" XP_037807735.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037816211.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_037827236.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_037813485.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-5689880 "Mitochondrial calcium ion transport";"Ub-specific processing proteases" XP_037811722.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_037826448.1 3 Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695 "Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation" XP_037825253.1 1 Reactome: R-HSA-5657655 "MGMT-mediated DNA damage reversal" XP_037817858.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037813228.1 10 Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-451308;Reactome: R-HSA-442982;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-447038 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Activation of Ca-permeable Kainate Receptor";"Ras activation upon Ca2+ influx through NMDA receptor";"Synaptic adhesion-like molecules";"Long-term potentiation";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"NrCAM interactions" XP_037826325.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_037827509.1 3 Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import" XP_037817030.1 3 Reactome: R-HSA-1660662;MetaCyc: PWY-7277;KEGG: 00600+3.1.4.12 "Glycosphingolipid metabolism";"Sphingolipid biosynthesis (mammals)";"Sphingolipid metabolism" XP_037828528.1 4 MetaCyc: PWY-4261;Reactome: R-HSA-5661270;KEGG: 00561+2.7.1.30;KEGG: 00040+2.7.1.17 "Glycerol degradation I";"Formation of xylulose-5-phosphate";"Glycerolipid metabolism";"Pentose and glucuronate interconversions" XP_037818605.1 5 Reactome: R-HSA-6798695;MetaCyc: PWY-5189;KEGG: 00860+4.2.1.24;Reactome: R-HSA-189451;MetaCyc: PWY-5188 "Neutrophil degranulation";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)" XP_037809344.1 5 Reactome: R-HSA-432720;Reactome: R-HSA-2206305;Reactome: R-HSA-2022857;KEGG: 00531+3.1.6.14;Reactome: R-HSA-6798695 "Lysosome Vesicle Biogenesis";"MPS IIID - Sanfilippo syndrome D";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Neutrophil degranulation" XP_037818092.1 3 Reactome: R-HSA-3065676;Reactome: R-HSA-3065678;Reactome: R-HSA-983168 "SUMO is conjugated to E1 (UBA2:SAE1)";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037813611.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_037822891.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_037817721.1 3 KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268;MetaCyc: PWY-5386 "Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I" XP_037809743.1 7 Reactome: R-HSA-204174;KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-70268;KEGG: 00020+1.2.4.1;Reactome: R-HSA-389661;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid" XP_037819455.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_037807734.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037813658.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214815 "NoRC negatively regulates rRNA expression";"HDACs deacetylate histones" XP_037816309.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037828343.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037818760.1 7 Reactome: R-HSA-6807878;Reactome: R-HSA-6798695;Reactome: R-HSA-264870;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-373753 "COPI-mediated anterograde transport";"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"Nephrin family interactions" XP_037806770.1 7 KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis" XP_037812806.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037806760.1 7 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway" XP_037808062.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_037812757.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037820684.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_037821922.1 5 Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897 "Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes" XP_037812311.1 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" XP_037821916.1 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_037820251.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037819505.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_037808175.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037819599.1 2 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_037811164.1 6 Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-2173788;Reactome: R-HSA-8863795;Reactome: R-HSA-8948751;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Downregulation of TGF-beta receptor signaling";"Downregulation of ERBB2 signaling";"Regulation of PTEN stability and activity";"Protein ubiquitination" XP_037805902.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_037819558.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_037818710.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037812866.1 4 Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis" XP_037817151.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037828286.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037806284.1 3 Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619 "Purine salvage";"Purine metabolism";"Adenine and adenosine salvage VI" XP_037809616.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037817179.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_037816085.1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_037806218.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_037813114.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037814260.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037816798.1 5 Reactome: R-HSA-4793954;MetaCyc: PWY-7918;MetaCyc: PWY-7919;Reactome: R-HSA-532668;KEGG: 00510+3.2.1.106 "Defective MOGS causes MOGS-CDG (CDG-2b)";"Protein N-glycosylation processing phase (yeast)";"Protein N-glycosylation processing phase (plants and animals)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"N-Glycan biosynthesis" XP_037806416.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_037816923.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_037819293.1 6 Reactome: R-HSA-6803207;Reactome: R-HSA-6803205;Reactome: R-HSA-6803204;Reactome: R-HSA-139915;Reactome: R-HSA-6804759;Reactome: R-HSA-6803211 "TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Activation of PUMA and translocation to mitochondria";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Death Receptors and Ligands" XP_037822204.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.9 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_037813789.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_037821883.1 25 Reactome: R-HSA-8940973;Reactome: R-HSA-8941858;Reactome: R-HSA-8936459;Reactome: R-HSA-8877330;Reactome: R-HSA-8951911;Reactome: R-HSA-8951936;Reactome: R-HSA-8939247;Reactome: R-HSA-9018519;Reactome: R-HSA-8931987;Reactome: R-HSA-8939242;Reactome: R-HSA-8939236;Reactome: R-HSA-8941326;Reactome: R-HSA-8939256;Reactome: R-HSA-8941332;Reactome: R-HSA-8939246;Reactome: R-HSA-9616222;Reactome: R-HSA-8878166;Reactome: R-HSA-8941333;Reactome: R-HSA-8941284;Reactome: R-HSA-8935964;Reactome: R-HSA-8949275;Reactome: R-HSA-8939243;Reactome: R-HSA-8934593;Reactome: R-HSA-8939902;Reactome: R-HSA-8939245 "RUNX2 regulates osteoblast differentiation";"Regulation of RUNX3 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX3 regulates RUNX1-mediated transcription";"RUNX3 regulates p14-ARF";"RUNX1 regulates transcription of genes involved in interleukin signaling";"Estrogen-dependent gene expression";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX2 regulates bone development";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX2 regulates genes involved in cell migration";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"Transcriptional regulation of granulopoiesis";"Transcriptional regulation by RUNX2";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX2 regulates chondrocyte maturation";"RUNX1 regulates expression of components of tight junctions";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of RUNX1 Expression and Activity";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in BCR signaling" XP_037808103.1 2 Reactome: R-HSA-389957;Reactome: R-HSA-8953750 "Prefoldin mediated transfer of substrate to CCT/TriC";"Transcriptional Regulation by E2F6" XP_037816004.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823 "DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex" XP_037814547.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037807732.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037807477.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037824814.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_037806807.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037812400.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037816289.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_037819852.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" XP_037806377.1 4 KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;MetaCyc: PWY-7193 "Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I" XP_037828628.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_037816640.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-5663220 "Signaling by ROBO receptors";"RHO GTPases Activate Formins" XP_037810199.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037822514.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_037806906.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_037817257.1 9 MetaCyc: PWY-7039;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-416476;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;Reactome: R-HSA-112043;MetaCyc: PWY-6351 "Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis" XP_037808816.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_037806867.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" XP_037814382.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037811142.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_037816697.1 3 MetaCyc: PWY-6100;KEGG: 00310+1.14.11.8;Reactome: R-HSA-71262 "L-carnitine biosynthesis";"Lysine degradation";"Carnitine synthesis" XP_037826381.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_037818061.1 2 Reactome: R-HSA-1912420;KEGG: 00514+2.4.1.222 "Pre-NOTCH Processing in Golgi";"Other types of O-glycan biosynthesis" XP_037827369.1 7 KEGG: 00521+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-4702;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-6363 "Streptomycin biosynthesis";"Myo-inositol biosynthesis";"Phytate degradation I";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation" XP_037824547.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037816432.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7602 "Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_037828272.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_037810399.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037809151.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_037824672.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037805724.1 4 MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.12;MetaCyc: PWY-7887 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation" XP_037807507.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037827077.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_037828297.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037821149.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037827370.1 7 KEGG: 04070+3.1.3.25;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25;MetaCyc: PWY-2301 "Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Phytate degradation I";"Streptomycin biosynthesis";"Myo-inositol biosynthesis" XP_037822875.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037807276.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037811025.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037817224.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037821399.1 17 Reactome: R-HSA-3371453;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1221632;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6783310;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-69473;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6796648 "Regulation of HSF1-mediated heat shock response";"mTOR signaling pathway";"Meiotic synapsis";"Relaxin signaling pathway";"Fanconi Anemia Pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"G2/M DNA damage checkpoint";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"TP53 Regulates Transcription of DNA Repair Genes" XP_037826371.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037823613.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037828588.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-1236974 "SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway" XP_037810124.1 4 KEGG: 00250+1.4.1.14;KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621;MetaCyc: PWY-6963 "Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Pyrimidine catabolism";"Ammonia assimilation cycle I" XP_037807904.1 18 KEGG: 00330+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00220+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-6643;KEGG: 00400+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-7383;MetaCyc: PWY-5913;MetaCyc: PWY-6638 "Arginine and proline metabolism";"Carbon fixation in photosynthetic organisms";"Novobiocin biosynthesis";"Alanine, aspartate and glutamate metabolism";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Arginine biosynthesis";"Phenylalanine metabolism";"(R)-cysteate degradation";"Coenzyme M biosynthesis II";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Anaerobic energy metabolism (invertebrates, cytosol)";"Partial TCA cycle (obligate autotrophs)";"Sulfolactate degradation III" XP_037806771.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection" XP_037811840.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-6811438 "RAB geranylgeranylation";"Intra-Golgi traffic" XP_037813805.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_037819971.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037808786.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_037809256.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_037817207.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037808793.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_037821236.1 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" YP_001425550.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_037828241.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037824985.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_037812926.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037809101.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-450513 "ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_037811351.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037816484.1 29 Reactome: R-HSA-167158;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-73772;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-77075;Reactome: R-HSA-427413;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-6781823;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-73863;Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-167152;Reactome: R-HSA-6782210 "Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Transcription of the HIV genome";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"NoRC negatively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"RNA Polymerase I Transcription Termination";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_037814851.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-1358803;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination" XP_037812018.1 3 Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_037816903.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037808360.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037807497.1 4 Reactome: R-HSA-189451;MetaCyc: PWY-5188;MetaCyc: PWY-5189;KEGG: 00860+2.5.1.61 "Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism" XP_037820256.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037820763.1 4 Reactome: R-HSA-352230;Reactome: R-HSA-71240;Reactome: R-HSA-5660862;Reactome: R-HSA-210991 "Amino acid transport across the plasma membrane";"Tryptophan catabolism";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Basigin interactions" XP_037809983.1 5 MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21;Reactome: R-HSA-1368108;Reactome: R-HSA-6798695;Reactome: R-HSA-197264 "Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Neutrophil degranulation";"Nicotinamide salvaging" XP_037806748.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037827110.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase" XP_037816353.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037814824.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037820452.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_037817038.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037823136.1 29 Reactome: R-HSA-167152;Reactome: R-HSA-6782210;Reactome: R-HSA-167246;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-6781823;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-167172;Reactome: R-HSA-113418;Reactome: R-HSA-6782135;Reactome: R-HSA-167161;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-73772;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167162 "Formation of HIV elongation complex in the absence of HIV Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"Transcription of the HIV genome";"Formation of the Early Elongation Complex";"Dual incision in TC-NER";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape" XP_037805495.1 4 MetaCyc: PWY-5737;MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2;Reactome: R-HSA-70688 "(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Proline catabolism" XP_037825839.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380284 "AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_037823175.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_037811388.1 6 MetaCyc: PWY-5067;MetaCyc: PWY-622;Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900 "Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)" XP_037811520.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037810631.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_037823081.1 12 Reactome: R-HSA-2132295;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-381038;Reactome: R-HSA-5620912;Reactome: R-HSA-380284 "MHC class II antigen presentation";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"XBP1(S) activates chaperone genes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_037828725.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037814418.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_037819612.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037807106.1 4 Reactome: R-HSA-352230;Reactome: R-HSA-71240;Reactome: R-HSA-210991;Reactome: R-HSA-5660862 "Amino acid transport across the plasma membrane";"Tryptophan catabolism";"Basigin interactions";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)" XP_037808045.1 10 MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-6886;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-8004;Reactome: R-HSA-70263;KEGG: 00710+2.7.2.3;MetaCyc: PWY-6901;KEGG: 00010+2.7.2.3 "Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Entner-Doudoroff pathway I";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis" XP_037818412.1 14 MetaCyc: PWY-7409;Reactome: R-HSA-975634;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;MetaCyc: PWY-7416 "Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)" XP_037818665.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_037817781.1 3 MetaCyc: PWY-6689;MetaCyc: PWY-7803;Reactome: R-HSA-6784531 "Trna splicing I";"Trna splicing II";"tRNA processing in the nucleus" XP_037828261.1 3 Reactome: R-HSA-110314;Reactome: R-HSA-6783310;Reactome: R-HSA-5689880 "Recognition of DNA damage by PCNA-containing replication complex";"Fanconi Anemia Pathway";"Ub-specific processing proteases" XP_037808922.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037828005.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037823326.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037817362.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037822701.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-192823 "Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation" XP_037822965.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_037825872.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037827599.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_037814094.1 40 Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-72203;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-8851708;Reactome: R-HSA-203927;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-167161;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-5601884;Reactome: R-HSA-9018519;Reactome: R-HSA-6781823;Reactome: R-HSA-75953;Reactome: R-HSA-167238;Reactome: R-HSA-72165;Reactome: R-HSA-72086;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-168325;Reactome: R-HSA-167172;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-6803529;Reactome: R-HSA-674695;Reactome: R-HSA-5617472;Reactome: R-HSA-6781827;Reactome: R-HSA-167242;Reactome: R-HSA-167160;Reactome: R-HSA-167243;Reactome: R-HSA-72163;Reactome: R-HSA-167246;Reactome: R-HSA-5578749;Reactome: R-HSA-6782210;Reactome: R-HSA-167152 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"Signaling by FGFR2 IIIa TM";"MicroRNA (miRNA) biogenesis";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"HIV Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PIWI-interacting RNA (piRNA) biogenesis";"Estrogen-dependent gene expression";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Splicing - Minor Pathway";"mRNA Capping";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"Viral Messenger RNA Synthesis";"Transcription of the HIV genome";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"FGFR2 alternative splicing";"RNA Polymerase II Pre-transcription Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated HIV elongation arrest and recovery";"mRNA Splicing - Major Pathway";"Tat-mediated elongation of the HIV-1 transcript";"Transcriptional regulation by small RNAs";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat" XP_037818862.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_037818910.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037810657.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037821360.1 3 MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33 "Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_037827692.1 4 Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568 "HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_037815089.1 1 Reactome: R-HSA-5624958 "ARL13B-mediated ciliary trafficking of INPP5E" XP_037817676.1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814 "Collagen chain trimerization";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes" XP_037812379.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037826821.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_037817852.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037806547.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_037820449.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037815034.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037823080.1 12 Reactome: R-HSA-8854518;Reactome: R-HSA-6807878;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-381038;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2132295;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497 "AURKA Activation by TPX2";"COPI-mediated anterograde transport";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"XBP1(S) activates chaperone genes";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_037822805.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037817371.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037828289.1 4 Reactome: R-HSA-1268020;Reactome: R-HSA-3371453;Reactome: R-HSA-8950505;Reactome: R-HSA-8949613 "Mitochondrial protein import";"Regulation of HSF1-mediated heat shock response";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Cristae formation" XP_037821882.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72702 "Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition" XP_037822256.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_037813787.1 3 Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification" XP_037824566.1 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" XP_037821881.1 2 Reactome: R-HSA-5619061;Reactome: R-HSA-425397 "Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules" XP_037812410.1 5 MetaCyc: PWY-5523;MetaCyc: PWY-6168;KEGG: 00740+2.7.1.26;MetaCyc: PWY-7863;Reactome: R-HSA-196843 "5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Flavin biosynthesis III (fungi)";"Riboflavin metabolism";"Roseoflavin biosynthesis";"Vitamin B2 (riboflavin) metabolism" XP_037816677.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037809527.1 4 Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037827063.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037828690.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037816709.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037806779.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_037817815.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037822829.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037813327.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037818295.1 6 KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-3299685;Reactome: R-HSA-6798695;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9615017 "Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import";"Detoxification of Reactive Oxygen Species";"Neutrophil degranulation";"Tryptophan metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes" XP_037812784.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037810244.1 2 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol" XP_037825275.1 6 MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" XP_037806151.1 57 Reactome: R-HSA-5689603;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-6798695;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-187577;Reactome: R-HSA-68949;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-69017;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-174154;Reactome: R-HSA-2871837;Reactome: R-HSA-180534 "UCH proteinases";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"Neutrophil degranulation";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"APC/C:Cdc20 mediated degradation of Securin";"FCERI mediated NF-kB activation";"Vpu mediated degradation of CD4" XP_037826284.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037812493.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_037806808.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_037808319.1 3 Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400 "Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER" XP_037806868.1 7 KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway" XP_037807216.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037822280.1 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" XP_037813515.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_037812040.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_037809623.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037806410.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network" XP_037806354.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7619;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation" XP_037814448.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_037817233.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_037828825.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037826726.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_037824963.1 15 Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-9603505;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167287 "Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"NTRK3 as a dependence receptor";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery" XP_037815087.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037814946.1 4 Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-418594 "Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT";"G alpha (i) signalling events" XP_037815169.1 4 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex" XP_037806255.1 8 Reactome: R-HSA-8943724;Reactome: R-HSA-9609690;Reactome: R-HSA-2559580;Reactome: R-HSA-8953750;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-212300;Reactome: R-HSA-4551638 "Regulation of PTEN gene transcription";"HCMV Early Events";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by E2F6";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins" XP_037808471.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947 "Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription" XP_037806306.1 4 MetaCyc: PWY-6823;MetaCyc: PWY-7887;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.12 "Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_037806983.1 3 Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097 "Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway" XP_037824247.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_037820458.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_037813015.1 9 Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167162 "RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape" XP_037828134.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_037807307.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037809453.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037815119.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037816488.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_037805469.1 10 Reactome: R-HSA-975634;MetaCyc: PWY-7394;MetaCyc: PWY-5691;KEGG: 00230+3.5.2.17;Reactome: R-HSA-2453902;Reactome: R-HSA-977225;Reactome: R-HSA-6798695;Reactome: R-HSA-3000171;Reactome: R-HSA-2453864;MetaCyc: PWY-7849 "Retinoid metabolism and transport";"Urate conversion to allantoin II";"Urate conversion to allantoin I";"Purine metabolism";"The canonical retinoid cycle in rods (twilight vision)";"Amyloid fiber formation";"Neutrophil degranulation";"Non-integrin membrane-ECM interactions";"Retinoid cycle disease events";"Urate conversion to allantoin III" XP_037813706.1 57 Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-68949;Reactome: R-HSA-174178;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-6798695;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-2871837;Reactome: R-HSA-180534;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-69017;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974 "Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"Neutrophil degranulation";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of AXIN";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"FCERI mediated NF-kB activation";"Vpu mediated degradation of CD4";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway" XP_037826966.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037807746.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-264870;Reactome: R-HSA-6794361 "Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins";"Neurexins and neuroligins" XP_037819246.1 12 Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-9017802;Reactome: R-HSA-9013507;Reactome: R-HSA-977225;Reactome: R-HSA-2644606;Reactome: R-HSA-205043;Reactome: R-HSA-2894862;Reactome: R-HSA-193692;Reactome: R-HSA-1251985;Reactome: R-HSA-3928665;Reactome: R-HSA-9013700 "NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulated proteolysis of p75NTR";"Nuclear signaling by ERBB4";"EPH-ephrin mediated repulsion of cells";"NOTCH4 Activation and Transmission of Signal to the Nucleus" XP_037812420.1 6 Reactome: R-HSA-1442490;Reactome: R-HSA-3000171;Reactome: R-HSA-8948216;Reactome: R-HSA-8874081;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090 "Collagen degradation";"Non-integrin membrane-ECM interactions";"Collagen chain trimerization";"MET activates PTK2 signaling";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures" XP_037824813.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_037819610.1 56 Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5689603;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813 "Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"UCH proteinases";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids" XP_037827973.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037805995.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_037809965.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037812381.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037809673.1 12 KEGG: 00230+6.3.3.1;KEGG: 00970+2.1.2.9;MetaCyc: PWY-6613;MetaCyc: PWY-6277;Reactome: R-HSA-196780;KEGG: 00670+2.1.2.2;Reactome: R-HSA-73817;KEGG: 00230+2.1.2.2;MetaCyc: PWY-6122;KEGG: 00230+6.3.4.13;MetaCyc: PWY-6121;KEGG: 00670+2.1.2.9 "Purine metabolism";"Aminoacyl-tRNA biosynthesis";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Biotin transport and metabolism";"One carbon pool by folate";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"One carbon pool by folate" XP_037807142.1 8 Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-5628897 "Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Macroautophagy";"Neutrophil degranulation";"TP53 Regulates Metabolic Genes" XP_037806122.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_037815693.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_037828277.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037815748.1 2 Reactome: R-HSA-204174;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid" XP_037816352.1 3 Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508 "G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis" XP_037812087.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037822005.1 2 Reactome: R-HSA-4549349;Reactome: R-HSA-446193 "Defective ALG2 causes ALG2-CDG (CDG-1i)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_037820926.1 16 Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-8936459;Reactome: R-HSA-2559580;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-8986944;Reactome: R-HSA-426496;Reactome: R-HSA-9018519 "Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Oxidative Stress Induced Senescence";"Ca2+ pathway";"Oncogene Induced Senescence";"Transcriptional Regulation by MECP2";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression" XP_037811917.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037818978.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_037806559.1 4 Reactome: R-HSA-6782861;MetaCyc: PWY-7285;MetaCyc: PWY-6829;MetaCyc: PWY-7286 "Synthesis of wybutosine at G37 of tRNA(Phe)";"Methylwyosine biosynthesis";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis" XP_037816639.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-5663220 "Signaling by ROBO receptors";"RHO GTPases Activate Formins" XP_037813457.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" XP_037819623.1 13 MetaCyc: PWY-2161;MetaCyc: PWY-5497;KEGG: 00670+6.3.4.3;MetaCyc: PWY-6613;MetaCyc: PWY-1722;MetaCyc: PWY-5030;MetaCyc: PWY-2201;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;MetaCyc: PWY-3841;KEGG: 00720+6.3.4.3;Reactome: R-HSA-196757 "Folate polyglutamylation";"Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"L-histidine degradation III";"Folate transformations I";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines" XP_037809563.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037812224.1 22 MetaCyc: PWY-7592;MetaCyc: PWY-8041;MetaCyc: PWY-7606;MetaCyc: PWY-7053;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7727;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-5353;MetaCyc: PWY-7728;MetaCyc: PWY-7726;KEGG: 00062+4.2.1.134;MetaCyc: PWY-6958;Reactome: R-HSA-75876;MetaCyc: PWY-7049;MetaCyc: PWY-7601 "Arachidonate biosynthesis III (6-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid elongation";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_037810608.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037810861.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037821274.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037825366.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037821937.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_037811858.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037815969.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037820728.1 7 KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway" XP_037806287.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037806475.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037813723.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037812776.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_037809095.1 4 MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;Reactome: R-HSA-72731 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Recycling of eIF2:GDP" XP_037812089.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037816573.1 9 Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-191859;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-2151201 "RORA activates gene expression";"PPARA activates gene expression";"snRNP Assembly";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis" XP_037824765.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_037812782.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037811454.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037818167.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_037814301.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_037817731.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037815306.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037818394.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259 "Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism" XP_037824866.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037807872.1 9 MetaCyc: PWY-7385;MetaCyc: PWY-6118;MetaCyc: PWY-5667;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7902;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.8 "1,3-propanediol biosynthesis (engineered)";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism" XP_037825602.1 9 Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-73776 "HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape" XP_037821275.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037810749.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-1268020 "Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import" XP_037806830.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6798695 "COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation" XP_037824084.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037806024.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037820568.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037815692.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_037808955.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037819054.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037818339.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_037805830.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037807072.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_037821487.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037820406.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_037809969.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037811590.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037812864.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_037828688.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037827259.1 7 KEGG: 00550+2.7.8.13;Reactome: R-HSA-4549356;MetaCyc: PWY-6470;MetaCyc: PWY-6471;Reactome: R-HSA-446193;MetaCyc: PWY-5265;KEGG: 00510+2.7.8.15 "Peptidoglycan biosynthesis";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis II (staphylococci)";"N-Glycan biosynthesis" XP_037805550.1 12 Reactome: R-HSA-2122948;Reactome: R-HSA-9017802;Reactome: R-HSA-2979096;Reactome: R-HSA-3928665;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-1251985;Reactome: R-HSA-2894862;Reactome: R-HSA-193692;Reactome: R-HSA-977225;Reactome: R-HSA-2644606;Reactome: R-HSA-205043 "Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulated proteolysis of p75NTR";"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NRIF signals cell death from the nucleus" XP_037813712.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037827628.1 3 Reactome: R-HSA-8964208;KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1 "Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism" XP_037806626.1 8 Reactome: R-HSA-180024;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-442720;Reactome: R-HSA-983231 "DARPP-32 events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production" XP_037825919.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037818129.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_037812417.1 6 Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-8874081;Reactome: R-HSA-8948216;Reactome: R-HSA-3000171;Reactome: R-HSA-1442490 "Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"MET activates PTK2 signaling";"Collagen chain trimerization";"Non-integrin membrane-ECM interactions";"Collagen degradation" XP_037809233.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_037812222.1 4 MetaCyc: PWY-7250;Reactome: R-HSA-1362409;KEGG: 00730+2.8.1.7;Reactome: R-HSA-947581 "[2Fe-2S] iron-sulfur cluster biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Thiamine metabolism";"Molybdenum cofactor biosynthesis" XP_037824810.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_037821441.1 19 Reactome: R-HSA-5576892;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-9022692;Reactome: R-HSA-9609736;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-9617324 "Phase 0 - rapid depolarisation";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"Interferon gamma signaling";"HSF1-dependent transactivation";"Regulation of MECP2 expression and activity";"Assembly and cell surface presentation of NMDA receptors";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_037820269.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037824923.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_037809478.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037808468.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes" XP_037824103.1 4 KEGG: 00260+4.2.1.22;Reactome: R-HSA-1614603;MetaCyc: PWY-801;KEGG: 00270+4.2.1.22 "Glycine, serine and threonine metabolism";"Cysteine formation from homocysteine";"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism" XP_037807022.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037824200.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_037810318.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295 "COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation" XP_037814433.1 3 Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-191859 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"snRNP Assembly" XP_037814903.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_037828280.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_037806055.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_037821914.1 17 KEGG: 04658+3.1.3.16;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-167152;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-167158;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-75955 "Th1 and Th2 cell differentiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"T cell receptor signaling pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation" XP_037819950.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037805883.1 5 MetaCyc: PWY-6692;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7279;MetaCyc: PWY-3781;MetaCyc: PWY-7082 "Fe(II) oxidation";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"Ammonia oxidation IV (autotrophic ammonia oxidizers)" XP_037814836.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_037826019.1 8 MetaCyc: PWY-3581;KEGG: 00790+1.14.16.2;KEGG: 00350+1.14.16.2;MetaCyc: PWY-5049;MetaCyc: PWY-6133;Reactome: R-HSA-209905;MetaCyc: PWY-5394;KEGG: 00950+1.14.16.2 "(S)-reticuline biosynthesis I";"Folate biosynthesis";"Tyrosine metabolism";"Rosmarinic acid biosynthesis II";"(S)-reticuline biosynthesis II";"Catecholamine biosynthesis";"Betalamic acid biosynthesis";"Isoquinoline alkaloid biosynthesis" XP_037817960.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037815133.1 15 Reactome: R-HSA-5358747;Reactome: R-HSA-195253;Reactome: R-HSA-5467337;Reactome: R-HSA-5689896;Reactome: R-HSA-5358749;Reactome: R-HSA-5358751;Reactome: R-HSA-111465;Reactome: R-HSA-5339716;Reactome: R-HSA-5467333;Reactome: R-HSA-5358752;Reactome: R-HSA-3769402;Reactome: R-HSA-5467348;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-4641262 "S33 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding";"Ovarian tumor domain proteases";"S37 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"Misspliced GSK3beta mutants stabilize beta-catenin";"APC truncation mutants are not K63 polyubiquitinated";"T41 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"Truncations of AMER1 destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane" XP_037808037.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_037814868.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037806477.1 7 KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway" XP_037820071.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037823018.1 3 Reactome: R-HSA-947581;KEGG: 00790+2.8.1.9;MetaCyc: PWY-5963 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Thio-molybdenum cofactor biosynthesis" XP_037826918.1 10 Reactome: R-HSA-8875360;Reactome: R-HSA-9635644;Reactome: R-HSA-6807004;Reactome: R-HSA-917729;Reactome: R-HSA-5689880;Reactome: R-HSA-432720;Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-9636383 "InlB-mediated entry of Listeria monocytogenes into host cell";"Inhibition of membrane repair";"Negative regulation of MET activity";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Ub-specific processing proteases";"Lysosome Vesicle Biogenesis";"EGFR downregulation";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Prevention of phagosomal-lysosomal fusion" XP_037816868.1 5 Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400 "VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer" XP_037811626.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_037809973.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037828443.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_037808558.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_037817377.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037817922.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_037819407.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_037813504.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_037811750.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037806424.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956 "L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Peptide chain elongation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_037825662.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7802 "Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)" XP_037821921.1 5 Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_037815309.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037828860.1 8 Reactome: R-HSA-4641263;Reactome: R-HSA-4608870;Reactome: R-HSA-4086398;Reactome: R-HSA-5340588;Reactome: R-HSA-373080;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900 "Regulation of FZD by ubiquitination";"Asymmetric localization of PCP proteins";"Ca2+ pathway";"RNF mutants show enhanced WNT signaling and proliferation";"Class B/2 (Secretin family receptors)";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4" XP_037810324.1 12 Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436 "MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic" XP_037818569.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_037828687.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037809133.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037827863.1 3 Reactome: R-HSA-3108214;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394 "SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER" XP_037806141.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_037817477.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037805963.1 3 MetaCyc: PWY-7286;MetaCyc: PWY-7285;MetaCyc: PWY-6829 "7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis";"Trna methylation (yeast)" XP_037822817.1 8 Reactome: R-HSA-8866652;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6804757;Reactome: R-HSA-5689880;Reactome: R-HSA-6781827;Reactome: R-HSA-8948747;Reactome: R-HSA-6782135 "Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Regulation of TP53 Degradation";"Ub-specific processing proteases";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of PTEN localization";"Dual incision in TC-NER" XP_037808398.1 3 MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077 "Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen synthesis" XP_037817101.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037812053.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_037827877.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_037822908.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037817855.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037827612.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_037821126.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_037807087.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_037817674.1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814 "Collagen chain trimerization";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes" XP_037815845.1 11 Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-164378 "G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"G alpha (z) signalling events";"Purine metabolism";"Glucagon signaling in metabolic regulation";"PKA activation";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling" XP_037817823.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037805534.1 2 KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281 "Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_037806944.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_037812393.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037820417.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_037811302.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037808260.1 19 Reactome: R-HSA-8950505;Reactome: R-HSA-3928662;Reactome: R-HSA-5627123;Reactome: R-HSA-5687128;Reactome: R-HSA-114604;Reactome: R-HSA-5625970;Reactome: R-HSA-5663220;Reactome: R-HSA-418885;Reactome: R-HSA-428543;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-525793;Reactome: R-HSA-5626467;Reactome: R-HSA-194840;Reactome: R-HSA-2029482;Reactome: R-HSA-8964616;Reactome: R-HSA-983231;Reactome: R-HSA-389359;Reactome: R-HSA-182971 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"EPHB-mediated forward signaling";"RHO GTPases activate PAKs";"MAPK6/MAPK4 signaling";"GPVI-mediated activation cascade";"RHO GTPases activate KTN1";"RHO GTPases Activate Formins";"DCC mediated attractive signaling";"Inactivation of CDC42 and RAC1";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Myogenesis";"RHO GTPases activate IQGAPs";"Rho GTPase cycle";"Regulation of actin dynamics for phagocytic cup formation";"G beta:gamma signalling through CDC42";"Factors involved in megakaryocyte development and platelet production";"CD28 dependent Vav1 pathway";"EGFR downregulation" XP_037808791.1 52 Reactome: R-HSA-75955;Reactome: R-HSA-427413;Reactome: R-HSA-9018519;Reactome: R-HSA-5601884;Reactome: R-HSA-167200;Reactome: R-HSA-6781823;Reactome: R-HSA-75953;Reactome: R-HSA-73772;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-72203;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-8851708;Reactome: R-HSA-203927;Reactome: R-HSA-749476;Reactome: R-HSA-113418;Reactome: R-HSA-6782135;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-72165;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-6796648;Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-76061;Reactome: R-HSA-168325;Reactome: R-HSA-72163;Reactome: R-HSA-167243;Reactome: R-HSA-5578749;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-167152;Reactome: R-HSA-73980;Reactome: R-HSA-6803529;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-5617472;Reactome: R-HSA-6781827;Reactome: R-HSA-167160 "RNA Polymerase II Transcription Elongation";"NoRC negatively regulates rRNA expression";"Estrogen-dependent gene expression";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"Signaling by FGFR2 IIIa TM";"MicroRNA (miRNA) biogenesis";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of the Early Elongation Complex";"Dual incision in TC-NER";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Splicing - Minor Pathway";"mRNA Capping";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Viral Messenger RNA Synthesis";"mRNA Splicing - Major Pathway";"Tat-mediated HIV elongation arrest and recovery";"Transcriptional regulation by small RNAs";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase III Transcription Termination";"FGFR2 alternative splicing";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection" XP_037806348.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876 "(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs" XP_037818845.1 7 KEGG: 00270+6.3.2.2;Reactome: R-HSA-174403;MetaCyc: PWY-8043;MetaCyc: PWY-7255;Reactome: R-HSA-5578999;KEGG: 00480+6.3.2.2;MetaCyc: PWY-6840 "Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Ergothioneine biosynthesis I (bacteria)";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione metabolism";"Homoglutathione biosynthesis" XP_037820015.1 10 Reactome: R-HSA-4719360;MetaCyc: PWY-7922;Reactome: R-HSA-4719377;Reactome: R-HSA-913709;KEGG: 00510+2.4.1.83;MetaCyc: PWY-7661;MetaCyc: PWY-7921;Reactome: R-HSA-4717374;MetaCyc: PWY-7979;Reactome: R-HSA-162699 "Defective DPM3 causes DPM3-CDG (CDG-1o)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"O-linked glycosylation of mucins";"N-Glycan biosynthesis";"Protein N-glycosylation (Haloferax volcanii)";"Protein O-mannosylation I (yeast)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Protein O-mannosylation III (mammals, core M3)";"Synthesis of dolichyl-phosphate mannose" XP_037822179.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037811395.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" XP_037822970.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_037812170.1 3 KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894 "Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation" XP_037824875.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_037819765.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_037825427.1 1 Reactome: R-HSA-5632928 "Defective Mismatch Repair Associated With MSH2" XP_037815679.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_037817041.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037825866.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_037812375.1 2 Reactome: R-HSA-166665;Reactome: R-HSA-977606 "Terminal pathway of complement";"Regulation of Complement cascade" XP_037812970.1 6 KEGG: 04070+3.1.3.36;Reactome: R-HSA-194840;MetaCyc: PWY-6368;Reactome: R-HSA-1855204;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855183 "Phosphatidylinositol signaling system";"Rho GTPase cycle";"3-phosphoinositide degradation";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol" XP_037806145.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037813519.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_037812800.1 19 MetaCyc: PWY-561;KEGG: 00720+1.1.1.37;KEGG: 00680+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-5913;MetaCyc: PWY-8086;MetaCyc: PWY-7383;MetaCyc: PWY-7115;MetaCyc: PWY-5392;Reactome: R-HSA-71403;KEGG: 00270+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00020+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-6728;Reactome: R-HSA-70263;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5690 "Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Methane metabolism";"Pyruvate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"Cysteine and methionine metabolism";"Formaldehyde assimilation I (serine pathway)";"Citrate cycle (TCA cycle)";"Carbon fixation in photosynthetic organisms";"Methylaspartate cycle";"Gluconeogenesis";"Glyoxylate and dicarboxylate metabolism";"TCA cycle II (plants and fungi)" XP_037818359.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037810696.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_037823739.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_037821691.1 12 MetaCyc: PWY-5870;KEGG: 00130+2.5.1.39;Reactome: R-HSA-1268020;MetaCyc: PWY-5857;MetaCyc: PWY-6708;MetaCyc: PWY-5873;MetaCyc: PWY-6978;MetaCyc: PWY-5856;MetaCyc: PWY-5872;MetaCyc: PWY-5871;MetaCyc: PWY-5855;Reactome: R-HSA-2142789 "Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Mitochondrial protein import";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis" XP_037828452.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-1663150 "Glycosphingolipid metabolism";"The activation of arylsulfatases" XP_037810328.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690 "COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Aggrephagy";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events" XP_037813307.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_037824284.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_037828607.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037820255.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037813616.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_037806133.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_037814417.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_037817035.1 2 MetaCyc: PWY-6938;Reactome: R-HSA-430039 "NADH repair";"mRNA decay by 5' to 3' exoribonuclease" XP_037825944.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_037806996.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037826418.1 14 MetaCyc: PWY-5078;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5076;KEGG: 00280+2.6.1.42;Reactome: R-HSA-70895;MetaCyc: PWY-5103;KEGG: 00966+2.6.1.42;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5101;MetaCyc: PWY-5104;MetaCyc: PWY-5108;MetaCyc: PWY-7767;MetaCyc: PWY-5057;KEGG: 00290+2.6.1.42 "L-isoleucine degradation II";"Cysteine and methionine metabolism";"L-leucine degradation III";"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"L-isoleucine biosynthesis III";"Glucosinolate biosynthesis";"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis II";"L-isoleucine biosynthesis IV";"L-isoleucine biosynthesis V";"L-leucine degradation IV (Stickland reaction)";"L-valine degradation II";"Valine, leucine and isoleucine biosynthesis" XP_037806945.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_037813610.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_037823512.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970 "MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1" XP_037823743.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_037812983.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037824223.1 8 Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-8866652;Reactome: R-HSA-8948747;Reactome: R-HSA-6782135;Reactome: R-HSA-6804757;Reactome: R-HSA-5689880;Reactome: R-HSA-6781827 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of PTEN localization";"Dual incision in TC-NER";"Regulation of TP53 Degradation";"Ub-specific processing proteases";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" XP_037810585.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037808075.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_037814592.1 5 Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-110328;Reactome: R-HSA-5221030;Reactome: R-HSA-110357 "Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1" XP_037823798.1 9 Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167172 "RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Transcription of the HIV genome" XP_037826514.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_037819482.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380270 "Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_037806976.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037825867.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_037828201.1 179 Reactome: R-HSA-6782210;Reactome: R-HSA-975144;Reactome: R-HSA-5658442;Reactome: R-HSA-209543;Reactome: R-HSA-937041;Reactome: R-HSA-174048;Reactome: R-HSA-5656121;Reactome: R-HSA-8939902;Reactome: R-HSA-2644606;Reactome: R-HSA-3134975;Reactome: R-HSA-8948747;Reactome: R-HSA-445989;Reactome: R-HSA-3322077;Reactome: R-HSA-5362768;Reactome: R-HSA-5654732;Reactome: R-HSA-202424;Reactome: R-HSA-72706;Reactome: R-HSA-182971;Reactome: R-HSA-5654726;Reactome: R-HSA-2173788;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-72764;Reactome: R-HSA-174113;Reactome: R-HSA-5357905;Reactome: R-HSA-5676590;Reactome: R-HSA-5693565;Reactome: R-HSA-5689877;Reactome: R-HSA-5358346;Reactome: R-HSA-2122947;Reactome: R-HSA-5610785;Reactome: R-HSA-174490;Reactome: R-HSA-3785653;Reactome: R-HSA-9633012;Reactome: R-HSA-209560;Reactome: R-HSA-174184;Reactome: R-HSA-975163;Reactome: R-HSA-5696395;Reactome: R-HSA-400253;Reactome: R-HSA-4641258;Reactome: R-HSA-532668;Reactome: R-HSA-5632684;Reactome: R-HSA-6782135;Reactome: R-HSA-6807004;Reactome: R-HSA-168927;Reactome: R-HSA-175474;Reactome: R-HSA-901032;Reactome: R-HSA-9645460;Reactome: R-HSA-72689;Reactome: R-HSA-69601;Reactome: R-HSA-975957;Reactome: R-HSA-75815;Reactome: R-HSA-5675482;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-977225;Reactome: R-HSA-5696397;Reactome: R-HSA-6783310;Reactome: R-HSA-9013973;Reactome: R-HSA-110314;Reactome: R-HSA-9014325;Reactome: R-HSA-5687128;Reactome: R-HSA-8866654;Reactome: R-HSA-2173791;Reactome: R-HSA-9636383;Reactome: R-HSA-937072;Reactome: R-HSA-205043;Reactome: R-HSA-6791226;Reactome: R-HSA-110312;Reactome: R-HSA-2122948;Reactome: R-HSA-1236974;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-2565942;Reactome: R-HSA-2979096;Reactome: R-HSA-174084;Reactome: R-HSA-1169408;Reactome: R-HSA-5696400;Reactome: R-HSA-211733;Reactome: R-HSA-162588;Reactome: R-HSA-8856828;Reactome: R-HSA-5357956;Reactome: R-HSA-192823;Reactome: R-HSA-2672351;Reactome: R-HSA-8856825;Reactome: R-HSA-349425;Reactome: R-HSA-5693607;Reactome: R-HSA-6804760;Reactome: R-HSA-2691232;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-5684264;Reactome: R-HSA-3769402;Reactome: R-HSA-180585;Reactome: R-HSA-5654727;Reactome: R-HSA-2894862;Reactome: R-HSA-9646399;Reactome: R-HSA-975110;Reactome: R-HSA-917937;Reactome: R-HSA-9613829;Reactome: R-HSA-936964;Reactome: R-HSA-6804757;Reactome: R-HSA-5696394;Reactome: R-HSA-69017;Reactome: R-HSA-8863795;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-912631;Reactome: R-HSA-8951664;Reactome: R-HSA-1295596;Reactome: R-HSA-4608870;Reactome: R-HSA-2559580;Reactome: R-HSA-2559585;Reactome: R-HSA-8849469;Reactome: R-HSA-201681;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-2408557;Reactome: R-HSA-5610783;Reactome: R-HSA-110320;Reactome: R-HSA-2173795;Reactome: R-HSA-9615710;Reactome: R-HSA-5655862;Reactome: R-HSA-6781823;Reactome: R-HSA-8939236;Reactome: R-HSA-1236382;Reactome: R-HSA-168638;Reactome: R-HSA-5689603;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-174154;Reactome: R-HSA-9013507;Reactome: R-HSA-8866652;Reactome: R-HSA-4641257;Reactome: R-HSA-9637628;Reactome: R-HSA-5675221;Reactome: R-HSA-5689880;Reactome: R-HSA-6781827;Reactome: R-HSA-450321;Reactome: R-HSA-2173796;Reactome: R-HSA-936440;Reactome: R-HSA-168928;Reactome: R-HSA-8875360;Reactome: R-HSA-450302;Reactome: R-HSA-195253;Reactome: R-HSA-917729;Reactome: R-HSA-4641263;Reactome: R-HSA-156827;Reactome: R-HSA-5654733;Reactome: R-HSA-68949;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5689901;Reactome: R-HSA-5205685;Reactome: R-HSA-937042;Reactome: R-HSA-1358803;Reactome: R-HSA-1799339;Reactome: R-HSA-69231;Reactome: R-HSA-382556;Reactome: R-HSA-8876493;Reactome: R-HSA-156902;Reactome: R-HSA-6804756;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-9033241;Reactome: R-HSA-937039;Reactome: R-HSA-8854050;Reactome: R-HSA-69541;Reactome: R-HSA-1253288;Reactome: R-HSA-5689896 "Gap-filling DNA repair synthesis and ligation in TC-NER";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Regulation of RAS by GAPs";"p75NTR recruits signalling complexes";"IKK complex recruitment mediated by RIP1";"APC/C:Cdc20 mediated degradation of Cyclin B";"Translesion synthesis by POLI";"Regulation of RUNX2 expression and activity";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of innate immune responses to cytosolic DNA";"Regulation of PTEN localization";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Glycogen synthesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Negative regulation of FGFR3 signaling";"Downstream TCR signaling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"EGFR downregulation";"Negative regulation of FGFR1 signaling";"Downregulation of TGF-beta receptor signaling";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Eukaryotic Translation Termination";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of TNFR1 signaling";"NIK-->noncanonical NF-kB signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Josephin domain DUBs";"Hedgehog ligand biogenesis";"NOTCH1 Intracellular Domain Regulates Transcription";"GLI3 is processed to GLI3R by the proteasome";"Membrane binding and targetting of GAG proteins";"Myoclonic epilepsy of Lafora";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"NF-kB is activated and signals survival";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Formation of Incision Complex in GG-NER";"Circadian Clock";"Degradation of DVL";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Hedgehog 'on' state";"Dual incision in TC-NER";"Negative regulation of MET activity";"TICAM1, RIP1-mediated IKK complex recruitment";"Assembly Of The HIV Virion";"ER Quality Control Compartment (ERQC)";"Alpha-protein kinase 1 signaling pathway";"Formation of a pool of free 40S subunits";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of necroptotic cell death";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Amyloid fiber formation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Fanconi Anemia Pathway";"TICAM1-dependent activation of IRF3/IRF7";"Recognition of DNA damage by PCNA-containing replication complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"MAPK6/MAPK4 signaling";"E3 ubiquitin ligases ubiquitinate target proteins";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Prevention of phagosomal-lysosomal fusion";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"NRIF signals cell death from the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translesion synthesis by REV1";"Activated NOTCH1 Transmits Signal to the Nucleus";"ER-Phagosome pathway";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of PLK1 Activity at G2/M Transition";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Autodegradation of Cdh1 by Cdh1:APC/C";"ISG15 antiviral mechanism";"Dual Incision in GG-NER";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Budding and maturation of HIV virion";"Clathrin-mediated endocytosis";"TNFR1-induced NFkappaB signaling pathway";"Viral mRNA Translation";"Stimuli-sensing channels";"Cargo recognition for clathrin-mediated endocytosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Methylation";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Deactivation of the beta-catenin transactivating complex";"Vif-mediated degradation of APOBEC3G";"Negative regulation of FGFR2 signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Aggrephagy";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Iron uptake and transport";"Chaperone Mediated Autophagy";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Regulation of TP53 Degradation";"DNA Damage Recognition in GG-NER";"CDK-mediated phosphorylation and removal of Cdc6";"Downregulation of ERBB2 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of signaling by CBL";"Neddylation";"Spry regulation of FGF signaling";"Asymmetric localization of PCP proteins";"Oxidative Stress Induced Senescence";"Oncogene Induced Senescence";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"TCF dependent signaling in response to WNT";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Selenocysteine synthesis";"Degradation of GLI2 by the proteasome";"Translesion Synthesis by POLH";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Late endosomal microautophagy";"Translesion synthesis by POLK";"Formation of TC-NER Pre-Incision Complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"NOD1/2 Signaling Pathway";"UCH proteinases";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"APC/C:Cdc20 mediated degradation of Securin";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Degradation of AXIN";"Modulation by Mtb of host immune system";"Negative regulation of MAPK pathway";"Ub-specific processing proteases";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Negative regulators of DDX58/IFIH1 signaling";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"InlB-mediated entry of Listeria monocytogenes into host cell";"activated TAK1 mediates p38 MAPK activation";"Degradation of beta-catenin by the destruction complex";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Regulation of FZD by ubiquitination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Negative regulation of FGFR4 signaling";"Orc1 removal from chromatin";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Metalloprotease DUBs";"Pink/Parkin Mediated Mitophagy";"IRAK2 mediated activation of TAK1 complex";"Downregulation of ERBB2:ERBB3 signaling";"SRP-dependent cotranslational protein targeting to membrane";"Cyclin D associated events in G1";"ABC-family proteins mediated transport";"InlA-mediated entry of Listeria monocytogenes into host cells";"Peptide chain elongation";"Regulation of TP53 Activity through Phosphorylation";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"Peroxisomal protein import";"IRAK1 recruits IKK complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Stabilization of p53";"Downregulation of ERBB4 signaling";"Ovarian tumor domain proteases" XP_037819804.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_037819271.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_037807876.1 9 MetaCyc: PWY-7902;MetaCyc: PWY-5667;KEGG: 00564+1.1.1.94;MetaCyc: PWY-6118;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-5981 "Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III" XP_037808920.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037827667.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037809121.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695 "Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation" XP_037805984.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_037812520.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_037817152.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037815176.1 24 KEGG: 05163+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-1257604;Reactome: R-HSA-165158;Reactome: R-HSA-5625740;Reactome: R-HSA-9634635;Reactome: R-HSA-392451;KEGG: 04714+2.7.11.1;Reactome: R-HSA-202424;Reactome: R-HSA-444257;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;KEGG: 04150+2.7.11.1;Reactome: R-HSA-114604;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-2730905;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-2871837;Reactome: R-HSA-5218920 "Human cytomegalovirus infection";"CLEC7A (Dectin-1) signaling";"PIP3 activates AKT signaling";"Activation of AKT2";"RHO GTPases activate PKNs";"Estrogen-stimulated signaling through PRKCZ";"G beta:gamma signalling through PI3Kgamma";"Thermogenesis";"Downstream TCR signaling";"RSK activation";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"mTOR signaling pathway";"GPVI-mediated activation cascade";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"VEGFR2 mediated cell proliferation";"Role of LAT2/NTAL/LAB on calcium mobilization";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Integrin signaling";"FCERI mediated NF-kB activation";"VEGFR2 mediated vascular permeability" XP_037823063.1 3 Reactome: R-HSA-8854214;Reactome: R-HSA-8875656;Reactome: R-HSA-8856828 "TBC/RABGAPs";"MET receptor recycling";"Clathrin-mediated endocytosis" XP_037815613.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_037819719.1 14 MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-8055;MetaCyc: PWY-8053;KEGG: 00565+3.1.3.4;Reactome: R-HSA-1483191;Reactome: R-HSA-4419969;MetaCyc: PWY-8052;Reactome: R-HSA-75109;Reactome: R-HSA-1483213;MetaCyc: PWY-8051;KEGG: 00561+3.1.3.4;KEGG: 00600+3.1.3.4;KEGG: 00564+3.1.3.4 "Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Ether lipid metabolism";"Synthesis of PC";"Depolymerisation of the Nuclear Lamina";"2-arachidonoylglycerol biosynthesis";"Triglyceride biosynthesis";"Synthesis of PE";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Sphingolipid metabolism";"Glycerophospholipid metabolism" XP_037828432.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_037820630.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037817297.1 4 Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437 "UCH proteinases";"HATs acetylate histones";"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation" XP_037820569.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037809044.1 4 Reactome: R-HSA-912631;Reactome: R-HSA-8875656;Reactome: R-HSA-186763;Reactome: R-HSA-8875555 "Regulation of signaling by CBL";"MET receptor recycling";"Downstream signal transduction";"MET activates RAP1 and RAC1" XP_037809587.1 3 Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-5689877 "Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"Josephin domain DUBs" XP_037809088.1 6 MetaCyc: PWY-7920;Reactome: R-HSA-975578;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143 "Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis" XP_037806776.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection" XP_037815167.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_037828634.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_037818984.1 4 Reactome: R-HSA-2408557;KEGG: 00970+6.1.1.11;Reactome: R-HSA-379716;MetaCyc: PWY-6281 "Selenocysteine synthesis";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_037816146.1 2 Reactome: R-HSA-2022377;Reactome: R-HSA-6798695 "Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation" XP_037815745.1 2 Reactome: R-HSA-5362517;Reactome: R-HSA-204174 "Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_037813054.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037808325.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037811629.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_037825159.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_037814128.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_037824991.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_037818727.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037825363.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037823123.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037806759.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection" XP_037828217.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_037807927.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_037812418.1 6 Reactome: R-HSA-1650814;Reactome: R-HSA-8874081;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-3000171;Reactome: R-HSA-8948216 "Collagen biosynthesis and modifying enzymes";"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Non-integrin membrane-ECM interactions";"Collagen chain trimerization" XP_037823434.1 3 KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317 "Galactose metabolism";"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)" XP_037818344.1 18 Reactome: R-HSA-1483166;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;MetaCyc: PWY-7783;MetaCyc: PWY-7416;Reactome: R-HSA-1482801;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-8051 "Synthesis of PA";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Acyl chain remodelling of PC";"Anandamide biosynthesis I" XP_037813505.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_037810612.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_037810678.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037809381.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037824490.1 3 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843 "Pentose phosphate pathway";"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis" XP_037817403.1 8 Reactome: R-HSA-1222556;Reactome: R-HSA-167590;Reactome: R-HSA-917977;Reactome: R-HSA-182218;Reactome: R-HSA-77387;Reactome: R-HSA-9636467;Reactome: R-HSA-983712;Reactome: R-HSA-9639288 "ROS and RNS production in phagocytes";"Nef Mediated CD4 Down-regulation";"Transferrin endocytosis and recycling";"Nef Mediated CD8 Down-regulation";"Insulin receptor recycling";"Blockage of phagosome acidification";"Ion channel transport";"Amino acids regulate mTORC1" XP_037809575.1 27 Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-4615885 "SUMOylation of SUMOylation proteins";"snRNP Assembly";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins" XP_037818193.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" YP_001425543.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_037813817.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037817252.1 3 Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110357 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1" XP_037820520.1 14 MetaCyc: PWY-7417;Reactome: R-HSA-975634;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7416;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4 "Phospholipid remodeling (phosphatidate, yeast)";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Ether lipid metabolism" XP_037824041.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_037806294.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037823889.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-5576893 "NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase" XP_037818128.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037813891.1 13 KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.23;Reactome: R-HSA-1660662;Reactome: R-HSA-2206308;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-4341670;Reactome: R-HSA-4085001 "Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Keratan sulfate degradation";"Other glycan degradation";"Glycosphingolipid metabolism";"MPS IV - Morquio syndrome B";"Galactose metabolism";"HS-GAG degradation";"Defective NEU1 causes sialidosis";"Sialic acid metabolism" XP_037825968.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_037819459.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling" XP_037827245.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_037809535.1 24 Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-9648025;Reactome: R-HSA-190840 "Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Aggrephagy";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Gap junction assembly";"Cilium Assembly";"HCMV Early Events";"Recycling pathway of L1";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane" XP_037812157.1 3 Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691 "Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_037825941.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_037828787.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037814537.1 14 MetaCyc: PWY-3841;KEGG: 00630+2.1.2.1;MetaCyc: PWY-3661-1;KEGG: 00460+2.1.2.1;KEGG: 00680+2.1.2.1;Reactome: R-HSA-196757;MetaCyc: PWY-181;KEGG: 00670+2.1.2.1;MetaCyc: PWY-3661;MetaCyc: PWY-2201;KEGG: 00260+2.1.2.1;MetaCyc: PWY-5497;MetaCyc: PWY-2161;MetaCyc: PWY-1622 "Folate transformations II (plants)";"Glyoxylate and dicarboxylate metabolism";"Glycine betaine degradation II (mammalian)";"Cyanoamino acid metabolism";"Methane metabolism";"Metabolism of folate and pterines";"Photorespiration ";"One carbon pool by folate";"Glycine betaine degradation I";"Folate transformations I";"Glycine, serine and threonine metabolism";"Purine nucleobases degradation II (anaerobic)";"Folate polyglutamylation";"Formaldehyde assimilation I (serine pathway)" XP_037812384.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037827006.1 4 KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2 "Lysine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism" XP_037815724.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_037820229.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037815830.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_037822545.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_037817090.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037826835.1 18 MetaCyc: PWY-7197;MetaCyc: PWY-7187;MetaCyc: PWY-7176;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7224;MetaCyc: PWY-7222;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7226;MetaCyc: PWY-7184;MetaCyc: PWY-7198;MetaCyc: PWY-7205;MetaCyc: PWY-7220;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7221 "Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis" XP_037819492.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_037819534.1 17 Reactome: R-HSA-6796648;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-1433557;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;KEGG: 05163+2.7.11.1;Reactome: R-HSA-69601;KEGG: 04151+2.7.11.1;Reactome: R-HSA-75035;KEGG: 05170+2.7.11.1;Reactome: R-HSA-69473;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-8953750 "TP53 Regulates Transcription of DNA Repair Genes";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"Signaling by SCF-KIT";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Human cytomegalovirus infection";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"PI3K-Akt signaling pathway";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Human immunodeficiency virus 1 infection";"G2/M DNA damage checkpoint";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Transcriptional Regulation by E2F6" XP_037810811.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_037828823.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037819824.1 6 Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788 "Circadian Clock";"T cell receptor signaling pathway";"Triglyceride catabolism";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling" XP_037806174.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_037819705.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_037810087.1 4 MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822 "Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)" XP_037819792.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_037818280.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037815942.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_037819301.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037807623.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_037815452.1 13 Reactome: R-HSA-4086398;Reactome: R-HSA-1489509;Reactome: R-HSA-5578775;Reactome: R-HSA-5607763;Reactome: R-HSA-114508;Reactome: R-HSA-2029485;Reactome: R-HSA-112043;Reactome: R-HSA-139853;Reactome: R-HSA-422356;Reactome: R-HSA-5218921;Reactome: R-HSA-983695;Reactome: R-HSA-2871809;Reactome: R-HSA-381676 "Ca2+ pathway";"DAG and IP3 signaling";"Ion homeostasis";"CLEC7A (Dectin-1) induces NFAT activation";"Effects of PIP2 hydrolysis";"Role of phospholipids in phagocytosis";"PLC beta mediated events";"Elevation of cytosolic Ca2+ levels";"Regulation of insulin secretion";"VEGFR2 mediated cell proliferation";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FCERI mediated Ca+2 mobilization";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion" XP_037816819.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-6791226 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Viral mRNA Translation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037807274.1 2 KEGG: 00970+6.1.1.7;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_037824594.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037813824.1 33 KEGG: 00982+1.1.1.1;MetaCyc: PWY-6342;MetaCyc: PWY-3162;KEGG: 00830+1.1.1.1;MetaCyc: PWY-7013;KEGG: 00071+1.1.1.1;MetaCyc: PWY-5076;KEGG: 00626+1.1.1.1;Reactome: R-HSA-71384;KEGG: 00350+1.1.1.1;MetaCyc: PWY-6871;MetaCyc: PWY-5057;MetaCyc: PWY-6587;MetaCyc: PWY-7118;MetaCyc: PWY-1801;KEGG: 00010+1.1.1.1;MetaCyc: PWY-5078;KEGG: 00592+1.1.1.1;MetaCyc: PWY-7798;MetaCyc: PWY-6802;MetaCyc: PWY-5480;MetaCyc: PWY-5082;KEGG: 00680+1.1.1.284;MetaCyc: PWY-5751;MetaCyc: PWY-5079;MetaCyc: PWY-6313;KEGG: 00260+1.1.1.1;MetaCyc: PWY-7111;MetaCyc: PWY-6333;KEGG: 00980+1.1.1.1;KEGG: 00625+1.1.1.1;MetaCyc: PWY-5486;MetaCyc: PWY-7396 "Drug metabolism - cytochrome P450";"Noradrenaline and adrenaline degradation";"L-tryptophan degradation V (side chain pathway)";"Retinol metabolism";"(S)-propane-1,2-diol degradation";"Fatty acid degradation";"L-leucine degradation III";"Naphthalene degradation";"Ethanol oxidation";"Tyrosine metabolism";"3-methylbutanol biosynthesis (engineered)";"L-valine degradation II";"Pyruvate fermentation to ethanol III";"Chitin degradation to ethanol";"Formaldehyde oxidation II (glutathione-dependent)";"Glycolysis / Gluconeogenesis";"L-isoleucine degradation II";"alpha-Linolenic acid metabolism";"Protein S-nitrosylation and denitrosylation";"Salidroside biosynthesis";"Pyruvate fermentation to ethanol I";"L-methionine degradation III";"Methane metabolism";"Phenylethanol biosynthesis";"L-phenylalanine degradation III";"Serotonin degradation";"Glycine, serine and threonine metabolism";"Pyruvate fermentation to isobutanol (engineered)";"Acetaldehyde biosynthesis I";"Metabolism of xenobiotics by cytochrome P450";"Chloroalkane and chloroalkene degradation";"Pyruvate fermentation to ethanol II";"Butanol and isobutanol biosynthesis (engineered)" XP_037813509.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_037812068.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_037817295.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_037811542.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_037821702.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037820052.1 5 Reactome: R-HSA-446210;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749 "Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I" XP_037826117.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037812551.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_037824838.1 7 KEGG: 00051+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00680+3.1.3.11;KEGG: 00010+3.1.3.11;KEGG: 00030+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00710+3.1.3.11 "Fructose and mannose metabolism";"Gluconeogenesis";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms" XP_037808228.1 27 Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-9610379 "SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events" XP_037823930.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037825647.1 10 Reactome: R-HSA-5607764;Reactome: R-HSA-2565942;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-5684264;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761 "CLEC7A (Dectin-1) signaling";"Regulation of PLK1 Activity at G2/M Transition";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling" XP_037812435.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037813107.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037826500.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226 "Selenocysteine synthesis";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037825409.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes" XP_037812061.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_037815443.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037824310.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037813124.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037821102.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037807288.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_037826023.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037826642.1 6 Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_037827670.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037814852.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-1358803;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination" XP_037815321.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_037823414.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037816433.1 15 MetaCyc: PWY-6142;MetaCyc: PWY-6901;KEGG: 00010+2.7.1.40;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-5723;MetaCyc: PWY-8004;MetaCyc: PWY-7383;Reactome: R-HSA-70171;MetaCyc: PWY-2221;MetaCyc: PWY-6886;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-7003 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Purine metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"Entner-Doudoroff pathway I";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"1-butanol autotrophic biosynthesis (engineered)";"Pyruvate metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol" XP_037814435.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_037814345.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_037828603.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037810357.1 14 Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-5620924;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-1632852;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497 "Separation of Sister Chromatids";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Intraflagellar transport";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Macroautophagy";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_037813674.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156827 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_037807626.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_037821585.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037806165.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_037827244.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72702 "Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_037822601.1 5 Reactome: R-HSA-209560;Reactome: R-HSA-9020702;Reactome: R-HSA-5205685;Reactome: R-HSA-205043;Reactome: R-HSA-209543 "NF-kB is activated and signals survival";"Interleukin-1 signaling";"Pink/Parkin Mediated Mitophagy";"NRIF signals cell death from the nucleus";"p75NTR recruits signalling complexes" XP_037817727.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037809186.1 1 Reactome: R-HSA-2467813 "Separation of Sister Chromatids" XP_037821070.1 6 Reactome: R-HSA-163560;MetaCyc: PWY-6952;KEGG: 00564+1.1.5.3;Reactome: R-HSA-1483166;MetaCyc: PWY-4261;MetaCyc: PWY-6118 "Triglyceride catabolism";"Glycerophosphodiester degradation";"Glycerophospholipid metabolism";"Synthesis of PA";"Glycerol degradation I";"Glycerol-3-phosphate shuttle" XP_037827159.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037810008.1 13 Reactome: R-HSA-419037;Reactome: R-HSA-1442490;Reactome: R-HSA-186797;Reactome: R-HSA-8948216;Reactome: R-HSA-3000171;Reactome: R-HSA-2214320;Reactome: R-HSA-3000178;Reactome: R-HSA-2022090;Reactome: R-HSA-216083;Reactome: R-HSA-1474244;Reactome: R-HSA-2243919;Reactome: R-HSA-3000157;Reactome: R-HSA-1650814 "NCAM1 interactions";"Collagen degradation";"Signaling by PDGF";"Collagen chain trimerization";"Non-integrin membrane-ECM interactions";"Anchoring fibril formation";"ECM proteoglycans";"Assembly of collagen fibrils and other multimeric structures";"Integrin cell surface interactions";"Extracellular matrix organization";"Crosslinking of collagen fibrils";"Laminin interactions";"Collagen biosynthesis and modifying enzymes" XP_037806680.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_037828525.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037822242.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_037820695.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037807383.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037810459.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_037825361.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037820160.1 4 Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108 "Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis" XP_037823436.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_037809735.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation" XP_037827744.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037824491.1 3 KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1 "Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway" XP_037823794.1 9 Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110331;Reactome: R-HSA-9608287;Reactome: R-HSA-110330;Reactome: R-HSA-9608290;Reactome: R-HSA-9630221;Reactome: R-HSA-9630222 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged purine";"Defective MUTYH substrate binding";"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective MUTYH substrate processing";"Defective NTHL1 substrate processing";"Defective NTHL1 substrate binding" XP_037822541.1 15 Reactome: R-HSA-389357;Reactome: R-HSA-2219530;Reactome: R-HSA-9009391;Reactome: R-HSA-912526;Reactome: R-HSA-1433557;Reactome: R-HSA-114604;Reactome: R-HSA-512988;Reactome: R-HSA-1257604;Reactome: R-HSA-416476;Reactome: R-HSA-912631;Reactome: R-HSA-8853659;Reactome: R-HSA-6811558;Reactome: R-HSA-388841;Reactome: R-HSA-1660499;Reactome: R-HSA-1266695 "CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Extra-nuclear estrogen signaling";"Interleukin receptor SHC signaling";"Signaling by SCF-KIT";"GPVI-mediated activation cascade";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"PIP3 activates AKT signaling";"G alpha (q) signalling events";"Regulation of signaling by CBL";"RET signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Costimulation by the CD28 family";"Synthesis of PIPs at the plasma membrane";"Interleukin-7 signaling" XP_037810136.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_037805515.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037828438.1 9 Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-69166 "Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"G1/S-Specific Transcription";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate" XP_037814881.1 3 Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import" XP_037807057.1 1 Reactome: R-HSA-189451 "Heme biosynthesis" XP_037817315.1 4 Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;MetaCyc: PWY-7221 "Abacavir metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis" XP_037818633.1 56 Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-5362768;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-5658442 "G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"UCH proteinases";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs" XP_037823774.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037824910.1 7 Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-165159 "Macroautophagy";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling" XP_037817185.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037808683.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037826992.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_037821936.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_037825890.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_037821375.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037825860.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956 "L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_037824601.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037808420.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_037812733.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_037821817.1 3 KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807;Reactome: R-HSA-6798695 "Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation" XP_037806705.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037806337.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7601;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619 "Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Juniperonate biosynthesis" XP_037813622.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_037818994.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037812762.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_037808321.1 3 Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395 "Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER" XP_037826596.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_037817335.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_037818081.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037805224.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_037824641.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72764 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Peptide chain elongation";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination" XP_037812044.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_037824515.1 5 Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-201722;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Transcription Elongation" XP_037814107.1 12 KEGG: 00051+4.1.2.13;KEGG: 00030+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00010+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00710+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-1861;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70171 "Fructose and mannose metabolism";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Methane metabolism";"Glycolysis" XP_037814052.1 19 Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-3214858;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-8876725;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72702 "Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RMTs methylate histone arginines";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Protein methylation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Peptide chain elongation";"Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition" XP_037816516.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_037805487.1 3 Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646 "Defective ACY1 causes encephalopathy";"Arginine biosynthesis";"Aflatoxin activation and detoxification" XP_037812425.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_037806254.1 8 Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-9609690;Reactome: R-HSA-8953750;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-4551638;Reactome: R-HSA-212300 "Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"HCMV Early Events";"Transcriptional Regulation by E2F6";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA" XP_037820908.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037825525.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037814420.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_037806443.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037826749.1 6 KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23 "Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Sphingolipid metabolism" XP_037809618.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037810195.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037811422.1 6 MetaCyc: PWY-8004;KEGG: 00260+5.4.2.11;MetaCyc: PWY-1622;KEGG: 00680+5.4.2.11;MetaCyc: PWY-5484;KEGG: 00010+5.4.2.11 "Entner-Doudoroff pathway I";"Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis" XP_037819421.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_037822427.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I" XP_037817363.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037819244.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037815308.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037826262.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_037819281.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_037821628.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037828099.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_037822890.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037818804.1 14 Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-2022377;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975956 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Metabolism of Angiotensinogen to Angiotensins";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_037819817.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689 "Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" XP_037817986.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_037824499.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037814226.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_037806436.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_037807500.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037812050.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_037807611.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_037828153.1 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" XP_037819036.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_037814263.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037827045.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" XP_037825142.1 5 MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism" XP_037818522.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037817039.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037817046.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037805817.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-3214847 "Ub-specific processing proteases";"HATs acetylate histones" XP_037811421.1 6 KEGG: 00680+5.4.2.11;MetaCyc: PWY-1622;KEGG: 00260+5.4.2.11;MetaCyc: PWY-8004;KEGG: 00010+5.4.2.11;MetaCyc: PWY-5484 "Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)" XP_037814221.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037806364.1 5 Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-390471 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis" XP_037808029.1 6 Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6798695;Reactome: R-HSA-72163 "Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Neutrophil degranulation";"mRNA Splicing - Major Pathway" XP_037817302.1 4 KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;MetaCyc: PWY-7437 "Other types of O-glycan biosynthesis";"UCH proteinases";"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation" XP_037826240.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_037819064.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037815982.1 2 Reactome: R-HSA-432720;Reactome: R-HSA-432722 "Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis" XP_037822619.1 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" XP_037821756.1 17 Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-5358606;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-174417;Reactome: R-HSA-174437;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-174414;Reactome: R-HSA-5358565;Reactome: R-HSA-5651801 "Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Telomere C-strand (Lagging Strand) Synthesis";"Removal of the Flap Intermediate from the C-strand";"Polymerase switching";"Dual incision in TC-NER";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Processive synthesis on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"PCNA-Dependent Long Patch Base Excision Repair" XP_037821546.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037808250.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037809094.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" XP_037815458.1 6 KEGG: 00780+6.3.4.15;MetaCyc: PWY-7382;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;Reactome: R-HSA-3371599;Reactome: R-HSA-196780 "Biotin metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism" XP_037809505.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_037818698.1 11 Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-170670 "Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Hedgehog 'off' state";"Purine metabolism";"G alpha (z) signalling events";"G alpha (i) signalling events";"PKA activation";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway" XP_037816770.1 8 KEGG: 00521+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1 "Streptomycin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis";"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Fructose and mannose metabolism" XP_037807546.1 4 KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_037806610.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_037816066.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037808684.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037819880.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_037807217.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037815694.1 11 Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-418594 "G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"G alpha (z) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"PKA activation";"G alpha (i) signalling events" XP_037807467.1 6 MetaCyc: PWY-6124;KEGG: 00670+2.1.2.3;MetaCyc: PWY-7234;KEGG: 00230+3.5.4.10+2.1.2.3;Reactome: R-HSA-73817;MetaCyc: PWY-6123 "Inosine-5'-phosphate biosynthesis II";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I" XP_037817675.1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814 "Collagen chain trimerization";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes" XP_037810211.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_037814396.1 4 KEGG: 00330+4.1.1.50;MetaCyc: PWY-6834;KEGG: 00270+4.1.1.50;Reactome: R-HSA-351202 "Arginine and proline metabolism";"Spermidine biosynthesis III";"Cysteine and methionine metabolism";"Metabolism of polyamines" XP_037824680.1 18 Reactome: R-HSA-204174;Reactome: R-HSA-6783984;KEGG: 00010+1.8.1.4;KEGG: 00620+1.8.1.4;Reactome: R-HSA-70268;Reactome: R-HSA-71064;Reactome: R-HSA-389661;Reactome: R-HSA-5362517;MetaCyc: PWY-5046;KEGG: 00280+1.8.1.4;KEGG: 00020+1.8.1.4;KEGG: 00380+1.8.1.4;Reactome: R-HSA-70895;Reactome: R-HSA-71403;MetaCyc: PWY-5084;KEGG: 00260+1.8.1.4;KEGG: 00310+1.8.1.4;KEGG: 00640+1.8.1.4 "Regulation of pyruvate dehydrogenase (PDH) complex";"Glycine degradation";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Pyruvate metabolism";"Lysine catabolism";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Valine, leucine and isoleucine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Branched-chain amino acid catabolism";"Citric acid cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glycine, serine and threonine metabolism";"Lysine degradation";"Propanoate metabolism" XP_037811158.1 1 Reactome: R-HSA-6793080 "rRNA modification in the mitochondrion" XP_037806781.1 7 KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway" XP_037817264.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_037813672.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037815543.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_037813953.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037806332.1 14 MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7035;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7601 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_037822206.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_037808549.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_037807378.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037822515.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72764 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination" XP_037806476.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway" XP_037823769.1 3 Reactome: R-HSA-3214858;Reactome: R-HSA-6804760;Reactome: R-HSA-191859 "RMTs methylate histone arginines";"Regulation of TP53 Activity through Methylation";"snRNP Assembly" XP_037806854.1 15 MetaCyc: PWY-5723;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7218;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-6142;MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-6886;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7383;Reactome: R-HSA-70171;MetaCyc: PWY-2221;MetaCyc: PWY-8004 "Rubisco shunt";"Purine metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I" XP_037822566.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_037821270.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037816572.1 9 Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-191859;Reactome: R-HSA-381340;Reactome: R-HSA-2426168 "Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression";"PPARA activates gene expression";"snRNP Assembly";"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)" XP_037823560.1 42 Reactome: R-HSA-73728;Reactome: R-HSA-5250924;Reactome: R-HSA-69473;Reactome: R-HSA-5625886;Reactome: R-HSA-5693565;Reactome: R-HSA-1221632;Reactome: R-HSA-110331;Reactome: R-HSA-606279;Reactome: R-HSA-4551638;Reactome: R-HSA-8939236;Reactome: R-HSA-212300;Reactome: R-HSA-201722;Reactome: R-HSA-427413;Reactome: R-HSA-9018519;Reactome: R-HSA-73772;Reactome: R-HSA-110328;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-9609690;Reactome: R-HSA-3214858;Reactome: R-HSA-977225;Reactome: R-HSA-5578749;Reactome: R-HSA-3214841;Reactome: R-HSA-1912408;Reactome: R-HSA-110330;Reactome: R-HSA-5617472;Reactome: R-HSA-427359;Reactome: R-HSA-3214847;Reactome: R-HSA-9616222;Reactome: R-HSA-912446;Reactome: R-HSA-5334118;Reactome: R-HSA-171306;Reactome: R-HSA-9610379;Reactome: R-HSA-427389;Reactome: R-HSA-2559582;Reactome: R-HSA-3214815;Reactome: R-HSA-2299718;Reactome: R-HSA-3214842;Reactome: R-HSA-8936459;Reactome: R-HSA-2559586;Reactome: R-HSA-2559580;Reactome: R-HSA-110329 "RNA Polymerase I Promoter Opening";"B-WICH complex positively regulates rRNA expression";"G2/M DNA damage checkpoint";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Meiotic synapsis";"Cleavage of the damaged purine";"Deposition of new CENPA-containing nucleosomes at the centromere";"SUMOylation of chromatin organization proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"PRC2 methylates histones and DNA";"Formation of the beta-catenin:TCF transactivating complex";"NoRC negatively regulates rRNA expression";"Estrogen-dependent gene expression";"RNA Polymerase I Promoter Escape";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"HCMV Early Events";"RMTs methylate histone arginines";"Amyloid fiber formation";"Transcriptional regulation by small RNAs";"PKMTs methylate histone lysines";"Pre-NOTCH Transcription and Translation";"Recognition and association of DNA glycosylase with site containing an affected purine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SIRT1 negatively regulates rRNA expression";"HATs acetylate histones";"Transcriptional regulation of granulopoiesis";"Meiotic recombination";"DNA methylation";"Packaging Of Telomere Ends";"HCMV Late Events";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Senescence-Associated Secretory Phenotype (SASP)";"HDACs deacetylate histones";"Condensation of Prophase Chromosomes";"HDMs demethylate histones";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"DNA Damage/Telomere Stress Induced Senescence";"Oxidative Stress Induced Senescence";"Cleavage of the damaged pyrimidine" XP_037820978.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037818805.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation" XP_037812780.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037814522.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_037814102.1 26 Reactome: R-HSA-3899300;Reactome: R-HSA-201722;Reactome: R-HSA-400253;Reactome: R-HSA-210744;Reactome: R-HSA-9018519;Reactome: R-HSA-9013695;Reactome: R-HSA-8866907;Reactome: R-HSA-3214847;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472;Reactome: R-HSA-933541;Reactome: R-HSA-381340;Reactome: R-HSA-8941856;Reactome: R-HSA-9617629;Reactome: R-HSA-918233;Reactome: R-HSA-9614657;Reactome: R-HSA-9013508;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-3371568;Reactome: R-HSA-3134973;Reactome: R-HSA-1234158;Reactome: R-HSA-5621575;Reactome: R-HSA-1912408 "SUMOylation of transcription cofactors";"Formation of the beta-catenin:TCF transactivating complex";"Circadian Clock";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Estrogen-dependent gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"HATs acetylate histones";"RORA activates gene expression";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TRAF6 mediated IRF7 activation";"Transcriptional regulation of white adipocyte differentiation";"RUNX3 regulates NOTCH signaling";"Regulation of FOXO transcriptional activity by acetylation";"TRAF3-dependent IRF activation pathway";"FOXO-mediated transcription of cell death genes";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Attenuation phase";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression by Hypoxia-inducible Factor";"CD209 (DC-SIGN) signaling";"Pre-NOTCH Transcription and Translation" XP_037827827.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037812533.1 4 MetaCyc: PWY-5189;KEGG: 00860+4.2.1.75;Reactome: R-HSA-189451;MetaCyc: PWY-5188 "Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)" XP_037813083.1 1 Reactome: R-HSA-9018519 "Estrogen-dependent gene expression" XP_037818980.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_037821656.1 8 Reactome: R-HSA-6798695;Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-6803207;Reactome: R-HSA-111459;Reactome: R-HSA-8953750;Reactome: R-HSA-111464 "Neutrophil degranulation";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"Formation of apoptosome";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional Regulation by E2F6";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes" XP_037819491.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-983231 "Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production" XP_037806462.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037808324.1 4 Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_037811640.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_037815265.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037818557.1 57 Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-6798695;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-5689603;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-5676590 "Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Neutrophil degranulation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"UCH proteinases";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling" XP_037812084.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037818346.1 18 MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482925;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7409;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922 "Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PG";"Arachidonic acid metabolism";"Synthesis of PA";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI" XP_037817376.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037816033.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_037821273.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037828564.1 4 Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_037809534.1 24 Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-437239;Reactome: R-HSA-9648025;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-9609736;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-6811436;Reactome: R-HSA-983189 "Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Gap junction assembly";"HCMV Early Events";"Cilium Assembly";"Recycling pathway of L1";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Aggrephagy";"RHO GTPases Activate Formins";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins" XP_037808863.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037810898.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037817270.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037816054.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_037822612.1 11 Reactome: R-HSA-9018519;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-212436;Reactome: R-HSA-383280;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781 "Estrogen-dependent gene expression";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Generic Transcription Pathway";"Nuclear Receptor transcription pathway";"RORA activates gene expression";"PPARA activates gene expression" XP_037819776.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_037824597.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037808765.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037817387.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037818869.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037807928.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_037815730.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_037806427.1 22 Reactome: R-HSA-195253;Reactome: R-HSA-5467337;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-432142;Reactome: R-HSA-5358751;Reactome: R-HSA-5467348;Reactome: R-HSA-5358752;Reactome: R-HSA-9648025;Reactome: R-HSA-6811558;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-5673000;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-5675221;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262 "Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Platelet sensitization by LDL";"S45 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"RAF activation";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane" XP_037810390.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_037812042.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_037806612.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_037826309.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037805716.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037826971.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_037817182.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037810862.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037813128.1 6 MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism" XP_037812271.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037813187.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890 "T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling" XP_037828305.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037817708.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-429958 "KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease" XP_037805475.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037817853.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037812049.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_037824336.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037806548.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037812313.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_037827390.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_037823654.1 6 Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-399997 "G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion" XP_037817111.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_037812388.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037820742.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037822660.1 11 Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5358606;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5358565;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_037806282.1 3 Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546 "Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)" XP_037809031.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_037815101.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037818534.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037822819.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037822178.1 15 Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167152 "Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat" XP_037820073.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037817084.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_037806732.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_037814519.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_037817356.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037817930.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_037814729.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037819775.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_037815032.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_037817519.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_037813456.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I" XP_037816095.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_037820343.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037827972.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037826876.1 12 Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-6804756;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167238 "Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Regulation of TP53 Activity through Phosphorylation";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation" XP_037821443.1 19 Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-5673000;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-936837;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-111932;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-9617324 "Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"RAF activation";"RAF/MAP kinase cascade";"Long-term potentiation";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"CaMK IV-mediated phosphorylation of CREB";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_037815880.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037828216.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_037817790.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037805994.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_037827371.1 7 KEGG: 00521+3.1.3.25;MetaCyc: PWY-4702;MetaCyc: PWY-2301;KEGG: 00562+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.25 "Streptomycin biosynthesis";"Phytate degradation I";"Myo-inositol biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system" XP_037816854.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037828133.1 2 KEGG: 00260+2.3.1.29;Reactome: R-HSA-8849175 "Glycine, serine and threonine metabolism";"Threonine catabolism" XP_037828085.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_037826512.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037808614.1 3 Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_037824325.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037825352.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_037819493.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-983231 "Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production" XP_037806431.1 22 Reactome: R-HSA-4641262;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-389513;Reactome: R-HSA-5339716;Reactome: R-HSA-5675221;Reactome: R-HSA-5358747;Reactome: R-HSA-68877;Reactome: R-HSA-5358749;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-5673000;Reactome: R-HSA-5467348;Reactome: R-HSA-5358752;Reactome: R-HSA-9648025;Reactome: R-HSA-6811558;Reactome: R-HSA-432142;Reactome: R-HSA-5358751;Reactome: R-HSA-195253;Reactome: R-HSA-5467337;Reactome: R-HSA-2500257;Reactome: R-HSA-141444 "Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"CTLA4 inhibitory signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"Negative regulation of MAPK pathway";"S33 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"RAF activation";"Truncations of AMER1 destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Platelet sensitization by LDL";"S45 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_037807949.1 14 Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593 "Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity" XP_037807189.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037813741.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037806493.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037806629.1 8 Reactome: R-HSA-180024;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-442720 "DARPP-32 events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase" XP_037809670.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037824804.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037818841.1 7 Reactome: R-HSA-5578999;KEGG: 00270+6.3.2.2;Reactome: R-HSA-174403;MetaCyc: PWY-8043;MetaCyc: PWY-7255;MetaCyc: PWY-6840;KEGG: 00480+6.3.2.2 "Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Ergothioneine biosynthesis I (bacteria)";"Homoglutathione biosynthesis";"Glutathione metabolism" XP_037825473.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037823639.1 7 Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948 "NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_037815459.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037823195.1 6 Reactome: R-HSA-381426;Reactome: R-HSA-2173796;Reactome: R-HSA-8957275;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-5626467 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Post-translational protein phosphorylation";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"RHO GTPases activate IQGAPs" XP_037810972.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_037806762.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection" XP_037819979.1 6 Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-5685938 "Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)" XP_037805547.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037815691.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_037822501.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037813089.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037815332.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294 "SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors" XP_037825243.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_037807174.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037818926.1 3 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.4;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_037813226.1 10 Reactome: R-HSA-451308;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-447038;Reactome: R-HSA-9609736;Reactome: R-HSA-399719 "Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Synaptic adhesion-like molecules";"Long-term potentiation";"NrCAM interactions";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors" XP_037825088.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037814344.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_037823745.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_037805441.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway" XP_037813229.1 10 Reactome: R-HSA-451308;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932;Reactome: R-HSA-447038;Reactome: R-HSA-9609736;Reactome: R-HSA-399719 "Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Synaptic adhesion-like molecules";"NrCAM interactions";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors" XP_037828531.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_037807066.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_037815991.1 11 Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-5610787 "G alpha (z) signalling events";"Purine metabolism";"Glucagon signaling in metabolic regulation";"PKA activation";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state" XP_037817045.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037809089.1 6 KEGG: 00513+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-975578 "Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway" XP_037828222.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037806763.1 7 KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway" XP_037818369.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037817267.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037820786.1 1 Reactome: R-HSA-427359 "SIRT1 negatively regulates rRNA expression" XP_037824809.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_037820904.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037806432.1 22 Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-68877;Reactome: R-HSA-5675221;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-9648025;Reactome: R-HSA-6811558;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-5673000;Reactome: R-HSA-195253;Reactome: R-HSA-5467337;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-432142;Reactome: R-HSA-5358751 "Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Negative regulation of MAPK pathway";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"EML4 and NUDC in mitotic spindle formation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"RAF activation";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Platelet sensitization by LDL";"S45 mutants of beta-catenin aren't phosphorylated" XP_037809985.1 5 MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108 "Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_037805781.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037823519.1 4 Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434 "RHO GTPases activate KTN1";"Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037820777.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037813513.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_037818761.1 7 Reactome: R-HSA-445095;Reactome: R-HSA-373753;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-6798695;Reactome: R-HSA-264870;Reactome: R-HSA-375165 "Interaction between L1 and Ankyrins";"Nephrin family interactions";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins";"NCAM signaling for neurite out-growth" XP_037812838.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_037806955.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_037818124.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037812182.1 3 Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Tight junction interactions";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_037806613.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_037823166.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_037817791.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037821072.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_037807171.1 3 Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;Reactome: R-HSA-5696394 "UCH proteinases";"HATs acetylate histones";"DNA Damage Recognition in GG-NER" XP_037814532.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-8964539 "Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism" XP_037825589.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_037819915.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037811034.1 2 Reactome: R-HSA-8983711;Reactome: R-HSA-909733 "OAS antiviral response";"Interferon alpha/beta signaling" XP_037828104.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_037810614.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_037826602.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_037818692.1 11 KEGG: 00480+2.5.1.22;KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107;KEGG: 00330+2.5.1.16;MetaCyc: PWY-5194;MetaCyc: PWY-7377;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.22;MetaCyc: PWY-5196;KEGG: 00270+2.5.1.16 "Glutathione metabolism";"Porphyrin and chlorophyll metabolism";"Arginine and proline metabolism";"Siroheme biosynthesis";"Cob(ii)yrinate a,c-diamide biosynthesis I (early cobalt insertion)";"Metabolism of polyamines";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Factor 430 biosynthesis";"Cysteine and methionine metabolism" XP_037821334.1 10 KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-6798695;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2206292;Reactome: R-HSA-2024096 "Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Galactose metabolism";"Hyaluronan uptake and degradation";"Other glycan degradation";"MPS VII - Sly syndrome";"HS-GAG degradation" XP_037817908.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_037816688.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_037822598.1 7 Reactome: R-HSA-73817;MetaCyc: PWY-6123;MetaCyc: PWY-7234;KEGG: 00230+4.3.2.2;MetaCyc: PWY-7219;KEGG: 00250+4.3.2.2;MetaCyc: PWY-6124 "Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis II" XP_037823498.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_037810531.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037815135.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "COPII-mediated vesicle transport";"Cargo concentration in the ER" XP_037808466.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription" XP_037814814.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_037808855.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_037818361.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_037818884.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-6791226 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Peptide chain elongation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037808924.1 4 Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_037821354.1 3 KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II" XP_037814837.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_037807625.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_037827671.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037817436.1 12 Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-6804756;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-75955 "RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation" XP_037808836.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_037812076.1 17 MetaCyc: PWY-6545;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7197;MetaCyc: PWY-7187;MetaCyc: PWY-7176;MetaCyc: PWY-7224;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7220;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7198;MetaCyc: PWY-7205;MetaCyc: PWY-7226;MetaCyc: PWY-7210;MetaCyc: PWY-7221;MetaCyc: PWY-7227 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"CMP phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis" XP_037812766.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037822250.1 40 Reactome: R-HSA-72086;Reactome: R-HSA-72165;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-73776;Reactome: R-HSA-203927;Reactome: R-HSA-8851708;Reactome: R-HSA-167161;Reactome: R-HSA-113418;Reactome: R-HSA-6782135;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-72203;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-5601884;Reactome: R-HSA-75953;Reactome: R-HSA-6781823;Reactome: R-HSA-75955;Reactome: R-HSA-167160;Reactome: R-HSA-6781827;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-5617472;Reactome: R-HSA-6803529;Reactome: R-HSA-6782210;Reactome: R-HSA-167152;Reactome: R-HSA-72163;Reactome: R-HSA-167243;Reactome: R-HSA-5578749;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-168325;Reactome: R-HSA-73779;Reactome: R-HSA-6796648;Reactome: R-HSA-112382 "mRNA Capping";"mRNA Splicing - Minor Pathway";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Promoter Escape";"MicroRNA (miRNA) biogenesis";"Signaling by FGFR2 IIIa TM";"HIV Transcription Initiation";"Formation of the Early Elongation Complex";"Dual incision in TC-NER";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"FGFR2 alternative splicing";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Splicing - Major Pathway";"Tat-mediated HIV elongation arrest and recovery";"Transcriptional regulation by small RNAs";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex" XP_037810451.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037828081.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_037816103.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037828600.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037820236.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037807693.1 5 Reactome: R-HSA-196025;Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Formation of annular gap junctions";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037816339.1 8 KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6791226 "Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037815039.1 10 KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;MetaCyc: PWY-3841;Reactome: R-HSA-196757;MetaCyc: PWY-5497;MetaCyc: PWY-6613;MetaCyc: PWY-1722;MetaCyc: PWY-5030;MetaCyc: PWY-2201 "Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"L-histidine degradation III";"Folate transformations I" YP_001425551.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037816485.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_037806048.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_037814575.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037808401.1 5 Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_037815263.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037826837.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_037807186.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037812511.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_037822049.1 3 Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-110329 "Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine" XP_037815590.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037805381.1 10 Reactome: R-HSA-1855191;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6554;MetaCyc: PWY-6372;MetaCyc: PWY-6362;MetaCyc: PWY-6369;KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855167;MetaCyc: PWY-6361;MetaCyc: PWY-4661 "Synthesis of IPs in the nucleus";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)" XP_037817073.1 4 KEGG: 00790+1.14.16.4;KEGG: 00380+1.14.16.4;Reactome: R-HSA-209931;MetaCyc: PWY-6030 "Folate biosynthesis";"Tryptophan metabolism";"Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis" XP_037809744.1 7 KEGG: 00620+1.2.4.1;Reactome: R-HSA-204174;KEGG: 00010+1.2.4.1;Reactome: R-HSA-70268;KEGG: 00020+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-389661 "Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation" XP_037813800.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_037824816.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037814093.1 40 Reactome: R-HSA-6781823;Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-5601884;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-167161;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-203927;Reactome: R-HSA-8851708;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-72203;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-72165;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167172;Reactome: R-HSA-168325;Reactome: R-HSA-77075;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-6782210;Reactome: R-HSA-167246;Reactome: R-HSA-5578749;Reactome: R-HSA-167243;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-5617472;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-6803529 "Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PIWI-interacting RNA (piRNA) biogenesis";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"HIV Transcription Initiation";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"MicroRNA (miRNA) biogenesis";"Signaling by FGFR2 IIIa TM";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"mRNA Splicing - Minor Pathway";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Transcription of the HIV genome";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"Transcriptional regulation by small RNAs";"Tat-mediated HIV elongation arrest and recovery";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"FGFR2 alternative splicing" XP_037812837.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_037806769.1 7 Reactome: R-HSA-2122948;Reactome: R-HSA-1442490;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-177929 "Activated NOTCH1 Transmits Signal to the Nucleus";"Collagen degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Signaling by EGFR" XP_037816857.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037806859.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" XP_037822302.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037805546.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_037821724.1 6 Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176974 "Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Unwinding of DNA" XP_037812047.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_037821105.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037821668.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_037815177.1 24 Reactome: R-HSA-114604;KEGG: 04926+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2871837;Reactome: R-HSA-5218920;Reactome: R-HSA-354192;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5218921;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2730905;KEGG: 05165+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-5625740;Reactome: R-HSA-5607764;Reactome: R-HSA-1257604;KEGG: 05163+2.7.11.1;Reactome: R-HSA-202424;Reactome: R-HSA-444257;KEGG: 04714+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-9634635 "GPVI-mediated activation cascade";"Relaxin signaling pathway";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"mTOR signaling pathway";"FCERI mediated NF-kB activation";"VEGFR2 mediated vascular permeability";"Integrin signaling";"PI3K-Akt signaling pathway";"VEGFR2 mediated cell proliferation";"Human immunodeficiency virus 1 infection";"Role of LAT2/NTAL/LAB on calcium mobilization";"Human papillomavirus infection";"Activation of AKT2";"RHO GTPases activate PKNs";"CLEC7A (Dectin-1) signaling";"PIP3 activates AKT signaling";"Human cytomegalovirus infection";"Downstream TCR signaling";"RSK activation";"Thermogenesis";"G beta:gamma signalling through PI3Kgamma";"Estrogen-stimulated signaling through PRKCZ" XP_037808930.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037808560.1 7 MetaCyc: PWY-7511;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232 "Protein ubiquitination";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants" XP_037828635.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_037807070.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_037813236.1 10 Reactome: R-HSA-399719;Reactome: R-HSA-447038;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-451308;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932;Reactome: R-HSA-442982;Reactome: R-HSA-5673001 "Trafficking of AMPA receptors";"NrCAM interactions";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Activation of Ca-permeable Kainate Receptor";"Long-term potentiation";"Synaptic adhesion-like molecules";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade" XP_037814296.1 8 MetaCyc: PWY-6609;Reactome: R-HSA-5683826;KEGG: 00230+3.5.4.4;MetaCyc: PWY-6611;MetaCyc: PWY-7179;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;Reactome: R-HSA-6798695 "Adenine and adenosine salvage III";"Surfactant metabolism";"Purine metabolism";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation I";"Purine deoxyribonucleosides degradation II";"Purine salvage";"Neutrophil degranulation" XP_037810523.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037805661.1 5 MetaCyc: PWY-5381;MetaCyc: PWY-5653;Reactome: R-HSA-196807;KEGG: 00760+2.7.7.18;MetaCyc: PWY-7761 "Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)" XP_037807439.1 4 KEGG: 00564+3.1.1.7;Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085 "Glycerophospholipid metabolism";"Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin" XP_037817303.1 4 KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;MetaCyc: PWY-7437 "Other types of O-glycan biosynthesis";"UCH proteinases";"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation" XP_037807344.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037820137.1 56 Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-1169091;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-174184 "Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"UCH proteinases";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Activation of NF-kappaB in B cells";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A" XP_037819485.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_037824061.1 10 KEGG: 00562+5.3.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-7003;KEGG: 00010+5.3.1.1;Reactome: R-HSA-70263;KEGG: 00710+5.3.1.1;KEGG: 00051+5.3.1.1;Reactome: R-HSA-70171 "Inositol phosphate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Glycolysis" XP_037810543.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037812389.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037828611.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037805380.1 10 MetaCyc: PWY-6362;MetaCyc: PWY-6372;MetaCyc: PWY-6369;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-6554;MetaCyc: PWY-4661;MetaCyc: PWY-6361;KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855167 "1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol diphosphates biosynthesis";"Inositol phosphate metabolism";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol" XP_037824742.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_037818520.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037806430.1 22 Reactome: R-HSA-5673000;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-6811558;Reactome: R-HSA-9648025;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-5358751;Reactome: R-HSA-432142;Reactome: R-HSA-141444;Reactome: R-HSA-5467337;Reactome: R-HSA-2500257;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-5358749;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-5675221 "RAF activation";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"EML4 and NUDC in mitotic spindle formation";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"APC truncation mutants have impaired AXIN binding";"Resolution of Sister Chromatid Cohesion";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway" YP_001425549.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037816195.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7602;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619 "Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Juniperonate biosynthesis" XP_037818036.1 1 Reactome: R-HSA-8849175 "Threonine catabolism" XP_037826197.1 3 KEGG: 00350+1.13.11.5;KEGG: 00643+1.13.11.5;Reactome: R-HSA-8963684 "Tyrosine metabolism";"Styrene degradation";"Tyrosine catabolism" XP_037817330.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_037817973.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037807629.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_037806851.1 24 Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690 "The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Aggrephagy";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Gap junction assembly";"Cilium Assembly";"HCMV Early Events" XP_037825153.1 5 KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7268 "Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_037808554.1 13 KEGG: 00660+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-5913;MetaCyc: PWY-5538;MetaCyc: PWY-6969;KEGG: 00640+6.2.1.5;MetaCyc: PWY-7384;Reactome: R-HSA-71403;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5537 "C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V" XP_037806856.1 7 KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway" XP_037814737.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72649 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation" XP_037813511.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_037819475.1 7 KEGG: 00550+2.4.1.227;Reactome: R-HSA-5633231;MetaCyc: PWY-5265;MetaCyc: PWY-6385;Reactome: R-HSA-446193;MetaCyc: PWY-6471;MetaCyc: PWY-6470 "Peptidoglycan biosynthesis";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis III (mycobacteria)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis V (beta-lactam resistance)" XP_037817877.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689 "Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits" XP_037806850.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection" XP_037808418.1 32 Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-72086;Reactome: R-HSA-72165;Reactome: R-HSA-167238;Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-167161;Reactome: R-HSA-8851708;Reactome: R-HSA-72203;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-6803529;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167172;Reactome: R-HSA-168325;Reactome: R-HSA-77075;Reactome: R-HSA-73779 "Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"mRNA Capping";"mRNA Splicing - Minor Pathway";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"HIV Transcription Initiation";"Signaling by FGFR2 IIIa TM";"Processing of Capped Intron-Containing Pre-mRNA";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"FGFR2 alternative splicing";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Transcription of the HIV genome";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_037822673.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_037823256.1 3 Reactome: R-HSA-2995383;Reactome: R-HSA-4419969;Reactome: R-HSA-2980766 "Initiation of Nuclear Envelope Reformation";"Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown" XP_037821552.1 5 Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"COPII-mediated vesicle transport" XP_037810768.1 3 Reactome: R-HSA-140837;Reactome: R-HSA-111471;Reactome: R-HSA-9645722 "Intrinsic Pathway of Fibrin Clot Formation";"Apoptotic factor-mediated response";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function" XP_037827173.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_037820250.1 33 Reactome: R-HSA-6796648;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-6782210;Reactome: R-HSA-167246;Reactome: R-HSA-167160;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-6781823;Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-69656;Reactome: R-HSA-427413;Reactome: R-HSA-8939236;Reactome: R-HSA-75955;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-167161;Reactome: R-HSA-167158;Reactome: R-HSA-69202;Reactome: R-HSA-76042;Reactome: R-HSA-73772;Reactome: R-HSA-167162;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-72086;Reactome: R-HSA-69273;Reactome: R-HSA-5696395;Reactome: R-HSA-69231 "TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin A:Cdk2-associated events at S phase entry";"NoRC negatively regulates rRNA expression";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II Transcription Elongation";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"HIV Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Cyclin E associated events during G1/S transition";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"mRNA Capping";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of Incision Complex in GG-NER";"Cyclin D associated events in G1" XP_037823454.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037806862.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection" XP_037821440.1 19 Reactome: R-HSA-936837;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-9617324;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-9609736;Reactome: R-HSA-399719 "Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling downstream of RAS mutants";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"HSF1-dependent transactivation";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors" XP_037811759.1 13 Reactome: R-HSA-2022857;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52 "Keratan sulfate degradation";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series" XP_037809661.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037816817.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689 "Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Viral mRNA Translation";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" XP_037822602.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_037816501.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_037811032.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037818316.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_037810617.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037827635.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037811411.1 5 KEGG: 00240+2.4.2.3;MetaCyc: PWY-5532;Reactome: R-HSA-73621;Reactome: R-HSA-73614;KEGG: 00983+2.4.2.3 "Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine catabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes" XP_037814181.1 9 Reactome: R-HSA-4420097;Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-114604;Reactome: R-HSA-2871796;Reactome: R-HSA-416482;Reactome: R-HSA-2871809;Reactome: R-HSA-2029482;Reactome: R-HSA-5218920 "VEGFA-VEGFR2 Pathway";"Rho GTPase cycle";"NRAGE signals death through JNK";"GPVI-mediated activation cascade";"FCERI mediated MAPK activation";"G alpha (12/13) signalling events";"FCERI mediated Ca+2 mobilization";"Regulation of actin dynamics for phagocytic cup formation";"VEGFR2 mediated vascular permeability" XP_037819724.1 14 Reactome: R-HSA-1483213;MetaCyc: PWY-8051;KEGG: 00561+3.1.3.4;KEGG: 00600+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8052;Reactome: R-HSA-75109;MetaCyc: PWY-8053;KEGG: 00565+3.1.3.4;Reactome: R-HSA-1483191;Reactome: R-HSA-4419969;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-8055 "Synthesis of PE";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Sphingolipid metabolism";"Glycerophospholipid metabolism";"2-arachidonoylglycerol biosynthesis";"Triglyceride biosynthesis";"Anandamide biosynthesis II";"Ether lipid metabolism";"Synthesis of PC";"Depolymerisation of the Nuclear Lamina";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis" XP_037816510.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_037820850.1 8 Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-180024;Reactome: R-HSA-432040 "PKA activation in glucagon signalling";"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"DARPP-32 events";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_037812318.1 2 Reactome: R-HSA-977606;Reactome: R-HSA-166665 "Regulation of Complement cascade";"Terminal pathway of complement" XP_037814586.1 5 Reactome: R-HSA-110357;Reactome: R-HSA-5221030;Reactome: R-HSA-110328;Reactome: R-HSA-3108214;Reactome: R-HSA-110329 "Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Cleavage of the damaged pyrimidine" XP_037814217.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037807602.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037805533.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_037820075.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037828001.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646 "Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification" XP_037813235.1 10 Reactome: R-HSA-451308;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932;Reactome: R-HSA-447038;Reactome: R-HSA-9609736;Reactome: R-HSA-399719 "Activation of Ca-permeable Kainate Receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Synaptic adhesion-like molecules";"NrCAM interactions";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors" XP_037819329.1 2 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Synthesis of PG";"Synthesis of PA" XP_037817200.1 7 MetaCyc: PWY-7094;Reactome: R-HSA-1989781;Reactome: R-HSA-77288;Reactome: R-HSA-77348;Reactome: R-HSA-77346;KEGG: 00071+1.3.8.7;KEGG: 00280+1.3.8.7 "Fatty acid salvage";"PPARA activates gene expression";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Fatty acid degradation";"Valine, leucine and isoleucine degradation" XP_037811409.1 5 KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614;Reactome: R-HSA-73621;MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3 "Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism" XP_037817464.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037813453.1 8 KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Activation of RAC1";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_037807878.1 9 MetaCyc: PWY-6118;MetaCyc: PWY-7385;MetaCyc: PWY-7902;MetaCyc: PWY-5667;KEGG: 00564+1.1.1.94;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.8 "Glycerol-3-phosphate shuttle";"1,3-propanediol biosynthesis (engineered)";"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism" XP_037806075.1 9 MetaCyc: PWY-5664;MetaCyc: PWY-6703;KEGG: 00790+3.5.4.16;MetaCyc: PWY-5663;MetaCyc: PWY-7852;MetaCyc: PWY-7442;Reactome: R-HSA-1474151;MetaCyc: PWY-6147;MetaCyc: PWY-6983 "Erythro-tetrahydrobiopterin biosynthesis II";"Preq0 biosynthesis";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Drosopterin and aurodrosopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis" XP_037827127.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_037811252.1 10 KEGG: 00332+2.7.2.11;KEGG: 00330+1.2.1.41;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00330+2.7.2.11;MetaCyc: PWY-6922;KEGG: 00330+1.2.1.41+2.7.2.11;Reactome: R-HSA-8964539;KEGG: 00332+1.2.1.41 "Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"Carbapenem biosynthesis" XP_037815597.1 12 MetaCyc: PWY-7343;Reactome: R-HSA-173599;KEGG: 00520+2.7.7.9;Reactome: R-HSA-3322077;MetaCyc: PWY-7817;MetaCyc: PWY-7238;MetaCyc: PWY-6527;MetaCyc: PWY-3801;KEGG: 00052+2.7.7.9;KEGG: 00040+2.7.7.9;KEGG: 00500+2.7.7.9;KEGG: 00561+2.7.7.9 "UDP-alpha-D-glucose biosynthesis I";"Formation of the active cofactor, UDP-glucuronate";"Amino sugar and nucleotide sugar metabolism";"Glycogen synthesis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose biosynthesis II";"Stachyose degradation";"Sucrose degradation II (sucrose synthase)";"Galactose metabolism";"Pentose and glucuronate interconversions";"Starch and sucrose metabolism";"Glycerolipid metabolism" XP_037823964.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037815064.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_037821632.1 5 Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Cargo concentration in the ER" XP_037818017.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037827690.1 42 KEGG: 00360+4.2.1.17;MetaCyc: PWY-7007;KEGG: 00640+4.2.1.17;KEGG: 00903+4.2.1.17;MetaCyc: PWY-6945;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;MetaCyc: PWY-7778;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;MetaCyc: PWY-6435;KEGG: 00623+1.1.1.35;MetaCyc: PWY-6583;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;MetaCyc: PWY-5177;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7606;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7656;MetaCyc: PWY-5789;MetaCyc: PWY-7401;MetaCyc: PWY-7216;MetaCyc: PWY-6883;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6944;MetaCyc: PWY-7779;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;MetaCyc: PWY-1361;MetaCyc: PWY-5109;MetaCyc: PWY-7726 "Phenylalanine metabolism";"Methyl ketone biosynthesis (engineered)";"Propanoate metabolism";"Limonene and pinene degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Butanoate metabolism";"Tryptophan metabolism";"Fatty acid salvage";"2-methylpropene degradation";"Fatty acid degradation";"Fatty acid degradation";"Geraniol degradation";"Fatty acid elongation";"Fatty acid beta-oxidation II (plant peroxisome)";"4-hydroxybenzoate biosynthesis III (plants)";"Toluene degradation";"Pyruvate fermentation to butanol I";"Lysine degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Glutaryl-coa degradation";"Carbon fixation pathways in prokaryotes";"Benzoate degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Caprolactam degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"beta-Alanine metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Aminobenzoate degradation";"Spodoptera littoralis pheromone biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Pyruvate fermentation to butanol II (engineered)";"alpha-Linolenic acid metabolism";"Androstenedione degradation";"Methyl tert-butyl ether degradation";"Valine, leucine and isoleucine degradation";"Butanoate metabolism";"Pyruvate fermentation to hexanol (engineered)";"Benzoyl-coa degradation I (aerobic)";"Fermentation to 2-methylbutanoate";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)" XP_037828084.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_037819274.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_037810119.1 10 KEGG: 00052+5.1.3.2;MetaCyc: PWY-3821;MetaCyc: PWY-6397;MetaCyc: PWY-6527;Reactome: R-HSA-5609977;Reactome: R-HSA-70370;MetaCyc: PWY-7328;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-6317 "Galactose metabolism";"D-galactose detoxification";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Stachyose degradation";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose catabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis";"D-galactose degradation I (Leloir pathway)" XP_037820653.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection" XP_037819746.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_037813383.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037814208.1 6 MetaCyc: PWY-6737;MetaCyc: PWY-6731;Reactome: R-HSA-70221;KEGG: 00500+2.4.1.1;MetaCyc: PWY-5941;MetaCyc: PWY-7238 "Starch degradation V";"Starch degradation III";"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism";"Glycogen degradation II";"Sucrose biosynthesis II" XP_037817392.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_037820510.1 7 Reactome: R-HSA-3214815;Reactome: R-HSA-9029569;Reactome: R-HSA-983231;Reactome: R-HSA-8943724;Reactome: R-HSA-9018519;Reactome: R-HSA-5625886;Reactome: R-HSA-3214842 "HDACs deacetylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Factors involved in megakaryocyte development and platelet production";"Regulation of PTEN gene transcription";"Estrogen-dependent gene expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HDMs demethylate histones" XP_037809695.1 2 Reactome: R-HSA-6803205;Reactome: R-HSA-8873719 "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation" XP_037809506.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_037818232.1 3 Reactome: R-HSA-381426;Reactome: R-HSA-5362798;Reactome: R-HSA-8957275 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Release of Hh-Np from the secreting cell";"Post-translational protein phosphorylation" XP_037823819.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037809229.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_037820611.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037808821.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037814248.1 5 Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897 "Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes" XP_037814826.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037820636.1 4 KEGG: 00970+2.1.2.9;KEGG: 00670+1.5.1.6;KEGG: 00670+2.1.2.9;Reactome: R-HSA-196757 "Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"One carbon pool by folate";"Metabolism of folate and pterines" XP_037813100.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037805960.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_037807364.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037813251.1 5 Reactome: R-HSA-1912420;Reactome: R-HSA-1912408;Reactome: R-HSA-1912399;Reactome: R-HSA-350054;Reactome: R-HSA-5083630 "Pre-NOTCH Processing in Golgi";"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Notch-HLH transcription pathway";"Defective LFNG causes SCDO3" XP_037814223.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037828186.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037817649.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_037816458.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037805340.1 4 Reactome: R-HSA-3656532;Reactome: R-HSA-2173789;Reactome: R-HSA-3304356;Reactome: R-HSA-2173788 "TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"Downregulation of TGF-beta receptor signaling" XP_037808613.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers" XP_037809052.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" YP_001425541.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_037805279.1 6 Reactome: R-HSA-74259;MetaCyc: PWY-6606;MetaCyc: PWY-6608;KEGG: 00230+3.5.4.3;MetaCyc: PWY-5497;MetaCyc: PWY-7442 "Purine catabolism";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III";"Purine metabolism";"Purine nucleobases degradation II (anaerobic)";"Drosopterin and aurodrosopterin biosynthesis" XP_037814703.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_037813014.1 9 Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-75953 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation" XP_037827361.1 3 Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6 "Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism" XP_037817580.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037816072.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037810403.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037822543.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037810400.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037805376.1 10 MetaCyc: PWY-6361;MetaCyc: PWY-4661;KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855167;MetaCyc: PWY-6372;MetaCyc: PWY-6362;MetaCyc: PWY-6369;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-6554 "1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol diphosphates biosynthesis";"Inositol phosphate metabolism";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)" XP_037822203.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68827 "Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex" XP_037826778.1 3 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion" XP_037822644.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_037821503.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037810313.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-141444 "COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_037809093.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway" XP_037810974.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_037812748.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037817280.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037827138.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037822769.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037814535.1 14 MetaCyc: PWY-1622;MetaCyc: PWY-5497;MetaCyc: PWY-2161;MetaCyc: PWY-2201;KEGG: 00260+2.1.2.1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-181;MetaCyc: PWY-3661;MetaCyc: PWY-3841;KEGG: 00630+2.1.2.1;KEGG: 00460+2.1.2.1;KEGG: 00680+2.1.2.1;Reactome: R-HSA-196757;MetaCyc: PWY-3661-1 "Formaldehyde assimilation I (serine pathway)";"Purine nucleobases degradation II (anaerobic)";"Folate polyglutamylation";"Folate transformations I";"Glycine, serine and threonine metabolism";"One carbon pool by folate";"Photorespiration ";"Glycine betaine degradation I";"Folate transformations II (plants)";"Glyoxylate and dicarboxylate metabolism";"Cyanoamino acid metabolism";"Methane metabolism";"Metabolism of folate and pterines";"Glycine betaine degradation II (mammalian)" XP_037827669.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037827287.1 6 KEGG: 00230+4.1.1.21;MetaCyc: PWY-6124;KEGG: 00230+6.3.2.6;MetaCyc: PWY-7234;Reactome: R-HSA-73817;MetaCyc: PWY-6123 "Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I" XP_037825304.1 5 Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-430039 "ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease" XP_037807929.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_037812039.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_037826370.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037822266.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037819067.1 5 KEGG: 00562+3.1.3.36;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1660499;Reactome: R-HSA-8856828;MetaCyc: PWY-6368 "Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"Clathrin-mediated endocytosis";"3-phosphoinositide degradation" XP_037820592.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037813110.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037819941.1 12 Reactome: R-HSA-380972;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5628897;KEGG: 04714+2.7.11.1 "Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Macroautophagy";"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"TP53 Regulates Metabolic Genes";"Thermogenesis" XP_037828057.1 6 Reactome: R-HSA-1989781;Reactome: R-HSA-9029569;Reactome: R-HSA-3214815;Reactome: R-HSA-9022537;Reactome: R-HSA-9609690;Reactome: R-HSA-9022692 "PPARA activates gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDACs deacetylate histones";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"HCMV Early Events";"Regulation of MECP2 expression and activity" XP_037823790.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037810683.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037816686.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_037809691.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706 "Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037807064.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_037811805.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_037823711.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_037824483.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-68884;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434 "Kinesins";"Mitotic Telophase/Cytokinesis";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037810643.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037822921.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037807875.1 9 Reactome: R-HSA-1483166;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7411;MetaCyc: PWY-7385;MetaCyc: PWY-6118;MetaCyc: PWY-5667;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7902 "Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"1,3-propanediol biosynthesis (engineered)";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis" XP_037812626.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037825439.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_037815330.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300 "SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors" XP_037811426.1 5 Reactome: R-HSA-73614;KEGG: 00983+2.4.2.3;MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73621 "Pyrimidine salvage";"Drug metabolism - other enzymes";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism";"Pyrimidine catabolism" XP_037813613.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_037821361.1 3 MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33 "Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_037815441.1 3 Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2 "Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism" XP_037821490.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_037807298.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_037823895.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_037828602.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037818992.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037807751.1 14 Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-203927;Reactome: R-HSA-4086398 "Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway" XP_037822376.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_037818900.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs" XP_037815591.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037822813.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037805409.1 11 Reactome: R-HSA-1257604;Reactome: R-HSA-1963642;Reactome: R-HSA-1227986;Reactome: R-HSA-5673001;Reactome: R-HSA-1250196;Reactome: R-HSA-2219530;Reactome: R-HSA-9664565;Reactome: R-HSA-8863795;Reactome: R-HSA-8847993;Reactome: R-HSA-6785631;Reactome: R-HSA-6811558 "PIP3 activates AKT signaling";"PI3K events in ERBB2 signaling";"Signaling by ERBB2";"RAF/MAP kinase cascade";"SHC1 events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by ERBB2 KD Mutants";"Downregulation of ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"ERBB2 Regulates Cell Motility";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_037822922.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037816075.1 3 KEGG: 00564+4.1.1.65;Reactome: R-HSA-1483213;MetaCyc: PWY-5669 "Glycerophospholipid metabolism";"Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I" XP_037824990.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_037823994.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_037825360.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037823965.1 3 MetaCyc: PWY-7546;MetaCyc: PWY-6482;Reactome: R-HSA-5358493 "Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2" XP_037819116.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037828724.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037817391.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_037809585.1 3 Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-5689877 "Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"Josephin domain DUBs" XP_037814546.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037821353.1 3 MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33 "Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_037816127.1 11 Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-5610787 "G alpha (z) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"PKA activation";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state" XP_037822731.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037811205.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037806780.1 7 Reactome: R-HSA-2691232;Reactome: R-HSA-177929;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-1442490;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_037812993.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037822348.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_037822818.1 8 Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-8866652;Reactome: R-HSA-6782135;Reactome: R-HSA-8948747;Reactome: R-HSA-5689880;Reactome: R-HSA-6781827;Reactome: R-HSA-6804757 "Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Dual incision in TC-NER";"Regulation of PTEN localization";"Ub-specific processing proteases";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of TP53 Degradation" XP_037808286.1 4 Reactome: R-HSA-176187;Reactome: R-HSA-69205;Reactome: R-HSA-176974;Reactome: R-HSA-68962 "Activation of ATR in response to replication stress";"G1/S-Specific Transcription";"Unwinding of DNA";"Activation of the pre-replicative complex" XP_037819757.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_037811297.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037814244.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_037805571.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_037805479.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037810642.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037816511.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_037815719.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_037814100.1 26 Reactome: R-HSA-8866907;Reactome: R-HSA-9013695;Reactome: R-HSA-9018519;Reactome: R-HSA-210744;Reactome: R-HSA-201722;Reactome: R-HSA-3899300;Reactome: R-HSA-400253;Reactome: R-HSA-1234158;Reactome: R-HSA-5621575;Reactome: R-HSA-1912408;Reactome: R-HSA-3371568;Reactome: R-HSA-3134973;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-918233;Reactome: R-HSA-9614657;Reactome: R-HSA-9013508;Reactome: R-HSA-381340;Reactome: R-HSA-8941856;Reactome: R-HSA-9617629;Reactome: R-HSA-933541;Reactome: R-HSA-3214847;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472 "Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH4 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Formation of the beta-catenin:TCF transactivating complex";"SUMOylation of transcription cofactors";"Circadian Clock";"Regulation of gene expression by Hypoxia-inducible Factor";"CD209 (DC-SIGN) signaling";"Pre-NOTCH Transcription and Translation";"Attenuation phase";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"TRAF3-dependent IRF activation pathway";"FOXO-mediated transcription of cell death genes";"NOTCH3 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation";"RUNX3 regulates NOTCH signaling";"Regulation of FOXO transcriptional activity by acetylation";"TRAF6 mediated IRF7 activation";"HATs acetylate histones";"PPARA activates gene expression";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_037809818.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_037809011.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037813438.1 23 Reactome: R-HSA-418594;Reactome: R-HSA-418592;Reactome: R-HSA-392170;Reactome: R-HSA-8964616;Reactome: R-HSA-416482;Reactome: R-HSA-428930;Reactome: R-HSA-418597;Reactome: R-HSA-392451;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-416476;Reactome: R-HSA-4086398;Reactome: R-HSA-381676;Reactome: R-HSA-418217;Reactome: R-HSA-420092;Reactome: R-HSA-500657;Reactome: R-HSA-400042;Reactome: R-HSA-8964315;Reactome: R-HSA-9009391;Reactome: R-HSA-6814122;Reactome: R-HSA-392851;Reactome: R-HSA-202040;Reactome: R-HSA-456926 "G alpha (i) signalling events";"ADP signalling through P2Y purinoceptor 1";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through CDC42";"G alpha (12/13) signalling events";"Thromboxane signalling through TP receptor";"G alpha (z) signalling events";"G beta:gamma signalling through PI3Kgamma";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (q) signalling events";"Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PLC beta";"Glucagon-type ligand receptors";"Presynaptic function of Kainate receptors";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through BTK";"Extra-nuclear estrogen signaling";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prostacyclin signalling through prostacyclin receptor";"G-protein activation";"Thrombin signalling through proteinase activated receptors (PARs)" XP_037807960.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination" XP_037807547.1 4 KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"DARPP-32 events";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037828122.1 7 Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-1362300 "G1/S-Specific Transcription";"G0 and Early G1";"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1" XP_037817168.1 2 Reactome: R-HSA-5576886;Reactome: R-HSA-1299308 "Phase 4 - resting membrane potential";"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)" XP_037805863.1 13 KEGG: 04926+2.7.11.1;Reactome: R-HSA-5627117;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-3928662;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-3928663;Reactome: R-HSA-416482;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1 "Relaxin signaling pathway";"RHO GTPases Activate ROCKs";"mTOR signaling pathway";"Human cytomegalovirus infection";"VEGFA-VEGFR2 Pathway";"EPHB-mediated forward signaling";"Thermogenesis";"Sema4D induced cell migration and growth-cone collapse";"EPHA-mediated growth cone collapse";"G alpha (12/13) signalling events";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection" XP_037818908.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037826479.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_037809940.1 11 Reactome: R-HSA-3656237;Reactome: R-HSA-202733;Reactome: R-HSA-3560801;Reactome: R-HSA-2024096;Reactome: R-HSA-3000170;Reactome: R-HSA-2022928;Reactome: R-HSA-1971475;Reactome: R-HSA-4420332;Reactome: R-HSA-3560783;Reactome: R-HSA-3656253;Reactome: R-HSA-975634 "Defective EXT2 causes exostoses 2";"Cell surface interactions at the vascular wall";"Defective B3GAT3 causes JDSSDHD";"HS-GAG degradation";"Syndecan interactions";"HS-GAG biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Retinoid metabolism and transport" XP_037820885.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037817474.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037819349.1 5 KEGG: 00330+1.5.1.2;MetaCyc: PWY-3341;MetaCyc: PWY-6344;Reactome: R-HSA-8964539;MetaCyc: PWY-4981 "Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)" XP_037806342.1 14 MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7724;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7602 "Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_037813854.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_037805239.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037813802.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_037810557.1 4 MetaCyc: PWY-4841;Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1;KEGG: 00562+1.13.99.1 "UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism";"Inositol phosphate metabolism" XP_037825343.1 3 MetaCyc: PWY-6367;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6368 "D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation" XP_037809520.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_037816603.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_037806403.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037822333.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_037822968.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-71403 "Mitochondrial protein import";"Citric acid cycle (TCA cycle)" XP_037825006.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706 "Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037807175.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_037819833.1 56 Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-1169091;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880 "Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"UCH proteinases";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Activation of NF-kappaB in B cells";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"Degradation of AXIN";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases" XP_037828633.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_037820566.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037828163.1 28 Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-68962;Reactome: R-HSA-5358565;Reactome: R-HSA-6804756;Reactome: R-HSA-69166;Reactome: R-HSA-176187;Reactome: R-HSA-6782135;Reactome: R-HSA-5693616;Reactome: R-HSA-3371511;Reactome: R-HSA-5693607;Reactome: R-HSA-110312;Reactome: R-HSA-5685938;Reactome: R-HSA-174437;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-912446;Reactome: R-HSA-110320;Reactome: R-HSA-5358606;Reactome: R-HSA-110314;Reactome: R-HSA-6783310;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-3371453 "Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Activation of the pre-replicative complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate";"Activation of ATR in response to replication stress";"Dual incision in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"HSF1 activation";"Processing of DNA double-strand break ends";"Translesion synthesis by REV1";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate from the C-strand";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Meiotic recombination";"Translesion Synthesis by POLH";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Recognition of DNA damage by PCNA-containing replication complex";"Fanconi Anemia Pathway";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Regulation of HSF1-mediated heat shock response" XP_037816732.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037827940.1 6 Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-8951430 "Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling" XP_037806238.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037806809.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_037822976.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037818700.1 11 MetaCyc: PWY-7377;Reactome: R-HSA-351202;MetaCyc: PWY-5194;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00480+2.5.1.22;KEGG: 00330+2.5.1.16;KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107;MetaCyc: PWY-5196;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.22 "Cob(ii)yrinate a,c-diamide biosynthesis I (early cobalt insertion)";"Metabolism of polyamines";"Siroheme biosynthesis";"Glutathione metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Porphyrin and chlorophyll metabolism";"Factor 430 biosynthesis";"Cysteine and methionine metabolism";"Arginine and proline metabolism" XP_037806843.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_037823556.1 42 Reactome: R-HSA-5693565;Reactome: R-HSA-5625886;Reactome: R-HSA-5250924;Reactome: R-HSA-69473;Reactome: R-HSA-73728;Reactome: R-HSA-606279;Reactome: R-HSA-110331;Reactome: R-HSA-1221632;Reactome: R-HSA-9018519;Reactome: R-HSA-427413;Reactome: R-HSA-4551638;Reactome: R-HSA-8939236;Reactome: R-HSA-212300;Reactome: R-HSA-201722;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-9609690;Reactome: R-HSA-110328;Reactome: R-HSA-73772;Reactome: R-HSA-1912408;Reactome: R-HSA-3214841;Reactome: R-HSA-110330;Reactome: R-HSA-5578749;Reactome: R-HSA-977225;Reactome: R-HSA-3214858;Reactome: R-HSA-912446;Reactome: R-HSA-5617472;Reactome: R-HSA-9616222;Reactome: R-HSA-427359;Reactome: R-HSA-3214847;Reactome: R-HSA-9610379;Reactome: R-HSA-171306;Reactome: R-HSA-5334118;Reactome: R-HSA-2559586;Reactome: R-HSA-8936459;Reactome: R-HSA-2559580;Reactome: R-HSA-110329;Reactome: R-HSA-2299718;Reactome: R-HSA-3214842;Reactome: R-HSA-427389;Reactome: R-HSA-2559582;Reactome: R-HSA-3214815 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"B-WICH complex positively regulates rRNA expression";"G2/M DNA damage checkpoint";"RNA Polymerase I Promoter Opening";"Deposition of new CENPA-containing nucleosomes at the centromere";"Cleavage of the damaged purine";"Meiotic synapsis";"Estrogen-dependent gene expression";"NoRC negatively regulates rRNA expression";"SUMOylation of chromatin organization proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"PRC2 methylates histones and DNA";"Formation of the beta-catenin:TCF transactivating complex";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"HCMV Early Events";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"RNA Polymerase I Promoter Escape";"Pre-NOTCH Transcription and Translation";"PKMTs methylate histone lysines";"Recognition and association of DNA glycosylase with site containing an affected purine";"Transcriptional regulation by small RNAs";"Amyloid fiber formation";"RMTs methylate histone arginines";"Meiotic recombination";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of granulopoiesis";"SIRT1 negatively regulates rRNA expression";"HATs acetylate histones";"HCMV Late Events";"Packaging Of Telomere Ends";"DNA methylation";"DNA Damage/Telomere Stress Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Oxidative Stress Induced Senescence";"Cleavage of the damaged pyrimidine";"Condensation of Prophase Chromosomes";"HDMs demethylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Senescence-Associated Secretory Phenotype (SASP)";"HDACs deacetylate histones" XP_037828695.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037812386.1 2 Reactome: R-HSA-166665;Reactome: R-HSA-977606 "Terminal pathway of complement";"Regulation of Complement cascade" XP_037817811.1 6 Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-390471 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis" XP_037806271.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_037810246.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037817671.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_037817544.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_037806089.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_037812471.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037806992.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_037826756.1 3 KEGG: 00511+3.2.1.45;KEGG: 00600+3.2.1.45;Reactome: R-HSA-1660662 "Other glycan degradation";"Sphingolipid metabolism";"Glycosphingolipid metabolism" XP_037806139.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_037827876.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_037826968.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_037813287.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_037806783.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection" XP_037828027.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037811305.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037814213.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037815152.1 5 Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.24;Reactome: R-HSA-168638;Reactome: R-HSA-171007;Reactome: R-HSA-376172 "VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"NOD1/2 Signaling Pathway";"p38MAPK events";"DSCAM interactions" XP_037817364.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037827881.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037815698.1 3 KEGG: 00260+3.1.3.3;KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347 "Glycine, serine and threonine metabolism";"Methane metabolism";"Serine biosynthesis" XP_037828319.1 16 Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-9633012 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Viral mRNA Translation";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_037822378.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037822653.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037823558.1 42 Reactome: R-HSA-5693565;Reactome: R-HSA-5625886;Reactome: R-HSA-5250924;Reactome: R-HSA-69473;Reactome: R-HSA-73728;Reactome: R-HSA-606279;Reactome: R-HSA-110331;Reactome: R-HSA-1221632;Reactome: R-HSA-9018519;Reactome: R-HSA-427413;Reactome: R-HSA-4551638;Reactome: R-HSA-8939236;Reactome: R-HSA-212300;Reactome: R-HSA-201722;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-9609690;Reactome: R-HSA-110328;Reactome: R-HSA-73772;Reactome: R-HSA-1912408;Reactome: R-HSA-3214841;Reactome: R-HSA-110330;Reactome: R-HSA-977225;Reactome: R-HSA-5578749;Reactome: R-HSA-3214858;Reactome: R-HSA-912446;Reactome: R-HSA-5617472;Reactome: R-HSA-427359;Reactome: R-HSA-3214847;Reactome: R-HSA-9616222;Reactome: R-HSA-9610379;Reactome: R-HSA-171306;Reactome: R-HSA-5334118;Reactome: R-HSA-8936459;Reactome: R-HSA-2559586;Reactome: R-HSA-2559580;Reactome: R-HSA-110329;Reactome: R-HSA-3214842;Reactome: R-HSA-2299718;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-2559582 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"B-WICH complex positively regulates rRNA expression";"G2/M DNA damage checkpoint";"RNA Polymerase I Promoter Opening";"Deposition of new CENPA-containing nucleosomes at the centromere";"Cleavage of the damaged purine";"Meiotic synapsis";"Estrogen-dependent gene expression";"NoRC negatively regulates rRNA expression";"SUMOylation of chromatin organization proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"PRC2 methylates histones and DNA";"Formation of the beta-catenin:TCF transactivating complex";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"HCMV Early Events";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"RNA Polymerase I Promoter Escape";"Pre-NOTCH Transcription and Translation";"PKMTs methylate histone lysines";"Recognition and association of DNA glycosylase with site containing an affected purine";"Amyloid fiber formation";"Transcriptional regulation by small RNAs";"RMTs methylate histone arginines";"Meiotic recombination";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SIRT1 negatively regulates rRNA expression";"HATs acetylate histones";"Transcriptional regulation of granulopoiesis";"HCMV Late Events";"Packaging Of Telomere Ends";"DNA methylation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"DNA Damage/Telomere Stress Induced Senescence";"Oxidative Stress Induced Senescence";"Cleavage of the damaged pyrimidine";"HDMs demethylate histones";"Condensation of Prophase Chromosomes";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Senescence-Associated Secretory Phenotype (SASP)" XP_037827046.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" XP_037811604.1 2 Reactome: R-HSA-446193;Reactome: R-HSA-4570571 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)" XP_037807324.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_037810545.1 8 Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-68962 "Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex" XP_037825871.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_037821626.1 1 Reactome: R-HSA-419771 "Opsins" XP_037814607.1 3 Reactome: R-HSA-8964208;KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1 "Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism" XP_037809198.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-6790901 "Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol" XP_037826515.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037811913.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037826516.1 2 Reactome: R-HSA-8875656;Reactome: R-HSA-8873719 "MET receptor recycling";"RAB geranylgeranylation" XP_037814822.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037824839.1 7 Reactome: R-HSA-70263;KEGG: 00051+3.1.3.11;KEGG: 00680+3.1.3.11;KEGG: 00010+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00710+3.1.3.11;KEGG: 00030+3.1.3.11 "Gluconeogenesis";"Fructose and mannose metabolism";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway" XP_037810239.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037821185.1 5 KEGG: 00230+6.3.5.3;MetaCyc: PWY-6121;MetaCyc: PWY-6277;Reactome: R-HSA-73817;MetaCyc: PWY-6122 "Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II" XP_037820412.1 3 Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21 "Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system" XP_037810568.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" XP_037823572.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_037806999.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_037827629.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037824180.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_037805531.1 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" XP_037817523.1 10 Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-611105;Reactome: R-HSA-111459;Reactome: R-HSA-111457;Reactome: R-HSA-111458;Reactome: R-HSA-111463;Reactome: R-HSA-2151201;Reactome: R-HSA-5628897;Reactome: R-HSA-3299685 "SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"Respiratory electron transport";"Activation of caspases through apoptosome-mediated cleavage";"Release of apoptotic factors from the mitochondria";"Formation of apoptosome";"SMAC (DIABLO) binds to IAPs";"Transcriptional activation of mitochondrial biogenesis";"TP53 Regulates Metabolic Genes";"Detoxification of Reactive Oxygen Species" XP_037811757.1 13 MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52 "Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series" XP_037824417.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037806765.1 7 KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis" XP_037828580.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037812091.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037818657.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_037819088.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037814531.1 5 Reactome: R-HSA-164843;Reactome: R-HSA-6798695;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;Reactome: R-HSA-3270619 "2-LTR circle formation";"Neutrophil degranulation";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN" XP_037809713.1 4 Reactome: R-HSA-964975;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7204;MetaCyc: PWY-7282 "Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis" XP_037807799.1 9 Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554 "Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_037814180.1 9 Reactome: R-HSA-5218920;Reactome: R-HSA-2029482;Reactome: R-HSA-416482;Reactome: R-HSA-2871809;Reactome: R-HSA-2871796;Reactome: R-HSA-114604;Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-4420097 "VEGFR2 mediated vascular permeability";"Regulation of actin dynamics for phagocytic cup formation";"G alpha (12/13) signalling events";"FCERI mediated Ca+2 mobilization";"FCERI mediated MAPK activation";"GPVI-mediated activation cascade";"Rho GTPase cycle";"NRAGE signals death through JNK";"VEGFA-VEGFR2 Pathway" XP_037810440.1 3 KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I" XP_037823157.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection" XP_037826929.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_037822707.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037805254.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037815092.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037818099.1 4 MetaCyc: PWY-5041;MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;Reactome: R-HSA-156581 "S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"Methylation" XP_037823712.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037814211.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037828442.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037817803.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_037809300.1 29 KEGG: 00830+1.1.1.1;MetaCyc: PWY-7013;MetaCyc: PWY-6313;MetaCyc: PWY-5079;MetaCyc: PWY-3162;MetaCyc: PWY-5480;MetaCyc: PWY-5082;MetaCyc: PWY-5751;MetaCyc: PWY-6802;KEGG: 00350+1.1.1.1;MetaCyc: PWY-7396;MetaCyc: PWY-5486;MetaCyc: PWY-5076;KEGG: 00626+1.1.1.1;KEGG: 00625+1.1.1.1;KEGG: 00071+1.1.1.1;KEGG: 00980+1.1.1.1;MetaCyc: PWY-6333;KEGG: 00260+1.1.1.1;MetaCyc: PWY-7111;KEGG: 00982+1.1.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-6587;MetaCyc: PWY-5057;MetaCyc: PWY-6871;KEGG: 00592+1.1.1.1;MetaCyc: PWY-5078;KEGG: 00010+1.1.1.1;MetaCyc: PWY-6342 "Retinol metabolism";"(S)-propane-1,2-diol degradation";"Serotonin degradation";"L-phenylalanine degradation III";"L-tryptophan degradation V (side chain pathway)";"Pyruvate fermentation to ethanol I";"L-methionine degradation III";"Phenylethanol biosynthesis";"Salidroside biosynthesis";"Tyrosine metabolism";"Butanol and isobutanol biosynthesis (engineered)";"Pyruvate fermentation to ethanol II";"L-leucine degradation III";"Naphthalene degradation";"Chloroalkane and chloroalkene degradation";"Fatty acid degradation";"Metabolism of xenobiotics by cytochrome P450";"Acetaldehyde biosynthesis I";"Glycine, serine and threonine metabolism";"Pyruvate fermentation to isobutanol (engineered)";"Drug metabolism - cytochrome P450";"Chitin degradation to ethanol";"Pyruvate fermentation to ethanol III";"L-valine degradation II";"3-methylbutanol biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"L-isoleucine degradation II";"Glycolysis / Gluconeogenesis";"Noradrenaline and adrenaline degradation" XP_037808688.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037805793.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_037825415.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_037819816.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_037827431.1 4 Reactome: R-HSA-112043;Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "PLC beta mediated events";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_037807275.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037824221.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_037825969.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037805375.1 10 MetaCyc: PWY-6369;MetaCyc: PWY-6362;MetaCyc: PWY-6372;MetaCyc: PWY-6554;Reactome: R-HSA-1855191;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6361;MetaCyc: PWY-4661;Reactome: R-HSA-1855167;KEGG: 04070+2.7.1.158 "Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of IPs in the nucleus";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system" XP_037824492.1 3 KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism" XP_037813983.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037825893.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling" XP_037815100.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037828169.1 7 Reactome: R-HSA-9018681;Reactome: R-HSA-9018896;Reactome: R-HSA-9018676;Reactome: R-HSA-9023661;Reactome: R-HSA-6798695;Reactome: R-HSA-2142691;Reactome: R-HSA-9020265 "Biosynthesis of protectins";"Biosynthesis of E-series 18(S)-resolvins";"Biosynthesis of D-series resolvins";"Biosynthesis of E-series 18(R)-resolvins";"Neutrophil degranulation";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Biosynthesis of aspirin-triggered D-series resolvins" XP_037807284.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037823477.1 4 Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-110312;Reactome: R-HSA-5656121 "Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1";"Translesion synthesis by POLI" XP_037816222.1 5 Reactome: R-HSA-9648895;Reactome: R-HSA-8963693;Reactome: R-HSA-9633012;Reactome: R-HSA-380994;KEGG: 00250+6.3.5.4 "Response of EIF2AK1 (HRI) to heme deficiency";"Aspartate and asparagine metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Alanine, aspartate and glutamate metabolism" XP_037812797.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_037819044.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037807473.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037828298.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037815867.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1660662 "Neutrophil degranulation";"Glycosphingolipid metabolism" XP_037808754.1 8 Reactome: R-HSA-2426168;MetaCyc: PWY-6174;MetaCyc: PWY-922;MetaCyc: PWY-7524;MetaCyc: PWY-7391;Reactome: R-HSA-1989781;Reactome: R-HSA-191273;KEGG: 00900+1.1.1.34 "Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway II (archaea)";"Mevalonate pathway I";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"PPARA activates gene expression";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis" XP_037819574.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037828144.1 2 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Synthesis of PG";"Synthesis of PA" XP_037825340.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_037807062.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_037820626.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037818799.1 29 Reactome: R-HSA-5685942;KEGG: 04151+2.7.11.1;Reactome: R-HSA-69473;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693568;Reactome: R-HSA-5693565;Reactome: R-HSA-6804757;Reactome: R-HSA-6803207;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-5693548;KEGG: 04926+2.7.11.1;Reactome: R-HSA-912446;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-6796648;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804760;Reactome: R-HSA-69541;Reactome: R-HSA-6803204;Reactome: R-HSA-5693554;Reactome: R-HSA-349425;Reactome: R-HSA-5685938;Reactome: R-HSA-5693571;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586 "HDR through Homologous Recombination (HRR)";"PI3K-Akt signaling pathway";"G2/M DNA damage checkpoint";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Degradation";"TP53 Regulates Transcription of Caspase Activators and Caspases";"mTOR signaling pathway";"Regulation of HSF1-mediated heat shock response";"Sensing of DNA Double Strand Breaks";"Relaxin signaling pathway";"Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"TP53 Regulates Transcription of DNA Repair Genes";"Thermogenesis";"Human cytomegalovirus infection";"Regulation of TP53 Activity through Methylation";"Stabilization of p53";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Autodegradation of the E3 ubiquitin ligase COP1";"HDR through Single Strand Annealing (SSA)";"Nonhomologous End-Joining (NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence" XP_037808750.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_037821525.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320 "Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes" XP_037822953.1 6 Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-212676 "Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" XP_037824119.1 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" XP_037820162.1 57 Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-4641258;Reactome: R-HSA-6798695;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-69017 "Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Orc1 removal from chromatin";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"UCH proteinases";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"Degradation of DVL";"Neutrophil degranulation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6" XP_037826424.1 3 KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;MetaCyc: PWY-7382 "Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)" XP_037817336.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_037806627.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037815943.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_037805864.1 13 Reactome: R-HSA-5627117;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-3928662;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3928663;Reactome: R-HSA-416572;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-416482 "RHO GTPases Activate ROCKs";"Relaxin signaling pathway";"Human cytomegalovirus infection";"VEGFA-VEGFR2 Pathway";"EPHB-mediated forward signaling";"mTOR signaling pathway";"EPHA-mediated growth cone collapse";"Sema4D induced cell migration and growth-cone collapse";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"G alpha (12/13) signalling events" XP_037814413.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_037808844.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_037825257.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_037811301.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037808604.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers" XP_037826952.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037821142.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_037817271.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037816057.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037822907.1 2 Reactome: R-HSA-8869496;Reactome: R-HSA-1268020 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import" XP_037810325.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-68877 "COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase" XP_037827838.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_037805238.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764 "Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination" XP_037826150.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037822971.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_037807906.1 18 KEGG: 00250+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00220+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00270+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00400+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-6638;MetaCyc: PWY-7383;MetaCyc: PWY-7115 "Alanine, aspartate and glutamate metabolism";"Carbon fixation in photosynthetic organisms";"Novobiocin biosynthesis";"Arginine and proline metabolism";"Phenylalanine metabolism";"(R)-cysteate degradation";"Arginine biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Cysteine and methionine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"Coenzyme M biosynthesis II";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Sulfolactate degradation III";"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" XP_037810709.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-110320 "Ub-specific processing proteases";"Translesion Synthesis by POLH" XP_037816039.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037815180.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434 "Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037806229.1 2 MetaCyc: PWY-7800;MetaCyc: PWY-7799 "Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)" XP_037817735.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037818721.1 9 MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7385;MetaCyc: PWY-6118;MetaCyc: PWY-5667;MetaCyc: PWY-7902;KEGG: 00564+1.1.1.94 "CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis I";"Glucosylglycerol biosynthesis";"Glycerophospholipid metabolism" XP_037828066.1 6 Reactome: R-HSA-9022692;Reactome: R-HSA-9609690;Reactome: R-HSA-9022537;Reactome: R-HSA-3214815;Reactome: R-HSA-9029569;Reactome: R-HSA-1989781 "Regulation of MECP2 expression and activity";"HCMV Early Events";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"HDACs deacetylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"PPARA activates gene expression" XP_037806841.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_037816620.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" XP_037810022.1 2 Reactome: R-HSA-419812;Reactome: R-HSA-418555 "Calcitonin-like ligand receptors";"G alpha (s) signalling events" XP_037805404.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037828103.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_037826587.1 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" XP_037812854.1 3 Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191 "Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC" XP_037807621.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_037814265.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037814412.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_037821674.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037818469.1 3 Reactome: R-HSA-6785470;Reactome: R-HSA-6787450;Reactome: R-HSA-8868766 "tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion" XP_037815793.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037821841.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037819980.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_037814902.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037820450.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_037818995.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037822860.1 8 Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962 "Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex" XP_037827154.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_037826396.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_037820759.1 3 Reactome: R-HSA-381038;Reactome: R-HSA-381426;Reactome: R-HSA-8957275 "XBP1(S) activates chaperone genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation" XP_037820665.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_037811244.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037819450.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037811910.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037812413.1 6 Reactome: R-HSA-3000171;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-8874081;Reactome: R-HSA-2022090 "Non-integrin membrane-ECM interactions";"Collagen degradation";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures" XP_037806325.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7602;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-5972 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)" XP_037805846.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037813230.1 10 Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932;Reactome: R-HSA-442982;Reactome: R-HSA-451308;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-447038;Reactome: R-HSA-399719 "RAF/MAP kinase cascade";"Long-term potentiation";"Synaptic adhesion-like molecules";"Ras activation upon Ca2+ influx through NMDA receptor";"Activation of Ca-permeable Kainate Receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"NrCAM interactions";"Trafficking of AMPA receptors" XP_037809712.1 4 MetaCyc: PWY-7204;MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5;Reactome: R-HSA-964975 "Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate" XP_037815702.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" XP_037825238.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_037812396.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037826724.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_037827249.1 6 Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-69052 "Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state" XP_037805997.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_037822060.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037821523.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259 "Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes" XP_037822750.1 9 Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-1971475;Reactome: R-HSA-2024096;Reactome: R-HSA-2022928;Reactome: R-HSA-3560783;Reactome: R-HSA-4420332;Reactome: R-HSA-3656253;Reactome: R-HSA-975634 "Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG degradation";"HS-GAG biosynthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Retinoid metabolism and transport" XP_037818269.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_037806328.1 14 MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7724;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7602 "Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_037809331.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037820594.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_037812731.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_037818731.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037810160.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_037815977.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_037807942.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5689880 "UCH proteinases";"Ub-specific processing proteases" XP_037823607.1 5 KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2 "Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)" XP_037820070.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037805659.1 5 MetaCyc: PWY-7761;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5381;MetaCyc: PWY-5653;Reactome: R-HSA-196807 "NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism" XP_037822583.1 5 Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-72163 "Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway" XP_037823550.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037815105.1 10 MetaCyc: PWY-7112;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-4061;MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842 "4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Glutathione metabolism";"Glutathione-mediated detoxification II" XP_037815003.1 4 MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism" XP_037824550.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037812467.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037820764.1 3 Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_037817559.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_037808472.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_037812370.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037823355.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-1660662;Reactome: R-HSA-4341670;Reactome: R-HSA-4085001 "MHC class II antigen presentation";"Neutrophil degranulation";"Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis";"Sialic acid metabolism" XP_037806422.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_037821833.1 6 Reactome: R-HSA-72165;Reactome: R-HSA-111367;Reactome: R-HSA-73856;Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-77588 "mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"snRNP Assembly";"mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" XP_037810924.1 5 KEGG: 00250+1.2.1.88;MetaCyc: PWY-6853;KEGG: 00330+1.2.1.88;Reactome: R-HSA-70688;Reactome: R-HSA-389661 "Alanine, aspartate and glutamate metabolism";"Ethylene biosynthesis II (microbes)";"Arginine and proline metabolism";"Proline catabolism";"Glyoxylate metabolism and glycine degradation" XP_037821876.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-1799339 "Peptide chain elongation";"Viral mRNA Translation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane" XP_037816170.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-195253 "Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex" XP_037807206.1 3 Reactome: R-HSA-8963684;KEGG: 00350+3.7.1.2;KEGG: 00643+3.7.1.2 "Tyrosine catabolism";"Tyrosine metabolism";"Styrene degradation" XP_037806882.1 15 MetaCyc: PWY-8004;MetaCyc: PWY-7383;MetaCyc: PWY-2221;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-5484;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-1042;MetaCyc: PWY-6142;MetaCyc: PWY-5723;MetaCyc: PWY-6901;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7218;KEGG: 00230+2.7.1.40 "Entner-Doudoroff pathway I";"Anaerobic energy metabolism (invertebrates, cytosol)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis";"Glycerol degradation to butanol";"Glycolysis II (from fructose 6-phosphate)";"Pyruvate metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Rubisco shunt";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Purine metabolism" XP_037810905.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_037814237.1 10 MetaCyc: PWY-8053;MetaCyc: PWY-7411;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15;KEGG: 00564+2.3.1.15 "Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Glycerophospholipid metabolism" XP_037816174.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_037814219.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037805477.1 56 Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-5689603;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-174178 "NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"UCH proteinases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_037813951.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037814491.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037810550.1 7 Reactome: R-HSA-1855183;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.25;MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25;MetaCyc: PWY-2301;KEGG: 00562+3.1.3.25 "Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Phytate degradation I";"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"Inositol phosphate metabolism" XP_037823799.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-167161 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"HIV Transcription Initiation" XP_037816018.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037810050.1 3 Reactome: R-HSA-114608;Reactome: R-HSA-194313;Reactome: R-HSA-195399 "Platelet degranulation";"VEGF ligand-receptor interactions";"VEGF binds to VEGFR leading to receptor dimerization" XP_037823788.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_037813098.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037824497.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037822463.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_037805959.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_037806993.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_037819269.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_037811856.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037817191.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037819642.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_037813978.1 22 Reactome: R-HSA-70263;Reactome: R-HSA-5628897;MetaCyc: PWY-3801;MetaCyc: PWY-5514;MetaCyc: PWY-8013;MetaCyc: PWY-5659;MetaCyc: PWY-6142;KEGG: 00010+5.3.1.9;MetaCyc: PWY-7238;KEGG: 00520+5.3.1.9;MetaCyc: PWY-621;Reactome: R-HSA-70171;MetaCyc: PWY-6981;Reactome: R-HSA-6798695;MetaCyc: PWY-5054;KEGG: 00500+5.3.1.9;MetaCyc: PWY-6992;MetaCyc: PWY-5384;MetaCyc: PWY-7385;MetaCyc: PWY-622;KEGG: 00030+5.3.1.9;MetaCyc: PWY-7347 "Gluconeogenesis";"TP53 Regulates Metabolic Genes";"Sucrose degradation II (sucrose synthase)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"UDP-N-acetyl-D-galactosamine biosynthesis III";"GDP-mannose biosynthesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Sucrose biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Sucrose degradation III (sucrose invertase)";"Glycolysis";"Chitin biosynthesis";"Neutrophil degranulation";"D-sorbitol biosynthesis I";"Starch and sucrose metabolism";"1,5-anhydrofructose degradation";"Sucrose degradation IV (sucrose phosphorylase)";"1,3-propanediol biosynthesis (engineered)";"Starch biosynthesis";"Pentose phosphate pathway";"Sucrose biosynthesis III" XP_037821809.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037821227.1 4 MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32;KEGG: 00592+3.1.1.32 "Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism" XP_037828230.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037821495.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037813972.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037808552.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037814910.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_037825476.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037806981.1 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097 "T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway" XP_037825590.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_037822424.1 13 Reactome: R-HSA-937072;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-450321;Reactome: R-HSA-5357956;Reactome: R-HSA-168638;Reactome: R-HSA-9645460;Reactome: R-HSA-975163;Reactome: R-HSA-937042;Reactome: R-HSA-445989;Reactome: R-HSA-5607764;Reactome: R-HSA-9014325;Reactome: R-HSA-450302 "TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TNFR1-induced NFkappaB signaling pathway";"NOD1/2 Signaling Pathway";"Alpha-protein kinase 1 signaling pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"IRAK2 mediated activation of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"CLEC7A (Dectin-1) signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"activated TAK1 mediates p38 MAPK activation" XP_037809259.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037828803.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037813178.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_037819460.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_037810539.1 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" XP_037815290.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037827833.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_037812093.1 8 Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68827 "E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex" XP_037819988.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_037813065.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037817733.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_037808502.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection" XP_037807040.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_037816644.1 2 Reactome: R-HSA-5663220;Reactome: R-HSA-376176 "RHO GTPases Activate Formins";"Signaling by ROBO receptors" XP_037817235.1 56 Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-5610783;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-174084 "AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"UCH proteinases";"Orc1 removal from chromatin";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"Degradation of GLI2 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C" XP_037825679.1 8 Reactome: R-HSA-8854518;Reactome: R-HSA-6804115;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942 "AURKA Activation by TPX2";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition" XP_037825526.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037821050.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-1268020 "Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import" XP_037806550.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037828773.1 6 Reactome: R-HSA-5654693;Reactome: R-HSA-5654706;Reactome: R-HSA-9028731;Reactome: R-HSA-5654700;Reactome: R-HSA-5654712;Reactome: R-HSA-5673001 "FRS-mediated FGFR1 signaling";"FRS-mediated FGFR3 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR4 signaling";"RAF/MAP kinase cascade" XP_037815603.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_037825665.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037826263.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_037828821.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037824189.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037807088.1 4 Reactome: R-HSA-210991;Reactome: R-HSA-5660862;Reactome: R-HSA-71240;Reactome: R-HSA-352230 "Basigin interactions";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism";"Amino acid transport across the plasma membrane" XP_037821231.1 4 KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32 "Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism" XP_037813628.1 5 KEGG: 00480+6.3.2.3;KEGG: 00270+6.3.2.3;Reactome: R-HSA-174403;MetaCyc: PWY-8043;Reactome: R-HSA-5579006 "Glutathione metabolism";"Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)" XP_037823062.1 3 Reactome: R-HSA-8856828;Reactome: R-HSA-8854214;Reactome: R-HSA-8875656 "Clathrin-mediated endocytosis";"TBC/RABGAPs";"MET receptor recycling" XP_037826039.1 4 MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112;MetaCyc: PWY-7174 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" XP_037827535.1 5 Reactome: R-HSA-5083630;Reactome: R-HSA-350054;Reactome: R-HSA-1912399;Reactome: R-HSA-1912420;Reactome: R-HSA-1912408 "Defective LFNG causes SCDO3";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Transcription and Translation" XP_037814812.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037814451.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_037808773.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_037808906.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_037828808.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037809997.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037810130.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037814613.1 4 Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052 "Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion" XP_037819150.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037805440.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_037818655.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_037823861.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_037807951.1 14 Reactome: R-HSA-426496;Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-8943723;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519 "Post-transcriptional silencing by small RNAs";"MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression" XP_037828164.1 28 Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-69473;Reactome: R-HSA-5656121;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-912446;Reactome: R-HSA-5358606;Reactome: R-HSA-6783310;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-3371453;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-68962;Reactome: R-HSA-5358565;Reactome: R-HSA-6804756;Reactome: R-HSA-69166;Reactome: R-HSA-6782135;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-3371511;Reactome: R-HSA-110312;Reactome: R-HSA-5685938;Reactome: R-HSA-174437 "Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"G2/M DNA damage checkpoint";"Translesion synthesis by POLI";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Fanconi Anemia Pathway";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Regulation of HSF1-mediated heat shock response";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Activation of the pre-replicative complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate";"Dual incision in TC-NER";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"HSF1 activation";"Translesion synthesis by REV1";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate from the C-strand" XP_037809260.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_037823565.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037809150.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_037811091.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037824186.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_037810358.1 14 Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-1632852;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-5620924 "MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Macroautophagy";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"Aggrephagy";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Intraflagellar transport" XP_037814577.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_037815041.1 10 MetaCyc: PWY-5030;MetaCyc: PWY-2201;MetaCyc: PWY-1722;MetaCyc: PWY-5497;MetaCyc: PWY-6613;Reactome: R-HSA-196757;MetaCyc: PWY-3841;MetaCyc: PWY-7909;KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00720+1.5.1.5+3.5.4.9 "L-histidine degradation III";"Folate transformations I";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Metabolism of folate and pterines";"Folate transformations II (plants)";"Formaldehyde oxidation VII (THF pathway)";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes" XP_037817344.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_037824549.1 5 MetaCyc: PWY-6344;Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2 "L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism" XP_037812457.1 3 Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1 "Aspartate and asparagine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism" XP_037823180.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_037813801.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_037809564.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037814712.1 4 KEGG: 00532+2.4.2.26;KEGG: 00534+2.4.2.26;Reactome: R-HSA-1971475;MetaCyc: PWY-6557 "Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan-protein linkage region biosynthesis" XP_037822103.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037820485.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_037807393.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_037812045.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_037811709.1 2 Reactome: R-HSA-8876725;Reactome: R-HSA-611105 "Protein methylation";"Respiratory electron transport" XP_037812107.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_037812495.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037805566.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-2408557 "SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis" XP_037806870.1 15 MetaCyc: PWY-6886;MetaCyc: PWY-5484;KEGG: 00620+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-8004;MetaCyc: PWY-2221;MetaCyc: PWY-7383;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6901;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-5723;MetaCyc: PWY-6142 "1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Pyruvate metabolism";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Purine metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_037819387.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_037828445.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_037810264.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037814297.1 6 MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;MetaCyc: PWY-5067;Reactome: R-HSA-189085;KEGG: 00500+3.2.1.1 "Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_037822205.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.9 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_037808999.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_037810636.1 5 Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825 "InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis" XP_037821838.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037815339.1 2 Reactome: R-HSA-191859;Reactome: R-HSA-6807505 "snRNP Assembly";"RNA polymerase II transcribes snRNA genes" XP_037817705.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037825369.1 14 MetaCyc: PWY-7417;Reactome: R-HSA-975634;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8051;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4 "Phospholipid remodeling (phosphatidate, yeast)";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Ether lipid metabolism" XP_037823539.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037817548.1 20 KEGG: 00410+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7854;MetaCyc: PWY-7574;Reactome: R-HSA-9033241;MetaCyc: PWY-7338;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7291;KEGG: 00071+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7288;MetaCyc: PWY-6837;MetaCyc: PWY-5136;MetaCyc: PWY-7337;MetaCyc: PWY-735;MetaCyc: PWY-7340;MetaCyc: PWY-7726;MetaCyc: PWY-7858 "beta-Alanine metabolism";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoyl-coa degradation II";"Peroxisomal protein import";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation II (plant peroxisome)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Jasmonic acid biosynthesis";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(5Z)-dodecenoate biosynthesis II" XP_037825895.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037807403.1 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_037809000.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_037813469.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_037819173.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037806392.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037808085.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_037823664.1 5 Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-389357 "VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling" XP_037814404.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_037819071.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037808989.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037827329.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_037816490.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_037809987.1 5 KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-197264;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108 "Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_037814233.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_037826832.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling" XP_037819415.1 3 Reactome: R-HSA-6783984;KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine degradation";"Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_037811760.1 13 KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2024101 "Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"CS/DS degradation" XP_037813730.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037821108.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_037807877.1 9 MetaCyc: PWY-7385;MetaCyc: PWY-6118;MetaCyc: PWY-5667;MetaCyc: PWY-7902;KEGG: 00564+1.1.1.94;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.8 "1,3-propanediol biosynthesis (engineered)";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis I";"Glucosylglycerol biosynthesis";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism" XP_037827649.1 5 Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855 "Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)" XP_037816171.1 2 Reactome: R-HSA-195253;Reactome: R-HSA-5689896 "Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases" XP_037820603.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_037815312.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037809621.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037814424.1 5 KEGG: 00900+2.7.4.2;Reactome: R-HSA-191273;MetaCyc: PWY-7391;MetaCyc: PWY-922;Reactome: R-HSA-2426168 "Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)" XP_037814696.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037806565.1 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" XP_037817357.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037812773.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037813458.1 6 MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" XP_037819677.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-194840 "RAB GEFs exchange GTP for GDP on RABs";"Rho GTPase cycle" XP_037828377.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_037811908.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037812038.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_037826339.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_037817879.1 4 Reactome: R-HSA-936440;Reactome: R-HSA-1632852;Reactome: R-HSA-5205685;Reactome: R-HSA-8934903 "Negative regulators of DDX58/IFIH1 signaling";"Macroautophagy";"Pink/Parkin Mediated Mitophagy";"Receptor Mediated Mitophagy" XP_037812036.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_037821923.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-75035 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex" XP_037816027.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037813162.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037815962.1 26 Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-389960;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-1445148;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-190840;Reactome: R-HSA-437239;Reactome: R-HSA-389977;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-190861 "Aggrephagy";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"Formation of tubulin folding intermediates by CCT/TriC";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recycling pathway of L1";"Post-chaperonin tubulin folding pathway";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"HCMV Early Events";"Gap junction assembly" XP_037812181.1 3 MetaCyc: PWY-7221;Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions";"Purine metabolism" XP_037824415.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037812737.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_037817187.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_037820509.1 1 Reactome: R-HSA-1483101 "Synthesis of PS" XP_037815310.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037810634.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037810598.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_037824190.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037819722.1 14 KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053;Reactome: R-HSA-4419969;Reactome: R-HSA-1483191;MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-6453;Reactome: R-HSA-1483213;MetaCyc: PWY-8051;KEGG: 00564+3.1.3.4;KEGG: 00561+3.1.3.4;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052;Reactome: R-HSA-75109 "Ether lipid metabolism";"Anandamide biosynthesis II";"Depolymerisation of the Nuclear Lamina";"Synthesis of PC";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Synthesis of PE";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Triglyceride biosynthesis" XP_037822781.1 7 KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483148;Reactome: R-HSA-1483166;Reactome: R-HSA-2029485;MetaCyc: PWY-3561;KEGG: 00565+3.1.4.4;MetaCyc: PWY-7039 "Glycerophospholipid metabolism";"Synthesis of PG";"Synthesis of PA";"Role of phospholipids in phagocytosis";"Choline biosynthesis III";"Ether lipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_037818730.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037818283.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037814346.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_037817750.1 3 MetaCyc: PWY-4361;Reactome: R-HSA-1237112;KEGG: 00270+1.13.11.54 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"Cysteine and methionine metabolism" XP_037817809.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037815166.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_037813225.1 10 Reactome: R-HSA-9609736;Reactome: R-HSA-447038;Reactome: R-HSA-399719;Reactome: R-HSA-451308;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-442982 "Assembly and cell surface presentation of NMDA receptors";"NrCAM interactions";"Trafficking of AMPA receptors";"Activation of Ca-permeable Kainate Receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Synaptic adhesion-like molecules";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor" XP_037810147.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724 "RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription" XP_037819822.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_037816805.1 1 Reactome: R-HSA-1483166 "Synthesis of PA" XP_037807394.1 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_037826742.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_037827113.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_037808068.1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_037807545.1 4 KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"DARPP-32 events";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037817349.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037806124.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_037822377.1 56 Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-5362768;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-5610783;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-174084 "Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"UCH proteinases";"Orc1 removal from chromatin";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"Degradation of GLI2 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C" XP_037818516.1 7 Reactome: R-HSA-2151201;Reactome: R-HSA-1268020;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210;Reactome: R-HSA-8949613;MetaCyc: PWY-7980 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial protein import";"Oxidative phosphorylation";"Photosynthesis";"Formation of ATP by chemiosmotic coupling";"Cristae formation";"ATP biosynthesis" XP_037819766.1 7 Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-177929 "Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Signaling by EGFR" XP_037812946.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226 "Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037807967.1 4 KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202 "Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines" XP_037814927.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_037818413.1 14 KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7783;MetaCyc: PWY-8051;MetaCyc: PWY-7416;MetaCyc: PWY-7409;Reactome: R-HSA-975634;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4 "Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Linoleic acid metabolism" XP_037810887.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975957 "Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Viral mRNA Translation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_037812193.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_037805443.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_037808767.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_037821312.1 3 Reactome: R-HSA-8936459;Reactome: R-HSA-400206;Reactome: R-HSA-427413 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of lipid metabolism by PPARalpha";"NoRC negatively regulates rRNA expression" XP_037822537.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037816059.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_037809972.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037827664.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" YP_001425539.1 7 KEGG: 00190+7.1.1.2;Reactome: R-HSA-611105;MetaCyc: PWY-4302;MetaCyc: PWY-5083;MetaCyc: PWY-3781;MetaCyc: PWY-6692;Reactome: R-HSA-6799198 "Oxidative phosphorylation";"Respiratory electron transport";"Aerobic respiration III (alternative oxidase pathway)";"NAD/NADH phosphorylation and dephosphorylation";"Aerobic respiration I (cytochrome c)";"Fe(II) oxidation";"Complex I biogenesis" XP_037805649.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037827451.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72764 "Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination" XP_037814619.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037814788.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226 "Selenocysteine synthesis";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037821920.1 5 Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897 "Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes" XP_037820401.1 1 Reactome: R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" XP_037808601.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers" XP_037827892.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_037810109.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_037820625.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037828271.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_037824208.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_037810635.1 1 Reactome: R-HSA-419771 "Opsins" XP_037825779.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037824604.1 1 Reactome: R-HSA-2465910 "MASTL Facilitates Mitotic Progression" XP_037810389.1 3 Reactome: R-HSA-6794361;Reactome: R-HSA-9609736;Reactome: R-HSA-212676 "Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors";"Dopamine Neurotransmitter Release Cycle" XP_037815427.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037815234.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_037818100.1 4 MetaCyc: PWY-5041;Reactome: R-HSA-156581;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912 "S-adenosyl-L-methionine cycle II";"Methylation";"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis" XP_037809615.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037823937.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_037816247.1 5 KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I" XP_037821536.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037818854.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_037814387.1 9 KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway" XP_037809583.1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" XP_037822281.1 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" XP_037809630.1 22 Reactome: R-HSA-432142;Reactome: R-HSA-5358751;Reactome: R-HSA-5467337;Reactome: R-HSA-2500257;Reactome: R-HSA-195253;Reactome: R-HSA-141444;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-5673000;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-6811558;Reactome: R-HSA-9648025;Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-5675221;Reactome: R-HSA-5358749;Reactome: R-HSA-4641262;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220 "Platelet sensitization by LDL";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Resolution of Sister Chromatid Cohesion";"Degradation of beta-catenin by the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"RAF activation";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"EML4 and NUDC in mitotic spindle formation";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"S37 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Separation of Sister Chromatids";"RHO GTPases Activate Formins" XP_037828861.1 8 Reactome: R-HSA-4608870;Reactome: R-HSA-4086398;Reactome: R-HSA-5340588;Reactome: R-HSA-4641263;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900;Reactome: R-HSA-373080;Reactome: R-HSA-8856825 "Asymmetric localization of PCP proteins";"Ca2+ pathway";"RNF mutants show enhanced WNT signaling and proliferation";"Regulation of FZD by ubiquitination";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Class B/2 (Secretin family receptors)";"Cargo recognition for clathrin-mediated endocytosis" XP_037813105.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037807785.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_037810441.1 7 Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877 "RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase" XP_037828598.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037823170.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_037819437.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037822740.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037826510.1 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" XP_037818713.1 7 MetaCyc: PWY-7210;MetaCyc: PWY-7185;MetaCyc: PWY-7198;MetaCyc: PWY-7184;KEGG: 00730+3.6.1.15;KEGG: 00230+3.6.1.15;MetaCyc: PWY-6545 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Thiamine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" XP_037827147.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_037821446.1 19 Reactome: R-HSA-9617324;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-9609736;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"Assembly and cell surface presentation of NMDA receptors";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Long-term potentiation";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation" XP_037824617.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037824198.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_037819959.1 7 KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis" XP_037824232.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_037812462.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037822124.1 17 Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5685939;Reactome: R-HSA-5693554;Reactome: R-HSA-5693571;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-1834949;Reactome: R-HSA-5693565;Reactome: R-HSA-5693568;Reactome: R-HSA-3270619;Reactome: R-HSA-5693548;Reactome: R-HSA-912446 "Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"HDR through MMEJ (alt-NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Cytosolic sensors of pathogen-associated DNA";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"IRF3-mediated induction of type I IFN";"Sensing of DNA Double Strand Breaks";"Meiotic recombination" XP_037817300.1 4 KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;MetaCyc: PWY-7437 "Other types of O-glycan biosynthesis";"UCH proteinases";"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation" XP_037808609.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers" XP_037818645.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037813382.1 56 Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5689603;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-4641258;Reactome: R-HSA-8939236;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-2871837 "G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"UCH proteinases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"Degradation of DVL";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation" XP_037824812.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_037808564.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_037817248.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_037812377.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037825789.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_037810967.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" XP_037821265.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-162658 "COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization" XP_037811912.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037811784.1 10 MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-5826 "Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis" XP_037824624.1 16 Reactome: R-HSA-69017;Reactome: R-HSA-176409;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-174184 "CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A" XP_037827871.1 3 MetaCyc: PWY-6689;MetaCyc: PWY-7803;Reactome: R-HSA-6784531 "Trna splicing I";"Trna splicing II";"tRNA processing in the nucleus" XP_037823282.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_037810115.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_037823507.1 8 Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-165054;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids" XP_037827291.1 4 KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051 "alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Anandamide biosynthesis I" XP_037810315.1 12 Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436 "Mitotic Prometaphase";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic" XP_037806982.1 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097 "T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway" XP_037825283.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037827215.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037826059.1 9 KEGG: 00401+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00130+2.6.1.5;Reactome: R-HSA-8963684 "Novobiocin biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Cysteine and methionine metabolism";"Tyrosine metabolism";"Phenylalanine metabolism";"Isoquinoline alkaloid biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Tyrosine catabolism" XP_037823902.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-5576893 "NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase" XP_037811946.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_037819517.1 11 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-171007;KEGG: 04714+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-450302;Reactome: R-HSA-2559580 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"p38MAPK events";"Thermogenesis";"VEGFA-VEGFR2 Pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"activated TAK1 mediates p38 MAPK activation";"Oxidative Stress Induced Senescence" XP_037822053.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037810832.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_037819089.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037819038.1 14 Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-8055;MetaCyc: PWY-7587;MetaCyc: PWY-7417;MetaCyc: PWY-5981;MetaCyc: PWY-7782;MetaCyc: PWY-7589;MetaCyc: PWY-8053;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.51;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-8051 "Synthesis of PA";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I" XP_037810034.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037810909.1 2 Reactome: R-HSA-3108214;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination" XP_037827201.1 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" XP_037806761.1 7 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway" XP_037807023.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037824830.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037808940.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037808829.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037809602.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_037825074.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_037824769.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_037820540.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_037805625.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037820776.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037810527.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037812161.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_037814745.1 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" XP_037826403.1 18 Reactome: R-HSA-1482801;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7409;Reactome: R-HSA-1483166;MetaCyc: PWY-7783;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416 "Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Acyl chain remodelling of PG";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Synthesis of PA";"Plasmalogen degradation";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)" XP_037825141.1 2 Reactome: R-HSA-8950505;Reactome: R-HSA-1237112 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway" XP_037816616.1 10 MetaCyc: PWY-5839;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5892;MetaCyc: PWY-5891;MetaCyc: PWY-5895;MetaCyc: PWY-5849;MetaCyc: PWY-5890;MetaCyc: PWY-7996;MetaCyc: PWY-5844;Reactome: R-HSA-2142789 "Menaquinol-7 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-9 biosynthesis";"Ubiquinol biosynthesis" XP_037807413.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7619;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199 "(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation" XP_037822020.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_037823754.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_037806322.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037805494.1 4 Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922;MetaCyc: PWY-5737 "Proline catabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis" XP_037823892.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation" XP_037813102.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037811587.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_037827167.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_037805666.1 5 Reactome: R-HSA-879415;Reactome: R-HSA-901042;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-532668 "Advanced glycosylation endproduct receptor signaling";"Calnexin/calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_037808735.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_037811530.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_037826920.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_037810228.1 2 Reactome: R-HSA-429958;Reactome: R-HSA-390471 "mRNA decay by 3' to 5' exoribonuclease";"Association of TriC/CCT with target proteins during biosynthesis" XP_037807151.1 8 Reactome: R-HSA-6798695;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724 "Neutrophil degranulation";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Macroautophagy";"Regulation of PTEN gene transcription" XP_037813507.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_037807353.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_037819535.1 17 KEGG: 04926+2.7.11.1;Reactome: R-HSA-8953750;KEGG: 04150+2.7.11.1;Reactome: R-HSA-69601;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-75035;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1433557;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-6804756 "Relaxin signaling pathway";"Transcriptional Regulation by E2F6";"mTOR signaling pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"G2/M DNA damage checkpoint";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Human immunodeficiency virus 1 infection";"Signaling by SCF-KIT";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Human cytomegalovirus infection";"Thermogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Phosphorylation" XP_037828462.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.5 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_037822888.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037818133.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_037825588.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_037824688.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037808562.1 2 Reactome: R-HSA-9020702;Reactome: R-HSA-6798695 "Interleukin-1 signaling";"Neutrophil degranulation" XP_037816181.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_037828100.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_037815225.1 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" XP_037813360.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_037809105.1 12 Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-75893;Reactome: R-HSA-5362798;Reactome: R-HSA-177929;Reactome: R-HSA-193692;Reactome: R-HSA-1251985;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-2644606;Reactome: R-HSA-982772 "Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"TNF signaling";"Release of Hh-Np from the secreting cell";"Signaling by EGFR";"Regulated proteolysis of p75NTR";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Growth hormone receptor signaling" XP_037805841.1 16 Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-176409;Reactome: R-HSA-2559582;Reactome: R-HSA-983168 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037821489.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_037820321.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037823814.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037819501.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_037812082.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_037814819.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037823802.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_037822636.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_037826477.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037811827.1 1 Reactome: R-HSA-350562 "Regulation of ornithine decarboxylase (ODC)" XP_037820770.1 2 Reactome: R-HSA-5693554;Reactome: R-HSA-2564830 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Cytosolic iron-sulfur cluster assembly" XP_037810544.1 8 Reactome: R-HSA-113501;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-68962 "Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation";"Polymerase switching";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex" XP_037813160.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037806391.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037805247.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037805536.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-2408557 "SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis" XP_037811832.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_037816509.1 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" XP_037811631.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_037818656.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_037812469.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037810638.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8875360 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell" XP_037813376.1 2 Reactome: R-HSA-1362409;Reactome: R-HSA-1268020 "Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import" XP_037821496.1 2 Reactome: R-HSA-532668;Reactome: R-HSA-6798695 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation" XP_037822332.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_037822397.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_037815754.1 27 Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-168333;Reactome: R-HSA-4615885 "SUMOylation of SUMOylation proteins";"snRNP Assembly";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins" XP_037824222.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037817334.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_037809046.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037822966.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" XP_037812765.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_037807466.1 6 MetaCyc: PWY-6124;MetaCyc: PWY-7234;KEGG: 00670+2.1.2.3;KEGG: 00230+3.5.4.10+2.1.2.3;Reactome: R-HSA-73817;MetaCyc: PWY-6123 "Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis III";"One carbon pool by folate";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I" XP_037816525.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037807461.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_037819694.1 3 Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation" XP_037809002.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_037819974.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_037810200.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037814090.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037806334.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876 "(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs" XP_037816500.1 2 Reactome: R-HSA-6804756;Reactome: R-HSA-8854518 "Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2" XP_037826589.1 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" XP_037821228.1 4 KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051 "alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Anandamide biosynthesis I" XP_037814341.1 4 Reactome: R-HSA-73817;KEGG: 00250+6.3.4.4;KEGG: 00230+6.3.4.4;MetaCyc: PWY-7219 "Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_037817587.1 5 KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906;Reactome: R-HSA-70171;MetaCyc: PWY-5514;MetaCyc: PWY-6855 "Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Glycolysis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)" XP_037813835.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037820506.1 8 Reactome: R-HSA-8856825;Reactome: R-HSA-5140745;Reactome: R-HSA-432720;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900;Reactome: R-HSA-196025;Reactome: R-HSA-190873 "Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Lysosome Vesicle Biogenesis";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions";"Gap junction degradation" XP_037823451.1 19 Reactome: R-HSA-3000471;Reactome: R-HSA-8964046;Reactome: R-HSA-8963901;Reactome: R-HSA-5686938;Reactome: R-HSA-8964041;Reactome: R-HSA-8957275;Reactome: R-HSA-975634;Reactome: R-HSA-8856828;Reactome: R-HSA-381426;Reactome: R-HSA-8856825;Reactome: R-HSA-3000480;Reactome: R-HSA-432142;Reactome: R-HSA-3000497;Reactome: R-HSA-8964038;Reactome: R-HSA-3000484;Reactome: R-HSA-8866423;Reactome: R-HSA-8964026;Reactome: R-HSA-8963888;Reactome: R-HSA-202733 "Scavenging by Class B Receptors";"VLDL clearance";"Chylomicron remodeling";"Regulation of TLR by endogenous ligand";"LDL remodeling";"Post-translational protein phosphorylation";"Retinoid metabolism and transport";"Clathrin-mediated endocytosis";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"Platelet sensitization by LDL";"Scavenging by Class H Receptors";"LDL clearance";"Scavenging by Class F Receptors";"VLDL assembly";"Chylomicron clearance";"Chylomicron assembly";"Cell surface interactions at the vascular wall" XP_037814450.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_037806329.1 14 MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7619;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7602 "Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_037824961.1 15 Reactome: R-HSA-167246;Reactome: R-HSA-9603505;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-113418 "Tat-mediated elongation of the HIV-1 transcript";"NTRK3 as a dependence receptor";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex" XP_037816304.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_037823124.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037806984.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2 "VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway" XP_037821520.1 42 Reactome: R-HSA-427389;Reactome: R-HSA-2559582;Reactome: R-HSA-3214815;Reactome: R-HSA-2299718;Reactome: R-HSA-3214842;Reactome: R-HSA-2559580;Reactome: R-HSA-2559586;Reactome: R-HSA-8936459;Reactome: R-HSA-110329;Reactome: R-HSA-5334118;Reactome: R-HSA-171306;Reactome: R-HSA-9610379;Reactome: R-HSA-5617472;Reactome: R-HSA-9616222;Reactome: R-HSA-427359;Reactome: R-HSA-3214847;Reactome: R-HSA-912446;Reactome: R-HSA-3214858;Reactome: R-HSA-977225;Reactome: R-HSA-5578749;Reactome: R-HSA-3214841;Reactome: R-HSA-1912408;Reactome: R-HSA-110330;Reactome: R-HSA-73772;Reactome: R-HSA-110328;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-8939236;Reactome: R-HSA-212300;Reactome: R-HSA-201722;Reactome: R-HSA-427413;Reactome: R-HSA-9018519;Reactome: R-HSA-1221632;Reactome: R-HSA-110331;Reactome: R-HSA-606279;Reactome: R-HSA-73728;Reactome: R-HSA-5250924;Reactome: R-HSA-69473;Reactome: R-HSA-5625886;Reactome: R-HSA-5693565 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Senescence-Associated Secretory Phenotype (SASP)";"HDACs deacetylate histones";"Condensation of Prophase Chromosomes";"HDMs demethylate histones";"Oxidative Stress Induced Senescence";"DNA Damage/Telomere Stress Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Cleavage of the damaged pyrimidine";"DNA methylation";"Packaging Of Telomere Ends";"HCMV Late Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of granulopoiesis";"SIRT1 negatively regulates rRNA expression";"HATs acetylate histones";"Meiotic recombination";"RMTs methylate histone arginines";"Amyloid fiber formation";"Transcriptional regulation by small RNAs";"PKMTs methylate histone lysines";"Pre-NOTCH Transcription and Translation";"Recognition and association of DNA glycosylase with site containing an affected purine";"RNA Polymerase I Promoter Escape";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"PRC2 methylates histones and DNA";"Formation of the beta-catenin:TCF transactivating complex";"NoRC negatively regulates rRNA expression";"Estrogen-dependent gene expression";"Meiotic synapsis";"Cleavage of the damaged purine";"Deposition of new CENPA-containing nucleosomes at the centromere";"RNA Polymerase I Promoter Opening";"B-WICH complex positively regulates rRNA expression";"G2/M DNA damage checkpoint";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_037807328.1 3 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-383280 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nuclear Receptor transcription pathway" XP_037826149.1 40 Reactome: R-HSA-8851708;Reactome: R-HSA-203927;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-72203;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-5601884;Reactome: R-HSA-6781823;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-72165;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-73776;Reactome: R-HSA-77075;Reactome: R-HSA-168325;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-6803529;Reactome: R-HSA-5617472;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-6782210;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-72163;Reactome: R-HSA-167246;Reactome: R-HSA-5578749 "Signaling by FGFR2 IIIa TM";"MicroRNA (miRNA) biogenesis";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Minor Pathway";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"Viral Messenger RNA Synthesis";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"FGFR2 alternative splicing";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"mRNA Splicing - Major Pathway";"Tat-mediated elongation of the HIV-1 transcript";"Transcriptional regulation by small RNAs" XP_037820202.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037813099.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037808467.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_037815454.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823 "DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex" XP_037815151.1 4 MetaCyc: PWY-6281;Reactome: R-HSA-2408557;KEGG: 00970+6.1.1.11;Reactome: R-HSA-379716 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_037813742.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037814520.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_037819547.1 14 KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7035 "Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis" XP_037807905.1 18 KEGG: 00250+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-7117;KEGG: 00220+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-5913;MetaCyc: PWY-6638;MetaCyc: PWY-7383;MetaCyc: PWY-7115 "Alanine, aspartate and glutamate metabolism";"Carbon fixation in photosynthetic organisms";"Novobiocin biosynthesis";"Arginine and proline metabolism";"Phenylalanine metabolism";"(R)-cysteate degradation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Arginine biosynthesis";"Cysteine and methionine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Coenzyme M biosynthesis II";"Partial TCA cycle (obligate autotrophs)";"Sulfolactate degradation III";"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" XP_037816086.1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_037827380.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis" XP_037824254.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_037810194.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037810282.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037825963.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037818606.1 7 Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-5083628;Reactome: R-HSA-9010553;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;Reactome: R-HSA-5173105 "ECM proteoglycans";"Non-integrin membrane-ECM interactions";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Regulation of expression of SLITs and ROBOs";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation" XP_037809429.1 9 Reactome: R-HSA-3560801;Reactome: R-HSA-1971475;Reactome: R-HSA-2024096;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;Reactome: R-HSA-975634;Reactome: R-HSA-3560783;Reactome: R-HSA-4420332;Reactome: R-HSA-3656253 "Defective B3GAT3 causes JDSSDHD";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG degradation";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Retinoid metabolism and transport";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS" XP_037821522.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380270 "Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_037823597.1 6 MetaCyc: PWY-6731;Reactome: R-HSA-70221;MetaCyc: PWY-6737;MetaCyc: PWY-7238;MetaCyc: PWY-5941;KEGG: 00500+2.4.1.1 "Starch degradation III";"Glycogen breakdown (glycogenolysis)";"Starch degradation V";"Sucrose biosynthesis II";"Glycogen degradation II";"Starch and sucrose metabolism" XP_037824656.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037818758.1 7 Reactome: R-HSA-373753;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-6798695;Reactome: R-HSA-5673001;Reactome: R-HSA-264870;Reactome: R-HSA-6807878 "Nephrin family interactions";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"Neutrophil degranulation";"RAF/MAP kinase cascade";"Caspase-mediated cleavage of cytoskeletal proteins";"COPI-mediated anterograde transport" XP_037813174.1 2 Reactome: R-HSA-163841;KEGG: 00900+2.1.1.100 "Gamma carboxylation, hypusine formation and arylsulfatase activation";"Terpenoid backbone biosynthesis" XP_037828093.1 2 Reactome: R-HSA-5693554;Reactome: R-HSA-2564830 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Cytosolic iron-sulfur cluster assembly" XP_037816504.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_037815106.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037827072.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_037811738.1 3 Reactome: R-HSA-164843;Reactome: R-HSA-3108214;Reactome: R-HSA-5693571 "2-LTR circle formation";"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)" XP_037808285.1 8 KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Activation of RAC1";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_037810123.1 4 Reactome: R-HSA-73621;MetaCyc: PWY-6963;KEGG: 00910+1.4.1.14;KEGG: 00250+1.4.1.14 "Pyrimidine catabolism";"Ammonia assimilation cycle I";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism" XP_037817545.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_037822658.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_037821476.1 5 Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-983170 "Cargo concentration in the ER";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" XP_037813466.1 5 Reactome: R-HSA-936964;Reactome: R-HSA-936440;Reactome: R-HSA-933541;Reactome: R-HSA-9013973;Reactome: R-HSA-918233 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Negative regulators of DDX58/IFIH1 signaling";"TRAF6 mediated IRF7 activation";"TICAM1-dependent activation of IRF3/IRF7";"TRAF3-dependent IRF activation pathway" XP_037822969.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_037816507.1 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" XP_037813109.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037816090.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_037821268.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037806390.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037811606.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_037807480.1 5 MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-7822 "Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)" XP_037827957.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_037825421.1 5 Reactome: R-HSA-8873719;Reactome: R-HSA-1660499;Reactome: R-HSA-1445148;Reactome: R-HSA-8876198;Reactome: R-HSA-6798695 "RAB geranylgeranylation";"Synthesis of PIPs at the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RAB GEFs exchange GTP for GDP on RABs";"Neutrophil degranulation" XP_037819827.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_037805498.1 4 KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922;MetaCyc: PWY-5737;Reactome: R-HSA-70688 "Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism" XP_037824552.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_037819602.1 2 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_037822535.1 12 MetaCyc: PWY-5871;MetaCyc: PWY-5872;Reactome: R-HSA-2142789;MetaCyc: PWY-7233;MetaCyc: PWY-5855;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-7230;MetaCyc: PWY-5856;MetaCyc: PWY-5873;MetaCyc: PWY-5870;MetaCyc: PWY-5857;MetaCyc: PWY-6708 "Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)" XP_037818515.1 7 Reactome: R-HSA-2151201;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1268020;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Transcriptional activation of mitochondrial biogenesis";"Oxidative phosphorylation";"Mitochondrial protein import";"Photosynthesis";"ATP biosynthesis";"Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_037817562.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_037808511.1 6 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_037813113.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037815456.1 6 Reactome: R-HSA-3371599;Reactome: R-HSA-196780;MetaCyc: PWY-7382;KEGG: 00780+6.3.4.15;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987 "Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)" XP_037827376.1 4 KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48 "Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism" XP_037812412.1 6 Reactome: R-HSA-1442490;Reactome: R-HSA-3000171;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-8874081;Reactome: R-HSA-2022090 "Collagen degradation";"Non-integrin membrane-ECM interactions";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures" XP_037819072.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037812394.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037821839.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037815246.1 13 KEGG: 00720+4.2.1.2;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-5913;MetaCyc: PWY-8086;KEGG: 00620+4.2.1.2;MetaCyc: PWY-6969;MetaCyc: PWY-7384;KEGG: 00020+4.2.1.2;MetaCyc: PWY-7254;Reactome: R-HSA-71403;MetaCyc: PWY-561;MetaCyc: PWY-5392 "Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Reductive TCA cycle II" XP_037807277.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037826622.1 5 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-6811440;Reactome: R-HSA-204005 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport" XP_037813053.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037819726.1 14 MetaCyc: PWY-6453;MetaCyc: PWY-8055;MetaCyc: PWY-7782;Reactome: R-HSA-1483191;Reactome: R-HSA-4419969;MetaCyc: PWY-8053;KEGG: 00565+3.1.3.4;Reactome: R-HSA-75109;MetaCyc: PWY-8052;KEGG: 00561+3.1.3.4;KEGG: 00564+3.1.3.4;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8051;Reactome: R-HSA-1483213 "Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Synthesis of PC";"Depolymerisation of the Nuclear Lamina";"Anandamide biosynthesis II";"Ether lipid metabolism";"Triglyceride biosynthesis";"2-arachidonoylglycerol biosynthesis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Sphingolipid metabolism";"Anandamide biosynthesis I";"Synthesis of PE" XP_037826728.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_037806256.1 3 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.14;Reactome: R-HSA-379716 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_037807010.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_037807463.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037820737.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037816393.1 3 KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3 "Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis" XP_037828275.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_037805425.1 10 KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00051+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1861 "Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)";"Galactose metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" XP_037807816.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-5205685 "Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy" XP_037823542.1 42 Reactome: R-HSA-69473;Reactome: R-HSA-5250924;Reactome: R-HSA-73728;Reactome: R-HSA-5693565;Reactome: R-HSA-5625886;Reactome: R-HSA-110331;Reactome: R-HSA-1221632;Reactome: R-HSA-606279;Reactome: R-HSA-427413;Reactome: R-HSA-201722;Reactome: R-HSA-212300;Reactome: R-HSA-8939236;Reactome: R-HSA-4551638;Reactome: R-HSA-9018519;Reactome: R-HSA-73772;Reactome: R-HSA-9609690;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-110328;Reactome: R-HSA-977225;Reactome: R-HSA-5578749;Reactome: R-HSA-3214858;Reactome: R-HSA-110330;Reactome: R-HSA-3214841;Reactome: R-HSA-1912408;Reactome: R-HSA-427359;Reactome: R-HSA-9616222;Reactome: R-HSA-3214847;Reactome: R-HSA-5617472;Reactome: R-HSA-912446;Reactome: R-HSA-171306;Reactome: R-HSA-5334118;Reactome: R-HSA-9610379;Reactome: R-HSA-3214815;Reactome: R-HSA-2559582;Reactome: R-HSA-427389;Reactome: R-HSA-110329;Reactome: R-HSA-2559586;Reactome: R-HSA-8936459;Reactome: R-HSA-2559580;Reactome: R-HSA-3214842;Reactome: R-HSA-2299718 "G2/M DNA damage checkpoint";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Opening";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Cleavage of the damaged purine";"Meiotic synapsis";"Deposition of new CENPA-containing nucleosomes at the centromere";"NoRC negatively regulates rRNA expression";"Formation of the beta-catenin:TCF transactivating complex";"PRC2 methylates histones and DNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SUMOylation of chromatin organization proteins";"Estrogen-dependent gene expression";"RNA Polymerase I Promoter Escape";"HCMV Early Events";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Amyloid fiber formation";"Transcriptional regulation by small RNAs";"RMTs methylate histone arginines";"Recognition and association of DNA glycosylase with site containing an affected purine";"PKMTs methylate histone lysines";"Pre-NOTCH Transcription and Translation";"SIRT1 negatively regulates rRNA expression";"Transcriptional regulation of granulopoiesis";"HATs acetylate histones";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Meiotic recombination";"Packaging Of Telomere Ends";"DNA methylation";"HCMV Late Events";"HDACs deacetylate histones";"Senescence-Associated Secretory Phenotype (SASP)";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Cleavage of the damaged pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Oxidative Stress Induced Senescence";"HDMs demethylate histones";"Condensation of Prophase Chromosomes" XP_037813521.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-174490 "Late endosomal microautophagy";"Budding and maturation of HIV virion";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins" XP_037825745.1 5 MetaCyc: PWY-6012;MetaCyc: PWY-6012-1;MetaCyc: PWY-6289;Reactome: R-HSA-199220;KEGG: 00770+2.7.8.7 "Acyl carrier protein metabolism";"Acyl carrier protein activation";"Petrobactin biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Pantothenate and CoA biosynthesis" XP_037809501.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_037814911.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037812928.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037816068.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037820040.1 1 Reactome: R-HSA-5635838 "Activation of SMO" XP_037815600.1 12 KEGG: 00561+2.7.7.9;KEGG: 00500+2.7.7.9;KEGG: 00040+2.7.7.9;KEGG: 00052+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-7238;MetaCyc: PWY-6527;MetaCyc: PWY-7817;Reactome: R-HSA-3322077;MetaCyc: PWY-7343;KEGG: 00520+2.7.7.9;Reactome: R-HSA-173599 "Glycerolipid metabolism";"Starch and sucrose metabolism";"Pentose and glucuronate interconversions";"Galactose metabolism";"Sucrose degradation II (sucrose synthase)";"Sucrose biosynthesis II";"Stachyose degradation";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycogen synthesis";"UDP-alpha-D-glucose biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate" XP_037812408.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-75953 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation" XP_037817374.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037809915.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_037823332.1 4 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"DARPP-32 events" XP_037828624.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_037813335.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" XP_037813223.1 10 Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-451308;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-447038 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Activation of Ca-permeable Kainate Receptor";"Synaptic adhesion-like molecules";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"NrCAM interactions" XP_037828656.1 8 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 05163+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Human cytomegalovirus infection" XP_037822102.1 3 MetaCyc: PWY-5698;MetaCyc: PWY-5697;KEGG: 00230+3.5.2.5 "Allantoin degradation to ureidoglycolate II (ammonia producing)";"Allantoin degradation to ureidoglycolate I (urea producing)";"Purine metabolism" XP_037813161.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037812570.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_037816700.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_037807869.1 9 MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.8;MetaCyc: PWY-6118;MetaCyc: PWY-7385;MetaCyc: PWY-5667;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7902 "CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"1,3-propanediol biosynthesis (engineered)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis" XP_037812740.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_037810085.1 4 MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6902 "Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)" XP_037812275.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037827089.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_037817703.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_037812374.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037827098.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037807910.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_037816246.1 5 KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I" XP_037806829.1 15 Reactome: R-HSA-2559582;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-174154 "Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin" XP_037823196.1 6 Reactome: R-HSA-381426;Reactome: R-HSA-2173796;Reactome: R-HSA-201722;Reactome: R-HSA-8957275;Reactome: R-HSA-3769402;Reactome: R-HSA-5626467 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of the beta-catenin:TCF transactivating complex";"Post-translational protein phosphorylation";"Deactivation of the beta-catenin transactivating complex";"RHO GTPases activate IQGAPs" XP_037828612.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037813675.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037810537.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_037809958.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037816769.1 4 MetaCyc: PWY-7375;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-72086 "Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping" XP_037818078.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_037812468.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037817389.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_037824994.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037813592.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_037821887.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_037809401.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037815498.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037821741.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037821769.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037817278.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037817742.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_037824886.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_037818803.1 6 Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-77588;Reactome: R-HSA-72165;Reactome: R-HSA-111367;Reactome: R-HSA-73856 "snRNP Assembly";"mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination" XP_037809663.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_037817375.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037821606.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72702 "Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition" XP_037817439.1 2 Reactome: R-HSA-2022928;MetaCyc: PWY-6558 "HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)" XP_037826841.1 2 MetaCyc: PWY-5905;Reactome: R-HSA-204626 "Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine" XP_037813790.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_037822920.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037806257.1 3 KEGG: 00970+6.1.1.14;Reactome: R-HSA-379726;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation" XP_037806144.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_037808914.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037820508.1 1 Reactome: R-HSA-1483101 "Synthesis of PS" XP_037826024.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037807330.1 3 Reactome: R-HSA-383280;Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "Nuclear Receptor transcription pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_037815551.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_037816022.1 2 Reactome: R-HSA-8953750;Reactome: R-HSA-8939243 "Transcriptional Regulation by E2F6";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_037815599.1 12 MetaCyc: PWY-6527;MetaCyc: PWY-7238;MetaCyc: PWY-7817;Reactome: R-HSA-3322077;Reactome: R-HSA-173599;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7343;KEGG: 00561+2.7.7.9;KEGG: 00040+2.7.7.9;KEGG: 00500+2.7.7.9;KEGG: 00052+2.7.7.9;MetaCyc: PWY-3801 "Stachyose degradation";"Sucrose biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycogen synthesis";"Formation of the active cofactor, UDP-glucuronate";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucose biosynthesis I";"Glycerolipid metabolism";"Pentose and glucuronate interconversions";"Starch and sucrose metabolism";"Galactose metabolism";"Sucrose degradation II (sucrose synthase)" XP_037825677.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037827610.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942 "Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition" XP_037812048.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_037825622.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037823456.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_037805921.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_037823677.1 7 MetaCyc: PWY-7511;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-3108214;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-983168 "Protein ubiquitination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037807379.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037820884.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_037810086.1 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_037812774.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_037810007.1 13 Reactome: R-HSA-1442490;Reactome: R-HSA-419037;Reactome: R-HSA-186797;Reactome: R-HSA-8948216;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-2214320;Reactome: R-HSA-2243919;Reactome: R-HSA-1474244;Reactome: R-HSA-216083;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-3000157 "Collagen degradation";"NCAM1 interactions";"Signaling by PDGF";"Collagen chain trimerization";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"Anchoring fibril formation";"Crosslinking of collagen fibrils";"Extracellular matrix organization";"Integrin cell surface interactions";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Laminin interactions" XP_037822499.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037824393.1 7 MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-5469 "Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis" XP_037808236.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-1799339 "Peptide chain elongation";"Viral mRNA Translation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane" XP_037814419.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_037822099.1 9 KEGG: 00710+1.2.1.12;MetaCyc: PWY-8004;Reactome: R-HSA-70171;Reactome: R-HSA-70263;MetaCyc: PWY-7003;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00010+1.2.1.12;MetaCyc: PWY-6901 "Carbon fixation in photosynthetic organisms";"Entner-Doudoroff pathway I";"Glycolysis";"Gluconeogenesis";"Glycerol degradation to butanol";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation" XP_037822534.1 12 MetaCyc: PWY-5870;MetaCyc: PWY-5857;MetaCyc: PWY-6708;MetaCyc: PWY-5873;MetaCyc: PWY-7230;MetaCyc: PWY-5856;MetaCyc: PWY-5871;MetaCyc: PWY-5872;Reactome: R-HSA-2142789;MetaCyc: PWY-7233;MetaCyc: PWY-5855;KEGG: 00130+2.1.1.222+2.1.1.64 "Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_037819862.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_037823650.1 6 Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-418592 "Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1" XP_037807824.1 7 Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948 "NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_037821501.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037827826.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037813965.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037811000.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037815295.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-419812 "G alpha (s) signalling events";"Calcitonin-like ligand receptors" XP_037805893.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037805961.1 6 Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;MetaCyc: PWY-7511;Reactome: R-HSA-6782210 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Protein ubiquitination";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_037819241.1 5 Reactome: R-HSA-5689877;Reactome: R-HSA-977225;Reactome: R-HSA-5205685;Reactome: R-HSA-9646399;Reactome: R-HSA-983168 "Josephin domain DUBs";"Amyloid fiber formation";"Pink/Parkin Mediated Mitophagy";"Aggrephagy";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037805721.1 4 MetaCyc: PWY-7887;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.12;MetaCyc: PWY-6823 "Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" XP_037814694.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037805727.1 4 MetaCyc: PWY-7221;KEGG: 00230+6.3.5.2;KEGG: 00983+6.3.5.2;Reactome: R-HSA-73817 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis" XP_037814247.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_037826288.1 7 MetaCyc: PWY-6363;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.25;KEGG: 00562+3.1.3.25;KEGG: 00521+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-4702 "D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"Phytate degradation I" XP_037811260.1 3 Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942 "Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)" XP_037826850.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_037819703.1 20 MetaCyc: PWY-7858;MetaCyc: PWY-7726;MetaCyc: PWY-7340;MetaCyc: PWY-735;MetaCyc: PWY-7337;MetaCyc: PWY-5136;MetaCyc: PWY-6837;MetaCyc: PWY-7288;MetaCyc: PWY-6920;KEGG: 00071+1.3.3.6;KEGG: 00592+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7606;MetaCyc: PWY-7338;Reactome: R-HSA-9033241;MetaCyc: PWY-7574;MetaCyc: PWY-7854;MetaCyc: PWY-7007;KEGG: 00410+1.3.3.6 "(5Z)-dodecenoate biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"Propanoate metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Peroxisomal protein import";"Propanoyl-coa degradation II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"beta-Alanine metabolism" XP_037818537.1 4 Reactome: R-HSA-6799198;Reactome: R-HSA-77289;Reactome: R-HSA-389661;Reactome: R-HSA-611105 "Complex I biogenesis";"Mitochondrial Fatty Acid Beta-Oxidation";"Glyoxylate metabolism and glycine degradation";"Respiratory electron transport" XP_037809565.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037812639.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_037812115.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689 "Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits" XP_037819611.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037813629.1 5 Reactome: R-HSA-5579006;Reactome: R-HSA-174403;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3;KEGG: 00270+6.3.2.3 "Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Glutathione metabolism";"Cysteine and methionine metabolism" XP_037825144.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_037824682.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037807265.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037819982.1 5 Reactome: R-HSA-8963693;Reactome: R-HSA-9648895;Reactome: R-HSA-9633012;KEGG: 00250+6.3.5.4;Reactome: R-HSA-380994 "Aspartate and asparagine metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Alanine, aspartate and glutamate metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_037817456.1 20 Reactome: R-HSA-9033241;MetaCyc: PWY-7854;MetaCyc: PWY-7574;MetaCyc: PWY-7007;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7291;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7288;MetaCyc: PWY-6920;KEGG: 00592+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7337;MetaCyc: PWY-5136;MetaCyc: PWY-6837;MetaCyc: PWY-7340;MetaCyc: PWY-7858;MetaCyc: PWY-7726 "Peroxisomal protein import";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoyl-coa degradation II";"Methyl ketone biosynthesis (engineered)";"beta-Alanine metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"6-gingerol analog biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"Jasmonic acid biosynthesis";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)" XP_037805585.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037805421.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037817542.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-5627123 "Clathrin-mediated endocytosis";"RHO GTPases activate PAKs" XP_037818925.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_037808682.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037815536.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037816706.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037807411.1 14 Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7035 "Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis" XP_037828682.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_037806733.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_037826641.1 6 Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_037806237.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_037805829.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037813264.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_037821138.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_037819484.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_037806349.1 14 MetaCyc: PWY-7619;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7036 "Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II" XP_037805885.1 5 MetaCyc: PWY-7082;KEGG: 00190+7.1.1.8;MetaCyc: PWY-3781;MetaCyc: PWY-7279;MetaCyc: PWY-6692 "Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Fe(II) oxidation" XP_037806352.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7619;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199 "(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation" XP_037813859.1 2 Reactome: R-HSA-8853659;Reactome: R-HSA-5673001 "RET signaling";"RAF/MAP kinase cascade" XP_037805884.1 5 MetaCyc: PWY-6692;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7279;MetaCyc: PWY-3781;MetaCyc: PWY-7082 "Fe(II) oxidation";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"Ammonia oxidation IV (autotrophic ammonia oxidizers)" XP_037816508.1 2 Reactome: R-HSA-8854518;Reactome: R-HSA-6804756 "AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation" XP_037806285.1 3 MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217 "Adenine and adenosine salvage VI";"Purine metabolism";"Purine salvage" XP_037817145.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-2408557 "SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis" XP_037819423.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_037823936.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_037806478.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis" XP_037810897.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037808746.1 9 MetaCyc: PWY-6142;MetaCyc: PWY-241;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;Reactome: R-HSA-1475029;MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-5743 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"3-hydroxypropanoate cycle" XP_037815579.1 56 Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-2871837;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761 "Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"FCERI mediated NF-kB activation";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling" XP_037805647.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase" XP_037817281.1 9 KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-416476;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367 "Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism" XP_037810476.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467 "Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs" XP_037811208.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037826518.1 8 Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-3371571 "Macroautophagy";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"TP53 Regulates Metabolic Genes";"HSF1-dependent transactivation" XP_037821226.1 4 MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32 "Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism" XP_037818759.1 7 Reactome: R-HSA-6807878;Reactome: R-HSA-6798695;Reactome: R-HSA-5673001;Reactome: R-HSA-264870;Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-373753 "COPI-mediated anterograde transport";"Neutrophil degranulation";"RAF/MAP kinase cascade";"Caspase-mediated cleavage of cytoskeletal proteins";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"Nephrin family interactions" XP_037813952.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037807959.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72764 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination" XP_037817219.1 9 MetaCyc: PWY-6146;MetaCyc: PWY-6142;Reactome: R-HSA-196780;MetaCyc: PWY-8086;KEGG: 00720+6.4.1.1;Reactome: R-HSA-70263;KEGG: 00020+6.4.1.1;Reactome: R-HSA-3371599;KEGG: 00620+6.4.1.1 "Methanobacterium thermoautotrophicum biosynthetic metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Biotin transport and metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis";"Citrate cycle (TCA cycle)";"Defective HLCS causes multiple carboxylase deficiency";"Pyruvate metabolism" XP_037817186.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037821765.1 44 Reactome: R-HSA-9634638;Reactome: R-HSA-6802948;Reactome: R-HSA-450341;Reactome: R-HSA-6802955;Reactome: R-HSA-162658;Reactome: R-HSA-3371453;KEGG: 04150+2.7.11.24;Reactome: R-HSA-9635465;Reactome: R-HSA-8939211;Reactome: R-HSA-170968;Reactome: R-HSA-982772;Reactome: R-HSA-2871796;Reactome: R-HSA-6802946;Reactome: R-HSA-2029482;Reactome: R-HSA-879415;Reactome: R-HSA-9649948;Reactome: R-HSA-375165;Reactome: R-HSA-198753;Reactome: R-HSA-5673001;Reactome: R-HSA-8943724;Reactome: R-HSA-445144;Reactome: R-HSA-5654727;Reactome: R-HSA-5668599;Reactome: R-HSA-9627069;Reactome: R-HSA-112409;Reactome: R-HSA-5654732;Reactome: R-HSA-5675221;Reactome: R-HSA-456926;Reactome: R-HSA-6802952;Reactome: R-HSA-5674499;Reactome: R-HSA-1295596;Reactome: R-HSA-6811558;Reactome: R-HSA-5674135;Reactome: R-HSA-5654726;Reactome: R-HSA-202670;Reactome: R-HSA-444257;Reactome: R-HSA-74749;Reactome: R-HSA-5654733;Reactome: R-HSA-5663213;Reactome: R-HSA-2559582;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-8940973;Reactome: R-HSA-881907 "Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Signaling by high-kinase activity BRAF mutants";"Activation of the AP-1 family of transcription factors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Golgi Cisternae Pericentriolar Stack Reorganization";"Regulation of HSF1-mediated heat shock response";"mTOR signaling pathway";"Suppression of apoptosis";"ESR-mediated signaling";"Frs2-mediated activation";"Growth hormone receptor signaling";"FCERI mediated MAPK activation";"Signaling by moderate kinase activity BRAF mutants";"Regulation of actin dynamics for phagocytic cup formation";"Advanced glycosylation endproduct receptor signaling";"Signaling downstream of RAS mutants";"NCAM signaling for neurite out-growth";"ERK/MAPK targets";"RAF/MAP kinase cascade";"Regulation of PTEN gene transcription";"Signal transduction by L1";"Negative regulation of FGFR2 signaling";"RHO GTPases Activate NADPH Oxidases";"Regulation of the apoptosome activity";"RAF-independent MAPK1/3 activation";"Negative regulation of FGFR3 signaling";"Negative regulation of MAPK pathway";"Thrombin signalling through proteinase activated receptors (PARs)";"Signaling by BRAF and RAF fusions";"Negative feedback regulation of MAPK pathway";"Spry regulation of FGF signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"MAP2K and MAPK activation";"Negative regulation of FGFR1 signaling";"ERKs are inactivated";"RSK activation";"Signal attenuation";"Negative regulation of FGFR4 signaling";"RHO GTPases Activate WASPs and WAVEs";"Senescence-Associated Secretory Phenotype (SASP)";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"RUNX2 regulates osteoblast differentiation";"Gastrin-CREB signalling pathway via PKC and MAPK" XP_037806866.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" XP_037827094.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase" XP_037811149.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-427413 "HATs acetylate histones";"NoRC negatively regulates rRNA expression" XP_037813772.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646 "Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification" XP_037810623.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" XP_037807565.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037806457.1 5 Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_037814310.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_037812840.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_037812387.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037808608.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers" XP_037806463.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" XP_037819497.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_037805438.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_037809988.1 5 KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-197264;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108 "Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_037813377.1 3 MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740 "Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors" XP_037807377.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037826838.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_037820233.1 2 KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668 "Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_037822166.1 10 Reactome: R-HSA-442742;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-437239;Reactome: R-HSA-444257;KEGG: 04714+2.7.11.1 "CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Recycling pathway of L1";"RSK activation";"Thermogenesis" XP_037817213.1 42 Reactome: R-HSA-5334118;Reactome: R-HSA-171306;Reactome: R-HSA-9610379;Reactome: R-HSA-2559582;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-3214842;Reactome: R-HSA-2299718;Reactome: R-HSA-110329;Reactome: R-HSA-2559586;Reactome: R-HSA-8936459;Reactome: R-HSA-2559580;Reactome: R-HSA-3214858;Reactome: R-HSA-5578749;Reactome: R-HSA-977225;Reactome: R-HSA-110330;Reactome: R-HSA-3214841;Reactome: R-HSA-1912408;Reactome: R-HSA-3214847;Reactome: R-HSA-427359;Reactome: R-HSA-9616222;Reactome: R-HSA-5617472;Reactome: R-HSA-912446;Reactome: R-HSA-201722;Reactome: R-HSA-212300;Reactome: R-HSA-8939236;Reactome: R-HSA-4551638;Reactome: R-HSA-427413;Reactome: R-HSA-9018519;Reactome: R-HSA-73772;Reactome: R-HSA-110328;Reactome: R-HSA-9609690;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-73728;Reactome: R-HSA-69473;Reactome: R-HSA-5250924;Reactome: R-HSA-5625886;Reactome: R-HSA-5693565;Reactome: R-HSA-110331;Reactome: R-HSA-1221632;Reactome: R-HSA-606279 "DNA methylation";"Packaging Of Telomere Ends";"HCMV Late Events";"Senescence-Associated Secretory Phenotype (SASP)";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDMs demethylate histones";"Condensation of Prophase Chromosomes";"Cleavage of the damaged pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Oxidative Stress Induced Senescence";"RMTs methylate histone arginines";"Transcriptional regulation by small RNAs";"Amyloid fiber formation";"Recognition and association of DNA glycosylase with site containing an affected purine";"PKMTs methylate histone lysines";"Pre-NOTCH Transcription and Translation";"HATs acetylate histones";"SIRT1 negatively regulates rRNA expression";"Transcriptional regulation of granulopoiesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Meiotic recombination";"Formation of the beta-catenin:TCF transactivating complex";"PRC2 methylates histones and DNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SUMOylation of chromatin organization proteins";"NoRC negatively regulates rRNA expression";"Estrogen-dependent gene expression";"RNA Polymerase I Promoter Escape";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HCMV Early Events";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"RNA Polymerase I Promoter Opening";"G2/M DNA damage checkpoint";"B-WICH complex positively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cleavage of the damaged purine";"Meiotic synapsis";"Deposition of new CENPA-containing nucleosomes at the centromere" XP_037812726.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_037824757.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037817273.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037810743.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037812392.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037823820.1 3 Reactome: R-HSA-4085001;MetaCyc: PWY-1269;KEGG: 00540+2.7.7.38 "Sialic acid metabolism";"CMP-3-deoxy-D-manno-octulosonate biosynthesis";"Lipopolysaccharide biosynthesis" XP_037825523.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037806344.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876 "(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs" XP_037827004.1 4 KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2 "Lysine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism" XP_037820488.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037813846.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037811028.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037821115.1 6 Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107 "Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" XP_037819132.1 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" XP_037814294.1 6 MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067;Reactome: R-HSA-189085;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900 "Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)" XP_037817471.1 13 KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7883 "Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"Anhydromuropeptides recycling II" XP_037823229.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037823800.1 4 Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-381771 "Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" XP_037816243.1 5 MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16 "CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism" XP_037816687.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_037808600.1 3 Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_037819969.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037817779.1 8 Reactome: R-HSA-9639288;Reactome: R-HSA-983712;MetaCyc: PWY-7980;Reactome: R-HSA-77387;Reactome: R-HSA-917977;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1222556 "Amino acids regulate mTORC1";"Ion channel transport";"ATP biosynthesis";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Photosynthesis";"Oxidative phosphorylation";"ROS and RNS production in phagocytes" XP_037817239.1 3 KEGG: 00130+1.17.4.4;MetaCyc: PWY-7999;Reactome: R-HSA-6806664 "Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle";"Metabolism of vitamin K" XP_037822993.1 8 MetaCyc: PWY-5;KEGG: 00250+4.3.2.1;MetaCyc: PWY-7400;Reactome: R-HSA-70635;MetaCyc: PWY-4984;KEGG: 00220+4.3.2.1;MetaCyc: PWY-5154;MetaCyc: PWY-4983 "Canavanine biosynthesis";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis IV (archaebacteria)";"Urea cycle";"Urea cycle";"Arginine biosynthesis";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Nitric oxide biosynthesis II (mammals)" XP_037821850.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037815567.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037814587.1 5 Reactome: R-HSA-5221030;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-110328 "TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" XP_037815885.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037814846.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_037811298.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037810521.1 11 MetaCyc: PWY-6549;KEGG: 00020+1.1.1.42;MetaCyc: PWY-5913;MetaCyc: PWY-7268;MetaCyc: PWY-6728;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7124;MetaCyc: PWY-6969;MetaCyc: PWY-7254;KEGG: 00720+1.1.1.42;Reactome: R-HSA-71403 "L-glutamine biosynthesis III";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Methylaspartate cycle";"Glutathione metabolism";"Ethylene biosynthesis V (engineered)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)" XP_037827410.1 3 KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317 "Glycolysis / Gluconeogenesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)" XP_037822036.1 18 KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-7409;Reactome: R-HSA-1483166;MetaCyc: PWY-7416;Reactome: R-HSA-1482839;MetaCyc: PWY-7783;Reactome: R-HSA-1482922;KEGG: 00592+3.1.1.4 "Linoleic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Arachidonic acid metabolism";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Synthesis of PA";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PE";"Plasmalogen degradation";"Acyl chain remodelling of PI";"alpha-Linolenic acid metabolism" XP_037820192.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037828689.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037807305.1 2 Reactome: R-HSA-3371599;Reactome: R-HSA-196780 "Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism" XP_037810747.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-1268020 "Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import" XP_037811404.1 2 Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13 "Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system" XP_037806479.1 7 KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway" XP_037807558.1 4 Reactome: R-HSA-3000170;Reactome: R-HSA-216083;Reactome: R-HSA-2129379;Reactome: R-HSA-3000178 "Syndecan interactions";"Integrin cell surface interactions";"Molecules associated with elastic fibres";"ECM proteoglycans" XP_037808559.1 7 Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;MetaCyc: PWY-7511 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Protein ubiquitination" XP_037809566.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037814087.1 12 KEGG: 00010+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-7385;KEGG: 00051+4.1.2.13;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1861;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00710+4.1.2.13 "Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Methane metabolism";"Gluconeogenesis";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms" XP_037816310.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037820101.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_037825351.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_037805424.1 10 MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00051+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1861;KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-7385 "Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Methane metabolism";"Galactose metabolism";"1,3-propanediol biosynthesis (engineered)" XP_037824343.1 8 MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;Reactome: R-HSA-6798695;MetaCyc: PWY-6609;Reactome: R-HSA-5683826;KEGG: 00230+3.5.4.4;MetaCyc: PWY-6611;MetaCyc: PWY-7179 "Purine deoxyribonucleosides degradation II";"Purine salvage";"Neutrophil degranulation";"Adenine and adenosine salvage III";"Surfactant metabolism";"Purine metabolism";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation I" XP_037810906.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_037812458.1 3 Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1 "Aspartate and asparagine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism" XP_037824429.1 5 Reactome: R-HSA-5658442;Reactome: R-HSA-8849471;Reactome: R-HSA-5218921;Reactome: R-HSA-186763;Reactome: R-HSA-3928662 "Regulation of RAS by GAPs";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"VEGFR2 mediated cell proliferation";"Downstream signal transduction";"EPHB-mediated forward signaling" XP_037807731.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037806252.1 11 Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-432040 "Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"PKA activation";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Purine metabolism";"Hedgehog 'off' state";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_037813627.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_037812179.1 3 KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894 "Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation" XP_037805827.1 13 Reactome: R-HSA-2024101;MetaCyc: PWY-7883;Reactome: R-HSA-2022857;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52 "CS/DS degradation";"Anhydromuropeptides recycling II";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation" XP_037812728.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_037826486.1 1 Reactome: R-HSA-72731 "Recycling of eIF2:GDP" XP_037811027.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037809410.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037808603.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers" XP_037818632.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" XP_037815072.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689 "Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits" XP_037827835.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_037808407.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_037806327.1 14 MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7035;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7602 "Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_037817208.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037806555.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037824120.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_037820431.1 1 Reactome: R-HSA-2565942 "Regulation of PLK1 Activity at G2/M Transition" XP_037806617.1 13 Reactome: R-HSA-5358346;Reactome: R-HSA-532668;Reactome: R-HSA-9646399;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-5689877;Reactome: R-HSA-5689896;Reactome: R-HSA-8866654;Reactome: R-HSA-8876725;Reactome: R-HSA-382556;Reactome: R-HSA-3371511;Reactome: R-HSA-110320;Reactome: R-HSA-5362768 "Hedgehog ligand biogenesis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Aggrephagy";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"Josephin domain DUBs";"Ovarian tumor domain proteases";"E3 ubiquitin ligases ubiquitinate target proteins";"Protein methylation";"ABC-family proteins mediated transport";"HSF1 activation";"Translesion Synthesis by POLH";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_037824987.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_037810691.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_037819035.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_037813197.1 2 Reactome: R-HSA-8849473;Reactome: R-HSA-6791226 "PTK6 Expression";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037820635.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037811186.1 5 Reactome: R-HSA-6811440;Reactome: R-HSA-8856825;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828;Reactome: R-HSA-432722 "Retrograde transport at the Trans-Golgi-Network";"Cargo recognition for clathrin-mediated endocytosis";"Neutrophil degranulation";"Clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis" XP_037809668.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037816834.1 5 Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"Cargo concentration in the ER";"COPII-mediated vesicle transport" XP_037816841.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037817381.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037822952.1 6 Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-210500 "Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle" XP_037813791.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_037815335.1 6 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_037812554.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037806321.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_037824957.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_037815660.1 4 Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-422085 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin" XP_037827182.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_037816505.1 2 Reactome: R-HSA-163282;Reactome: R-HSA-2151201 "Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis" XP_037810770.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_037814155.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037816176.1 14 Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-113418 "Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex" XP_037805709.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_037820960.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_037828296.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037826987.1 6 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_037814591.1 5 Reactome: R-HSA-110328;Reactome: R-HSA-3108214;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-5221030 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA" XP_037806942.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_037808347.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037822765.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_037825976.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_037807543.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_037815856.1 4 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes" XP_037806764.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection" XP_037813239.1 10 Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-451308;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-447038;Reactome: R-HSA-9609736 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Activation of Ca-permeable Kainate Receptor";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Synaptic adhesion-like molecules";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"NrCAM interactions";"Assembly and cell surface presentation of NMDA receptors" XP_037809692.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_037821322.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_037808701.1 33 Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-180910;Reactome: R-HSA-9648025;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-3232142;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-68877;Reactome: R-HSA-159236;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-2467813;Reactome: R-HSA-168333;Reactome: R-HSA-2500257;Reactome: R-HSA-191859;Reactome: R-HSA-141444;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-5663220;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-4570464 "SUMOylation of SUMOylation proteins";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Vpr-mediated nuclear import of PICs";"EML4 and NUDC in mitotic spindle formation";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of ubiquitinylation proteins";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"Mitotic Prometaphase";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Separation of Sister Chromatids";"NEP/NS2 Interacts with the Cellular Export Machinery";"Resolution of Sister Chromatid Cohesion";"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"RHO GTPases Activate Formins";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins" XP_037814362.1 56 Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-68949;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-5689603;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-174154;Reactome: R-HSA-2871837;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-69017;Reactome: R-HSA-202424;Reactome: R-HSA-450408 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"UCH proteinases";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"APC/C:Cdc20 mediated degradation of Securin";"FCERI mediated NF-kB activation";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA" XP_037818104.1 4 MetaCyc: PWY-5041;Reactome: R-HSA-156581;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912 "S-adenosyl-L-methionine cycle II";"Methylation";"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis" XP_037817385.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037806305.1 4 KEGG: 00790+2.8.1.12;Reactome: R-HSA-947581;MetaCyc: PWY-7887;MetaCyc: PWY-6823 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis" XP_037818317.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_037819573.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_037812037.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_037810052.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037812990.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037805419.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037820362.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_037819406.1 6 Reactome: R-HSA-173599;KEGG: 00053+1.1.1.22;KEGG: 00040+1.1.1.22;MetaCyc: PWY-7346;KEGG: 00520+1.1.1.22;MetaCyc: PWY-7820 "Formation of the active cofactor, UDP-glucuronate";"Ascorbate and aldarate metabolism";"Pentose and glucuronate interconversions";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Amino sugar and nucleotide sugar metabolism";"Teichuronic acid biosynthesis (B. subtilis 168)" XP_037823401.1 2 Reactome: R-HSA-212676;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_037828294.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037821442.1 19 Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-5673000;Reactome: R-HSA-5673001;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-936837 "Interferon gamma signaling";"HSF1-dependent transactivation";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"RAF activation";"RAF/MAP kinase cascade";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion transport by P-type ATPases" XP_037809569.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037812215.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037828196.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037805520.1 3 Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007 "Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy" XP_037808361.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037810338.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_037808954.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037811746.1 5 Reactome: R-HSA-964975;KEGG: 00750+2.7.1.35;MetaCyc: PWY-7282;Reactome: R-HSA-6798695;MetaCyc: PWY-7204 "Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Neutrophil degranulation";"Pyridoxal 5'-phosphate salvage II (plants)" XP_037821086.1 7 KEGG: 00190+7.1.2.2;Reactome: R-HSA-1268020;Reactome: R-HSA-2151201;MetaCyc: PWY-7980;Reactome: R-HSA-8949613;Reactome: R-HSA-163210;KEGG: 00195+7.1.2.2 "Oxidative phosphorylation";"Mitochondrial protein import";"Transcriptional activation of mitochondrial biogenesis";"ATP biosynthesis";"Cristae formation";"Formation of ATP by chemiosmotic coupling";"Photosynthesis" XP_037821819.1 3 KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807;Reactome: R-HSA-6798695 "Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation" XP_037813439.1 23 Reactome: R-HSA-428930;Reactome: R-HSA-392170;Reactome: R-HSA-418594;Reactome: R-HSA-418592;Reactome: R-HSA-416482;Reactome: R-HSA-8964616;Reactome: R-HSA-392451;Reactome: R-HSA-418597;Reactome: R-HSA-416476;Reactome: R-HSA-4086398;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-418217;Reactome: R-HSA-381676;Reactome: R-HSA-500657;Reactome: R-HSA-420092;Reactome: R-HSA-9009391;Reactome: R-HSA-400042;Reactome: R-HSA-8964315;Reactome: R-HSA-392851;Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-456926 "Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 12";"G alpha (i) signalling events";"ADP signalling through P2Y purinoceptor 1";"G alpha (12/13) signalling events";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through PI3Kgamma";"G alpha (z) signalling events";"G alpha (q) signalling events";"Ca2+ pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"G beta:gamma signalling through PLC beta";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Presynaptic function of Kainate receptors";"Glucagon-type ligand receptors";"Extra-nuclear estrogen signaling";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through BTK";"Prostacyclin signalling through prostacyclin receptor";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"Thrombin signalling through proteinase activated receptors (PARs)" XP_037820886.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_037813500.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037810398.1 7 Reactome: R-HSA-5685939;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394;Reactome: R-HSA-5696400;Reactome: R-HSA-110362;Reactome: R-HSA-5696395;Reactome: R-HSA-2173795 "HDR through MMEJ (alt-NHEJ)";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER";"Dual Incision in GG-NER";"POLB-Dependent Long Patch Base Excision Repair";"Formation of Incision Complex in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity" XP_037814270.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037819983.1 7 Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76066 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_037807309.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037817806.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037807163.1 2 Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_037816719.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037806249.1 11 Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-5610787 "G alpha (z) signalling events";"Purine metabolism";"Glucagon signaling in metabolic regulation";"PKA activation";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Hedgehog 'off' state" XP_037821537.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037823657.1 1 Reactome: R-HSA-9640463 "Wax biosynthesis" XP_037816023.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-8953750 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional Regulation by E2F6" XP_037809516.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037826191.1 3 MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33 "Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_037814521.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_037824859.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037808424.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_037827131.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037825300.1 3 MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757 "Folate polyglutamylation";"Folate biosynthesis";"Metabolism of folate and pterines" XP_037817985.1 4 MetaCyc: PWY-7382;KEGG: 00785+2.8.1.8;MetaCyc: PWY-6987;Reactome: R-HSA-389661 "Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation" XP_037819283.1 6 Reactome: R-HSA-6803205;Reactome: R-HSA-6803204;Reactome: R-HSA-6803207;Reactome: R-HSA-139915;Reactome: R-HSA-6804759;Reactome: R-HSA-6803211 "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of PUMA and translocation to mitochondria";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Death Receptors and Ligands" XP_037820739.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037808933.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037810103.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037814349.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_037806560.1 4 Reactome: R-HSA-6782861;MetaCyc: PWY-7286;MetaCyc: PWY-6829;MetaCyc: PWY-7285 "Synthesis of wybutosine at G37 of tRNA(Phe)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"Methylwyosine biosynthesis" XP_037813095.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037809588.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_037814456.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037806675.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_037814319.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037816073.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037807874.1 9 MetaCyc: PWY-7385;MetaCyc: PWY-6118;MetaCyc: PWY-5667;MetaCyc: PWY-7902;KEGG: 00564+1.1.1.94;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7411 "1,3-propanediol biosynthesis (engineered)";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis I";"Glucosylglycerol biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)" XP_037813803.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_037811638.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_037824181.1 2 MetaCyc: PWY-5905;Reactome: R-HSA-204626 "Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine" XP_037816446.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037808589.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_037819706.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_037814820.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_037807909.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_037825274.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-8041 "Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis" XP_037815357.1 13 KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2024101 "Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"CS/DS degradation" XP_037825907.1 182 Reactome: R-HSA-9637628;Reactome: R-HSA-5675221;Reactome: R-HSA-6781827;Reactome: R-HSA-5689880;Reactome: R-HSA-2871837;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-8866652;Reactome: R-HSA-9013507;Reactome: R-HSA-168928;Reactome: R-HSA-8875360;Reactome: R-HSA-936440;Reactome: R-HSA-450302;Reactome: R-HSA-156827;Reactome: R-HSA-4641263;Reactome: R-HSA-917729;Reactome: R-HSA-195253;Reactome: R-HSA-5654733;Reactome: R-HSA-450321;Reactome: R-HSA-2173796;Reactome: R-HSA-1799339;Reactome: R-HSA-1358803;Reactome: R-HSA-937042;Reactome: R-HSA-69231;Reactome: R-HSA-382556;Reactome: R-HSA-5656169;Reactome: R-HSA-68949;Reactome: R-HSA-5689901;Reactome: R-HSA-5685942;Reactome: R-HSA-5205685;Reactome: R-HSA-937039;Reactome: R-HSA-8854050;Reactome: R-HSA-5607764;Reactome: R-HSA-9033241;Reactome: R-HSA-8941858;Reactome: R-HSA-69541;Reactome: R-HSA-5689896;Reactome: R-HSA-1253288;Reactome: R-HSA-8876493;Reactome: R-HSA-156902;Reactome: R-HSA-6804756;Reactome: R-HSA-917937;Reactome: R-HSA-975110;Reactome: R-HSA-936964;Reactome: R-HSA-9613829;Reactome: R-HSA-5696394;Reactome: R-HSA-6804757;Reactome: R-HSA-180534;Reactome: R-HSA-5684264;Reactome: R-HSA-180585;Reactome: R-HSA-5654727;Reactome: R-HSA-3769402;Reactome: R-HSA-9646399;Reactome: R-HSA-2894862;Reactome: R-HSA-2559580;Reactome: R-HSA-2559585;Reactome: R-HSA-8849469;Reactome: R-HSA-4608870;Reactome: R-HSA-201681;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-8863795;Reactome: R-HSA-912631;Reactome: R-HSA-5607761;Reactome: R-HSA-1295596;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-110320;Reactome: R-HSA-2173795;Reactome: R-HSA-975956;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-2408557;Reactome: R-HSA-1236382;Reactome: R-HSA-168638;Reactome: R-HSA-69481;Reactome: R-HSA-5689603;Reactome: R-HSA-9615710;Reactome: R-HSA-6781823;Reactome: R-HSA-5655862;Reactome: R-HSA-8939236;Reactome: R-HSA-72649;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-9013973;Reactome: R-HSA-6783310;Reactome: R-HSA-9014325;Reactome: R-HSA-5687128;Reactome: R-HSA-8866654;Reactome: R-HSA-72689;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-5675482;Reactome: R-HSA-975957;Reactome: R-HSA-977225;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-2122948;Reactome: R-HSA-110312;Reactome: R-HSA-6791226;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-2173791;Reactome: R-HSA-205043;Reactome: R-HSA-9636383;Reactome: R-HSA-937072;Reactome: R-HSA-2565942;Reactome: R-HSA-174084;Reactome: R-HSA-2979096;Reactome: R-HSA-211733;Reactome: R-HSA-5696400;Reactome: R-HSA-1169408;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-1169091;Reactome: R-HSA-179409;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-349425;Reactome: R-HSA-5693607;Reactome: R-HSA-6804760;Reactome: R-HSA-2691232;Reactome: R-HSA-5610780;Reactome: R-HSA-162588;Reactome: R-HSA-5357956;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-192823;Reactome: R-HSA-2672351;Reactome: R-HSA-3322077;Reactome: R-HSA-5362768;Reactome: R-HSA-8948747;Reactome: R-HSA-445989;Reactome: R-HSA-5654732;Reactome: R-HSA-975144;Reactome: R-HSA-6782210;Reactome: R-HSA-209543;Reactome: R-HSA-937041;Reactome: R-HSA-5658442;Reactome: R-HSA-5656121;Reactome: R-HSA-174048;Reactome: R-HSA-3134975;Reactome: R-HSA-2644606;Reactome: R-HSA-8939902;Reactome: R-HSA-2173788;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-5676590;Reactome: R-HSA-5357905;Reactome: R-HSA-174113;Reactome: R-HSA-72764;Reactome: R-HSA-182971;Reactome: R-HSA-202424;Reactome: R-HSA-72706;Reactome: R-HSA-5654726;Reactome: R-HSA-3785653;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-174184;Reactome: R-HSA-5696395;Reactome: R-HSA-209560;Reactome: R-HSA-975163;Reactome: R-HSA-5689877;Reactome: R-HSA-5693565;Reactome: R-HSA-5610785;Reactome: R-HSA-174490;Reactome: R-HSA-5358346;Reactome: R-HSA-2122947;Reactome: R-HSA-5632684;Reactome: R-HSA-72702;Reactome: R-HSA-6807004;Reactome: R-HSA-6782135;Reactome: R-HSA-901032;Reactome: R-HSA-168927;Reactome: R-HSA-175474;Reactome: R-HSA-9645460;Reactome: R-HSA-400253;Reactome: R-HSA-4641258;Reactome: R-HSA-532668 "Modulation by Mtb of host immune system";"Negative regulation of MAPK pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Ub-specific processing proteases";"FCERI mediated NF-kB activation";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulators of DDX58/IFIH1 signaling";"activated TAK1 mediates p38 MAPK activation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of FZD by ubiquitination";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Degradation of beta-catenin by the destruction complex";"Negative regulation of FGFR4 signaling";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"SRP-dependent cotranslational protein targeting to membrane";"Downregulation of ERBB2:ERBB3 signaling";"IRAK2 mediated activation of TAK1 complex";"Cyclin D associated events in G1";"ABC-family proteins mediated transport";"Termination of translesion DNA synthesis";"Orc1 removal from chromatin";"Metalloprotease DUBs";"HDR through Homologous Recombination (HRR)";"Pink/Parkin Mediated Mitophagy";"IRAK1 recruits IKK complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CLEC7A (Dectin-1) signaling";"Peroxisomal protein import";"Regulation of RUNX3 expression and activity";"Stabilization of p53";"Ovarian tumor domain proteases";"Downregulation of ERBB4 signaling";"InlA-mediated entry of Listeria monocytogenes into host cells";"Peptide chain elongation";"Regulation of TP53 Activity through Phosphorylation";"Iron uptake and transport";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Chaperone Mediated Autophagy";"DNA Damage Recognition in GG-NER";"Regulation of TP53 Degradation";"Vpu mediated degradation of CD4";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Vif-mediated degradation of APOBEC3G";"Negative regulation of FGFR2 signaling";"Deactivation of the beta-catenin transactivating complex";"Aggrephagy";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Oxidative Stress Induced Senescence";"Oncogene Induced Senescence";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Asymmetric localization of PCP proteins";"TCF dependent signaling in response to WNT";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"Downregulation of ERBB2 signaling";"Regulation of signaling by CBL";"Dectin-1 mediated noncanonical NF-kB signaling";"Spry regulation of FGF signaling";"Neddylation";"Degradation of GLI2 by the proteasome";"Translesion Synthesis by POLH";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Selenocysteine synthesis";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"NOD1/2 Signaling Pathway";"G2/M Checkpoints";"UCH proteinases";"Late endosomal microautophagy";"Formation of TC-NER Pre-Incision Complex";"Translesion synthesis by POLK";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Translation initiation complex formation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"TICAM1-dependent activation of IRF3/IRF7";"Fanconi Anemia Pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"MAPK6/MAPK4 signaling";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of a pool of free 40S subunits";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of necroptotic cell death";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Amyloid fiber formation";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"ER-Phagosome pathway";"Activated NOTCH1 Transmits Signal to the Nucleus";"Translesion synthesis by REV1";"Major pathway of rRNA processing in the nucleolus and cytosol";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"NRIF signals cell death from the nucleus";"Prevention of phagosomal-lysosomal fusion";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Regulation of PLK1 Activity at G2/M Transition";"Autodegradation of Cdh1 by Cdh1:APC/C";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dual Incision in GG-NER";"ISG15 antiviral mechanism";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Activation of NF-kappaB in B cells";"APC-Cdc20 mediated degradation of Nek2A";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Autodegradation of the E3 ubiquitin ligase COP1";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Methylation";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Degradation of GLI1 by the proteasome";"Budding and maturation of HIV virion";"TNFR1-induced NFkappaB signaling pathway";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Viral mRNA Translation";"Stimuli-sensing channels";"Glycogen synthesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN localization";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Negative regulation of FGFR3 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"p75NTR recruits signalling complexes";"IKK complex recruitment mediated by RIP1";"Regulation of RAS by GAPs";"Translesion synthesis by POLI";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of innate immune responses to cytosolic DNA";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of RUNX2 expression and activity";"Downregulation of TGF-beta receptor signaling";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"NIK-->noncanonical NF-kB signaling";"Regulation of TNFR1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Eukaryotic Translation Termination";"EGFR downregulation";"Downstream TCR signaling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Negative regulation of FGFR1 signaling";"Myoclonic epilepsy of Lafora";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Formation of Incision Complex in GG-NER";"NF-kB is activated and signals survival";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Josephin domain DUBs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"GLI3 is processed to GLI3R by the proteasome";"Membrane binding and targetting of GAG proteins";"Hedgehog ligand biogenesis";"NOTCH1 Intracellular Domain Regulates Transcription";"Hedgehog 'on' state";"Ribosomal scanning and start codon recognition";"Negative regulation of MET activity";"Dual incision in TC-NER";"ER Quality Control Compartment (ERQC)";"TICAM1, RIP1-mediated IKK complex recruitment";"Assembly Of The HIV Virion";"Alpha-protein kinase 1 signaling pathway";"Circadian Clock";"Degradation of DVL";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_037807802.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037821659.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_037817796.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-1834949 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA" XP_037813087.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214815 "NoRC negatively regulates rRNA expression";"HDACs deacetylate histones" XP_037827786.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037805436.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" XP_037820457.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_037809515.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037813103.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037807801.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037821928.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037823057.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_037806047.1 2 Reactome: R-HSA-5578998;Reactome: R-HSA-174403 "Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling" XP_037826419.1 14 Reactome: R-HSA-70895;KEGG: 00280+2.6.1.42;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5078;MetaCyc: PWY-5076;MetaCyc: PWY-5103;KEGG: 00770+2.6.1.42;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5101;MetaCyc: PWY-5104;MetaCyc: PWY-5108;MetaCyc: PWY-7767;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5057 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation";"Cysteine and methionine metabolism";"L-isoleucine degradation II";"L-leucine degradation III";"L-isoleucine biosynthesis III";"Pantothenate and CoA biosynthesis";"Glucosinolate biosynthesis";"L-isoleucine biosynthesis II";"L-isoleucine biosynthesis IV";"L-isoleucine biosynthesis V";"L-leucine degradation IV (Stickland reaction)";"Valine, leucine and isoleucine biosynthesis";"L-valine degradation II" XP_037812054.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_037812378.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037814915.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037812991.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037817276.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037816756.1 11 MetaCyc: PWY-5686;MetaCyc: PWY-7790;MetaCyc: PWY-7400;KEGG: 00240+6.3.5.5;KEGG: 00250+6.3.5.5;KEGG: 00250+2.1.3.2;KEGG: 00240+3.5.2.3;Reactome: R-HSA-500753;KEGG: 00240+2.1.3.2;MetaCyc: PWY-5154;MetaCyc: PWY-7791 "UMP biosynthesis I";"UMP biosynthesis II";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"UMP biosynthesis III" XP_037810698.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_037812337.1 1 KEGG: 00970+6.1.1.19 "Aminoacyl-tRNA biosynthesis" XP_037825939.1 9 KEGG: 04151+2.7.11.1;Reactome: R-HSA-446353;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-446343;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Cell-extracellular matrix interactions";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Localization of the PINCH-ILK-PARVIN complex to focal adhesions";"Relaxin signaling pathway" XP_037806323.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037814415.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_037821233.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_037825107.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037813729.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037828107.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557 "SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis" XP_037814104.1 26 Reactome: R-HSA-9013695;Reactome: R-HSA-8866907;Reactome: R-HSA-9018519;Reactome: R-HSA-400253;Reactome: R-HSA-201722;Reactome: R-HSA-3899300;Reactome: R-HSA-210744;Reactome: R-HSA-933541;Reactome: R-HSA-9617629;Reactome: R-HSA-381340;Reactome: R-HSA-8941856;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-3214847;Reactome: R-HSA-3134973;Reactome: R-HSA-3371568;Reactome: R-HSA-1912408;Reactome: R-HSA-5621575;Reactome: R-HSA-1234158;Reactome: R-HSA-9614657;Reactome: R-HSA-9013508;Reactome: R-HSA-918233;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862 "NOTCH4 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"Estrogen-dependent gene expression";"Circadian Clock";"Formation of the beta-catenin:TCF transactivating complex";"SUMOylation of transcription cofactors";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"TRAF6 mediated IRF7 activation";"Regulation of FOXO transcriptional activity by acetylation";"Transcriptional regulation of white adipocyte differentiation";"RUNX3 regulates NOTCH signaling";"PPARA activates gene expression";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HATs acetylate histones";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Attenuation phase";"Pre-NOTCH Transcription and Translation";"CD209 (DC-SIGN) signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"FOXO-mediated transcription of cell death genes";"NOTCH3 Intracellular Domain Regulates Transcription";"TRAF3-dependent IRF activation pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_037821940.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_037827633.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037826341.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-174490 "Budding and maturation of HIV virion";"Late endosomal microautophagy";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins" XP_037817350.1 8 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_037810053.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037820301.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037828838.1 3 Reactome: R-HSA-189451;MetaCyc: PWY-7159;KEGG: 00860+1.3.3.3 "Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism" XP_037817921.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_037807329.1 3 Reactome: R-HSA-383280;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "Nuclear Receptor transcription pathway";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_037825431.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_037812514.1 1 MetaCyc: PWY-6938 "NADH repair" XP_037809099.1 3 Reactome: R-HSA-8963684;Reactome: R-HSA-204174;Reactome: R-HSA-156590 "Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation" XP_037807037.1 18 Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-113418 "Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex" XP_037810309.1 6 KEGG: 00230+4.1.1.21;MetaCyc: PWY-6124;KEGG: 00230+6.3.2.6;MetaCyc: PWY-7234;MetaCyc: PWY-6123;Reactome: R-HSA-73817 "Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis" XP_037815455.1 13 Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6802952;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6802946;KEGG: 04714+2.7.11.1 "Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"mTOR signaling pathway";"Human cytomegalovirus infection";"Signaling by BRAF and RAF fusions";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"PI3K-Akt signaling pathway";"Signaling by moderate kinase activity BRAF mutants";"Thermogenesis" XP_037826665.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_037826590.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_037805887.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_037822915.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037811349.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037806773.1 7 KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway" XP_037810615.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037807845.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037816201.1 10 Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-69473 "HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint" XP_037820300.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037814872.1 8 KEGG: 00521+5.5.1.4;MetaCyc: PWY-6580;MetaCyc: PWY-6664;MetaCyc: PWY-4661;MetaCyc: PWY-2301;Reactome: R-HSA-1855183;MetaCyc: PWY-6372;KEGG: 00562+5.5.1.4 "Streptomycin biosynthesis";"Phosphatidylinositol biosynthesis I (bacteria)";"Di-myo-inositol phosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Myo-inositol biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol phosphate metabolism" XP_037815715.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_037826361.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037813731.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037806753.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" XP_037822770.1 4 Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-375165 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth" XP_037816063.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_037810456.1 6 MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_037824551.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037827081.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956 "L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_037812385.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037814956.1 5 MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-7822 "Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)" XP_037806954.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_037817835.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037812492.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_037814741.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_037826266.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876 "(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs" XP_037810316.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497 "COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Aggrephagy";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_037805446.1 2 Reactome: R-HSA-177128;Reactome: R-HSA-177135 "Conjugation of salicylate with glycine";"Conjugation of benzoate with glycine" XP_037812466.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037819956.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037825911.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_037821315.1 3 Reactome: R-HSA-8936459;Reactome: R-HSA-427413;Reactome: R-HSA-400206 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha" XP_037809413.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_037818016.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037814533.1 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_037826439.1 1 Reactome: R-HSA-2468052 "Establishment of Sister Chromatid Cohesion" XP_037825555.1 5 MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-5083 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation" XP_037824430.1 5 Reactome: R-HSA-186763;Reactome: R-HSA-5218921;Reactome: R-HSA-3928662;Reactome: R-HSA-8849471;Reactome: R-HSA-5658442 "Downstream signal transduction";"VEGFR2 mediated cell proliferation";"EPHB-mediated forward signaling";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Regulation of RAS by GAPs" XP_037815589.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037820324.1 4 Reactome: R-HSA-2408522;Reactome: R-HSA-379716;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.6 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_037807867.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7602 "Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_037811625.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_037809502.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_037812312.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_037815353.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_037806399.1 8 KEGG: 00051+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1;KEGG: 00520+2.7.1.1 "Fructose and mannose metabolism";"Galactose metabolism";"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis / Gluconeogenesis";"Glycolysis";"Streptomycin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_037818831.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_037819324.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037827523.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037813673.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037826332.1 20 MetaCyc: PWY-7606;MetaCyc: PWY-7291;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7854;MetaCyc: PWY-7574;Reactome: R-HSA-9033241;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-7858;MetaCyc: PWY-7340;MetaCyc: PWY-7337;MetaCyc: PWY-735;MetaCyc: PWY-5136;MetaCyc: PWY-6837;MetaCyc: PWY-6920;MetaCyc: PWY-7288;KEGG: 00592+1.3.3.6;KEGG: 00071+1.3.3.6 "Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoyl-coa degradation II";"Peroxisomal protein import";"beta-Alanine metabolism";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(5Z)-dodecenoate biosynthesis II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"alpha-Linolenic acid metabolism";"Fatty acid degradation" XP_037809202.1 11 MetaCyc: PWY-5381;MetaCyc: PWY-6607;KEGG: 00230+3.1.3.5;KEGG: 00240+3.1.3.5;MetaCyc: PWY-6596;MetaCyc: PWY-7185;MetaCyc: PWY-6606;MetaCyc: PWY-7821;KEGG: 00760+3.1.3.5;MetaCyc: PWY-5695;MetaCyc: PWY-6608 "Pyridine nucleotide cycling (plants)";"Guanosine nucleotides degradation I";"Purine metabolism";"Pyrimidine metabolism";"Adenosine nucleotides degradation I";"UTP and CTP dephosphorylation I";"Guanosine nucleotides degradation II";"Tunicamycin biosynthesis";"Nicotinate and nicotinamide metabolism";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation III" XP_037809584.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_037812755.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037824613.1 2 MetaCyc: PWY-7802;MetaCyc: PWY-7799 "N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)" XP_037828550.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037807592.1 9 KEGG: 00480+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-6842;KEGG: 00983+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;MetaCyc: PWY-4061;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7112 "Glutathione metabolism";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification II";"Drug metabolism - other enzymes";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification I";"Metabolism of xenobiotics by cytochrome P450";"4-hydroxy-2-nonenal detoxification" XP_037809562.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037821278.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_037816862.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037819347.1 5 MetaCyc: PWY-6344;Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2 "L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism" XP_037808892.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037807780.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037821013.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037818084.1 1 Reactome: R-HSA-1614558 "Degradation of cysteine and homocysteine" XP_037814912.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037817040.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037808430.1 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" XP_037807784.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_037822544.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_037819092.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037820920.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733 "Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_037814882.1 6 MetaCyc: PWY-7900;MetaCyc: PWY-622;KEGG: 00500+3.2.1.1;KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067;Reactome: R-HSA-189085 "Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate" XP_037818637.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation" XP_037820775.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037821821.1 17 Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-6790901;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-6791226 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Peptide chain elongation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"rRNA modification in the nucleus and cytosol";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037820564.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037816711.1 56 Reactome: R-HSA-69017;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-174154;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-8854050;Reactome: R-HSA-5689603;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-211733 "CDK-mediated phosphorylation and removal of Cdc6";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"APC/C:Cdc20 mediated degradation of Securin";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of AXIN";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"UCH proteinases";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation" XP_037807631.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_037823963.1 17 Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-6790901 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Viral mRNA Translation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"rRNA modification in the nucleus and cytosol" XP_037817910.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_037821772.1 18 MetaCyc: PWY-1622;MetaCyc: PWY-5392;KEGG: 00270+1.1.1.37;KEGG: 00020+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-6728;Reactome: R-HSA-70263;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5690;KEGG: 00620+1.1.1.37;MetaCyc: PWY-561;KEGG: 00720+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-8086;MetaCyc: PWY-7383;MetaCyc: PWY-5913;MetaCyc: PWY-7115 "Formaldehyde assimilation I (serine pathway)";"Reductive TCA cycle II";"Cysteine and methionine metabolism";"Citrate cycle (TCA cycle)";"Carbon fixation in photosynthetic organisms";"Methylaspartate cycle";"Gluconeogenesis";"Glyoxylate and dicarboxylate metabolism";"TCA cycle II (plants and fungi)";"Pyruvate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Methane metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Anaerobic energy metabolism (invertebrates, cytosol)";"Partial TCA cycle (obligate autotrophs)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" XP_037805882.1 5 KEGG: 00190+7.1.1.8;MetaCyc: PWY-3781;MetaCyc: PWY-7279;MetaCyc: PWY-6692;MetaCyc: PWY-7082 "Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Fe(II) oxidation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)" XP_037806125.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_037810656.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037807622.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_037808784.1 2 KEGG: 00230+4.6.1.1;Reactome: R-HSA-196819 "Purine metabolism";"Vitamin B1 (thiamin) metabolism" XP_037811829.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-77588;Reactome: R-HSA-191859;Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-111367 "mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs" XP_037807952.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_037806394.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037825557.1 5 MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism" XP_037810693.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_037828000.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646 "Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification" XP_037811476.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037821127.1 2 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis" XP_037813558.1 7 Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68949 "CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"G1/S-Specific Transcription";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin" XP_037819854.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72764 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Peptide chain elongation";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination" XP_037822408.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037819838.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_037816710.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037826049.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_037809257.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_037811185.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-432722;Reactome: R-HSA-6811440;Reactome: R-HSA-6798695;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis";"Retrograde transport at the Trans-Golgi-Network";"Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis" XP_037810088.1 4 MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14 "Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism" XP_037811736.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037821319.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037815995.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037822681.1 3 KEGG: 00643+1.13.11.5;KEGG: 00350+1.13.11.5;Reactome: R-HSA-8963684 "Styrene degradation";"Tyrosine metabolism";"Tyrosine catabolism" XP_037825038.1 4 Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;MetaCyc: PWY-7119 "Glycosphingolipid metabolism";"Sphingolipid metabolism";"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)" XP_037806630.1 8 Reactome: R-HSA-180024;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-442720;Reactome: R-HSA-983231 "DARPP-32 events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production" XP_037816899.1 5 Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920 "Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability" XP_037816215.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_037810317.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436 "Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic" XP_037807955.1 7 Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-1538133 "Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"G0 and Early G1" XP_037814761.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_037827085.1 6 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" XP_037821894.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_037819494.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-983231 "Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production" XP_037810153.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037806718.1 10 Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-3214847;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-73776 "Transcription of the HIV genome";"HIV Transcription Initiation";"HATs acetylate histones";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape" XP_037822278.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037813865.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_037806681.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_037808929.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037805788.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_037820455.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_037825375.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037823473.1 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_037808943.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037806246.1 5 MetaCyc: PWY-7185;MetaCyc: PWY-7176;MetaCyc: PWY-7177;KEGG: 00240+6.3.4.2;Reactome: R-HSA-499943 "UTP and CTP dephosphorylation I";"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation II";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_037809806.1 7 Reactome: R-HSA-70268;KEGG: 00020+1.2.4.1;KEGG: 00010+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-204174;Reactome: R-HSA-389661;Reactome: R-HSA-5362517 "Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid" XP_037824878.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_037826964.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037805790.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_037823837.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_037828683.1 1 Reactome: R-HSA-446193 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_037805315.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_037817899.1 9 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"tRNA modification in the nucleus and cytosol";"Relaxin signaling pathway" XP_037825597.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037824358.1 4 Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_037817856.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037808176.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037827017.1 5 Reactome: R-HSA-196757;MetaCyc: PWY-3841;MetaCyc: PWY-2201;KEGG: 00720+1.5.1.20;KEGG: 00670+1.5.1.20 "Metabolism of folate and pterines";"Folate transformations II (plants)";"Folate transformations I";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate" XP_037805810.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_037811532.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037814823.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037805562.1 2 Reactome: R-HSA-72764;Reactome: R-HSA-156581 "Eukaryotic Translation Termination";"Methylation" XP_037818946.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_037815963.1 26 Reactome: R-HSA-9648025;Reactome: R-HSA-190840;Reactome: R-HSA-437239;Reactome: R-HSA-389977;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-389960;Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-9619483 "EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recycling pathway of L1";"Post-chaperonin tubulin folding pathway";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"HCMV Early Events";"Gap junction assembly";"RHO GTPases Activate Formins";"Aggrephagy";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"Formation of tubulin folding intermediates by CCT/TriC";"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Activation of AMPK downstream of NMDARs" XP_037826973.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_037814347.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_037818658.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_037819542.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_037828560.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037825362.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037824666.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_037827133.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037806335.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7035;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7601 "Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_037827787.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_037810151.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037816674.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037815268.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037812764.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037822167.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_037825781.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_037823330.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_037806286.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037823612.1 3 Reactome: R-HSA-6798695;MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9 "Neutrophil degranulation";"Glutamate removal from folates";"Folate biosynthesis" XP_037811825.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_037817190.1 42 Reactome: R-HSA-2559582;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-110329;Reactome: R-HSA-2559580;Reactome: R-HSA-2559586;Reactome: R-HSA-8936459;Reactome: R-HSA-3214842;Reactome: R-HSA-2299718;Reactome: R-HSA-171306;Reactome: R-HSA-5334118;Reactome: R-HSA-9610379;Reactome: R-HSA-9616222;Reactome: R-HSA-427359;Reactome: R-HSA-3214847;Reactome: R-HSA-5617472;Reactome: R-HSA-912446;Reactome: R-HSA-977225;Reactome: R-HSA-5578749;Reactome: R-HSA-3214858;Reactome: R-HSA-110330;Reactome: R-HSA-1912408;Reactome: R-HSA-3214841;Reactome: R-HSA-73772;Reactome: R-HSA-9609690;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-110328;Reactome: R-HSA-427413;Reactome: R-HSA-201722;Reactome: R-HSA-8939236;Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-9018519;Reactome: R-HSA-110331;Reactome: R-HSA-1221632;Reactome: R-HSA-606279;Reactome: R-HSA-69473;Reactome: R-HSA-5250924;Reactome: R-HSA-73728;Reactome: R-HSA-5693565;Reactome: R-HSA-5625886 "Senescence-Associated Secretory Phenotype (SASP)";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Cleavage of the damaged pyrimidine";"Oxidative Stress Induced Senescence";"DNA Damage/Telomere Stress Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HDMs demethylate histones";"Condensation of Prophase Chromosomes";"Packaging Of Telomere Ends";"DNA methylation";"HCMV Late Events";"Transcriptional regulation of granulopoiesis";"SIRT1 negatively regulates rRNA expression";"HATs acetylate histones";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Meiotic recombination";"Amyloid fiber formation";"Transcriptional regulation by small RNAs";"RMTs methylate histone arginines";"Recognition and association of DNA glycosylase with site containing an affected purine";"Pre-NOTCH Transcription and Translation";"PKMTs methylate histone lysines";"RNA Polymerase I Promoter Escape";"HCMV Early Events";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"NoRC negatively regulates rRNA expression";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"Estrogen-dependent gene expression";"Cleavage of the damaged purine";"Meiotic synapsis";"Deposition of new CENPA-containing nucleosomes at the centromere";"G2/M DNA damage checkpoint";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Opening";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3" XP_037806871.1 7 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis" XP_037807311.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037817157.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037806340.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs" XP_037819118.1 4 Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis" XP_037825114.1 5 MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-5083 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation" XP_037828259.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037809027.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037808944.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037819276.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_037828288.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_037810718.1 2 KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_037822958.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037826830.1 1 Reactome: R-HSA-419771 "Opsins" XP_037825490.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037817945.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_037820993.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_037819243.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037818640.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-6798695 "SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation" XP_037820254.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037810219.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_037812739.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_037825222.1 2 Reactome: R-HSA-8875656;Reactome: R-HSA-8873719 "MET receptor recycling";"RAB geranylgeranylation" XP_037817266.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037817741.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_037810616.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037807685.1 6 KEGG: 00270+2.6.1.52;MetaCyc: PWY-8010;KEGG: 00680+2.6.1.52;KEGG: 00750+2.6.1.52;KEGG: 00260+2.6.1.52;Reactome: R-HSA-977347 "Cysteine and methionine metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Methane metabolism";"Vitamin B6 metabolism";"Glycine, serine and threonine metabolism";"Serine biosynthesis" XP_037825541.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_037823059.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_037811382.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037807386.1 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_037824335.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037817927.1 20 Reactome: R-HSA-69091;Reactome: R-HSA-5685938;Reactome: R-HSA-110312;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-6782135;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-174411;Reactome: R-HSA-69473;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169 "Polymerase switching";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by REV1";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual incision in TC-NER";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Polymerase switching on the C-strand of the telomere";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis" XP_037809555.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037819039.1 14 KEGG: 00561+2.3.1.51;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-8055;MetaCyc: PWY-7417;MetaCyc: PWY-7587;MetaCyc: PWY-5981;MetaCyc: PWY-7782;MetaCyc: PWY-7589;MetaCyc: PWY-8053;MetaCyc: PWY-7411 "Glycerolipid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)" XP_037812035.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_037816643.1 2 Reactome: R-HSA-5663220;Reactome: R-HSA-376176 "RHO GTPases Activate Formins";"Signaling by ROBO receptors" XP_037810404.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037821696.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_037813962.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_037821578.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037811589.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037826725.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_037827893.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_037819727.1 14 MetaCyc: PWY-8051;Reactome: R-HSA-1483213;KEGG: 00561+3.1.3.4;KEGG: 00564+3.1.3.4;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052;Reactome: R-HSA-75109;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053;Reactome: R-HSA-4419969;Reactome: R-HSA-1483191;MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-6453 "Anandamide biosynthesis I";"Synthesis of PE";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Triglyceride biosynthesis";"Ether lipid metabolism";"Anandamide biosynthesis II";"Depolymerisation of the Nuclear Lamina";"Synthesis of PC";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis" XP_037810838.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037809633.1 22 Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-6811558;Reactome: R-HSA-9648025;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-432142;Reactome: R-HSA-5358751;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-5675221;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-389513;Reactome: R-HSA-5339716 "T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"EML4 and NUDC in mitotic spindle formation";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"RAF activation";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Platelet sensitization by LDL";"S45 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Negative regulation of MAPK pathway";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Misspliced GSK3beta mutants stabilize beta-catenin" XP_037805306.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_037805631.1 4 Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724 "HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription" XP_037826548.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_037809055.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037823971.1 7 Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-1655829;Reactome: R-HSA-168333;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-203927 "Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"NEP/NS2 Interacts with the Cellular Export Machinery";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"MicroRNA (miRNA) biogenesis" XP_037810915.1 4 Reactome: R-HSA-166058;Reactome: R-HSA-975138;Reactome: R-HSA-975871;Reactome: R-HSA-6799198 "MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 cascade initiated on plasma membrane";"Complex I biogenesis" XP_037826794.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957 "Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_037826380.1 14 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2467813;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2565942 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Separation of Sister Chromatids";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Regulation of PLK1 Activity at G2/M Transition" XP_037827115.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_037821977.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination" XP_037822918.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037827967.1 6 KEGG: 00680+5.4.2.11;KEGG: 00260+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-8004;KEGG: 00010+5.4.2.11;MetaCyc: PWY-5484 "Methane metabolism";"Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)" XP_037809531.1 24 Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-9648025;Reactome: R-HSA-190840 "COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"Aggrephagy";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Gap junction assembly";"Cilium Assembly";"HCMV Early Events";"Recycling pathway of L1";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane" XP_037807342.1 2 KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859 "Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade" XP_037827668.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037811911.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037814740.1 4 Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;MetaCyc: PWY-7382 "Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)" XP_037806691.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_037825705.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_037822894.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037822513.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_037810326.1 12 Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436 "Mitotic Prometaphase";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic" XP_037810159.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_037817907.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_037818610.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037826564.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956 "Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Peptide chain elongation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_037821768.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037819984.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_037828453.1 8 KEGG: 00521+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1 "Streptomycin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis";"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Fructose and mannose metabolism" XP_037819621.1 13 KEGG: 00670+6.3.4.3;MetaCyc: PWY-6613;MetaCyc: PWY-2161;MetaCyc: PWY-5497;MetaCyc: PWY-1722;MetaCyc: PWY-2201;MetaCyc: PWY-5030;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;MetaCyc: PWY-3841;Reactome: R-HSA-196757;KEGG: 00720+6.3.4.3 "One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate polyglutamylation";"Purine nucleobases degradation II (anaerobic)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations I";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes" XP_037823672.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_037812399.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037805813.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_037821271.1 14 Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-2022377;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Metabolism of Angiotensinogen to Angiotensins";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination" XP_037816122.1 6 Reactome: R-HSA-8964539;MetaCyc: PWY-6344;MetaCyc: PWY-4981;MetaCyc: PWY-6922;MetaCyc: PWY-3341;KEGG: 00330+2.6.1.13 "Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism" XP_037810003.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-1799339 "Viral mRNA Translation";"Peptide chain elongation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane" XP_037805861.1 13 Reactome: R-HSA-416482;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-3928663;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3928662;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5627117 "G alpha (12/13) signalling events";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Sema4D induced cell migration and growth-cone collapse";"EPHA-mediated growth cone collapse";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"Human cytomegalovirus infection";"EPHB-mediated forward signaling";"Relaxin signaling pathway";"RHO GTPases Activate ROCKs" XP_037809034.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_037808801.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037817121.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037806233.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037814933.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_037811042.1 11 Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-72163;Reactome: R-HSA-2173796 "RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"mRNA Splicing - Major Pathway";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription" XP_037828604.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037817222.1 9 MetaCyc: PWY-8086;Reactome: R-HSA-70263;KEGG: 00720+6.4.1.1;KEGG: 00020+6.4.1.1;Reactome: R-HSA-3371599;KEGG: 00620+6.4.1.1;MetaCyc: PWY-6146;MetaCyc: PWY-6142;Reactome: R-HSA-196780 "(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Defective HLCS causes multiple carboxylase deficiency";"Pyruvate metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Biotin transport and metabolism" XP_037825454.1 4 Reactome: R-HSA-3359463;Reactome: R-HSA-3359462;Reactome: R-HSA-196741;Reactome: R-HSA-8964011 "Defective CUBN causes hereditary megaloblastic anemia 1";"Defective AMN causes hereditary megaloblastic anemia 1";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"HDL clearance" XP_037819702.1 20 KEGG: 00410+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7854;MetaCyc: PWY-7574;Reactome: R-HSA-9033241;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7338;MetaCyc: PWY-5136;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-735;KEGG: 00071+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7288;MetaCyc: PWY-7726;MetaCyc: PWY-7858;MetaCyc: PWY-7340 "beta-Alanine metabolism";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoyl-coa degradation II";"Peroxisomal protein import";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Jasmonic acid biosynthesis";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(5Z)-dodecenoate biosynthesis II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)" XP_037821254.1 7 KEGG: 00562+2.7.8.11;MetaCyc: PWY-7625;KEGG: 00564+2.7.8.11;Reactome: R-HSA-1483226;MetaCyc: PWY-6352;MetaCyc: PWY-6351;KEGG: 04070+2.7.8.11 "Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Glycerophospholipid metabolism";"Synthesis of PI";"3-phosphoinositide biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system" XP_037819744.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037806159.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037807486.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037824498.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_037821133.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_037811905.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037813650.1 10 Reactome: R-HSA-6814122;Reactome: R-HSA-2514853;Reactome: R-HSA-8934903;Reactome: R-HSA-445144;Reactome: R-HSA-201688;Reactome: R-HSA-6804756;Reactome: R-HSA-8939243;Reactome: R-HSA-1483191;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Condensation of Prometaphase Chromosomes";"Receptor Mediated Mitophagy";"Signal transduction by L1";"WNT mediated activation of DVL";"Regulation of TP53 Activity through Phosphorylation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Synthesis of PC";"Neutrophil degranulation";"Regulation of PTEN stability and activity" XP_037813035.1 7 MetaCyc: PWY-7807;MetaCyc: PWY-6605;MetaCyc: PWY-7805;KEGG: 00230+2.4.2.7;Reactome: R-HSA-6798695;MetaCyc: PWY-6610;Reactome: R-HSA-74217 "Glyphosate degradation III";"Adenine and adenosine salvage II";"(aminomethyl)phosphonate degradation";"Purine metabolism";"Neutrophil degranulation";"Adenine salvage";"Purine salvage" XP_037823305.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037808912.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037809003.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_037817043.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037808775.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037820459.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_037817181.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037827761.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_037812479.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_037806357.1 3 MetaCyc: PWY-7800;MetaCyc: PWY-7799;Reactome: R-HSA-2514859 "Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)";"Inactivation, recovery and regulation of the phototransduction cascade" XP_037806420.1 3 Reactome: R-HSA-5628897;Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "TP53 Regulates Metabolic Genes";"Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_037821974.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037821143.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_037815247.1 13 KEGG: 00720+4.2.1.2;MetaCyc: PWY-5690;MetaCyc: PWY-8086;KEGG: 00620+4.2.1.2;MetaCyc: PWY-6728;MetaCyc: PWY-5913;MetaCyc: PWY-7254;KEGG: 00020+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-6969;MetaCyc: PWY-5392;MetaCyc: PWY-561;Reactome: R-HSA-71403 "Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citric acid cycle (TCA cycle)" XP_037811565.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_037805435.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway" XP_037805439.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_037812769.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_037807073.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_037827377.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037828166.1 28 Reactome: R-HSA-6804756;Reactome: R-HSA-5358565;Reactome: R-HSA-68962;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-174437;Reactome: R-HSA-5685938;Reactome: R-HSA-110312;Reactome: R-HSA-5693616;Reactome: R-HSA-3371511;Reactome: R-HSA-5693607;Reactome: R-HSA-6782135;Reactome: R-HSA-69166;Reactome: R-HSA-176187;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-69473;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-3371453;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-110320;Reactome: R-HSA-912446;Reactome: R-HSA-5358606 "Regulation of TP53 Activity through Phosphorylation";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Activation of the pre-replicative complex";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Removal of the Flap Intermediate from the C-strand";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by REV1";"Presynaptic phase of homologous DNA pairing and strand exchange";"HSF1 activation";"Processing of DNA double-strand break ends";"Dual incision in TC-NER";"Removal of the Flap Intermediate";"Activation of ATR in response to replication stress";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Regulation of HSF1-mediated heat shock response";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)" XP_037812390.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037806853.1 7 KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway" XP_037814300.1 6 Reactome: R-HSA-3000171;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-8874081;Reactome: R-HSA-2022090 "Non-integrin membrane-ECM interactions";"Collagen degradation";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures" XP_037808328.1 14 MetaCyc: PWY-8051;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.51;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-7411;MetaCyc: PWY-8053;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-7782;MetaCyc: PWY-7587 "Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)" XP_037828083.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_037817989.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037807280.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037816460.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037825306.1 5 Reactome: R-HSA-430039;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994 "mRNA decay by 5' to 3' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_037826988.1 6 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_037809805.1 7 Reactome: R-HSA-5362517;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-204174;KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1 "Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis" XP_037807363.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037811173.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037806307.1 4 KEGG: 00790+2.8.1.12;Reactome: R-HSA-947581;MetaCyc: PWY-7887;MetaCyc: PWY-6823 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis" XP_037823823.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037827842.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_037809539.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_037818382.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_037806754.1 11 Reactome: R-HSA-2132295;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-6807878;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284 "MHC class II antigen presentation";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"COPI-mediated anterograde transport";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_037820387.1 6 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_037821034.1 6 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-6798695;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Neutrophil degranulation";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport" XP_037816942.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037817354.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037817747.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_037827122.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_037824464.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037814817.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037827536.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_037827106.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_037823898.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-112308 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening" XP_037808597.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_037828293.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037807716.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037814271.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037811533.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037823270.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156827 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_037824760.1 5 Reactome: R-HSA-373080;Reactome: R-HSA-5610787;Reactome: R-HSA-5620922;Reactome: R-HSA-5632684;Reactome: R-HSA-5635838 "Class B/2 (Secretin family receptors)";"Hedgehog 'off' state";"BBSome-mediated cargo-targeting to cilium";"Hedgehog 'on' state";"Activation of SMO" XP_037819302.1 6 Reactome: R-HSA-139915;Reactome: R-HSA-6803211;Reactome: R-HSA-6804759;Reactome: R-HSA-6803205;Reactome: R-HSA-6803204;Reactome: R-HSA-6803207 "Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Death Receptors and Ligands";"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Caspase Activators and Caspases" XP_037806719.1 10 Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-3214847;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167172 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"HATs acetylate histones";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Transcription of the HIV genome" XP_037813512.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_037809495.1 20 Reactome: R-HSA-9033241;MetaCyc: PWY-7854;MetaCyc: PWY-7574;MetaCyc: PWY-7007;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7291;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-6920;MetaCyc: PWY-7288;KEGG: 00592+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7337;MetaCyc: PWY-5136;MetaCyc: PWY-6837;MetaCyc: PWY-7340;MetaCyc: PWY-7858;MetaCyc: PWY-7726 "Peroxisomal protein import";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoyl-coa degradation II";"Methyl ketone biosynthesis (engineered)";"beta-Alanine metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"Jasmonic acid biosynthesis";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)" XP_037828696.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037822695.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037815859.1 5 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-112409;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"RAF-independent MAPK1/3 activation";"T cell receptor signaling pathway";"Negative regulation of MAPK pathway" XP_037817887.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037805627.1 4 Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-8943724 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription" XP_037827484.1 3 MetaCyc: PWY-7999;Reactome: R-HSA-159740;KEGG: 00130+4.1.1.90 "Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_037817212.1 42 Reactome: R-HSA-2559582;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-110329;Reactome: R-HSA-2559586;Reactome: R-HSA-2559580;Reactome: R-HSA-8936459;Reactome: R-HSA-3214842;Reactome: R-HSA-2299718;Reactome: R-HSA-171306;Reactome: R-HSA-5334118;Reactome: R-HSA-9610379;Reactome: R-HSA-9616222;Reactome: R-HSA-427359;Reactome: R-HSA-3214847;Reactome: R-HSA-5617472;Reactome: R-HSA-912446;Reactome: R-HSA-977225;Reactome: R-HSA-5578749;Reactome: R-HSA-3214858;Reactome: R-HSA-110330;Reactome: R-HSA-3214841;Reactome: R-HSA-1912408;Reactome: R-HSA-73772;Reactome: R-HSA-9609690;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-110328;Reactome: R-HSA-427413;Reactome: R-HSA-201722;Reactome: R-HSA-8939236;Reactome: R-HSA-212300;Reactome: R-HSA-4551638;Reactome: R-HSA-9018519;Reactome: R-HSA-110331;Reactome: R-HSA-1221632;Reactome: R-HSA-606279;Reactome: R-HSA-69473;Reactome: R-HSA-5250924;Reactome: R-HSA-73728;Reactome: R-HSA-5693565;Reactome: R-HSA-5625886 "Senescence-Associated Secretory Phenotype (SASP)";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Cleavage of the damaged pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Oxidative Stress Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HDMs demethylate histones";"Condensation of Prophase Chromosomes";"Packaging Of Telomere Ends";"DNA methylation";"HCMV Late Events";"Transcriptional regulation of granulopoiesis";"SIRT1 negatively regulates rRNA expression";"HATs acetylate histones";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Meiotic recombination";"Amyloid fiber formation";"Transcriptional regulation by small RNAs";"RMTs methylate histone arginines";"Recognition and association of DNA glycosylase with site containing an affected purine";"PKMTs methylate histone lysines";"Pre-NOTCH Transcription and Translation";"RNA Polymerase I Promoter Escape";"HCMV Early Events";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"NoRC negatively regulates rRNA expression";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins";"Estrogen-dependent gene expression";"Cleavage of the damaged purine";"Meiotic synapsis";"Deposition of new CENPA-containing nucleosomes at the centromere";"G2/M DNA damage checkpoint";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Opening";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3" XP_037827828.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037812927.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037813806.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_037812965.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis" XP_037808044.1 10 KEGG: 00010+2.7.2.3;MetaCyc: PWY-6901;Reactome: R-HSA-70171;MetaCyc: PWY-8004;Reactome: R-HSA-70263;KEGG: 00710+2.7.2.3;MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-6886;MetaCyc: PWY-5484 "Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycolysis";"Entner-Doudoroff pathway I";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)" XP_037811375.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037812195.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-68952;Reactome: R-HSA-69091 "Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation";"Polymerase switching" XP_037821403.1 5 Reactome: R-HSA-2022090;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-1442490;Reactome: R-HSA-1679131 "Assembly of collagen fibrils and other multimeric structures";"Neutrophil degranulation";"MHC class II antigen presentation";"Collagen degradation";"Trafficking and processing of endosomal TLR" XP_037819544.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_037828168.1 7 Reactome: R-HSA-9018896;Reactome: R-HSA-9018681;Reactome: R-HSA-9020265;Reactome: R-HSA-2142691;Reactome: R-HSA-6798695;Reactome: R-HSA-9018676;Reactome: R-HSA-9023661 "Biosynthesis of E-series 18(S)-resolvins";"Biosynthesis of protectins";"Biosynthesis of aspirin-triggered D-series resolvins";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Neutrophil degranulation";"Biosynthesis of D-series resolvins";"Biosynthesis of E-series 18(R)-resolvins" XP_037811031.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037812771.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037825825.1 4 KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32 "Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism" XP_037816695.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_037807948.1 14 Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-203927;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593 "Ca2+ pathway";"Regulation of PTEN mRNA translation";"MicroRNA (miRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity" XP_037821603.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_037828908.1 3 Reactome: R-HSA-156590;KEGG: 00680+3.1.2.12;MetaCyc: PWY-1801 "Glutathione conjugation";"Methane metabolism";"Formaldehyde oxidation II (glutathione-dependent)" XP_037817745.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_037811847.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-8873719 "Intra-Golgi traffic";"RAB geranylgeranylation" XP_037813961.1 6 Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-76005;Reactome: R-HSA-416993;Reactome: R-HSA-5099900 "Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4" XP_037819613.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_037816044.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037821109.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_037815237.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037819146.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037815772.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037825678.1 4 Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828 "RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis" XP_037814388.1 9 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection" XP_037814913.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037808748.1 10 Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-9018519;Reactome: R-HSA-75953 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Initiation" XP_037825284.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037820095.1 15 Reactome: R-HSA-5693548;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-2559586;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5685939;Reactome: R-HSA-5693568;Reactome: R-HSA-5693565 "Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"HDR through MMEJ (alt-NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_037818824.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037805434.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_037826723.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_037806469.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" XP_037812964.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_037826534.1 3 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion" XP_037821972.1 3 MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" XP_037813295.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_037805309.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037816927.1 5 Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604 "CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling" XP_037805370.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_037808928.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_037819373.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037810522.1 11 KEGG: 00480+1.1.1.42;MetaCyc: PWY-7124;MetaCyc: PWY-5913;MetaCyc: PWY-7268;MetaCyc: PWY-6728;MetaCyc: PWY-6549;KEGG: 00020+1.1.1.42;Reactome: R-HSA-71403;KEGG: 00720+1.1.1.42;MetaCyc: PWY-7254;MetaCyc: PWY-6969 "Glutathione metabolism";"Ethylene biosynthesis V (engineered)";"Partial TCA cycle (obligate autotrophs)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Methylaspartate cycle";"L-glutamine biosynthesis III";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" XP_037806189.1 9 MetaCyc: PWY-5743;MetaCyc: PWY-7115;MetaCyc: PWY-5744;Reactome: R-HSA-1475029;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-241;MetaCyc: PWY-7117;MetaCyc: PWY-6142 "3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"Reversible hydration of carbon dioxide";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_037817678.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216 "Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen chain trimerization" XP_037807355.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_037823681.1 1 KEGG: 00270+2.1.1.37 "Cysteine and methionine metabolism" XP_037813989.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_037813043.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037822739.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037825303.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" XP_037821335.1 10 Reactome: R-HSA-2206292;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23 "MPS VII - Sly syndrome";"HS-GAG degradation";"Galactose metabolism";"Hyaluronan uptake and degradation";"Other glycan degradation";"Sphingolipid metabolism";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series" XP_037825827.1 4 KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803 "alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing" XP_037820297.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037809187.1 1 Reactome: R-HSA-2467813 "Separation of Sister Chromatids" XP_037806679.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_037806326.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7619 "Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis" XP_037806782.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection" XP_037821969.1 15 MetaCyc: PWY-8004;MetaCyc: PWY-2221;MetaCyc: PWY-7383;Reactome: R-HSA-70171;MetaCyc: PWY-6886;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-6142;MetaCyc: PWY-6901;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7218;KEGG: 00230+2.7.1.40;MetaCyc: PWY-5723 "Entner-Doudoroff pathway I";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis";"1-butanol autotrophic biosynthesis (engineered)";"Pyruvate metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Purine metabolism";"Rubisco shunt" XP_037805310.1 7 Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507 "Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus" XP_037821666.1 7 Reactome: R-HSA-6798695;Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389957 "Neutrophil degranulation";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC" XP_037827622.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037828273.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_037828325.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037808753.1 8 Reactome: R-HSA-1989781;MetaCyc: PWY-7391;Reactome: R-HSA-191273;MetaCyc: PWY-922;MetaCyc: PWY-6174;Reactome: R-HSA-2426168;MetaCyc: PWY-7524;KEGG: 00900+1.1.1.34 "PPARA activates gene expression";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway III (archaea)";"Terpenoid backbone biosynthesis" XP_037815314.1 33 Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-9648025;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-68877;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-191859;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-5663220;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-4615885;Reactome: R-HSA-168271 "SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"Separation of Sister Chromatids";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Mitotic Prometaphase";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"snRNP Assembly";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"RHO GTPases Activate Formins";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus" XP_037810695.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_037825424.1 5 Reactome: R-HSA-8873719;Reactome: R-HSA-1660499;Reactome: R-HSA-1445148;Reactome: R-HSA-8876198;Reactome: R-HSA-6798695 "RAB geranylgeranylation";"Synthesis of PIPs at the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RAB GEFs exchange GTP for GDP on RABs";"Neutrophil degranulation" XP_037812949.1 31 Reactome: R-HSA-199220;MetaCyc: PWY-5147;MetaCyc: PWY-7723;MetaCyc: PWY-5367;MetaCyc: PWY-5366;MetaCyc: PWY-8012;MetaCyc: PWY-7664;MetaCyc: PWY-4381;MetaCyc: PWY-5142;MetaCyc: PWY-6519;MetaCyc: PWY-7388;MetaCyc: PWY-5966-1;MetaCyc: PWY-6799;MetaCyc: PWY-5971;MetaCyc: PWYG-321;MetaCyc: PWY-8047;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-75105;MetaCyc: PWY-6282;MetaCyc: PWY-5989;Reactome: R-HSA-2426168;MetaCyc: PWY-7746;Reactome: R-HSA-163765;MetaCyc: PWY-8049;MetaCyc: PWY-5994;MetaCyc: PWY-7663;MetaCyc: PWY-7858;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5973;Reactome: R-HSA-9029558;MetaCyc: PWY-6113 "Vitamin B5 (pantothenate) metabolism";"Oleate biosynthesis I (plants)";"Bacterial bioluminescence";"Petroselinate biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Mupirocin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Acyl-[acyl-carrier protein] thioesterase pathway";"8-amino-7-oxononanoate biosynthesis I";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"";"Bryostatin biosynthesis";"Biotin metabolism";"Fatty acyl-CoA biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Stearate biosynthesis II (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"Mycobacterial sulfolipid biosynthesis";"ChREBP activates metabolic gene expression";"Pederin biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Gondoate biosynthesis (anaerobic)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis";"Cis-vaccenate biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Superpathway of mycolate biosynthesis" XP_037805860.1 13 Reactome: R-HSA-5627117;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3928662;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3928663;Reactome: R-HSA-416572;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-416482 "RHO GTPases Activate ROCKs";"Relaxin signaling pathway";"Human cytomegalovirus infection";"EPHB-mediated forward signaling";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"EPHA-mediated growth cone collapse";"Sema4D induced cell migration and growth-cone collapse";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"G alpha (12/13) signalling events" XP_037807619.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_037820496.1 7 KEGG: 00400+1.14.16.1;Reactome: R-HSA-2160456;KEGG: 00360+1.14.16.1;MetaCyc: PWY-7158;KEGG: 00790+1.14.16.1;MetaCyc: PWY-6134;Reactome: R-HSA-8964208 "Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylketonuria";"Phenylalanine metabolism";"L-phenylalanine degradation V";"Folate biosynthesis";"L-tyrosine biosynthesis IV";"Phenylalanine metabolism" XP_037806119.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_037815974.1 7 Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73980 "Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination" XP_037806997.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_037825231.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_037808957.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037814873.1 6 MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" XP_037826388.1 14 Reactome: R-HSA-380284;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5663220;Reactome: R-HSA-380259;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257 "Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"RHO GTPases Activate Formins";"Loss of Nlp from mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion" XP_037826329.1 20 MetaCyc: PWY-7007;KEGG: 00410+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7574;MetaCyc: PWY-7854;MetaCyc: PWY-7291;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7338;MetaCyc: PWY-5136;MetaCyc: PWY-6837;MetaCyc: PWY-735;MetaCyc: PWY-7337;KEGG: 00071+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7288;MetaCyc: PWY-7858;MetaCyc: PWY-7726;MetaCyc: PWY-7340 "Methyl ketone biosynthesis (engineered)";"beta-Alanine metabolism";"Peroxisomal protein import";"Propanoyl-coa degradation II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Jasmonic acid biosynthesis";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)" XP_037814381.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037816226.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_037827593.1 6 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-6798695 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Neutrophil degranulation" XP_037815370.1 4 KEGG: 00270+1.13.11.20;MetaCyc: PWY-5331;KEGG: 00430+1.13.11.20;Reactome: R-HSA-1614558 "Cysteine and methionine metabolism";"Taurine biosynthesis I";"Taurine and hypotaurine metabolism";"Degradation of cysteine and homocysteine" XP_037822051.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_037812272.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037811719.1 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" XP_037812512.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037818098.1 4 MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912;Reactome: R-HSA-156581 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation" XP_037807620.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_037807846.1 1 MetaCyc: PWY-7379 "Mrna capping II" XP_037811154.1 5 Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-390450 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC" XP_037808217.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_037825068.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037810150.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815 "Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones" XP_037815592.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037815725.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_037808752.1 8 KEGG: 00900+1.1.1.34;Reactome: R-HSA-191273;Reactome: R-HSA-1989781;MetaCyc: PWY-7391;MetaCyc: PWY-7524;MetaCyc: PWY-6174;Reactome: R-HSA-2426168;MetaCyc: PWY-922 "Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"PPARA activates gene expression";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Mevalonate pathway II (archaea)";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I" XP_037822243.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_037805586.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037825380.1 29 Reactome: R-HSA-73772;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-167161;Reactome: R-HSA-75955;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-6781823;Reactome: R-HSA-75953;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-73863;Reactome: R-HSA-6782210;Reactome: R-HSA-167152 "RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"HIV Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Termination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat" XP_037812560.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_037819778.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037817352.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037821667.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_037825983.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037826397.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_037825339.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase" XP_037806336.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7602 "Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_037822672.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_037823787.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_037823432.1 3 KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317 "Galactose metabolism";"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)" XP_037805723.1 4 MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.12;MetaCyc: PWY-7887 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation" XP_037812055.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037826970.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_037819918.1 3 Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.19 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_037814874.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_037807397.1 6 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_037812426.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_037816064.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_037808400.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_037825618.1 3 MetaCyc: PWY-6367;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6368 "D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation" XP_037823744.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_037806975.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_037814262.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037820861.1 12 Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-6804756;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-6796648 "RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes" XP_037813815.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_037805881.1 5 MetaCyc: PWY-7082;MetaCyc: PWY-3781;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7279;MetaCyc: PWY-6692 "Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Fe(II) oxidation" XP_037823377.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_037826629.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037812915.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037811723.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956 "L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Viral mRNA Translation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_037805230.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037819496.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-983231 "Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production" XP_037807052.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037808903.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_037825258.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339 "Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane" XP_037817253.1 3 KEGG: 00860+2.5.1.141;MetaCyc: PWY-7856;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"Heme a biosynthesis";"Heme biosynthesis" XP_037807803.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037809947.1 20 MetaCyc: PWY-7606;MetaCyc: PWY-7291;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7574;MetaCyc: PWY-7854;Reactome: R-HSA-9033241;MetaCyc: PWY-7726;MetaCyc: PWY-7858;MetaCyc: PWY-7340;MetaCyc: PWY-6837;MetaCyc: PWY-5136;MetaCyc: PWY-735;MetaCyc: PWY-7337;KEGG: 00592+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-6920 "Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"beta-Alanine metabolism";"Methyl ketone biosynthesis (engineered)";"Propanoyl-coa degradation II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(5Z)-dodecenoate biosynthesis II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation II (plant peroxisome)";"Jasmonic acid biosynthesis";"10-cis-heptadecenoyl-CoA degradation (yeast)";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"Fatty acid beta-oxidation VII (yeast peroxisome)";"6-gingerol analog biosynthesis (engineered)" XP_037808581.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037812376.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037807864.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037826041.1 4 MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112;MetaCyc: PWY-4361 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_037821073.1 3 Reactome: R-HSA-8875656;Reactome: R-HSA-8854214;Reactome: R-HSA-8856828 "MET receptor recycling";"TBC/RABGAPs";"Clathrin-mediated endocytosis" XP_037826733.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_037823122.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_037821893.1 25 Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-9648025;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-380270;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332 "Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Gap junction assembly";"Cilium Assembly";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"Recruitment of mitotic centrosome proteins and complexes";"RHO GTPases Activate Formins";"Aggrephagy";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin" XP_037806077.1 30 Reactome: R-HSA-167246;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-167152;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-2564830;Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-6781823;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-73772;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-77075 "Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"Cytosolic iron-sulfur cluster assembly";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE" XP_037812086.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037805859.1 13 KEGG: 04151+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416572;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3928663;KEGG: 05163+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-3928662;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5627117;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"G alpha (12/13) signalling events";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Sema4D induced cell migration and growth-cone collapse";"Thermogenesis";"EPHA-mediated growth cone collapse";"Human cytomegalovirus infection";"VEGFA-VEGFR2 Pathway";"EPHB-mediated forward signaling";"mTOR signaling pathway";"RHO GTPases Activate ROCKs";"Relaxin signaling pathway" XP_037813652.1 10 Reactome: R-HSA-6814122;Reactome: R-HSA-2514853;Reactome: R-HSA-8948751;Reactome: R-HSA-201688;Reactome: R-HSA-445144;Reactome: R-HSA-6804756;Reactome: R-HSA-8934903;Reactome: R-HSA-6798695;Reactome: R-HSA-1483191;Reactome: R-HSA-8939243 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Condensation of Prometaphase Chromosomes";"Regulation of PTEN stability and activity";"WNT mediated activation of DVL";"Signal transduction by L1";"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy";"Neutrophil degranulation";"Synthesis of PC";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_037806865.1 7 KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis" XP_037820768.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_037826101.1 5 Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-450341 "FCERI mediated MAPK activation";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors" XP_037824616.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037826311.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037806107.1 8 MetaCyc: PWY-7400;KEGG: 00250+6.3.4.5;Reactome: R-HSA-70635;MetaCyc: PWY-4984;MetaCyc: PWY-4983;MetaCyc: PWY-5154;MetaCyc: PWY-5;KEGG: 00220+6.3.4.5 "L-arginine biosynthesis IV (archaebacteria)";"Alanine, aspartate and glutamate metabolism";"Urea cycle";"Urea cycle";"Nitric oxide biosynthesis II (mammals)";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Canavanine biosynthesis";"Arginine biosynthesis" XP_037813904.1 13 Reactome: R-HSA-4341670;Reactome: R-HSA-4085001;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2206308;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2022857;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00604+3.2.1.23 "Defective NEU1 causes sialidosis";"Sialic acid metabolism";"HS-GAG degradation";"Galactose metabolism";"MPS IV - Morquio syndrome B";"Glycosphingolipid metabolism";"Other glycan degradation";"Keratan sulfate degradation";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Neutrophil degranulation";"Glycosphingolipid biosynthesis - ganglio series" XP_037825397.1 2 KEGG: 00970+6.1.1.2;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_037823653.1 6 Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-399997 "G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion" XP_037822600.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037821068.1 6 Reactome: R-HSA-1483166;MetaCyc: PWY-6118;MetaCyc: PWY-4261;Reactome: R-HSA-163560;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6952 "Synthesis of PA";"Glycerol-3-phosphate shuttle";"Glycerol degradation I";"Triglyceride catabolism";"Glycerophospholipid metabolism";"Glycerophosphodiester degradation" XP_037821967.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037808465.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947 "Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription" XP_037811412.1 5 KEGG: 00240+2.4.2.3;MetaCyc: PWY-5532;Reactome: R-HSA-73621;Reactome: R-HSA-73614;KEGG: 00983+2.4.2.3 "Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine catabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes" XP_037807863.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037828826.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037818819.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" XP_037818360.1 7 MetaCyc: PWY-7841;Reactome: R-HSA-1660662;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7836;MetaCyc: PWY-7838;MetaCyc: PWY-5129;MetaCyc: PWY-7839 "Neolacto-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Ganglio-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Lacto-series glycosphingolipids biosynthesis" XP_037824355.1 4 Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "DARPP-32 events";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_037809554.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-2408557 "Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Viral mRNA Translation";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis" XP_037815449.1 13 Reactome: R-HSA-422356;Reactome: R-HSA-112043;Reactome: R-HSA-139853;Reactome: R-HSA-381676;Reactome: R-HSA-983695;Reactome: R-HSA-2871809;Reactome: R-HSA-5218921;Reactome: R-HSA-1489509;Reactome: R-HSA-4086398;Reactome: R-HSA-114508;Reactome: R-HSA-5607763;Reactome: R-HSA-2029485;Reactome: R-HSA-5578775 "Regulation of insulin secretion";"PLC beta mediated events";"Elevation of cytosolic Ca2+ levels";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FCERI mediated Ca+2 mobilization";"VEGFR2 mediated cell proliferation";"DAG and IP3 signaling";"Ca2+ pathway";"Effects of PIP2 hydrolysis";"CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis";"Ion homeostasis" XP_037815244.1 13 MetaCyc: PWY-5690;KEGG: 00720+4.2.1.2;MetaCyc: PWY-5913;MetaCyc: PWY-6728;KEGG: 00620+4.2.1.2;MetaCyc: PWY-8086;MetaCyc: PWY-6969;MetaCyc: PWY-7254;KEGG: 00020+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-561;Reactome: R-HSA-71403;MetaCyc: PWY-5392 "TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II" XP_037806123.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_037810014.1 3 Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-1268020 "Respiratory electron transport";"Complex I biogenesis";"Mitochondrial protein import" XP_037824949.1 1 KEGG: 00970+6.1.1.1 "Aminoacyl-tRNA biosynthesis" XP_037815401.1 6 Reactome: R-HSA-2426168;MetaCyc: PWY-922;Reactome: R-HSA-191273;Reactome: R-HSA-446199;KEGG: 00900+4.1.1.33;MetaCyc: PWY-7391 "Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Cholesterol biosynthesis";"Synthesis of Dolichyl-phosphate";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)" XP_037823447.1 1 Reactome: R-HSA-428643 "Organic anion transporters" XP_037807060.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_037808197.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037825542.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_037822994.1 11 KEGG: 00770+3.6.1.9;KEGG: 00240+3.6.1.9;KEGG: 00500+3.6.1.9;KEGG: 00230+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7184;MetaCyc: PWY-7821;MetaCyc: PWY-6545;MetaCyc: PWY-7187;MetaCyc: PWY-7206;KEGG: 00760+3.6.1.9 "Pantothenate and CoA biosynthesis";"Pyrimidine metabolism";"Starch and sucrose metabolism";"Purine metabolism";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides dephosphorylation";"Nicotinate and nicotinamide metabolism" XP_037820201.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037819515.1 11 KEGG: 05163+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.1;Reactome: R-HSA-450302;Reactome: R-HSA-2559580;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-171007;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"activated TAK1 mediates p38 MAPK activation";"Oxidative Stress Induced Senescence";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"p38MAPK events";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_037807097.1 4 Reactome: R-HSA-352230;Reactome: R-HSA-71240;Reactome: R-HSA-210991;Reactome: R-HSA-5660862 "Amino acid transport across the plasma membrane";"Tryptophan catabolism";"Basigin interactions";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)" XP_037808729.1 4 Reactome: R-HSA-975144;MetaCyc: PWY-7511;Reactome: R-HSA-937039;Reactome: R-HSA-9020702 "IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Protein ubiquitination";"IRAK1 recruits IKK complex";"Interleukin-1 signaling" XP_037820922.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_037815010.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037806056.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_037818536.1 4 Reactome: R-HSA-611105;Reactome: R-HSA-389661;Reactome: R-HSA-6799198;Reactome: R-HSA-77289 "Respiratory electron transport";"Glyoxylate metabolism and glycine degradation";"Complex I biogenesis";"Mitochondrial Fatty Acid Beta-Oxidation" XP_037826731.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_037828807.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037809568.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037816712.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037816111.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037820253.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037821132.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_037806375.1 4 KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48 "Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Drug metabolism - other enzymes" XP_037823670.1 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_037820094.1 12 Reactome: R-HSA-3214847;Reactome: R-HSA-8941856;Reactome: R-HSA-210744;Reactome: R-HSA-5250924;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-73762;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-9013695 "HATs acetylate histones";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"B-WICH complex positively regulates rRNA expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"RNA Polymerase I Transcription Initiation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"NOTCH4 Intracellular Domain Regulates Transcription" XP_037817201.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_037811033.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037809693.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_037812180.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_037812083.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037818769.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_037808882.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_037809604.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037817272.1 9 Reactome: R-HSA-1855204;MetaCyc: PWY-7039;Reactome: R-HSA-416476;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-112043 "Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events" XP_037805800.1 9 MetaCyc: PWY-7533;MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18;MetaCyc: PWY-4061;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;KEGG: 00983+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7112 "Gliotoxin biosynthesis";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Drug metabolism - other enzymes";"Metabolism of xenobiotics by cytochrome P450";"4-hydroxy-2-nonenal detoxification" XP_037807870.1 9 KEGG: 00564+1.1.1.8;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.94;MetaCyc: PWY-5667;MetaCyc: PWY-7902;MetaCyc: PWY-7385;MetaCyc: PWY-6118 "Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Glucosylglycerol biosynthesis";"1,3-propanediol biosynthesis (engineered)";"Glycerol-3-phosphate shuttle" XP_037815457.1 6 MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;KEGG: 00780+6.3.4.15;MetaCyc: PWY-7382;Reactome: R-HSA-196780;Reactome: R-HSA-3371599 "Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Biotin metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency" XP_037808823.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037817944.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_037817684.1 5 Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-164843;Reactome: R-HSA-6798695 "Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"2-LTR circle formation";"Neutrophil degranulation" XP_037816130.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_037808579.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037816459.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037825135.1 5 MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_037828348.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_037811316.1 8 KEGG: 00710+5.3.1.6;MetaCyc: PWY-1861;Reactome: R-HSA-6791461;KEGG: 00030+5.3.1.6;KEGG: 00051+5.3.1.6;MetaCyc: PWY-5723;Reactome: R-HSA-71336;Reactome: R-HSA-5659996 "Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"RPIA deficiency: failed conversion of RU5P to R5P";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Rubisco shunt";"Pentose phosphate pathway";"RPIA deficiency: failed conversion of R5P to RU5P" XP_037819292.1 1 Reactome: R-HSA-196836 "Vitamin C (ascorbate) metabolism" XP_037819540.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_037812230.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662 "Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling" XP_037820561.1 2 Reactome: R-HSA-1566948;Reactome: R-HSA-2243919 "Elastic fibre formation";"Crosslinking of collagen fibrils" XP_037806925.1 40 MetaCyc: PWY-5109;MetaCyc: PWY-7726;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6944;MetaCyc: PWY-7779;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;MetaCyc: PWY-1361;MetaCyc: PWY-6946;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;MetaCyc: PWY-5138;MetaCyc: PWY-7606;MetaCyc: PWY-7656;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6883;MetaCyc: PWY-7401;MetaCyc: PWY-7216;MetaCyc: PWY-5789;MetaCyc: PWY-7654;MetaCyc: PWY-5177;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;KEGG: 00623+1.1.1.35;MetaCyc: PWY-6583;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;MetaCyc: PWY-7778;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;MetaCyc: PWY-6945;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7007;KEGG: 00903+4.2.1.17;KEGG: 00640+4.2.1.17 "Fermentation to 2-methylbutanoate";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"Androstenedione degradation";"Methyl tert-butyl ether degradation";"Valine, leucine and isoleucine degradation";"Pyruvate fermentation to hexanol (engineered)";"Benzoyl-coa degradation I (aerobic)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Caprolactam degradation";"beta-Alanine metabolism";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Spodoptera littoralis pheromone biosynthesis";"Aminobenzoate degradation";"Pyruvate fermentation to butanol II (engineered)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Glutaryl-coa degradation";"Carbon fixation pathways in prokaryotes";"Benzoate degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Toluene degradation";"Pyruvate fermentation to butanol I";"Lysine degradation";"Tryptophan metabolism";"Fatty acid salvage";"2-methylpropene degradation";"Geraniol degradation";"Fatty acid degradation";"Fatty acid elongation";"Fatty acid beta-oxidation II (plant peroxisome)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Butanoate metabolism";"Phenylalanine metabolism";"Methyl ketone biosynthesis (engineered)";"Limonene and pinene degradation";"Propanoate metabolism" XP_037811743.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037808470.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_037806474.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection" XP_037817309.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_037805497.1 4 Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922;MetaCyc: PWY-5737 "Proline catabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis" XP_037810664.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_037815453.1 9 Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-3928662;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-6794361 "Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Synaptic adhesion-like molecules";"Long-term potentiation";"RAF/MAP kinase cascade";"EPHB-mediated forward signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Neurexins and neuroligins" XP_037825211.1 8 KEGG: 00710+5.3.1.6;MetaCyc: PWY-1861;Reactome: R-HSA-71336;MetaCyc: PWY-5723;Reactome: R-HSA-5659996;Reactome: R-HSA-6791461;KEGG: 00051+5.3.1.6;KEGG: 00030+5.3.1.6 "Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Rubisco shunt";"RPIA deficiency: failed conversion of R5P to RU5P";"RPIA deficiency: failed conversion of RU5P to R5P";"Fructose and mannose metabolism";"Pentose phosphate pathway" XP_037823843.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037823431.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037819433.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-112043 "G alpha (i) signalling events";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"PLC beta mediated events" XP_037815697.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_037808462.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037817004.1 5 Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-72163 "Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway" XP_037816210.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_037822742.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037811877.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_037822697.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037818521.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037823610.1 5 Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2 "Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation" XP_037818728.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037814885.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_037817220.1 9 KEGG: 00720+6.4.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-8086;Reactome: R-HSA-3371599;KEGG: 00620+6.4.1.1;KEGG: 00020+6.4.1.1;MetaCyc: PWY-6146;MetaCyc: PWY-6142;Reactome: R-HSA-196780 "Carbon fixation pathways in prokaryotes";"Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Defective HLCS causes multiple carboxylase deficiency";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Biotin transport and metabolism" XP_037813250.1 3 Reactome: R-HSA-1369062;Reactome: R-HSA-8964058;Reactome: R-HSA-9029569 "ABC transporters in lipid homeostasis";"HDL remodeling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_037822447.1 2 Reactome: R-HSA-444821;Reactome: R-HSA-418555 "Relaxin receptors";"G alpha (s) signalling events" XP_037819024.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_037806338.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7602 "Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_037811023.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037827005.1 4 MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2 "2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation" XP_037809224.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_037817373.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037823218.1 6 Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-456926 "Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)" XP_037822777.1 4 Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-445095 "RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins" XP_037808042.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_037819725.1 14 Reactome: R-HSA-75109;MetaCyc: PWY-8052;KEGG: 00564+3.1.3.4;KEGG: 00561+3.1.3.4;KEGG: 00600+3.1.3.4;Reactome: R-HSA-1483213;MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-6453;MetaCyc: PWY-7782;Reactome: R-HSA-4419969;Reactome: R-HSA-1483191;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053 "Triglyceride biosynthesis";"2-arachidonoylglycerol biosynthesis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Sphingolipid metabolism";"Synthesis of PE";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Depolymerisation of the Nuclear Lamina";"Synthesis of PC";"Ether lipid metabolism";"Anandamide biosynthesis II" XP_037828039.1 5 KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33;Reactome: R-HSA-917937 "Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis";"Iron uptake and transport" XP_037821061.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_037807285.1 2 KEGG: 00860+4.99.1.1;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis" XP_037823516.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_037809959.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037823261.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037827891.1 57 Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5689603;Reactome: R-HSA-8854050;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-6798695;Reactome: R-HSA-4641258;Reactome: R-HSA-8939236;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-4641257;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-69017 "Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"UCH proteinases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"Neutrophil degranulation";"Degradation of DVL";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Degradation of AXIN";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"CDK-mediated phosphorylation and removal of Cdc6" XP_037823815.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037812569.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-6798695 "Glycosphingolipid metabolism";"Neutrophil degranulation" XP_037821359.1 3 KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II" XP_037809438.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_037806155.1 6 KEGG: 00790+4.2.3.12;Reactome: R-HSA-1474151;MetaCyc: PWY-6983;MetaCyc: PWY-5664;MetaCyc: PWY-5663;MetaCyc: PWY-7442 "Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis" XP_037817966.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037828665.1 6 Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450385 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" XP_037817551.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_037819603.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_037819514.1 11 KEGG: 04151+2.7.11.1;Reactome: R-HSA-171007;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-450302 "PI3K-Akt signaling pathway";"p38MAPK events";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Oxidative Stress Induced Senescence";"activated TAK1 mediates p38 MAPK activation" XP_037824157.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037813929.1 9 KEGG: 00980+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00480+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-6842;KEGG: 00983+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-4061;KEGG: 00982+2.5.1.18 "Metabolism of xenobiotics by cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification II";"Drug metabolism - other enzymes";"Glutathione conjugation";"Glutathione-mediated detoxification I";"Drug metabolism - cytochrome P450" XP_037812976.1 6 KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210;Reactome: R-HSA-8949613;MetaCyc: PWY-7980;Reactome: R-HSA-1268020;KEGG: 00190+7.1.2.2 "Photosynthesis";"Formation of ATP by chemiosmotic coupling";"Cristae formation";"ATP biosynthesis";"Mitochondrial protein import";"Oxidative phosphorylation" XP_037813007.1 4 Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange" XP_037827358.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037822853.1 18 MetaCyc: PWY-7221;MetaCyc: PWY-7227;MetaCyc: PWY-7184;MetaCyc: PWY-7198;MetaCyc: PWY-7205;MetaCyc: PWY-7220;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7226;MetaCyc: PWY-7224;MetaCyc: PWY-7222;KEGG: 00983+2.7.4.6;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7197;MetaCyc: PWY-7187;MetaCyc: PWY-7176 "Guanosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis" XP_037818625.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037816163.1 14 MetaCyc: PWY-7587;MetaCyc: PWY-8055;Reactome: R-HSA-9018519;Reactome: R-HSA-8931987;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-8053;Reactome: R-HSA-2426168;KEGG: 00564+2.3.1.15;Reactome: R-HSA-75109;MetaCyc: PWY-5667;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15 "Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Estrogen-dependent gene expression";"RUNX1 regulates estrogen receptor mediated transcription";"Stigma estolide biosynthesis";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Activation of gene expression by SREBF (SREBP)";"Glycerophospholipid metabolism";"Triglyceride biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Glycerolipid metabolism" XP_037823416.1 5 Reactome: R-HSA-879415;Reactome: R-HSA-901042;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-532668 "Advanced glycosylation endproduct receptor signaling";"Calnexin/calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_037817321.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037816851.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037806766.1 7 KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway" XP_037817719.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955 "RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation" XP_037811353.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037813259.1 5 Reactome: R-HSA-380994;Reactome: R-HSA-2426168;Reactome: R-HSA-9614657;Reactome: R-HSA-381183;Reactome: R-HSA-1989781 "ATF4 activates genes in response to endoplasmic reticulum stress";"Activation of gene expression by SREBF (SREBP)";"FOXO-mediated transcription of cell death genes";"ATF6 (ATF6-alpha) activates chaperone genes";"PPARA activates gene expression" XP_037828088.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_037807143.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037821758.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037808980.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037824865.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037819539.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_037806864.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection" XP_037805701.1 56 Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-1169091;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-5689603;Reactome: R-HSA-8854050;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-69017;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974 "GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Activation of NF-kappaB in B cells";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"UCH proteinases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"CDK-mediated phosphorylation and removal of Cdc6";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway" XP_037823900.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-5576893 "Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Phase 2 - plateau phase" XP_037819643.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling" XP_037819541.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_037820971.1 3 Reactome: R-HSA-480985;Reactome: R-HSA-913709;KEGG: 00510+2.4.1.117 "Synthesis of dolichyl-phosphate-glucose";"O-linked glycosylation of mucins";"N-Glycan biosynthesis" XP_037810800.1 3 Reactome: R-HSA-418457;Reactome: R-HSA-392517;Reactome: R-HSA-4086398 "cGMP effects";"Rap1 signalling";"Ca2+ pathway" XP_037827381.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037826065.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037814190.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_037828599.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037827132.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037809629.1 22 Reactome: R-HSA-5358749;Reactome: R-HSA-5675221;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-389513;Reactome: R-HSA-5339716;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-4641262;Reactome: R-HSA-141444;Reactome: R-HSA-5467337;Reactome: R-HSA-2500257;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-432142;Reactome: R-HSA-6811558;Reactome: R-HSA-9648025;Reactome: R-HSA-5467348;Reactome: R-HSA-5358752;Reactome: R-HSA-5673000;Reactome: R-HSA-5467340;Reactome: R-HSA-196299 "S37 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"APC truncation mutants have impaired AXIN binding";"Resolution of Sister Chromatid Cohesion";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"EML4 and NUDC in mitotic spindle formation";"Truncations of AMER1 destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"RAF activation";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade" XP_037813994.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_037815192.1 10 KEGG: 05170+2.7.1.153;KEGG: 00562+2.7.1.153;KEGG: 04070+2.7.1.153;KEGG: 04151+2.7.1.153;KEGG: 05163+2.7.1.153;Reactome: R-HSA-9027276;Reactome: R-HSA-1660499;KEGG: 04150+2.7.1.153;MetaCyc: PWY-6352;KEGG: 05165+2.7.1.153 "Human immunodeficiency virus 1 infection";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Synthesis of PIPs at the plasma membrane";"mTOR signaling pathway";"3-phosphoinositide biosynthesis";"Human papillomavirus infection" XP_037813971.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037824388.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037815552.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_037806074.1 9 MetaCyc: PWY-7852;MetaCyc: PWY-7442;MetaCyc: PWY-5663;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6703;MetaCyc: PWY-5664;MetaCyc: PWY-6983;MetaCyc: PWY-6147;Reactome: R-HSA-1474151 "6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Folate biosynthesis";"Preq0 biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Threo-tetrahydrobiopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_037826028.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037809086.1 4 MetaCyc: PWY-7426;KEGG: 00510+3.2.1.114;MetaCyc: PWY-7920;KEGG: 00513+3.2.1.114 "Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis" XP_037810175.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037818590.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037815181.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037807777.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706 "Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037815720.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_037821161.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037810697.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_037826504.1 3 Reactome: R-HSA-611105;Reactome: R-HSA-1268020;Reactome: R-HSA-6799198 "Respiratory electron transport";"Mitochondrial protein import";"Complex I biogenesis" XP_037813444.1 8 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Activation of RAC1";"Thermogenesis" XP_037811151.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-427413 "HATs acetylate histones";"NoRC negatively regulates rRNA expression" XP_037806140.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_037826084.1 3 Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-5250924 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression" XP_037820498.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037818091.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_037809528.1 4 KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943 "Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_037828896.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_037818392.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism" XP_037808700.1 33 Reactome: R-HSA-5578749;Reactome: R-HSA-5663220;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-141444;Reactome: R-HSA-191859;Reactome: R-HSA-2500257;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-2467813;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-68877;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-9648025;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690 "Transcriptional regulation by small RNAs";"RHO GTPases Activate Formins";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"tRNA processing in the nucleus";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"snRNP Assembly";"Resolution of Sister Chromatid Cohesion";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Separation of Sister Chromatids";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"Mitotic Prometaphase";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"EML4 and NUDC in mitotic spindle formation";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"HCMV Early Events" XP_037824627.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037811682.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_037809934.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-983168 "Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037827140.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_037814304.1 6 KEGG: 04070+2.7.11.13;Reactome: R-HSA-114516;Reactome: R-HSA-416993;Reactome: R-HSA-76005;Reactome: R-HSA-418597;Reactome: R-HSA-5099900 "Phosphatidylinositol signaling system";"Disinhibition of SNARE formation";"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+";"G alpha (z) signalling events";"WNT5A-dependent internalization of FZD4" XP_037814414.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_037805718.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037823239.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037809452.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037812518.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" XP_037808561.1 7 MetaCyc: PWY-7511;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862 "Protein ubiquitination";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_037817744.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_037826458.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037809305.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037828278.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_037815638.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037809234.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_037814386.1 9 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400 "Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"mTOR signaling pathway";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer" XP_037821104.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037814919.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037825965.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_037805244.1 5 KEGG: 00020+4.1.1.32;KEGG: 00010+4.1.1.32;KEGG: 00620+4.1.1.32;Reactome: R-HSA-70263;MetaCyc: PWY-7383 "Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_037824179.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_037813857.1 2 Reactome: R-HSA-5673001;Reactome: R-HSA-8853659 "RAF/MAP kinase cascade";"RET signaling" XP_037816642.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-5663220 "Signaling by ROBO receptors";"RHO GTPases Activate Formins" XP_037808297.1 3 Reactome: R-HSA-1799339;Reactome: R-HSA-1236974;Reactome: R-HSA-9609523 "SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_037811262.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037820634.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037820515.1 3 Reactome: R-HSA-499943;KEGG: 00240+3.5.4.12;MetaCyc: PWY-7210 "Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" XP_037822329.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_037811441.1 11 Reactome: R-HSA-174437;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-69166;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693568 "Removal of the Flap Intermediate from the C-strand";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Removal of the Flap Intermediate";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_037806857.1 7 KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis" XP_037825869.1 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_037812336.1 2 Reactome: R-HSA-166665;Reactome: R-HSA-977606 "Terminal pathway of complement";"Regulation of Complement cascade" XP_037814409.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_037810923.1 5 MetaCyc: PWY-6853;KEGG: 00250+1.2.1.88;Reactome: R-HSA-70688;KEGG: 00330+1.2.1.88;Reactome: R-HSA-389661 "Ethylene biosynthesis II (microbes)";"Alanine, aspartate and glutamate metabolism";"Proline catabolism";"Arginine and proline metabolism";"Glyoxylate metabolism and glycine degradation" XP_037814551.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037807306.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037828707.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037816071.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037820243.1 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" XP_037825064.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport" XP_037807172.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037816763.1 4 Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-72086;MetaCyc: PWY-7375 "RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"Mrna capping I" XP_037812930.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037821502.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037806844.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_037819808.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_037816203.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_037820299.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037805832.1 16 Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-983168 "APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037826113.1 14 MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-8051;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00590+3.1.1.4 "Anandamide biosynthesis II";"Linoleic acid metabolism";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Arachidonic acid metabolism" XP_037825256.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_037810677.1 3 Reactome: R-HSA-5632968;Reactome: R-HSA-5358565;Reactome: R-HSA-5632928 "Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2" XP_037814103.1 26 Reactome: R-HSA-5617472;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-3214847;Reactome: R-HSA-933541;Reactome: R-HSA-9617629;Reactome: R-HSA-381340;Reactome: R-HSA-8941856;Reactome: R-HSA-9614657;Reactome: R-HSA-9013508;Reactome: R-HSA-918233;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-3134973;Reactome: R-HSA-3371568;Reactome: R-HSA-5621575;Reactome: R-HSA-1912408;Reactome: R-HSA-1234158;Reactome: R-HSA-400253;Reactome: R-HSA-3899300;Reactome: R-HSA-201722;Reactome: R-HSA-210744;Reactome: R-HSA-8866907;Reactome: R-HSA-9013695;Reactome: R-HSA-9018519 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RORA activates gene expression";"PPARA activates gene expression";"HATs acetylate histones";"TRAF6 mediated IRF7 activation";"Regulation of FOXO transcriptional activity by acetylation";"Transcriptional regulation of white adipocyte differentiation";"RUNX3 regulates NOTCH signaling";"FOXO-mediated transcription of cell death genes";"NOTCH3 Intracellular Domain Regulates Transcription";"TRAF3-dependent IRF activation pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Attenuation phase";"CD209 (DC-SIGN) signaling";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression by Hypoxia-inducible Factor";"Circadian Clock";"SUMOylation of transcription cofactors";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH4 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression" XP_037820277.1 8 Reactome: R-HSA-5693554;Reactome: R-HSA-8953750;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Transcriptional Regulation by E2F6";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_037816250.1 5 KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;Reactome: R-HSA-446210 "Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine" XP_037811633.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_037809567.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037812625.1 6 Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-6804756 "HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation" XP_037810213.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037821975.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_037823609.1 5 KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661 "Lysine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation" XP_037813612.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_037808023.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_037813892.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_037807901.1 1 Reactome: R-HSA-390696 "Adrenoceptors" XP_037814348.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_037820276.1 7 Reactome: R-HSA-379716;KEGG: 00860+6.1.1.17;Reactome: R-HSA-2408522;Reactome: R-HSA-6782315;MetaCyc: PWY-5188;KEGG: 00970+6.1.1.15;KEGG: 00970+6.1.1.17 "Cytosolic tRNA aminoacylation";"Porphyrin and chlorophyll metabolism";"Selenoamino acid metabolism";"tRNA modification in the nucleus and cytosol";"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis";"Aminoacyl-tRNA biosynthesis" XP_037818118.1 3 Reactome: R-HSA-72165;Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_037805772.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_037821066.1 6 Reactome: R-HSA-163560;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6952;Reactome: R-HSA-1483166;MetaCyc: PWY-6118;MetaCyc: PWY-4261 "Triglyceride catabolism";"Glycerophospholipid metabolism";"Glycerophosphodiester degradation";"Synthesis of PA";"Glycerol-3-phosphate shuttle";"Glycerol degradation I" XP_037818603.1 7 Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-9010553;Reactome: R-HSA-5083628;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629 "Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Regulation of expression of SLITs and ROBOs";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2" XP_037827848.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_037805570.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_037814293.1 6 MetaCyc: PWY-622;Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900 "Starch biosynthesis";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)" XP_037817956.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037813238.1 10 Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-451308;Reactome: R-HSA-442982;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-447038;Reactome: R-HSA-9609736 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Activation of Ca-permeable Kainate Receptor";"Ras activation upon Ca2+ influx through NMDA receptor";"Synaptic adhesion-like molecules";"Long-term potentiation";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"NrCAM interactions";"Assembly and cell surface presentation of NMDA receptors" XP_037812819.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037826282.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037810266.1 5 Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-5675221;Reactome: R-HSA-5673000 "Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of MAPK pathway";"RAF activation" XP_037826836.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_037807068.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_037817236.1 6 Reactome: R-HSA-8862803;Reactome: R-HSA-3299685;MetaCyc: PWY-6854;Reactome: R-HSA-8950505;Reactome: R-HSA-9615017;Reactome: R-HSA-2151201 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Transcriptional activation of mitochondrial biogenesis" XP_037805657.1 5 KEGG: 00760+2.7.7.18;MetaCyc: PWY-7761;Reactome: R-HSA-196807;MetaCyc: PWY-5653;MetaCyc: PWY-5381 "Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)" XP_037809559.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037807000.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_037806346.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7602 "Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_037811909.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037822334.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_037812165.1 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_037826600.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_037814309.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_037827269.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037816233.1 26 Reactome: R-HSA-174437;Reactome: R-HSA-69091;Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-5358565;Reactome: R-HSA-174414;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-69205;Reactome: R-HSA-5696400;Reactome: R-HSA-8866654;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-5358606;Reactome: R-HSA-110320;Reactome: R-HSA-5656121;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-1362277;Reactome: R-HSA-6804114;Reactome: R-HSA-6782210;Reactome: R-HSA-174417;Reactome: R-HSA-4615885;Reactome: R-HSA-5656169 "Removal of the Flap Intermediate from the C-strand";"Polymerase switching";"Translesion synthesis by REV1";"Dual incision in TC-NER";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Processive synthesis on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"G1/S-Specific Transcription";"Dual Incision in GG-NER";"E3 ubiquitin ligases ubiquitinate target proteins";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion Synthesis by POLH";"Translesion synthesis by POLI";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"Transcription of E2F targets under negative control by DREAM complex";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand (Lagging Strand) Synthesis";"SUMOylation of DNA replication proteins";"Termination of translesion DNA synthesis" XP_037821069.1 6 KEGG: 00564+1.1.5.3;MetaCyc: PWY-6952;Reactome: R-HSA-163560;MetaCyc: PWY-6118;MetaCyc: PWY-4261;Reactome: R-HSA-1483166 "Glycerophospholipid metabolism";"Glycerophosphodiester degradation";"Triglyceride catabolism";"Glycerol-3-phosphate shuttle";"Glycerol degradation I";"Synthesis of PA" XP_037828613.1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-6791226 "Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Viral mRNA Translation";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037823155.1 17 Reactome: R-HSA-6798695;MetaCyc: PWY-5695;Reactome: R-HSA-74217;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6627;MetaCyc: PWY-7179-1;MetaCyc: PWY-6611;KEGG: 00240+2.4.2.1;MetaCyc: PWY-7179;MetaCyc: PWY-4202;MetaCyc: PWY-5532;MetaCyc: PWY-6644;MetaCyc: PWY-6608;MetaCyc: PWY-6620;Reactome: R-HSA-74259;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6609 "Neutrophil degranulation";"Inosine 5'-phosphate degradation";"Purine salvage";"Purine metabolism";"Salinosporamide A biosynthesis";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage V";"Pyrimidine metabolism";"Purine deoxyribonucleosides degradation I";"Arsenate detoxification I (mammalian)";"Nucleoside and nucleotide degradation (archaea)";"Fluoroacetate and fluorothreonine biosynthesis";"Guanosine nucleotides degradation III";"Guanine and guanosine salvage";"Purine catabolism";"Nicotinate and nicotinamide metabolism";"Adenine and adenosine salvage III" XP_037823277.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557 "SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis" XP_037828302.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037806350.1 14 MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7036 "Juniperonate biosynthesis";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II" XP_037811261.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037819536.1 17 Reactome: R-HSA-69601;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-75035;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-8953750;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-1433557;KEGG: 05163+2.7.11.1 "Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"G2/M DNA damage checkpoint";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Transcriptional Regulation by E2F6";"mTOR signaling pathway";"Thermogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Signaling by SCF-KIT";"Human cytomegalovirus infection" XP_037828636.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_037807692.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"Clathrin-mediated endocytosis" XP_037825545.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689 "Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" XP_037820280.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037822861.1 8 Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949 "Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin" XP_037826029.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037811184.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-432722;Reactome: R-HSA-6811440;Reactome: R-HSA-8856825;Reactome: R-HSA-6798695 "Clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis";"Retrograde transport at the Trans-Golgi-Network";"Cargo recognition for clathrin-mediated endocytosis";"Neutrophil degranulation" XP_037810639.1 5 Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825 "EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis" XP_037827619.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037808736.1 6 Reactome: R-HSA-6798695;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Neutrophil degranulation";"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_037817720.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events" XP_037814733.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_037827136.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-112308 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening" XP_037820588.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037827934.1 6 Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes" XP_037813795.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533 "Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis" XP_037817888.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037819307.1 3 Reactome: R-HSA-2024096;Reactome: R-HSA-2024101;Reactome: R-HSA-2206296 "HS-GAG degradation";"CS/DS degradation";"MPS II - Hunter syndrome" XP_037813482.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-5689880 "Mitochondrial calcium ion transport";"Ub-specific processing proteases" XP_037828629.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_037820851.1 8 Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-180024;Reactome: R-HSA-5610787 "CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"Hedgehog 'off' state" XP_037814555.1 6 MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" XP_037818976.1 2 Reactome: R-HSA-190873;Reactome: R-HSA-399719 "Gap junction degradation";"Trafficking of AMPA receptors" XP_037827844.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_037826655.1 11 Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-5610787 "G alpha (z) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Hedgehog 'off' state" XP_037805999.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_037819595.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_037823658.1 1 Reactome: R-HSA-9640463 "Wax biosynthesis" XP_037816069.1 11 Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-418594 "Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Hedgehog 'off' state";"G alpha (z) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"PKA activation";"G alpha (i) signalling events" XP_037810321.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Mitotic Prometaphase";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Aggrephagy";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic" XP_037812070.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_037814961.1 2 Reactome: R-HSA-2408508;Reactome: R-HSA-389661 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation" XP_037813237.1 10 Reactome: R-HSA-5673001;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-451308;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-447038;Reactome: R-HSA-399719 "RAF/MAP kinase cascade";"Synaptic adhesion-like molecules";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"NrCAM interactions";"Trafficking of AMPA receptors" XP_037826320.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_037808747.1 9 MetaCyc: PWY-6142;MetaCyc: PWY-7115;Reactome: R-HSA-1475029;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-7117;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reversible hydration of carbon dioxide";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism" XP_037815200.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037809425.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037820093.1 12 Reactome: R-HSA-9013695;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-73762;Reactome: R-HSA-210744;Reactome: R-HSA-350054;Reactome: R-HSA-5250924;Reactome: R-HSA-2644606;Reactome: R-HSA-8941856;Reactome: R-HSA-3214847 "NOTCH4 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RNA Polymerase I Transcription Initiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway";"B-WICH complex positively regulates rRNA expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"HATs acetylate histones" XP_037811432.1 5 MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-7822 "Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)" XP_037814917.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037805422.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037813582.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037815640.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_037818200.1 6 MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23 "Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Sphingolipid metabolism" XP_037809613.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_037805474.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037811882.1 7 Reactome: R-HSA-373080;Reactome: R-HSA-5358346;Reactome: R-HSA-5632681;Reactome: R-HSA-5658034;Reactome: R-HSA-5635838;Reactome: R-HSA-5632684;Reactome: R-HSA-5362798 "Class B/2 (Secretin family receptors)";"Hedgehog ligand biogenesis";"Ligand-receptor interactions";"HHAT G278V abrogates palmitoylation of Hh-Np";"Activation of SMO";"Hedgehog 'on' state";"Release of Hh-Np from the secreting cell" XP_037824768.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_037817564.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_037813017.1 9 Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167162 "RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape" XP_037824683.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037820259.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037824569.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling" XP_037811786.1 10 MetaCyc: PWY-5826;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559 "Hypoglycin biosynthesis";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway" XP_037826714.1 2 MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70 "Pseudouridine degradation";"Pyrimidine metabolism" XP_037825461.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689 "Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits" XP_037817702.1 56 Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-2871837;Reactome: R-HSA-180534;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-5689603;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-68949;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-5610783 "Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"FCERI mediated NF-kB activation";"Vpu mediated degradation of CD4";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"UCH proteinases";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Orc1 removal from chromatin";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI2 by the proteasome" XP_037815307.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037823606.1 5 MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2 "2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation" XP_037821214.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037813484.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-5689880 "Mitochondrial calcium ion transport";"Ub-specific processing proteases" XP_037814909.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037821992.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_037806995.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_037821289.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037814236.1 10 MetaCyc: PWY-7411;MetaCyc: PWY-8053;MetaCyc: PWY-7587;MetaCyc: PWY-8055;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;KEGG: 00564+2.3.1.15 "Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Synthesis of PA";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Glycerophospholipid metabolism" XP_037819391.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_037822494.1 4 Reactome: R-HSA-71737;MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805 "Pyrophosphate hydrolysis";"Glyphosate degradation III";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation" XP_037823404.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_037813370.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_037810584.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037818090.1 5 MetaCyc: PWY-7210;KEGG: 00230+3.6.1.6;MetaCyc: PWY-7185;KEGG: 00240+3.6.1.6;Reactome: R-HSA-6798695 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism";"Neutrophil degranulation" XP_037822748.1 10 Reactome: R-HSA-8941856;Reactome: R-HSA-210744;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-2197563;Reactome: R-HSA-9013695 "RUNX3 regulates NOTCH signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"NOTCH2 intracellular domain regulates transcription";"NOTCH4 Intracellular Domain Regulates Transcription" XP_037812515.1 30 Reactome: R-HSA-917937;Reactome: R-HSA-5610783;Reactome: R-HSA-2565942;Reactome: R-HSA-69231;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-5684264;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-2644606;Reactome: R-HSA-9020702;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-2644607;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-1170546;Reactome: R-HSA-400253;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664 "Iron uptake and transport";"Degradation of GLI2 by the proteasome";"Regulation of PLK1 Activity at G2/M Transition";"Cyclin D associated events in G1";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Interleukin-1 signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Prolactin receptor signaling";"Circadian Clock";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation" XP_037822449.1 2 Reactome: R-HSA-1369007;Reactome: R-HSA-5683371 "Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)" XP_037805880.1 5 MetaCyc: PWY-7082;MetaCyc: PWY-7279;MetaCyc: PWY-3781;KEGG: 00190+7.1.1.8;MetaCyc: PWY-6692 "Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"Fe(II) oxidation" XP_037825669.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_037809532.1 24 Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-9648025;Reactome: R-HSA-190840;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-9619483;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-9609736;Reactome: R-HSA-380320;Reactome: R-HSA-6811436 "RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"HCMV Early Events";"Gap junction assembly";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Activation of AMPK downstream of NMDARs";"Aggrephagy";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic" XP_037819681.1 5 Reactome: R-HSA-376172;Reactome: R-HSA-171007;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.24;Reactome: R-HSA-168638 "DSCAM interactions";"p38MAPK events";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"NOD1/2 Signaling Pathway" XP_037821586.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037812778.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" YP_001425540.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_037819147.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037816284.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_037818855.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_037809193.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_037806428.1 22 Reactome: R-HSA-5358747;Reactome: R-HSA-68877;Reactome: R-HSA-5675221;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-5467337;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-432142;Reactome: R-HSA-5358751;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-9648025;Reactome: R-HSA-6811558;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-5673000 "S33 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Negative regulation of MAPK pathway";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Platelet sensitization by LDL";"S45 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"EML4 and NUDC in mitotic spindle formation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"RAF activation" XP_037821770.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037811332.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037810773.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_037822764.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_037807063.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_037815450.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037814947.1 4 Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-418594;Reactome: R-HSA-201681 "Ub-specific processing proteases";"Degradation of AXIN";"G alpha (i) signalling events";"TCF dependent signaling in response to WNT" XP_037813019.1 9 Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-76042 "RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_037807868.1 9 KEGG: 00564+1.1.1.8;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-7902;MetaCyc: PWY-5667;KEGG: 00564+1.1.1.94;MetaCyc: PWY-6118;MetaCyc: PWY-7385 "Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"1,3-propanediol biosynthesis (engineered)" XP_037814091.1 12 MetaCyc: PWY-1861;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00710+4.1.2.13;KEGG: 00010+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-7385;KEGG: 00051+4.1.2.13;KEGG: 00030+4.1.2.13 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Methane metabolism";"Gluconeogenesis";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Pentose phosphate pathway" XP_037827002.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037823361.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection" XP_037823298.1 18 MetaCyc: PWY-7221;MetaCyc: PWY-7227;MetaCyc: PWY-7220;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7198;MetaCyc: PWY-7205;MetaCyc: PWY-7226;MetaCyc: PWY-7210;MetaCyc: PWY-7224;MetaCyc: PWY-7222;KEGG: 00983+2.7.4.6;MetaCyc: PWY-6545;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-7176 "Guanosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"CMP phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"UTP and CTP de novo biosynthesis" XP_037814295.1 6 KEGG: 04070+2.7.11.13;Reactome: R-HSA-114516;Reactome: R-HSA-416993;Reactome: R-HSA-76005;Reactome: R-HSA-418597;Reactome: R-HSA-5099900 "Phosphatidylinositol signaling system";"Disinhibition of SNARE formation";"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+";"G alpha (z) signalling events";"WNT5A-dependent internalization of FZD4" XP_037824062.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_037814410.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_037820565.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037809706.1 6 KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107 "Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" XP_037810243.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_037827843.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_037817044.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037826856.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-1442490;Reactome: R-HSA-1679131;Reactome: R-HSA-2022090 "Neutrophil degranulation";"MHC class II antigen presentation";"Collagen degradation";"Trafficking and processing of endosomal TLR";"Assembly of collagen fibrils and other multimeric structures" XP_037807548.1 4 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"DARPP-32 events" XP_037823734.1 3 KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I" XP_037806051.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_037820570.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037810125.1 4 Reactome: R-HSA-73621;MetaCyc: PWY-6963;KEGG: 00910+1.4.1.14;KEGG: 00250+1.4.1.14 "Pyrimidine catabolism";"Ammonia assimilation cycle I";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism" XP_037818340.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs" XP_037825970.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037811915.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037814747.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_037810443.1 3 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109 "Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis" XP_037822331.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_037812074.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_037826872.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037813646.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_037812063.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_037817979.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_037828805.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037814610.1 4 Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_037827837.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_037812366.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037806821.1 4 MetaCyc: PWY-7375;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-77075 "Mrna capping I";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE" XP_037805805.1 20 Reactome: R-HSA-110320;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-174411;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-176187;Reactome: R-HSA-6782135;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-110312;Reactome: R-HSA-5685938;Reactome: R-HSA-69091;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-6804756 "Translesion Synthesis by POLH";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching on the C-strand of the telomere";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Activation of ATR in response to replication stress";"Dual incision in TC-NER";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by REV1";"HDR through Single Strand Annealing (SSA)";"Polymerase switching";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of TP53 Activity through Phosphorylation" XP_037812783.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_037808864.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_037809558.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037826026.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037806636.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_037811628.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_037828818.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037812770.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_037816850.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037822330.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_037809715.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037821453.1 5 Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-390471 "Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis" XP_037821494.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037818849.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_037823125.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_037824356.1 4 KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"DARPP-32 events";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037820880.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_037826729.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_037819090.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037807181.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037819504.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_037828582.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_037814350.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_037822613.1 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" XP_037808426.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037820271.1 6 Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107 "Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" XP_037823741.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_037820925.1 16 Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-8986944;Reactome: R-HSA-426496;Reactome: R-HSA-8936459;Reactome: R-HSA-2559580;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-9018519 "MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"Transcriptional Regulation by MECP2";"Post-transcriptional silencing by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Oxidative Stress Induced Senescence";"Ca2+ pathway";"Oncogene Induced Senescence";"Estrogen-dependent gene expression" XP_037824338.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_037807422.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_037808958.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037810520.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467 "Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs" XP_037827179.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_037815296.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_037825426.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_037810323.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690 "COPI-mediated anterograde transport";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events" XP_037819502.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_037817360.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037823899.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_037806789.1 7 Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-1442490;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-177929;Reactome: R-HSA-2122948 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Signaling by EGFR";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_037816515.1 3 Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.5 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_037812730.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_037807853.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037811172.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037815744.1 2 Reactome: R-HSA-5362517;Reactome: R-HSA-204174 "Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_037805378.1 10 MetaCyc: PWY-6554;Reactome: R-HSA-1855191;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6369;MetaCyc: PWY-6362;MetaCyc: PWY-6372;Reactome: R-HSA-1855167;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6361;MetaCyc: PWY-4661 "1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of IPs in the nucleus";"Inositol phosphate metabolism";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)" XP_037812869.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_037813136.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_037818636.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-1834949 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA" XP_037825906.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037824281.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037809968.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037821003.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_037809912.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-6791226 "Association of TriC/CCT with target proteins during biosynthesis";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037808780.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037805691.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037819735.1 4 Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590 "Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"NIK-->noncanonical NF-kB signaling" XP_037808327.1 14 MetaCyc: PWY-7589;MetaCyc: PWY-8053;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-8055;MetaCyc: PWY-7417;MetaCyc: PWY-7587;MetaCyc: PWY-5981;MetaCyc: PWY-7782;MetaCyc: PWY-5667;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51;KEGG: 00564+2.3.1.51 "Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Glycerophospholipid metabolism" XP_037813981.1 4 Reactome: R-HSA-3899300;Reactome: R-HSA-9646399;Reactome: R-HSA-9615710;Reactome: R-HSA-9613829 "SUMOylation of transcription cofactors";"Aggrephagy";"Late endosomal microautophagy";"Chaperone Mediated Autophagy" XP_037813644.1 10 Reactome: R-HSA-201688;Reactome: R-HSA-445144;Reactome: R-HSA-6804756;Reactome: R-HSA-8934903;Reactome: R-HSA-1483191;Reactome: R-HSA-6798695;Reactome: R-HSA-8939243;Reactome: R-HSA-8948751;Reactome: R-HSA-6814122;Reactome: R-HSA-2514853 "WNT mediated activation of DVL";"Signal transduction by L1";"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy";"Synthesis of PC";"Neutrophil degranulation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Condensation of Prometaphase Chromosomes" XP_037823549.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037812988.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037819700.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_037821763.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037818945.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037813085.1 6 Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-429958 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease" XP_037807655.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_037824811.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_037828810.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037808610.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers" XP_037818368.1 2 Reactome: R-HSA-3359473;Reactome: R-HSA-196741 "Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_037816230.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_037817310.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_037810439.1 3 KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I" XP_037805629.1 4 Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724 "RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription" XP_037821372.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_037821338.1 10 KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-2024096;Reactome: R-HSA-2206292;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23 "Other glycan degradation";"Galactose metabolism";"Hyaluronan uptake and degradation";"HS-GAG degradation";"MPS VII - Sly syndrome";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Neutrophil degranulation";"Sphingolipid metabolism" XP_037813285.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_037814145.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_037814124.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037807930.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_037823918.1 26 Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-389977;Reactome: R-HSA-437239;Reactome: R-HSA-9648025;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-389960;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-983189 "Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Gap junction assembly";"HCMV Early Events";"Cilium Assembly";"Post-chaperonin tubulin folding pathway";"Recycling pathway of L1";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Formation of tubulin folding intermediates by CCT/TriC";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Aggrephagy";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins" XP_037809684.1 25 Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-380270;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-9648025;Reactome: R-HSA-437239;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257 "Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"RHO GTPases Activate Formins";"Aggrephagy";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Recycling pathway of L1";"Cilium Assembly";"HCMV Early Events";"Gap junction assembly";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion" XP_037813097.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037814548.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037814447.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_037820098.1 7 MetaCyc: PWY-7586;MetaCyc: PWY-7456;KEGG: 00051+5.4.2.8;MetaCyc: PWY-5659;KEGG: 00520+5.4.2.8;MetaCyc: PWY-882;Reactome: R-HSA-446205 "Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Beta-(1,4)-mannan degradation";"Fructose and mannose metabolism";"GDP-mannose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Synthesis of GDP-mannose" XP_037818697.1 11 Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-418555 "PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"PKA activation";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Purine metabolism";"G alpha (z) signalling events";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events" XP_037815564.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037806418.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037818979.1 2 Reactome: R-HSA-190873;Reactome: R-HSA-399719 "Gap junction degradation";"Trafficking of AMPA receptors" XP_037816692.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_037819619.1 7 Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00310+2.3.1.61;Reactome: R-HSA-71403;KEGG: 00020+2.3.1.61;Reactome: R-HSA-71064;KEGG: 00380+2.3.1.61 "Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Lysine catabolism";"Tryptophan metabolism" XP_037822430.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037817311.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_037805656.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037812628.1 10 Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-3108214;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-69473 "HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"SUMOylation of DNA damage response and repair proteins";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint" XP_037808331.1 2 KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921 "Histidine metabolism";"Histidine catabolism" XP_037810133.1 3 MetaCyc: PWY-8106;MetaCyc: PWY-6700;Reactome: R-HSA-6782315 "Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol" XP_037805530.1 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" XP_037810797.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037812416.1 6 Reactome: R-HSA-2022090;Reactome: R-HSA-8874081;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-3000171 "Assembly of collagen fibrils and other multimeric structures";"MET activates PTK2 signaling";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Collagen degradation";"Non-integrin membrane-ECM interactions" XP_037827522.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037813517.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_037811637.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_037818372.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037823896.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037 "Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions" XP_037807888.1 9 KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-241;MetaCyc: PWY-7117;MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-6142 "Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_037816387.1 32 Reactome: R-HSA-72086;Reactome: R-HSA-72165;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-113418;Reactome: R-HSA-8851708;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-72203;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-6803529;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-72163;Reactome: R-HSA-167172;Reactome: R-HSA-168325;Reactome: R-HSA-77075;Reactome: R-HSA-73779;Reactome: R-HSA-6796648;Reactome: R-HSA-112382 "mRNA Capping";"mRNA Splicing - Minor Pathway";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Formation of the Early Elongation Complex";"Signaling by FGFR2 IIIa TM";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"FGFR2 alternative splicing";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"mRNA Splicing - Major Pathway";"Transcription of the HIV genome";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex" XP_037812326.1 2 Reactome: R-HSA-166665;Reactome: R-HSA-977606 "Terminal pathway of complement";"Regulation of Complement cascade" XP_037808298.1 3 Reactome: R-HSA-9609523;Reactome: R-HSA-1236974;Reactome: R-HSA-1799339 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane" XP_037813726.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037807499.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037806716.1 4 Reactome: R-HSA-917937;KEGG: 00860+1.14.14.18;MetaCyc: PWY-5874;Reactome: R-HSA-189483 "Iron uptake and transport";"Porphyrin and chlorophyll metabolism";"Heme degradation I";"Heme degradation" XP_037816355.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_037813727.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037817241.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037813979.1 22 KEGG: 00030+5.3.1.9;MetaCyc: PWY-7347;MetaCyc: PWY-622;MetaCyc: PWY-7385;MetaCyc: PWY-5384;KEGG: 00500+5.3.1.9;MetaCyc: PWY-5054;MetaCyc: PWY-6992;MetaCyc: PWY-6981;Reactome: R-HSA-6798695;MetaCyc: PWY-621;Reactome: R-HSA-70171;KEGG: 00520+5.3.1.9;KEGG: 00010+5.3.1.9;MetaCyc: PWY-7238;MetaCyc: PWY-6142;MetaCyc: PWY-5659;MetaCyc: PWY-8013;Reactome: R-HSA-5628897;MetaCyc: PWY-3801;MetaCyc: PWY-5514;Reactome: R-HSA-70263 "Pentose phosphate pathway";"Sucrose biosynthesis III";"Starch biosynthesis";"1,3-propanediol biosynthesis (engineered)";"Sucrose degradation IV (sucrose phosphorylase)";"Starch and sucrose metabolism";"D-sorbitol biosynthesis I";"1,5-anhydrofructose degradation";"Chitin biosynthesis";"Neutrophil degranulation";"Sucrose degradation III (sucrose invertase)";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Sucrose biosynthesis II";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"GDP-mannose biosynthesis";"UDP-N-acetyl-D-galactosamine biosynthesis III";"TP53 Regulates Metabolic Genes";"Sucrose degradation II (sucrose synthase)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Gluconeogenesis" XP_037812985.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037805811.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_037812058.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_037825263.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_037807562.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037826617.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957 "Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_037810821.1 27 Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-159236;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-4570464 "snRNP Assembly";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins" XP_037814416.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_037818807.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037812656.1 27 Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-4551638 "Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins" XP_037807259.1 14 Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-6796648 "Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes" XP_037809603.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037808948.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037811945.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037814887.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_037819704.1 1 Reactome: R-HSA-8951664 "Neddylation"