Accession_ID Pathway_Count Pathway_IDs Pathway_Names XP_037301809.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_030020891.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037292489.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037301049.1 13 MetaCyc: PWY-5108;KEGG: 00620+6.2.1.1;MetaCyc: PWY-5132;Reactome: R-HSA-71384;MetaCyc: PWY-7118;MetaCyc: PWY-6672;KEGG: 00680+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00010+6.2.1.1;KEGG: 00630+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-5133 "L-isoleucine biosynthesis V";"Pyruvate metabolism";"Lupulone and humulone biosynthesis";"Ethanol oxidation";"Chitin degradation to ethanol";"Cis-genanyl-coa degradation";"Methane metabolism";"Propanoate metabolism";"Adlupulone and adhumulone biosynthesis";"Glycolysis / Gluconeogenesis";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Colupulone and cohumulone biosynthesis" XP_030022981.1 1 Reactome: R-HSA-5624958 "ARL13B-mediated ciliary trafficking of INPP5E" XP_030023157.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030023866.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "COPII-mediated vesicle transport";"Cargo concentration in the ER" XP_037302319.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_030023439.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72689 "Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits" XP_030037491.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_037293357.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-77595 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs" XP_037295792.1 6 Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex" XP_030025893.2 5 Reactome: R-HSA-75105;Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;Reactome: R-HSA-163765 "Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression" XP_030024721.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_030040203.2 8 Reactome: R-HSA-380320;Reactome: R-HSA-6804115;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912 "Recruitment of NuMA to mitotic centrosomes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane" XP_037300184.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_030025542.2 4 Reactome: R-HSA-156581;MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912 "Methylation";"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis" XP_037296310.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030034964.2 1 Reactome: R-HSA-5250924 "B-WICH complex positively regulates rRNA expression" XP_030023705.2 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_037292419.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_030037700.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878 "MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_030019738.1 2 MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24 "Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis" XP_030039200.2 4 Reactome: R-HSA-3359462;Reactome: R-HSA-196741;Reactome: R-HSA-8964011;Reactome: R-HSA-3359463 "Defective AMN causes hereditary megaloblastic anemia 1";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"HDL clearance";"Defective CUBN causes hereditary megaloblastic anemia 1" XP_030028511.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_030026797.2 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_030032566.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_037295794.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037292488.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_030032346.2 4 Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379726 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_030030203.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_030026127.2 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037299554.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_030034450.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_037294226.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_030024785.2 5 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_037297475.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_030033618.1 3 Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596 "Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I" XP_037301477.1 2 KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201 "Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_037293690.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_030030317.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_037294031.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_030025482.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037294532.1 1 MetaCyc: PWY-7379 "Mrna capping II" XP_030037629.1 16 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-167238;Reactome: R-HSA-8951664;Reactome: R-HSA-75955;Reactome: R-HSA-983168;Reactome: R-HSA-6796648;Reactome: R-HSA-9010553;Reactome: R-HSA-167152 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Pausing and recovery of Tat-mediated HIV elongation";"Neddylation";"RNA Polymerase II Transcription Elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of expression of SLITs and ROBOs";"Formation of HIV elongation complex in the absence of HIV Tat" XP_037297931.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_030040683.1 1 Reactome: R-HSA-5635838 "Activation of SMO" XP_030040872.1 3 MetaCyc: PWY-7999;KEGG: 00130+1.17.4.4;Reactome: R-HSA-6806664 "Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Metabolism of vitamin K" XP_030021027.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_030037192.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557 "Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis" XP_030038231.2 11 Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-1251985;Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-2979096;Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-3928665;Reactome: R-HSA-9013700 "Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"NOTCH4 Activation and Transmission of Signal to the Nucleus" XP_037298027.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037298596.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_030034829.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_037292316.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_037293549.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_030020480.2 6 Reactome: R-HSA-6798695;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;Reactome: R-HSA-9033241;KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6 "Neutrophil degranulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Peroxisomal protein import";"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism" XP_030028581.2 1 Reactome: R-HSA-419771 "Opsins" XP_030028220.2 13 KEGG: 00620+4.2.1.2;MetaCyc: PWY-7254;MetaCyc: PWY-6969;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-7384;MetaCyc: PWY-561;MetaCyc: PWY-8086;MetaCyc: PWY-5392;KEGG: 00020+4.2.1.2;KEGG: 00720+4.2.1.2;MetaCyc: PWY-6728;Reactome: R-HSA-71403 "Pyruvate metabolism";"TCA cycle VII (acetate-producers)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Superpathway of glyoxylate cycle and fatty acid degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)" XP_030038451.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037294052.1 52 Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176 "Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha" XP_030026802.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037293626.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037292921.1 5 Reactome: R-HSA-3134975;Reactome: R-HSA-3249367;Reactome: R-HSA-6798695;Reactome: R-HSA-1834941;Reactome: R-HSA-3270619 "Regulation of innate immune responses to cytosolic DNA";"STAT6-mediated induction of chemokines";"Neutrophil degranulation";"STING mediated induction of host immune responses";"IRF3-mediated induction of type I IFN" XP_030033941.1 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_030020070.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004 "Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity" XP_030040823.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_030041263.1 3 Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I" XP_037292593.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_030029028.1 13 Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-8876725;Reactome: R-HSA-8866654;Reactome: R-HSA-532668;Reactome: R-HSA-3371511;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-110320;Reactome: R-HSA-9646399;Reactome: R-HSA-382556;Reactome: R-HSA-5689877;Reactome: R-HSA-5689896 "Neutrophil degranulation";"Hedgehog ligand biogenesis";"Protein methylation";"E3 ubiquitin ligases ubiquitinate target proteins";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"HSF1 activation";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Translesion Synthesis by POLH";"Aggrephagy";"ABC-family proteins mediated transport";"Josephin domain DUBs";"Ovarian tumor domain proteases" XP_030040668.2 3 KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942;Reactome: R-HSA-174403 "Glutathione metabolism";"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling" XP_037297670.1 16 Reactome: R-HSA-174048;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-176408 "APC/C:Cdc20 mediated degradation of Cyclin B";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase" XP_030029110.1 5 Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855 "Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)" XP_037293301.1 14 MetaCyc: PWY-7782;Reactome: R-HSA-1483166;MetaCyc: PWY-7589;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-5981;MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-7587 "Plasmalogen biosynthesis";"Synthesis of PA";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)" XP_030040606.2 9 Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-674695 "Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events" XP_030036162.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_030031377.2 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037295009.1 13 KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822 "Other glycan degradation";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)" XP_030040582.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_030032996.1 3 Reactome: R-HSA-189451;MetaCyc: PWY-7856;KEGG: 00860+2.5.1.141 "Heme biosynthesis";"Heme a biosynthesis";"Porphyrin and chlorophyll metabolism" XP_030019946.2 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037293554.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037299657.1 13 KEGG: 00630+6.2.1.1;MetaCyc: PWY-5133;KEGG: 00720+6.2.1.1;KEGG: 00010+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00680+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-6672;MetaCyc: PWY-7118;Reactome: R-HSA-71384;KEGG: 00620+6.2.1.1;MetaCyc: PWY-5108;MetaCyc: PWY-5132 "Glyoxylate and dicarboxylate metabolism";"Colupulone and cohumulone biosynthesis";"Carbon fixation pathways in prokaryotes";"Glycolysis / Gluconeogenesis";"Adlupulone and adhumulone biosynthesis";"Methane metabolism";"Propanoate metabolism";"Cis-genanyl-coa degradation";"Chitin degradation to ethanol";"Ethanol oxidation";"Pyruvate metabolism";"L-isoleucine biosynthesis V";"Lupulone and humulone biosynthesis" XP_037298121.1 2 Reactome: R-HSA-6811436;Reactome: R-HSA-8876198 "COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_030023495.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_030032119.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6794361;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958 "Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)" XP_030034768.2 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_030035696.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_030040535.2 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_030024705.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_030028755.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_037297093.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_030032402.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-191859;Reactome: R-HSA-111367 "mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"snRNP Assembly";"SLBP independent Processing of Histone Pre-mRNAs" XP_030022613.2 4 Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-5579026 "Pregnenolone biosynthesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)" XP_037295586.1 10 KEGG: 05170+2.7.1.153;KEGG: 00562+2.7.1.153;KEGG: 04151+2.7.1.153;KEGG: 05165+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 05163+2.7.1.153;KEGG: 04070+2.7.1.153;MetaCyc: PWY-6352;KEGG: 04150+2.7.1.153;Reactome: R-HSA-9027276 "Human immunodeficiency virus 1 infection";"Inositol phosphate metabolism";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Synthesis of PIPs at the plasma membrane";"Human cytomegalovirus infection";"Phosphatidylinositol signaling system";"3-phosphoinositide biosynthesis";"mTOR signaling pathway";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)" XP_030026243.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_030024849.1 24 Reactome: R-HSA-392451;Reactome: R-HSA-418555;Reactome: R-HSA-9009391;Reactome: R-HSA-8964315;Reactome: R-HSA-418592;Reactome: R-HSA-163359;Reactome: R-HSA-392851;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-416482;Reactome: R-HSA-392170;Reactome: R-HSA-418217;Reactome: R-HSA-456926;Reactome: R-HSA-8964616;Reactome: R-HSA-381676;Reactome: R-HSA-4086398;Reactome: R-HSA-400042;Reactome: R-HSA-500657;Reactome: R-HSA-420092;Reactome: R-HSA-418597;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-202040;Reactome: R-HSA-432040 "G beta:gamma signalling through PI3Kgamma";"G alpha (s) signalling events";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through BTK";"ADP signalling through P2Y purinoceptor 1";"Glucagon signaling in metabolic regulation";"Prostacyclin signalling through prostacyclin receptor";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"G alpha (12/13) signalling events";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PLC beta";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through CDC42";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway";"Adrenaline,noradrenaline inhibits insulin secretion";"Presynaptic function of Kainate receptors";"Glucagon-type ligand receptors";"G alpha (z) signalling events";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"G-protein activation";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_030025921.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_030022690.2 8 Reactome: R-HSA-1855183;MetaCyc: PWY-4661;MetaCyc: PWY-6580;MetaCyc: PWY-2301;KEGG: 00521+5.5.1.4;MetaCyc: PWY-6664;MetaCyc: PWY-6372;KEGG: 00562+5.5.1.4 "Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol biosynthesis I (bacteria)";"Myo-inositol biosynthesis";"Streptomycin biosynthesis";"Di-myo-inositol phosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol phosphate metabolism" XP_030031306.1 26 Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-389960;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-389977;Reactome: R-HSA-380320;Reactome: R-HSA-8852276 "Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"HCMV Early Events";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Recycling pathway of L1";"Formation of tubulin folding intermediates by CCT/TriC";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Post-chaperonin tubulin folding pathway";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint" XP_037300765.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_037301758.1 10 Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-2197563 "Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 intracellular domain regulates transcription" XP_037294623.1 9 Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-400253;Reactome: R-HSA-191859;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108 "PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Circadian Clock";"snRNP Assembly";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_037298666.1 6 Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-72163 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway" XP_037294105.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_030040915.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030029451.2 3 MetaCyc: PWY-8106;MetaCyc: PWY-6700;Reactome: R-HSA-6782315 "Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol" XP_030036613.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553 "Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs" XP_037298703.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_030025878.2 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_037302228.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_037294748.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037299981.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_030019688.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030036814.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_030033170.1 3 Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689 "tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I" XP_030030938.2 4 MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17;Reactome: R-HSA-379726 "Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_037294108.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_030035921.1 10 Reactome: R-HSA-445144;Reactome: R-HSA-8939243;Reactome: R-HSA-6804756;Reactome: R-HSA-6814122;Reactome: R-HSA-8948751;Reactome: R-HSA-8934903;Reactome: R-HSA-201688;Reactome: R-HSA-1483191;Reactome: R-HSA-6798695;Reactome: R-HSA-2514853 "Signal transduction by L1";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of TP53 Activity through Phosphorylation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of PTEN stability and activity";"Receptor Mediated Mitophagy";"WNT mediated activation of DVL";"Synthesis of PC";"Neutrophil degranulation";"Condensation of Prometaphase Chromosomes" XP_030031433.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_037299885.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-427389 "HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_037303408.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_030021447.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_030024560.2 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_037295434.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" XP_030041093.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_030020352.2 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_030024557.2 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_037301079.1 83 Reactome: R-HSA-9607240;Reactome: R-HSA-8853338;Reactome: R-HSA-167044;Reactome: R-HSA-186763;Reactome: R-HSA-9664565;Reactome: R-HSA-983695;Reactome: R-HSA-109704;Reactome: R-HSA-1250347;Reactome: R-HSA-1839117;Reactome: R-HSA-180336;Reactome: R-HSA-2219530;Reactome: R-HSA-2871809;Reactome: R-HSA-2424491;Reactome: R-HSA-6807004;Reactome: R-HSA-5654693;Reactome: R-HSA-9028335;Reactome: R-HSA-5654727;Reactome: R-HSA-1433557;Reactome: R-HSA-5654733;Reactome: R-HSA-2871796;Reactome: R-HSA-5654719;Reactome: R-HSA-5654706;Reactome: R-HSA-5654689;Reactome: R-HSA-8851805;Reactome: R-HSA-5663213;Reactome: R-HSA-5654712;Reactome: R-HSA-512988;Reactome: R-HSA-5655302;Reactome: R-HSA-180292;Reactome: R-HSA-9634285;Reactome: R-HSA-8983432;Reactome: R-HSA-1295596;Reactome: R-HSA-912631;Reactome: R-HSA-5673001;Reactome: R-HSA-8856828;Reactome: R-HSA-5654710;Reactome: R-HSA-1250196;Reactome: R-HSA-210993;Reactome: R-HSA-9026519;Reactome: R-HSA-912526;Reactome: R-HSA-8856825;Reactome: R-HSA-112412;Reactome: R-HSA-1433559;Reactome: R-HSA-8853334;Reactome: R-HSA-9028731;Reactome: R-HSA-5654704;Reactome: R-HSA-1236382;Reactome: R-HSA-9034864;Reactome: R-HSA-2029482;Reactome: R-HSA-8853659;Reactome: R-HSA-5654688;Reactome: R-HSA-8851907;Reactome: R-HSA-5655291;Reactome: R-HSA-5654700;Reactome: R-HSA-5654726;Reactome: R-HSA-2428933;Reactome: R-HSA-1963642;Reactome: R-HSA-5637810;Reactome: R-HSA-354194;Reactome: R-HSA-1257604;Reactome: R-HSA-1963640;Reactome: R-HSA-389359;Reactome: R-HSA-5654720;Reactome: R-HSA-375165;Reactome: R-HSA-2179392;Reactome: R-HSA-8875360;Reactome: R-HSA-2730905;Reactome: R-HSA-182971;Reactome: R-HSA-5655253;Reactome: R-HSA-5654699;Reactome: R-HSA-6811558;Reactome: R-HSA-9645135;Reactome: R-HSA-5654732;Reactome: R-HSA-9027284;Reactome: R-HSA-8875656;Reactome: R-HSA-74749;Reactome: R-HSA-8865999;Reactome: R-HSA-8875555;Reactome: R-HSA-5654695;Reactome: R-HSA-74751;Reactome: R-HSA-391160;Reactome: R-HSA-388841;Reactome: R-HSA-179812 "FLT3 Signaling";"Signaling by FGFR3 point mutants in cancer";"Signalling to RAS";"Downstream signal transduction";"Signaling by ERBB2 KD Mutants";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PI3K Cascade";"SHC1 events in ERBB4 signaling";"Signaling by cytosolic FGFR1 fusion mutants";"SHC1 events in EGFR signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"FCERI mediated Ca+2 mobilization";"DAP12 signaling";"Negative regulation of MET activity";"FRS-mediated FGFR1 signaling";"Activated NTRK2 signals through PI3K";"Negative regulation of FGFR2 signaling";"Signaling by SCF-KIT";"Negative regulation of FGFR4 signaling";"FCERI mediated MAPK activation";"SHC-mediated cascade:FGFR4";"FRS-mediated FGFR3 signaling";"PI-3K cascade:FGFR1";"MET activates RAS signaling";"RHO GTPases Activate WASPs and WAVEs";"FRS-mediated FGFR4 signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Signaling by FGFR1 in disease";"GAB1 signalosome";"Constitutive Signaling by Overexpressed ERBB2";"Interleukin-15 signaling";"Spry regulation of FGF signaling";"Regulation of signaling by CBL";"RAF/MAP kinase cascade";"Clathrin-mediated endocytosis";"PI-3K cascade:FGFR3";"SHC1 events in ERBB2 signaling";"Tie2 Signaling";"Activated NTRK2 signals through RAS";"Interleukin receptor SHC signaling";"Cargo recognition for clathrin-mediated endocytosis";"SOS-mediated signalling";"Regulation of KIT signaling";"Signaling by FGFR3 fusions in cancer";"Activated NTRK2 signals through FRS2 and FRS3";"SHC-mediated cascade:FGFR3";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Activated NTRK3 signals through RAS";"Regulation of actin dynamics for phagocytic cup formation";"RET signaling";"SHC-mediated cascade:FGFR1";"MET activates PI3K/AKT signaling";"Signaling by FGFR4 in disease";"FRS-mediated FGFR2 signaling";"Negative regulation of FGFR1 signaling";"SHC-related events triggered by IGF1R";"PI3K events in ERBB2 signaling";"Constitutive Signaling by EGFRvIII";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"PIP3 activates AKT signaling";"GRB2 events in ERBB2 signaling";"CD28 dependent Vav1 pathway";"PI-3K cascade:FGFR4";"NCAM signaling for neurite out-growth";"EGFR Transactivation by Gastrin";"InlB-mediated entry of Listeria monocytogenes into host cell";"Role of LAT2/NTAL/LAB on calcium mobilization";"EGFR downregulation";"Signaling by FGFR2 in disease";"SHC-mediated cascade:FGFR2";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"STAT5 Activation";"Negative regulation of FGFR3 signaling";"Erythropoietin activates RAS";"MET receptor recycling";"Signal attenuation";"MET activates PTPN11";"MET activates RAP1 and RAC1";"PI-3K cascade:FGFR2";"Insulin receptor signalling cascade";"Signal regulatory protein family interactions";"Costimulation by the CD28 family";"GRB2 events in EGFR signaling" XP_037297216.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_030022410.2 5 Reactome: R-HSA-209560;Reactome: R-HSA-209543;Reactome: R-HSA-5205685;Reactome: R-HSA-205043;Reactome: R-HSA-9020702 "NF-kB is activated and signals survival";"p75NTR recruits signalling complexes";"Pink/Parkin Mediated Mitophagy";"NRIF signals cell death from the nucleus";"Interleukin-1 signaling" XP_037297449.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" XP_037294196.1 6 Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68949 "Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin" XP_030027447.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_030033393.1 3 KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161;Reactome: R-HSA-196757 "Folate biosynthesis";"Folate polyglutamylation";"Metabolism of folate and pterines" XP_037300289.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037303200.1 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" XP_037299753.1 7 KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis" XP_030040885.1 1 Reactome: R-HSA-68962 "Activation of the pre-replicative complex" XP_030035044.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9010553 "Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs" XP_030021915.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_030030894.1 33 MetaCyc: PWY-1801;MetaCyc: PWY-6342;MetaCyc: PWY-6587;KEGG: 00982+1.1.1.1;KEGG: 00071+1.1.1.1;MetaCyc: PWY-5057;MetaCyc: PWY-7798;MetaCyc: PWY-6802;MetaCyc: PWY-5079;MetaCyc: PWY-7396;MetaCyc: PWY-6313;MetaCyc: PWY-7118;Reactome: R-HSA-71384;KEGG: 00625+1.1.1.1;MetaCyc: PWY-5076;MetaCyc: PWY-7111;MetaCyc: PWY-3162;KEGG: 00260+1.1.1.1;MetaCyc: PWY-7013;MetaCyc: PWY-5751;MetaCyc: PWY-5486;KEGG: 00626+1.1.1.1;MetaCyc: PWY-6333;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5078;KEGG: 00680+1.1.1.284;MetaCyc: PWY-6871;KEGG: 00830+1.1.1.1;MetaCyc: PWY-5082;KEGG: 00592+1.1.1.1;KEGG: 00980+1.1.1.1;KEGG: 00010+1.1.1.1;MetaCyc: PWY-5480 "Formaldehyde oxidation II (glutathione-dependent)";"Noradrenaline and adrenaline degradation";"Pyruvate fermentation to ethanol III";"Drug metabolism - cytochrome P450";"Fatty acid degradation";"L-valine degradation II";"Protein S-nitrosylation and denitrosylation";"Salidroside biosynthesis";"L-phenylalanine degradation III";"Butanol and isobutanol biosynthesis (engineered)";"Serotonin degradation";"Chitin degradation to ethanol";"Ethanol oxidation";"Chloroalkane and chloroalkene degradation";"L-leucine degradation III";"Pyruvate fermentation to isobutanol (engineered)";"L-tryptophan degradation V (side chain pathway)";"Glycine, serine and threonine metabolism";"(S)-propane-1,2-diol degradation";"Phenylethanol biosynthesis";"Pyruvate fermentation to ethanol II";"Naphthalene degradation";"Acetaldehyde biosynthesis I";"Tyrosine metabolism";"L-isoleucine degradation II";"Methane metabolism";"3-methylbutanol biosynthesis (engineered)";"Retinol metabolism";"L-methionine degradation III";"alpha-Linolenic acid metabolism";"Metabolism of xenobiotics by cytochrome P450";"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to ethanol I" XP_030020712.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037303156.1 5 Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-201722 "RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of the beta-catenin:TCF transactivating complex" XP_030029847.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_037300713.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_030025805.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030020900.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_030021892.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_030020121.2 12 Reactome: R-HSA-1442490;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-75893;Reactome: R-HSA-982772;Reactome: R-HSA-177929;Reactome: R-HSA-2660826;Reactome: R-HSA-5362798;Reactome: R-HSA-2644606;Reactome: R-HSA-193692 "Collagen degradation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"TNF signaling";"Growth hormone receptor signaling";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Release of Hh-Np from the secreting cell";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulated proteolysis of p75NTR" XP_030024094.2 8 Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68867 "CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex" XP_030029626.2 2 Reactome: R-HSA-6785470;Reactome: R-HSA-6784531 "tRNA processing in the mitochondrion";"tRNA processing in the nucleus" XP_030023174.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030022562.2 4 KEGG: 00280+1.2.1.27;MetaCyc: PWY-5642;Reactome: R-HSA-70895;KEGG: 00640+1.2.1.27 "Valine, leucine and isoleucine degradation";"2,4-dinitrotoluene degradation";"Branched-chain amino acid catabolism";"Propanoate metabolism" XP_037300740.1 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_030022932.1 6 Reactome: R-HSA-163560;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "Triglyceride catabolism";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_037303627.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037303245.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_030030450.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_037297170.1 7 KEGG: 00983+1.1.1.205;MetaCyc: PWY-5695;Reactome: R-HSA-6798695;KEGG: 00230+1.1.1.205;Reactome: R-HSA-73817;MetaCyc: PWY-7221;MetaCyc: PWY-6596 "Drug metabolism - other enzymes";"Inosine 5'-phosphate degradation";"Neutrophil degranulation";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine nucleotides degradation I" XP_037299867.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037300734.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030021979.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" XP_030023959.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_030025538.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling" XP_037292207.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_030023743.2 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_030023435.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_037299320.1 12 MetaCyc: PWY-6803;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4 "Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Plasmalogen degradation";"Arachidonic acid metabolism" XP_037297450.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" XP_030024047.2 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_037300586.1 2 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Synthesis of PG";"Synthesis of PA" XP_037299734.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_037300775.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" XP_030038587.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_037298553.1 4 MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism" XP_030024888.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214847 "NoRC negatively regulates rRNA expression";"HATs acetylate histones" XP_030022684.1 6 MetaCyc: PWY-6854;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;Reactome: R-HSA-8862803;Reactome: R-HSA-8950505;Reactome: R-HSA-2151201 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Transcriptional activation of mitochondrial biogenesis" XP_030033197.2 9 Reactome: R-HSA-1362277;Reactome: R-HSA-6804114;Reactome: R-HSA-2173796;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-69231;Reactome: R-HSA-1362300;Reactome: R-HSA-69202 "Transcription of E2F targets under negative control by DREAM complex";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"G1/S-Specific Transcription";"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition" XP_030023882.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_037300767.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_030034124.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_030032509.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_030027160.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_030035244.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_030030928.2 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_030028990.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_037297446.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" XP_037296067.1 10 Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-8053 "Synthesis of PA";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II" XP_037294824.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6783310 "Protein ubiquitination";"Fanconi Anemia Pathway" XP_037303067.1 5 KEGG: 00740+2.7.1.26;MetaCyc: PWY-6168;MetaCyc: PWY-5523;Reactome: R-HSA-196843;MetaCyc: PWY-7863 "Riboflavin metabolism";"Flavin biosynthesis III (fungi)";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Vitamin B2 (riboflavin) metabolism";"Roseoflavin biosynthesis" XP_037292935.1 5 Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;Reactome: R-HSA-450321 "Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1" XP_037295711.1 1 Reactome: R-HSA-9022692 "Regulation of MECP2 expression and activity" XP_030027054.2 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037294693.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_030026537.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_030021458.1 1 Reactome: R-HSA-1483101 "Synthesis of PS" XP_030034453.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_030041194.2 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_037298754.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_037295450.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_030019684.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030034969.2 7 MetaCyc: PWY-7625;Reactome: R-HSA-1483226;KEGG: 00562+2.7.8.11;KEGG: 04070+2.7.8.11;MetaCyc: PWY-6352;MetaCyc: PWY-6351;KEGG: 00564+2.7.8.11 "Phosphatidylinositol biosynthesis II (eukaryotes)";"Synthesis of PI";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"3-phosphoinositide biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Glycerophospholipid metabolism" XP_037293939.1 4 MetaCyc: PWY-7511;Reactome: R-HSA-975144;Reactome: R-HSA-9020702;Reactome: R-HSA-937039 "Protein ubiquitination";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling";"IRAK1 recruits IKK complex" XP_037299141.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_030036014.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030024469.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_030025627.1 7 Reactome: R-HSA-416476;Reactome: R-HSA-114608;Reactome: R-HSA-418594;Reactome: R-HSA-381426;Reactome: R-HSA-140837;Reactome: R-HSA-375276;Reactome: R-HSA-8957275 "G alpha (q) signalling events";"Platelet degranulation";"G alpha (i) signalling events";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Intrinsic Pathway of Fibrin Clot Formation";"Peptide ligand-binding receptors";"Post-translational protein phosphorylation" XP_030020038.1 2 Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22 "Fatty acyl-CoA biosynthesis";"Fatty acid elongation" XP_030033791.2 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037302550.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-674695 "Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events" XP_037293476.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection" XP_037296245.1 182 Reactome: R-HSA-9633012;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-175474;Reactome: R-HSA-9013973;Reactome: R-HSA-69231;Reactome: R-HSA-202424;Reactome: R-HSA-912631;Reactome: R-HSA-5358346;Reactome: R-HSA-1295596;Reactome: R-HSA-5610780;Reactome: R-HSA-72689;Reactome: R-HSA-162588;Reactome: R-HSA-975956;Reactome: R-HSA-168927;Reactome: R-HSA-168928;Reactome: R-HSA-72702;Reactome: R-HSA-4641258;Reactome: R-HSA-3322077;Reactome: R-HSA-532668;Reactome: R-HSA-400253;Reactome: R-HSA-937072;Reactome: R-HSA-2565942;Reactome: R-HSA-211733;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-382556;Reactome: R-HSA-6804756;Reactome: R-HSA-5689896;Reactome: R-HSA-349425;Reactome: R-HSA-937039;Reactome: R-HSA-2173795;Reactome: R-HSA-6781827;Reactome: R-HSA-5668541;Reactome: R-HSA-937041;Reactome: R-HSA-6791226;Reactome: R-HSA-209543;Reactome: R-HSA-174154;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-2871837;Reactome: R-HSA-975957;Reactome: R-HSA-8854050;Reactome: R-HSA-5654727;Reactome: R-HSA-450302;Reactome: R-HSA-1358803;Reactome: R-HSA-174048;Reactome: R-HSA-156902;Reactome: R-HSA-917729;Reactome: R-HSA-5655862;Reactome: R-HSA-5693565;Reactome: R-HSA-2644606;Reactome: R-HSA-174184;Reactome: R-HSA-8866652;Reactome: R-HSA-8875360;Reactome: R-HSA-936440;Reactome: R-HSA-182971;Reactome: R-HSA-5675482;Reactome: R-HSA-2894862;Reactome: R-HSA-5654732;Reactome: R-HSA-1169408;Reactome: R-HSA-110314;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-68827;Reactome: R-HSA-8876493;Reactome: R-HSA-2408557;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-168638;Reactome: R-HSA-9615710;Reactome: R-HSA-975110;Reactome: R-HSA-174490;Reactome: R-HSA-6804757;Reactome: R-HSA-69017;Reactome: R-HSA-6804760;Reactome: R-HSA-3785653;Reactome: R-HSA-5687128;Reactome: R-HSA-8849469;Reactome: R-HSA-9010553;Reactome: R-HSA-901032;Reactome: R-HSA-917937;Reactome: R-HSA-69601;Reactome: R-HSA-1253288;Reactome: R-HSA-450321;Reactome: R-HSA-1234176;Reactome: R-HSA-5656121;Reactome: R-HSA-187577;Reactome: R-HSA-192823;Reactome: R-HSA-9033241;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-9637628;Reactome: R-HSA-445989;Reactome: R-HSA-8856828;Reactome: R-HSA-205043;Reactome: R-HSA-6781823;Reactome: R-HSA-195253;Reactome: R-HSA-5357905;Reactome: R-HSA-75815;Reactome: R-HSA-9613829;Reactome: R-HSA-977225;Reactome: R-HSA-110320;Reactome: R-HSA-9646399;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-6783310;Reactome: R-HSA-5205685;Reactome: R-HSA-1169091;Reactome: R-HSA-8856825;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-5696394;Reactome: R-HSA-5357956;Reactome: R-HSA-69541;Reactome: R-HSA-5675221;Reactome: R-HSA-9014325;Reactome: R-HSA-5696395;Reactome: R-HSA-3134975;Reactome: R-HSA-8941858;Reactome: R-HSA-180585;Reactome: R-HSA-6807004;Reactome: R-HSA-5689603;Reactome: R-HSA-5689901;Reactome: R-HSA-8939902;Reactome: R-HSA-2173791;Reactome: R-HSA-450408;Reactome: R-HSA-5654733;Reactome: R-HSA-8863795;Reactome: R-HSA-8939236;Reactome: R-HSA-156827;Reactome: R-HSA-5689877;Reactome: R-HSA-975163;Reactome: R-HSA-8866654;Reactome: R-HSA-2691232;Reactome: R-HSA-174178;Reactome: R-HSA-6782135;Reactome: R-HSA-5693607;Reactome: R-HSA-2122948;Reactome: R-HSA-72764;Reactome: R-HSA-937042;Reactome: R-HSA-5362768;Reactome: R-HSA-2559580;Reactome: R-HSA-5685942;Reactome: R-HSA-8948751;Reactome: R-HSA-5684264;Reactome: R-HSA-8948747;Reactome: R-HSA-72649;Reactome: R-HSA-936964;Reactome: R-HSA-110312;Reactome: R-HSA-9636383;Reactome: R-HSA-2672351;Reactome: R-HSA-5696400;Reactome: R-HSA-72695;Reactome: R-HSA-5607764;Reactome: R-HSA-2979096;Reactome: R-HSA-1236382;Reactome: R-HSA-5610783;Reactome: R-HSA-5654726;Reactome: R-HSA-9013507;Reactome: R-HSA-9645460;Reactome: R-HSA-9604323;Reactome: R-HSA-5656169;Reactome: R-HSA-2559585;Reactome: R-HSA-201681;Reactome: R-HSA-4641263;Reactome: R-HSA-2173788;Reactome: R-HSA-4641257;Reactome: R-HSA-68949;Reactome: R-HSA-6782210;Reactome: R-HSA-975144;Reactome: R-HSA-209560;Reactome: R-HSA-72706;Reactome: R-HSA-180534;Reactome: R-HSA-5696397;Reactome: R-HSA-5678895;Reactome: R-HSA-2173796;Reactome: R-HSA-5676590;Reactome: R-HSA-1799339 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Assembly Of The HIV Virion";"TICAM1-dependent activation of IRF3/IRF7";"Cyclin D associated events in G1";"Downstream TCR signaling";"Regulation of signaling by CBL";"Hedgehog ligand biogenesis";"Spry regulation of FGF signaling";"Degradation of GLI1 by the proteasome";"Formation of a pool of free 40S subunits";"Budding and maturation of HIV virion";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"TICAM1, RIP1-mediated IKK complex recruitment";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Ribosomal scanning and start codon recognition";"Degradation of DVL";"Glycogen synthesis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Circadian Clock";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Regulation of PLK1 Activity at G2/M Transition";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"ABC-family proteins mediated transport";"Regulation of TP53 Activity through Phosphorylation";"Ovarian tumor domain proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"IRAK1 recruits IKK complex";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TNFR2 non-canonical NF-kB pathway";"IKK complex recruitment mediated by RIP1";"Major pathway of rRNA processing in the nucleolus and cytosol";"p75NTR recruits signalling complexes";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"FCERI mediated NF-kB activation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of FGFR2 signaling";"activated TAK1 mediates p38 MAPK activation";"Downregulation of ERBB2:ERBB3 signaling";"APC/C:Cdc20 mediated degradation of Cyclin B";"Peptide chain elongation";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Translesion synthesis by POLK";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulators of DDX58/IFIH1 signaling";"EGFR downregulation";"Regulation of necroptotic cell death";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Negative regulation of FGFR3 signaling";"ISG15 antiviral mechanism";"Recognition of DNA damage by PCNA-containing replication complex";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"CDT1 association with the CDC6:ORC:origin complex";"InlA-mediated entry of Listeria monocytogenes into host cells";"Selenocysteine synthesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"NOD1/2 Signaling Pathway";"Late endosomal microautophagy";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Membrane binding and targetting of GAG proteins";"Regulation of TP53 Degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of TP53 Activity through Methylation";"Myoclonic epilepsy of Lafora";"MAPK6/MAPK4 signaling";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Regulation of expression of SLITs and ROBOs";"ER Quality Control Compartment (ERQC)";"Iron uptake and transport";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downregulation of ERBB4 signaling";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Translesion synthesis by POLI";"SCF(Skp2)-mediated degradation of p27/p21";"Viral mRNA Translation";"Peroxisomal protein import";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Modulation by Mtb of host immune system";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Clathrin-mediated endocytosis";"NRIF signals cell death from the nucleus";"Formation of TC-NER Pre-Incision Complex";"Degradation of beta-catenin by the destruction complex";"Regulation of TNFR1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Chaperone Mediated Autophagy";"Amyloid fiber formation";"Translesion Synthesis by POLH";"Aggrephagy";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Fanconi Anemia Pathway";"Pink/Parkin Mediated Mitophagy";"Activation of NF-kappaB in B cells";"Cargo recognition for clathrin-mediated endocytosis";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"DNA Damage Recognition in GG-NER";"TNFR1-induced NFkappaB signaling pathway";"Stabilization of p53";"Negative regulation of MAPK pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Formation of Incision Complex in GG-NER";"Regulation of innate immune responses to cytosolic DNA";"Regulation of RUNX3 expression and activity";"Vif-mediated degradation of APOBEC3G";"Negative regulation of MET activity";"UCH proteinases";"Metalloprotease DUBs";"Regulation of RUNX2 expression and activity";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Negative regulation of FGFR4 signaling";"Downregulation of ERBB2 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Josephin domain DUBs";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"E3 ubiquitin ligases ubiquitinate target proteins";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Dual incision in TC-NER";"Processing of DNA double-strand break ends";"Activated NOTCH1 Transmits Signal to the Nucleus";"Eukaryotic Translation Termination";"IRAK2 mediated activation of TAK1 complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Oxidative Stress Induced Senescence";"HDR through Homologous Recombination (HRR)";"Regulation of PTEN stability and activity";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of PTEN localization";"Translation initiation complex formation";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Translesion synthesis by REV1";"Prevention of phagosomal-lysosomal fusion";"Stimuli-sensing channels";"Dual Incision in GG-NER";"Formation of the ternary complex, and subsequently, the 43S complex";"CLEC7A (Dectin-1) signaling";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Degradation of GLI2 by the proteasome";"Negative regulation of FGFR1 signaling";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Alpha-protein kinase 1 signaling pathway";"Negative regulation of NOTCH4 signaling";"Termination of translesion DNA synthesis";"Oncogene Induced Senescence";"TCF dependent signaling in response to WNT";"Regulation of FZD by ubiquitination";"Downregulation of TGF-beta receptor signaling";"Degradation of AXIN";"Orc1 removal from chromatin";"Gap-filling DNA repair synthesis and ligation in TC-NER";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"NF-kB is activated and signals survival";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Vpu mediated degradation of CD4";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Defective CFTR causes cystic fibrosis";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NIK-->noncanonical NF-kB signaling";"SRP-dependent cotranslational protein targeting to membrane" XP_030028054.2 3 MetaCyc: PWY-1801;Reactome: R-HSA-156590;KEGG: 00680+3.1.2.12 "Formaldehyde oxidation II (glutathione-dependent)";"Glutathione conjugation";"Methane metabolism" XP_030034935.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_030024495.1 4 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis" XP_030028629.1 24 Reactome: R-HSA-400042;Reactome: R-HSA-381676;Reactome: R-HSA-8964616;Reactome: R-HSA-4086398;Reactome: R-HSA-418597;Reactome: R-HSA-420092;Reactome: R-HSA-500657;Reactome: R-HSA-428930;Reactome: R-HSA-432040;Reactome: R-HSA-416476;Reactome: R-HSA-202040;Reactome: R-HSA-418555;Reactome: R-HSA-9009391;Reactome: R-HSA-8964315;Reactome: R-HSA-392451;Reactome: R-HSA-163359;Reactome: R-HSA-392851;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-418217;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-416482;Reactome: R-HSA-392170 "Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through CDC42";"Ca2+ pathway";"G alpha (z) signalling events";"Glucagon-type ligand receptors";"Presynaptic function of Kainate receptors";"Thromboxane signalling through TP receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (q) signalling events";"G-protein activation";"G alpha (s) signalling events";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through BTK";"G beta:gamma signalling through PI3Kgamma";"Glucagon signaling in metabolic regulation";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through PLC beta";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (12/13) signalling events";"ADP signalling through P2Y purinoceptor 12" XP_030031323.1 12 Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-3371497 "MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"HCMV Early Events";"RHO GTPases Activate Formins";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_030030637.2 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_037300785.1 7 Reactome: R-HSA-373753;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-264870;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-6798695 "Nephrin family interactions";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Caspase-mediated cleavage of cytoskeletal proteins";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"Neutrophil degranulation" XP_030036281.2 7 Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.14;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00240+2.7.4.14 "Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Pyrimidine metabolism" XP_030028433.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_037301763.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_030037045.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-375165 "COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth" XP_030026747.2 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_037299423.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_030025413.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037299866.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_030020438.2 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_030033553.2 3 KEGG: 00510+2.4.1.265;Reactome: R-HSA-446193;Reactome: R-HSA-4724325 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)" XP_030030102.2 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_030019905.2 8 Reactome: R-HSA-212300;Reactome: R-HSA-8943724;Reactome: R-HSA-3214841;Reactome: R-HSA-2559580;Reactome: R-HSA-9609690;Reactome: R-HSA-5617472;Reactome: R-HSA-8953750;Reactome: R-HSA-4551638 "PRC2 methylates histones and DNA";"Regulation of PTEN gene transcription";"PKMTs methylate histone lysines";"Oxidative Stress Induced Senescence";"HCMV Early Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional Regulation by E2F6";"SUMOylation of chromatin organization proteins" XP_030034936.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_030032629.1 4 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"DARPP-32 events" XP_037296963.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_037294251.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037302085.1 4 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis" XP_037298042.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037297448.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" XP_037300953.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037295627.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030036782.2 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_030037116.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_037293726.1 8 Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852 "Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"HSF1-dependent transactivation";"mTOR signalling";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Macroautophagy" XP_030034554.2 5 Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73863 "NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination" XP_030025862.1 2 Reactome: R-HSA-1566948;Reactome: R-HSA-2243919 "Elastic fibre formation";"Crosslinking of collagen fibrils" XP_037293670.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_030028942.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_030026000.1 8 MetaCyc: PWY-7181;KEGG: 00240+3.5.4.5;MetaCyc: PWY-6556;Reactome: R-HSA-6798695;Reactome: R-HSA-73614;MetaCyc: PWY-7199;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7193 "Pyrimidine deoxyribonucleosides degradation";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage II";"Neutrophil degranulation";"Pyrimidine salvage";"Pyrimidine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I" XP_030028473.1 7 KEGG: 00020+1.2.4.1;KEGG: 00010+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-70268;Reactome: R-HSA-389661;Reactome: R-HSA-204174 "Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_030029999.2 7 MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-5469 "Justicidin B biosynthesis";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Sesamin biosynthesis" XP_030023177.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037296456.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_030020289.2 17 Reactome: R-HSA-5689880;Reactome: R-HSA-5357956;Reactome: R-HSA-9645460;Reactome: R-HSA-445989;Reactome: R-HSA-975163;Reactome: R-HSA-9014325;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-450302;Reactome: R-HSA-937042;Reactome: R-HSA-450321;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-168638;Reactome: R-HSA-9020702;Reactome: R-HSA-937072;Reactome: R-HSA-4086398 "Ub-specific processing proteases";"TNFR1-induced NFkappaB signaling pathway";"Alpha-protein kinase 1 signaling pathway";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"NOD1/2 Signaling Pathway";"Interleukin-1 signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Ca2+ pathway" XP_030040217.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037301600.1 27 Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-4570464 "Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins" XP_037302620.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_037300724.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_030023466.2 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_030032572.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_030020296.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037300392.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037294849.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030032393.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_030025404.2 7 Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-69202 "G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition" XP_037296650.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" XP_037292858.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030033313.2 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_030035780.2 6 Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-69052 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA";"Switching of origins to a post-replicative state" XP_030022950.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-9010553 "Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs" XP_030024451.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_030023803.2 13 Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Eukaryotic Translation Termination" XP_037297526.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380284 "Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_037293969.1 33 Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-4551638;Reactome: R-HSA-2467813;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-168325;Reactome: R-HSA-9648025;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-141444;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-180746;Reactome: R-HSA-159231;Reactome: R-HSA-68877 "SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"SUMOylation of chromatin organization proteins";"Separation of Sister Chromatids";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Viral Messenger RNA Synthesis";"EML4 and NUDC in mitotic spindle formation";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear import of Rev protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Mitotic Prometaphase" XP_030023672.1 3 KEGG: 00240+1.3.5.2;MetaCyc: PWY-5686;Reactome: R-HSA-500753 "Pyrimidine metabolism";"UMP biosynthesis I";"Pyrimidine biosynthesis" XP_037301702.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-1663150 "Glycosphingolipid metabolism";"The activation of arylsulfatases" XP_030022792.1 3 Reactome: R-HSA-2022854;Reactome: R-HSA-5173105;Reactome: R-HSA-5083627 "Keratan sulfate biosynthesis";"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6" XP_037296496.1 6 Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-428930 "Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor" XP_030034769.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030029248.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_037295916.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037295902.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030021205.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012 "L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_037301108.1 1 Reactome: R-HSA-975578 "Reactions specific to the complex N-glycan synthesis pathway" XP_037294949.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037295760.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037294601.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037297196.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380284 "Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_030028916.1 3 MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077 "Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen synthesis" XP_030033223.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_037302147.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_030027592.2 2 MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" XP_030024409.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_030027332.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706 "L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_030026016.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_030028586.2 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_037295848.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_030023246.1 4 Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_037302271.1 5 KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;MetaCyc: PWY-6558 "Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)" XP_030023725.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947 "Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription" XP_030022412.2 6 Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-380994 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_037299474.1 5 KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661 "Lysine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation" XP_030020139.2 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037297538.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004 "Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity" XP_030024632.1 1 Reactome: R-HSA-1614603 "Cysteine formation from homocysteine" XP_037292280.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_030041102.2 10 Reactome: R-HSA-201722;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "Formation of the beta-catenin:TCF transactivating complex";"Thermogenesis";"Human cytomegalovirus infection";"HATs acetylate histones";"Human immunodeficiency virus 1 infection";"Ub-specific processing proteases";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway" XP_037296165.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037302568.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_030025976.2 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_030034877.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_037296148.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037294252.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037296151.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030026767.1 11 MetaCyc: PWY-6963;KEGG: 00630+6.3.1.2;MetaCyc: PWY-5675;MetaCyc: PWY-381;Reactome: R-HSA-8964539;MetaCyc: PWY-6964;KEGG: 00220+6.3.1.2;Reactome: R-HSA-210455;MetaCyc: PWY-6549;KEGG: 00250+6.3.1.2;KEGG: 00910+6.3.1.2 "Ammonia assimilation cycle I";"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction V (assimilatory)";"Nitrate reduction II (assimilatory)";"Glutamate and glutamine metabolism";"Ammonia assimilation cycle II";"Arginine biosynthesis";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"L-glutamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism" XP_030029496.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_030029400.2 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_030027792.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037294966.1 7 Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-5083628;Reactome: R-HSA-3000178;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;Reactome: R-HSA-9010553 "Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"ECM proteoglycans";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Regulation of expression of SLITs and ROBOs" XP_030030470.1 5 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-112409;Reactome: R-HSA-5675221 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"RAF-independent MAPK1/3 activation";"Negative regulation of MAPK pathway" XP_037297240.1 3 Reactome: R-HSA-193681;Reactome: R-HSA-1660662;Reactome: R-HSA-5626978 "Ceramide signalling";"Glycosphingolipid metabolism";"TNFR1-mediated ceramide production" XP_037294964.1 7 Reactome: R-HSA-5083628;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-9010553;Reactome: R-HSA-5083633;Reactome: R-HSA-3000178;Reactome: R-HSA-5173105 "Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"Regulation of expression of SLITs and ROBOs";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"ECM proteoglycans";"O-linked glycosylation" XP_030041170.2 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_030033648.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_030025018.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_030024195.2 11 MetaCyc: PWY-5675;MetaCyc: PWY-381;MetaCyc: PWY-6963;KEGG: 00630+6.3.1.2;Reactome: R-HSA-210455;MetaCyc: PWY-6549;KEGG: 00220+6.3.1.2;KEGG: 00250+6.3.1.2;KEGG: 00910+6.3.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-6964 "Nitrate reduction V (assimilatory)";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle I";"Glyoxylate and dicarboxylate metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"L-glutamine biosynthesis III";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Glutamate and glutamine metabolism";"Ammonia assimilation cycle II" XP_030022681.1 4 Reactome: R-HSA-73817;KEGG: 00230+6.3.5.2;KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221 "Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis" XP_030040075.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030028799.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_030037787.2 15 Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-2559580;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-9029569 "Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"Oxidative Stress Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_030022233.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037301517.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_030031115.2 8 Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68867 "CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex" XP_037293970.1 4 MetaCyc: PWY-6823;KEGG: 00790+2.8.1.12;Reactome: R-HSA-947581;MetaCyc: PWY-7887 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation" XP_030022741.2 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" XP_030025150.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_037297531.1 6 Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817 "Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_030031631.2 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_030034468.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_037298508.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037300466.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_030022145.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_037294837.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_030026036.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037303643.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_030028987.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_030033752.1 3 Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597 "Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"G alpha (z) signalling events" XP_030019712.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_030032071.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_030028126.2 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_030024077.2 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_037300180.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_030026999.2 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037294239.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_030036481.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706 "Eukaryotic Translation Termination";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_030024003.2 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_037293633.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_030039892.2 2 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Synthesis of PG";"Synthesis of PA" XP_030041046.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_030026555.2 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_030023262.2 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_030028491.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037298487.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_037296700.1 4 Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" XP_037297644.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_030040979.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_037301704.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7619 "Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis" XP_037294608.1 10 MetaCyc: PWY-7559;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-7112;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842 "Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Glutathione-mediated detoxification II" XP_037300405.1 9 Reactome: R-HSA-3656237;Reactome: R-HSA-975634;Reactome: R-HSA-2024096;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801;Reactome: R-HSA-1971475;Reactome: R-HSA-2022928;Reactome: R-HSA-3560783;Reactome: R-HSA-4420332 "Defective EXT2 causes exostoses 2";"Retinoid metabolism and transport";"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG biosynthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1" XP_037292705.1 31 MetaCyc: PWY-7746;MetaCyc: PWY-6113;MetaCyc: PWY-5966-1;MetaCyc: PWY-8012;MetaCyc: PWY-8047;MetaCyc: PWY-7664;MetaCyc: PWY-6799;MetaCyc: PWY-4381;Reactome: R-HSA-163765;MetaCyc: PWY-6519;MetaCyc: PWY-5367;MetaCyc: PWY-6282;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8049;Reactome: R-HSA-9029558;MetaCyc: PWY-7723;MetaCyc: PWY-5971;MetaCyc: PWY-5994;MetaCyc: PWY-7388;Reactome: R-HSA-199220;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7663;MetaCyc: PWY-5366;MetaCyc: PWY-5147;MetaCyc: PWYG-321;Reactome: R-HSA-2426168;MetaCyc: PWY-5142;MetaCyc: PWY-5989;Reactome: R-HSA-75105;MetaCyc: PWY-5973;MetaCyc: PWY-7858 "Mycobacterial sulfolipid biosynthesis";"Superpathway of mycolate biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Mupirocin biosynthesis";"Bryostatin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acid biosynthesis initiation (bacteria and plants)";"ChREBP activates metabolic gene expression";"8-amino-7-oxononanoate biosynthesis I";"Petroselinate biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Biotin metabolism";"Pederin biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Bacterial bioluminescence";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Vitamin B5 (pantothenate) metabolism";"Fatty acid biosynthesis";"Gondoate biosynthesis (anaerobic)";"Palmitoleate biosynthesis II (plants and bacteria)";"Oleate biosynthesis I (plants)";"";"Activation of gene expression by SREBF (SREBP)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Stearate biosynthesis II (bacteria and plants)";"Fatty acyl-CoA biosynthesis";"Cis-vaccenate biosynthesis";"(5Z)-dodecenoate biosynthesis II" XP_037294706.1 13 Reactome: R-HSA-381676;Reactome: R-HSA-4086398;Reactome: R-HSA-114508;Reactome: R-HSA-139853;Reactome: R-HSA-2029485;Reactome: R-HSA-112043;Reactome: R-HSA-5607763;Reactome: R-HSA-2871809;Reactome: R-HSA-5578775;Reactome: R-HSA-5218921;Reactome: R-HSA-1489509;Reactome: R-HSA-983695;Reactome: R-HSA-422356 "Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway";"Effects of PIP2 hydrolysis";"Elevation of cytosolic Ca2+ levels";"Role of phospholipids in phagocytosis";"PLC beta mediated events";"CLEC7A (Dectin-1) induces NFAT activation";"FCERI mediated Ca+2 mobilization";"Ion homeostasis";"VEGFR2 mediated cell proliferation";"DAG and IP3 signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Regulation of insulin secretion" XP_030020704.1 7 Reactome: R-HSA-1660499;KEGG: 00562+2.7.1.67;MetaCyc: PWY-6352;MetaCyc: PWY-6351;KEGG: 04070+2.7.1.67;Reactome: R-HSA-1660514;Reactome: R-HSA-1660516 "Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane" XP_030027360.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037297350.1 2 Reactome: R-HSA-3000178;MetaCyc: PWY-7511 "ECM proteoglycans";"Protein ubiquitination" XP_037302434.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037295302.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_030020989.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037300003.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_030031084.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037302192.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_030037133.2 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_030029156.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823 "Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex" XP_030030021.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_030029868.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_030022143.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_037296851.1 8 MetaCyc: PWY-7717;MetaCyc: PWY-7765;MetaCyc: PWY-5651;MetaCyc: PWY-7734;MetaCyc: PWY-6309;MetaCyc: PWY-7733;KEGG: 00380+3.5.1.9;KEGG: 00630+3.5.1.9 "3-hydroxy-4-methyl-anthranilate biosynthesis I";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Quinoxaline-2-carboxylate biosynthesis";"L-tryptophan degradation XI (mammalian, via kynurenine)";"3-hydroxyquinaldate biosynthesis";"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism" XP_037292758.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_030032994.1 12 Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-6804756;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167152 "Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat" XP_030019853.1 56 Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins" XP_030025865.1 2 Reactome: R-HSA-2243919;Reactome: R-HSA-1566948 "Crosslinking of collagen fibrils";"Elastic fibre formation" XP_037295804.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037294788.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030029246.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_030030865.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037295580.1 10 KEGG: 05165+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 05163+2.7.1.153;KEGG: 04070+2.7.1.153;MetaCyc: PWY-6352;KEGG: 04150+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 05170+2.7.1.153;KEGG: 00562+2.7.1.153;KEGG: 04151+2.7.1.153 "Human papillomavirus infection";"Synthesis of PIPs at the plasma membrane";"Human cytomegalovirus infection";"Phosphatidylinositol signaling system";"3-phosphoinositide biosynthesis";"mTOR signaling pathway";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human immunodeficiency virus 1 infection";"Inositol phosphate metabolism";"PI3K-Akt signaling pathway" XP_030030511.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_030026291.1 10 MetaCyc: PWY-7184;KEGG: 00670+2.1.1.45;MetaCyc: PWY-7199;MetaCyc: PWY-7198;Reactome: R-HSA-499943;MetaCyc: PWY-7187;MetaCyc: PWY-7210;KEGG: 00240+2.1.1.45;MetaCyc: PWY-3841;Reactome: R-HSA-69205 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"One carbon pool by folate";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Folate transformations II (plants)";"G1/S-Specific Transcription" XP_030041148.2 6 Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex" XP_030021800.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_030037378.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_030021645.2 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_030021546.2 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037295160.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" XP_030038321.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037297199.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes" XP_037294502.1 3 MetaCyc: PWY-7999;KEGG: 00130+1.17.4.4;Reactome: R-HSA-6806664 "Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Metabolism of vitamin K" XP_037299735.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_037300333.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_030032220.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_030041183.2 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_030040998.2 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_030038436.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030032580.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_030024951.2 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_030034145.2 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037296035.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_030032034.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_037298516.1 10 KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-7385 "Methane metabolism";"Pentose phosphate pathway";"Galactose metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)" XP_030021237.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_030022503.1 4 Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437 "UCH proteinases";"HATs acetylate histones";"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation" XP_037299515.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030033312.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_030033588.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs" XP_030040484.1 10 Reactome: R-HSA-9627069;Reactome: R-HSA-111457;Reactome: R-HSA-5628897;Reactome: R-HSA-111458;Reactome: R-HSA-3299685;Reactome: R-HSA-111459;Reactome: R-HSA-111464;Reactome: R-HSA-2151201;Reactome: R-HSA-111463;Reactome: R-HSA-611105 "Regulation of the apoptosome activity";"Release of apoptotic factors from the mitochondria";"TP53 Regulates Metabolic Genes";"Formation of apoptosome";"Detoxification of Reactive Oxygen Species";"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Transcriptional activation of mitochondrial biogenesis";"SMAC (DIABLO) binds to IAPs";"Respiratory electron transport" XP_030025927.1 12 MetaCyc: PWY-6527;KEGG: 00561+2.7.7.9;KEGG: 00040+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-7343;KEGG: 00500+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-7238;MetaCyc: PWY-7817;KEGG: 00520+2.7.7.9;Reactome: R-HSA-3322077;KEGG: 00052+2.7.7.9 "Stachyose degradation";"Glycerolipid metabolism";"Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucose biosynthesis I";"Starch and sucrose metabolism";"Sucrose degradation II (sucrose synthase)";"Sucrose biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Amino sugar and nucleotide sugar metabolism";"Glycogen synthesis";"Galactose metabolism" XP_030037377.1 7 MetaCyc: PWY-7198;KEGG: 00230+3.6.1.15;KEGG: 00730+3.6.1.15;MetaCyc: PWY-7185;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-6545 "Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Thiamine metabolism";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" XP_030021515.1 5 Reactome: R-HSA-73817;MetaCyc: PWY-6277;MetaCyc: PWY-6122;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6121 "Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I" XP_030021916.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_037301710.1 5 MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)" XP_037297192.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-5620912 "Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane" XP_030040994.2 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_030021365.2 5 KEGG: 00730+2.2.1.7;MetaCyc: PWY-7560;MetaCyc: PWY-6892;MetaCyc: PWY-6891;KEGG: 00900+2.2.1.7 "Thiamine metabolism";"Methylerythritol phosphate pathway II";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiazole biosynthesis II (aerobic bacteria)";"Terpenoid backbone biosynthesis" XP_030035950.2 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037301893.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_037293028.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037299986.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_030033193.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037292994.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_030025082.2 2 Reactome: R-HSA-6811436;Reactome: R-HSA-8876198 "COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_037302662.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" XP_030032534.1 7 KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-210500;KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897 "D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"Glutamate Neurotransmitter Release Cycle";"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis";"TP53 Regulates Metabolic Genes" XP_037302413.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_030021963.1 3 Reactome: R-HSA-6804760;Reactome: R-HSA-2299718;Reactome: R-HSA-3214841 "Regulation of TP53 Activity through Methylation";"Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines" XP_037300208.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_030028636.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037297453.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037296209.1 10 KEGG: 05170+2.7.11.1;Reactome: R-HSA-442742;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Human cytomegalovirus infection";"Thermogenesis";"RSK activation";"mTOR signaling pathway";"Relaxin signaling pathway";"Recycling pathway of L1";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_037296153.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037294171.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_030028052.2 3 MetaCyc: PWY-1801;KEGG: 00680+3.1.2.12;Reactome: R-HSA-156590 "Formaldehyde oxidation II (glutathione-dependent)";"Methane metabolism";"Glutathione conjugation" XP_037297276.1 8 KEGG: 00030+5.3.1.6;Reactome: R-HSA-71336;Reactome: R-HSA-5659996;MetaCyc: PWY-5723;KEGG: 00710+5.3.1.6;KEGG: 00051+5.3.1.6;Reactome: R-HSA-6791461;MetaCyc: PWY-1861 "Pentose phosphate pathway";"Pentose phosphate pathway";"RPIA deficiency: failed conversion of R5P to RU5P";"Rubisco shunt";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"RPIA deficiency: failed conversion of RU5P to R5P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" XP_030025864.1 2 Reactome: R-HSA-1566948;Reactome: R-HSA-2243919 "Elastic fibre formation";"Crosslinking of collagen fibrils" XP_037301611.1 2 Reactome: R-HSA-6802953;Reactome: R-HSA-5658442 "RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs" XP_030023592.2 1 Reactome: R-HSA-75153 "Apoptotic execution phase" XP_037296806.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_037300031.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_030024196.1 7 Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-73980 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination" XP_030025218.1 5 KEGG: 00785+2.3.1.181;KEGG: 00785+6.3.1.20;MetaCyc: PWY-6987;MetaCyc: PWY-7382;Reactome: R-HSA-389661 "Lipoic acid metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation" XP_037302683.1 4 Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-381771 "Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" XP_037303290.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_030029263.2 6 Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-380994 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_030035902.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037292844.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_030030595.2 3 Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5655862 "Translesion synthesis by POLI";"Translesion synthesis by REV1";"Translesion synthesis by POLK" XP_030034212.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_030031418.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_030022408.2 5 Reactome: R-HSA-209560;Reactome: R-HSA-5205685;Reactome: R-HSA-209543;Reactome: R-HSA-9020702;Reactome: R-HSA-205043 "NF-kB is activated and signals survival";"Pink/Parkin Mediated Mitophagy";"p75NTR recruits signalling complexes";"Interleukin-1 signaling";"NRIF signals cell death from the nucleus" XP_037303130.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_037296627.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_030028078.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_030023883.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_030029565.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037298988.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_030040351.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_030019670.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_030037986.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72706 "Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_030019565.2 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_030040086.2 6 MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system" XP_037297495.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_030020939.1 3 MetaCyc: PWY-7800;Reactome: R-HSA-2514859;MetaCyc: PWY-7799 "Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)" XP_030032411.2 10 Reactome: R-HSA-2142789;MetaCyc: PWY-5895;MetaCyc: PWY-5892;MetaCyc: PWY-7996;MetaCyc: PWY-5890;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5844;MetaCyc: PWY-5839;MetaCyc: PWY-5891;MetaCyc: PWY-5849 "Ubiquinol biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-10 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-6 biosynthesis" XP_037295758.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_037295659.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030026579.2 5 Reactome: R-HSA-430039;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-380994 "mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_030021225.1 3 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843 "Purine metabolism";"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis" XP_030024814.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_037300270.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_030021648.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037299249.1 18 MetaCyc: PWY-5913;MetaCyc: PWY-5690;KEGG: 00020+2.3.3.8;Reactome: R-HSA-163765;MetaCyc: PWY-5537;MetaCyc: PWY-6728;MetaCyc: PWY-6969;Reactome: R-HSA-75105;MetaCyc: PWY-5172;Reactome: R-HSA-6798695;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5538;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;KEGG: 00720+2.3.3.8;KEGG: 00720+6.2.1.5 "Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"ChREBP activates metabolic gene expression";"Pyruvate fermentation to acetate V";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Fatty acyl-CoA biosynthesis";"Acetyl-coa biosynthesis III (from citrate)";"Neutrophil degranulation";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"Pyruvate fermentation to acetate VI";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes" XP_037301482.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_030021665.1 1 Reactome: R-HSA-189451 "Heme biosynthesis" XP_037295025.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037299677.1 2 Reactome: R-HSA-877312;Reactome: R-HSA-6807004 "Regulation of IFNG signaling";"Negative regulation of MET activity" XP_030021412.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030023469.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_037295746.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030022674.1 3 KEGG: 00350+3.7.1.2;Reactome: R-HSA-8963684;KEGG: 00643+3.7.1.2 "Tyrosine metabolism";"Tyrosine catabolism";"Styrene degradation" XP_037297537.1 3 Reactome: R-HSA-913709;KEGG: 00510+2.4.1.117;Reactome: R-HSA-480985 "O-linked glycosylation of mucins";"N-Glycan biosynthesis";"Synthesis of dolichyl-phosphate-glucose" XP_030032691.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037301335.1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_037302677.1 4 MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism" XP_030023117.1 9 Reactome: R-HSA-1475029;MetaCyc: PWY-5743;MetaCyc: PWY-7115;MetaCyc: PWY-6142;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-7117 "Reversible hydration of carbon dioxide";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type" XP_030034767.2 57 Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-1236978;Reactome: R-HSA-174184 "NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A" XP_030034799.1 3 Reactome: R-HSA-5628897;KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "TP53 Regulates Metabolic Genes";"Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_037294669.1 27 Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-170822 "tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein" XP_030028762.2 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_030040850.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-975957 "mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_030037470.1 3 Reactome: R-HSA-8951664;Reactome: R-HSA-349425;MetaCyc: PWY-7511 "Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Protein ubiquitination" XP_030023045.1 6 Reactome: R-HSA-74259;MetaCyc: PWY-6606;MetaCyc: PWY-5497;KEGG: 00230+3.5.4.3;MetaCyc: PWY-7442;MetaCyc: PWY-6608 "Purine catabolism";"Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Purine metabolism";"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation III" XP_037303051.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_030022409.2 5 Reactome: R-HSA-209560;Reactome: R-HSA-5205685;Reactome: R-HSA-209543;Reactome: R-HSA-9020702;Reactome: R-HSA-205043 "NF-kB is activated and signals survival";"Pink/Parkin Mediated Mitophagy";"p75NTR recruits signalling complexes";"Interleukin-1 signaling";"NRIF signals cell death from the nucleus" XP_030036305.2 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_030023312.2 9 Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_037295351.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_037301544.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037292614.1 4 Reactome: R-HSA-70688;MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922 "Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis" XP_037297295.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_030035223.2 3 Reactome: R-HSA-2024096;Reactome: R-HSA-2024101;Reactome: R-HSA-2206296 "HS-GAG degradation";"CS/DS degradation";"MPS II - Hunter syndrome" XP_030022263.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037300252.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037292474.1 2 Reactome: R-HSA-442982;Reactome: R-HSA-5673001 "Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade" XP_030028242.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037299977.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_037302022.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_030035595.2 3 Reactome: R-HSA-9609690;Reactome: R-HSA-6804757;Reactome: R-HSA-3899300 "HCMV Early Events";"Regulation of TP53 Degradation";"SUMOylation of transcription cofactors" XP_030036997.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_030035778.2 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037298929.1 3 Reactome: R-HSA-430039;Reactome: R-HSA-450385;Reactome: R-HSA-450513 "mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_037301921.1 4 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"DARPP-32 events" XP_037303580.1 56 Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858 "Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"UCH proteinases";"Vpu mediated degradation of CD4";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity" XP_030029416.2 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_030021644.1 26 Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-389977;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-389960;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833 "Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Post-chaperonin tubulin folding pathway";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Kinesins";"Mitotic Prometaphase";"Formation of tubulin folding intermediates by CCT/TriC";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"HCMV Early Events";"MHC class II antigen presentation";"Cilium Assembly" XP_030035261.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_030026788.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037299131.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-8041;Reactome: R-HSA-75876 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs" XP_030023786.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_030029302.1 5 Reactome: R-HSA-73614;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73621;MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3 "Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism" XP_030032419.1 14 Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-5620924;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-1632852;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Intraflagellar transport";"Mitotic Prometaphase";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HCMV Early Events";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Macroautophagy";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_030020817.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037295080.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037296320.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_030040673.2 5 Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-109704;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001 "Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K Cascade";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade" XP_037292530.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259 "Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism" XP_030040383.1 5 Reactome: R-HSA-373080;Reactome: R-HSA-5610787;Reactome: R-HSA-5632684;Reactome: R-HSA-5620922;Reactome: R-HSA-5635838 "Class B/2 (Secretin family receptors)";"Hedgehog 'off' state";"Hedgehog 'on' state";"BBSome-mediated cargo-targeting to cilium";"Activation of SMO" XP_030021836.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037294100.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_030033444.2 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_037300974.1 15 Reactome: R-HSA-167243;Reactome: R-HSA-2173796;Reactome: R-HSA-6807505;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-176034 "Tat-mediated HIV elongation arrest and recovery";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RNA polymerase II transcribes snRNA genes";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Interactions of Tat with host cellular proteins" XP_030027658.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_037302713.1 11 KEGG: 00240+3.1.3.5;MetaCyc: PWY-6606;MetaCyc: PWY-6596;MetaCyc: PWY-6608;KEGG: 00230+3.1.3.5;MetaCyc: PWY-5695;KEGG: 00760+3.1.3.5;MetaCyc: PWY-5381;MetaCyc: PWY-7185;MetaCyc: PWY-7821;MetaCyc: PWY-6607 "Pyrimidine metabolism";"Guanosine nucleotides degradation II";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation III";"Purine metabolism";"Inosine 5'-phosphate degradation";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"UTP and CTP dephosphorylation I";"Tunicamycin biosynthesis";"Guanosine nucleotides degradation I" XP_037295127.1 2 Reactome: R-HSA-9033500;Reactome: R-HSA-9033241 "TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import" XP_030026010.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394 "Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER" XP_037302936.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_037296826.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_037292832.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_030020244.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037294942.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037292642.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037293966.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_037300613.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037302257.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72695 "Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex" XP_037300458.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030040871.1 3 Reactome: R-HSA-6806664;KEGG: 00130+1.17.4.4;MetaCyc: PWY-7999 "Metabolism of vitamin K";"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle" XP_030023812.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_030024714.2 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8869496 "Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" XP_030020897.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037299708.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-2173788 "UCH proteinases";"Downregulation of TGF-beta receptor signaling" XP_037295245.1 34 Reactome: R-HSA-4615885;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-3232142;Reactome: R-HSA-2467813;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-168325;Reactome: R-HSA-9648025;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-9639288;Reactome: R-HSA-4551638;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-141444;Reactome: R-HSA-168276;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-159231;Reactome: R-HSA-68877;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-159236 "SUMOylation of DNA replication proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of ubiquitinylation proteins";"Separation of Sister Chromatids";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Viral Messenger RNA Synthesis";"EML4 and NUDC in mitotic spindle formation";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"Amino acids regulate mTORC1";"SUMOylation of chromatin organization proteins";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NS1 Mediated Effects on Host Pathways";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Mitotic Prometaphase";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_037298221.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037301880.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037301440.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation" XP_037296444.1 6 MetaCyc: PWY-2221;KEGG: 00030+3.1.1.17;MetaCyc: PWY-5530;KEGG: 00930+3.1.1.17;MetaCyc: PWY-7165;KEGG: 00053+3.1.1.17 "Entner-Doudoroff pathway III (semi-phosphorylative)";"Pentose phosphate pathway";"Sorbitol biosynthesis II";"Caprolactam degradation";"L-ascorbate biosynthesis VI (engineered pathway)";"Ascorbate and aldarate metabolism" XP_030029417.2 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_030021841.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_030041081.2 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_030029228.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037303355.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_030026870.2 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037292426.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_037299516.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037295390.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_030026974.2 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_037292362.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_030021961.1 11 Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607 "Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends" XP_030031589.2 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_030032035.1 6 Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-6922;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6344;MetaCyc: PWY-3341 "Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)" XP_030025403.2 7 Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-69205 "Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription" XP_037294277.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_030020170.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037297139.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037302217.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037299093.1 12 Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-8854518;Reactome: R-HSA-381038;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380284 "MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"AURKA Activation by TPX2";"XBP1(S) activates chaperone genes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_030027471.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037297729.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030029852.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037294301.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_030020767.2 2 Reactome: R-HSA-6807004;Reactome: R-HSA-877312 "Negative regulation of MET activity";"Regulation of IFNG signaling" XP_037295271.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320 "Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes" XP_037293993.1 11 Reactome: R-HSA-174430;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-68962;Reactome: R-HSA-5651801;Reactome: R-HSA-68952 "Telomere C-strand synthesis initiation";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of the pre-replicative complex";"PCNA-Dependent Long Patch Base Excision Repair";"DNA replication initiation" XP_037301765.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_037300770.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_030020651.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_030033346.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_030023500.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_030021008.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_037302645.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" XP_030019733.1 13 Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-5674400;Reactome: R-HSA-3371571;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-5218920;Reactome: R-HSA-1632852;Reactome: R-HSA-1257604;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897 "mTORC1-mediated signalling";"mTOR signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"HSF1-dependent transactivation";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"VEGFR2 mediated vascular permeability";"Macroautophagy";"PIP3 activates AKT signaling";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes" XP_030020564.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037292996.1 3 Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-110328 "Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" XP_037297965.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-192823 "Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation" XP_037295057.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_030038161.1 3 Reactome: R-HSA-156590;Reactome: R-HSA-204174;Reactome: R-HSA-8963684 "Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism" XP_037302574.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_030028413.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_030025405.2 7 Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277 "Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"G1/S-Specific Transcription";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex" XP_037301824.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_037302583.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_030037859.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030028607.2 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_037297231.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037301363.1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_037302242.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_030031478.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_037298567.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_030028465.1 5 KEGG: 00600+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22 "Sphingolipid metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Galactose metabolism" XP_030028742.2 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_037301243.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_037295720.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037302443.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_030040207.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030036688.1 16 Reactome: R-HSA-141430;Reactome: R-HSA-174048;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-8853884;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-2559582;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-176408 "Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"Transcriptional Regulation by VENTX";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase" XP_030025754.1 5 Reactome: R-HSA-1834941;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-3134975;Reactome: R-HSA-3249367 "STING mediated induction of host immune responses";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"Regulation of innate immune responses to cytosolic DNA";"STAT6-mediated induction of chemokines" XP_030035437.1 24 Reactome: R-HSA-9634635;Reactome: R-HSA-165158;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-389357;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1257604;KEGG: 04150+2.7.11.1;Reactome: R-HSA-444257;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-202424;Reactome: R-HSA-354192;KEGG: 05170+2.7.11.1;Reactome: R-HSA-114604;Reactome: R-HSA-5674400;Reactome: R-HSA-5625740;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5218921;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2730905;Reactome: R-HSA-5218920 "Estrogen-stimulated signaling through PRKCZ";"Activation of AKT2";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"CD28 dependent PI3K/Akt signaling";"Human papillomavirus infection";"PIP3 activates AKT signaling";"mTOR signaling pathway";"RSK activation";"Human cytomegalovirus infection";"Thermogenesis";"G beta:gamma signalling through PI3Kgamma";"Downstream TCR signaling";"Integrin signaling";"Human immunodeficiency virus 1 infection";"GPVI-mediated activation cascade";"Constitutive Signaling by AKT1 E17K in Cancer";"RHO GTPases activate PKNs";"PI3K-Akt signaling pathway";"Regulation of TP53 Degradation";"VEGFR2 mediated cell proliferation";"Relaxin signaling pathway";"Role of LAT2/NTAL/LAB on calcium mobilization";"VEGFR2 mediated vascular permeability" XP_037298153.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030040157.2 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_030029624.2 2 Reactome: R-HSA-6785470;Reactome: R-HSA-6784531 "tRNA processing in the mitochondrion";"tRNA processing in the nucleus" XP_037296642.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism" XP_030036056.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_037296979.1 2 Reactome: R-HSA-190373;Reactome: R-HSA-5654726 "FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling" XP_037294616.1 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_037297447.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" XP_037301460.1 3 Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-381038 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"XBP1(S) activates chaperone genes" XP_030021591.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_037294806.1 9 Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-5674135;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-114608;Reactome: R-HSA-6802946;Reactome: R-HSA-445355;Reactome: R-HSA-6802948 "Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Platelet degranulation";"Signaling by moderate kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants" XP_037299895.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-6804758 "RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation" XP_030036907.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_030033764.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_030025609.2 5 Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_037302527.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex" XP_037298251.1 12 Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-447038;Reactome: R-HSA-438066;MetaCyc: PWY-7221;Reactome: R-HSA-399719;Reactome: R-HSA-451308;Reactome: R-HSA-5673001 "Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"NrCAM interactions";"Unblocking of NMDA receptors, glutamate binding and activation";"Guanosine ribonucleotides de novo biosynthesis";"Trafficking of AMPA receptors";"Activation of Ca-permeable Kainate Receptor";"RAF/MAP kinase cascade" XP_037295870.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_030034204.2 10 KEGG: 00510+2.4.1.83;Reactome: R-HSA-4719377;MetaCyc: PWY-7921;Reactome: R-HSA-4717374;MetaCyc: PWY-7661;MetaCyc: PWY-7979;Reactome: R-HSA-162699;Reactome: R-HSA-4719360;MetaCyc: PWY-7922;Reactome: R-HSA-913709 "N-Glycan biosynthesis";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Protein O-mannosylation I (yeast)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Protein N-glycosylation (Haloferax volcanii)";"Protein O-mannosylation III (mammals, core M3)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"O-linked glycosylation of mucins" XP_030024310.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_030021930.1 5 Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-3214815;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606 "NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_037295311.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_030034329.1 1 Reactome: R-HSA-446203 "Asparagine N-linked glycosylation" XP_037299899.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones" XP_030023840.2 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_030027942.1 11 MetaCyc: PWY-6596;MetaCyc: PWY-6608;KEGG: 00230+3.1.3.5;MetaCyc: PWY-5695;MetaCyc: PWY-5381;KEGG: 00760+3.1.3.5;MetaCyc: PWY-7185;MetaCyc: PWY-7821;MetaCyc: PWY-6607;KEGG: 00240+3.1.3.5;MetaCyc: PWY-6606 "Adenosine nucleotides degradation I";"Guanosine nucleotides degradation III";"Purine metabolism";"Inosine 5'-phosphate degradation";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"UTP and CTP dephosphorylation I";"Tunicamycin biosynthesis";"Guanosine nucleotides degradation I";"Pyrimidine metabolism";"Guanosine nucleotides degradation II" XP_030021385.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7 "Mitochondrial translation initiation";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_030029893.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030038561.2 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_037295161.1 7 Reactome: R-HSA-69205;Reactome: R-HSA-69231;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-6804114;Reactome: R-HSA-2173796;Reactome: R-HSA-1362300 "G1/S-Specific Transcription";"Cyclin D associated events in G1";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1" XP_030038802.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_037298512.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_030023884.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_037295012.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_030030926.2 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_037296737.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_037297306.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037302321.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_030022076.1 3 Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691 "Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_030029300.1 5 Reactome: R-HSA-73614;Reactome: R-HSA-73621;KEGG: 00983+2.4.2.3;KEGG: 00240+2.4.2.3;MetaCyc: PWY-5532 "Pyrimidine salvage";"Pyrimidine catabolism";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)" XP_037300032.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_037294768.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_030028642.2 2 MetaCyc: PWY-6938;Reactome: R-HSA-430039 "NADH repair";"mRNA decay by 5' to 3' exoribonuclease" XP_030041169.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_030038257.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis" XP_030028634.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_030040023.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_037296805.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037298096.1 14 Reactome: R-HSA-434316;MetaCyc: PWY-6351;Reactome: R-HSA-418217;MetaCyc: PWY-6367;Reactome: R-HSA-399997;Reactome: R-HSA-416476;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-112043;Reactome: R-HSA-4086398;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-500657;Reactome: R-HSA-1855204 "Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G beta:gamma signalling through PLC beta";"D-myo-inositol-5-phosphate metabolism";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events";"Ca2+ pathway";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Presynaptic function of Kainate receptors";"Synthesis of IP3 and IP4 in the cytosol" XP_030023059.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037297999.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_030034786.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_030030606.2 7 Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-1442490;Reactome: R-HSA-2122948;Reactome: R-HSA-177929 "Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Collagen degradation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Signaling by EGFR" XP_030031976.1 10 Reactome: R-HSA-1632852;Reactome: R-HSA-9613354;Reactome: R-HSA-5628897;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;Reactome: R-HSA-2151209;Reactome: R-HSA-200425;Reactome: R-HSA-163680;Reactome: R-HSA-380972;Reactome: R-HSA-1445148 "Macroautophagy";"Lipophagy";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Carnitine metabolism";"AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_037294235.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_030031336.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037299356.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037298095.1 3 Reactome: R-HSA-1660662;KEGG: 00600+3.2.1.45;KEGG: 00511+3.2.1.45 "Glycosphingolipid metabolism";"Sphingolipid metabolism";"Other glycan degradation" XP_030028608.2 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_037303012.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_030024075.2 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection" XP_030030378.2 18 Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-8051;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482801;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;KEGG: 00591+3.1.1.4 "Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Acyl chain remodelling of PG";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Acyl chain remodelling of PI";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PS";"Anandamide biosynthesis II";"Synthesis of PA";"Linoleic acid metabolism" XP_030025619.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030038801.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_030021589.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037295018.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030034906.1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9633012 "Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_037297722.1 4 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin" XP_030040379.1 8 Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-182218;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-167590;Reactome: R-HSA-983712;Reactome: R-HSA-9636467 "Transferrin endocytosis and recycling";"Insulin receptor recycling";"Nef Mediated CD8 Down-regulation";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Nef Mediated CD4 Down-regulation";"Ion channel transport";"Blockage of phagosome acidification" XP_037298043.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_030027163.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins" XP_037301995.1 27 Reactome: R-HSA-4615885;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-4551638 "SUMOylation of DNA replication proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins" XP_030029501.1 6 MetaCyc: PWY-1622;MetaCyc: PWY-5484;KEGG: 00260+5.4.2.11;MetaCyc: PWY-8004;KEGG: 00010+5.4.2.11;KEGG: 00680+5.4.2.11 "Formaldehyde assimilation I (serine pathway)";"Glycolysis II (from fructose 6-phosphate)";"Glycine, serine and threonine metabolism";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Methane metabolism" XP_030027903.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_030024869.2 16 Reactome: R-HSA-9018519;Reactome: R-HSA-3214847;Reactome: R-HSA-5693554;Reactome: R-HSA-5693548;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-201722;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-6804756 "Estrogen-dependent gene expression";"HATs acetylate histones";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Sensing of DNA Double Strand Breaks";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Formation of the beta-catenin:TCF transactivating complex";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Regulation of TP53 Activity through Phosphorylation" XP_030040944.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_030034529.1 3 Reactome: R-HSA-8964058;Reactome: R-HSA-9029569;Reactome: R-HSA-1369062 "HDL remodeling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"ABC transporters in lipid homeostasis" XP_037293234.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037299993.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_030023937.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037302091.1 4 Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism" XP_037298447.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_030029225.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_030034760.1 8 MetaCyc: PWY-7573;KEGG: 00520+4.2.1.47;MetaCyc: PWY-5738;KEGG: 00051+4.2.1.47;Reactome: R-HSA-6787639;MetaCyc: PWY-66;MetaCyc: PWY-5739;MetaCyc: PWY-5740 "GDP-mycosamine biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-6-deoxy-D-talose biosynthesis";"Fructose and mannose metabolism";"GDP-fucose biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-D-perosamine biosynthesis";"GDP-L-colitose biosynthesis" XP_030040195.2 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_037298643.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_030040317.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_037294982.1 5 Reactome: R-HSA-5221030;Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-110328;Reactome: R-HSA-110357 "TET1,2,3 and TDG demethylate DNA";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1" XP_030023072.1 4 Reactome: R-HSA-3371568;Reactome: R-HSA-9018519;Reactome: R-HSA-8939211;Reactome: R-HSA-3371497 "Attenuation phase";"Estrogen-dependent gene expression";"ESR-mediated signaling";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_030037356.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_030026899.1 10 Reactome: R-HSA-76042;Reactome: R-HSA-6807505;Reactome: R-HSA-9018519;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73779 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes";"Estrogen-dependent gene expression";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_037301593.1 14 Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-167242 "RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat" XP_030025244.2 2 Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_037295912.1 3 Reactome: R-HSA-381038;Reactome: R-HSA-8957275;Reactome: R-HSA-381426 "XBP1(S) activates chaperone genes";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_037303026.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_030025651.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037296577.1 4 MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807;Reactome: R-HSA-71737 "(aminomethyl)phosphonate degradation";"Oxidative phosphorylation";"Glyphosate degradation III";"Pyrophosphate hydrolysis" XP_030027081.2 5 KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.10;KEGG: 00230+2.7.4.3 "Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine metabolism" XP_037295919.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_030035814.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030019886.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037302884.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030030005.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_030030697.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030040544.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_030028468.1 5 KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22 "Galactose metabolism";"Sphingolipid metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism" XP_037301057.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037294088.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_030023851.2 6 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10;MetaCyc: PWY-5514;Reactome: R-HSA-446210;KEGG: 00520+5.4.2.3;MetaCyc: PWY-6906 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation" XP_030034556.1 7 Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-73980 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination" XP_030025254.2 2 Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_037292641.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037293302.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_037296583.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_037300987.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_030019832.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_030024730.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037295967.1 6 Reactome: R-HSA-912446;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-6796648;Reactome: R-HSA-5545483;Reactome: R-HSA-5632987 "Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MLH1";"Defective Mismatch Repair Associated With PMS2" XP_030028600.2 10 KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00330+1.2.1.41;KEGG: 00332+2.7.2.11;MetaCyc: PWY-6922;KEGG: 00332+1.2.1.41;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00330+2.7.2.11;Reactome: R-HSA-8964539 "Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"Glutamate and glutamine metabolism" XP_030032517.1 1 Reactome: R-HSA-419771 "Opsins" XP_037294537.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037294073.1 6 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-8939211;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221;Reactome: R-HSA-5693565 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"ESR-mediated signaling";"T cell receptor signaling pathway";"Negative regulation of MAPK pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_037295406.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_030021065.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030021647.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_037298120.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_037301962.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037302818.1 5 Reactome: R-HSA-6798695;MetaCyc: PWY-5188;MetaCyc: PWY-5189;Reactome: R-HSA-189451;KEGG: 00860+4.2.1.24 "Neutrophil degranulation";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism" XP_037303547.1 1 Reactome: R-HSA-2995383 "Initiation of Nuclear Envelope Reformation" XP_030019556.2 10 Reactome: R-HSA-9022699;Reactome: R-HSA-9022702;Reactome: R-HSA-9615017;Reactome: R-HSA-983231;Reactome: R-HSA-8936459;Reactome: R-HSA-9022538;Reactome: R-HSA-3899300;Reactome: R-HSA-427413;Reactome: R-HSA-9022692;Reactome: R-HSA-400206 "MECP2 regulates neuronal receptors and channels";"MECP2 regulates transcription of neuronal ligands";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Loss of MECP2 binding ability to 5mC-DNA";"SUMOylation of transcription cofactors";"NoRC negatively regulates rRNA expression";"Regulation of MECP2 expression and activity";"Regulation of lipid metabolism by PPARalpha" XP_037301875.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_037297578.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_030035579.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_030023327.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037296827.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_037297648.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_037300810.1 9 Reactome: R-HSA-9613829;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-9646399;Reactome: R-HSA-5627083;Reactome: R-HSA-5678895;Reactome: R-HSA-8856828;Reactome: R-HSA-9615710;Reactome: R-HSA-8856825 "Chaperone Mediated Autophagy";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"Aggrephagy";"RHO GTPases regulate CFTR trafficking";"Defective CFTR causes cystic fibrosis";"Clathrin-mediated endocytosis";"Late endosomal microautophagy";"Cargo recognition for clathrin-mediated endocytosis" XP_030027136.2 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037294079.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037295016.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_030023661.2 2 Reactome: R-HSA-1362409;Reactome: R-HSA-1268020 "Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import" XP_037293064.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_030021590.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037298405.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_030027125.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_030032667.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037292259.1 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection" XP_037300218.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030037492.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_030027265.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_030026596.1 5 Reactome: R-HSA-9630222;Reactome: R-HSA-9630221;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110357 "Defective NTHL1 substrate binding";"Defective NTHL1 substrate processing";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1" XP_030031630.2 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_037300100.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_037294143.1 8 Reactome: R-HSA-1483148;KEGG: 00564+3.1.3.27;MetaCyc: PWY-5668;MetaCyc: PWY-5269;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;MetaCyc: PWY-7817;KEGG: 04658+3.1.3.16 "Synthesis of PG";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis I";"Cardiolipin biosynthesis II";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Th1 and Th2 cell differentiation" XP_037293910.1 33 Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-141444;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-159230;Reactome: R-HSA-2500257;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-159231;Reactome: R-HSA-68877;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-168271 "SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"RHO GTPases Activate Formins";"Transport of the SLBP Dependant Mature mRNA";"Resolution of Sister Chromatid Cohesion";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Mitotic Prometaphase";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"Viral Messenger RNA Synthesis";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus" XP_030025818.1 6 Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-380994 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_030032444.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_030021042.1 8 Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-6782210;Reactome: R-HSA-8866652;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-8948747;Reactome: R-HSA-6782135 "Ub-specific processing proteases";"Regulation of TP53 Degradation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Regulation of PTEN localization";"Dual incision in TC-NER" XP_030034750.2 1 Reactome: R-HSA-70171 "Glycolysis" XP_030040921.1 6 MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;MetaCyc: PWY-5067;Reactome: R-HSA-189085;KEGG: 00500+3.2.1.1 "Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_030034373.2 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037292886.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_030026706.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_030030010.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_030026540.2 11 Reactome: R-HSA-168138;Reactome: R-HSA-1660517;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1660499;Reactome: R-HSA-5668599;Reactome: R-HSA-109704;MetaCyc: PWY-6352;Reactome: R-HSA-1632852 "Toll Like Receptor 9 (TLR9) Cascade";"Synthesis of PIPs at the late endosome membrane";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"RHO GTPases Activate NADPH Oxidases";"PI3K Cascade";"3-phosphoinositide biosynthesis";"Macroautophagy" XP_030024278.2 5 KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-6902 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)" XP_030028222.2 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_030022411.2 5 Reactome: R-HSA-209543;Reactome: R-HSA-5205685;Reactome: R-HSA-209560;Reactome: R-HSA-9020702;Reactome: R-HSA-205043 "p75NTR recruits signalling complexes";"Pink/Parkin Mediated Mitophagy";"NF-kB is activated and signals survival";"Interleukin-1 signaling";"NRIF signals cell death from the nucleus" XP_037294185.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes" XP_037300096.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_030026677.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037294599.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_030031611.2 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_037295745.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037292685.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037294002.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_030033788.2 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037294094.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_030033690.1 3 KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596 "Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I" XP_030028305.2 6 KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165;KEGG: 00930+3.1.1.17;MetaCyc: PWY-5530;MetaCyc: PWY-2221;KEGG: 00030+3.1.1.17 "Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)";"Caprolactam degradation";"Sorbitol biosynthesis II";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pentose phosphate pathway" XP_030022091.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_030041179.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037302037.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" XP_030022178.2 6 Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_037296280.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_037292320.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_030033260.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_030035250.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_037300791.1 7 Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-373753;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-264870;Reactome: R-HSA-6798695 "Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"Nephrin family interactions";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation" XP_030025773.1 5 Reactome: R-HSA-3270619;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-6798695 "IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"Neutrophil degranulation" XP_037293965.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_030027231.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_037302477.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_030026604.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037299707.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_037294384.1 9 KEGG: 00983+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-7533;KEGG: 00980+2.5.1.18;KEGG: 00480+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-6842 "Drug metabolism - other enzymes";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Metabolism of xenobiotics by cytochrome P450";"Glutathione metabolism";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II" XP_037295502.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_030020092.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402 "Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex" XP_037296263.1 26 Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-389977;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-389960;Reactome: R-HSA-8955332;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833 "Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Aggrephagy";"Post-chaperonin tubulin folding pathway";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Recycling pathway of L1";"Formation of tubulin folding intermediates by CCT/TriC";"Carboxyterminal post-translational modifications of tubulin";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Cilium Assembly" XP_030025105.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-1660662;Reactome: R-HSA-4085001;Reactome: R-HSA-4341670 "Neutrophil degranulation";"MHC class II antigen presentation";"Glycosphingolipid metabolism";"Sialic acid metabolism";"Defective NEU1 causes sialidosis" XP_037302438.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037299278.1 7 Reactome: R-HSA-6798695;MetaCyc: PWY-6724;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.25;Reactome: R-HSA-70221;MetaCyc: PWY-7238;MetaCyc: PWY-5941 "Neutrophil degranulation";"Starch degradation II";"Starch degradation V";"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II";"Glycogen degradation II" XP_030040623.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_037303481.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_030027250.1 16 MetaCyc: PWY-5723;MetaCyc: PWY-6886;MetaCyc: PWY-7124;MetaCyc: PWY-7218;Reactome: R-HSA-70171;KEGG: 00010+4.2.1.11;Reactome: R-HSA-70263;KEGG: 00680+4.2.1.11;MetaCyc: PWY-7003;MetaCyc: PWY-6901;MetaCyc: PWY-1622;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-8004;MetaCyc: PWY-2221 "Rubisco shunt";"1-butanol autotrophic biosynthesis (engineered)";"Ethylene biosynthesis V (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Methane metabolism";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Formaldehyde assimilation I (serine pathway)";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway I";"Entner-Doudoroff pathway III (semi-phosphorylative)" XP_030024657.1 5 Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-72163 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway" XP_037297636.1 3 Reactome: R-HSA-6809371;Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Formation of the cornified envelope";"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_037299424.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_030025204.1 3 MetaCyc: PWY-4041;KEGG: 00480+4.3.2.9;Reactome: R-HSA-174403 "Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione synthesis and recycling" XP_030020094.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_030037850.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030024687.2 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_030030429.1 13 KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822 "Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Keratan sulfate degradation";"CS/DS degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)" XP_037299915.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_030030646.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-964975;MetaCyc: PWY-7282;KEGG: 00750+2.7.1.35;MetaCyc: PWY-7204 "Neutrophil degranulation";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)" XP_030032564.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_037294179.1 7 Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2660826 "Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant" XP_037299487.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226 "Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_030036958.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037293021.1 3 Reactome: R-HSA-392517;Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Rap1 signalling";"Ca2+ pathway";"cGMP effects" XP_030029826.2 8 Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5689880;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912 "Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Ub-specific processing proteases";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane" XP_030019625.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_030040869.2 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_030025076.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_030027246.1 57 Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346 "Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Vpu mediated degradation of CD4";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"Hedgehog ligand biogenesis" XP_037302107.1 2 Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_037294012.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037295385.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_030040610.1 5 MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73621;Reactome: R-HSA-73614 "Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine catabolism";"Pyrimidine salvage" XP_030038544.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_037295121.1 1 Reactome: R-HSA-375276 "Peptide ligand-binding receptors" XP_037294924.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_037301052.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_030030799.2 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037292930.1 5 Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-2871796 "Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation" XP_030019634.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030032937.1 4 Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_030028979.2 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037300450.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6811434 "Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037298253.1 12 Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-447038;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;Reactome: R-HSA-451308;Reactome: R-HSA-399719;MetaCyc: PWY-7221;Reactome: R-HSA-438066;Reactome: R-HSA-5673001 "Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"NrCAM interactions";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"Activation of Ca-permeable Kainate Receptor";"Trafficking of AMPA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade" XP_037300809.1 9 Reactome: R-HSA-9613829;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-5627083;Reactome: R-HSA-9646399;Reactome: R-HSA-5678895;Reactome: R-HSA-8856828;Reactome: R-HSA-9615710;Reactome: R-HSA-8856825 "Chaperone Mediated Autophagy";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"RHO GTPases regulate CFTR trafficking";"Aggrephagy";"Defective CFTR causes cystic fibrosis";"Clathrin-mediated endocytosis";"Late endosomal microautophagy";"Cargo recognition for clathrin-mediated endocytosis" XP_030022795.1 3 Reactome: R-HSA-2022854;Reactome: R-HSA-5083627;Reactome: R-HSA-5173105 "Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation" XP_037300516.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037293133.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_030038385.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_037298517.1 10 KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11;MetaCyc: PWY-7385;MetaCyc: PWY-5484 "Methane metabolism";"Pentose phosphate pathway";"Galactose metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)" XP_030024793.2 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_030038009.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_030031442.2 14 MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7619 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis" XP_037293027.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_030022966.2 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_030038564.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_030031480.1 6 KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165;KEGG: 00030+3.1.1.17;MetaCyc: PWY-2221;KEGG: 00930+3.1.1.17;MetaCyc: PWY-5530 "Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)";"Pentose phosphate pathway";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Caprolactam degradation";"Sorbitol biosynthesis II" XP_030029166.2 3 MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-5358493 "Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2" XP_037292995.1 3 Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-110329 "Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine" XP_037292740.1 6 Reactome: R-HSA-139915;Reactome: R-HSA-6803205;Reactome: R-HSA-6804759;Reactome: R-HSA-6803207;Reactome: R-HSA-6803211;Reactome: R-HSA-6803204 "Activation of PUMA and translocation to mitochondria";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_037298081.1 6 Reactome: R-HSA-2173796;Reactome: R-HSA-201722;Reactome: R-HSA-8957275;Reactome: R-HSA-5626467;Reactome: R-HSA-381426;Reactome: R-HSA-3769402 "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of the beta-catenin:TCF transactivating complex";"Post-translational protein phosphorylation";"RHO GTPases activate IQGAPs";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Deactivation of the beta-catenin transactivating complex" XP_037297200.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518 "Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2" XP_030036761.1 9 Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852 "Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"MAP2K and MAPK activation";"Neutrophil degranulation";"mTOR signalling";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Macroautophagy" XP_030030803.2 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037303010.1 24 Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-8852276 "Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"Aggrephagy";"Recycling pathway of L1";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint" XP_037298048.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037297184.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_037298406.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_030037720.1 3 MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403 "5-oxo-L-proline metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling" XP_030030965.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037293926.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_037303342.1 8 Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-165054;Reactome: R-HSA-141444 "SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_030024296.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_030024726.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037299128.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035 "Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"(9Z)-tricosene biosynthesis" XP_037302178.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_030022262.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037299318.1 12 KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;MetaCyc: PWY-8053;MetaCyc: PWY-7417 "Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)" XP_037300082.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037292976.1 5 KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-7268 "Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_030035171.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_030032532.1 7 MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897;KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-210500;KEGG: 00250+3.5.1.2 "Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis";"TP53 Regulates Metabolic Genes";"D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"Glutamate Neurotransmitter Release Cycle";"Alanine, aspartate and glutamate metabolism" XP_037300414.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037297439.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2 "VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway" XP_037295518.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_030037267.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807 "Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism" XP_030027487.1 7 Reactome: R-HSA-8856828;KEGG: 04070+3.1.3.36;KEGG: 00562+3.1.3.36;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;Reactome: R-HSA-1855183;Reactome: R-HSA-1855204 "Clathrin-mediated endocytosis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol" XP_030020489.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_030037796.1 3 KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;MetaCyc: PWY-7807 "Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III" XP_037298829.1 3 MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism" XP_030021492.1 2 Reactome: R-HSA-446199;KEGG: 00510+3.6.1.43 "Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis" XP_030040728.1 24 Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295 "Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"Aggrephagy";"Recycling pathway of L1";"Mitotic Prometaphase";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"HCMV Early Events";"Cilium Assembly";"MHC class II antigen presentation" XP_037298315.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037302581.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_030026536.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_030041290.1 6 Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-416476 "Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events" XP_030038704.2 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_030028068.1 7 KEGG: 00220+3.5.3.1;MetaCyc: PWY-31;MetaCyc: PWY-6922;KEGG: 00330+3.5.3.1;MetaCyc: PWY-46;MetaCyc: PWY-4984;Reactome: R-HSA-70635 "Arginine biosynthesis";"Canavanine degradation";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Putrescine biosynthesis III";"Urea cycle";"Urea cycle" XP_030033061.2 5 Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_037303357.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030023294.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037296730.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_030020760.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_030038037.2 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037295008.1 13 MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52 "Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Other glycan degradation" XP_037300083.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030032986.1 3 Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14 "Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis" XP_030041141.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_030030619.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_030023799.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037302396.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037296672.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037299261.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-6790901 "Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol" XP_030025000.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_030029189.1 1 Reactome: R-HSA-2465910 "MASTL Facilitates Mitotic Progression" XP_030021022.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030040085.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_037302140.1 6 MetaCyc: PWY-5743;MetaCyc: PWY-6722;MetaCyc: PWY-4381;MetaCyc: PWY-5789;Reactome: R-HSA-196780;MetaCyc: PWY-5744 "3-hydroxypropanoate cycle";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"Glyoxylate assimilation" XP_030038470.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_030037613.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_030035430.1 4 KEGG: 00970+6.1.1.6;Reactome: R-HSA-2408522;Reactome: R-HSA-379716;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation" XP_037298966.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030031094.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037294551.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_030040082.2 24 Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-380320 "MHC class II antigen presentation";"Cilium Assembly";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Recycling pathway of L1";"Aggrephagy";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes" XP_037292942.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380284 "Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_030027919.1 26 Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-389977;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-389960;Reactome: R-HSA-437239;Reactome: R-HSA-9648025;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"HCMV Early Events";"Cilium Assembly";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"Post-chaperonin tubulin folding pathway";"Aggrephagy";"Mitotic Prometaphase";"Formation of tubulin folding intermediates by CCT/TriC";"Recycling pathway of L1";"EML4 and NUDC in mitotic spindle formation";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"COPI-mediated anterograde transport" XP_030036084.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030019667.2 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_037294335.1 10 MetaCyc: PWY-4041;MetaCyc: PWY-7112;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-7559;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-5826 "Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis" XP_030027940.1 11 MetaCyc: PWY-6606;KEGG: 00240+3.1.3.5;MetaCyc: PWY-6607;MetaCyc: PWY-7821;MetaCyc: PWY-7185;MetaCyc: PWY-5381;MetaCyc: PWY-5695;KEGG: 00760+3.1.3.5;KEGG: 00230+3.1.3.5;MetaCyc: PWY-6608;MetaCyc: PWY-6596 "Guanosine nucleotides degradation II";"Pyrimidine metabolism";"Guanosine nucleotides degradation I";"Tunicamycin biosynthesis";"UTP and CTP dephosphorylation I";"Pyridine nucleotide cycling (plants)";"Inosine 5'-phosphate degradation";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Guanosine nucleotides degradation III";"Adenosine nucleotides degradation I" XP_030025168.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_030020162.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037292358.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037300163.1 10 Reactome: R-HSA-8934903;Reactome: R-HSA-201688;Reactome: R-HSA-1483191;Reactome: R-HSA-6798695;Reactome: R-HSA-2514853;Reactome: R-HSA-445144;Reactome: R-HSA-6804756;Reactome: R-HSA-8939243;Reactome: R-HSA-8948751;Reactome: R-HSA-6814122 "Receptor Mediated Mitophagy";"WNT mediated activation of DVL";"Synthesis of PC";"Neutrophil degranulation";"Condensation of Prometaphase Chromosomes";"Signal transduction by L1";"Regulation of TP53 Activity through Phosphorylation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_037294122.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_030023726.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947 "Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription" XP_037295615.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037298902.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_030020762.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_037292327.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_030024179.2 4 Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport" XP_030030577.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030040408.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037293937.1 4 Reactome: R-HSA-9020702;MetaCyc: PWY-7511;Reactome: R-HSA-975144;Reactome: R-HSA-937039 "Interleukin-1 signaling";"Protein ubiquitination";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex" XP_037295415.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_037292367.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_030038234.1 57 Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-532668;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-983168;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-69601;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-5689603 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"UCH proteinases" XP_030037708.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_037303362.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037295616.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030037311.1 4 Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic" XP_030031439.2 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-6433 "Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)" XP_037293761.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030021630.1 3 Reactome: R-HSA-1660661;Reactome: R-HSA-6798695;Reactome: R-HSA-9609523 "Sphingolipid de novo biosynthesis";"Neutrophil degranulation";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_037296046.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-195253 "Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex" XP_030027763.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_030026676.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_037299119.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_030031773.1 7 MetaCyc: PWY-5469;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-6824 "Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Justicidin B biosynthesis" XP_030037987.1 16 Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72689 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits" XP_030029055.2 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_037298479.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-389397 "G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors" XP_030026313.2 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_037295015.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_030021420.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380284 "Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_037297960.1 2 Reactome: R-HSA-5601884;Reactome: R-HSA-1221632 "PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis" XP_030031116.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037303368.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_030034348.2 4 Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48 "Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Drug metabolism - other enzymes" XP_037296493.1 8 Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-68827 "Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex" XP_037299023.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_030019862.1 56 Reactome: R-HSA-8939902;Reactome: R-HSA-69601;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-174154;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974 "Regulation of RUNX2 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway" XP_030036081.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030021599.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037295703.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_030040228.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030020690.1 2 Reactome: R-HSA-6782315;Reactome: R-HSA-6787450 "tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion" XP_030031817.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037301954.1 2 MetaCyc: PWY-5697;KEGG: 00230+3.5.3.4 "Allantoin degradation to ureidoglycolate I (urea producing)";"Purine metabolism" XP_030028412.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_030040315.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_037294449.1 12 KEGG: 04150+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04926+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-5655302;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1839117;Reactome: R-HSA-194840;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"G alpha (12/13) signalling events";"Relaxin signaling pathway";"NRAGE signals death through JNK";"Signaling by FGFR1 in disease";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Signaling by cytosolic FGFR1 fusion mutants";"Rho GTPase cycle";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection" XP_030031466.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_030021540.2 11 KEGG: 04150+2.7.11.1;Reactome: R-HSA-9614657;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;Reactome: R-HSA-163680;Reactome: R-HSA-380972;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"FOXO-mediated transcription of cell death genes";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"Thermogenesis";"Human cytomegalovirus infection" XP_037299853.1 24 Reactome: R-HSA-418592;Reactome: R-HSA-163359;Reactome: R-HSA-392851;Reactome: R-HSA-392451;Reactome: R-HSA-9009391;Reactome: R-HSA-418555;Reactome: R-HSA-8964315;Reactome: R-HSA-392170;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-416482;Reactome: R-HSA-456926;Reactome: R-HSA-418217;Reactome: R-HSA-420092;Reactome: R-HSA-500657;Reactome: R-HSA-418597;Reactome: R-HSA-4086398;Reactome: R-HSA-381676;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-416476;Reactome: R-HSA-202040;Reactome: R-HSA-432040;Reactome: R-HSA-428930 "ADP signalling through P2Y purinoceptor 1";"Glucagon signaling in metabolic regulation";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through PI3Kgamma";"Extra-nuclear estrogen signaling";"G alpha (s) signalling events";"G beta:gamma signalling through BTK";"ADP signalling through P2Y purinoceptor 12";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through PLC beta";"Glucagon-type ligand receptors";"Presynaptic function of Kainate receptors";"G alpha (z) signalling events";"Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (q) signalling events";"G-protein activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thromboxane signalling through TP receptor" XP_030027474.1 6 Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-5620922 "Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium" XP_037302952.1 5 Reactome: R-HSA-427413;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-212300;Reactome: R-HSA-5334118 "NoRC negatively regulates rRNA expression";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"PRC2 methylates histones and DNA";"DNA methylation" XP_037297852.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-606279;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Deposition of new CENPA-containing nucleosomes at the centromere";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_037294727.1 13 Reactome: R-HSA-114508;Reactome: R-HSA-381676;Reactome: R-HSA-4086398;Reactome: R-HSA-112043;Reactome: R-HSA-2029485;Reactome: R-HSA-139853;Reactome: R-HSA-5607763;Reactome: R-HSA-5578775;Reactome: R-HSA-2871809;Reactome: R-HSA-1489509;Reactome: R-HSA-5218921;Reactome: R-HSA-422356;Reactome: R-HSA-983695 "Effects of PIP2 hydrolysis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway";"PLC beta mediated events";"Role of phospholipids in phagocytosis";"Elevation of cytosolic Ca2+ levels";"CLEC7A (Dectin-1) induces NFAT activation";"Ion homeostasis";"FCERI mediated Ca+2 mobilization";"DAG and IP3 signaling";"VEGFR2 mediated cell proliferation";"Regulation of insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers" XP_030029659.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037294596.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_030023718.1 10 MetaCyc: PWY-5497;MetaCyc: PWY-5030;MetaCyc: PWY-1722;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;MetaCyc: PWY-7909;MetaCyc: PWY-3841;MetaCyc: PWY-6613;KEGG: 00720+1.5.1.5+3.5.4.9 "Purine nucleobases degradation II (anaerobic)";"L-histidine degradation III";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Metabolism of folate and pterines";"One carbon pool by folate";"Folate transformations I";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Carbon fixation pathways in prokaryotes" XP_030021009.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030026886.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030034672.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_030020625.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9633012 "L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_030041005.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037302551.1 19 Reactome: R-HSA-9609736;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-6802955;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775 "Assembly and cell surface presentation of NMDA receptors";"Ion transport by P-type ATPases";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Long-term potentiation";"RAF/MAP kinase cascade";"Ion homeostasis" XP_030041135.2 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037296159.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030027331.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" XP_030022659.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_030032522.1 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_037293853.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_030040167.2 5 Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-4341670;Reactome: R-HSA-1660662;Reactome: R-HSA-4085001 "Neutrophil degranulation";"MHC class II antigen presentation";"Defective NEU1 causes sialidosis";"Glycosphingolipid metabolism";"Sialic acid metabolism" XP_037292760.1 5 Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-5675221;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955 "Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Negative regulation of MAPK pathway";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_037297156.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_030032987.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030033768.1 3 KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508;Reactome: R-HSA-418597 "Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"G alpha (z) signalling events" XP_030040412.2 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_030032188.1 2 Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation" XP_037292938.1 8 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-9636467;Reactome: R-HSA-167590;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-182218 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"Blockage of phagosome acidification";"Nef Mediated CD4 Down-regulation";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Nef Mediated CD8 Down-regulation" XP_030023638.2 12 Reactome: R-HSA-2142789;MetaCyc: PWY-5870;MetaCyc: PWY-5855;MetaCyc: PWY-5857;MetaCyc: PWY-7233;MetaCyc: PWY-7230;MetaCyc: PWY-5873;MetaCyc: PWY-5871;MetaCyc: PWY-5872;MetaCyc: PWY-5856;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-6708 "Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)" XP_030025210.2 1 KEGG: 00051+4.2.1.68 "Fructose and mannose metabolism" XP_037301473.1 15 Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569 "Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_030030239.1 6 MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1268020;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "ATP biosynthesis";"Oxidative phosphorylation";"Mitochondrial protein import";"Photosynthesis";"Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_030039906.2 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_030029052.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_030039411.1 2 Reactome: R-HSA-8869496;Reactome: R-HSA-6790901 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol" XP_037294498.1 1 Reactome: R-HSA-5578775 "Ion homeostasis" XP_030020761.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_030027243.1 7 KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis" XP_037298712.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_030036340.2 6 Reactome: R-HSA-6804759;Reactome: R-HSA-139915;Reactome: R-HSA-6803205;Reactome: R-HSA-6803204;Reactome: R-HSA-6803211;Reactome: R-HSA-6803207 "Regulation of TP53 Activity through Association with Co-factors";"Activation of PUMA and translocation to mitochondria";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Caspase Activators and Caspases" XP_037293340.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_037295380.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_037294377.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_030027219.2 2 MetaCyc: PWY-7511;Reactome: R-HSA-3108214 "Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins" XP_030032301.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-606279 "Fanconi Anemia Pathway";"Deposition of new CENPA-containing nucleosomes at the centromere" XP_030028791.1 3 KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8964208 "Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism" XP_037295599.1 3 KEGG: 00534+5.1.3.17;Reactome: R-HSA-2022928;MetaCyc: PWY-6558 "Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)" XP_030033165.1 17 KEGG: 00230+2.4.2.1;MetaCyc: PWY-6620;KEGG: 00760+2.4.2.1;Reactome: R-HSA-74259;Reactome: R-HSA-74217;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;MetaCyc: PWY-6609;MetaCyc: PWY-7179-1;MetaCyc: PWY-4202;KEGG: 00240+2.4.2.1;MetaCyc: PWY-5532;MetaCyc: PWY-6644;MetaCyc: PWY-7179;MetaCyc: PWY-6627;MetaCyc: PWY-5695;MetaCyc: PWY-6608 "Purine metabolism";"Guanine and guanosine salvage";"Nicotinate and nicotinamide metabolism";"Purine catabolism";"Purine salvage";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II";"Arsenate detoxification I (mammalian)";"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Fluoroacetate and fluorothreonine biosynthesis";"Purine deoxyribonucleosides degradation I";"Salinosporamide A biosynthesis";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation III" XP_030020816.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037299700.1 3 MetaCyc: PWY-5669;Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65 "Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE";"Glycerophospholipid metabolism" XP_037297500.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037300711.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_030025771.2 3 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_037295362.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_037301378.1 13 Reactome: R-HSA-5607763;Reactome: R-HSA-2871809;Reactome: R-HSA-5578775;Reactome: R-HSA-4086398;Reactome: R-HSA-381676;Reactome: R-HSA-114508;Reactome: R-HSA-139853;Reactome: R-HSA-2029485;Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-422356;Reactome: R-HSA-5218921;Reactome: R-HSA-1489509 "CLEC7A (Dectin-1) induces NFAT activation";"FCERI mediated Ca+2 mobilization";"Ion homeostasis";"Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Effects of PIP2 hydrolysis";"Elevation of cytosolic Ca2+ levels";"Role of phospholipids in phagocytosis";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Regulation of insulin secretion";"VEGFR2 mediated cell proliferation";"DAG and IP3 signaling" XP_037295878.1 6 MetaCyc: PWY-6364;KEGG: 04070+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6363;MetaCyc: PWY-6362;KEGG: 00562+3.1.3.56 "D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism" XP_037300101.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_030033359.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037293479.1 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection" XP_030040308.2 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_030035611.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037302171.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_037294128.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_030029998.1 11 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-171007;Reactome: R-HSA-450302;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"VEGFA-VEGFR2 Pathway";"p38MAPK events";"activated TAK1 mediates p38 MAPK activation";"Relaxin signaling pathway";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_037303348.1 2 Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism" XP_030035667.2 3 KEGG: 00534+5.1.3.17;MetaCyc: PWY-6558;Reactome: R-HSA-2022928 "Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis" XP_037294692.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_037292451.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_030023968.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" XP_030040714.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_030041033.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_030031118.2 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_030031899.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-5250924 "RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression" XP_030032898.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037299470.1 5 KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661 "Lysine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation" XP_037293630.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_030029187.1 25 Reactome: R-HSA-8955332;Reactome: R-HSA-380270;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399 "Carboxyterminal post-translational modifications of tubulin";"Recruitment of mitotic centrosome proteins and complexes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"MHC class II antigen presentation";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"Recycling pathway of L1";"Mitotic Prometaphase";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy" XP_030040144.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037300291.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_030036197.2 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_030035003.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-9020702 "Neutrophil degranulation";"Interleukin-1 signaling" XP_030026078.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_030040849.1 6 Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_030020071.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis" XP_037294139.1 33 Reactome: R-HSA-141444;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-68877;Reactome: R-HSA-159231;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-9648025;Reactome: R-HSA-168325;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"Mitotic Prometaphase";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"EML4 and NUDC in mitotic spindle formation";"Viral Messenger RNA Synthesis";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Separation of Sister Chromatids" XP_037303043.1 24 Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-9648025;Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-1445148 "Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"Aggrephagy";"Mitotic Prometaphase";"Recycling pathway of L1";"EML4 and NUDC in mitotic spindle formation";"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"HCMV Early Events";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_030024085.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_030035543.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_030028399.1 10 Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-6807505 "RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes" XP_037297532.1 6 MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism" XP_037297304.1 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" XP_037298819.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_037294120.1 7 KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.15;Reactome: R-HSA-379716;Reactome: R-HSA-6782315;MetaCyc: PWY-5188;Reactome: R-HSA-2408522 "Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"tRNA modification in the nucleus and cytosol";"Tetrapyrrole biosynthesis I (from glutamate)";"Selenoamino acid metabolism" YP_001650760.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_037296646.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism" XP_030036534.1 15 Reactome: R-HSA-5693548;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5693571;Reactome: R-HSA-5685939;Reactome: R-HSA-912446;Reactome: R-HSA-5693565;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-5693554 "Sensing of DNA Double Strand Breaks";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Nonhomologous End-Joining (NHEJ)";"HDR through MMEJ (alt-NHEJ)";"Meiotic recombination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_037300217.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037301241.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037293724.1 8 Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-165159 "TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"HSF1-dependent transactivation";"mTORC1-mediated signalling";"mTOR signalling" XP_037301221.1 15 Reactome: R-HSA-8948700;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway" XP_030031041.2 2 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Synthesis of PG";"Synthesis of PA" XP_037300335.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_030032292.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300 "SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors" XP_030036605.1 12 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-73772;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-73780;Reactome: R-HSA-5250924;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Chain Elongation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_030040319.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_037296186.1 5 KEGG: 00760+2.7.7.18;Reactome: R-HSA-196807;MetaCyc: PWY-5653;MetaCyc: PWY-5381;MetaCyc: PWY-7761 "Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)" XP_037295292.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_030028221.2 13 MetaCyc: PWY-5392;KEGG: 00020+4.2.1.2;KEGG: 00720+4.2.1.2;MetaCyc: PWY-6728;Reactome: R-HSA-71403;KEGG: 00620+4.2.1.2;MetaCyc: PWY-7254;MetaCyc: PWY-5913;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-7384;MetaCyc: PWY-561;MetaCyc: PWY-8086 "Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Pyruvate metabolism";"TCA cycle VII (acetate-producers)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Superpathway of glyoxylate cycle and fatty acid degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen" XP_037300574.1 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" XP_030034186.2 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_030028069.1 7 KEGG: 00330+3.5.3.1;KEGG: 00220+3.5.3.1;MetaCyc: PWY-31;MetaCyc: PWY-6922;Reactome: R-HSA-70635;MetaCyc: PWY-46;MetaCyc: PWY-4984 "Arginine and proline metabolism";"Arginine biosynthesis";"Canavanine degradation";"L-Ndelta-acetylornithine biosynthesis";"Urea cycle";"Putrescine biosynthesis III";"Urea cycle" XP_030028569.1 30 Reactome: R-HSA-6804758;Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1;Reactome: R-HSA-8876198;Reactome: R-HSA-392451;Reactome: R-HSA-389513;Reactome: R-HSA-111447;Reactome: R-HSA-9634638;Reactome: R-HSA-69656;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804759;Reactome: R-HSA-5218920;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;Reactome: R-HSA-69202;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-6804757;Reactome: R-HSA-198693;Reactome: R-HSA-8941332;Reactome: R-HSA-9614399;Reactome: R-HSA-1358803;Reactome: R-HSA-8948751;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-199418;KEGG: 05165+2.7.11.1;Reactome: R-HSA-211163;Reactome: R-HSA-389357 "Regulation of TP53 Activity through Acetylation";"Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection";"RAB GEFs exchange GTP for GDP on RABs";"G beta:gamma signalling through PI3Kgamma";"CTLA4 inhibitory signaling";"Activation of BAD and translocation to mitochondria";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Cyclin A:Cdk2-associated events at S phase entry";"Human cytomegalovirus infection";"Thermogenesis";"Regulation of TP53 Activity through Association with Co-factors";"VEGFR2 mediated vascular permeability";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"Cyclin E associated events during G1/S transition";"PI3K-Akt signaling pathway";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Degradation";"AKT phosphorylates targets in the nucleus";"RUNX2 regulates genes involved in cell migration";"Regulation of localization of FOXO transcription factors";"Downregulation of ERBB2:ERBB3 signaling";"Regulation of PTEN stability and activity";"mTOR signaling pathway";"PIP3 activates AKT signaling";"Negative regulation of the PI3K/AKT network";"Human papillomavirus infection";"AKT-mediated inactivation of FOXO1A";"CD28 dependent PI3K/Akt signaling" XP_030026594.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_030031667.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_030025752.2 5 Reactome: R-HSA-6798695;Reactome: R-HSA-3249367;Reactome: R-HSA-3134975;Reactome: R-HSA-1834941;Reactome: R-HSA-3270619 "Neutrophil degranulation";"STAT6-mediated induction of chemokines";"Regulation of innate immune responses to cytosolic DNA";"STING mediated induction of host immune responses";"IRF3-mediated induction of type I IFN" XP_037300763.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_030031776.1 7 MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-5461 "Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation" XP_037293305.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_030032673.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_037293233.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030029623.2 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6785470 "tRNA processing in the nucleus";"tRNA processing in the mitochondrion" XP_030026273.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030035246.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_030023717.1 10 MetaCyc: PWY-7909;MetaCyc: PWY-3841;MetaCyc: PWY-6613;KEGG: 00720+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5497;MetaCyc: PWY-5030;MetaCyc: PWY-1722;MetaCyc: PWY-2201 "Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"L-histidine degradation III";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations I" XP_030021211.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_037299472.1 5 Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2 "Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation" XP_030025803.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030035256.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_037296572.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_030028224.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_030024708.2 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_037298116.1 2 Reactome: R-HSA-6811436;Reactome: R-HSA-8876198 "COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_030033175.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_030036199.2 9 KEGG: 00360+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00401+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00960+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00130+2.6.1.5 "Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Cysteine and methionine metabolism";"Novobiocin biosynthesis";"Tyrosine catabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_030026069.2 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_030040526.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_037294962.1 7 Reactome: R-HSA-3000178;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;Reactome: R-HSA-9010553;Reactome: R-HSA-3000171;Reactome: R-HSA-5083629;Reactome: R-HSA-5083628 "ECM proteoglycans";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Regulation of expression of SLITs and ROBOs";"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3" XP_037294044.1 9 Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-6782135;Reactome: R-HSA-8951664;Reactome: R-HSA-6782210;Reactome: R-HSA-110314 "Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Dual incision in TC-NER";"Neddylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex" XP_030040166.2 5 Reactome: R-HSA-1660662;Reactome: R-HSA-4085001;Reactome: R-HSA-4341670;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695 "Glycosphingolipid metabolism";"Sialic acid metabolism";"Defective NEU1 causes sialidosis";"MHC class II antigen presentation";"Neutrophil degranulation" XP_037301070.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_037294115.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_030022486.2 3 Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;Reactome: R-HSA-5696394 "UCH proteinases";"HATs acetylate histones";"DNA Damage Recognition in GG-NER" XP_037296157.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037294533.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_030024765.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037302779.1 10 MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-8053;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-8055 "CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis" XP_030028643.2 2 Reactome: R-HSA-1482798;Reactome: R-HSA-1268020 "Acyl chain remodeling of CL";"Mitochondrial protein import" XP_037296795.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_030035429.1 4 Reactome: R-HSA-379726;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716 "Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_030040029.1 7 Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-6783310;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693616 "Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Fanconi Anemia Pathway";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_037297911.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_030028400.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_030025166.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_037296831.1 11 Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167200 "Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_037297286.1 3 MetaCyc: PWY-7888;Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_037294462.1 13 Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6802946;Reactome: R-HSA-6802948;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6802952;Reactome: R-HSA-5674135 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Signaling by moderate kinase activity BRAF mutants";"Signaling by high-kinase activity BRAF mutants";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation" XP_030021585.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030031134.2 1 Reactome: R-HSA-8951664 "Neddylation" XP_037295898.1 1 Reactome: R-HSA-390696 "Adrenoceptors" XP_037294852.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_037295674.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_037293459.1 7 KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection" XP_037293369.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins" XP_030037349.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037301002.1 5 Reactome: R-HSA-189085;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855 "Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)" XP_030026491.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_030036087.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037298804.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_030027823.1 23 Reactome: R-HSA-418597;Reactome: R-HSA-420092;Reactome: R-HSA-500657;Reactome: R-HSA-400042;Reactome: R-HSA-381676;Reactome: R-HSA-4086398;Reactome: R-HSA-8964616;Reactome: R-HSA-432040;Reactome: R-HSA-416476;Reactome: R-HSA-202040;Reactome: R-HSA-428930;Reactome: R-HSA-392851;Reactome: R-HSA-418592;Reactome: R-HSA-9009391;Reactome: R-HSA-418555;Reactome: R-HSA-8964315;Reactome: R-HSA-392451;Reactome: R-HSA-456926;Reactome: R-HSA-418217;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-416482;Reactome: R-HSA-392170 "G alpha (z) signalling events";"Glucagon-type ligand receptors";"Presynaptic function of Kainate receptors";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway";"G beta:gamma signalling through CDC42";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (q) signalling events";"G-protein activation";"Thromboxane signalling through TP receptor";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 1";"Extra-nuclear estrogen signaling";"G alpha (s) signalling events";"G beta:gamma signalling through BTK";"G beta:gamma signalling through PI3Kgamma";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through PLC beta";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (12/13) signalling events";"ADP signalling through P2Y purinoceptor 12" XP_037296882.1 5 Reactome: R-HSA-5685939;Reactome: R-HSA-6782210;Reactome: R-HSA-110381;Reactome: R-HSA-5649702;Reactome: R-HSA-5696397 "HDR through MMEJ (alt-NHEJ)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Resolution of AP sites via the single-nucleotide replacement pathway";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Gap-filling DNA repair synthesis and ligation in GG-NER" XP_030022166.1 3 Reactome: R-HSA-8875656;Reactome: R-HSA-8856828;Reactome: R-HSA-8854214 "MET receptor recycling";"Clathrin-mediated endocytosis";"TBC/RABGAPs" XP_037292270.1 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection" XP_030035691.2 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_030020778.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037296145.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037297602.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037293394.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_037301621.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_037301152.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_030037159.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030024443.2 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation" XP_037297328.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037295690.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_030032671.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_037298707.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037296000.1 14 Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167200 "RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_030032436.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037300439.1 32 Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-72203;Reactome: R-HSA-77075;Reactome: R-HSA-9018519;Reactome: R-HSA-167243;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-72163;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-72165;Reactome: R-HSA-167287;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-168325;Reactome: R-HSA-167152;Reactome: R-HSA-6803529;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-72086 "Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Pol II CTD phosphorylation and interaction with CE";"Estrogen-dependent gene expression";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Major Pathway";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Minor Pathway";"HIV elongation arrest and recovery";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"Viral Messenger RNA Synthesis";"Formation of HIV elongation complex in the absence of HIV Tat";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Capping" XP_030020637.2 4 Reactome: R-HSA-1655829;Reactome: R-HSA-381033;Reactome: R-HSA-8874211;Reactome: R-HSA-8963889 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones";"CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes" XP_030027158.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_030019638.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_030020948.2 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_037297605.1 14 Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-110312 "HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Translesion synthesis by POLK";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"Translesion synthesis by REV1" XP_037296978.1 2 Reactome: R-HSA-190373;Reactome: R-HSA-5654726 "FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling" XP_030035033.1 2 KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_030020994.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037293338.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_030039301.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037303255.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_037302370.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037293421.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_030030627.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_030028849.1 17 KEGG: 00640+6.4.1.2;MetaCyc: PWY-4381;Reactome: R-HSA-163765;Reactome: R-HSA-196780;MetaCyc: PWY-5744;MetaCyc: PWY-5966-1;KEGG: 00254+6.4.1.2;MetaCyc: PWY-6722;MetaCyc: PWY-6679;Reactome: R-HSA-3371599;KEGG: 00061+6.4.1.2;Reactome: R-HSA-2426168;MetaCyc: PWY-5789;KEGG: 00720+6.4.1.2;Reactome: R-HSA-200425;MetaCyc: PWY-5743;KEGG: 00620+6.4.1.2 "Propanoate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"ChREBP activates metabolic gene expression";"Biotin transport and metabolism";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Aflatoxin biosynthesis";"Candicidin biosynthesis";"Jadomycin biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Carbon fixation pathways in prokaryotes";"Carnitine metabolism";"3-hydroxypropanoate cycle";"Pyruvate metabolism" XP_030025929.1 12 MetaCyc: PWY-7238;MetaCyc: PWY-3801;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7343;Reactome: R-HSA-173599;KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9;MetaCyc: PWY-6527;KEGG: 00052+2.7.7.9;Reactome: R-HSA-3322077;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7817 "Sucrose biosynthesis II";"Sucrose degradation II (sucrose synthase)";"Starch and sucrose metabolism";"UDP-alpha-D-glucose biosynthesis I";"Formation of the active cofactor, UDP-glucuronate";"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Stachyose degradation";"Galactose metabolism";"Glycogen synthesis";"Amino sugar and nucleotide sugar metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_037292318.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_030020539.1 4 Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17;KEGG: 00790+4.1.99.22 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Folate biosynthesis" XP_030022346.2 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_037300170.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030020556.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_030032666.2 7 KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-7214 "Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)" XP_037300273.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_037293019.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_037302937.1 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_030030925.2 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_030040328.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_030022041.2 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_037292422.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_030022782.1 6 Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-6798695;Reactome: R-HSA-77387 "Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Neutrophil degranulation";"Insulin receptor recycling" XP_030026168.1 3 Reactome: R-HSA-948021;Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Transport to the Golgi and subsequent modification";"Cargo concentration in the ER";"COPII-mediated vesicle transport" XP_030022880.1 16 Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823 "Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation" XP_030021752.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030040691.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030023357.2 4 Reactome: R-HSA-4551295;KEGG: 00513+2.4.1.131;KEGG: 00510+2.4.1.131;Reactome: R-HSA-446193 "Defective ALG11 causes ALG11-CDG (CDG-1p)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_030032068.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037296834.1 27 Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-168276;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-4085377 "Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"snRNP Assembly";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"NS1 Mediated Effects on Host Pathways";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"SUMOylation of SUMOylation proteins" XP_030028848.1 17 MetaCyc: PWY-6679;KEGG: 00061+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-5966-1;KEGG: 00254+6.4.1.2;MetaCyc: PWY-6722;Reactome: R-HSA-196780;MetaCyc: PWY-5744;KEGG: 00640+6.4.1.2;MetaCyc: PWY-4381;Reactome: R-HSA-163765;KEGG: 00620+6.4.1.2;Reactome: R-HSA-200425;MetaCyc: PWY-5743;MetaCyc: PWY-5789;KEGG: 00720+6.4.1.2;Reactome: R-HSA-2426168 "Jadomycin biosynthesis";"Fatty acid biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Aflatoxin biosynthesis";"Candicidin biosynthesis";"Biotin transport and metabolism";"Glyoxylate assimilation";"Propanoate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"ChREBP activates metabolic gene expression";"Pyruvate metabolism";"Carnitine metabolism";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Carbon fixation pathways in prokaryotes";"Activation of gene expression by SREBF (SREBP)" XP_037293012.1 3 MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2 "ATP biosynthesis";"Photosynthesis";"Oxidative phosphorylation" XP_037299830.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037300575.1 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" XP_030034193.2 2 KEGG: 00230+1.7.1.7;Reactome: R-HSA-74217 "Purine metabolism";"Purine salvage" XP_030021366.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030034305.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_037293408.1 7 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection" XP_037297932.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037301266.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037293155.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_030021460.1 11 Reactome: R-HSA-418594;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-418555 "G alpha (i) signalling events";"PKA activation";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Hedgehog 'off' state";"G alpha (s) signalling events" XP_030040200.2 1 KEGG: 00970+6.1.1.20 "Aminoacyl-tRNA biosynthesis" XP_030024130.2 1 Reactome: R-HSA-5683826 "Surfactant metabolism" XP_037299870.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_030035119.2 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_030024981.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Minor Pathway" XP_037294602.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_030025530.1 3 Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-5362798 "Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Release of Hh-Np from the secreting cell" XP_030029157.2 4 Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664 "Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation" XP_030029266.2 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_037301164.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037302185.1 3 Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161 "Metabolism of folate and pterines";"Folate biosynthesis";"Folate polyglutamylation" XP_037298061.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_037297332.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037294470.1 2 MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24 "Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis" XP_037297146.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037298721.1 20 MetaCyc: PWY-7288;MetaCyc: PWY-735;MetaCyc: PWY-7291;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-5136;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7574;KEGG: 00592+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7726;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7340;MetaCyc: PWY-7007;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7338;MetaCyc: PWY-7858;MetaCyc: PWY-7854 "Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoate metabolism";"Propanoyl-coa degradation II";"alpha-Linolenic acid metabolism";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"6-gingerol analog biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)" XP_030023452.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030038319.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_030035211.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012 "Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_030034622.1 6 Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-176974 "Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Unwinding of DNA" XP_030028083.2 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_030026745.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037298661.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_037296983.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030021600.2 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" XP_030024626.1 22 Reactome: R-HSA-5358747;Reactome: R-HSA-5358752;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-196299;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5467348;Reactome: R-HSA-195253;Reactome: R-HSA-6811558;Reactome: R-HSA-4641262;Reactome: R-HSA-5675221;Reactome: R-HSA-389513;Reactome: R-HSA-5663220;Reactome: R-HSA-5467340;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-2500257 "S33 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"RAF activation";"APC truncation mutants have impaired AXIN binding";"Beta-catenin phosphorylation cascade";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Truncations of AMER1 destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Negative regulation of MAPK pathway";"CTLA4 inhibitory signaling";"RHO GTPases Activate Formins";"AXIN missense mutants destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion" XP_030035653.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_030020923.1 15 MetaCyc: PWY-7003;MetaCyc: PWY-8004;KEGG: 00620+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-7383;MetaCyc: PWY-7218;KEGG: 00230+2.7.1.40;MetaCyc: PWY-5723;MetaCyc: PWY-6886;MetaCyc: PWY-1042;Reactome: R-HSA-70171 "Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Pyruvate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Purine metabolism";"Rubisco shunt";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis" XP_037292775.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" XP_030035082.1 12 MetaCyc: PWY-6978;MetaCyc: PWY-6708;MetaCyc: PWY-5856;MetaCyc: PWY-5872;Reactome: R-HSA-1268020;MetaCyc: PWY-5873;MetaCyc: PWY-5871;Reactome: R-HSA-2142789;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5870;MetaCyc: PWY-5857;MetaCyc: PWY-5855 "Plastoquinol-9 biosynthesis II";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Mitochondrial protein import";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)" XP_030040204.2 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_030035608.2 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_030025288.1 9 Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724 "mTOR signalling";"mTORC1-mediated signalling";"Neutrophil degranulation";"MAP2K and MAPK activation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription" XP_037293960.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037299140.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_037294844.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_030034326.2 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_037303364.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_030019970.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_030027707.2 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_030030781.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_030023369.1 5 MetaCyc: PWY-5514;Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906;MetaCyc: PWY-6855 "UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Chitin degradation I (archaea)" XP_037298481.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_030021446.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_037303009.1 24 Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-9648025;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332 "Aggrephagy";"Mitotic Prometaphase";"Recycling pathway of L1";"EML4 and NUDC in mitotic spindle formation";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin" XP_030041146.2 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037301364.1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_030020254.2 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_030035161.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_030032497.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_030040539.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_037302200.1 4 Reactome: R-HSA-176974;Reactome: R-HSA-69205;Reactome: R-HSA-176187;Reactome: R-HSA-68962 "Unwinding of DNA";"G1/S-Specific Transcription";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex" XP_037292916.1 5 Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026 "Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)" XP_030028601.2 10 KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00332+1.2.1.41;MetaCyc: PWY-6922;KEGG: 00330+1.2.1.41+2.7.2.11;Reactome: R-HSA-8964539;KEGG: 00330+2.7.2.11;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00330+1.2.1.41;KEGG: 00332+2.7.2.11 "Carbapenem biosynthesis";"Carbapenem biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis" XP_030037507.1 18 MetaCyc: PWY-7221;MetaCyc: PWY-7198;MetaCyc: PWY-6545;MetaCyc: PWY-7184;MetaCyc: PWY-7220;MetaCyc: PWY-7226;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7187;Reactome: R-HSA-499943;MetaCyc: PWY-7205;MetaCyc: PWY-7222;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7197;MetaCyc: PWY-7224;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7210 "Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"CMP phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" XP_030026605.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" XP_037300840.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037292793.1 31 Reactome: R-HSA-199220;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5366;MetaCyc: PWY-7663;MetaCyc: PWY-5147;MetaCyc: PWY-5971;MetaCyc: PWY-5994;MetaCyc: PWY-7388;MetaCyc: PWY-5142;MetaCyc: PWY-5989;MetaCyc: PWY-5973;MetaCyc: PWY-7858;Reactome: R-HSA-75105;MetaCyc: PWYG-321;Reactome: R-HSA-2426168;MetaCyc: PWY-8012;MetaCyc: PWY-8047;MetaCyc: PWY-7746;MetaCyc: PWY-6113;MetaCyc: PWY-5966-1;MetaCyc: PWY-8049;MetaCyc: PWY-7723;Reactome: R-HSA-9029558;MetaCyc: PWY-7664;MetaCyc: PWY-4381;MetaCyc: PWY-6799;Reactome: R-HSA-163765;MetaCyc: PWY-6519;MetaCyc: PWY-6282;MetaCyc: PWY-5367;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41 "Vitamin B5 (pantothenate) metabolism";"Fatty acid biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Gondoate biosynthesis (anaerobic)";"Oleate biosynthesis I (plants)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Stearate biosynthesis II (bacteria and plants)";"Cis-vaccenate biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Fatty acyl-CoA biosynthesis";"";"Activation of gene expression by SREBF (SREBP)";"Mupirocin biosynthesis";"Bryostatin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Superpathway of mycolate biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Pederin biosynthesis";"Bacterial bioluminescence";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"ChREBP activates metabolic gene expression";"8-amino-7-oxononanoate biosynthesis I";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Petroselinate biosynthesis";"Biotin metabolism" XP_037302220.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_030022362.2 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_037295582.1 10 KEGG: 04150+2.7.1.153;MetaCyc: PWY-6352;Reactome: R-HSA-9027276;KEGG: 05163+2.7.1.153;KEGG: 04070+2.7.1.153;KEGG: 05165+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 04151+2.7.1.153;KEGG: 00562+2.7.1.153;KEGG: 05170+2.7.1.153 "mTOR signaling pathway";"3-phosphoinositide biosynthesis";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human cytomegalovirus infection";"Phosphatidylinositol signaling system";"Human papillomavirus infection";"Synthesis of PIPs at the plasma membrane";"PI3K-Akt signaling pathway";"Inositol phosphate metabolism";"Human immunodeficiency virus 1 infection" XP_030032999.2 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_037298758.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_030029583.2 6 Reactome: R-HSA-196819;MetaCyc: PWY-6898;MetaCyc: PWY-6907;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6908;MetaCyc: PWY-7356 "Vitamin B1 (thiamin) metabolism";"Thiamine salvage III";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine metabolism";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine salvage IV (yeast)" XP_037292516.1 5 Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-3928665 "Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"EPH-ephrin mediated repulsion of cells" XP_030036516.1 56 Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-1234176;Reactome: R-HSA-8939236;Reactome: R-HSA-8939902;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-180585 "Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX2 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G" XP_037301254.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_030040983.2 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_037295579.1 10 MetaCyc: PWY-6352;KEGG: 04150+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 05163+2.7.1.153;KEGG: 04070+2.7.1.153;KEGG: 05165+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 04151+2.7.1.153;KEGG: 00562+2.7.1.153;KEGG: 05170+2.7.1.153 "3-phosphoinositide biosynthesis";"mTOR signaling pathway";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human cytomegalovirus infection";"Phosphatidylinositol signaling system";"Human papillomavirus infection";"Synthesis of PIPs at the plasma membrane";"PI3K-Akt signaling pathway";"Inositol phosphate metabolism";"Human immunodeficiency virus 1 infection" XP_030034035.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_030029772.1 12 Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-1251985;Reactome: R-HSA-205043;Reactome: R-HSA-2122948;Reactome: R-HSA-193692;Reactome: R-HSA-2979096;Reactome: R-HSA-3928665;Reactome: R-HSA-2644606;Reactome: R-HSA-9013700;Reactome: R-HSA-977225;Reactome: R-HSA-9017802 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"Noncanonical activation of NOTCH3" XP_030022680.1 4 Reactome: R-HSA-73817;KEGG: 00230+6.3.5.2;MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2 "Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes" XP_037294312.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_037292874.1 31 MetaCyc: PWY-6282;MetaCyc: PWY-5367;MetaCyc: PWY-6799;MetaCyc: PWY-7664;Reactome: R-HSA-163765;MetaCyc: PWY-4381;MetaCyc: PWY-6519;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8049;MetaCyc: PWY-7723;Reactome: R-HSA-9029558;MetaCyc: PWY-7746;MetaCyc: PWY-5966-1;MetaCyc: PWY-6113;MetaCyc: PWY-8012;MetaCyc: PWY-8047;MetaCyc: PWYG-321;Reactome: R-HSA-2426168;MetaCyc: PWY-5142;MetaCyc: PWY-5973;MetaCyc: PWY-5989;MetaCyc: PWY-7858;Reactome: R-HSA-75105;MetaCyc: PWY-5994;MetaCyc: PWY-5971;MetaCyc: PWY-7388;MetaCyc: PWY-5366;MetaCyc: PWY-7663;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-199220;MetaCyc: PWY-5147 "Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Petroselinate biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Oleate biosynthesis IV (anaerobic)";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"Biotin metabolism";"Pederin biosynthesis";"Bacterial bioluminescence";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Superpathway of mycolate biosynthesis";"Mupirocin biosynthesis";"Bryostatin biosynthesis";"";"Activation of gene expression by SREBF (SREBP)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Cis-vaccenate biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"(5Z)-dodecenoate biosynthesis II";"Fatty acyl-CoA biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitoleate biosynthesis II (plants and bacteria)";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Oleate biosynthesis I (plants)" XP_030029382.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037292644.1 6 Reactome: R-HSA-2426168;MetaCyc: PWY-922;KEGG: 00900+2.7.1.36;Reactome: R-HSA-191273;MetaCyc: PWY-6174;MetaCyc: PWY-7391 "Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)" XP_030027057.2 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_030022909.1 5 Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_037297743.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037297374.1 2 Reactome: R-HSA-3000178;MetaCyc: PWY-7511 "ECM proteoglycans";"Protein ubiquitination" XP_030028793.1 10 Reactome: R-HSA-5689880;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-9635644;Reactome: R-HSA-432720;Reactome: R-HSA-9636383;Reactome: R-HSA-917729;Reactome: R-HSA-8856825 "Ub-specific processing proteases";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"Inhibition of membrane repair";"Lysosome Vesicle Biogenesis";"Prevention of phagosomal-lysosomal fusion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Cargo recognition for clathrin-mediated endocytosis" XP_037302350.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_030041334.1 6 MetaCyc: PWY-8010;Reactome: R-HSA-977347;KEGG: 00260+2.6.1.52;KEGG: 00750+2.6.1.52;KEGG: 00680+2.6.1.52;KEGG: 00270+2.6.1.52 "L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Serine biosynthesis";"Glycine, serine and threonine metabolism";"Vitamin B6 metabolism";"Methane metabolism";"Cysteine and methionine metabolism" XP_030025253.2 2 Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_037292539.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_037297197.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-5620912 "AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane" XP_030024562.2 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_030032993.1 12 Reactome: R-HSA-6804756;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "Regulation of TP53 Activity through Phosphorylation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_030036138.2 6 Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_037294472.1 2 MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24 "Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis" XP_037302295.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_030020898.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_030033285.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037293673.1 7 Reactome: R-HSA-5674400;Reactome: R-HSA-165181;Reactome: R-HSA-198323;Reactome: R-HSA-1632852;Reactome: R-HSA-8854214;Reactome: R-HSA-5628897;Reactome: R-HSA-380972 "Constitutive Signaling by AKT1 E17K in Cancer";"Inhibition of TSC complex formation by PKB";"AKT phosphorylates targets in the cytosol";"Macroautophagy";"TBC/RABGAPs";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_037296029.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_037292687.1 6 Reactome: R-HSA-6804759;Reactome: R-HSA-6803205;Reactome: R-HSA-139915;Reactome: R-HSA-6803207;Reactome: R-HSA-6803211;Reactome: R-HSA-6803204 "Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_030041296.2 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_030033609.1 3 KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596 "Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I" XP_030039501.1 9 Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-674695 "HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events" XP_030023254.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_037294112.1 6 KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17;Reactome: R-HSA-379716;Reactome: R-HSA-6782315;Reactome: R-HSA-2408522;MetaCyc: PWY-5188 "Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"tRNA modification in the nucleus and cytosol";"Selenoamino acid metabolism";"Tetrapyrrole biosynthesis I (from glutamate)" XP_030023242.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_030023298.2 9 KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_037298908.1 2 Reactome: R-HSA-181429;Reactome: R-HSA-212676 "Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" XP_037296294.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_030021035.1 8 Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-8948747;Reactome: R-HSA-6782210;Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-8866652 "Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Regulation of PTEN localization";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Ub-specific processing proteases";"Regulation of TP53 Degradation";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes" XP_030024812.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_030040999.2 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_030020009.1 3 MetaCyc: PWY-6367;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6368 "D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation" XP_037296938.1 7 MetaCyc: PWY-5469;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-6824 "Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Justicidin B biosynthesis" XP_030026996.1 57 Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-5610780 "Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"Degradation of GLI1 by the proteasome" XP_030024887.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214847 "NoRC negatively regulates rRNA expression";"HATs acetylate histones" XP_037303399.1 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" XP_030023905.1 3 Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355 "Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction" XP_030024631.1 4 Reactome: R-HSA-1614603;KEGG: 00260+4.2.1.22;MetaCyc: PWY-801;KEGG: 00270+4.2.1.22 "Cysteine formation from homocysteine";"Glycine, serine and threonine metabolism";"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism" XP_030029788.2 7 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis" XP_030026758.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_030022193.2 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_030026783.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_037300912.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_037300371.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_030040081.2 24 Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-190861;Reactome: R-HSA-3371497 "COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Recycling pathway of L1";"Aggrephagy";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Cilium Assembly";"RHO GTPases Activate Formins";"HCMV Early Events";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_037294724.1 13 Reactome: R-HSA-5578775;Reactome: R-HSA-2871809;Reactome: R-HSA-5607763;Reactome: R-HSA-112043;Reactome: R-HSA-2029485;Reactome: R-HSA-139853;Reactome: R-HSA-114508;Reactome: R-HSA-381676;Reactome: R-HSA-4086398;Reactome: R-HSA-983695;Reactome: R-HSA-422356;Reactome: R-HSA-1489509;Reactome: R-HSA-5218921 "Ion homeostasis";"FCERI mediated Ca+2 mobilization";"CLEC7A (Dectin-1) induces NFAT activation";"PLC beta mediated events";"Role of phospholipids in phagocytosis";"Elevation of cytosolic Ca2+ levels";"Effects of PIP2 hydrolysis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Regulation of insulin secretion";"DAG and IP3 signaling";"VEGFR2 mediated cell proliferation" XP_030029989.2 5 Reactome: R-HSA-532668;KEGG: 00510+3.2.1.106;Reactome: R-HSA-4793954;MetaCyc: PWY-7919;MetaCyc: PWY-7918 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"N-Glycan biosynthesis";"Defective MOGS causes MOGS-CDG (CDG-2b)";"Protein N-glycosylation processing phase (plants and animals)";"Protein N-glycosylation processing phase (yeast)" XP_037300142.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037296695.1 8 Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68867 "Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex" XP_037292558.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5663220;Reactome: R-HSA-163560;Reactome: R-HSA-400253;Reactome: R-HSA-141444;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"T cell receptor signaling pathway";"RHO GTPases Activate Formins";"Triglyceride catabolism";"Circadian Clock";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation" XP_037300538.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_030021725.1 1 KEGG: 00270+2.1.1.37 "Cysteine and methionine metabolism" XP_030041121.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037300527.1 27 Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-159231 "Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_037295911.1 3 Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-381038 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"XBP1(S) activates chaperone genes" XP_030025317.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_037300129.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_030041062.2 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_030026782.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_030024453.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_037292288.1 1 Reactome: R-HSA-9617828 "FOXO-mediated transcription of cell cycle genes" XP_037303403.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_030028706.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037303566.1 7 Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-73980 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination" XP_037299864.1 11 KEGG: 04660+2.7.10.2;Reactome: R-HSA-983231;Reactome: R-HSA-8940973;Reactome: R-HSA-8939236;Reactome: R-HSA-428890;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-2029482;Reactome: R-HSA-525793;Reactome: R-HSA-5663213;Reactome: R-HSA-69231 "T cell receptor signaling pathway";"Factors involved in megakaryocyte development and platelet production";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Role of ABL in ROBO-SLIT signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"Regulation of actin dynamics for phagocytic cup formation";"Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"Cyclin D associated events in G1" XP_037292932.1 5 Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;Reactome: R-HSA-450321;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24 "Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway" XP_030027822.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_030035998.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_030036541.1 6 KEGG: 00010+5.4.2.11;KEGG: 00680+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-5484;KEGG: 00260+5.4.2.11;MetaCyc: PWY-8004 "Glycolysis / Gluconeogenesis";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Glycolysis II (from fructose 6-phosphate)";"Glycine, serine and threonine metabolism";"Entner-Doudoroff pathway I" XP_030021526.1 14 MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7619 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis" XP_030027531.2 9 MetaCyc: PWY-7385;MetaCyc: PWY-6118;MetaCyc: PWY-7902;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.8;KEGG: 00564+1.1.1.94;Reactome: R-HSA-1483166 "1,3-propanediol biosynthesis (engineered)";"Glycerol-3-phosphate shuttle";"Glucosylglycerol biosynthesis";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"Synthesis of PA" XP_030029584.2 6 KEGG: 00730+2.7.6.2;MetaCyc: PWY-7356;MetaCyc: PWY-6908;Reactome: R-HSA-196819;MetaCyc: PWY-6898;MetaCyc: PWY-6907 "Thiamine metabolism";"Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Vitamin B1 (thiamin) metabolism";"Thiamine salvage III";"Thiamine diphosphate biosynthesis III (Staphylococcus)" XP_037300261.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_037298905.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_037292231.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion" XP_037302087.1 11 Reactome: R-HSA-5663213;Reactome: R-HSA-69231;Reactome: R-HSA-5685938;Reactome: R-HSA-525793;Reactome: R-HSA-2029482;Reactome: R-HSA-5693565;Reactome: R-HSA-428890;Reactome: R-HSA-8939236;Reactome: R-HSA-8940973;Reactome: R-HSA-983231;KEGG: 04660+2.7.10.2 "RHO GTPases Activate WASPs and WAVEs";"Cyclin D associated events in G1";"HDR through Single Strand Annealing (SSA)";"Myogenesis";"Regulation of actin dynamics for phagocytic cup formation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Role of ABL in ROBO-SLIT signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX2 regulates osteoblast differentiation";"Factors involved in megakaryocyte development and platelet production";"T cell receptor signaling pathway" XP_037293344.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_030026709.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030026859.2 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_037298255.1 12 KEGG: 00230+2.7.4.8;Reactome: R-HSA-447038;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-451308;Reactome: R-HSA-438066;MetaCyc: PWY-7221 "Purine metabolism";"NrCAM interactions";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Guanosine ribonucleotides de novo biosynthesis" XP_037301994.1 27 Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-168276 "Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways" XP_030024079.2 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_037293927.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_037297926.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_030020287.2 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_037302882.1 3 Reactome: R-HSA-429947;Reactome: R-HSA-6804115;Reactome: R-HSA-5617472 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_030041123.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_030028227.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_037299991.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_030020377.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030025107.2 27 Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-4615885;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142 "Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA replication proteins";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins" XP_037292727.1 27 Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-4551638 "SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"snRNP Assembly";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins" XP_030028583.2 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037296726.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_037294726.1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490 "Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation" XP_037299683.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_030029890.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037293139.1 9 Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)" XP_037293486.1 9 Reactome: R-HSA-3371599;Reactome: R-HSA-70263;Reactome: R-HSA-196780;KEGG: 00720+6.4.1.1;KEGG: 00620+6.4.1.1;MetaCyc: PWY-6146;MetaCyc: PWY-6142;MetaCyc: PWY-8086;KEGG: 00020+6.4.1.1 "Defective HLCS causes multiple carboxylase deficiency";"Gluconeogenesis";"Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)" XP_030034306.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_030020543.2 2 Reactome: R-HSA-446193;Reactome: R-HSA-5633231 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)" XP_030032568.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_030021931.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_030023514.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-192823 "Eukaryotic Translation Termination";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation" XP_030024706.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_030031380.2 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_030033425.1 2 Reactome: R-HSA-5663220;Reactome: R-HSA-376176 "RHO GTPases Activate Formins";"Signaling by ROBO receptors" XP_030023825.2 6 Reactome: R-HSA-5099900;KEGG: 04070+2.7.11.13;Reactome: R-HSA-76005;Reactome: R-HSA-416993;Reactome: R-HSA-114516;Reactome: R-HSA-418597 "WNT5A-dependent internalization of FZD4";"Phosphatidylinositol signaling system";"Response to elevated platelet cytosolic Ca2+";"Trafficking of GluR2-containing AMPA receptors";"Disinhibition of SNARE formation";"G alpha (z) signalling events" XP_030038641.1 5 Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-168164 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade" XP_030035108.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway" XP_030032916.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037302867.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_030029230.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_030027497.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_030023185.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" XP_030035947.1 2 Reactome: R-HSA-2151201;KEGG: 00970+6.1.1.14 "Transcriptional activation of mitochondrial biogenesis";"Aminoacyl-tRNA biosynthesis" XP_030028072.2 56 Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-4641258;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176 "SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of DVL";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha" XP_030024944.2 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_030029188.1 1 Reactome: R-HSA-2465910 "MASTL Facilitates Mitotic Progression" XP_030038948.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Eukaryotic Translation Termination" XP_030019796.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-5205685 "Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy" XP_030022781.2 5 Reactome: R-HSA-193048;MetaCyc: PWY-6129;Reactome: R-HSA-4755579;Reactome: R-HSA-446199;KEGG: 00510+1.3.1.94 "Androgen biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis" XP_037299450.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7725 "Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_037292856.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-6798695;Reactome: R-HSA-2029482 "Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation";"Regulation of actin dynamics for phagocytic cup formation" XP_037300560.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_037299982.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_037302846.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_030040897.2 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_030041386.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823 "Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex" XP_037293735.1 17 KEGG: 05165+2.7.11.1;Reactome: R-HSA-1221632;Reactome: R-HSA-176187;Reactome: R-HSA-6796648;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6783310;Reactome: R-HSA-6804756;Reactome: R-HSA-3371453;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693607;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693616 "Human papillomavirus infection";"Meiotic synapsis";"Activation of ATR in response to replication stress";"TP53 Regulates Transcription of DNA Repair Genes";"mTOR signaling pathway";"Fanconi Anemia Pathway";"Regulation of TP53 Activity through Phosphorylation";"Regulation of HSF1-mediated heat shock response";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Thermogenesis";"Human cytomegalovirus infection";"Processing of DNA double-strand break ends";"Human immunodeficiency virus 1 infection";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_037294004.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037299120.1 5 Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"Cargo concentration in the ER" XP_037297639.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_030022609.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_030033167.1 17 Reactome: R-HSA-74259;Reactome: R-HSA-74217;MetaCyc: PWY-6611;MetaCyc: PWY-6620;KEGG: 00760+2.4.2.1;KEGG: 00230+2.4.2.1;MetaCyc: PWY-7179-1;Reactome: R-HSA-6798695;MetaCyc: PWY-6609;KEGG: 00240+2.4.2.1;MetaCyc: PWY-4202;MetaCyc: PWY-6644;MetaCyc: PWY-5532;MetaCyc: PWY-7179;MetaCyc: PWY-5695;MetaCyc: PWY-6627;MetaCyc: PWY-6608 "Purine catabolism";"Purine salvage";"Adenine and adenosine salvage V";"Guanine and guanosine salvage";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Purine deoxyribonucleosides degradation II";"Neutrophil degranulation";"Adenine and adenosine salvage III";"Pyrimidine metabolism";"Arsenate detoxification I (mammalian)";"Fluoroacetate and fluorothreonine biosynthesis";"Nucleoside and nucleotide degradation (archaea)";"Purine deoxyribonucleosides degradation I";"Inosine 5'-phosphate degradation";"Salinosporamide A biosynthesis";"Guanosine nucleotides degradation III" XP_030032265.2 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_037299586.1 10 Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5684264;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-2565942;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-202424 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Regulation of PLK1 Activity at G2/M Transition";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling" XP_030021775.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_037295854.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_030036032.2 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_030041075.2 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_037293517.1 16 Reactome: R-HSA-5693554;Reactome: R-HSA-3214847;Reactome: R-HSA-9018519;Reactome: R-HSA-5693548;Reactome: R-HSA-5685942;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HATs acetylate histones";"Estrogen-dependent gene expression";"Sensing of DNA Double Strand Breaks";"HDR through Homologous Recombination (HRR)";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange" XP_037292966.1 42 MetaCyc: PWY-6945;KEGG: 00640+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;MetaCyc: PWY-1361;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00623+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;KEGG: 00410+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;MetaCyc: PWY-7656;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;MetaCyc: PWY-6863;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;MetaCyc: PWY-6946;MetaCyc: PWY-7216;MetaCyc: PWY-7007;MetaCyc: PWY-6883;MetaCyc: PWY-5177;MetaCyc: PWY-7401;MetaCyc: PWY-6583;KEGG: 00627+4.2.1.17;MetaCyc: PWY-5109;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7654;MetaCyc: PWY-6944;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;MetaCyc: PWY-5138 "Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Propanoate metabolism";"Valine, leucine and isoleucine degradation";"Methyl tert-butyl ether degradation";"Fatty acid degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Benzoyl-coa degradation I (aerobic)";"Fatty acid elongation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Toluene degradation";"Carbon fixation pathways in prokaryotes";"alpha-Linolenic acid metabolism";"Lysine degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism";"Tryptophan metabolism";"2-methylpropene degradation";"Fatty acid degradation";"Fatty acid salvage";"Spodoptera littoralis pheromone biosynthesis";"Butanoate metabolism";"Geraniol degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Pyruvate fermentation to hexanol (engineered)";"Caprolactam degradation";"Limonene and pinene degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Methyl ketone biosynthesis (engineered)";"Pyruvate fermentation to butanol II (engineered)";"Glutaryl-coa degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Pyruvate fermentation to butanol I";"Aminobenzoate degradation";"Fermentation to 2-methylbutanoate";"Phenylalanine metabolism";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Androstenedione degradation";"Benzoate degradation";"Butanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation IV (unsaturated, even number)" XP_037302412.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_037297927.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_030032186.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_030032521.1 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_030021077.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037295314.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037299248.1 18 MetaCyc: PWY-5537;Reactome: R-HSA-163765;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5690;MetaCyc: PWY-5913;MetaCyc: PWY-6728;KEGG: 00640+6.2.1.5;MetaCyc: PWY-7384;Reactome: R-HSA-6798695;MetaCyc: PWY-5172;Reactome: R-HSA-75105;MetaCyc: PWY-6969;KEGG: 00720+6.2.1.5;KEGG: 00720+2.3.3.8;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5538;KEGG: 00020+6.2.1.5 "Pyruvate fermentation to acetate V";"ChREBP activates metabolic gene expression";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Neutrophil degranulation";"Acetyl-coa biosynthesis III (from citrate)";"Fatty acyl-CoA biosynthesis";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"Pyruvate fermentation to acetate VI";"Citrate cycle (TCA cycle)" XP_030036354.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037297064.1 15 Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-111465;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-195253;Reactome: R-HSA-3769402;Reactome: R-HSA-5467340;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-5467337;Reactome: R-HSA-196299;Reactome: R-HSA-5689896;Reactome: R-HSA-5467333;Reactome: R-HSA-5358749 "Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"Deactivation of the beta-catenin transactivating complex";"AXIN missense mutants destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Beta-catenin phosphorylation cascade";"Ovarian tumor domain proteases";"APC truncation mutants are not K63 polyubiquitinated";"S37 mutants of beta-catenin aren't phosphorylated" XP_037294236.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037293785.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_030032600.1 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" XP_030022226.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_037300863.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_030028105.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation";"RHO GTPases activate KTN1" XP_030025947.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_037301546.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_037294622.1 9 Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-191859;Reactome: R-HSA-400253 "Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"snRNP Assembly";"Circadian Clock" XP_030038620.1 5 Reactome: R-HSA-937041;Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-168164 "IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade" XP_037295168.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_030029520.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_037300858.1 6 KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-163560 "T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"Triglyceride catabolism" XP_037296889.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_037303562.1 3 KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282;Reactome: R-HSA-2024096 "Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B";"HS-GAG degradation" XP_030031104.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030030225.2 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_037297536.1 6 MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism" XP_037303463.1 6 MetaCyc: PWY-6367;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.64+3.1.3.95;KEGG: 00562+3.1.3.64+3.1.3.95;MetaCyc: PWY-6580;MetaCyc: PWY-6368 "D-myo-inositol-5-phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)";"3-phosphoinositide degradation" XP_037302890.1 3 Reactome: R-HSA-6804115;Reactome: R-HSA-429947;Reactome: R-HSA-5617472 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_037294160.1 4 Reactome: R-HSA-975144;MetaCyc: PWY-7511;Reactome: R-HSA-9020702;Reactome: R-HSA-937039 "IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Protein ubiquitination";"Interleukin-1 signaling";"IRAK1 recruits IKK complex" XP_030040594.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_030041119.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037293695.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_030032269.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_037301186.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037302947.1 6 Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-181429 "Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_030031664.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_030025455.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030038979.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_030034694.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_030024760.1 11 MetaCyc: PWY-7254;KEGG: 00480+1.1.1.42;MetaCyc: PWY-5913;MetaCyc: PWY-6969;MetaCyc: PWY-6549;MetaCyc: PWY-7268;MetaCyc: PWY-7124;MetaCyc: PWY-6728;Reactome: R-HSA-71403;KEGG: 00720+1.1.1.42;KEGG: 00020+1.1.1.42 "TCA cycle VII (acetate-producers)";"Glutathione metabolism";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"L-glutamine biosynthesis III";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Ethylene biosynthesis V (engineered)";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)" XP_037295970.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_037300337.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_030025615.1 17 Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-6790901;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72706 "Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037293655.1 6 KEGG: 00630+4.2.1.3;Reactome: R-HSA-1268020;KEGG: 00720+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;Reactome: R-HSA-71403 "Glyoxylate and dicarboxylate metabolism";"Mitochondrial protein import";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Citric acid cycle (TCA cycle)" XP_030028605.2 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_030023008.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_030032002.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_030021722.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_030021252.1 14 Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-2022377;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156902 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Metabolism of Angiotensinogen to Angiotensins";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Peptide chain elongation" XP_037293647.1 4 Reactome: R-HSA-201681;Reactome: R-HSA-418594;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880 "TCF dependent signaling in response to WNT";"G alpha (i) signalling events";"Degradation of AXIN";"Ub-specific processing proteases" XP_030026739.2 1 Reactome: R-HSA-5627083 "RHO GTPases regulate CFTR trafficking" XP_037296498.1 4 Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761 "NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling" XP_030035697.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_030026801.2 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_030036035.2 2 Reactome: R-HSA-3108214;Reactome: R-HSA-5685938 "SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)" XP_030035172.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_030025248.2 2 Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_037300196.1 5 Reactome: R-HSA-5083630;Reactome: R-HSA-350054;Reactome: R-HSA-1912399;Reactome: R-HSA-1912408;Reactome: R-HSA-1912420 "Defective LFNG causes SCDO3";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in Golgi" XP_030023826.2 6 Reactome: R-HSA-416993;KEGG: 04070+2.7.11.13;Reactome: R-HSA-76005;Reactome: R-HSA-5099900;Reactome: R-HSA-418597;Reactome: R-HSA-114516 "Trafficking of GluR2-containing AMPA receptors";"Phosphatidylinositol signaling system";"Response to elevated platelet cytosolic Ca2+";"WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events";"Disinhibition of SNARE formation" XP_030034774.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030032926.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_030031328.1 12 Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-141444 "RHO GTPases Activate Formins";"HCMV Early Events";"Aggrephagy";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_037292658.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037298629.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037295093.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_037300943.1 4 Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_030035973.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_030030177.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030040920.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_030031095.2 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_037300277.1 5 MetaCyc: PWY-7922;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)" XP_037302541.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_030024558.2 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_030027380.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030036259.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_030028331.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_030028372.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037292424.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-936837 "Neutrophil degranulation";"Ion transport by P-type ATPases" XP_037295862.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_037293029.1 2 Reactome: R-HSA-70263;Reactome: R-HSA-70171 "Gluconeogenesis";"Glycolysis" XP_037295106.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_030032183.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_030020080.2 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_030019686.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037298057.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037302418.1 3 Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5655862 "Translesion synthesis by POLI";"Translesion synthesis by REV1";"Translesion synthesis by POLK" XP_030023501.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-5689880 "Protein ubiquitination";"Ub-specific processing proteases" XP_030028570.1 8 Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;KEGG: 00195+7.1.2.2;Reactome: R-HSA-983712;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Photosynthesis";"Ion channel transport";"Oxidative phosphorylation";"ATP biosynthesis";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_030040846.2 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_030024701.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030035149.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_030036673.1 56 Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-75815 "Degradation of AXIN";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D" XP_030020531.1 9 Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-6804756 "RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation" XP_030037272.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-429958 "Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease" XP_030036232.1 13 MetaCyc: PWY-7210;MetaCyc: PWY-7227;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7226;KEGG: 00240+1.17.4.1;MetaCyc: PWY-6545;MetaCyc: PWY-7220;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7222;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" XP_037300496.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_030019707.1 12 Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-6804756;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167287 "Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery" XP_030028985.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037297651.1 4 MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49;MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"Glutathione metabolism" XP_030037068.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037297444.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" XP_037296625.1 15 MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-7218;KEGG: 00230+2.7.1.40;MetaCyc: PWY-5723;MetaCyc: PWY-6886;MetaCyc: PWY-8004;KEGG: 00620+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-7383;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-7003 "Glycolysis IV (plant cytosol)";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Purine metabolism";"Rubisco shunt";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Pyruvate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol" XP_030019701.1 3 KEGG: 00260+3.1.3.3;KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347 "Glycine, serine and threonine metabolism";"Methane metabolism";"Serine biosynthesis" XP_037299378.1 6 Reactome: R-HSA-3214815;Reactome: R-HSA-1989781;Reactome: R-HSA-9029569;Reactome: R-HSA-9022537;Reactome: R-HSA-9022692;Reactome: R-HSA-9609690 "HDACs deacetylate histones";"PPARA activates gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"Regulation of MECP2 expression and activity";"HCMV Early Events" XP_030035727.2 7 Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-73980 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination" XP_030035253.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_037292515.1 14 MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-5972 "Juniperonate biosynthesis";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)" XP_037292974.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_037300000.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_037298377.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037302495.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_030037369.1 2 KEGG: 00052+3.2.1.26;KEGG: 00500+3.2.1.26 "Galactose metabolism";"Starch and sucrose metabolism" XP_030029869.1 6 Reactome: R-HSA-427359;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-5250924 "SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression" XP_037297360.1 8 Reactome: R-HSA-71336;Reactome: R-HSA-6791055;Reactome: R-HSA-163754;MetaCyc: PWY-5723;Reactome: R-HSA-8950505;KEGG: 00030+2.2.1.2;Reactome: R-HSA-6791462;MetaCyc: PWY-1861 "Pentose phosphate pathway";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Rubisco shunt";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Pentose phosphate pathway";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" XP_037298049.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037295388.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_037294448.1 12 KEGG: 04150+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04926+2.7.11.1;Reactome: R-HSA-193648;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5655302;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1839117;Reactome: R-HSA-194840;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"G alpha (12/13) signalling events";"Relaxin signaling pathway";"NRAGE signals death through JNK";"Human papillomavirus infection";"Signaling by FGFR1 in disease";"PI3K-Akt signaling pathway";"Signaling by cytosolic FGFR1 fusion mutants";"Rho GTPase cycle";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis" XP_037293557.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_037303270.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_037298511.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037296937.1 7 MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-6824 "Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Justicidin B biosynthesis" XP_030027803.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037297873.1 2 Reactome: R-HSA-5663220;Reactome: R-HSA-376176 "RHO GTPases Activate Formins";"Signaling by ROBO receptors" XP_030027515.2 9 MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-7385;MetaCyc: PWY-6118;MetaCyc: PWY-7902;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.8;KEGG: 00564+1.1.1.94 "Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"1,3-propanediol biosynthesis (engineered)";"Glycerol-3-phosphate shuttle";"Glucosylglycerol biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Glycerophospholipid metabolism" XP_030034161.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_030036783.2 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_030037920.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030019874.2 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_037298140.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_030029007.1 3 Reactome: R-HSA-6784531;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766 "tRNA processing in the nucleus";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion" XP_037293391.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037295930.1 1 Reactome: R-HSA-390696 "Adrenoceptors" XP_030036711.2 12 MetaCyc: PWY-1042;Reactome: R-HSA-70263;Reactome: R-HSA-70171;KEGG: 00680+4.1.2.13;KEGG: 00051+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-7385;KEGG: 00710+4.1.2.13;MetaCyc: PWY-1861;KEGG: 00030+4.1.2.13;KEGG: 00010+4.1.2.13 "Glycolysis IV (plant cytosol)";"Gluconeogenesis";"Glycolysis";"Methane metabolism";"Fructose and mannose metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis" XP_030040191.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_037302293.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037293657.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037296961.1 7 Reactome: R-HSA-5617472;Reactome: R-HSA-8953750;Reactome: R-HSA-2559580;Reactome: R-HSA-9609690;Reactome: R-HSA-3214841;Reactome: R-HSA-8943724;Reactome: R-HSA-212300 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional Regulation by E2F6";"Oxidative Stress Induced Senescence";"HCMV Early Events";"PKMTs methylate histone lysines";"Regulation of PTEN gene transcription";"PRC2 methylates histones and DNA" XP_030034474.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_030025967.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-73980 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination" XP_030026415.1 9 MetaCyc: PWY-6964;MetaCyc: PWY-6549;KEGG: 00250+6.3.1.2;KEGG: 00220+6.3.1.2;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6963;KEGG: 00630+6.3.1.2;MetaCyc: PWY-5675;MetaCyc: PWY-381 "Ammonia assimilation cycle II";"L-glutamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Nitrogen metabolism";"Ammonia assimilation cycle I";"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction V (assimilatory)";"Nitrate reduction II (assimilatory)" XP_037298842.1 11 KEGG: 00910+6.3.1.2;KEGG: 00220+6.3.1.2;Reactome: R-HSA-210455;MetaCyc: PWY-6549;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6964;Reactome: R-HSA-8964539;MetaCyc: PWY-381;MetaCyc: PWY-5675;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6963 "Nitrogen metabolism";"Arginine biosynthesis";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"L-glutamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle II";"Glutamate and glutamine metabolism";"Nitrate reduction II (assimilatory)";"Nitrate reduction V (assimilatory)";"Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle I" XP_030031767.1 7 MetaCyc: PWY-5469;MetaCyc: PWY-5461;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5466 "Sesamin biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Matairesinol biosynthesis" XP_030022259.1 1 Reactome: R-HSA-350562 "Regulation of ornithine decarboxylase (ODC)" XP_030029483.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037294613.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_037292828.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_030028452.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_030027762.1 11 MetaCyc: PWY-3861;MetaCyc: PWY-5659;Reactome: R-HSA-4043916;MetaCyc: PWY-3881;MetaCyc: PWY-7456;KEGG: 00520+5.3.1.8;MetaCyc: PWY-882;KEGG: 00051+5.3.1.8;MetaCyc: PWY-7586;MetaCyc: PWY-6992;Reactome: R-HSA-446205 "Mannitol degradation II";"GDP-mannose biosynthesis";"Defective MPI causes MPI-CDG (CDG-1b)";"Mannitol biosynthesis";"Beta-(1,4)-mannan degradation";"Amino sugar and nucleotide sugar metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Fructose and mannose metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"1,5-anhydrofructose degradation";"Synthesis of GDP-mannose" XP_037293696.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037298382.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_030029150.2 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_030021514.1 5 KEGG: 00230+6.3.5.3;MetaCyc: PWY-6277;Reactome: R-HSA-73817;MetaCyc: PWY-6122;MetaCyc: PWY-6121 "Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I" XP_037292606.1 5 Reactome: R-HSA-2894862;Reactome: R-HSA-3214815;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription" XP_030020351.2 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_030026666.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-2173788 "UCH proteinases";"Downregulation of TGF-beta receptor signaling" XP_030025539.2 7 Reactome: R-HSA-8949613;Reactome: R-HSA-2151201;Reactome: R-HSA-163210;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-1268020 "Cristae formation";"Transcriptional activation of mitochondrial biogenesis";"Formation of ATP by chemiosmotic coupling";"ATP biosynthesis";"Oxidative phosphorylation";"Photosynthesis";"Mitochondrial protein import" XP_037294495.1 7 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway" XP_037297144.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037299729.1 1 Reactome: R-HSA-2024096 "HS-GAG degradation" XP_037294065.1 5 Reactome: R-HSA-901032;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-381038;MetaCyc: PWY-7511 "ER Quality Control Compartment (ERQC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"XBP1(S) activates chaperone genes";"Protein ubiquitination" XP_037292759.1 5 Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-5675221;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Negative regulation of MAPK pathway";"Signaling by moderate kinase activity BRAF mutants";"RAF activation" XP_037297147.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_030031341.1 3 MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695 "Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Neutrophil degranulation" XP_037297422.1 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160 "T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions" XP_030029571.1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" XP_030031018.1 29 Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-3371453;Reactome: R-HSA-6804756;Reactome: R-HSA-5655862;Reactome: R-HSA-68962;Reactome: R-HSA-5651801;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395;Reactome: R-HSA-5693616;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-69166;Reactome: R-HSA-5696397;Reactome: R-HSA-5358606;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-176187;Reactome: R-HSA-5358565;Reactome: R-HSA-110314;Reactome: R-HSA-912446;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-5656121;Reactome: R-HSA-174437;Reactome: R-HSA-110312;Reactome: R-HSA-6783310;Reactome: R-HSA-3371511 "HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Regulation of HSF1-mediated heat shock response";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLK";"Activation of the pre-replicative complex";"PCNA-Dependent Long Patch Base Excision Repair";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Activation of ATR in response to replication stress";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Recognition of DNA damage by PCNA-containing replication complex";"Meiotic recombination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Translesion synthesis by POLI";"Removal of the Flap Intermediate from the C-strand";"Translesion synthesis by REV1";"Fanconi Anemia Pathway";"HSF1 activation" XP_030025255.2 2 Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_030033237.1 14 MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7725 "Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_037299572.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_037299992.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_030027544.1 3 Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (i) signalling events";"G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_037297675.1 6 MetaCyc: PWY-6118;MetaCyc: PWY-6952;Reactome: R-HSA-1483166;Reactome: R-HSA-163560;KEGG: 00564+1.1.5.3;MetaCyc: PWY-4261 "Glycerol-3-phosphate shuttle";"Glycerophosphodiester degradation";"Synthesis of PA";"Triglyceride catabolism";"Glycerophospholipid metabolism";"Glycerol degradation I" XP_037300264.1 14 MetaCyc: PWY-6453;MetaCyc: PWY-5981;MetaCyc: PWY-8051;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7589;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7411;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.51 "Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism" XP_037303013.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_030026023.2 3 Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.19 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_037297445.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" XP_037293815.1 13 KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7222;Reactome: R-HSA-499943;MetaCyc: PWY-7220;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7210;MetaCyc: PWY-7227 "Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis" XP_037295876.1 6 KEGG: 00562+3.1.3.56;MetaCyc: PWY-6362;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364;Reactome: R-HSA-1855183;MetaCyc: PWY-6363 "Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation" XP_030028103.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "MHC class II antigen presentation";"RHO GTPases activate KTN1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_030034323.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_030035606.1 3 Reactome: R-HSA-8963684;Reactome: R-HSA-156590;Reactome: R-HSA-204174 "Tyrosine catabolism";"Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_037302715.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_030027986.1 2 KEGG: 00230+3.5.3.4;MetaCyc: PWY-5697 "Purine metabolism";"Allantoin degradation to ureidoglycolate I (urea producing)" XP_037296711.1 14 MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;Reactome: R-HSA-975634;MetaCyc: PWY-6803;MetaCyc: PWY-7417;MetaCyc: PWY-8053;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416 "Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Plasmalogen degradation";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Retinoid metabolism and transport";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)" XP_030038921.1 3 MetaCyc: PWY-7277;KEGG: 00600+3.1.4.12;Reactome: R-HSA-1660662 "Sphingolipid biosynthesis (mammals)";"Sphingolipid metabolism";"Glycosphingolipid metabolism" XP_030026241.2 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_030021960.1 11 Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-69166;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-174437;Reactome: R-HSA-5693554 "HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Removal of the Flap Intermediate";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Removal of the Flap Intermediate from the C-strand";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_037292723.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_037296917.1 5 Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-176974 "Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA" XP_030021232.1 22 MetaCyc: PWY-7725;MetaCyc: PWY-7728;MetaCyc: PWY-7592;MetaCyc: PWY-6958;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7606;MetaCyc: PWY-7602;MetaCyc: PWY-5353;MetaCyc: PWY-7049;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;Reactome: R-HSA-75876;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7619;MetaCyc: PWY-7053;MetaCyc: PWY-7727;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7726 "Arachidonate biosynthesis V (8-detaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Juniperonate biosynthesis";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)" XP_030032392.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_030031845.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_030034965.2 6 Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-6804756 "Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation" XP_037294244.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_037300501.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037294246.1 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_037298664.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_030041125.1 3 MetaCyc: PWY-5691;KEGG: 00232+1.7.3.3;KEGG: 00230+1.7.3.3 "Urate conversion to allantoin I";"Caffeine metabolism";"Purine metabolism" XP_030026680.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_037292455.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037294926.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_037297356.1 2 Reactome: R-HSA-3000178;MetaCyc: PWY-7511 "ECM proteoglycans";"Protein ubiquitination" XP_030036090.1 4 MetaCyc: PWY-6557;Reactome: R-HSA-1971475;KEGG: 00532+2.4.2.26;KEGG: 00534+2.4.2.26 "Glycosaminoglycan-protein linkage region biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin" XP_037297454.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-2024096;Reactome: R-HSA-2206291 "Neutrophil degranulation";"HS-GAG degradation";"MPS IIIC - Sanfilippo syndrome C" XP_037292843.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_037298482.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037294604.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037299076.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037300144.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037298817.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_030029707.1 7 Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-165159 "TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Macroautophagy";"mTORC1-mediated signalling";"mTOR signalling" XP_037297540.1 2 Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_030026845.2 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037296087.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_030024863.2 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_037301161.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037295336.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037298689.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-390918 "Peroxisomal protein import";"Peroxisomal lipid metabolism" XP_037300197.1 5 Reactome: R-HSA-350054;Reactome: R-HSA-5083630;Reactome: R-HSA-1912399;Reactome: R-HSA-1912408;Reactome: R-HSA-1912420 "Notch-HLH transcription pathway";"Defective LFNG causes SCDO3";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in Golgi" XP_030026848.2 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_030027743.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037301277.1 13 Reactome: R-HSA-1489509;Reactome: R-HSA-5218921;Reactome: R-HSA-983695;Reactome: R-HSA-422356;Reactome: R-HSA-114508;Reactome: R-HSA-381676;Reactome: R-HSA-4086398;Reactome: R-HSA-112043;Reactome: R-HSA-139853;Reactome: R-HSA-2029485;Reactome: R-HSA-5607763;Reactome: R-HSA-5578775;Reactome: R-HSA-2871809 "DAG and IP3 signaling";"VEGFR2 mediated cell proliferation";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Regulation of insulin secretion";"Effects of PIP2 hydrolysis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway";"PLC beta mediated events";"Elevation of cytosolic Ca2+ levels";"Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation";"Ion homeostasis";"FCERI mediated Ca+2 mobilization" XP_030026872.1 7 Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-166208 "Macroautophagy";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"mTOR signalling";"mTORC1-mediated signalling" XP_030023844.1 56 Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-5362768;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-8852276 "ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Vpu mediated degradation of CD4";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint" XP_030041258.1 3 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109 "Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis" XP_037303401.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030032630.2 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380284 "Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_030023845.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030023879.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_030022938.1 11 Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-3371497;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-8854518 "Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"AURKA Activation by TPX2" XP_030020347.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037297353.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_037299132.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7724 "Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_030028153.2 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_037302383.1 3 Reactome: R-HSA-5696395;Reactome: R-HSA-5689877;Reactome: R-HSA-5696394 "Formation of Incision Complex in GG-NER";"Josephin domain DUBs";"DNA Damage Recognition in GG-NER" XP_037303367.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037301744.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_037294407.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606 "NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_030019835.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037302707.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_030021164.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_037300267.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037299489.1 14 MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7602 "Juniperonate biosynthesis";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_030023727.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947 "Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription" XP_037294090.1 8 Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-8953750;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-912446 "Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Transcriptional Regulation by E2F6";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination" XP_030040156.2 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_030027151.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_030031779.1 7 MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-7214 "Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)" XP_030033635.1 3 Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596 "Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I" XP_030031268.2 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_037296511.1 2 Reactome: R-HSA-174403;Reactome: R-HSA-5578998 "Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)" XP_037300705.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_030028922.1 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_030020093.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037294697.1 5 Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-983170 "Cargo concentration in the ER";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" XP_037292514.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-6598;Reactome: R-HSA-75876 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs" XP_030026830.2 14 MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;Reactome: R-HSA-75109;KEGG: 00565+3.1.3.4;Reactome: R-HSA-1483213;MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052;Reactome: R-HSA-4419969;Reactome: R-HSA-1483191;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8053 "Plasmalogen biosynthesis";"Glycerolipid metabolism";"Triglyceride biosynthesis";"Ether lipid metabolism";"Synthesis of PE";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Depolymerisation of the Nuclear Lamina";"Synthesis of PC";"Glycerophospholipid metabolism";"Anandamide biosynthesis II" XP_037298401.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_037297653.1 18 Reactome: R-HSA-1483166;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482801;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1482922;MetaCyc: PWY-7409;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;MetaCyc: PWY-6803;MetaCyc: PWY-7417 "Synthesis of PA";"Linoleic acid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PS";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Acyl chain remodelling of PG";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)" XP_037294092.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823 "mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex" XP_037298285.1 8 Reactome: R-HSA-1445148;Reactome: R-HSA-380972;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-5628897;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;Reactome: R-HSA-1632852 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"Macroautophagy" XP_037294891.1 8 KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway" XP_030037216.2 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" XP_037293191.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-164843;Reactome: R-HSA-1834949;Reactome: R-HSA-3270619;Reactome: R-HSA-5693571 "Neutrophil degranulation";"2-LTR circle formation";"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)" XP_030029889.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320 "Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes" XP_030040334.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037301901.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" XP_030036706.2 1 Reactome: R-HSA-8951664 "Neddylation" XP_037295066.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_037294116.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_030026850.2 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_030035096.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_037295508.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation" XP_037298050.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030031566.1 10 Reactome: R-HSA-5693607;Reactome: R-HSA-3108214;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756 "Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation" XP_030028579.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037301864.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_030034695.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_030031517.1 8 KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083629;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;MetaCyc: PWY-7922;MetaCyc: PWY-7921 "Mannose type O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)" XP_037295838.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030026567.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030040726.2 2 Reactome: R-HSA-8853659;Reactome: R-HSA-5673001 "RET signaling";"RAF/MAP kinase cascade" XP_030031469.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_037294500.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037302369.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_030024805.2 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_030029108.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-429958 "Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease" XP_030027853.2 7 Reactome: R-HSA-9018519;Reactome: R-HSA-5625886;Reactome: R-HSA-8943724;Reactome: R-HSA-983231;Reactome: R-HSA-9029569;Reactome: R-HSA-3214842;Reactome: R-HSA-3214815 "Estrogen-dependent gene expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Regulation of PTEN gene transcription";"Factors involved in megakaryocyte development and platelet production";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDMs demethylate histones";"HDACs deacetylate histones" XP_037300706.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_030026590.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_037300973.1 5 MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-6902 "Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)" XP_030032512.2 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_030036781.2 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_030034689.2 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_030040820.1 2 Reactome: R-HSA-425397;Reactome: R-HSA-5619061 "Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)" XP_037294534.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_037293474.1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway" XP_037296506.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_037296034.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_030036202.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_037293902.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030040819.1 2 Reactome: R-HSA-425397;Reactome: R-HSA-5619061 "Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)" XP_037294341.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_037297398.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_030024215.2 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_037292224.1 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" XP_030036723.2 4 MetaCyc: PWY-6829;Reactome: R-HSA-6782861;MetaCyc: PWY-7286;MetaCyc: PWY-7285 "Trna methylation (yeast)";"Synthesis of wybutosine at G37 of tRNA(Phe)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis" XP_030023243.1 4 Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_037299967.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_030038563.2 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_037296274.1 6 Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-388844 "Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases" XP_030035575.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_030020202.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037302895.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825 "DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis" XP_037293221.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037299312.1 5 Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-6804757 "VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation" XP_030020476.1 24 Reactome: R-HSA-9010642;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-9634600;Reactome: R-HSA-422356;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.11;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-442720;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-163560;Reactome: R-HSA-983231;Reactome: R-HSA-5610783;Reactome: R-HSA-111931;Reactome: R-HSA-5610785;Reactome: R-HSA-163358;Reactome: R-HSA-5621575;Reactome: R-HSA-8963896;Reactome: R-HSA-8853659;Reactome: R-HSA-392517 "ROBO receptors bind AKAP5";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Regulation of insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Triglyceride catabolism";"Factors involved in megakaryocyte development and platelet production";"Degradation of GLI2 by the proteasome";"PKA-mediated phosphorylation of CREB";"GLI3 is processed to GLI3R by the proteasome";"PKA-mediated phosphorylation of key metabolic factors";"CD209 (DC-SIGN) signaling";"HDL assembly";"RET signaling";"Rap1 signalling" XP_037301906.1 18 MetaCyc: PWY-8053;Reactome: R-HSA-1482801;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-6803;MetaCyc: PWY-7417;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-8051;Reactome: R-HSA-1482925;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4 "Anandamide biosynthesis II";"Acyl chain remodelling of PS";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Synthesis of PA";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Acyl chain remodelling of PI";"Anandamide biosynthesis I";"Acyl chain remodelling of PG";"Plasmalogen degradation";"Arachidonic acid metabolism" XP_030031376.2 3 Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism" XP_030026613.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037299608.1 2 MetaCyc: PWY-6558;Reactome: R-HSA-2022928 "Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis" XP_037294195.1 3 MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217 "Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage" XP_037294093.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_037297961.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_030034156.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_030031587.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037299851.1 13 KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5687128;KEGG: 05170+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-3928662;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416476;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"Thermogenesis";"MAPK6/MAPK4 signaling";"Human immunodeficiency virus 1 infection";"Rho GTPase cycle";"NRAGE signals death through JNK";"EPHB-mediated forward signaling";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"G alpha (12/13) signalling events";"mTOR signaling pathway";"G alpha (q) signalling events";"Relaxin signaling pathway" XP_037297082.1 7 MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461 "Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Betanidin degradation" XP_030021133.1 8 KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Signaling by Hippo";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection" XP_030033272.2 2 KEGG: 00051+5.3.1.5;KEGG: 00040+5.3.1.5 "Fructose and mannose metabolism";"Pentose and glucuronate interconversions" XP_037301218.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037299137.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_030032159.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_037300207.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_030023736.2 3 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_037301222.1 10 MetaCyc: PWY-5667;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-6453 "CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Stigma estolide biosynthesis" XP_030026238.1 7 Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_030033494.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607 "Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends" XP_030029670.1 13 MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52 "Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"CS/DS degradation";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series" XP_030026289.1 3 Reactome: R-HSA-1660662;Reactome: R-HSA-193681;Reactome: R-HSA-5626978 "Glycosphingolipid metabolism";"Ceramide signalling";"TNFR1-mediated ceramide production" XP_037303448.1 5 Reactome: R-HSA-9614657;Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-380994;Reactome: R-HSA-1989781 "FOXO-mediated transcription of cell death genes";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression" XP_037297967.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-192823 "Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation" XP_030024605.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_030023333.1 2 Reactome: R-HSA-71240;KEGG: 00380+1.13.11.11 "Tryptophan catabolism";"Tryptophan metabolism" XP_037300520.1 5 MetaCyc: PWY-5189;KEGG: 00860+4.2.1.24;Reactome: R-HSA-189451;MetaCyc: PWY-5188;Reactome: R-HSA-6798695 "Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Neutrophil degranulation" XP_030035767.1 6 MetaCyc: PWY-6906;KEGG: 00520+3.5.1.25;MetaCyc: PWY-7077;Reactome: R-HSA-446210;KEGG: 00052+3.5.1.25;MetaCyc: PWY-7395 "Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"N-acetyl-D-galactosamine degradation";"Synthesis of UDP-N-acetyl-glucosamine";"Galactose metabolism";"D-galactosamine and N-acetyl-D-galactosamine degradation" XP_037294364.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_037298740.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_030037368.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_037297569.1 2 Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_030025959.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_037299547.1 1 Reactome: R-HSA-73621 "Pyrimidine catabolism" XP_037294202.1 2 Reactome: R-HSA-429958;Reactome: R-HSA-390471 "mRNA decay by 3' to 5' exoribonuclease";"Association of TriC/CCT with target proteins during biosynthesis" XP_037294000.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037301582.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037299568.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_030041378.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825 "Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis" XP_037292364.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_030034963.1 3 MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546 "Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)" XP_037295621.1 11 Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-418594 "G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"PKA activation";"G alpha (i) signalling events" XP_030032435.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_030024742.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_037302368.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037295496.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_030022967.1 6 Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_037296440.1 6 Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-181430 "Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle" XP_037296210.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_030035178.2 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_037299875.1 19 Reactome: R-HSA-3000497;Reactome: R-HSA-8866423;Reactome: R-HSA-3000471;Reactome: R-HSA-8856825;Reactome: R-HSA-5686938;Reactome: R-HSA-3000484;Reactome: R-HSA-8964046;Reactome: R-HSA-975634;Reactome: R-HSA-432142;Reactome: R-HSA-8963888;Reactome: R-HSA-8964038;Reactome: R-HSA-8856828;Reactome: R-HSA-3000480;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-8964041;Reactome: R-HSA-8964026;Reactome: R-HSA-8963901;Reactome: R-HSA-202733 "Scavenging by Class H Receptors";"VLDL assembly";"Scavenging by Class B Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"Scavenging by Class F Receptors";"VLDL clearance";"Retinoid metabolism and transport";"Platelet sensitization by LDL";"Chylomicron assembly";"LDL clearance";"Clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"LDL remodeling";"Chylomicron clearance";"Chylomicron remodeling";"Cell surface interactions at the vascular wall" XP_037297586.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation" XP_030023674.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8875656 "RAB geranylgeranylation";"MET receptor recycling" XP_037294233.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037293934.1 33 Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-2500257 "SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"Viral Messenger RNA Synthesis";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"Mitotic Prometaphase";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"RHO GTPases Activate Formins";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"Resolution of Sister Chromatid Cohesion" XP_037302108.1 15 Reactome: R-HSA-5358749;Reactome: R-HSA-5467333;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-5467337;Reactome: R-HSA-5689896;Reactome: R-HSA-5467340;Reactome: R-HSA-5339716;Reactome: R-HSA-3769402;Reactome: R-HSA-5467348;Reactome: R-HSA-195253;Reactome: R-HSA-111465;Reactome: R-HSA-5358752;Reactome: R-HSA-5358747;Reactome: R-HSA-4641262 "S37 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Ovarian tumor domain proteases";"AXIN missense mutants destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Deactivation of the beta-catenin transactivating complex";"Truncations of AMER1 destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"Apoptotic cleavage of cellular proteins";"T41 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane" XP_037292540.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_037300490.1 11 Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-171007;Reactome: R-HSA-450302;KEGG: 04151+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Relaxin signaling pathway";"p38MAPK events";"activated TAK1 mediates p38 MAPK activation";"PI3K-Akt signaling pathway";"VEGFA-VEGFR2 Pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis" XP_037298556.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_030036709.2 12 MetaCyc: PWY-6142;MetaCyc: PWY-7385;MetaCyc: PWY-5484;KEGG: 00051+4.1.2.13;KEGG: 00030+4.1.2.13;KEGG: 00010+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-1861;Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-1042;KEGG: 00680+4.1.2.13 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gluconeogenesis";"Glycolysis";"Glycolysis IV (plant cytosol)";"Methane metabolism" XP_037297744.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_037300001.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_037292790.1 4 Reactome: R-HSA-1855183;KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841;KEGG: 00053+1.13.99.1 "Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Ascorbate and aldarate metabolism" XP_030025650.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_030031044.2 2 Reactome: R-HSA-389661;Reactome: R-HSA-6783984 "Glyoxylate metabolism and glycine degradation";"Glycine degradation" XP_030019635.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037300990.1 5 Reactome: R-HSA-189085;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855 "Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)" XP_030023516.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_030040700.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037303486.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_030025989.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-5689880 "Mitochondrial calcium ion transport";"Ub-specific processing proteases" XP_037296193.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_030031334.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"RHO GTPases Activate Formins";"Aggrephagy" XP_030020140.2 1 Reactome: R-HSA-8951664 "Neddylation" XP_030029616.2 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_037298413.1 4 MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;Reactome: R-HSA-1660662 "Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism";"Ceramide degradation (generic)";"Glycosphingolipid metabolism" XP_030021269.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030022637.1 4 KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-389661 "Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation" XP_037292764.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_030039251.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037294657.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_030027156.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation" XP_030033649.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_030040932.1 6 KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;MetaCyc: PWY-7900;MetaCyc: PWY-5067;Reactome: R-HSA-189085;KEGG: 00500+3.2.1.1 "Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_037302003.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_030019727.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_030039452.2 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_030023600.1 6 KEGG: 00760+6.3.1.5;MetaCyc: PWY-7761;MetaCyc: PWY-5653;Reactome: R-HSA-196807;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5381 "Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)" XP_030031501.1 14 Reactome: R-HSA-5696397;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-6782135 "Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER" XP_037295332.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037303022.1 1 Reactome: R-HSA-8849175 "Threonine catabolism" XP_030024076.2 7 KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway" XP_030038532.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_037295903.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_030037511.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_030028352.1 15 MetaCyc: PWY-7003;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-8004;KEGG: 00620+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-5723;MetaCyc: PWY-6886;MetaCyc: PWY-7218;KEGG: 00230+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-1042 "Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Entner-Doudoroff pathway I";"Pyruvate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Rubisco shunt";"1-butanol autotrophic biosynthesis (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Purine metabolism";"Glycolysis";"Glycolysis IV (plant cytosol)" XP_030024895.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037298264.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_030040333.1 11 Reactome: R-HSA-6785631;Reactome: R-HSA-1257604;Reactome: R-HSA-1227986;Reactome: R-HSA-9664565;Reactome: R-HSA-1250196;Reactome: R-HSA-5673001;Reactome: R-HSA-1963642;Reactome: R-HSA-8847993;Reactome: R-HSA-8863795;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530 "ERBB2 Regulates Cell Motility";"PIP3 activates AKT signaling";"Signaling by ERBB2";"Signaling by ERBB2 KD Mutants";"SHC1 events in ERBB2 signaling";"RAF/MAP kinase cascade";"PI3K events in ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"Downregulation of ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer" XP_037295062.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_030035722.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_030025411.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030030899.1 4 KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;MetaCyc: PWY-7193 "Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I" XP_037302653.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037300842.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030025770.1 7 Reactome: R-HSA-1221632;Reactome: R-HSA-2559586;Reactome: R-HSA-171306;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110331;Reactome: R-HSA-110330 "Meiotic synapsis";"DNA Damage/Telomere Stress Induced Senescence";"Packaging Of Telomere Ends";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine" XP_037294459.1 13 Reactome: R-HSA-6802952;Reactome: R-HSA-5674135;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;KEGG: 04926+2.7.11.1 "Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Relaxin signaling pathway" XP_037293884.1 9 KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902 "Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Other glycan degradation";"Chitin degradation II (Vibrio)" XP_030026975.1 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" XP_037298231.1 10 Reactome: R-HSA-9648895;Reactome: R-HSA-382556;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72731;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-381042 "Response of EIF2AK1 (HRI) to heme deficiency";"ABC-family proteins mediated transport";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Recycling of eIF2:GDP";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"PERK regulates gene expression" XP_030025083.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037293395.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_030021676.1 1 Reactome: R-HSA-203615 "eNOS activation" XP_030035393.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_030035879.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_030040970.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72695 "Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex" XP_030035644.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037302863.1 4 Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216 "Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization" XP_030027154.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs" XP_037292608.1 3 Reactome: R-HSA-6804760;Reactome: R-HSA-3214841;Reactome: R-HSA-2299718 "Regulation of TP53 Activity through Methylation";"PKMTs methylate histone lysines";"Condensation of Prophase Chromosomes" XP_030026599.1 5 Reactome: R-HSA-9630222;Reactome: R-HSA-9630221;Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110357 "Defective NTHL1 substrate binding";"Defective NTHL1 substrate processing";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1" XP_030033394.1 7 Reactome: R-HSA-114608;Reactome: R-HSA-983170;Reactome: R-HSA-381033;Reactome: R-HSA-381042;Reactome: R-HSA-381183;Reactome: R-HSA-3371453;Reactome: R-HSA-381070 "Platelet degranulation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperones";"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"Regulation of HSF1-mediated heat shock response";"IRE1alpha activates chaperones" XP_030024994.1 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" XP_037295085.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_037303227.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_030036753.1 4 Reactome: R-HSA-8934903;Reactome: R-HSA-1632852;Reactome: R-HSA-5205685;Reactome: R-HSA-936440 "Receptor Mediated Mitophagy";"Macroautophagy";"Pink/Parkin Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling" XP_037300295.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_030025566.2 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_037293366.1 4 Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001 "NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade" XP_037296424.1 6 KEGG: 00630+1.11.1.6;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-6798695;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685 "Glyoxylate and dicarboxylate metabolism";"Tryptophan metabolism";"Peroxisomal protein import";"Neutrophil degranulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species" XP_030039133.2 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_030025316.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_030027602.1 52 Reactome: R-HSA-749476;Reactome: R-HSA-167161;Reactome: R-HSA-76066;Reactome: R-HSA-75953;Reactome: R-HSA-72165;Reactome: R-HSA-167287;Reactome: R-HSA-73980;Reactome: R-HSA-6782135;Reactome: R-HSA-167242;Reactome: R-HSA-73762;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73780;Reactome: R-HSA-113418;Reactome: R-HSA-203927;Reactome: R-HSA-167238;Reactome: R-HSA-72086;Reactome: R-HSA-1834949;Reactome: R-HSA-168325;Reactome: R-HSA-167152;Reactome: R-HSA-6803529;Reactome: R-HSA-75955;Reactome: R-HSA-5617472;Reactome: R-HSA-6796648;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-73776;Reactome: R-HSA-76071;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-72203;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-73772;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-5601884;Reactome: R-HSA-73863;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-72163;Reactome: R-HSA-8851708;Reactome: R-HSA-167162;Reactome: R-HSA-167243;Reactome: R-HSA-76061;Reactome: R-HSA-5250924;Reactome: R-HSA-9018519 "RNA Polymerase III Abortive And Retractive Initiation";"HIV Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Minor Pathway";"HIV elongation arrest and recovery";"RNA Polymerase III Transcription Termination";"Dual incision in TC-NER";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase I Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase III Chain Elongation";"Formation of the Early Elongation Complex";"MicroRNA (miRNA) biogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Capping";"Cytosolic sensors of pathogen-associated DNA";"Viral Messenger RNA Synthesis";"Formation of HIV elongation complex in the absence of HIV Tat";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Processing of Capped Intron-Containing Pre-mRNA";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Promoter Escape";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase I Transcription Termination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Major Pathway";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"B-WICH complex positively regulates rRNA expression";"Estrogen-dependent gene expression" XP_030033214.1 5 Reactome: R-HSA-2894862;Reactome: R-HSA-3214815;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription" XP_030037707.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling" XP_030041341.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_037297682.1 3 Reactome: R-HSA-5689880;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Ub-specific processing proteases";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037303330.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" XP_030020883.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_030041052.2 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_037296550.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_037293435.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway" XP_030038131.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037292226.1 56 Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-8941858 "Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity" XP_037300907.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_030027301.1 1 Reactome: R-HSA-5657655 "MGMT-mediated DNA damage reversal" XP_037294704.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_030035581.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_030023428.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_030035587.2 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" XP_030035551.2 3 MetaCyc: PWY-7159;Reactome: R-HSA-189451;KEGG: 00860+1.3.3.3 "3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism" XP_037301022.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_030029412.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030039169.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_037295301.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037302120.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_037299518.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037296068.1 10 MetaCyc: PWY-8053;MetaCyc: PWY-7587;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-6453;Reactome: R-HSA-1483166 "Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Synthesis of PA" XP_037300704.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_030021223.2 33 Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-68877;Reactome: R-HSA-159231;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-2500257;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-168325;Reactome: R-HSA-3232142;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-4615885 "SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Mitotic Prometaphase";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Resolution of Sister Chromatid Cohesion";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"RHO GTPases Activate Formins";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Viral Messenger RNA Synthesis";"SUMOylation of ubiquitinylation proteins";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA replication proteins" XP_037300204.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_037296141.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030022732.2 1 Reactome: R-HSA-977225 "Amyloid fiber formation" YP_001650751.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_037301044.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037294535.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_037299138.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_037301741.1 13 Reactome: R-HSA-2029485;Reactome: R-HSA-139853;Reactome: R-HSA-112043;Reactome: R-HSA-381676;Reactome: R-HSA-4086398;Reactome: R-HSA-114508;Reactome: R-HSA-2871809;Reactome: R-HSA-5578775;Reactome: R-HSA-5607763;Reactome: R-HSA-5218921;Reactome: R-HSA-1489509;Reactome: R-HSA-983695;Reactome: R-HSA-422356 "Role of phospholipids in phagocytosis";"Elevation of cytosolic Ca2+ levels";"PLC beta mediated events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway";"Effects of PIP2 hydrolysis";"FCERI mediated Ca+2 mobilization";"Ion homeostasis";"CLEC7A (Dectin-1) induces NFAT activation";"VEGFR2 mediated cell proliferation";"DAG and IP3 signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Regulation of insulin secretion" XP_037298897.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037296509.1 9 Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-400206 "Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RORA activates gene expression";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha" XP_030040541.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037303044.1 24 Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-380320 "Cilium Assembly";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"HCMV Early Events";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Kinesins";"Aggrephagy";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes" XP_037292513.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_030039458.2 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_037293725.1 8 Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724 "Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"mTOR signalling";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription" XP_030031282.2 7 MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-7214 "Betanidin degradation";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)" XP_030040879.2 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037302444.1 33 Reactome: R-HSA-8939236;Reactome: R-HSA-167162;Reactome: R-HSA-167160;Reactome: R-HSA-69273;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395;Reactome: R-HSA-73863;Reactome: R-HSA-112382;Reactome: R-HSA-6781827;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-73762;Reactome: R-HSA-69656;Reactome: R-HSA-6782135;Reactome: R-HSA-69231;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-69202 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Cyclin A/B1/B2 associated events during G2/M transition";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Termination";"Formation of RNA Pol II elongation complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Initiation";"Cyclin A:Cdk2-associated events at S phase entry";"Dual incision in TC-NER";"Cyclin D associated events in G1";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"Cyclin E associated events during G1/S transition" XP_037297704.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_030020245.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030030796.2 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_030029315.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_037296429.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_037295103.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_037298345.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030037810.2 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_037294825.1 2 Reactome: R-HSA-6783310;MetaCyc: PWY-7511 "Fanconi Anemia Pathway";"Protein ubiquitination" XP_030029089.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_030034133.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_037297862.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_030020528.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_030030289.1 33 Reactome: R-HSA-8939236;Reactome: R-HSA-69273;Reactome: R-HSA-167160;Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-112382;Reactome: R-HSA-73863;Reactome: R-HSA-5696395;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-73772;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-6782135;Reactome: R-HSA-69656;Reactome: R-HSA-73762;Reactome: R-HSA-76042;Reactome: R-HSA-6781823;Reactome: R-HSA-75953;Reactome: R-HSA-69231;Reactome: R-HSA-69202;Reactome: R-HSA-167161 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Termination";"Formation of Incision Complex in GG-NER";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Dual incision in TC-NER";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation";"Cyclin D associated events in G1";"Cyclin E associated events during G1/S transition";"HIV Transcription Initiation" XP_030020143.2 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037298307.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_037298166.1 5 Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-6783310 "HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Fanconi Anemia Pathway" XP_030026781.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_037299055.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_037298543.1 2 Reactome: R-HSA-164843;Reactome: R-HSA-5693571 "2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)" XP_030037598.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-1632852 "Ub-specific processing proteases";"Macroautophagy" XP_037303237.1 5 Reactome: R-HSA-8866654;Reactome: R-HSA-201722;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695 "E3 ubiquitin ligases ubiquitinate target proteins";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events" XP_030025978.2 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037292363.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_030031106.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030039353.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037292639.1 6 Reactome: R-HSA-6803204;Reactome: R-HSA-6803211;Reactome: R-HSA-6803207;Reactome: R-HSA-139915;Reactome: R-HSA-6803205;Reactome: R-HSA-6804759 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of PUMA and translocation to mitochondria";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Regulation of TP53 Activity through Association with Co-factors" XP_030035271.2 4 KEGG: 00510+2.7.1.108;MetaCyc: PWY-6129;Reactome: R-HSA-446199;Reactome: R-HSA-4755583 "N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"Defective DOLK causes DOLK-CDG (CDG-1m)" XP_030033931.1 3 Reactome: R-HSA-3065676;Reactome: R-HSA-3065678;Reactome: R-HSA-983168 "SUMO is conjugated to E1 (UBA2:SAE1)";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037300411.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_030033365.1 4 Reactome: R-HSA-912631;Reactome: R-HSA-8875656;Reactome: R-HSA-186763;Reactome: R-HSA-8875555 "Regulation of signaling by CBL";"MET receptor recycling";"Downstream signal transduction";"MET activates RAP1 and RAC1" XP_030034163.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037302427.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339 "Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane" XP_030023370.1 5 KEGG: 00520+3.5.99.6;Reactome: R-HSA-70171;MetaCyc: PWY-5514;MetaCyc: PWY-6906;MetaCyc: PWY-6855 "Amino sugar and nucleotide sugar metabolism";"Glycolysis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation";"Chitin degradation I (archaea)" XP_030023179.2 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_030040723.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_030023247.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-1912420 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi" XP_037301916.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_037299259.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_030027293.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_030027068.2 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_030036288.2 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_030033357.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_030021942.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_030023951.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_030023071.2 1 Reactome: R-HSA-156581 "Methylation" XP_030019778.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_030020988.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037298970.1 7 Reactome: R-HSA-351202;KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00480+2.5.1.22;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.16 "Metabolism of polyamines";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism" XP_030041221.1 11 Reactome: R-HSA-9013508;Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-72163;Reactome: R-HSA-1912408;Reactome: R-HSA-2173796;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695 "NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"mRNA Splicing - Major Pathway";"Pre-NOTCH Transcription and Translation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription" XP_030028921.2 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_030025902.1 33 Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-6782135;Reactome: R-HSA-73762;Reactome: R-HSA-69656;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-69231;Reactome: R-HSA-69202;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-73863;Reactome: R-HSA-5696395;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-73772;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-8939236;Reactome: R-HSA-69273;Reactome: R-HSA-167160;Reactome: R-HSA-167162;Reactome: R-HSA-6782210 "RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Dual incision in TC-NER";"RNA Polymerase I Transcription Initiation";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Cyclin D associated events in G1";"Cyclin E associated events during G1/S transition";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Termination";"Formation of Incision Complex in GG-NER";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_030020370.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_030028656.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037293625.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037296246.1 8 Reactome: R-HSA-111464;Reactome: R-HSA-111463;Reactome: R-HSA-8953750;Reactome: R-HSA-6798695;Reactome: R-HSA-9627069;Reactome: R-HSA-6803207;Reactome: R-HSA-111458;Reactome: R-HSA-111459 "SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC (DIABLO) binds to IAPs";"Transcriptional Regulation by E2F6";"Neutrophil degranulation";"Regulation of the apoptosome activity";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage" XP_037300506.1 6 Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649 "L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation" XP_030029836.2 2 Reactome: R-HSA-163841;KEGG: 00900+2.1.1.100 "Gamma carboxylation, hypusine formation and arylsulfatase activation";"Terpenoid backbone biosynthesis" XP_037295754.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037301602.1 6 Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-72163;Reactome: R-HSA-111367;Reactome: R-HSA-191859 "mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"snRNP Assembly" XP_037301123.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037293412.1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway" XP_030034036.2 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037299581.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_030024846.1 4 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-8866654 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins" XP_037292410.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_030023570.2 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" XP_037297694.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_037303497.1 5 Reactome: R-HSA-1632852;Reactome: R-HSA-8854214;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-165181 "Macroautophagy";"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB" XP_037297951.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_030027936.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_030025053.2 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_030035179.2 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_030022150.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_037292750.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037299675.1 2 Reactome: R-HSA-6807004;Reactome: R-HSA-877312 "Negative regulation of MET activity";"Regulation of IFNG signaling" XP_030019715.1 10 MetaCyc: PWY-4041;MetaCyc: PWY-7112;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-7559;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-5826 "Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis" XP_030021593.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_030031129.2 10 KEGG: 00051+5.3.1.1;KEGG: 00710+5.3.1.1;MetaCyc: PWY-1042;KEGG: 00010+5.3.1.1;Reactome: R-HSA-70171;Reactome: R-HSA-70263;MetaCyc: PWY-7003;KEGG: 00562+5.3.1.1;MetaCyc: PWY-5484;MetaCyc: PWY-6142 "Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Glycolysis";"Gluconeogenesis";"Glycerol degradation to butanol";"Inositol phosphate metabolism";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_037302095.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037300996.1 5 MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822 "Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)" XP_037299070.1 3 MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740 "Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors" XP_030029112.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037299946.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_030020996.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_030041001.2 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_030034982.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030026570.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_030021085.2 5 Reactome: R-HSA-9627069;KEGG: 00270+4.2.1.109;MetaCyc: PWY-4361;Reactome: R-HSA-111458;Reactome: R-HSA-1237112 "Regulation of the apoptosome activity";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Formation of apoptosome";"Methionine salvage pathway" XP_037301468.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_030031310.2 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_037303282.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037296758.1 2 Reactome: R-HSA-174403;Reactome: R-HSA-5578999 "Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)" XP_030026017.1 1 Reactome: R-HSA-6806664 "Metabolism of vitamin K" XP_030040918.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037301969.1 5 Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73762 "RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation" XP_037296807.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037300459.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037296064.1 10 MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-8053;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-8051 "CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I" XP_030022313.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030034342.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825 "Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis" XP_037294095.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_030025415.2 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_030019729.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_037292743.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030040275.2 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_037292239.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_037295052.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_030020590.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037302252.1 16 Reactome: R-HSA-1236394;Reactome: R-HSA-1250342;Reactome: R-HSA-8863795;Reactome: R-HSA-1963640;Reactome: R-HSA-1257604;Reactome: R-HSA-1250196;Reactome: R-HSA-8847993;Reactome: R-HSA-1963642;Reactome: R-HSA-1251985;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-6785631;Reactome: R-HSA-1250347;Reactome: R-HSA-1227986;Reactome: R-HSA-9664565 "Signaling by ERBB4";"PI3K events in ERBB4 signaling";"Downregulation of ERBB2 signaling";"GRB2 events in ERBB2 signaling";"PIP3 activates AKT signaling";"SHC1 events in ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"PI3K events in ERBB2 signaling";"Nuclear signaling by ERBB4";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Regulates Cell Motility";"SHC1 events in ERBB4 signaling";"Signaling by ERBB2";"Signaling by ERBB2 KD Mutants" XP_037297236.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_030026725.2 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_037302009.1 5 Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-1655829 "Cargo concentration in the ER";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_037300843.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030041039.2 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_037303048.1 6 Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426 "Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)" XP_037296706.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_037302492.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_030033184.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037298639.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_030036489.2 3 Reactome: R-HSA-162658;Reactome: R-HSA-6807878;Reactome: R-HSA-204005 "Golgi Cisternae Pericentriolar Stack Reorganization";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport" XP_037296080.1 3 Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355 "Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction" XP_030025577.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037300017.1 1 Reactome: R-HSA-3000171 "Non-integrin membrane-ECM interactions" XP_037292649.1 7 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection" XP_030024845.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037299466.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037300494.1 14 Reactome: R-HSA-1483166;MetaCyc: PWY-7782;MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-6453;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-7417;MetaCyc: PWY-8053 "Synthesis of PA";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II" XP_030026553.2 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_030040662.2 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_037297640.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_030040261.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_037300126.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_030027020.2 14 Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-113418 "Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex" XP_037293940.1 4 Reactome: R-HSA-937039;Reactome: R-HSA-975144;MetaCyc: PWY-7511;Reactome: R-HSA-9020702 "IRAK1 recruits IKK complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Protein ubiquitination";"Interleukin-1 signaling" XP_030032305.1 10 KEGG: 00650+2.3.3.10;MetaCyc: PWY-922;KEGG: 00280+2.3.3.10;MetaCyc: PWY-7391;MetaCyc: PWY-7524;MetaCyc: PWY-7571;KEGG: 00072+2.3.3.10;MetaCyc: PWY-6174;KEGG: 00900+2.3.3.10;Reactome: R-HSA-1989781 "Butanoate metabolism";"Mevalonate pathway I";"Valine, leucine and isoleucine degradation";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Ferrichrome A biosynthesis";"Synthesis and degradation of ketone bodies";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"PPARA activates gene expression" XP_030033177.2 5 Reactome: R-HSA-5689880;MetaCyc: PWY-7511;Reactome: R-HSA-201681;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257 "Ub-specific processing proteases";"Protein ubiquitination";"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"Degradation of AXIN" XP_030027123.2 8 KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "Human cytomegalovirus infection";"Thermogenesis";"Activation of RAC1";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway" XP_037298257.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_030027499.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_030025795.1 8 Reactome: R-HSA-442720;Reactome: R-HSA-5610787;Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-180024;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-164378 "CREB1 phosphorylation through the activation of Adenylate Cyclase";"Hedgehog 'off' state";"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling" XP_030039406.1 6 Reactome: R-HSA-191859;Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72165 "snRNP Assembly";"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway" XP_037298805.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_037293704.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_030026834.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030020655.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_037301000.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_037294783.1 1 KEGG: 00270+2.1.1.37 "Cysteine and methionine metabolism" XP_037293374.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-375165 "COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth" XP_030034202.2 3 Reactome: R-HSA-1810476;Reactome: R-HSA-445989;Reactome: R-HSA-933542 "RIP-mediated NFkB activation via ZBP1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6 mediated NF-kB activation" XP_037297763.1 4 MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943 "Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_037294709.1 13 Reactome: R-HSA-139853;Reactome: R-HSA-2029485;Reactome: R-HSA-112043;Reactome: R-HSA-381676;Reactome: R-HSA-4086398;Reactome: R-HSA-114508;Reactome: R-HSA-2871809;Reactome: R-HSA-5578775;Reactome: R-HSA-5607763;Reactome: R-HSA-5218921;Reactome: R-HSA-1489509;Reactome: R-HSA-983695;Reactome: R-HSA-422356 "Elevation of cytosolic Ca2+ levels";"Role of phospholipids in phagocytosis";"PLC beta mediated events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway";"Effects of PIP2 hydrolysis";"FCERI mediated Ca+2 mobilization";"Ion homeostasis";"CLEC7A (Dectin-1) induces NFAT activation";"VEGFR2 mediated cell proliferation";"DAG and IP3 signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Regulation of insulin secretion" XP_037293148.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_030032288.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118 "SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors" XP_030029265.2 2 Reactome: R-HSA-3214815;Reactome: R-HSA-427413 "HDACs deacetylate histones";"NoRC negatively regulates rRNA expression" XP_030029706.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_030024048.1 26 Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-389960;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-389977;Reactome: R-HSA-380320;Reactome: R-HSA-8852276 "Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"HCMV Early Events";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Formation of tubulin folding intermediates by CCT/TriC";"Recycling pathway of L1";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Post-chaperonin tubulin folding pathway";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint" XP_030035650.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037292420.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-936837 "Neutrophil degranulation";"Ion transport by P-type ATPases" XP_030022619.1 16 KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5538;KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5749;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.5;KEGG: 00640+6.2.1.4;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-5913;KEGG: 00020+6.2.1.4;MetaCyc: PWY-5690;MetaCyc: PWY-5537 "C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"Pyruvate fermentation to acetate VI";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Itaconate degradation";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"Propanoate metabolism";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate V" XP_037296088.1 8 Reactome: R-HSA-6796648;Reactome: R-HSA-9633012;Reactome: R-HSA-8943724;Reactome: R-HSA-450341;Reactome: R-HSA-3214847;Reactome: R-HSA-9018519;Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "TP53 Regulates Transcription of DNA Repair Genes";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of PTEN gene transcription";"Activation of the AP-1 family of transcription factors";"HATs acetylate histones";"Estrogen-dependent gene expression";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_030019749.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037300181.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037298713.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037298276.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_030040119.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037303635.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_030040212.2 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_030020695.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_030035890.1 7 Reactome: R-HSA-140837;Reactome: R-HSA-375276;Reactome: R-HSA-8957275;Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-381426;Reactome: R-HSA-114608 "Intrinsic Pathway of Fibrin Clot Formation";"Peptide ligand-binding receptors";"Post-translational protein phosphorylation";"G alpha (q) signalling events";"G alpha (i) signalling events";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Platelet degranulation" XP_030023244.1 4 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases" XP_030022212.1 25 Reactome: R-HSA-416476;Reactome: R-HSA-202040;Reactome: R-HSA-432040;Reactome: R-HSA-428930;Reactome: R-HSA-500657;Reactome: R-HSA-381771;Reactome: R-HSA-420092;Reactome: R-HSA-418597;Reactome: R-HSA-8964616;Reactome: R-HSA-4086398;Reactome: R-HSA-381676;Reactome: R-HSA-400042;Reactome: R-HSA-6814122;Reactome: R-HSA-392170;Reactome: R-HSA-416482;Reactome: R-HSA-418594;Reactome: R-HSA-456926;Reactome: R-HSA-418217;Reactome: R-HSA-418592;Reactome: R-HSA-163359;Reactome: R-HSA-392851;Reactome: R-HSA-392451;Reactome: R-HSA-9009391;Reactome: R-HSA-418555;Reactome: R-HSA-8964315 "G alpha (q) signalling events";"G-protein activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thromboxane signalling through TP receptor";"Presynaptic function of Kainate receptors";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Glucagon-type ligand receptors";"G alpha (z) signalling events";"G beta:gamma signalling through CDC42";"Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Adrenaline,noradrenaline inhibits insulin secretion";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"ADP signalling through P2Y purinoceptor 12";"G alpha (12/13) signalling events";"G alpha (i) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 1";"Glucagon signaling in metabolic regulation";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through PI3Kgamma";"Extra-nuclear estrogen signaling";"G alpha (s) signalling events";"G beta:gamma signalling through BTK" XP_030020075.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-182971 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation" XP_030021846.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037298261.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_037293157.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_030036475.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8869496 "Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" XP_037297275.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_030033630.1 3 MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217 "Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage" XP_030033990.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030031189.2 3 Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2 "Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism" XP_030023785.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_030041355.2 8 Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-6798695;Reactome: R-HSA-380270;Reactome: R-HSA-380259 "AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Neutrophil degranulation";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes" XP_030024222.2 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_030032371.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030036317.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_030041091.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_030020096.2 2 Reactome: R-HSA-975957;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_037292993.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_030025982.1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_030022508.2 8 Reactome: R-HSA-8953750;Reactome: R-HSA-6798695;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-6803207;Reactome: R-HSA-9627069 "Transcriptional Regulation by E2F6";"Neutrophil degranulation";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of the apoptosome activity" XP_037296292.1 5 Reactome: R-HSA-9627069;KEGG: 00270+4.2.1.109;MetaCyc: PWY-4361;Reactome: R-HSA-1237112;Reactome: R-HSA-111458 "Regulation of the apoptosome activity";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"Formation of apoptosome" XP_037298824.1 12 MetaCyc: PWY-5871;MetaCyc: PWY-5873;MetaCyc: PWY-7230;MetaCyc: PWY-7233;MetaCyc: PWY-5855;MetaCyc: PWY-5857;MetaCyc: PWY-5870;Reactome: R-HSA-2142789;MetaCyc: PWY-6708;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5872;MetaCyc: PWY-5856 "Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)" XP_030026838.2 5 KEGG: 00281+4.1.3.4;KEGG: 00650+4.1.3.4;KEGG: 00072+4.1.3.4;KEGG: 00280+4.1.3.4;MetaCyc: PWY-5074 "Geraniol degradation";"Butanoate metabolism";"Synthesis and degradation of ketone bodies";"Valine, leucine and isoleucine degradation";"Mevalonate degradation" XP_030027230.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_037295189.1 4 Reactome: R-HSA-6807047;KEGG: 00100+1.3.1.72;Reactome: R-HSA-6807062;MetaCyc: PWY-8026 "Cholesterol biosynthesis via desmosterol";"Steroid biosynthesis";"Cholesterol biosynthesis via lathosterol";"Sterol biosynthesis (methylotrophs)" XP_037302537.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_037293656.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037297867.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_037295651.1 7 MetaCyc: PWY-7791;MetaCyc: PWY-5697;MetaCyc: PWY-7790;KEGG: 00230+3.5.2.5;KEGG: 00240+3.5.2.3;MetaCyc: PWY-5686;MetaCyc: PWY-5698 "UMP biosynthesis III";"Allantoin degradation to ureidoglycolate I (urea producing)";"UMP biosynthesis II";"Purine metabolism";"Pyrimidine metabolism";"UMP biosynthesis I";"Allantoin degradation to ureidoglycolate II (ammonia producing)" XP_030034100.1 57 Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-69601;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-6798695;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5362768 "Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"Neutrophil degranulation";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_030021437.1 3 Reactome: R-HSA-4608870;Reactome: R-HSA-373080;Reactome: R-HSA-4086400 "Asymmetric localization of PCP proteins";"Class B/2 (Secretin family receptors)";"PCP/CE pathway" XP_030020283.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_030029798.2 57 Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-69601;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-4641258;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091 "ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Degradation of DVL";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells" XP_037301269.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030039585.1 8 KEGG: 00230+3.5.4.4;MetaCyc: PWY-6611;Reactome: R-HSA-74217;Reactome: R-HSA-5683826;MetaCyc: PWY-6609;Reactome: R-HSA-6798695;MetaCyc: PWY-7179;MetaCyc: PWY-7179-1 "Purine metabolism";"Adenine and adenosine salvage V";"Purine salvage";"Surfactant metabolism";"Adenine and adenosine salvage III";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I";"Purine deoxyribonucleosides degradation II" XP_037302861.1 1 Reactome: R-HSA-1614603 "Cysteine formation from homocysteine" XP_030036619.1 10 Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-2565942 "AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition" XP_037298026.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_030029006.1 3 Reactome: R-HSA-6784531;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470 "tRNA processing in the nucleus";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion" XP_037295841.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037301629.1 5 Reactome: R-HSA-196807;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-7269 "Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_030032050.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037294304.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_030020269.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037292682.1 3 KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693 "Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism" XP_037295662.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_030032280.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_030041101.2 10 Reactome: R-HSA-3214847;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-201722;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5689880 "HATs acetylate histones";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Formation of the beta-catenin:TCF transactivating complex";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Ub-specific processing proteases" XP_037294557.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_037298571.1 20 KEGG: 00592+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7726;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7340;MetaCyc: PWY-7007;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7338;MetaCyc: PWY-7858;MetaCyc: PWY-7854;MetaCyc: PWY-7288;MetaCyc: PWY-7291;MetaCyc: PWY-735;KEGG: 00410+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-7574 "alpha-Linolenic acid metabolism";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"6-gingerol analog biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"beta-Alanine metabolism";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoyl-coa degradation II" XP_030035454.2 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_037296712.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037295215.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037292213.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_030027804.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030021087.2 10 MetaCyc: PWY-6369;MetaCyc: PWY-6554;MetaCyc: PWY-6361;Reactome: R-HSA-1855191;MetaCyc: PWY-6372;MetaCyc: PWY-6362;KEGG: 00562+2.7.1.158;MetaCyc: PWY-4661;KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855167 "Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol" XP_037296043.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_037301416.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_030024248.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_037299389.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_037295734.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_030020203.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030040681.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037298358.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_030026681.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_030027127.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_037302972.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_037298168.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_030031791.2 17 Reactome: R-HSA-113418;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167290;Reactome: R-HSA-112382;KEGG: 04658+3.1.3.16;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-167246;Reactome: R-HSA-167287;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167238 "Formation of the Early Elongation Complex";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Th1 and Th2 cell differentiation";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"T cell receptor signaling pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation" XP_030032529.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_037296434.1 6 Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-181429 "Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_030029229.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037298638.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_030029325.1 9 MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-8004;MetaCyc: PWY-7003;KEGG: 00010+1.2.1.12;Reactome: R-HSA-70171;Reactome: R-HSA-70263;KEGG: 00710+1.2.1.12;MetaCyc: PWY-1042 "Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Glycolysis";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)" XP_030032382.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_037303360.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030027333.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72764 "Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Eukaryotic Translation Termination" XP_037298350.1 3 Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events" XP_030027796.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030022177.2 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_030032324.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037300251.1 18 KEGG: 00220+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00330+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00350+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00270+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-6642;MetaCyc: PWY-6643;MetaCyc: PWY-7115;KEGG: 00950+2.6.1.1 "Arginine biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Arginine and proline metabolism";"Phenylalanine metabolism";"Novobiocin biosynthesis";"Sulfolactate degradation III";"Tyrosine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Alanine, aspartate and glutamate metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Cysteine and methionine metabolism";"Carbon fixation in photosynthetic organisms";"Anaerobic energy metabolism (invertebrates, cytosol)";"(R)-cysteate degradation";"Coenzyme M biosynthesis II";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Isoquinoline alkaloid biosynthesis" XP_030040084.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_037297948.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_030033822.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_030036756.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_030029308.1 5 MetaCyc: PWY-7268;MetaCyc: PWY-7269;MetaCyc: PWY-5083;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism" XP_030027149.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_030025249.2 2 Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_037302839.1 9 Reactome: R-HSA-2173789;Reactome: R-HSA-2173788;Reactome: R-HSA-2173791;Reactome: R-HSA-3645790;Reactome: R-HSA-3304356;Reactome: R-HSA-3656535;Reactome: R-HSA-5689603;Reactome: R-HSA-3642279;Reactome: R-HSA-3656532 "TGF-beta receptor signaling activates SMADs";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR2 Kinase Domain Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"UCH proteinases";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR1 KD Mutants in Cancer" XP_030023639.2 12 KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-6708;MetaCyc: PWY-5856;MetaCyc: PWY-5872;MetaCyc: PWY-5873;MetaCyc: PWY-7230;MetaCyc: PWY-7233;MetaCyc: PWY-5871;MetaCyc: PWY-5870;Reactome: R-HSA-2142789;MetaCyc: PWY-5857;MetaCyc: PWY-5855 "Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)" XP_030024154.2 5 KEGG: 00620+4.1.1.32;Reactome: R-HSA-70263;MetaCyc: PWY-7383;KEGG: 00020+4.1.1.32;KEGG: 00010+4.1.1.32 "Pyruvate metabolism";"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis" XP_037302745.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_030029725.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" XP_030024492.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-5689880 "Translesion Synthesis by POLH";"Ub-specific processing proteases" XP_030034347.2 4 MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48 "Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine metabolism" XP_037293920.1 3 Reactome: R-HSA-425561;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Sodium/Calcium exchangers";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_030026849.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037296925.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_037298693.1 7 MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-5461 "Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation" XP_037302845.1 3 KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3;Reactome: R-HSA-977347 "Methane metabolism";"Glycine, serine and threonine metabolism";"Serine biosynthesis" XP_030026494.1 13 MetaCyc: PWY-7721;MetaCyc: PWY-7659;MetaCyc: PWY-6859;MetaCyc: PWY-7709;MetaCyc: PWY-6383;MetaCyc: PWY-7736;MetaCyc: PWY-5122;MetaCyc: PWY-5123;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7102;MetaCyc: PWY-7141;MetaCyc: PWY-7410;MetaCyc: PWY-7182 "Methyl phomopsenoate biosynthesis";"Viridicatumtoxin biosynthesis";"All-trans-farnesol biosynthesis";"(3R)-linalool biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Stellatic acid biosynthesis";"Geranyl diphosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Terpenoid backbone biosynthesis";"Bisabolene biosynthesis (engineered)";"(3S)-linalool biosynthesis";"Ipsdienol biosynthesis";"Linalool biosynthesis I" XP_037292920.1 5 Reactome: R-HSA-3270619;Reactome: R-HSA-1834941;Reactome: R-HSA-6798695;Reactome: R-HSA-3249367;Reactome: R-HSA-3134975 "IRF3-mediated induction of type I IFN";"STING mediated induction of host immune responses";"Neutrophil degranulation";"STAT6-mediated induction of chemokines";"Regulation of innate immune responses to cytosolic DNA" XP_030033966.2 5 MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6527 "D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactose detoxification";"Stachyose degradation" XP_030030371.1 8 Reactome: R-HSA-6798695;MetaCyc: PWY-6609;MetaCyc: PWY-7179;MetaCyc: PWY-7179-1;KEGG: 00230+3.5.4.4;Reactome: R-HSA-5683826;MetaCyc: PWY-6611;Reactome: R-HSA-74217 "Neutrophil degranulation";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation I";"Purine deoxyribonucleosides degradation II";"Purine metabolism";"Surfactant metabolism";"Adenine and adenosine salvage V";"Purine salvage" XP_030030829.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_030034940.2 3 MetaCyc: PWY-2161B;Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9 "Glutamate removal from folates";"Neutrophil degranulation";"Folate biosynthesis" XP_030022597.1 8 KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Activation of RAC1";"Thermogenesis";"Human cytomegalovirus infection" XP_030024813.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_037293613.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_037302345.1 6 Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-181430 "Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle" XP_037300530.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_030028188.2 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037301380.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_030036137.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_030035850.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_030026650.1 3 Reactome: R-HSA-71336;KEGG: 00030+1.1.1.44;KEGG: 00480+1.1.1.44 "Pentose phosphate pathway";"Pentose phosphate pathway";"Glutathione metabolism" XP_037298563.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_030030023.2 4 Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-68884;Reactome: R-HSA-6811434 "Kinesins";"MHC class II antigen presentation";"Mitotic Telophase/Cytokinesis";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037302117.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037302089.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_030028137.1 14 MetaCyc: PWY-5057;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5078;MetaCyc: PWY-5108;MetaCyc: PWY-7767;MetaCyc: PWY-5076;Reactome: R-HSA-70895;KEGG: 00770+2.6.1.42;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5103;MetaCyc: PWY-5101;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5104;KEGG: 00280+2.6.1.42 "L-valine degradation II";"Glucosinolate biosynthesis";"L-isoleucine degradation II";"L-isoleucine biosynthesis V";"L-leucine degradation IV (Stickland reaction)";"L-leucine degradation III";"Branched-chain amino acid catabolism";"Pantothenate and CoA biosynthesis";"Cysteine and methionine metabolism";"L-isoleucine biosynthesis III";"L-isoleucine biosynthesis II";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis IV";"Valine, leucine and isoleucine degradation" XP_037298451.1 6 Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-5620922;Reactome: R-HSA-389957 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC" XP_030024606.2 9 MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902 "Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Chitin degradation II (Vibrio)" XP_030035871.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_030020764.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_037302869.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037300002.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_030024559.2 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_037302821.1 3 Reactome: R-HSA-383280;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "Nuclear Receptor transcription pathway";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_037293919.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers" XP_030026976.1 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" XP_030035031.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_030023486.2 4 Reactome: R-HSA-1799339;Reactome: R-HSA-6798695;Reactome: R-HSA-879415;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation";"Advanced glycosylation endproduct receptor signaling";"Asparagine N-linked glycosylation" XP_030029425.2 18 Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-166208;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-6790901;Reactome: R-HSA-192823 "Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"mTORC1-mediated signalling";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"rRNA modification in the nucleus and cytosol";"Viral mRNA Translation" XP_030025794.1 8 Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-442720;Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-180024 "PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events" XP_037294266.1 4 Reactome: R-HSA-210991;Reactome: R-HSA-5660862;Reactome: R-HSA-71240;Reactome: R-HSA-352230 "Basigin interactions";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism";"Amino acid transport across the plasma membrane" XP_037293697.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_030023571.2 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_030035346.1 3 Reactome: R-HSA-6794361;Reactome: R-HSA-264870;Reactome: R-HSA-6798695 "Neurexins and neuroligins";"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation" XP_030027148.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_037302386.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037293645.1 4 Reactome: R-HSA-5689880;Reactome: R-HSA-418594;Reactome: R-HSA-4641257;Reactome: R-HSA-201681 "Ub-specific processing proteases";"G alpha (i) signalling events";"Degradation of AXIN";"TCF dependent signaling in response to WNT" XP_030040627.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_030032302.1 12 MetaCyc: PWY-5857;MetaCyc: PWY-5855;MetaCyc: PWY-5870;Reactome: R-HSA-2142789;MetaCyc: PWY-5871;MetaCyc: PWY-5873;MetaCyc: PWY-7230;MetaCyc: PWY-7233;MetaCyc: PWY-5872;MetaCyc: PWY-5856;MetaCyc: PWY-6708;KEGG: 00130+1.14.99.60 "Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_030034798.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037302633.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_030035268.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_030037186.1 6 Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-6798695 "ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Neutrophil degranulation" XP_030025164.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_030028613.1 7 Reactome: R-HSA-1221632;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9018519;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-3108214 "Meiotic synapsis";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Estrogen-dependent gene expression";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins" XP_030031669.1 1 Reactome: R-HSA-5617472 "Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_030019581.2 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_037293874.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_037303573.1 12 Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-3214847;Reactome: R-HSA-5250924;Reactome: R-HSA-9013695;Reactome: R-HSA-2122947;Reactome: R-HSA-73762;Reactome: R-HSA-2894862;Reactome: R-HSA-210744 "Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HATs acetylate histones";"B-WICH complex positively regulates rRNA expression";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"RNA Polymerase I Transcription Initiation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells" XP_030032907.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_030025536.1 4 Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin" XP_037299463.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7725 "Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_030020515.2 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037299893.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037294558.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_037295347.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_030030037.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_030030518.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037297092.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_030041168.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037301100.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" YP_001650757.1 7 MetaCyc: PWY-3781;KEGG: 00190+7.1.1.2;Reactome: R-HSA-6799198;Reactome: R-HSA-611105;MetaCyc: PWY-4302;MetaCyc: PWY-5083;MetaCyc: PWY-6692 "Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"Complex I biogenesis";"Respiratory electron transport";"Aerobic respiration III (alternative oxidase pathway)";"NAD/NADH phosphorylation and dephosphorylation";"Fe(II) oxidation" XP_037303121.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_030022148.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_030024538.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030023953.2 12 Reactome: R-HSA-156827;Reactome: R-HSA-166208;Reactome: R-HSA-450408;Reactome: R-HSA-72662;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-429947;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-1169408;Reactome: R-HSA-975956;Reactome: R-HSA-975957 "L13a-mediated translational silencing of Ceruloplasmin expression";"mTORC1-mediated signalling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Deadenylation of mRNA";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ISG15 antiviral mechanism";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_030021857.1 27 Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-4570464 "Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins" XP_030023528.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_030023656.2 5 Reactome: R-HSA-432720;KEGG: 00531+3.1.6.14;Reactome: R-HSA-2022857;Reactome: R-HSA-6798695;Reactome: R-HSA-2206305 "Lysosome Vesicle Biogenesis";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Neutrophil degranulation";"MPS IIID - Sanfilippo syndrome D" XP_030039520.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-75953 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation" XP_037297387.1 5 MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922 "Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_030028406.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_037300526.1 9 Reactome: R-HSA-416482;Reactome: R-HSA-5218920;Reactome: R-HSA-2029482;Reactome: R-HSA-193648;Reactome: R-HSA-4420097;Reactome: R-HSA-114604;Reactome: R-HSA-2871809;Reactome: R-HSA-2871796;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"VEGFR2 mediated vascular permeability";"Regulation of actin dynamics for phagocytic cup formation";"NRAGE signals death through JNK";"VEGFA-VEGFR2 Pathway";"GPVI-mediated activation cascade";"FCERI mediated Ca+2 mobilization";"FCERI mediated MAPK activation";"Rho GTPase cycle" XP_037293609.1 2 Reactome: R-HSA-5658442;Reactome: R-HSA-6802953 "Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants" XP_030031219.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037292975.1 5 MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism" XP_037294442.1 8 Reactome: R-HSA-606279;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-6783310 "Deposition of new CENPA-containing nucleosomes at the centromere";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Fanconi Anemia Pathway" XP_030040310.1 13 Reactome: R-HSA-202433;MetaCyc: PWY-6351;Reactome: R-HSA-2424491;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;Reactome: R-HSA-2029485;MetaCyc: PWY-8052;Reactome: R-HSA-9027277;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;Reactome: R-HSA-2871809;Reactome: R-HSA-2871796 "Generation of second messenger molecules";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"DAP12 signaling";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Role of phospholipids in phagocytosis";"2-arachidonoylglycerol biosynthesis";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"FCERI mediated Ca+2 mobilization";"FCERI mediated MAPK activation" XP_030037826.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_037300359.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_030024992.1 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" XP_030026618.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_030036720.2 5 KEGG: 00270+6.3.2.3;Reactome: R-HSA-174403;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006 "Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)" XP_037299068.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_030033050.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_030023967.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_037297401.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664 "Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation" XP_030037291.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030022232.1 5 MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317 "Stachyose degradation";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)" XP_030025246.2 2 Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_037293343.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_030032162.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_030030176.1 5 MetaCyc: PWY-6855;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;Reactome: R-HSA-189085 "Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate" XP_037296644.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" XP_037292882.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_030020645.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_030039880.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_030031069.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_037294476.1 2 MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24 "Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis" XP_037296063.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_037294948.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_037295780.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_037293729.1 8 Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897 "mTOR signalling";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes" XP_037300372.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_037297358.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_030021877.2 3 Reactome: R-HSA-9634638;Reactome: R-HSA-525793;Reactome: R-HSA-5663220 "Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis";"RHO GTPases Activate Formins" XP_030023203.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" XP_037292939.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_037295909.1 8 KEGG: 00900+1.1.1.34;MetaCyc: PWY-7391;MetaCyc: PWY-7524;Reactome: R-HSA-2426168;MetaCyc: PWY-922;Reactome: R-HSA-1989781;MetaCyc: PWY-6174;Reactome: R-HSA-191273 "Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"PPARA activates gene expression";"Mevalonate pathway II (archaea)";"Cholesterol biosynthesis" XP_030036701.2 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_030041073.2 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_037294542.1 8 Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-5689880 "Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Ub-specific processing proteases" XP_030025211.2 3 Reactome: R-HSA-1614558;Reactome: R-HSA-1614603;Reactome: R-HSA-2408508 "Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_037294320.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_030040628.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_030034113.2 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_030031459.1 15 Reactome: R-HSA-9665233;Reactome: R-HSA-9652282;Reactome: R-HSA-1227986;Reactome: R-HSA-9665244;Reactome: R-HSA-9665250;Reactome: R-HSA-9664565;Reactome: R-HSA-9665249;Reactome: R-HSA-1236382;Reactome: R-HSA-9665245;Reactome: R-HSA-5637810;Reactome: R-HSA-9665247;Reactome: R-HSA-9665251;Reactome: R-HSA-9665246;Reactome: R-HSA-9634285;Reactome: R-HSA-8863795 "Resistance of ERBB2 KD mutants to trastuzumab";"Drug-mediated inhibition of ERBB2 signaling";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to sapitinib";"Resistance of ERBB2 KD mutants to AEE788";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to afatinib";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Resistance of ERBB2 KD mutants to tesevatinib";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to osimertinib";"Resistance of ERBB2 KD mutants to lapatinib";"Resistance of ERBB2 KD mutants to neratinib";"Constitutive Signaling by Overexpressed ERBB2";"Downregulation of ERBB2 signaling" XP_030036319.2 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_037299170.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_030027918.1 26 Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-389960;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-389977;Reactome: R-HSA-380320;Reactome: R-HSA-8852276 "Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"HCMV Early Events";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Formation of tubulin folding intermediates by CCT/TriC";"Recycling pathway of L1";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Post-chaperonin tubulin folding pathway";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint" XP_030035451.2 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_037300646.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-202433 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Generation of second messenger molecules" XP_037293513.1 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_030036407.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030041114.1 2 Reactome: R-HSA-5601884;Reactome: R-HSA-1221632 "PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis" XP_030035694.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_030019797.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-1268020 "Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import" XP_030027241.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_037295623.1 11 KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-418555 "Purine metabolism";"PKA activation";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"G alpha (s) signalling events" XP_030025930.1 12 KEGG: 00520+2.7.7.9;MetaCyc: PWY-7817;Reactome: R-HSA-3322077;KEGG: 00052+2.7.7.9;MetaCyc: PWY-6527;MetaCyc: PWY-7343;KEGG: 00561+2.7.7.9;KEGG: 00040+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-7238;MetaCyc: PWY-3801;KEGG: 00500+2.7.7.9 "Amino sugar and nucleotide sugar metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycogen synthesis";"Galactose metabolism";"Stachyose degradation";"UDP-alpha-D-glucose biosynthesis I";"Glycerolipid metabolism";"Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate";"Sucrose biosynthesis II";"Sucrose degradation II (sucrose synthase)";"Starch and sucrose metabolism" XP_037300360.1 27 Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214 "Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins" XP_037296736.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_030026574.2 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037303291.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_030040696.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030040152.2 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037300708.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_030025684.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis" XP_037299459.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_030033710.2 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" XP_037299736.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_030034783.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689896 "Ub-specific processing proteases";"Ovarian tumor domain proteases" XP_037300254.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_030020984.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_030035163.1 2 KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23 "Pyrimidine metabolism";"Drug metabolism - other enzymes" XP_030019803.1 57 Reactome: R-HSA-1234176;Reactome: R-HSA-8939236;Reactome: R-HSA-8939902;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-180585;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-187577 "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX2 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"UCH proteinases";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21" XP_037295897.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030035231.2 1 KEGG: 00970+6.1.1.19 "Aminoacyl-tRNA biosynthesis" XP_037301764.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_030019680.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_030031472.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037300699.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9633012 "Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_030037904.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037298080.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_030035272.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_037293968.1 4 MetaCyc: PWY-6823;KEGG: 00790+2.8.1.12;Reactome: R-HSA-947581;MetaCyc: PWY-7887 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation" XP_030021435.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030024312.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037297376.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_030020108.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030030214.1 52 Reactome: R-HSA-167162;Reactome: R-HSA-72163;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-5250924;Reactome: R-HSA-9018519;Reactome: R-HSA-167243;Reactome: R-HSA-76061;Reactome: R-HSA-73772;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-72203;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-5601884;Reactome: R-HSA-73863;Reactome: R-HSA-112382;Reactome: R-HSA-6781827;Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-6796648;Reactome: R-HSA-6803529;Reactome: R-HSA-5617472;Reactome: R-HSA-75955;Reactome: R-HSA-168325;Reactome: R-HSA-167152;Reactome: R-HSA-1834949;Reactome: R-HSA-72086;Reactome: R-HSA-203927;Reactome: R-HSA-167238;Reactome: R-HSA-76071;Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-167287;Reactome: R-HSA-75953;Reactome: R-HSA-72165;Reactome: R-HSA-76066;Reactome: R-HSA-167161;Reactome: R-HSA-749476;Reactome: R-HSA-113418;Reactome: R-HSA-73780;Reactome: R-HSA-674695;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-167242;Reactome: R-HSA-73762;Reactome: R-HSA-6782135;Reactome: R-HSA-73980 "RNA Polymerase II HIV Promoter Escape";"mRNA Splicing - Major Pathway";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"B-WICH complex positively regulates rRNA expression";"Estrogen-dependent gene expression";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase I Transcription Termination";"Formation of RNA Pol II elongation complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"TP53 Regulates Transcription of DNA Repair Genes";"FGFR2 alternative splicing";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Transcription Elongation";"Viral Messenger RNA Synthesis";"Formation of HIV elongation complex in the absence of HIV Tat";"Cytosolic sensors of pathogen-associated DNA";"mRNA Capping";"MicroRNA (miRNA) biogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"HIV Transcription Initiation";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of the Early Elongation Complex";"RNA Polymerase III Chain Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase I Transcription Initiation";"Dual incision in TC-NER";"RNA Polymerase III Transcription Termination" XP_030040810.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_030028368.1 4 MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism" XP_030026925.2 8 KEGG: 00010+1.1.1.27;KEGG: 00270+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00620+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00640+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-8086 "Glycolysis / Gluconeogenesis";"Cysteine and methionine metabolism";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Pyruvate metabolism";"Propanoate metabolism";"Superpathway of glucose and xylose degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen" XP_037295885.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037296828.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_030021616.1 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" XP_037299792.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_037294081.1 8 Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083629;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921 "O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)" XP_030032689.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_030020020.1 5 Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5693554 "HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_030035344.1 6 Reactome: R-HSA-111367;Reactome: R-HSA-191859;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77588 "SLBP independent Processing of Histone Pre-mRNAs";"snRNP Assembly";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" XP_030026744.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_030032538.1 7 MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897;KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500 "Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis";"TP53 Regulates Metabolic Genes";"D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle" XP_030029627.2 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6785470 "tRNA processing in the nucleus";"tRNA processing in the mitochondrion" XP_037294970.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030029326.1 2 Reactome: R-HSA-70263;Reactome: R-HSA-70171 "Gluconeogenesis";"Glycolysis" XP_030028469.2 7 KEGG: 00630+2.3.3.9;MetaCyc: PWY-7295;MetaCyc: PWY-7118;MetaCyc: PWY-6969;MetaCyc: PWY-7294;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7854 "Glyoxylate and dicarboxylate metabolism";"L-arabinose degradation IV";"Chitin degradation to ethanol";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"D-xylose degradation IV";"Pyruvate metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)" XP_030032166.1 7 MetaCyc: PWY-7586;MetaCyc: PWY-5659;KEGG: 00051+5.4.2.8;MetaCyc: PWY-7456;KEGG: 00520+5.4.2.8;MetaCyc: PWY-882;Reactome: R-HSA-446205 "Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"GDP-mannose biosynthesis";"Fructose and mannose metabolism";"Beta-(1,4)-mannan degradation";"Amino sugar and nucleotide sugar metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Synthesis of GDP-mannose" XP_037298037.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037298225.1 14 Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-69273;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-450520;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-168333;Reactome: R-HSA-3769402;Reactome: R-HSA-2173788;Reactome: R-HSA-5687128;Reactome: R-HSA-9634638;Reactome: R-HSA-165054 "Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Cyclin A/B1/B2 associated events during G2/M transition";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HuR (ELAVL1) binds and stabilizes mRNA";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery";"Deactivation of the beta-catenin transactivating complex";"Downregulation of TGF-beta receptor signaling";"MAPK6/MAPK4 signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Rev-mediated nuclear export of HIV RNA" XP_030024950.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_030031790.2 17 KEGG: 05235+3.1.3.16;Reactome: R-HSA-113418;Reactome: R-HSA-167290;KEGG: 04658+3.1.3.16;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-167246;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167238 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Th1 and Th2 cell differentiation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"T cell receptor signaling pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation" XP_037297954.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340 "PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_030036324.1 10 Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-3214847;Reactome: R-HSA-73776 "HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"HATs acetylate histones";"RNA Polymerase II Promoter Escape" XP_030037035.1 4 Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport" XP_037293733.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_030040945.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_030032117.1 4 Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037301361.1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_030022962.1 56 Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091 "ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells" XP_030023496.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_030020595.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_030034819.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_030019713.1 10 MetaCyc: PWY-7559;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-7112;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842 "Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Glutathione-mediated detoxification II" XP_030035975.1 1 MetaCyc: PWY-6938 "NADH repair" XP_037295129.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-9033500 "Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins" XP_037295691.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030027629.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_030032332.2 1 Reactome: R-HSA-72731 "Recycling of eIF2:GDP" XP_030028874.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037300565.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" XP_030021488.2 7 Reactome: R-HSA-68827;Reactome: R-HSA-69205;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176187 "CDT1 association with the CDC6:ORC:origin complex";"G1/S-Specific Transcription";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress" XP_030025985.2 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_030033775.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_030027469.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_030040867.1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_037302278.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_037302556.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_037297195.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270 "Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes" XP_030031372.2 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_037298987.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_030031321.1 12 Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-3371497 "EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"HCMV Early Events";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_037300357.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037295824.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_030032399.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037295839.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037296748.1 3 Reactome: R-HSA-6807505;Reactome: R-HSA-749476;Reactome: R-HSA-76071 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_037294078.1 6 MetaCyc: PWY-5097;MetaCyc: PWY-8088;KEGG: 00261+4.3.3.7;KEGG: 00300+4.3.3.7;MetaCyc: PWY-2941;MetaCyc: PWY-2942 "L-lysine biosynthesis VI";"Dipicolinate biosynthesis";"Monobactam biosynthesis";"Lysine biosynthesis";"L-lysine biosynthesis II";"L-lysine biosynthesis III" XP_037292265.1 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_037299299.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037292937.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_030035967.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_030023569.2 2 KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_037298509.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_030033092.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_037303047.1 6 MetaCyc: PWY-7920;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426 "Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)" XP_030032647.2 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_030040031.2 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_037302759.1 42 Reactome: R-HSA-427359;Reactome: R-HSA-5625886;Reactome: R-HSA-8939236;Reactome: R-HSA-5250924;Reactome: R-HSA-9018519;Reactome: R-HSA-912446;Reactome: R-HSA-3214858;Reactome: R-HSA-8936459;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-9610379;Reactome: R-HSA-5334118;Reactome: R-HSA-2559582;Reactome: R-HSA-5693571;Reactome: R-HSA-1912408;Reactome: R-HSA-427389;Reactome: R-HSA-9609690;Reactome: R-HSA-73772;Reactome: R-HSA-606279;Reactome: R-HSA-69473;Reactome: R-HSA-171306;Reactome: R-HSA-110328;Reactome: R-HSA-110330;Reactome: R-HSA-4551638;Reactome: R-HSA-3214847;Reactome: R-HSA-3214815;Reactome: R-HSA-1221632;Reactome: R-HSA-3214841;Reactome: R-HSA-2559580;Reactome: R-HSA-977225;Reactome: R-HSA-5617472;Reactome: R-HSA-3214842;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-9616222;Reactome: R-HSA-212300;Reactome: R-HSA-5693565;Reactome: R-HSA-73728;Reactome: R-HSA-2299718;Reactome: R-HSA-110331;Reactome: R-HSA-110329 "SIRT1 negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"B-WICH complex positively regulates rRNA expression";"Estrogen-dependent gene expression";"Meiotic recombination";"RMTs methylate histone arginines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"HCMV Late Events";"DNA methylation";"Senescence-Associated Secretory Phenotype (SASP)";"Nonhomologous End-Joining (NHEJ)";"Pre-NOTCH Transcription and Translation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HCMV Early Events";"RNA Polymerase I Promoter Escape";"Deposition of new CENPA-containing nucleosomes at the centromere";"G2/M DNA damage checkpoint";"Packaging Of Telomere Ends";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"SUMOylation of chromatin organization proteins";"HATs acetylate histones";"HDACs deacetylate histones";"Meiotic synapsis";"PKMTs methylate histone lysines";"Oxidative Stress Induced Senescence";"Amyloid fiber formation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HDMs demethylate histones";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"Transcriptional regulation of granulopoiesis";"PRC2 methylates histones and DNA";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RNA Polymerase I Promoter Opening";"Condensation of Prophase Chromosomes";"Cleavage of the damaged purine";"Cleavage of the damaged pyrimidine" XP_037292236.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037300787.1 7 Reactome: R-HSA-6798695;Reactome: R-HSA-373753;Reactome: R-HSA-264870;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-375165 "Neutrophil degranulation";"Nephrin family interactions";"Caspase-mediated cleavage of cytoskeletal proteins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth" XP_030028428.1 25 Reactome: R-HSA-8939256;Reactome: R-HSA-9616222;Reactome: R-HSA-8951936;Reactome: R-HSA-8939242;Reactome: R-HSA-8935964;Reactome: R-HSA-8941333;Reactome: R-HSA-8941284;Reactome: R-HSA-8941326;Reactome: R-HSA-8877330;Reactome: R-HSA-8931987;Reactome: R-HSA-8939247;Reactome: R-HSA-8936459;Reactome: R-HSA-8940973;Reactome: R-HSA-8939245;Reactome: R-HSA-8941858;Reactome: R-HSA-8934593;Reactome: R-HSA-8939243;Reactome: R-HSA-8951911;Reactome: R-HSA-8949275;Reactome: R-HSA-8939902;Reactome: R-HSA-8878166;Reactome: R-HSA-8939246;Reactome: R-HSA-9018519;Reactome: R-HSA-8941332;Reactome: R-HSA-8939236 "RUNX1 regulates transcription of genes involved in WNT signaling";"Transcriptional regulation of granulopoiesis";"RUNX3 regulates p14-ARF";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX1 regulates expression of components of tight junctions";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX2 regulates chondrocyte maturation";"RUNX2 regulates bone development";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in BCR signaling";"Regulation of RUNX3 expression and activity";"Regulation of RUNX1 Expression and Activity";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX3 regulates RUNX1-mediated transcription";"RUNX3 Regulates Immune Response and Cell Migration";"Regulation of RUNX2 expression and activity";"Transcriptional regulation by RUNX2";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"Estrogen-dependent gene expression";"RUNX2 regulates genes involved in cell migration";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_030037911.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037302893.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-3371497 "COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"HCMV Early Events";"RHO GTPases Activate Formins";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_037300663.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_030020100.2 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_030024704.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037302598.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_030037706.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling" XP_030036572.2 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_037296738.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_030020499.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030021556.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_030027450.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_030028374.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037300164.1 10 Reactome: R-HSA-6798695;Reactome: R-HSA-2514853;Reactome: R-HSA-1483191;Reactome: R-HSA-201688;Reactome: R-HSA-8934903;Reactome: R-HSA-8948751;Reactome: R-HSA-6814122;Reactome: R-HSA-6804756;Reactome: R-HSA-8939243;Reactome: R-HSA-445144 "Neutrophil degranulation";"Condensation of Prometaphase Chromosomes";"Synthesis of PC";"WNT mediated activation of DVL";"Receptor Mediated Mitophagy";"Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of TP53 Activity through Phosphorylation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Signal transduction by L1" XP_030033052.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_030039850.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037298254.1 12 Reactome: R-HSA-451308;Reactome: R-HSA-399719;MetaCyc: PWY-7221;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-447038;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736 "Activation of Ca-permeable Kainate Receptor";"Trafficking of AMPA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"NrCAM interactions";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors" XP_030032271.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_030032434.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_030034281.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_037297787.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_030032923.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_037298343.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037297390.1 4 Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-400511 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)" XP_030024279.2 5 MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822 "Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)" XP_037295337.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_030032904.1 42 Reactome: R-HSA-171306;Reactome: R-HSA-110330;Reactome: R-HSA-4551638;Reactome: R-HSA-3214847;Reactome: R-HSA-110328;Reactome: R-HSA-3214841;Reactome: R-HSA-3214815;Reactome: R-HSA-1221632;Reactome: R-HSA-5617472;Reactome: R-HSA-977225;Reactome: R-HSA-2559580;Reactome: R-HSA-3214842;Reactome: R-HSA-2559586;Reactome: R-HSA-201722;Reactome: R-HSA-5693607;Reactome: R-HSA-73728;Reactome: R-HSA-2299718;Reactome: R-HSA-9616222;Reactome: R-HSA-212300;Reactome: R-HSA-5693565;Reactome: R-HSA-110331;Reactome: R-HSA-110329;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-9018519;Reactome: R-HSA-5250924;Reactome: R-HSA-8939236;Reactome: R-HSA-3214858;Reactome: R-HSA-912446;Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-8936459;Reactome: R-HSA-2559582;Reactome: R-HSA-9610379;Reactome: R-HSA-5334118;Reactome: R-HSA-5693571;Reactome: R-HSA-606279;Reactome: R-HSA-69473;Reactome: R-HSA-73772;Reactome: R-HSA-9609690;Reactome: R-HSA-1912408;Reactome: R-HSA-427389 "Packaging Of Telomere Ends";"Recognition and association of DNA glycosylase with site containing an affected purine";"SUMOylation of chromatin organization proteins";"HATs acetylate histones";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"PKMTs methylate histone lysines";"HDACs deacetylate histones";"Meiotic synapsis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Amyloid fiber formation";"Oxidative Stress Induced Senescence";"HDMs demethylate histones";"DNA Damage/Telomere Stress Induced Senescence";"Formation of the beta-catenin:TCF transactivating complex";"Processing of DNA double-strand break ends";"RNA Polymerase I Promoter Opening";"Condensation of Prophase Chromosomes";"Transcriptional regulation of granulopoiesis";"PRC2 methylates histones and DNA";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cleavage of the damaged purine";"Cleavage of the damaged pyrimidine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"Estrogen-dependent gene expression";"B-WICH complex positively regulates rRNA expression";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RMTs methylate histone arginines";"Meiotic recombination";"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Senescence-Associated Secretory Phenotype (SASP)";"HCMV Late Events";"DNA methylation";"Nonhomologous End-Joining (NHEJ)";"Deposition of new CENPA-containing nucleosomes at the centromere";"G2/M DNA damage checkpoint";"RNA Polymerase I Promoter Escape";"HCMV Early Events";"Pre-NOTCH Transcription and Translation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_030027980.1 5 MetaCyc: PWY-7177;MetaCyc: PWY-7185;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7176;Reactome: R-HSA-499943 "UTP and CTP dephosphorylation II";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates" XP_037301230.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037295343.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_030020301.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_030035840.2 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_037301004.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_030021617.1 26 Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-9648025;Reactome: R-HSA-983189;Reactome: R-HSA-389960;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-389977;Reactome: R-HSA-9646399;Reactome: R-HSA-380320;Reactome: R-HSA-8852276 "COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Cilium Assembly";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"HCMV Early Events";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"EML4 and NUDC in mitotic spindle formation";"Kinesins";"Formation of tubulin folding intermediates by CCT/TriC";"Mitotic Prometaphase";"Recycling pathway of L1";"Post-chaperonin tubulin folding pathway";"Aggrephagy";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint" XP_030040475.1 14 KEGG: 00190+1.3.5.1;MetaCyc: PWY-7279;MetaCyc: PWY-7254;MetaCyc: PWY-6969;MetaCyc: PWY-4302;MetaCyc: PWY-5690;MetaCyc: PWY-561;KEGG: 00720+1.3.5.1;Reactome: R-HSA-611105;KEGG: 00650+1.3.5.1;MetaCyc: PWY-6728;MetaCyc: PWY-3781;KEGG: 00020+1.3.5.1;Reactome: R-HSA-71403 "Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle VII (acetate-producers)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Respiratory electron transport";"Butanoate metabolism";"Methylaspartate cycle";"Aerobic respiration I (cytochrome c)";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)" XP_037303002.1 5 Reactome: R-HSA-3656237;MetaCyc: PWY-6558;Reactome: R-HSA-2022928;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656253 "Defective EXT2 causes exostoses 2";"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS" XP_030027568.2 19 MetaCyc: PWY-7224;MetaCyc: PWY-7197;MetaCyc: PWY-7210;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7222;Reactome: R-HSA-380320;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7187;MetaCyc: PWY-7227;Reactome: R-HSA-380270;MetaCyc: PWY-7198;MetaCyc: PWY-7221;MetaCyc: PWY-7220;MetaCyc: PWY-7184;MetaCyc: PWY-6545 "Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Pyrimidine metabolism";"CMP phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Recruitment of NuMA to mitotic centrosomes";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Recruitment of mitotic centrosome proteins and complexes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" XP_037299094.1 12 Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-381038;Reactome: R-HSA-8854518;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-3371497;Reactome: R-HSA-380284;Reactome: R-HSA-380320 "MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"XBP1(S) activates chaperone genes";"AURKA Activation by TPX2";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes" XP_030025760.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-112043 "G alpha (i) signalling events";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"PLC beta mediated events" XP_030036758.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_037297377.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_037293829.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_030024153.2 5 KEGG: 00620+4.1.1.32;Reactome: R-HSA-70263;MetaCyc: PWY-7383;KEGG: 00020+4.1.1.32;KEGG: 00010+4.1.1.32 "Pyruvate metabolism";"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis" XP_037293618.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_030036323.1 10 Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-3214847;Reactome: R-HSA-674695;Reactome: R-HSA-76042 "RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"HATs acetylate histones";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_030036719.2 5 Reactome: R-HSA-5579006;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403;KEGG: 00270+6.3.2.3 "Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Ophthalmate biosynthesis";"Glutathione metabolism";"Glutathione synthesis and recycling";"Cysteine and methionine metabolism" XP_037296124.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_037303177.1 2 KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_030035428.1 24 KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-202424;Reactome: R-HSA-392451;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-114604;Reactome: R-HSA-6804757;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-5218921;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2730905;Reactome: R-HSA-5218920;Reactome: R-HSA-9634635;Reactome: R-HSA-165158;Reactome: R-HSA-5607764;Reactome: R-HSA-389357;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2871837;Reactome: R-HSA-1257604;Reactome: R-HSA-444257;KEGG: 04150+2.7.11.1 "Human cytomegalovirus infection";"Thermogenesis";"Integrin signaling";"Downstream TCR signaling";"G beta:gamma signalling through PI3Kgamma";"Human immunodeficiency virus 1 infection";"Constitutive Signaling by AKT1 E17K in Cancer";"GPVI-mediated activation cascade";"Regulation of TP53 Degradation";"PI3K-Akt signaling pathway";"RHO GTPases activate PKNs";"VEGFR2 mediated cell proliferation";"Relaxin signaling pathway";"Role of LAT2/NTAL/LAB on calcium mobilization";"VEGFR2 mediated vascular permeability";"Estrogen-stimulated signaling through PRKCZ";"Activation of AKT2";"CLEC7A (Dectin-1) signaling";"CD28 dependent PI3K/Akt signaling";"Human papillomavirus infection";"FCERI mediated NF-kB activation";"PIP3 activates AKT signaling";"RSK activation";"mTOR signaling pathway" XP_037301701.1 2 Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13 "Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system" XP_030033781.1 6 Reactome: R-HSA-2029485;Reactome: R-HSA-1489509;Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13;Reactome: R-HSA-1250196;Reactome: R-HSA-418597 "Role of phospholipids in phagocytosis";"DAG and IP3 signaling";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"SHC1 events in ERBB2 signaling";"G alpha (z) signalling events" XP_037297498.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_030024483.2 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_030025256.2 2 Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_030030178.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030029172.1 13 MetaCyc: PWY-7222;Reactome: R-HSA-499943;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;MetaCyc: PWY-6545;MetaCyc: PWY-7184;MetaCyc: PWY-7220;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7226;KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7210 "Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" XP_030041027.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_030032007.1 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" XP_037301527.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030021652.1 26 Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-389977;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-389960;Reactome: R-HSA-983189;Reactome: R-HSA-9648025 "Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"HCMV Early Events";"Cilium Assembly";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"Aggrephagy";"Post-chaperonin tubulin folding pathway";"Recycling pathway of L1";"Mitotic Prometaphase";"Formation of tubulin folding intermediates by CCT/TriC";"Kinesins";"EML4 and NUDC in mitotic spindle formation" XP_030030730.2 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037293885.1 33 Reactome: R-HSA-4615885;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-3232142;Reactome: R-HSA-2467813;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-168325;Reactome: R-HSA-9648025;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-4551638;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-141444;Reactome: R-HSA-180746;Reactome: R-HSA-159231;Reactome: R-HSA-68877;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-6784531 "SUMOylation of DNA replication proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of ubiquitinylation proteins";"Separation of Sister Chromatids";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Viral Messenger RNA Synthesis";"EML4 and NUDC in mitotic spindle formation";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"SUMOylation of chromatin organization proteins";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Nuclear import of Rev protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Mitotic Prometaphase";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus" XP_030035957.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_030029053.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037295686.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_030021212.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_030028503.1 4 Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437 "UCH proteinases";"HATs acetylate histones";"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation" XP_037295364.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_030030007.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_037294416.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_030024124.2 11 MetaCyc: PWY-381;MetaCyc: PWY-5675;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6963;KEGG: 00910+6.3.1.2;KEGG: 00220+6.3.1.2;Reactome: R-HSA-210455;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6549;MetaCyc: PWY-6964;Reactome: R-HSA-8964539 "Nitrate reduction II (assimilatory)";"Nitrate reduction V (assimilatory)";"Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle I";"Nitrogen metabolism";"Arginine biosynthesis";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Alanine, aspartate and glutamate metabolism";"L-glutamine biosynthesis III";"Ammonia assimilation cycle II";"Glutamate and glutamine metabolism" XP_037297924.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_030021066.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030040735.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_030021957.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_037299052.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_037293628.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_030040073.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030024201.2 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037297169.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_030024698.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_030038460.1 6 Reactome: R-HSA-5654693;Reactome: R-HSA-5654712;Reactome: R-HSA-5654706;Reactome: R-HSA-5654700;Reactome: R-HSA-5673001;Reactome: R-HSA-9028731 "FRS-mediated FGFR1 signaling";"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR2 signaling";"RAF/MAP kinase cascade";"Activated NTRK2 signals through FRS2 and FRS3" XP_037293158.1 5 Reactome: R-HSA-983231;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295 "Factors involved in megakaryocyte development and platelet production";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation" XP_030032384.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037292662.1 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" XP_030023620.2 4 MetaCyc: PWY-7849;MetaCyc: PWY-5691;MetaCyc: PWY-7394;KEGG: 00230+4.1.1.97 "Urate conversion to allantoin III";"Urate conversion to allantoin I";"Urate conversion to allantoin II";"Purine metabolism" XP_030027628.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_037298985.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_037301231.1 2 KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019 "Pyrimidine metabolism";"Pseudouridine degradation" XP_030022682.1 2 Reactome: R-HSA-68962;Reactome: R-HSA-176187 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress" XP_037297864.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_030021554.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_030040679.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_030029907.1 29 KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2559586;Reactome: R-HSA-69541;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804760;Reactome: R-HSA-349425;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-3371453;Reactome: R-HSA-6804756;Reactome: R-HSA-6803207;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-5693554;Reactome: R-HSA-6796648;Reactome: R-HSA-5693548;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5685942;KEGG: 05165+2.7.11.1;Reactome: R-HSA-912446;Reactome: R-HSA-6803204 "Human immunodeficiency virus 1 infection";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Thermogenesis";"Human cytomegalovirus infection";"DNA Damage/Telomere Stress Induced Senescence";"Stabilization of p53";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Relaxin signaling pathway";"Regulation of TP53 Activity through Methylation";"Autodegradation of the E3 ubiquitin ligase COP1";"PI3K-Akt signaling pathway";"Regulation of TP53 Degradation";"Regulation of HSF1-mediated heat shock response";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"TP53 Regulates Transcription of DNA Repair Genes";"Sensing of DNA Double Strand Breaks";"mTOR signaling pathway";"HDR through Homologous Recombination (HRR)";"Human papillomavirus infection";"Meiotic recombination";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_030033758.2 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_030032755.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_030032370.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037296829.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_030024537.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156902 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Peptide chain elongation" XP_030019714.1 10 MetaCyc: PWY-7112;MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-7559;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-5826 "4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis" XP_030030223.1 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" XP_037296471.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_030020151.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_030024393.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030037335.2 11 Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-5689880;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-3214847;Reactome: R-HSA-674695;Reactome: R-HSA-76042 "RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"Ub-specific processing proteases";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"HATs acetylate histones";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_037302347.1 29 Reactome: R-HSA-5696400;Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-167160;Reactome: R-HSA-75955;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-5696395;Reactome: R-HSA-73863;Reactome: R-HSA-113418;Reactome: R-HSA-6782135;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-73772;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-77075 "Dual Incision in GG-NER";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Termination";"Formation of the Early Elongation Complex";"Dual incision in TC-NER";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE" XP_037296337.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_030032536.1 7 KEGG: 00471+3.5.1.2;Reactome: R-HSA-210500;KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-5628897 "D-Glutamine and D-glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes" XP_030031175.2 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_037295797.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_037297725.1 4 Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_037292967.1 42 KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;KEGG: 00410+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;KEGG: 00640+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;MetaCyc: PWY-1361;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00623+1.1.1.35;KEGG: 00627+4.2.1.17;MetaCyc: PWY-5109;KEGG: 00360+4.2.1.17;MetaCyc: PWY-6944;MetaCyc: PWY-7654;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;MetaCyc: PWY-5138;MetaCyc: PWY-7094;MetaCyc: PWY-7656;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;MetaCyc: PWY-6863;MetaCyc: PWY-6946;KEGG: 00903+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;MetaCyc: PWY-7007;MetaCyc: PWY-6883;MetaCyc: PWY-6583;MetaCyc: PWY-5177;MetaCyc: PWY-7401 "Carbon fixation pathways in prokaryotes";"alpha-Linolenic acid metabolism";"Lysine degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism";"Tryptophan metabolism";"2-methylpropene degradation";"Fatty acid degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Propanoate metabolism";"Valine, leucine and isoleucine degradation";"Methyl tert-butyl ether degradation";"Fatty acid degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Benzoyl-coa degradation I (aerobic)";"Fatty acid elongation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Toluene degradation";"Aminobenzoate degradation";"Fermentation to 2-methylbutanoate";"Phenylalanine metabolism";"Androstenedione degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Benzoate degradation";"Butanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Fatty acid salvage";"Spodoptera littoralis pheromone biosynthesis";"Butanoate metabolism";"Geraniol degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Pyruvate fermentation to hexanol (engineered)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Limonene and pinene degradation";"Caprolactam degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Methyl ketone biosynthesis (engineered)";"Pyruvate fermentation to butanol II (engineered)";"Pyruvate fermentation to butanol I";"Glutaryl-coa degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)" XP_030038346.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037302858.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037303287.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037303382.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6798695 "Protein ubiquitination";"Neutrophil degranulation" XP_037300019.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_030020582.1 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_030021104.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_030032006.1 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" XP_030026600.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_037295452.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_030030201.2 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_030034205.2 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037300918.1 6 MetaCyc: PWY-7791;MetaCyc: PWY-7790;KEGG: 00983+2.4.2.10;KEGG: 00240+2.4.2.10;MetaCyc: PWY-5686;Reactome: R-HSA-500753 "UMP biosynthesis III";"UMP biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"UMP biosynthesis I";"Pyrimidine biosynthesis" XP_030035929.2 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_037295499.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_030023156.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037293842.1 2 KEGG: 00500+3.2.1.26;KEGG: 00052+3.2.1.26 "Starch and sucrose metabolism";"Galactose metabolism" XP_037293371.1 4 Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport" XP_037302083.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030039000.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_030019685.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037297630.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037303269.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_030022683.1 6 Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;Reactome: R-HSA-8950505;Reactome: R-HSA-2151201;Reactome: R-HSA-8862803;MetaCyc: PWY-6854 "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Transcriptional activation of mitochondrial biogenesis";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Ethylene biosynthesis III (microbes)" XP_030032601.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_037297145.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_030031476.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_030024292.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_030024424.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030023796.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72706 "Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_030028820.2 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037301009.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_037301540.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-429958 "Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease" XP_037299030.1 2 Reactome: R-HSA-5601884;Reactome: R-HSA-1221632 "PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis" XP_030028182.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037295381.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030020253.2 5 Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2 "Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism" XP_037299353.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_030028840.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_030040335.1 14 Reactome: R-HSA-611105;KEGG: 00720+1.3.5.1;MetaCyc: PWY-561;MetaCyc: PWY-5690;MetaCyc: PWY-4302;MetaCyc: PWY-6969;MetaCyc: PWY-7254;KEGG: 00190+1.3.5.1;MetaCyc: PWY-7279;Reactome: R-HSA-71403;MetaCyc: PWY-3781;MetaCyc: PWY-6728;KEGG: 00020+1.3.5.1;KEGG: 00650+1.3.5.1 "Respiratory electron transport";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle VII (acetate-producers)";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Citric acid cycle (TCA cycle)";"Aerobic respiration I (cytochrome c)";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Butanoate metabolism" XP_037296306.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037298320.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_030033413.2 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_037292724.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_030024725.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_030031190.2 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_030041186.1 11 Reactome: R-HSA-400206;Reactome: R-HSA-1989781;Reactome: R-HSA-383280;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-400253;Reactome: R-HSA-2151201;Reactome: R-HSA-212436;Reactome: R-HSA-1368108;Reactome: R-HSA-9018519;Reactome: R-HSA-2426168 "Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression";"Nuclear Receptor transcription pathway";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis";"Generic Transcription Pathway";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Estrogen-dependent gene expression";"Activation of gene expression by SREBF (SREBP)" XP_037302226.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_030027036.2 4 KEGG: 00513+2.4.1.258;KEGG: 00510+2.4.1.258;Reactome: R-HSA-4720475;Reactome: R-HSA-446193 "Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Defective ALG3 causes ALG3-CDG (CDG-1d)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_030027863.2 1 Reactome: R-HSA-379716 "Cytosolic tRNA aminoacylation" XP_037301297.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_037295414.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_037298263.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037295300.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_030034269.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037294953.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_030031553.2 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_037294739.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037296473.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_037298820.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_030028757.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_037301928.1 7 Reactome: R-HSA-1483226;MetaCyc: PWY-7625;KEGG: 00564+2.7.8.11;KEGG: 04070+2.7.8.11;MetaCyc: PWY-6352;MetaCyc: PWY-6351;KEGG: 00562+2.7.8.11 "Synthesis of PI";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"3-phosphoinositide biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism" XP_030036561.1 5 Reactome: R-HSA-9633012;Reactome: R-HSA-380994;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895;Reactome: R-HSA-8963693 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"Aspartate and asparagine metabolism" XP_030040860.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_030027969.1 5 Reactome: R-HSA-5617472;Reactome: R-HSA-3769402;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-201722 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex" XP_030030000.1 11 KEGG: 04926+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05165+2.7.11.1;Reactome: R-HSA-171007;Reactome: R-HSA-450302;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"VEGFA-VEGFR2 Pathway";"Human papillomavirus infection";"p38MAPK events";"activated TAK1 mediates p38 MAPK activation";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis" XP_030029394.1 4 MetaCyc: PWY-7221;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541 "Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Abacavir metabolism" XP_030023964.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_030037701.1 3 KEGG: 00860+1.3.3.4;Reactome: R-HSA-189451;MetaCyc: PWY-7159 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)" XP_030025702.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73776 "Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape" XP_037297494.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037302538.1 2 Reactome: R-HSA-8953750;Reactome: R-HSA-8939243 "Transcriptional Regulation by E2F6";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_030031612.2 37 Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-159230;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-141444;Reactome: R-HSA-204005;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-983170;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-2132295;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-9639288;Reactome: R-HSA-191859 "HCMV Early Events";"RHO GTPases Activate Formins";"Transport of the SLBP Dependant Mature mRNA";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPII-mediated vesicle transport";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Mitotic Prometaphase";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"MHC class II antigen presentation";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Amino acids regulate mTORC1";"snRNP Assembly" XP_037296031.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_030029956.2 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_030025808.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037296155.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030029895.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030021037.1 8 Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-8948747;Reactome: R-HSA-6782135;Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-6782210;Reactome: R-HSA-8866652 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Regulation of PTEN localization";"Dual incision in TC-NER";"Ub-specific processing proteases";"Regulation of TP53 Degradation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes" XP_037295513.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_037298733.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_030033651.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_030026012.2 17 MetaCyc: PWY-7115;KEGG: 00680+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-5913;MetaCyc: PWY-5690;KEGG: 00620+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00710+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-561;KEGG: 00630+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5392;KEGG: 00020+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-6969 "C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Methane metabolism";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Pyruvate metabolism";"Cysteine and methionine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation in photosynthetic organisms";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glyoxylate cycle and fatty acid degradation";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Formaldehyde assimilation I (serine pathway)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" XP_030023669.1 8 KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1 "Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Fructose and mannose metabolism" XP_030030892.2 2 KEGG: 00513+2.4.1.142;KEGG: 00510+2.4.1.142 "Various types of N-glycan biosynthesis";"N-Glycan biosynthesis" XP_030030662.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_030033462.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436 "MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic" XP_030040496.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030022038.2 14 KEGG: 00650+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-6728;MetaCyc: PWY-3781;Reactome: R-HSA-71403;KEGG: 00190+1.3.5.1;MetaCyc: PWY-7254;MetaCyc: PWY-7279;MetaCyc: PWY-5690;MetaCyc: PWY-4302;MetaCyc: PWY-6969;MetaCyc: PWY-561;KEGG: 00720+1.3.5.1;Reactome: R-HSA-611105 "Butanoate metabolism";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Aerobic respiration I (cytochrome c)";"Citric acid cycle (TCA cycle)";"Oxidative phosphorylation";"TCA cycle VII (acetate-producers)";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle II (plants and fungi)";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Respiratory electron transport" XP_030036009.1 1 Reactome: R-HSA-8849175 "Threonine catabolism" XP_030032929.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-6791226 "Association of TriC/CCT with target proteins during biosynthesis";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_030026602.2 2 Reactome: R-HSA-2022377;Reactome: R-HSA-6798695 "Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation" XP_030027264.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_037295451.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_030027967.1 5 Reactome: R-HSA-3214841;Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-5617472;Reactome: R-HSA-3769402 "PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex" XP_030028193.2 6 Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_030034931.2 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_030031464.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_030022820.2 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037292675.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037295486.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_030025184.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_030030475.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-1358803;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination" XP_030034757.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037297646.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825 "Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis" XP_030024683.2 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_037293222.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030033783.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037295065.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_037295187.1 4 MetaCyc: PWY-8026;KEGG: 00100+1.3.1.72;Reactome: R-HSA-6807047;Reactome: R-HSA-6807062 "Sterol biosynthesis (methylotrophs)";"Steroid biosynthesis";"Cholesterol biosynthesis via desmosterol";"Cholesterol biosynthesis via lathosterol" XP_037296869.1 4 Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_037296262.1 5 KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;MetaCyc: PWY-6558;Reactome: R-HSA-2022928 "Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis" XP_030024748.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_030026274.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030033411.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription" XP_030040697.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030027309.1 11 Reactome: R-HSA-5620912;Reactome: R-HSA-2132295;Reactome: R-HSA-8854518;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-3371497;Reactome: R-HSA-380284;Reactome: R-HSA-380320 "Anchoring of the basal body to the plasma membrane";"MHC class II antigen presentation";"AURKA Activation by TPX2";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes" XP_037301936.1 6 Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-181429 "Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_030036867.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_037298984.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_030020234.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_030024751.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037299491.1 14 MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-5972 "Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)" XP_037301750.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_030032830.2 2 Reactome: R-HSA-111458;Reactome: R-HSA-9627069 "Formation of apoptosome";"Regulation of the apoptosome activity" XP_030030242.2 2 Reactome: R-HSA-156581;Reactome: R-HSA-72764 "Methylation";"Eukaryotic Translation Termination" XP_030020212.2 6 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes" XP_037298532.1 19 MetaCyc: PWY-7226;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7187;MetaCyc: PWY-7221;Reactome: R-HSA-380270;MetaCyc: PWY-7198;MetaCyc: PWY-6545;MetaCyc: PWY-7220;MetaCyc: PWY-7184;MetaCyc: PWY-7197;MetaCyc: PWY-7224;MetaCyc: PWY-7210;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7222;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7205;Reactome: R-HSA-380320 "Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Recruitment of mitotic centrosome proteins and complexes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"CMP phosphorylation";"Recruitment of NuMA to mitotic centrosomes" XP_037295478.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" XP_030032717.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_037292753.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_037302473.1 3 Reactome: R-HSA-5358565;Reactome: R-HSA-5632968;Reactome: R-HSA-5632928 "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2" XP_037299642.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_030027342.1 5 MetaCyc: PWY-6344;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981;Reactome: R-HSA-8964539 "L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism" XP_030033682.1 3 MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6 "Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism" XP_037301365.1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_030022164.2 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_037298815.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_030040675.2 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_030040848.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-975957 "mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_030020585.1 3 Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894 "Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation" XP_037303223.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_030033999.2 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_037293521.1 9 KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-112043;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;Reactome: R-HSA-416476;MetaCyc: PWY-6367 "Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism" XP_030026598.1 5 Reactome: R-HSA-9630221;Reactome: R-HSA-9630222;Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110357 "Defective NTHL1 substrate processing";"Defective NTHL1 substrate binding";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1" XP_030020327.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_030029671.1 13 MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902 "Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"CS/DS degradation";"Other glycan degradation";"Chitin degradation II (Vibrio)" XP_030037416.1 4 KEGG: 00270+4.1.1.50;MetaCyc: PWY-6834;Reactome: R-HSA-351202;KEGG: 00330+4.1.1.50 "Cysteine and methionine metabolism";"Spermidine biosynthesis III";"Metabolism of polyamines";"Arginine and proline metabolism" XP_037302521.1 2 Reactome: R-HSA-8853659;Reactome: R-HSA-5673001 "RET signaling";"RAF/MAP kinase cascade" XP_030040385.1 5 Reactome: R-HSA-5632684;Reactome: R-HSA-373080;Reactome: R-HSA-5610787;Reactome: R-HSA-5635838;Reactome: R-HSA-5620922 "Hedgehog 'on' state";"Class B/2 (Secretin family receptors)";"Hedgehog 'off' state";"Activation of SMO";"BBSome-mediated cargo-targeting to cilium" XP_030020395.2 6 Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556 "Neutrophil degranulation";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes" XP_037299121.1 5 Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-1655829 "Cargo concentration in the ER";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_037294566.1 2 Reactome: R-HSA-2142700;Reactome: R-HSA-2142691 "Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_037296997.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_037296462.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037296696.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_030021411.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_030021213.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037295753.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037297357.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_037292357.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_030032588.2 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_037301246.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035 "Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"(9Z)-tricosene biosynthesis" XP_030036721.2 5 Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;Reactome: R-HSA-174403;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3 "Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Glutathione metabolism" XP_037293485.1 9 Reactome: R-HSA-196780;KEGG: 00720+6.4.1.1;KEGG: 00620+6.4.1.1;MetaCyc: PWY-6146;MetaCyc: PWY-6142;MetaCyc: PWY-8086;KEGG: 00020+6.4.1.1;Reactome: R-HSA-3371599;Reactome: R-HSA-70263 "Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Defective HLCS causes multiple carboxylase deficiency";"Gluconeogenesis" XP_037292904.1 7 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_030036657.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037297492.1 2 Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_037297297.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_030039866.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_037293422.1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway" XP_030031778.1 7 KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-7214 "Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)" XP_037297434.1 3 Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2 "Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway" XP_037297431.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2 "VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway" XP_030030647.2 2 Reactome: R-HSA-432720;Reactome: R-HSA-432722 "Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis" XP_030029476.2 3 KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693 "Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism" XP_030022487.2 3 Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;Reactome: R-HSA-5696394 "UCH proteinases";"HATs acetylate histones";"DNA Damage Recognition in GG-NER" XP_030032535.1 7 Reactome: R-HSA-210500;KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00471+3.5.1.2;Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921 "Glutamate Neurotransmitter Release Cycle";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"D-Glutamine and D-glutamate metabolism";"TP53 Regulates Metabolic Genes";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation" XP_030035886.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_030032161.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_030030866.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030025215.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_030029217.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037301886.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450385 "ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" XP_030039815.2 42 Reactome: R-HSA-3214841;Reactome: R-HSA-3214815;Reactome: R-HSA-1221632;Reactome: R-HSA-5617472;Reactome: R-HSA-977225;Reactome: R-HSA-2559580;Reactome: R-HSA-171306;Reactome: R-HSA-3214847;Reactome: R-HSA-4551638;Reactome: R-HSA-110330;Reactome: R-HSA-110328;Reactome: R-HSA-73728;Reactome: R-HSA-2299718;Reactome: R-HSA-5693565;Reactome: R-HSA-9616222;Reactome: R-HSA-212300;Reactome: R-HSA-110329;Reactome: R-HSA-110331;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-3214842;Reactome: R-HSA-5693607;Reactome: R-HSA-3214858;Reactome: R-HSA-912446;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-5250924;Reactome: R-HSA-9018519;Reactome: R-HSA-8939236;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-606279;Reactome: R-HSA-73772;Reactome: R-HSA-427389;Reactome: R-HSA-1912408;Reactome: R-HSA-9609690;Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-8936459;Reactome: R-HSA-2559582;Reactome: R-HSA-9610379;Reactome: R-HSA-5334118 "PKMTs methylate histone lysines";"HDACs deacetylate histones";"Meiotic synapsis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Amyloid fiber formation";"Oxidative Stress Induced Senescence";"Packaging Of Telomere Ends";"HATs acetylate histones";"SUMOylation of chromatin organization proteins";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"RNA Polymerase I Promoter Opening";"Condensation of Prophase Chromosomes";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Transcriptional regulation of granulopoiesis";"PRC2 methylates histones and DNA";"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"HDMs demethylate histones";"Processing of DNA double-strand break ends";"RMTs methylate histone arginines";"Meiotic recombination";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"Estrogen-dependent gene expression";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Deposition of new CENPA-containing nucleosomes at the centromere";"RNA Polymerase I Promoter Escape";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Pre-NOTCH Transcription and Translation";"HCMV Early Events";"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Senescence-Associated Secretory Phenotype (SASP)";"HCMV Late Events";"DNA methylation" XP_037302302.1 10 Reactome: R-HSA-76042;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167172 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome" XP_030028940.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037296192.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_037301726.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_030029088.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037303371.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037292678.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030038417.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030040154.2 13 Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553 "Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs" XP_037294703.1 13 Reactome: R-HSA-112043;Reactome: R-HSA-2029485;Reactome: R-HSA-139853;Reactome: R-HSA-114508;Reactome: R-HSA-4086398;Reactome: R-HSA-381676;Reactome: R-HSA-5578775;Reactome: R-HSA-2871809;Reactome: R-HSA-5607763;Reactome: R-HSA-1489509;Reactome: R-HSA-5218921;Reactome: R-HSA-422356;Reactome: R-HSA-983695 "PLC beta mediated events";"Role of phospholipids in phagocytosis";"Elevation of cytosolic Ca2+ levels";"Effects of PIP2 hydrolysis";"Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ion homeostasis";"FCERI mediated Ca+2 mobilization";"CLEC7A (Dectin-1) induces NFAT activation";"DAG and IP3 signaling";"VEGFR2 mediated cell proliferation";"Regulation of insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers" XP_037295817.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_030035221.2 3 Reactome: R-HSA-2024096;Reactome: R-HSA-2024101;Reactome: R-HSA-2206296 "HS-GAG degradation";"CS/DS degradation";"MPS II - Hunter syndrome" XP_037293282.1 9 KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection" XP_037301421.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_030037704.1 1 Reactome: R-HSA-480985 "Synthesis of dolichyl-phosphate-glucose" XP_037297696.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_037300532.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_030041089.2 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_037297798.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_030029918.1 5 KEGG: 00561+2.3.1.20;Reactome: R-HSA-6798695;Reactome: R-HSA-1482883;Reactome: R-HSA-75109;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Neutrophil degranulation";"Acyl chain remodeling of DAG and TAG";"Triglyceride biosynthesis";"Cutin, suberine and wax biosynthesis" XP_030041004.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037294290.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_037299009.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_037292895.1 7 KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_030021508.1 19 Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-6802955;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-111932;Reactome: R-HSA-399719 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Long-term potentiation";"RAF/MAP kinase cascade";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"Ion transport by P-type ATPases";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"CaMK IV-mediated phosphorylation of CREB";"Trafficking of AMPA receptors" XP_030039361.2 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037300393.1 2 Reactome: R-HSA-196780;Reactome: R-HSA-3371599 "Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency" XP_030023682.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_030027284.1 1 MetaCyc: PWY-7379 "Mrna capping II" XP_030023512.1 3 Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-5685942 "Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)" XP_037298357.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_030021602.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226 "Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_030020692.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_037295775.1 6 Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-3769402 "Ca2+ pathway";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex" XP_030038253.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-8949215 "Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport" XP_037298801.1 11 Reactome: R-HSA-3560783;Reactome: R-HSA-4420332;Reactome: R-HSA-2022928;Reactome: R-HSA-3560801;Reactome: R-HSA-1971475;Reactome: R-HSA-3656253;Reactome: R-HSA-3000170;Reactome: R-HSA-2024096;Reactome: R-HSA-202733;Reactome: R-HSA-975634;Reactome: R-HSA-3656237 "Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG biosynthesis";"Defective B3GAT3 causes JDSSDHD";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Syndecan interactions";"HS-GAG degradation";"Cell surface interactions at the vascular wall";"Retinoid metabolism and transport";"Defective EXT2 causes exostoses 2" XP_037292220.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037302238.1 2 Reactome: R-HSA-195253;Reactome: R-HSA-5689896 "Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases" XP_030025973.2 1 Reactome: R-HSA-163125 "Post-translational modification: synthesis of GPI-anchored proteins" XP_030026475.2 52 Reactome: R-HSA-168325;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-5617472;Reactome: R-HSA-6803529;Reactome: R-HSA-203927;Reactome: R-HSA-167238;Reactome: R-HSA-72086;Reactome: R-HSA-1834949;Reactome: R-HSA-73776;Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-75953;Reactome: R-HSA-72165;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73780;Reactome: R-HSA-113418;Reactome: R-HSA-6782135;Reactome: R-HSA-73980;Reactome: R-HSA-76042;Reactome: R-HSA-6781823;Reactome: R-HSA-73762;Reactome: R-HSA-167242;Reactome: R-HSA-167162;Reactome: R-HSA-8851708;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-5250924;Reactome: R-HSA-9018519;Reactome: R-HSA-167243;Reactome: R-HSA-76061;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-73772;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-72203;Reactome: R-HSA-73863;Reactome: R-HSA-5601884;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-5578749;Reactome: R-HSA-6781827;Reactome: R-HSA-427413 "Viral Messenger RNA Synthesis";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"FGFR2 alternative splicing";"MicroRNA (miRNA) biogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Capping";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase III Chain Elongation";"Formation of the Early Elongation Complex";"Dual incision in TC-NER";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II HIV Promoter Escape";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"B-WICH complex positively regulates rRNA expression";"Estrogen-dependent gene expression";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase I Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase I Transcription Termination";"PIWI-interacting RNA (piRNA) biogenesis";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Transcriptional regulation by small RNAs";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NoRC negatively regulates rRNA expression" XP_030025759.1 4 Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-418594;Reactome: R-HSA-112043 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"G alpha (i) signalling events";"PLC beta mediated events" XP_037297378.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_030025007.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_030037907.1 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" XP_030023160.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030029017.1 3 Reactome: R-HSA-380994;Reactome: R-HSA-429947;Reactome: R-HSA-450604 "ATF4 activates genes in response to endoplasmic reticulum stress";"Deadenylation of mRNA";"KSRP (KHSRP) binds and destabilizes mRNA" XP_037299369.1 14 MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7601 "(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_030041151.1 4 KEGG: 00750+1.4.3.5;Reactome: R-HSA-964975;MetaCyc: PWY-7282;MetaCyc: PWY-7204 "Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)" XP_030034103.2 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_030034475.2 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_030020181.1 8 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Signaling by Hippo";"Human cytomegalovirus infection";"Thermogenesis" XP_030031560.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_030029136.1 4 Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-389661;Reactome: R-HSA-77289 "Complex I biogenesis";"Respiratory electron transport";"Glyoxylate metabolism and glycine degradation";"Mitochondrial Fatty Acid Beta-Oxidation" XP_030033046.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-156902 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation" XP_030027963.1 5 Reactome: R-HSA-5617472;Reactome: R-HSA-3769402;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-201722 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex" XP_030022295.1 6 KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039 "Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule" XP_037292691.1 6 Reactome: R-HSA-6803207;Reactome: R-HSA-6803204;Reactome: R-HSA-6803211;Reactome: R-HSA-6803205;Reactome: R-HSA-139915;Reactome: R-HSA-6804759 "TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria";"Regulation of TP53 Activity through Association with Co-factors" XP_030021523.2 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_037294559.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_030038864.1 18 KEGG: 00983+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7224;MetaCyc: PWY-7197;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7205;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7187;MetaCyc: PWY-7227;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7184;MetaCyc: PWY-7220;MetaCyc: PWY-6545;MetaCyc: PWY-7198;MetaCyc: PWY-7221 "Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotide phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine ribonucleotides de novo biosynthesis" XP_030030884.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_030032372.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030024816.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_030032232.1 11 Reactome: R-HSA-164378;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-170670 "PKA activation in glucagon signalling";"G alpha (i) signalling events";"Purine metabolism";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"Hedgehog 'off' state";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway" XP_037294188.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030020589.1 3 Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894 "Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation" XP_030038439.1 2 Reactome: R-HSA-2142691;Reactome: R-HSA-2142700 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)" XP_037302889.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_030025077.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_030027302.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_037295094.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_030041048.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_030034801.2 3 Reactome: R-HSA-5607761;Reactome: R-HSA-5621575;Reactome: R-HSA-5676590 "Dectin-1 mediated noncanonical NF-kB signaling";"CD209 (DC-SIGN) signaling";"NIK-->noncanonical NF-kB signaling" XP_037294523.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_037301178.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030025240.2 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_037292346.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037302753.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_030040938.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_037300836.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037298262.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_030032030.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_030037062.1 4 Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001 "Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade" XP_037299998.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_037295249.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_030020136.2 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037292491.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037294110.1 2 Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77 "Methionine salvage pathway";"Cysteine and methionine metabolism" XP_030041298.2 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway" XP_030034296.2 5 MetaCyc: PWY-7922;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis" XP_030028520.1 7 MetaCyc: PWY-6605;Reactome: R-HSA-74217;MetaCyc: PWY-7807;KEGG: 00230+2.4.2.7;MetaCyc: PWY-6610;Reactome: R-HSA-6798695;MetaCyc: PWY-7805 "Adenine and adenosine salvage II";"Purine salvage";"Glyphosate degradation III";"Purine metabolism";"Adenine salvage";"Neutrophil degranulation";"(aminomethyl)phosphonate degradation" XP_037292914.1 7 Reactome: R-HSA-70268;Reactome: R-HSA-5362517;KEGG: 00010+2.3.1.12;Reactome: R-HSA-389661;KEGG: 00020+2.3.1.12;KEGG: 00620+2.3.1.12;Reactome: R-HSA-204174 "Pyruvate metabolism";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_030023636.2 12 MetaCyc: PWY-5872;MetaCyc: PWY-5856;MetaCyc: PWY-6708;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5870;Reactome: R-HSA-2142789;MetaCyc: PWY-5855;MetaCyc: PWY-5857;MetaCyc: PWY-7230;MetaCyc: PWY-5873;MetaCyc: PWY-7233;MetaCyc: PWY-5871 "Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)" XP_037293728.1 8 Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852 "HSF1-dependent transactivation";"mTORC1-mediated signalling";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Macroautophagy" XP_037293005.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_037301465.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_030021448.1 3 Reactome: R-HSA-1799339;Reactome: R-HSA-1236974;Reactome: R-HSA-9609523 "SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_037292684.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_030019961.1 13 MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52 "Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series" XP_030020846.1 2 KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205 "Starch and sucrose metabolism";"Synthesis of GDP-mannose" XP_037301628.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_030028920.1 6 Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_030030330.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_030033740.1 3 KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508;Reactome: R-HSA-418597 "Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"G alpha (z) signalling events" XP_037292640.1 4 KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.6 "Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"Metabolism of folate and pterines";"One carbon pool by folate" XP_037302016.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_037301480.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism" XP_037292754.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_030034814.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037303356.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_037300055.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037292568.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_030029301.1 5 Reactome: R-HSA-73614;MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73621 "Pyrimidine salvage";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine catabolism" XP_037301908.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_037301396.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030036328.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037299833.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037294807.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_030034166.1 13 Reactome: R-HSA-177504;Reactome: R-HSA-8856825;Reactome: R-HSA-416993;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-8964038;Reactome: R-HSA-2132295;Reactome: R-HSA-8866427;Reactome: R-HSA-437239;Reactome: R-HSA-3928665 "Retrograde neurotrophin signalling";"Cargo recognition for clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"LDL clearance";"MHC class II antigen presentation";"VLDLR internalisation and degradation";"Recycling pathway of L1";"EPH-ephrin mediated repulsion of cells" XP_037294999.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_030020610.2 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_030040724.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037302420.1 6 MetaCyc: PWY-7382;MetaCyc: PWY-6987;KEGG: 00780+6.3.4.15;KEGG: 00785+2.3.1.181;Reactome: R-HSA-3371599;Reactome: R-HSA-196780 "Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin metabolism";"Lipoic acid metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism" XP_030031039.1 10 MetaCyc: PWY-6842;MetaCyc: PWY-7112;MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-8001;MetaCyc: PWY-5826;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061 "Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Glutathione metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I" XP_030020584.1 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_030023418.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_030036596.2 8 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-141444 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_037297201.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518 "Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2" XP_037295033.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030033926.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-6793080 "Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion" XP_030031350.1 3 Reactome: R-HSA-5689877;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395 "Josephin domain DUBs";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER" XP_030031320.1 12 Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-141444 "RHO GTPases Activate Formins";"HCMV Early Events";"Aggrephagy";"Mitotic Prometaphase";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_037293861.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_030041086.2 5 Reactome: R-HSA-427413;KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300;Reactome: R-HSA-4655427;Reactome: R-HSA-5334118 "NoRC negatively regulates rRNA expression";"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins";"DNA methylation" XP_037302922.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_030028339.2 8 Reactome: R-HSA-5362798;Reactome: R-HSA-8941284;Reactome: R-HSA-5658034;Reactome: R-HSA-5632681;Reactome: R-HSA-5635838;Reactome: R-HSA-5358346;Reactome: R-HSA-373080;Reactome: R-HSA-5632684 "Release of Hh-Np from the secreting cell";"RUNX2 regulates chondrocyte maturation";"HHAT G278V abrogates palmitoylation of Hh-Np";"Ligand-receptor interactions";"Activation of SMO";"Hedgehog ligand biogenesis";"Class B/2 (Secretin family receptors)";"Hedgehog 'on' state" XP_030037749.1 4 KEGG: 00860+1.14.14.18;Reactome: R-HSA-917937;Reactome: R-HSA-189483;MetaCyc: PWY-5874 "Porphyrin and chlorophyll metabolism";"Iron uptake and transport";"Heme degradation";"Heme degradation I" XP_037301594.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030022583.2 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037296735.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_030038502.1 5 Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-9609523;Reactome: R-HSA-6807878;Reactome: R-HSA-5694530 "Intra-Golgi traffic";"COPII-mediated vesicle transport";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"COPI-mediated anterograde transport";"Cargo concentration in the ER" XP_030035030.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_030020171.2 34 Reactome: R-HSA-6782210;Reactome: R-HSA-69273;Reactome: R-HSA-167160;Reactome: R-HSA-167162;Reactome: R-HSA-8939236;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-112382;Reactome: R-HSA-73863;Reactome: R-HSA-5696395;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-73776;Reactome: R-HSA-69202;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-69231;Reactome: R-HSA-6782135;Reactome: R-HSA-73762;Reactome: R-HSA-69656;Reactome: R-HSA-76042;Reactome: R-HSA-6781823;Reactome: R-HSA-674695;Reactome: R-HSA-113418 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II HIV Promoter Escape";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Termination";"Formation of Incision Complex in GG-NER";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Promoter Escape";"Cyclin E associated events during G1/S transition";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Cyclin D associated events in G1";"Dual incision in TC-NER";"RNA Polymerase I Transcription Initiation";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex" XP_030037961.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037297963.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706 "Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037300391.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037301336.1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_030034146.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_030029015.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_030032576.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_037297238.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_037301804.1 1 Reactome: R-HSA-2467813 "Separation of Sister Chromatids" XP_030029411.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030021224.2 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_030023790.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037296252.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037297083.1 9 Reactome: R-HSA-3656532;Reactome: R-HSA-3642279;Reactome: R-HSA-5689603;Reactome: R-HSA-3656535;Reactome: R-HSA-3645790;Reactome: R-HSA-3304356;Reactome: R-HSA-2173791;Reactome: R-HSA-2173788;Reactome: R-HSA-2173789 "TGFBR1 KD Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer";"UCH proteinases";"TGFBR1 LBD Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs" XP_030033151.1 4 Reactome: R-HSA-8934903;Reactome: R-HSA-1632852;Reactome: R-HSA-5205685;Reactome: R-HSA-936440 "Receptor Mediated Mitophagy";"Macroautophagy";"Pink/Parkin Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling" XP_030031332.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-3371497 "COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Aggrephagy";"HCMV Early Events";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_030023393.2 9 Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-76042 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_030036755.2 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_030040374.2 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_030033044.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_037301129.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_030032687.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037294165.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_030035181.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_037294412.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway" XP_030024299.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012 "Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_037297935.1 32 Reactome: R-HSA-167242;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167161;Reactome: R-HSA-72165;Reactome: R-HSA-75953;Reactome: R-HSA-167287;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-73776;Reactome: R-HSA-167238;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-168325;Reactome: R-HSA-6803529;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-72203;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-9018519;Reactome: R-HSA-167160;Reactome: R-HSA-167162;Reactome: R-HSA-8851708;Reactome: R-HSA-72163 "Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"HIV Transcription Initiation";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation";"HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"Viral Messenger RNA Synthesis";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Processing of Capped Intron-Containing Pre-mRNA";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II HIV Promoter Escape";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Major Pathway" XP_037299428.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_037293548.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_030033439.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037301355.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_037299414.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037300206.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_030028792.1 10 Reactome: R-HSA-432720;Reactome: R-HSA-9636383;Reactome: R-HSA-8856828;Reactome: R-HSA-9635644;Reactome: R-HSA-8856825;Reactome: R-HSA-917729;Reactome: R-HSA-5689880;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8875360 "Lysosome Vesicle Biogenesis";"Prevention of phagosomal-lysosomal fusion";"Clathrin-mediated endocytosis";"Inhibition of membrane repair";"Cargo recognition for clathrin-mediated endocytosis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Ub-specific processing proteases";"Negative regulation of MET activity";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell" XP_037303160.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_030019702.1 3 Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3;KEGG: 00680+3.1.3.3 "Serine biosynthesis";"Glycine, serine and threonine metabolism";"Methane metabolism" XP_037292706.1 5 Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-75105;Reactome: R-HSA-9029558;Reactome: R-HSA-199220 "Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism" XP_030025575.2 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_037295482.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_030040491.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037294347.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037297412.1 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160 "T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions" XP_037292981.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway" XP_037299987.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_037299584.1 10 Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-5684264;Reactome: R-HSA-2871837;Reactome: R-HSA-2565942;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-5676590 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"FCERI mediated NF-kB activation";"Regulation of PLK1 Activity at G2/M Transition";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling" XP_030033774.1 3 Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597 "Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"G alpha (z) signalling events" XP_030033350.2 5 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-6784531;Reactome: R-HSA-77595 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"tRNA processing in the nucleus";"Processing of Intronless Pre-mRNAs" XP_037303161.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_030035193.2 2 Reactome: R-HSA-1799339;Reactome: R-HSA-6798695 "SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation" XP_037303370.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_030031133.2 1 Reactome: R-HSA-8951664 "Neddylation" XP_030024347.2 24 MetaCyc: PWY-5686;KEGG: 00240+3.5.2.3;MetaCyc: PWY-7400;Reactome: R-HSA-1660662;Reactome: R-HSA-4085001;Reactome: R-HSA-6798695;KEGG: 00240+2.1.3.2;Reactome: R-HSA-2022857;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-5154;KEGG: 00250+2.1.3.2;Reactome: R-HSA-2024096;Reactome: R-HSA-2206308;Reactome: R-HSA-500753;KEGG: 00250+6.3.5.5;MetaCyc: PWY-7790;MetaCyc: PWY-7791;KEGG: 00240+6.3.5.5;KEGG: 00604+3.2.1.23;Reactome: R-HSA-4341670;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23 "UMP biosynthesis I";"Pyrimidine metabolism";"L-arginine biosynthesis IV (archaebacteria)";"Glycosphingolipid metabolism";"Sialic acid metabolism";"Neutrophil degranulation";"Pyrimidine metabolism";"Keratan sulfate degradation";"Galactose metabolism";"Glycosaminoglycan degradation";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"HS-GAG degradation";"MPS IV - Morquio syndrome B";"Pyrimidine biosynthesis";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis II";"UMP biosynthesis III";"Pyrimidine metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Defective NEU1 causes sialidosis";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Sphingolipid metabolism" XP_037296591.1 4 Reactome: R-HSA-422085;KEGG: 00564+3.1.1.7;Reactome: R-HSA-1483191;Reactome: R-HSA-112311 "Synthesis, secretion, and deacylation of Ghrelin";"Glycerophospholipid metabolism";"Synthesis of PC";"Neurotransmitter clearance" XP_030038269.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-983231 "Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production" XP_030025162.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_037292943.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380320 "Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes" XP_030035945.2 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037302528.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism" XP_037298654.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_030025133.2 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_037300915.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_030027543.2 3 Reactome: R-HSA-5368286;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9 "Mitochondrial translation initiation";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate" XP_030028007.2 14 Reactome: R-HSA-2894862;Reactome: R-HSA-1474228;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-6798695;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-9013700;Reactome: R-HSA-977225;Reactome: R-HSA-9017802 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Degradation of the extracellular matrix";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"Neutrophil degranulation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"Noncanonical activation of NOTCH3" XP_037297303.1 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" XP_037298559.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_030041293.1 6 Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-434316 "ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion" XP_030025245.2 2 Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_037301603.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_030028889.2 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_037296472.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_030030222.1 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" XP_037292332.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_030041115.1 57 Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-75815 "Degradation of AXIN";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D" XP_030023810.1 5 KEGG: 00565+2.5.1.26;MetaCyc: PWY-7782;Reactome: R-HSA-9033241;Reactome: R-HSA-75896;Reactome: R-HSA-9033500 "Ether lipid metabolism";"Plasmalogen biosynthesis";"Peroxisomal protein import";"Plasmalogen biosynthesis";"TYSND1 cleaves peroxisomal proteins" XP_030029663.1 4 KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202 "Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines" XP_030029877.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_030029645.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72702 "Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition" XP_030025895.1 31 MetaCyc: PWY-5142;MetaCyc: PWY-7858;MetaCyc: PWY-5989;MetaCyc: PWY-5973;Reactome: R-HSA-75105;MetaCyc: PWYG-321;Reactome: R-HSA-2426168;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-199220;MetaCyc: PWY-7663;MetaCyc: PWY-5366;MetaCyc: PWY-5147;MetaCyc: PWY-5971;MetaCyc: PWY-5994;MetaCyc: PWY-7388;MetaCyc: PWY-8049;Reactome: R-HSA-9029558;MetaCyc: PWY-7723;MetaCyc: PWY-7664;MetaCyc: PWY-4381;MetaCyc: PWY-6799;Reactome: R-HSA-163765;MetaCyc: PWY-6519;MetaCyc: PWY-6282;MetaCyc: PWY-5367;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8012;MetaCyc: PWY-8047;MetaCyc: PWY-7746;MetaCyc: PWY-6113;MetaCyc: PWY-5966-1 "Acyl-[acyl-carrier protein] thioesterase pathway";"(5Z)-dodecenoate biosynthesis II";"Stearate biosynthesis II (bacteria and plants)";"Cis-vaccenate biosynthesis";"Fatty acyl-CoA biosynthesis";"";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Gondoate biosynthesis (anaerobic)";"Palmitoleate biosynthesis II (plants and bacteria)";"Oleate biosynthesis I (plants)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Pederin biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Bacterial bioluminescence";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"ChREBP activates metabolic gene expression";"8-amino-7-oxononanoate biosynthesis I";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Petroselinate biosynthesis";"Biotin metabolism";"Mupirocin biosynthesis";"Bryostatin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Superpathway of mycolate biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)" XP_037300614.1 5 Reactome: R-HSA-73614;Reactome: R-HSA-73621;KEGG: 00983+2.4.2.3;KEGG: 00240+2.4.2.3;MetaCyc: PWY-5532 "Pyrimidine salvage";"Pyrimidine catabolism";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)" XP_037293156.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_030020330.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_030021845.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_030021054.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030041079.2 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_037294082.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_037292349.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037303050.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_030027890.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_037294021.1 11 Reactome: R-HSA-2894862;Reactome: R-HSA-205043;Reactome: R-HSA-1251985;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-193692;Reactome: R-HSA-3928665;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NRIF signals cell death from the nucleus";"Nuclear signaling by ERBB4";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulated proteolysis of p75NTR";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3" XP_030026939.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_037301115.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_030021276.1 12 MetaCyc: PWY-5108;KEGG: 00620+6.2.1.1;MetaCyc: PWY-5132;MetaCyc: PWY-7118;MetaCyc: PWY-6672;KEGG: 00640+6.2.1.1;KEGG: 00680+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00010+6.2.1.1;KEGG: 00630+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-5133 "L-isoleucine biosynthesis V";"Pyruvate metabolism";"Lupulone and humulone biosynthesis";"Chitin degradation to ethanol";"Cis-genanyl-coa degradation";"Propanoate metabolism";"Methane metabolism";"Adlupulone and adhumulone biosynthesis";"Glycolysis / Gluconeogenesis";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Colupulone and cohumulone biosynthesis" XP_030023291.2 9 KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"Thermogenesis";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_030021551.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037296633.1 4 MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;Reactome: R-HSA-156581;MetaCyc: PWY-5041 "2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"Methylation";"S-adenosyl-L-methionine cycle II" XP_037299008.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_030027888.1 7 Reactome: R-HSA-8949613;Reactome: R-HSA-2151201;Reactome: R-HSA-163210;KEGG: 00195+7.1.2.2;Reactome: R-HSA-1268020;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980 "Cristae formation";"Transcriptional activation of mitochondrial biogenesis";"Formation of ATP by chemiosmotic coupling";"Photosynthesis";"Mitochondrial protein import";"Oxidative phosphorylation";"ATP biosynthesis" XP_037302735.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_037299260.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_037292989.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_037299775.1 19 Reactome: R-HSA-4420097;Reactome: R-HSA-525793;Reactome: R-HSA-8964616;Reactome: R-HSA-5627123;Reactome: R-HSA-428543;Reactome: R-HSA-389359;Reactome: R-HSA-5625970;Reactome: R-HSA-418885;Reactome: R-HSA-3928662;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-5663213;Reactome: R-HSA-182971;Reactome: R-HSA-2029482;Reactome: R-HSA-983231;Reactome: R-HSA-5687128;Reactome: R-HSA-8950505;Reactome: R-HSA-114604;Reactome: R-HSA-194840 "VEGFA-VEGFR2 Pathway";"Myogenesis";"G beta:gamma signalling through CDC42";"RHO GTPases activate PAKs";"Inactivation of CDC42 and RAC1";"CD28 dependent Vav1 pathway";"RHO GTPases activate KTN1";"DCC mediated attractive signaling";"EPHB-mediated forward signaling";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"RHO GTPases Activate WASPs and WAVEs";"EGFR downregulation";"Regulation of actin dynamics for phagocytic cup formation";"Factors involved in megakaryocyte development and platelet production";"MAPK6/MAPK4 signaling";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"GPVI-mediated activation cascade";"Rho GTPase cycle" XP_037293893.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030027623.2 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" XP_030037505.2 1 Reactome: R-HSA-110357 "Displacement of DNA glycosylase by APEX1" XP_030027074.2 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_030026778.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_037295376.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037301873.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9633012 "L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_030036542.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_037298979.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_037295641.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_037294941.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037298904.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_037295370.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_037297402.1 3 Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2 "Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway" XP_030029161.1 7 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway" XP_030025618.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030029331.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_037298317.1 13 MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902 "Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Other glycan degradation";"Chitin degradation II (Vibrio)" XP_030030932.1 4 MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;Reactome: R-HSA-72731;MetaCyc: PWY-7174 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Recycling of eIF2:GDP";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" XP_030040986.2 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037299831.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_030025915.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation" XP_030039186.2 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_030024910.1 14 MetaCyc: PWY-1622;MetaCyc: PWY-3841;MetaCyc: PWY-3661-1;MetaCyc: PWY-3661;KEGG: 00630+2.1.2.1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-5497;Reactome: R-HSA-196757;KEGG: 00680+2.1.2.1;KEGG: 00460+2.1.2.1;MetaCyc: PWY-2201;KEGG: 00260+2.1.2.1;MetaCyc: PWY-2161;MetaCyc: PWY-181 "Formaldehyde assimilation I (serine pathway)";"Folate transformations II (plants)";"Glycine betaine degradation II (mammalian)";"Glycine betaine degradation I";"Glyoxylate and dicarboxylate metabolism";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Metabolism of folate and pterines";"Methane metabolism";"Cyanoamino acid metabolism";"Folate transformations I";"Glycine, serine and threonine metabolism";"Folate polyglutamylation";"Photorespiration " XP_037292653.1 7 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway" XP_030026245.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_030033440.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037301821.1 4 MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;Reactome: R-HSA-156581;MetaCyc: PWY-5041 "2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"Methylation";"S-adenosyl-L-methionine cycle II" XP_030029008.1 3 Reactome: R-HSA-6784531;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470 "tRNA processing in the nucleus";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion" XP_037303273.1 5 Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-109704 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"PI3K Cascade" XP_030027442.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037302929.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037295344.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037296957.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_037301147.1 40 Reactome: R-HSA-5578749;Reactome: R-HSA-6781827;Reactome: R-HSA-167290;Reactome: R-HSA-5601884;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-72203;Reactome: R-HSA-77075;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-167172;Reactome: R-HSA-167243;Reactome: R-HSA-9018519;Reactome: R-HSA-6782210;Reactome: R-HSA-8851708;Reactome: R-HSA-72163;Reactome: R-HSA-167162;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167161;Reactome: R-HSA-167287;Reactome: R-HSA-75953;Reactome: R-HSA-72165;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-73776;Reactome: R-HSA-203927;Reactome: R-HSA-167238;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-168325;Reactome: R-HSA-6796648;Reactome: R-HSA-6803529;Reactome: R-HSA-5617472;Reactome: R-HSA-75955 "Transcriptional regulation by small RNAs";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Pausing and recovery of HIV elongation";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"Transcription of the HIV genome";"Tat-mediated HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Major Pathway";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"HIV Transcription Initiation";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Minor Pathway";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Promoter Escape";"MicroRNA (miRNA) biogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"Viral Messenger RNA Synthesis";"TP53 Regulates Transcription of DNA Repair Genes";"FGFR2 alternative splicing";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Transcription Elongation" XP_030020328.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_030025475.2 1 Reactome: R-HSA-8951664 "Neddylation" XP_037294694.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_030031570.1 8 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_037303100.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030023561.2 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037298932.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7725 "Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_030032533.1 7 KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-5628897 "D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes" XP_030030691.1 3 Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007 "Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy" XP_030031403.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_030039554.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_030022495.1 56 Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-4641258;Reactome: R-HSA-174113 "Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1" XP_037300609.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030032574.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_037299382.1 13 KEGG: 00983+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-7533;Reactome: R-HSA-196836;KEGG: 00053+1.8.5.1;KEGG: 00980+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-2261;MetaCyc: PWY-6370;MetaCyc: PWY-7112;MetaCyc: PWY-6842 "Drug metabolism - other enzymes";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Vitamin C (ascorbate) metabolism";"Ascorbate and aldarate metabolism";"Metabolism of xenobiotics by cytochrome P450";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Glutathione metabolism";"Ascorbate glutathione cycle";"Ascorbate recycling (cytosolic)";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II" XP_030024749.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037295630.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037296536.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_030032520.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_037295874.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_030036452.2 2 Reactome: R-HSA-2142691;Reactome: R-HSA-2142700 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)" XP_030040536.2 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_030029169.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037297288.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_030023194.2 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_030022948.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957 "Eukaryotic Translation Termination";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_037303626.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037295427.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_030019962.1 13 MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52 "Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series" XP_030037095.2 7 Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-69205 "Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription" XP_030030891.2 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037294811.1 9 Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-5674135;Reactome: R-HSA-114608;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-6802946 "Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation";"Platelet degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling by moderate kinase activity BRAF mutants" XP_037298726.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_037297584.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase" XP_037302359.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037297585.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase" XP_030026535.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_030025416.2 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_030026502.1 15 Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-9603505;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"NTRK3 as a dependence receptor";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_037301452.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_030019866.2 6 Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1855183;Reactome: R-HSA-1660516;KEGG: 04070+3.1.3.66;MetaCyc: PWY-6368 "Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the early endosome membrane";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation" XP_037295384.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_030019956.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037294890.1 4 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315;KEGG: 00908+2.5.1.75;MetaCyc: PWY-2781 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol";"Zeatin biosynthesis";"Cis-zeatin biosynthesis" XP_030040847.1 6 Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616 "Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_037295100.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_030039534.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-73779 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_037298555.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_030021511.1 2 Reactome: R-HSA-212676;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_037296373.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_030025983.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_030030033.2 1 Reactome: R-HSA-975578 "Reactions specific to the complex N-glycan synthesis pathway" XP_030023465.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037295296.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_030021017.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030024247.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_037294187.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942 "Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition" XP_037301389.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_037301927.1 5 Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-389960 "Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC" XP_030027595.2 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5689880 "UCH proteinases";"Ub-specific processing proteases" XP_030035974.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_037301883.1 5 Reactome: R-HSA-1660662;Reactome: R-HSA-4085001;Reactome: R-HSA-4341670;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295 "Glycosphingolipid metabolism";"Sialic acid metabolism";"Defective NEU1 causes sialidosis";"Neutrophil degranulation";"MHC class II antigen presentation" XP_037298034.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380259 "Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes" XP_030031850.1 4 Reactome: R-HSA-6798695;Reactome: R-HSA-499943;Reactome: R-HSA-2162123;KEGG: 00590+5.3.99.3 "Neutrophil degranulation";"Interconversion of nucleotide di- and triphosphates";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Arachidonic acid metabolism" XP_037301459.1 3 Reactome: R-HSA-381038;Reactome: R-HSA-8957275;Reactome: R-HSA-381426 "XBP1(S) activates chaperone genes";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_030026796.2 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_030025320.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_037299146.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037301650.1 7 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway" XP_030032241.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037300198.1 5 Reactome: R-HSA-5083630;Reactome: R-HSA-350054;Reactome: R-HSA-1912399;Reactome: R-HSA-1912408;Reactome: R-HSA-1912420 "Defective LFNG causes SCDO3";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in Golgi" XP_030025740.1 42 KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-6945;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;MetaCyc: PWY-1361;MetaCyc: PWY-6435;KEGG: 00410+4.2.1.17;MetaCyc: PWY-5136;MetaCyc: PWY-7778;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;MetaCyc: PWY-6883;MetaCyc: PWY-6583;MetaCyc: PWY-5177;MetaCyc: PWY-7401;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;MetaCyc: PWY-7094;MetaCyc: PWY-7726;MetaCyc: PWY-6863;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;MetaCyc: PWY-6946;KEGG: 00903+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;MetaCyc: PWY-5138;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6944;MetaCyc: PWY-7654;MetaCyc: PWY-5109;KEGG: 00360+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35 "Fatty acid elongation";"Toluene degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Valine, leucine and isoleucine degradation";"Propanoate metabolism";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fatty acid degradation";"Methyl tert-butyl ether degradation";"Benzoyl-coa degradation I (aerobic)";"4-hydroxybenzoate biosynthesis III (plants)";"beta-Alanine metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"2-methylpropene degradation";"Tryptophan metabolism";"Fatty acid degradation";"Carbon fixation pathways in prokaryotes";"alpha-Linolenic acid metabolism";"Lysine degradation";"Methyl ketone biosynthesis (engineered)";"Pyruvate fermentation to butanol II (engineered)";"Pyruvate fermentation to butanol I";"Glutaryl-coa degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Butanoate metabolism";"Spodoptera littoralis pheromone biosynthesis";"Fatty acid salvage";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Pyruvate fermentation to hexanol (engineered)";"Geraniol degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Limonene and pinene degradation";"Caprolactam degradation";"Butanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Aminobenzoate degradation";"Androstenedione degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fermentation to 2-methylbutanoate";"Phenylalanine metabolism";"Benzoate degradation" XP_037303006.1 24 Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-190840 "Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"Recycling pathway of L1";"Mitotic Prometaphase";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane" XP_037296908.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-429958 "Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease" XP_030038785.1 3 Reactome: R-HSA-3108214;Reactome: R-HSA-164843;Reactome: R-HSA-5693571 "SUMOylation of DNA damage response and repair proteins";"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)" XP_030025866.1 2 Reactome: R-HSA-1566948;Reactome: R-HSA-2243919 "Elastic fibre formation";"Crosslinking of collagen fibrils" XP_037294447.1 12 Reactome: R-HSA-1839117;KEGG: 05170+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5655302;KEGG: 05165+2.7.11.1 "Signaling by cytosolic FGFR1 fusion mutants";"Human immunodeficiency virus 1 infection";"Rho GTPase cycle";"Thermogenesis";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"mTOR signaling pathway";"Relaxin signaling pathway";"NRAGE signals death through JNK";"PI3K-Akt signaling pathway";"Signaling by FGFR1 in disease";"Human papillomavirus infection" XP_037297359.1 2 Reactome: R-HSA-3000178;MetaCyc: PWY-7511 "ECM proteoglycans";"Protein ubiquitination" XP_037297186.1 3 Reactome: R-HSA-2024101;Reactome: R-HSA-2024096;Reactome: R-HSA-2206296 "CS/DS degradation";"HS-GAG degradation";"MPS II - Hunter syndrome" XP_037301362.1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_037302775.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037299169.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_030024342.2 8 MetaCyc: PWY-7400;MetaCyc: PWY-5;MetaCyc: PWY-4983;MetaCyc: PWY-5154;KEGG: 00250+4.3.2.1;KEGG: 00220+4.3.2.1;Reactome: R-HSA-70635;MetaCyc: PWY-4984 "L-arginine biosynthesis IV (archaebacteria)";"Canavanine biosynthesis";"Nitric oxide biosynthesis II (mammals)";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Urea cycle";"Urea cycle" XP_037292669.1 4 MetaCyc: PWY-6922;Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737 "L-Ndelta-acetylornithine biosynthesis";"Proline catabolism";"Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis" XP_030032747.2 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_030021513.1 5 MetaCyc: PWY-6121;MetaCyc: PWY-6122;MetaCyc: PWY-6277;Reactome: R-HSA-73817;KEGG: 00230+6.3.5.3 "5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism" XP_037298520.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037295172.1 13 KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822 "Other glycan degradation";"Chitin degradation II (Vibrio)";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"CS/DS degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)" XP_037296725.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_030034486.2 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_037294191.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380320 "Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes" XP_030037880.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030033030.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_030035976.1 1 MetaCyc: PWY-6938 "NADH repair" XP_030037747.1 2 Reactome: R-HSA-1237112;Reactome: R-HSA-8950505 "Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_030032646.2 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037297372.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_030040498.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_030027245.1 5 Reactome: R-HSA-8957275;Reactome: R-HSA-879415;Reactome: R-HSA-901042;Reactome: R-HSA-381426;Reactome: R-HSA-532668 "Post-translational protein phosphorylation";"Advanced glycosylation endproduct receptor signaling";"Calnexin/calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_037295918.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_030035955.1 17 Reactome: R-HSA-6804756;Reactome: R-HSA-5685939;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-3270619;Reactome: R-HSA-1834949;Reactome: R-HSA-912446;Reactome: R-HSA-5693548;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554 "Regulation of TP53 Activity through Phosphorylation";"HDR through MMEJ (alt-NHEJ)";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA";"Meiotic recombination";"Sensing of DNA Double Strand Breaks";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_030040733.1 5 Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-174490 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins" XP_030030716.2 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_030024894.2 10 Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-6804756 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation" XP_037299462.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_030021887.2 3 Reactome: R-HSA-9634638;Reactome: R-HSA-525793;Reactome: R-HSA-5663220 "Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis";"RHO GTPases Activate Formins" XP_037301783.1 6 Reactome: R-HSA-201722;Reactome: R-HSA-8866654;Reactome: R-HSA-5632684;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of the beta-catenin:TCF transactivating complex";"E3 ubiquitin ligases ubiquitinate target proteins";"Hedgehog 'on' state";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_030036050.1 6 Reactome: R-HSA-5617472;Reactome: R-HSA-8951664;Reactome: R-HSA-3769402;Reactome: R-HSA-3214841;Reactome: R-HSA-201722;Reactome: R-HSA-8936459 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Neddylation";"Deactivation of the beta-catenin transactivating complex";"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_030022082.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-164378 "Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"G alpha (i) signalling events";"Purine metabolism";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling" XP_030024586.2 3 Reactome: R-HSA-381038;Reactome: R-HSA-8957275;Reactome: R-HSA-381426 "XBP1(S) activates chaperone genes";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_030034845.2 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_037297392.1 27 Reactome: R-HSA-4615885;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638 "SUMOylation of DNA replication proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins" XP_030036659.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037296939.1 7 MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-5461;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7 "Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis" XP_037294670.1 5 Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-201681;MetaCyc: PWY-7511;Reactome: R-HSA-5689880 "Degradation of AXIN";"Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT";"Protein ubiquitination";"Ub-specific processing proteases" XP_037301462.1 2 KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" XP_037292286.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_030037737.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037292257.1 7 KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_037294404.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862 "Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_030021646.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_030031771.1 7 MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-7214 "Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)" XP_037301904.1 10 MetaCyc: PWY-6537;Reactome: R-HSA-916853;MetaCyc: PWY-4321;KEGG: 00640+2.6.1.19;KEGG: 00410+2.6.1.19;MetaCyc: PWY-6535;KEGG: 00650+2.6.1.19;MetaCyc: PWY-5022;KEGG: 00250+2.6.1.19;MetaCyc: PWY-6536 "4-aminobutanoate degradation II";"Degradation of GABA";"L-glutamate degradation IV";"Propanoate metabolism";"beta-Alanine metabolism";"4-aminobutanoate degradation I";"Butanoate metabolism";"4-aminobutanoate degradation V";"Alanine, aspartate and glutamate metabolism";"4-aminobutanoate degradation III" XP_037299664.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_030040316.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_037297415.1 3 Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2 "Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway" XP_037303306.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037295861.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_030031311.2 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_037297910.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_030031105.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030021629.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-9609523;Reactome: R-HSA-1660661 "Neutrophil degranulation";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Sphingolipid de novo biosynthesis" XP_037297234.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_030023654.2 5 Reactome: R-HSA-432720;KEGG: 00531+3.1.6.14;Reactome: R-HSA-2206305;Reactome: R-HSA-6798695;Reactome: R-HSA-2022857 "Lysosome Vesicle Biogenesis";"Glycosaminoglycan degradation";"MPS IIID - Sanfilippo syndrome D";"Neutrophil degranulation";"Keratan sulfate degradation" XP_030033366.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_030035265.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_037298002.1 5 Reactome: R-HSA-4341670;Reactome: R-HSA-1660662;Reactome: R-HSA-4085001;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295 "Defective NEU1 causes sialidosis";"Glycosphingolipid metabolism";"Sialic acid metabolism";"Neutrophil degranulation";"MHC class II antigen presentation" XP_037297336.1 2 Reactome: R-HSA-2408508;Reactome: R-HSA-389661 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation" XP_030023787.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_030021977.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" XP_030030620.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037300777.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_030025355.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_030035735.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_037300535.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_030034363.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6783310 "Protein ubiquitination";"Fanconi Anemia Pathway" XP_037295014.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_037302920.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_030035381.2 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037302676.1 3 KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161;Reactome: R-HSA-196757 "Folate biosynthesis";"Folate polyglutamylation";"Metabolism of folate and pterines" XP_030025084.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_030032272.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_030023073.1 4 Reactome: R-HSA-3371568;Reactome: R-HSA-9018519;Reactome: R-HSA-3371497;Reactome: R-HSA-8939211 "Attenuation phase";"Estrogen-dependent gene expression";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"ESR-mediated signaling" XP_030032672.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_030032122.1 4 Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_030030681.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_030028939.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037300984.1 5 MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822 "Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)" XP_030023776.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_030033709.2 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" XP_037297405.1 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097 "T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway" XP_037302062.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_037299440.1 18 Reactome: R-HSA-6783984;KEGG: 00020+1.8.1.4;Reactome: R-HSA-70268;MetaCyc: PWY-5084;KEGG: 00310+1.8.1.4;Reactome: R-HSA-70895;KEGG: 00380+1.8.1.4;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;Reactome: R-HSA-389661;Reactome: R-HSA-71403;KEGG: 00620+1.8.1.4;Reactome: R-HSA-71064;KEGG: 00280+1.8.1.4;KEGG: 00010+1.8.1.4;MetaCyc: PWY-5046;KEGG: 00640+1.8.1.4;KEGG: 00260+1.8.1.4 "Glycine degradation";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Branched-chain amino acid catabolism";"Tryptophan metabolism";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Citric acid cycle (TCA cycle)";"Pyruvate metabolism";"Lysine catabolism";"Valine, leucine and isoleucine degradation";"Glycolysis / Gluconeogenesis";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Propanoate metabolism";"Glycine, serine and threonine metabolism" XP_030021628.1 3 Reactome: R-HSA-1660661;Reactome: R-HSA-9609523;Reactome: R-HSA-6798695 "Sphingolipid de novo biosynthesis";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Neutrophil degranulation" XP_037297274.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_037299774.1 19 Reactome: R-HSA-182971;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-114604;Reactome: R-HSA-8950505;Reactome: R-HSA-5687128;Reactome: R-HSA-194840;Reactome: R-HSA-983231;Reactome: R-HSA-525793;Reactome: R-HSA-4420097;Reactome: R-HSA-389359;Reactome: R-HSA-5625970;Reactome: R-HSA-418885;Reactome: R-HSA-8964616;Reactome: R-HSA-5627123;Reactome: R-HSA-428543 "EGFR downregulation";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"GPVI-mediated activation cascade";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"MAPK6/MAPK4 signaling";"Rho GTPase cycle";"Factors involved in megakaryocyte development and platelet production";"Myogenesis";"VEGFA-VEGFR2 Pathway";"CD28 dependent Vav1 pathway";"RHO GTPases activate KTN1";"DCC mediated attractive signaling";"G beta:gamma signalling through CDC42";"RHO GTPases activate PAKs";"Inactivation of CDC42 and RAC1" XP_037292842.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_037297535.1 6 MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism" XP_037297021.1 11 MetaCyc: PWY-882;KEGG: 00520+5.3.1.8;MetaCyc: PWY-7456;MetaCyc: PWY-3881;Reactome: R-HSA-4043916;MetaCyc: PWY-5659;MetaCyc: PWY-3861;Reactome: R-HSA-446205;MetaCyc: PWY-6992;MetaCyc: PWY-7586;KEGG: 00051+5.3.1.8 "L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation";"Mannitol biosynthesis";"Defective MPI causes MPI-CDG (CDG-1b)";"GDP-mannose biosynthesis";"Mannitol degradation II";"Synthesis of GDP-mannose";"1,5-anhydrofructose degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Fructose and mannose metabolism" XP_030023867.2 1 Reactome: R-HSA-1614558 "Degradation of cysteine and homocysteine" XP_030033273.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_030040665.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_037299053.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_030035609.2 5 KEGG: 00330+1.2.1.88;Reactome: R-HSA-389661;Reactome: R-HSA-70688;KEGG: 00250+1.2.1.88;MetaCyc: PWY-6853 "Arginine and proline metabolism";"Glyoxylate metabolism and glycine degradation";"Proline catabolism";"Alanine, aspartate and glutamate metabolism";"Ethylene biosynthesis II (microbes)" XP_030034070.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_030023804.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030023122.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037299092.1 12 Reactome: R-HSA-5620912;Reactome: R-HSA-2132295;Reactome: R-HSA-8854518;Reactome: R-HSA-381038;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284 "Anchoring of the basal body to the plasma membrane";"MHC class II antigen presentation";"AURKA Activation by TPX2";"XBP1(S) activates chaperone genes";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_037295501.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_030030729.2 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_030026322.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_030037561.1 15 Reactome: R-HSA-1660499;Reactome: R-HSA-416476;Reactome: R-HSA-912526;Reactome: R-HSA-389357;Reactome: R-HSA-8853659;Reactome: R-HSA-1433557;Reactome: R-HSA-512988;Reactome: R-HSA-1257604;Reactome: R-HSA-388841;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-114604;Reactome: R-HSA-1266695;Reactome: R-HSA-9009391;Reactome: R-HSA-912631 "Synthesis of PIPs at the plasma membrane";"G alpha (q) signalling events";"Interleukin receptor SHC signaling";"CD28 dependent PI3K/Akt signaling";"RET signaling";"Signaling by SCF-KIT";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"PIP3 activates AKT signaling";"Costimulation by the CD28 family";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"GPVI-mediated activation cascade";"Interleukin-7 signaling";"Extra-nuclear estrogen signaling";"Regulation of signaling by CBL" XP_030029439.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037295887.1 8 KEGG: 00190+7.1.2.2;Reactome: R-HSA-917977;MetaCyc: PWY-7980;Reactome: R-HSA-77387;KEGG: 00195+7.1.2.2;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556 "Oxidative phosphorylation";"Transferrin endocytosis and recycling";"ATP biosynthesis";"Insulin receptor recycling";"Photosynthesis";"Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes" XP_030034077.2 17 Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-8853884;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-174048;Reactome: R-HSA-176412;Reactome: R-HSA-141430 "CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Transcriptional Regulation by VENTX";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex" XP_030037903.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_030032242.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_030029316.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_030033626.1 3 MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6 "Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism" XP_030032754.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_037302686.1 33 Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-141444;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-2500257;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-170822 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"Mitotic Prometaphase";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"RHO GTPases Activate Formins";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"Resolution of Sister Chromatid Cohesion";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"Viral Messenger RNA Synthesis";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein" XP_037303571.1 12 Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-8941856;Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-73762;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-5250924;Reactome: R-HSA-3214847;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695 "NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"RNA Polymerase I Transcription Initiation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"B-WICH complex positively regulates rRNA expression";"HATs acetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription" XP_037298757.1 11 Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-170670 "PKA activation in glucagon signalling";"G alpha (i) signalling events";"PKA activation";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"Hedgehog 'off' state";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway" XP_037294369.1 3 Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_037293473.1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway" XP_030023060.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037295447.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_030038706.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_030041116.1 8 Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-174430 "DNA replication initiation";"Polymerase switching";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation" XP_030032634.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_037296125.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_037294300.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_030028897.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030032189.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030038963.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030023330.2 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_037298813.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_030020493.2 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_030021631.1 3 Reactome: R-HSA-1660661;Reactome: R-HSA-9609523;Reactome: R-HSA-6798695 "Sphingolipid de novo biosynthesis";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Neutrophil degranulation" XP_037302962.1 5 KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22 "Galactose metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Glycerolipid metabolism" XP_037300886.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_037301680.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037294626.1 33 Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-141444;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-9648025;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-2467813 "NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Mitotic Prometaphase";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"EML4 and NUDC in mitotic spindle formation";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"Separation of Sister Chromatids" XP_037292351.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030031468.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_037303441.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037298558.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037293689.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_030023118.1 9 MetaCyc: PWY-5789;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-241;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-5743;Reactome: R-HSA-1475029 "3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide" XP_030031061.2 10 KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11;MetaCyc: PWY-7385;MetaCyc: PWY-5484 "Methane metabolism";"Pentose phosphate pathway";"Galactose metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)" XP_037300504.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030024346.2 11 MetaCyc: PWY-5154;KEGG: 00240+6.3.5.5;KEGG: 00250+2.1.3.2;KEGG: 00240+3.5.2.3;MetaCyc: PWY-7400;MetaCyc: PWY-5686;Reactome: R-HSA-500753;KEGG: 00250+6.3.5.5;MetaCyc: PWY-7791;KEGG: 00240+2.1.3.2;MetaCyc: PWY-7790 "L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis I";"Pyrimidine biosynthesis";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis III";"Pyrimidine metabolism";"UMP biosynthesis II" XP_030037106.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_030027070.2 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" XP_030038569.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_030026539.2 11 Reactome: R-HSA-1660516;Reactome: R-HSA-1660514;KEGG: 00562+2.7.1.137;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660517;Reactome: R-HSA-168138;Reactome: R-HSA-5668599;MetaCyc: PWY-6352;Reactome: R-HSA-1632852;Reactome: R-HSA-109704;Reactome: R-HSA-1660499 "Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the late endosome membrane";"Toll Like Receptor 9 (TLR9) Cascade";"RHO GTPases Activate NADPH Oxidases";"3-phosphoinositide biosynthesis";"Macroautophagy";"PI3K Cascade";"Synthesis of PIPs at the plasma membrane" XP_030034058.2 6 Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-176974 "Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Unwinding of DNA" XP_030027455.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_030020023.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037298982.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_037298660.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_030020072.1 5 Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_030032922.2 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_030020066.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_030032927.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_030021675.1 1 Reactome: R-HSA-189451 "Heme biosynthesis" XP_030037486.2 1 Reactome: R-HSA-8951664 "Neddylation" XP_030035984.1 6 Reactome: R-HSA-6804759;Reactome: R-HSA-6803205;Reactome: R-HSA-139915;Reactome: R-HSA-6803211;Reactome: R-HSA-6803204;Reactome: R-HSA-6803207 "Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Caspase Activators and Caspases" XP_030033232.2 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_037299947.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_037298098.1 14 Reactome: R-HSA-418217;MetaCyc: PWY-6367;Reactome: R-HSA-399997;Reactome: R-HSA-416476;KEGG: 04070+3.1.4.11;Reactome: R-HSA-434316;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-500657;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;MetaCyc: PWY-8052;Reactome: R-HSA-4086398;KEGG: 00562+3.1.4.11 "G beta:gamma signalling through PLC beta";"D-myo-inositol-5-phosphate metabolism";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"Phosphatidylinositol signaling system";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Presynaptic function of Kainate receptors";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis";"Ca2+ pathway";"Inositol phosphate metabolism" XP_037295377.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037294642.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-8041;Reactome: R-HSA-75876 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs" XP_030040727.1 24 Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"Recycling pathway of L1";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids" XP_030019967.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_037293614.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_030022806.1 1 Reactome: R-HSA-427359 "SIRT1 negatively regulates rRNA expression" XP_030021506.1 18 Reactome: R-HSA-5362517;KEGG: 00310+1.8.1.4;Reactome: R-HSA-70895;KEGG: 00380+1.8.1.4;Reactome: R-HSA-70268;MetaCyc: PWY-5084;Reactome: R-HSA-6783984;KEGG: 00020+1.8.1.4;KEGG: 00010+1.8.1.4;KEGG: 00640+1.8.1.4;MetaCyc: PWY-5046;KEGG: 00260+1.8.1.4;Reactome: R-HSA-71064;KEGG: 00280+1.8.1.4;KEGG: 00620+1.8.1.4;Reactome: R-HSA-204174;Reactome: R-HSA-71403;Reactome: R-HSA-389661 "Signaling by Retinoic Acid";"Lysine degradation";"Branched-chain amino acid catabolism";"Tryptophan metabolism";"Pyruvate metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glycine degradation";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Propanoate metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glycine, serine and threonine metabolism";"Lysine catabolism";"Valine, leucine and isoleucine degradation";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Citric acid cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation" XP_037298122.1 2 Reactome: R-HSA-6811436;Reactome: R-HSA-8876198 "COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_037295585.1 10 KEGG: 04151+2.7.1.153;KEGG: 00562+2.7.1.153;KEGG: 05170+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 04150+2.7.1.153;MetaCyc: PWY-6352;KEGG: 04070+2.7.1.153;KEGG: 05163+2.7.1.153;KEGG: 05165+2.7.1.153;Reactome: R-HSA-1660499 "PI3K-Akt signaling pathway";"Inositol phosphate metabolism";"Human immunodeficiency virus 1 infection";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"mTOR signaling pathway";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Human cytomegalovirus infection";"Human papillomavirus infection";"Synthesis of PIPs at the plasma membrane" XP_030029218.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_030023955.2 12 Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-1169408;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-429947;Reactome: R-HSA-72649;Reactome: R-HSA-72662;Reactome: R-HSA-450408;Reactome: R-HSA-156827;Reactome: R-HSA-166208 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"ISG15 antiviral mechanism";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Deadenylation of mRNA";"Translation initiation complex formation";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"mTORC1-mediated signalling" XP_037292915.1 7 KEGG: 00010+2.3.1.12;Reactome: R-HSA-389661;KEGG: 00620+2.3.1.12;KEGG: 00020+2.3.1.12;Reactome: R-HSA-204174;Reactome: R-HSA-70268;Reactome: R-HSA-5362517 "Glycolysis / Gluconeogenesis";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Signaling by Retinoic Acid" XP_030025118.2 7 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-606279;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Deposition of new CENPA-containing nucleosomes at the centromere";"EML4 and NUDC in mitotic spindle formation" XP_030034740.2 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_030036151.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_030034641.2 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_030021473.1 5 Reactome: R-HSA-5620924;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-983189 "Intraflagellar transport";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins" XP_030029070.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339 "Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane" XP_030040393.2 2 MetaCyc: PWY-7802;MetaCyc: PWY-7799 "N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)" YP_001650755.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_030040301.2 1 Reactome: R-HSA-9616222 "Transcriptional regulation of granulopoiesis" XP_030027292.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_030038893.1 3 Reactome: R-HSA-174403;MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7 "Glutathione synthesis and recycling";"5-oxo-L-proline metabolism";"Glutathione metabolism" XP_030021772.1 19 Reactome: R-HSA-8856825;Reactome: R-HSA-5686938;Reactome: R-HSA-3000497;Reactome: R-HSA-8866423;Reactome: R-HSA-3000471;Reactome: R-HSA-8964046;Reactome: R-HSA-975634;Reactome: R-HSA-3000484;Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-8856828;Reactome: R-HSA-8963888;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-3000480;Reactome: R-HSA-8964026;Reactome: R-HSA-8963901;Reactome: R-HSA-8964041;Reactome: R-HSA-202733 "Cargo recognition for clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"Scavenging by Class H Receptors";"VLDL assembly";"Scavenging by Class B Receptors";"VLDL clearance";"Retinoid metabolism and transport";"Scavenging by Class F Receptors";"Platelet sensitization by LDL";"LDL clearance";"Clathrin-mediated endocytosis";"Chylomicron assembly";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class A Receptors";"Chylomicron clearance";"Chylomicron remodeling";"LDL remodeling";"Cell surface interactions at the vascular wall" XP_030020161.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037301205.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_037297032.1 7 MetaCyc: PWY-5461;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-7214 "Betanidin degradation";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)" XP_037294030.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037298047.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037299376.1 6 Reactome: R-HSA-9022692;Reactome: R-HSA-9609690;Reactome: R-HSA-3214815;Reactome: R-HSA-1989781;Reactome: R-HSA-9029569;Reactome: R-HSA-9022537 "Regulation of MECP2 expression and activity";"HCMV Early Events";"HDACs deacetylate histones";"PPARA activates gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Loss of MECP2 binding ability to the NCoR/SMRT complex" XP_037300707.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_030021480.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-1660499;Reactome: R-HSA-8873719;Reactome: R-HSA-6798695;Reactome: R-HSA-8876198 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Synthesis of PIPs at the plasma membrane";"RAB geranylgeranylation";"Neutrophil degranulation";"RAB GEFs exchange GTP for GDP on RABs" XP_037296935.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037297559.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030024413.1 2 Reactome: R-HSA-8849175;KEGG: 00260+2.3.1.29 "Threonine catabolism";"Glycine, serine and threonine metabolism" XP_030030092.2 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_030035394.1 6 Reactome: R-HSA-9033241;Reactome: R-HSA-6798695;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;KEGG: 00630+1.11.1.6;KEGG: 00380+1.11.1.6 "Peroxisomal protein import";"Neutrophil degranulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Glyoxylate and dicarboxylate metabolism";"Tryptophan metabolism" XP_030033279.1 6 KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-7234;MetaCyc: PWY-6124;KEGG: 00670+2.1.2.3;Reactome: R-HSA-73817;MetaCyc: PWY-6123 "Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II";"One carbon pool by folate";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I" XP_030028338.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030034990.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_037298823.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_030028271.2 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_037299319.1 12 MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-6803 "Anandamide biosynthesis I";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing" XP_037299829.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_030027055.2 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037301282.1 1 KEGG: 00290+4.2.1.33 "Valine, leucine and isoleucine biosynthesis" XP_037293454.1 7 KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection" XP_037292645.1 6 MetaCyc: PWY-7391;MetaCyc: PWY-6174;MetaCyc: PWY-922;Reactome: R-HSA-2426168;KEGG: 00900+2.7.1.36;Reactome: R-HSA-191273 "Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis" XP_037297519.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_030024410.2 7 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-606279;Reactome: R-HSA-5663220 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"RHO GTPases Activate Formins" XP_037296183.1 1 Reactome: R-HSA-437239 "Recycling pathway of L1" XP_030020545.1 4 Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin" XP_037297109.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_037294414.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862 "Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_037292456.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_037293938.1 4 Reactome: R-HSA-937039;Reactome: R-HSA-9020702;MetaCyc: PWY-7511;Reactome: R-HSA-975144 "IRAK1 recruits IKK complex";"Interleukin-1 signaling";"Protein ubiquitination";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation" XP_030028226.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_030028096.2 5 Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-6814122 "Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_030036539.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_030025148.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_037295528.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73776 "Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape" XP_030029395.1 4 KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;Reactome: R-HSA-499943;MetaCyc: PWY-7221 "Purine metabolism";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis" XP_030022484.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037294652.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_030022115.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_030030837.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" XP_030033661.1 3 KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596 "Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I" XP_037303482.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_030040329.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_037299011.1 5 Reactome: R-HSA-5675221;Reactome: R-HSA-112409;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "Negative regulation of MAPK pathway";"RAF-independent MAPK1/3 activation";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_030024961.1 16 Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-2559580;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-8936459;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723 "Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"Oxidative Stress Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation" XP_037302440.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030022007.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_030029335.1 3 Reactome: R-HSA-8963684;KEGG: 00350+1.13.11.5;KEGG: 00643+1.13.11.5 "Tyrosine catabolism";"Tyrosine metabolism";"Styrene degradation" XP_037293055.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_037292751.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_030022963.2 6 Reactome: R-HSA-6798695;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135 "Neutrophil degranulation";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER" XP_037299179.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037295755.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030022800.1 1 Reactome: R-HSA-191273 "Cholesterol biosynthesis" XP_037301023.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_037298679.1 7 Reactome: R-HSA-5362798;Reactome: R-HSA-5635838;Reactome: R-HSA-5658034;Reactome: R-HSA-373080;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-5632681 "Release of Hh-Np from the secreting cell";"Activation of SMO";"HHAT G278V abrogates palmitoylation of Hh-Np";"Class B/2 (Secretin family receptors)";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Ligand-receptor interactions" XP_030028109.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-5625970 "COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Kinesins";"RHO GTPases activate KTN1" XP_030031379.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_030023774.2 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037294457.1 13 Reactome: R-HSA-6802952;Reactome: R-HSA-5674135;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6802948;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6802946;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;KEGG: 04926+2.7.11.1 "Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Signaling by high-kinase activity BRAF mutants";"PI3K-Akt signaling pathway";"Signaling by moderate kinase activity BRAF mutants";"Human papillomavirus infection";"mTOR signaling pathway";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Relaxin signaling pathway" XP_030025309.2 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_030031423.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_037296023.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_030024886.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_030020922.1 15 MetaCyc: PWY-8004;KEGG: 00620+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-6142;MetaCyc: PWY-7003;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-7218;KEGG: 00230+2.7.1.40;MetaCyc: PWY-5723;MetaCyc: PWY-6886 "Entner-Doudoroff pathway I";"Pyruvate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Purine metabolism";"Rubisco shunt";"1-butanol autotrophic biosynthesis (engineered)" XP_030025165.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_037301385.1 4 Reactome: R-HSA-9018519;Reactome: R-HSA-8939211;Reactome: R-HSA-3371497;Reactome: R-HSA-3371568 "Estrogen-dependent gene expression";"ESR-mediated signaling";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Attenuation phase" XP_037293403.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_030021721.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_030024030.1 10 MetaCyc: PWY-6362;KEGG: 04070+2.7.1.159;MetaCyc: PWY-6554;KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-6365;Reactome: R-HSA-983231;Reactome: R-HSA-1855167;MetaCyc: PWY-6366;Reactome: R-HSA-1855204;MetaCyc: PWY-4661 "1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol phosphate metabolism";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"Factors involved in megakaryocyte development and platelet production";"Synthesis of pyrophosphates in the cytosol";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)" XP_037300272.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_037302777.1 5 Reactome: R-HSA-204005;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPII-mediated vesicle transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_030032198.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_030031326.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-3371497 "COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"HCMV Early Events";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_030040326.1 3 KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317 "Glycolysis / Gluconeogenesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)" XP_030040022.2 7 MetaCyc: PWY-7158;KEGG: 00400+1.14.16.1;Reactome: R-HSA-8964208;MetaCyc: PWY-6134;KEGG: 00360+1.14.16.1;KEGG: 00790+1.14.16.1;Reactome: R-HSA-2160456 "L-phenylalanine degradation V";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism";"L-tyrosine biosynthesis IV";"Phenylalanine metabolism";"Folate biosynthesis";"Phenylketonuria" XP_037298507.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030032150.2 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_030030687.1 3 KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646;Reactome: R-HSA-5579007 "Arginine biosynthesis";"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy" XP_037292598.1 12 KEGG: 00680+4.1.2.13;Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-1042;KEGG: 00030+4.1.2.13;KEGG: 00010+4.1.2.13;MetaCyc: PWY-1861;KEGG: 00710+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-7385;MetaCyc: PWY-5484;KEGG: 00051+4.1.2.13 "Methane metabolism";"Gluconeogenesis";"Glycolysis";"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism" XP_030036747.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9010553 "Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs" XP_030031450.2 9 Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-3928662;Reactome: R-HSA-438066;Reactome: R-HSA-6794361;Reactome: R-HSA-5673001 "Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"EPHB-mediated forward signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"Neurexins and neuroligins";"RAF/MAP kinase cascade" XP_037293868.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_030028149.1 30 Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-2644607;Reactome: R-HSA-202424;Reactome: R-HSA-9604323;Reactome: R-HSA-2894862;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-69231;Reactome: R-HSA-187577;Reactome: R-HSA-2644606;Reactome: R-HSA-1169091;Reactome: R-HSA-2565942;Reactome: R-HSA-1170546;Reactome: R-HSA-5607764;Reactome: R-HSA-2122947;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-400253;Reactome: R-HSA-917937;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-5684264;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-68949 "Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Downstream TCR signaling";"Negative regulation of NOTCH4 signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Cyclin D associated events in G1";"SCF(Skp2)-mediated degradation of p27/p21";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activation of NF-kappaB in B cells";"Regulation of PLK1 Activity at G2/M Transition";"Prolactin receptor signaling";"CLEC7A (Dectin-1) signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Circadian Clock";"Iron uptake and transport";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin" XP_037299365.1 14 MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-5972 "Juniperonate biosynthesis";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)" XP_030022893.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037294276.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_030035020.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037301247.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_030019887.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030039016.1 2 Reactome: R-HSA-532668;Reactome: R-HSA-6798695 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation" XP_030040629.1 7 Reactome: R-HSA-71336;MetaCyc: PWY-8004;KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514;KEGG: 00030+3.1.1.31;MetaCyc: PWY-6906;MetaCyc: PWY-6855 "Pentose phosphate pathway";"Entner-Doudoroff pathway I";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Pentose phosphate pathway";"Chitin derivatives degradation";"Chitin degradation I (archaea)" XP_030028839.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_030023693.2 5 KEGG: 00670+1.5.1.20;MetaCyc: PWY-2201;MetaCyc: PWY-3841;KEGG: 00720+1.5.1.20;Reactome: R-HSA-196757 "One carbon pool by folate";"Folate transformations I";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines" XP_037299478.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_030041078.2 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_030029413.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037293488.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_030030329.1 2 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine, serine and threonine metabolism" XP_030023155.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037293997.1 22 Reactome: R-HSA-5358749;Reactome: R-HSA-432142;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5467337;Reactome: R-HSA-196299;Reactome: R-HSA-5673000;Reactome: R-HSA-5358752;Reactome: R-HSA-5358747;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-5467340;Reactome: R-HSA-6811558;Reactome: R-HSA-195253;Reactome: R-HSA-5467348;Reactome: R-HSA-141444;Reactome: R-HSA-389513;Reactome: R-HSA-5675221;Reactome: R-HSA-4641262 "S37 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"APC truncation mutants have impaired AXIN binding";"Beta-catenin phosphorylation cascade";"RAF activation";"T41 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"AXIN missense mutants destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Degradation of beta-catenin by the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"CTLA4 inhibitory signaling";"Negative regulation of MAPK pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane" XP_037300140.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037292694.1 8 Reactome: R-HSA-74217;MetaCyc: PWY-6611;Reactome: R-HSA-5683826;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;MetaCyc: PWY-7179;Reactome: R-HSA-6798695 "Purine salvage";"Adenine and adenosine salvage V";"Surfactant metabolism";"Purine metabolism";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation I";"Neutrophil degranulation" XP_030029084.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_037298933.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_030020077.1 5 Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828 "InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"Clathrin-mediated endocytosis" XP_030020417.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_037295512.1 7 Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_030027079.1 5 MetaCyc: PWY-7817;MetaCyc: PWY-5981;MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41 "Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system" XP_030032163.1 2 Reactome: R-HSA-2206307;Reactome: R-HSA-2024096 "MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation" XP_037293760.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_030031083.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_030030624.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037296906.1 6 KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;MetaCyc: PWY-7817 "Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_030020555.1 3 KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823;Reactome: R-HSA-947581 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_037301267.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030034984.1 14 MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5080 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I" XP_037295969.1 1 Reactome: R-HSA-70350 "Fructose catabolism" XP_030020579.2 12 Reactome: R-HSA-9620244;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-447038;Reactome: R-HSA-8849932;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-451308;Reactome: R-HSA-438066;MetaCyc: PWY-7221;Reactome: R-HSA-5673001 "Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"NrCAM interactions";"Synaptic adhesion-like molecules";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade" XP_030032686.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037298911.1 3 Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33 "Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis" XP_037298916.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_037297560.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030030614.2 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" XP_030029121.1 3 Reactome: R-HSA-111471;Reactome: R-HSA-140837;Reactome: R-HSA-9645722 "Apoptotic factor-mediated response";"Intrinsic Pathway of Fibrin Clot Formation";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function" XP_037303283.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037295566.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037294237.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037302218.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_030040981.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_037302491.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_030023376.2 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_030039461.2 3 Reactome: R-HSA-3299685;KEGG: 00240+3.6.1.17;KEGG: 00230+3.6.1.17 "Detoxification of Reactive Oxygen Species";"Pyrimidine metabolism";"Purine metabolism" XP_030028993.1 8 MetaCyc: PWY-7198;Reactome: R-HSA-499943;MetaCyc: PWY-7184;KEGG: 00240+2.7.4.9;MetaCyc: PWY-6545;MetaCyc: PWY-7197;MetaCyc: PWY-7187;MetaCyc: PWY-7210 "Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" XP_030019716.1 10 MetaCyc: PWY-5826;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4041;MetaCyc: PWY-7112 "Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification" XP_030035588.2 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" XP_037297929.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037300433.1 5 Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-1257604 "VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"PIP3 activates AKT signaling" XP_037298814.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_037303068.1 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_037299802.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_030022202.2 16 Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9633012 "Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_037295913.1 3 Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-381038 "Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"XBP1(S) activates chaperone genes" XP_037303025.1 5 Reactome: R-HSA-6784531;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-77595 "tRNA processing in the nucleus";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs" XP_030028110.2 15 MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-7383;MetaCyc: PWY-6142;KEGG: 00010+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-2221;MetaCyc: PWY-7003;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-5723;MetaCyc: PWY-6886;MetaCyc: PWY-7218;KEGG: 00230+2.7.1.40 "Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Entner-Doudoroff pathway I";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycerol degradation to butanol";"Glycolysis";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"1-butanol autotrophic biosynthesis (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Purine metabolism" XP_030032839.2 3 MetaCyc: PWY-5963;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.9 "Thio-molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_037293943.1 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" XP_037295007.1 13 Reactome: R-HSA-2024101;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52 "CS/DS degradation";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series" XP_037297533.1 6 MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism" XP_037301756.1 10 Reactome: R-HSA-70370;Reactome: R-HSA-5609977;KEGG: 00052+5.1.3.2;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7328;MetaCyc: PWY-6397;MetaCyc: PWY-3821;MetaCyc: PWY-6527;MetaCyc: PWY-6317;MetaCyc: PWY-7344 "Galactose catabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose detoxification";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"UDP-alpha-D-galactose biosynthesis" XP_030033047.1 10 Reactome: R-HSA-163680;Reactome: R-HSA-380972;Reactome: R-HSA-1445148;Reactome: R-HSA-1632852;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;Reactome: R-HSA-5628897;Reactome: R-HSA-9613354;Reactome: R-HSA-200425;Reactome: R-HSA-2151209 "AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Macroautophagy";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"TP53 Regulates Metabolic Genes";"Lipophagy";"Carnitine metabolism";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation" XP_037292656.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037297866.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_030040693.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_037299390.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_030020642.1 11 MetaCyc: PWY-5695;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6607;MetaCyc: PWY-6608;MetaCyc: PWY-6999;MetaCyc: PWY-6596;MetaCyc: PWY-6606;Reactome: R-HSA-74259;MetaCyc: PWY-6538;MetaCyc: PWY-5497;Reactome: R-HSA-8851680 "Inosine 5'-phosphate degradation";"Purine metabolism";"Guanosine nucleotides degradation I";"Guanosine nucleotides degradation III";"Theophylline degradation";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation II";"Purine catabolism";"Caffeine degradation III (bacteria, via demethylation)";"Purine nucleobases degradation II (anaerobic)";"Butyrophilin (BTN) family interactions" XP_030032636.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_030028776.1 15 MetaCyc: PWY-6886;MetaCyc: PWY-5723;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7218;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-7003;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-2221;KEGG: 00620+2.7.1.40;MetaCyc: PWY-8004 "1-butanol autotrophic biosynthesis (engineered)";"Rubisco shunt";"Purine metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pyruvate metabolism";"Entner-Doudoroff pathway I" XP_037297774.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-75953 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation" XP_030031947.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037297191.1 1 Reactome: R-HSA-72731 "Recycling of eIF2:GDP" XP_037294006.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037296149.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037301160.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030020024.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_037303231.1 42 Reactome: R-HSA-5693571;Reactome: R-HSA-606279;Reactome: R-HSA-73772;Reactome: R-HSA-69473;Reactome: R-HSA-1912408;Reactome: R-HSA-9609690;Reactome: R-HSA-427389;Reactome: R-HSA-427413;Reactome: R-HSA-8936459;Reactome: R-HSA-5578749;Reactome: R-HSA-2559582;Reactome: R-HSA-9610379;Reactome: R-HSA-5334118;Reactome: R-HSA-3214858;Reactome: R-HSA-912446;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-9018519;Reactome: R-HSA-5250924;Reactome: R-HSA-8939236;Reactome: R-HSA-73728;Reactome: R-HSA-2299718;Reactome: R-HSA-9616222;Reactome: R-HSA-212300;Reactome: R-HSA-5693565;Reactome: R-HSA-110331;Reactome: R-HSA-110329;Reactome: R-HSA-3214842;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-3214841;Reactome: R-HSA-3214815;Reactome: R-HSA-1221632;Reactome: R-HSA-5617472;Reactome: R-HSA-977225;Reactome: R-HSA-2559580;Reactome: R-HSA-171306;Reactome: R-HSA-110330;Reactome: R-HSA-4551638;Reactome: R-HSA-3214847;Reactome: R-HSA-110328 "Nonhomologous End-Joining (NHEJ)";"Deposition of new CENPA-containing nucleosomes at the centromere";"RNA Polymerase I Promoter Escape";"G2/M DNA damage checkpoint";"Pre-NOTCH Transcription and Translation";"HCMV Early Events";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional regulation by small RNAs";"Senescence-Associated Secretory Phenotype (SASP)";"HCMV Late Events";"DNA methylation";"RMTs methylate histone arginines";"Meiotic recombination";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"Estrogen-dependent gene expression";"B-WICH complex positively regulates rRNA expression";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase I Promoter Opening";"Condensation of Prophase Chromosomes";"Transcriptional regulation of granulopoiesis";"PRC2 methylates histones and DNA";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cleavage of the damaged purine";"Cleavage of the damaged pyrimidine";"HDMs demethylate histones";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"PKMTs methylate histone lysines";"HDACs deacetylate histones";"Meiotic synapsis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Amyloid fiber formation";"Oxidative Stress Induced Senescence";"Packaging Of Telomere Ends";"Recognition and association of DNA glycosylase with site containing an affected purine";"SUMOylation of chromatin organization proteins";"HATs acetylate histones";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" XP_030035775.1 16 Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-1234176;Reactome: R-HSA-167238;Reactome: R-HSA-180585;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-9010553;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-75955 "Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Pausing and recovery of Tat-mediated HIV elongation";"Vif-mediated degradation of APOBEC3G";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of expression of SLITs and ROBOs";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"RNA Polymerase II Transcription Elongation" XP_037298727.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_030033578.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807 "Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism" XP_037302950.1 2 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis" XP_030032294.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-191859 "RNA polymerase II transcribes snRNA genes";"snRNP Assembly" XP_037302594.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_030033054.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037301124.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_030028145.2 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_037301436.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_037302437.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037298755.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_030023256.1 7 Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-1655829;Reactome: R-HSA-168333;Reactome: R-HSA-203927;Reactome: R-HSA-165054;Reactome: R-HSA-5578749 "Nuclear import of Rev protein";"tRNA processing in the nucleus";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"NEP/NS2 Interacts with the Cellular Export Machinery";"MicroRNA (miRNA) biogenesis";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs" XP_030031562.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_030028369.1 4 Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219 "Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_030023821.2 6 MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7433 "Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation" XP_030038227.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_037297056.1 6 KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817 "Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_030026352.2 16 Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-192823 "Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation" XP_030026511.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_030038613.1 5 Reactome: R-HSA-168164;Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-937041 "Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1" XP_030032029.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_030033097.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_030027752.2 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_037295346.1 7 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection" XP_030022730.2 20 Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-176187;Reactome: R-HSA-6782210;Reactome: R-HSA-69091;Reactome: R-HSA-110314 "Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex" XP_030040226.1 3 KEGG: 00510+2.4.1.267;Reactome: R-HSA-4724289;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Defective ALG6 causes ALG6-CDG (CDG-1c)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_030035729.2 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_030029401.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_030041218.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_037303443.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_030029497.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_030027561.2 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_030020903.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_030031956.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_030033451.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_037300788.1 7 Reactome: R-HSA-6798695;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-373753;Reactome: R-HSA-264870;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001 "Neutrophil degranulation";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"Nephrin family interactions";"Caspase-mediated cleavage of cytoskeletal proteins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade" XP_037300013.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037295613.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_030037906.1 5 Reactome: R-HSA-69473;Reactome: R-HSA-5689901;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571 "G2/M DNA damage checkpoint";"Metalloprotease DUBs";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)" XP_030038446.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1" XP_037301782.1 6 Reactome: R-HSA-201722;Reactome: R-HSA-8866654;Reactome: R-HSA-5632684;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of the beta-catenin:TCF transactivating complex";"E3 ubiquitin ligases ubiquitinate target proteins";"Hedgehog 'on' state";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_030020705.1 7 Reactome: R-HSA-1660499;KEGG: 00562+2.7.1.67;MetaCyc: PWY-6352;MetaCyc: PWY-6351;KEGG: 04070+2.7.1.67;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514 "Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane" XP_030023494.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_037293096.1 7 Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00471+3.5.1.2 "TP53 Regulates Metabolic Genes";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"D-Glutamine and D-glutamate metabolism" XP_037297773.1 4 Reactome: R-HSA-2129379;Reactome: R-HSA-3000178;Reactome: R-HSA-216083;Reactome: R-HSA-3000170 "Molecules associated with elastic fibres";"ECM proteoglycans";"Integrin cell surface interactions";"Syndecan interactions" XP_037301006.1 5 MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-6902 "Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)" XP_030027294.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_037300139.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_030038562.2 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_030024287.2 4 Reactome: R-HSA-6782315;MetaCyc: PWY-7285;MetaCyc: PWY-7286;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)" XP_030024699.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_037292308.1 30 Reactome: R-HSA-2564830;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-167160;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-73776;Reactome: R-HSA-5696400;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73772;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-6781827;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-5696395;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-113418 "Cytosolic iron-sulfur cluster assembly";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Promoter Escape";"Dual Incision in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase I Promoter Escape";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex" XP_030035164.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_030036547.2 5 Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5610787;Reactome: R-HSA-5610783 "Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Hedgehog 'off' state";"Degradation of GLI2 by the proteasome" XP_030022190.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037296934.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_030022842.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_030020367.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_030032000.1 5 Reactome: R-HSA-171007;Reactome: R-HSA-376172;KEGG: 04150+2.7.11.24;Reactome: R-HSA-4420097;Reactome: R-HSA-168638 "p38MAPK events";"DSCAM interactions";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"NOD1/2 Signaling Pathway" XP_030035935.1 40 Reactome: R-HSA-77075;Reactome: R-HSA-72203;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-5578749;Reactome: R-HSA-5601884;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-6782210;Reactome: R-HSA-167162;Reactome: R-HSA-72163;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-167243;Reactome: R-HSA-9018519;Reactome: R-HSA-167161;Reactome: R-HSA-167287;Reactome: R-HSA-75953;Reactome: R-HSA-72165;Reactome: R-HSA-76042;Reactome: R-HSA-6781823;Reactome: R-HSA-167242;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-203927;Reactome: R-HSA-6796648;Reactome: R-HSA-6803529;Reactome: R-HSA-5617472;Reactome: R-HSA-75955;Reactome: R-HSA-168325;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-73776 "RNA Pol II CTD phosphorylation and interaction with CE";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcriptional regulation by small RNAs";"PIWI-interacting RNA (piRNA) biogenesis";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II HIV Promoter Escape";"mRNA Splicing - Major Pathway";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"HIV Transcription Initiation";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of TC-NER Pre-Incision Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"FGFR2 alternative splicing";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Transcription Elongation";"Viral Messenger RNA Synthesis";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape" XP_037294308.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_030023069.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_030026829.2 14 Reactome: R-HSA-1483191;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8053;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052;Reactome: R-HSA-4419969;KEGG: 00565+3.1.3.4;Reactome: R-HSA-1483213;MetaCyc: PWY-6453;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;Reactome: R-HSA-75109 "Synthesis of PC";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Depolymerisation of the Nuclear Lamina";"Ether lipid metabolism";"Synthesis of PE";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Triglyceride biosynthesis" XP_030040155.2 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037297343.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_030022330.2 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_030021924.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_037301212.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037294734.1 13 Reactome: R-HSA-114508;Reactome: R-HSA-4086398;Reactome: R-HSA-381676;Reactome: R-HSA-112043;Reactome: R-HSA-139853;Reactome: R-HSA-2029485;Reactome: R-HSA-5607763;Reactome: R-HSA-5578775;Reactome: R-HSA-2871809;Reactome: R-HSA-1489509;Reactome: R-HSA-5218921;Reactome: R-HSA-983695;Reactome: R-HSA-422356 "Effects of PIP2 hydrolysis";"Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PLC beta mediated events";"Elevation of cytosolic Ca2+ levels";"Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation";"Ion homeostasis";"FCERI mediated Ca+2 mobilization";"DAG and IP3 signaling";"VEGFR2 mediated cell proliferation";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Regulation of insulin secretion" XP_037294647.1 17 MetaCyc: PWY-7179-1;Reactome: R-HSA-6798695;MetaCyc: PWY-6609;Reactome: R-HSA-74259;Reactome: R-HSA-74217;MetaCyc: PWY-6611;MetaCyc: PWY-6620;KEGG: 00230+2.4.2.1;KEGG: 00760+2.4.2.1;KEGG: 00240+2.4.2.1;MetaCyc: PWY-4202;MetaCyc: PWY-7179;MetaCyc: PWY-6644;MetaCyc: PWY-5532;MetaCyc: PWY-6608;MetaCyc: PWY-5695;MetaCyc: PWY-6627 "Purine deoxyribonucleosides degradation II";"Neutrophil degranulation";"Adenine and adenosine salvage III";"Purine catabolism";"Purine salvage";"Adenine and adenosine salvage V";"Guanine and guanosine salvage";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Pyrimidine metabolism";"Arsenate detoxification I (mammalian)";"Purine deoxyribonucleosides degradation I";"Fluoroacetate and fluorothreonine biosynthesis";"Nucleoside and nucleotide degradation (archaea)";"Guanosine nucleotides degradation III";"Inosine 5'-phosphate degradation";"Salinosporamide A biosynthesis" XP_030025410.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030033094.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_037297163.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_030020088.2 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_030034351.2 6 Reactome: R-HSA-73817;MetaCyc: PWY-7234;MetaCyc: PWY-6124;KEGG: 00230+6.3.2.6;KEGG: 00230+4.1.1.21;MetaCyc: PWY-6123 "Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I" XP_030024165.1 2 Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Cargo concentration in the ER";"COPII-mediated vesicle transport" XP_030031362.1 10 MetaCyc: PWY-6537;Reactome: R-HSA-916853;MetaCyc: PWY-4321;KEGG: 00640+2.6.1.19;KEGG: 00650+2.6.1.19;KEGG: 00410+2.6.1.19;MetaCyc: PWY-6535;MetaCyc: PWY-6536;MetaCyc: PWY-5022;KEGG: 00250+2.6.1.19 "4-aminobutanoate degradation II";"Degradation of GABA";"L-glutamate degradation IV";"Propanoate metabolism";"Butanoate metabolism";"beta-Alanine metabolism";"4-aminobutanoate degradation I";"4-aminobutanoate degradation III";"4-aminobutanoate degradation V";"Alanine, aspartate and glutamate metabolism" XP_030031298.2 3 KEGG: 00051+1.1.1.271;KEGG: 00520+1.1.1.271;Reactome: R-HSA-6787639 "Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis" XP_030029149.2 2 Reactome: R-HSA-1799339;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation" XP_030026303.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_030024406.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_037295282.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_037295866.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_030033583.2 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_030033557.1 16 Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-174048;Reactome: R-HSA-141430;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-176407 "Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase" XP_037295391.1 3 Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807 "Neutrophil degranulation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)" XP_030023535.2 5 KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661 "Lysine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation" XP_030021952.1 31 MetaCyc: PWY-5142;MetaCyc: PWY-5989;Reactome: R-HSA-75105;MetaCyc: PWY-5973;MetaCyc: PWY-7858;MetaCyc: PWYG-321;Reactome: R-HSA-2426168;MetaCyc: PWY-5366;MetaCyc: PWY-7663;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-199220;MetaCyc: PWY-5147;MetaCyc: PWY-5994;MetaCyc: PWY-5971;MetaCyc: PWY-7388;MetaCyc: PWY-8049;MetaCyc: PWY-7723;Reactome: R-HSA-9029558;MetaCyc: PWY-6282;MetaCyc: PWY-5367;MetaCyc: PWY-7664;MetaCyc: PWY-6799;MetaCyc: PWY-6519;MetaCyc: PWY-4381;Reactome: R-HSA-163765;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8012;MetaCyc: PWY-8047;MetaCyc: PWY-7746;MetaCyc: PWY-5966-1;MetaCyc: PWY-6113 "Acyl-[acyl-carrier protein] thioesterase pathway";"Stearate biosynthesis II (bacteria and plants)";"Fatty acyl-CoA biosynthesis";"Cis-vaccenate biosynthesis";"(5Z)-dodecenoate biosynthesis II";"";"Activation of gene expression by SREBF (SREBP)";"Palmitoleate biosynthesis II (plants and bacteria)";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Oleate biosynthesis I (plants)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Pederin biosynthesis";"Bacterial bioluminescence";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Petroselinate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (plant mitochondria)";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (bacteria and plants)";"ChREBP activates metabolic gene expression";"Biotin metabolism";"Mupirocin biosynthesis";"Bryostatin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Superpathway of mycolate biosynthesis" XP_037294780.1 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" XP_037299891.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037301679.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_030020628.1 14 MetaCyc: PWY-5695;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6607;KEGG: 00230+1.17.1.4+1.17.3.2;MetaCyc: PWY-6608;MetaCyc: PWY-6999;MetaCyc: PWY-6596;KEGG: 00232+1.17.3.2;KEGG: 00983+1.17.3.2;Reactome: R-HSA-74259;MetaCyc: PWY-6606;MetaCyc: PWY-6538;MetaCyc: PWY-5497;Reactome: R-HSA-8851680 "Inosine 5'-phosphate degradation";"Purine metabolism";"Guanosine nucleotides degradation I";"Purine metabolism";"Guanosine nucleotides degradation III";"Theophylline degradation";"Adenosine nucleotides degradation I";"Caffeine metabolism";"Drug metabolism - other enzymes";"Purine catabolism";"Guanosine nucleotides degradation II";"Caffeine degradation III (bacteria, via demethylation)";"Purine nucleobases degradation II (anaerobic)";"Butyrophilin (BTN) family interactions" XP_037297289.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_037294001.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_030022310.2 4 MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14 "Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism" XP_037298450.1 6 Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-390471 "Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis" XP_037296461.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037302780.1 1 MetaCyc: PWY-6938 "NADH repair" XP_030037161.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030022229.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_030031876.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_030029366.1 11 Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5358565;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5358606 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)" XP_037298891.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_030024757.1 2 Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3 "Platelet degranulation";"Aminoacyl-tRNA biosynthesis" XP_037303198.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030027155.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_030040593.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030033986.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037298078.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" YP_001650761.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037294869.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030024223.2 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_030031099.1 10 MetaCyc: PWY-7003;KEGG: 00010+2.7.2.3;MetaCyc: PWY-8004;MetaCyc: PWY-5484;MetaCyc: PWY-6901;KEGG: 00710+2.7.2.3;MetaCyc: PWY-6886;MetaCyc: PWY-1042;Reactome: R-HSA-70171;Reactome: R-HSA-70263 "Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis";"Gluconeogenesis" XP_030026581.2 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_037299983.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_030035759.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_037300046.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037297110.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_030021978.2 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037300729.1 17 KEGG: 00620+6.4.1.2;Reactome: R-HSA-200425;MetaCyc: PWY-5743;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5789;Reactome: R-HSA-2426168;Reactome: R-HSA-3371599;KEGG: 00061+6.4.1.2;MetaCyc: PWY-6679;MetaCyc: PWY-6722;MetaCyc: PWY-5966-1;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5744;Reactome: R-HSA-196780;KEGG: 00640+6.4.1.2;Reactome: R-HSA-163765;MetaCyc: PWY-4381 "Pyruvate metabolism";"Carnitine metabolism";"3-hydroxypropanoate cycle";"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Activation of gene expression by SREBF (SREBP)";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis";"Jadomycin biosynthesis";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Aflatoxin biosynthesis";"Glyoxylate assimilation";"Biotin transport and metabolism";"Propanoate metabolism";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (bacteria and plants)" XP_037296322.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_030040482.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_037300563.1 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" XP_030037256.2 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037300732.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030026841.2 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_030024963.1 16 Reactome: R-HSA-426496;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-9029569;Reactome: R-HSA-2559580;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-8936459;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408 "Post-transcriptional silencing by small RNAs";"Ca2+ pathway";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oxidative Stress Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation" XP_030023712.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037303014.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037294651.1 4 Reactome: R-HSA-156581;Reactome: R-HSA-6790901;Reactome: R-HSA-6782315;Reactome: R-HSA-72764 "Methylation";"rRNA modification in the nucleus and cytosol";"tRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination" XP_030021478.1 5 Reactome: R-HSA-8876198;Reactome: R-HSA-1445148;Reactome: R-HSA-1660499;Reactome: R-HSA-6798695;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Synthesis of PIPs at the plasma membrane";"Neutrophil degranulation";"RAB geranylgeranylation" XP_037297188.1 26 Reactome: R-HSA-933541;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472;Reactome: R-HSA-9614657;Reactome: R-HSA-3134973;Reactome: R-HSA-918233;Reactome: R-HSA-400253;Reactome: R-HSA-3214847;Reactome: R-HSA-9018519;Reactome: R-HSA-9013695;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-3371568;Reactome: R-HSA-9617629;Reactome: R-HSA-2644606;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-1912408;Reactome: R-HSA-5621575;Reactome: R-HSA-3899300;Reactome: R-HSA-2894862;Reactome: R-HSA-8866907;Reactome: R-HSA-210744;Reactome: R-HSA-201722 "TRAF6 mediated IRF7 activation";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"FOXO-mediated transcription of cell death genes";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"TRAF3-dependent IRF activation pathway";"Circadian Clock";"HATs acetylate histones";"Estrogen-dependent gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Attenuation phase";"Regulation of FOXO transcriptional activity by acetylation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Pre-NOTCH Transcription and Translation";"CD209 (DC-SIGN) signaling";"SUMOylation of transcription cofactors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Formation of the beta-catenin:TCF transactivating complex" XP_030025984.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_030029144.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection" XP_037302612.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes" XP_037300702.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037294794.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_037295097.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_037300612.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037292992.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_037299117.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_030021679.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167162 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape" XP_037300712.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037293316.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_037301882.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-4341670;Reactome: R-HSA-1660662;Reactome: R-HSA-4085001 "Neutrophil degranulation";"MHC class II antigen presentation";"Defective NEU1 causes sialidosis";"Glycosphingolipid metabolism";"Sialic acid metabolism" XP_030037463.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_037293658.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_030031777.1 7 MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-5469 "Matairesinol biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Sesamin biosynthesis" XP_037294091.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030037833.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_037294593.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_037292569.1 6 Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-6804756 "Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation" XP_037298233.1 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_037297393.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037302031.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_030029908.1 15 MetaCyc: PWY-7218;KEGG: 00230+2.7.1.40;MetaCyc: PWY-5723;MetaCyc: PWY-6886;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-8004;KEGG: 00620+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-6142 "Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Purine metabolism";"Rubisco shunt";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Pyruvate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_030026840.2 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_030040307.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_030038484.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_037296137.1 29 Reactome: R-HSA-73772;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-73863;Reactome: R-HSA-5696395;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-6781827;Reactome: R-HSA-76042;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-75955;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-73776;Reactome: R-HSA-167158 "RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Termination";"Formation of Incision Complex in GG-NER";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex" XP_030036420.2 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_030020068.1 5 Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828 "EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"Clathrin-mediated endocytosis" XP_037300143.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037302529.1 4 MetaCyc: PWY-5188;MetaCyc: PWY-5189;Reactome: R-HSA-189451;KEGG: 00860+2.5.1.61 "Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism" XP_037297956.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_030026164.2 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037299940.1 5 MetaCyc: PWY-6692;MetaCyc: PWY-7279;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7082;MetaCyc: PWY-3781 "Fe(II) oxidation";"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration I (cytochrome c)" XP_037302564.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_030024729.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_030038301.1 8 Reactome: R-HSA-6796648;Reactome: R-HSA-450341;Reactome: R-HSA-9633012;Reactome: R-HSA-8943724;Reactome: R-HSA-2151201;Reactome: R-HSA-3214847;Reactome: R-HSA-9018519;Reactome: R-HSA-400253 "TP53 Regulates Transcription of DNA Repair Genes";"Activation of the AP-1 family of transcription factors";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of PTEN gene transcription";"Transcriptional activation of mitochondrial biogenesis";"HATs acetylate histones";"Estrogen-dependent gene expression";"Circadian Clock" XP_030031784.1 10 MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-5826;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7559 "Glutathione-mediated detoxification II";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"Glutathione degradation (DUG pathway" XP_037292278.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037298084.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_030029152.1 7 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway" XP_030024979.2 1 Reactome: R-HSA-8951664 "Neddylation" XP_037300789.1 7 Reactome: R-HSA-6798695;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-264870;Reactome: R-HSA-373753 "Neutrophil degranulation";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Caspase-mediated cleavage of cytoskeletal proteins";"Nephrin family interactions" XP_037293192.1 5 Reactome: R-HSA-164843;Reactome: R-HSA-6798695;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;Reactome: R-HSA-3270619 "2-LTR circle formation";"Neutrophil degranulation";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN" XP_037296571.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_030032518.1 1 Reactome: R-HSA-419771 "Opsins" XP_030032289.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118 "SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors" XP_030027941.1 11 MetaCyc: PWY-6606;KEGG: 00240+3.1.3.5;MetaCyc: PWY-6607;MetaCyc: PWY-7185;MetaCyc: PWY-7821;KEGG: 00760+3.1.3.5;MetaCyc: PWY-5695;MetaCyc: PWY-5381;KEGG: 00230+3.1.3.5;MetaCyc: PWY-6608;MetaCyc: PWY-6596 "Guanosine nucleotides degradation II";"Pyrimidine metabolism";"Guanosine nucleotides degradation I";"UTP and CTP dephosphorylation I";"Tunicamycin biosynthesis";"Nicotinate and nicotinamide metabolism";"Inosine 5'-phosphate degradation";"Pyridine nucleotide cycling (plants)";"Purine metabolism";"Guanosine nucleotides degradation III";"Adenosine nucleotides degradation I" XP_037292860.1 31 KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6799;MetaCyc: PWY-7664;MetaCyc: PWY-4381;MetaCyc: PWY-6519;Reactome: R-HSA-163765;MetaCyc: PWY-6282;MetaCyc: PWY-5367;MetaCyc: PWY-7723;Reactome: R-HSA-9029558;MetaCyc: PWY-8049;MetaCyc: PWY-6113;MetaCyc: PWY-5966-1;MetaCyc: PWY-7746;MetaCyc: PWY-8012;MetaCyc: PWY-8047;Reactome: R-HSA-2426168;MetaCyc: PWYG-321;MetaCyc: PWY-5973;MetaCyc: PWY-5989;Reactome: R-HSA-75105;MetaCyc: PWY-7858;MetaCyc: PWY-5142;MetaCyc: PWY-7388;MetaCyc: PWY-5971;MetaCyc: PWY-5994;MetaCyc: PWY-5147;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-199220;MetaCyc: PWY-7663;MetaCyc: PWY-5366 "Biotin metabolism";"Fatty acid biosynthesis initiation (plant mitochondria)";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"ChREBP activates metabolic gene expression";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Petroselinate biosynthesis";"Bacterial bioluminescence";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Pederin biosynthesis";"Superpathway of mycolate biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Mycobacterial sulfolipid biosynthesis";"Mupirocin biosynthesis";"Bryostatin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"";"Cis-vaccenate biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Fatty acyl-CoA biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Acyl-[acyl-carrier protein] thioesterase pathway";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Gondoate biosynthesis (anaerobic)";"Palmitoleate biosynthesis II (plants and bacteria)" XP_037293495.1 7 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_037301636.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037297361.1 8 MetaCyc: PWY-1861;KEGG: 00030+2.2.1.2;Reactome: R-HSA-8950505;Reactome: R-HSA-6791462;MetaCyc: PWY-5723;Reactome: R-HSA-6791055;Reactome: R-HSA-71336;Reactome: R-HSA-163754 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Rubisco shunt";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Pentose phosphate pathway";"Insulin effects increased synthesis of Xylulose-5-Phosphate" XP_037293264.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_030030091.2 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037299976.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_030035582.1 11 MetaCyc: PWY-6549;MetaCyc: PWY-5913;MetaCyc: PWY-6969;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7254;MetaCyc: PWY-7268;MetaCyc: PWY-7124;KEGG: 00020+1.1.1.42;KEGG: 00720+1.1.1.42;Reactome: R-HSA-71403;MetaCyc: PWY-6728 "L-glutamine biosynthesis III";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glutathione metabolism";"TCA cycle VII (acetate-producers)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Ethylene biosynthesis V (engineered)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle" XP_037298238.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_037300879.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037299377.1 6 Reactome: R-HSA-9022537;Reactome: R-HSA-3214815;Reactome: R-HSA-1989781;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-9609690 "Loss of MECP2 binding ability to the NCoR/SMRT complex";"HDACs deacetylate histones";"PPARA activates gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"HCMV Early Events" XP_030026865.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_037292544.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_037293610.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_037299676.1 2 Reactome: R-HSA-877312;Reactome: R-HSA-6807004 "Regulation of IFNG signaling";"Negative regulation of MET activity" XP_030032675.1 3 KEGG: 00860+1.16.3.1;Reactome: R-HSA-1268020;Reactome: R-HSA-1362409 "Porphyrin and chlorophyll metabolism";"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis" XP_030034336.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037301264.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_030024497.2 9 Reactome: R-HSA-5649702;Reactome: R-HSA-9657050;Reactome: R-HSA-110331;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110330;Reactome: R-HSA-9656256;Reactome: R-HSA-110328;Reactome: R-HSA-9656255 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Defective OGG1 Localization";"Cleavage of the damaged purine";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective OGG1 Substrate Processing";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective OGG1 Substrate Binding" XP_037300815.1 7 MetaCyc: PWY-6122;KEGG: 00250+2.4.2.14;KEGG: 00230+2.4.2.14;Reactome: R-HSA-73817;MetaCyc: PWY-6277;MetaCyc: PWY-7282;MetaCyc: PWY-6121 "5-aminoimidazole ribonucleotide biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I" XP_030040079.1 3 MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695 "Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Neutrophil degranulation" XP_030030974.2 10 MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-7385;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.11;Reactome: R-HSA-70171 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Pentose phosphate pathway";"Galactose metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Glycolysis" XP_037301224.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037300044.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_030040074.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037297583.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_030034996.2 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_037294234.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_030026606.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" XP_030035541.1 9 MetaCyc: PWY-7039;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;Reactome: R-HSA-112043;MetaCyc: PWY-8052;Reactome: R-HSA-416476;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-6351 "Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis" XP_030026708.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030029227.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_030031977.1 10 Reactome: R-HSA-163680;Reactome: R-HSA-380972;Reactome: R-HSA-1445148;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-9613354;Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;Reactome: R-HSA-2151209;Reactome: R-HSA-200425 "AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Lipophagy";"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Carnitine metabolism" XP_030032579.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037293237.1 3 MetaCyc: PWY-6619;Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20 "Adenine and adenosine salvage VI";"Purine salvage";"Purine metabolism" XP_037302604.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_030031324.1 12 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-141444 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Aggrephagy";"RHO GTPases Activate Formins";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_037301503.1 2 Reactome: R-HSA-525793;Reactome: R-HSA-373752 "Myogenesis";"Netrin-1 signaling" XP_030033604.1 57 Reactome: R-HSA-1234176;Reactome: R-HSA-8939236;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-180585;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-187577 "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Vpu mediated degradation of CD4";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Vif-mediated degradation of APOBEC3G";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21" XP_037300098.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_037293232.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037300155.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_030036906.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_030036658.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030020608.2 5 MetaCyc: PWY-7922;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis" XP_030037908.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_030027472.1 3 Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism";"Pentose phosphate pathway" XP_030024964.1 2 Reactome: R-HSA-204626;MetaCyc: PWY-5905 "Hypusine synthesis from eIF5A-lysine";"Hypusine biosynthesis" XP_030033351.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_030022740.2 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" XP_030022394.2 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_030023202.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" XP_030021034.1 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_037302048.1 4 Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085;KEGG: 00564+3.1.1.7 "Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Glycerophospholipid metabolism" XP_037296734.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_037294303.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_037296296.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_030023886.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_037298914.1 3 KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II" XP_037296009.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037293185.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_030031327.1 12 Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-3371497 "Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Aggrephagy";"HCMV Early Events";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_030020271.2 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_037295078.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_037292600.1 12 KEGG: 00680+4.1.2.13;MetaCyc: PWY-1042;Reactome: R-HSA-70263;Reactome: R-HSA-70171;KEGG: 00710+4.1.2.13;MetaCyc: PWY-1861;KEGG: 00030+4.1.2.13;KEGG: 00010+4.1.2.13;KEGG: 00051+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-7385 "Methane metabolism";"Glycolysis IV (plant cytosol)";"Gluconeogenesis";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)" XP_037301024.1 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_037300768.1 6 Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-380994 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_037296160.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037298716.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_030035550.2 3 KEGG: 00860+1.3.3.3;Reactome: R-HSA-189451;MetaCyc: PWY-7159 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)" XP_037302586.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-6798695 "SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation" XP_037293094.1 1 Reactome: R-HSA-2173788 "Downregulation of TGF-beta receptor signaling" XP_030034051.2 4 Reactome: R-HSA-446193;Reactome: R-HSA-4720489;KEGG: 00513+2.4.1.260;KEGG: 00510+2.4.1.260 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis" XP_030041356.2 8 Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-6798695;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-2565942 "AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Neutrophil degranulation";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition" XP_030020649.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037292232.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_030035779.2 6 Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867 "Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex" XP_030035259.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_030027073.2 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_037300556.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_037299476.1 5 Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084 "Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_037298448.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037299412.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_030037735.2 1 Reactome: R-HSA-8949613 "Cristae formation" XP_030022892.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_030031121.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_037302154.1 3 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-420029 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions" XP_030024376.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037301162.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030025401.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030027496.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_037300570.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_030027614.1 3 MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3 "Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism" XP_037303158.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_030021969.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_030036654.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030020956.2 4 Reactome: R-HSA-1474228;Reactome: R-HSA-2243919;Reactome: R-HSA-2214320;Reactome: R-HSA-1650814 "Degradation of the extracellular matrix";"Crosslinking of collagen fibrils";"Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes" XP_037299043.1 7 Reactome: R-HSA-416476;Reactome: R-HSA-114608;Reactome: R-HSA-418594;Reactome: R-HSA-381426;Reactome: R-HSA-140837;Reactome: R-HSA-375276;Reactome: R-HSA-8957275 "G alpha (q) signalling events";"Platelet degranulation";"G alpha (i) signalling events";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Intrinsic Pathway of Fibrin Clot Formation";"Peptide ligand-binding receptors";"Post-translational protein phosphorylation" XP_037295208.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" YP_001650752.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_030020908.1 18 MetaCyc: PWY-6728;KEGG: 00680+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-7115;MetaCyc: PWY-561;MetaCyc: PWY-8086;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00270+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-5913;MetaCyc: PWY-1622;KEGG: 00020+1.1.1.37;MetaCyc: PWY-5392;KEGG: 00720+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-6969 "Methylaspartate cycle";"Methane metabolism";"Gluconeogenesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Superpathway of glyoxylate cycle and fatty acid degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation in photosynthetic organisms";"Anaerobic energy metabolism (invertebrates, cytosol)";"Cysteine and methionine metabolism";"Pyruvate metabolism";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"Formaldehyde assimilation I (serine pathway)";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" XP_030027820.2 14 MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7587;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-6453;MetaCyc: PWY-5981;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-7782;Reactome: R-HSA-1483166 "Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Synthesis of PA" XP_030040460.1 18 KEGG: 00591+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-8053;MetaCyc: PWY-8051;Reactome: R-HSA-1482922;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;MetaCyc: PWY-7417;MetaCyc: PWY-6803 "Linoleic acid metabolism";"Synthesis of PA";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Acyl chain remodelling of PS";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Acyl chain remodelling of PI";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Acyl chain remodelling of PG";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing" XP_030021049.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557 "Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis" XP_030021759.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030026577.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_030021809.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030030340.1 5 Reactome: R-HSA-6811434;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-204005 "COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic";"COPII-mediated vesicle transport" XP_030023510.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_037294164.1 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" XP_037293049.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_030035292.1 17 Reactome: R-HSA-5358565;Reactome: R-HSA-6782210;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-69166;Reactome: R-HSA-5696397;Reactome: R-HSA-5358606;Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-69183;Reactome: R-HSA-5696400;Reactome: R-HSA-174414;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-174417 "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"Processive synthesis on the lagging strand";"Dual Incision in GG-NER";"Processive synthesis on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand (Lagging Strand) Synthesis" XP_037293419.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_030037310.2 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_030036120.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_030034673.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_037295907.1 8 KEGG: 00900+1.1.1.34;MetaCyc: PWY-7391;MetaCyc: PWY-7524;Reactome: R-HSA-2426168;MetaCyc: PWY-922;MetaCyc: PWY-6174;Reactome: R-HSA-1989781;Reactome: R-HSA-191273 "Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"PPARA activates gene expression";"Cholesterol biosynthesis" XP_037297655.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037294045.1 9 Reactome: R-HSA-8951664;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696394;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823 "Neddylation";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER";"DNA Damage Recognition in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex" XP_037293913.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_030027729.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_030029226.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037300528.1 3 Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-1268020 "Respiratory electron transport";"Complex I biogenesis";"Mitochondrial protein import" XP_037297994.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_030023576.2 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_030037013.1 24 Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399 "Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"MHC class II antigen presentation";"HCMV Early Events";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"Recycling pathway of L1";"Mitotic Prometaphase";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy" XP_030022208.2 7 MetaCyc: PWY-6363;MetaCyc: PWY-4702;KEGG: 04070+3.1.3.25;KEGG: 00521+3.1.3.25;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;MetaCyc: PWY-2301 "D-myo-inositol (1,4,5)-trisphosphate degradation";"Phytate degradation I";"Phosphatidylinositol signaling system";"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Myo-inositol biosynthesis" XP_037299990.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_030032651.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037301293.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" XP_030037678.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_030041339.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_037299007.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_030039296.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030026785.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037292191.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_030033907.2 8 KEGG: 04658+3.1.3.16;MetaCyc: PWY-7817;KEGG: 05235+3.1.3.16;KEGG: 00564+3.1.3.27;MetaCyc: PWY-5269;MetaCyc: PWY-5668;Reactome: R-HSA-1483148;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"Type I lipoteichoic acid biosynthesis (S. aureus)";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis II";"Cardiolipin biosynthesis I";"Synthesis of PG";"T cell receptor signaling pathway" XP_037299006.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_030028598.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037296033.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_030033558.1 16 Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-176407;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-174048;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-2467813;Reactome: R-HSA-8853884;Reactome: R-HSA-983168 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation" XP_030029158.2 4 Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664 "Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation" XP_037296716.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037292369.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030028415.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037295735.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_030033929.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037294707.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037297964.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012 "SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_030020127.2 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037300296.1 14 Reactome: R-HSA-977225;Reactome: R-HSA-9017802;Reactome: R-HSA-2979096;Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-3928665;Reactome: R-HSA-9013700;Reactome: R-HSA-2122948;Reactome: R-HSA-6798695;Reactome: R-HSA-2894862;Reactome: R-HSA-1251985;Reactome: R-HSA-9013507;Reactome: R-HSA-1474228;Reactome: R-HSA-205043 "Amyloid fiber formation";"Noncanonical activation of NOTCH3";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Neutrophil degranulation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Degradation of the extracellular matrix";"NRIF signals cell death from the nucleus" XP_030020280.2 3 Reactome: R-HSA-8878166;Reactome: R-HSA-8939902;Reactome: R-HSA-6785807 "Transcriptional regulation by RUNX2";"Regulation of RUNX2 expression and activity";"Interleukin-4 and Interleukin-13 signaling" XP_037298379.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037295783.1 6 Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-3769402 "Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex" XP_030040227.2 6 MetaCyc: PWY-922;Reactome: R-HSA-2426168;Reactome: R-HSA-191273;KEGG: 00900+2.7.1.36;MetaCyc: PWY-7391;MetaCyc: PWY-6174 "Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)" XP_037293674.1 7 Reactome: R-HSA-1632852;Reactome: R-HSA-8854214;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-5674400;Reactome: R-HSA-165181;Reactome: R-HSA-198323 "Macroautophagy";"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Constitutive Signaling by AKT1 E17K in Cancer";"Inhibition of TSC complex formation by PKB";"AKT phosphorylates targets in the cytosol" XP_030021917.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_030021844.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_037300944.1 5 Reactome: R-HSA-189451;KEGG: 00860+4.2.1.24;MetaCyc: PWY-5189;MetaCyc: PWY-5188;Reactome: R-HSA-6798695 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Neutrophil degranulation" XP_030025264.1 5 Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981;MetaCyc: PWY-6344;MetaCyc: PWY-3341 "Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)" XP_030038600.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_030035730.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_037301464.1 6 Reactome: R-HSA-5083632;Reactome: R-HSA-913709;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290;MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122 "Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis" XP_037298052.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030024867.2 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037295778.1 6 Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex" XP_037297784.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_030019836.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037292292.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_030021522.1 3 MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3 "Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism" XP_037295498.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_037292245.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_030037509.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_030025753.2 5 Reactome: R-HSA-6798695;Reactome: R-HSA-3134975;Reactome: R-HSA-3249367;Reactome: R-HSA-1834941;Reactome: R-HSA-3270619 "Neutrophil degranulation";"Regulation of innate immune responses to cytosolic DNA";"STAT6-mediated induction of chemokines";"STING mediated induction of host immune responses";"IRF3-mediated induction of type I IFN" XP_037303572.1 12 Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-8941856;Reactome: R-HSA-3214847;Reactome: R-HSA-5250924;Reactome: R-HSA-9013695;Reactome: R-HSA-2122947;Reactome: R-HSA-73762;Reactome: R-HSA-2894862;Reactome: R-HSA-210744 "Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"HATs acetylate histones";"B-WICH complex positively regulates rRNA expression";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"RNA Polymerase I Transcription Initiation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells" XP_037302479.1 5 Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_037298909.1 3 KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II" XP_030035153.2 8 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_030038903.2 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_030026560.2 4 Reactome: R-HSA-4719360;Reactome: R-HSA-4717374;Reactome: R-HSA-4719377;Reactome: R-HSA-162699 "Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Synthesis of dolichyl-phosphate mannose" XP_037298400.1 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_030032385.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037298761.1 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" XP_030024709.2 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_037299380.1 2 KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_030023797.1 2 Reactome: R-HSA-500753;Reactome: R-HSA-73621 "Pyrimidine biosynthesis";"Pyrimidine catabolism" XP_030025945.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_030038627.1 5 Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-936964 "Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon" XP_037301826.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_030020481.1 6 KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6;Reactome: R-HSA-6798695;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;Reactome: R-HSA-9033241 "Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism";"Neutrophil degranulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Peroxisomal protein import" XP_037298349.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_030023074.2 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_030025113.2 16 Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-8853884;Reactome: R-HSA-174048;Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-174178 "Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_030025319.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_037299880.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815 "Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones" XP_037294415.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037292931.1 5 Reactome: R-HSA-450321;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors" XP_030040309.1 13 Reactome: R-HSA-2871809;Reactome: R-HSA-2871796;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;Reactome: R-HSA-2029485;Reactome: R-HSA-9027277;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-2424491;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-202433 "FCERI mediated Ca+2 mobilization";"FCERI mediated MAPK activation";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"Role of phospholipids in phagocytosis";"Erythropoietin activates Phospholipase C gamma (PLCG)";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"DAP12 signaling";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Generation of second messenger molecules" XP_037301617.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72689 "Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits" XP_037297112.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_037300420.1 6 Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_030032469.1 8 MetaCyc: PWY-1861;Reactome: R-HSA-6791462;KEGG: 00030+2.2.1.2;Reactome: R-HSA-8950505;MetaCyc: PWY-5723;Reactome: R-HSA-163754;Reactome: R-HSA-6791055;Reactome: R-HSA-71336 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Pentose phosphate pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Rubisco shunt";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Pentose phosphate pathway" XP_030022794.1 3 Reactome: R-HSA-2022854;Reactome: R-HSA-5083627;Reactome: R-HSA-5173105 "Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation" XP_030035278.1 7 MetaCyc: PWY-5484;KEGG: 00010+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00030+3.1.3.11;KEGG: 00051+3.1.3.11;KEGG: 00680+3.1.3.11;KEGG: 00710+3.1.3.11 "Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Methane metabolism";"Carbon fixation in photosynthetic organisms" XP_030031454.1 2 Reactome: R-HSA-8983711;Reactome: R-HSA-909733 "OAS antiviral response";"Interferon alpha/beta signaling" XP_030034836.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_030020557.2 5 Reactome: R-HSA-1679131;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090 "Trafficking and processing of endosomal TLR";"Neutrophil degranulation";"MHC class II antigen presentation";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures" XP_037295503.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_030030517.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030020907.1 18 KEGG: 00270+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-5913;MetaCyc: PWY-561;MetaCyc: PWY-8086;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-7115;KEGG: 00680+1.1.1.37;MetaCyc: PWY-6728;Reactome: R-HSA-70263;MetaCyc: PWY-6969;MetaCyc: PWY-5392;KEGG: 00720+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00020+1.1.1.37 "Cysteine and methionine metabolism";"Pyruvate metabolism";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"Superpathway of glyoxylate cycle and fatty acid degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation in photosynthetic organisms";"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Methane metabolism";"Methylaspartate cycle";"Gluconeogenesis";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Formaldehyde assimilation I (serine pathway)";"Citrate cycle (TCA cycle)" XP_030021971.1 3 KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581;MetaCyc: PWY-6823 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_037293749.1 2 Reactome: R-HSA-2142700;Reactome: R-HSA-2142691 "Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_030022144.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_037302265.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_030023577.2 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_030021802.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030038580.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_030025119.2 3 Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_037292527.1 1 Reactome: R-HSA-110357 "Displacement of DNA glycosylase by APEX1" XP_030027295.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_030029866.1 2 MetaCyc: PWY-6502;Reactome: R-HSA-2393930 "8-oxo-(d)GTP detoxification I";"Phosphate bond hydrolysis by NUDT proteins" XP_037303124.1 11 Reactome: R-HSA-428890;Reactome: R-HSA-5693565;Reactome: R-HSA-2029482;Reactome: R-HSA-525793;Reactome: R-HSA-5685938;Reactome: R-HSA-69231;Reactome: R-HSA-5663213;KEGG: 04660+2.7.10.2;Reactome: R-HSA-983231;Reactome: R-HSA-8940973;Reactome: R-HSA-8939236 "Role of ABL in ROBO-SLIT signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of actin dynamics for phagocytic cup formation";"Myogenesis";"HDR through Single Strand Annealing (SSA)";"Cyclin D associated events in G1";"RHO GTPases Activate WASPs and WAVEs";"T cell receptor signaling pathway";"Factors involved in megakaryocyte development and platelet production";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_030022841.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-6798695 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation" XP_030029379.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_030022133.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_030033066.2 58 KEGG: 00362+4.2.1.17+1.1.1.35;Reactome: R-HSA-1482798;KEGG: 00281+4.2.1.17;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7654;MetaCyc: PWY-6944;KEGG: 00071+4.2.1.17+1.1.1.211;MetaCyc: PWY-5109;KEGG: 00360+4.2.1.17;Reactome: R-HSA-77350;MetaCyc: PWY-5138;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;MetaCyc: PWY-7216;Reactome: R-HSA-77310;MetaCyc: PWY-6946;KEGG: 00903+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17;MetaCyc: PWY-7656;MetaCyc: PWY-7094;MetaCyc: PWY-7726;MetaCyc: PWY-6863;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.211;MetaCyc: PWY-5177;MetaCyc: PWY-7401;MetaCyc: PWY-6583;MetaCyc: PWY-7007;MetaCyc: PWY-6883;Reactome: R-HSA-77288;KEGG: 00592+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17;KEGG: 00380+4.2.1.17;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17;Reactome: R-HSA-77348;MetaCyc: PWY-7778;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;Reactome: R-HSA-77346;MetaCyc: PWY-5136;Reactome: R-HSA-77305;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;MetaCyc: PWY-1361;Reactome: R-HSA-77285;KEGG: 00720+4.2.1.17;MetaCyc: PWY-6435;KEGG: 00280+4.2.1.17;KEGG: 00930+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-6945;KEGG: 00623+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00062+4.2.1.17+1.1.1.35 "Benzoate degradation";"Acyl chain remodeling of CL";"Geraniol degradation";"Aminobenzoate degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Androstenedione degradation";"Fatty acid degradation";"Fermentation to 2-methylbutanoate";"Phenylalanine metabolism";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Butanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Limonene and pinene degradation";"Caprolactam degradation";"Butanoate metabolism";"Spodoptera littoralis pheromone biosynthesis";"Fatty acid salvage";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Pyruvate fermentation to hexanol (engineered)";"Geraniol degradation";"Fatty acid elongation";"Glutaryl-coa degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Pyruvate fermentation to butanol I";"Methyl ketone biosynthesis (engineered)";"Pyruvate fermentation to butanol II (engineered)";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"alpha-Linolenic acid metabolism";"Lysine degradation";"Benzoate degradation";"Tryptophan metabolism";"Carbon fixation pathways in prokaryotes";"Lysine degradation";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"2-methylpropene degradation";"Tryptophan metabolism";"beta-Alanine metabolism";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Fatty acid beta-oxidation II (plant peroxisome)";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Fatty acid degradation";"Methyl tert-butyl ether degradation";"Benzoyl-coa degradation I (aerobic)";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Carbon fixation pathways in prokaryotes";"4-hydroxybenzoate biosynthesis III (plants)";"Valine, leucine and isoleucine degradation";"Caprolactam degradation";"Valine, leucine and isoleucine degradation";"Propanoate metabolism";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Toluene degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid elongation" XP_030033647.1 3 Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596 "Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I" XP_037299279.1 7 MetaCyc: PWY-6737;MetaCyc: PWY-6724;Reactome: R-HSA-6798695;Reactome: R-HSA-70221;MetaCyc: PWY-7238;MetaCyc: PWY-5941;KEGG: 00500+2.4.1.25 "Starch degradation V";"Starch degradation II";"Neutrophil degranulation";"Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II";"Glycogen degradation II";"Starch and sucrose metabolism" XP_030033438.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_030023293.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_030031329.1 12 Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-141444 "RHO GTPases Activate Formins";"HCMV Early Events";"Aggrephagy";"Mitotic Prometaphase";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_037303446.1 3 Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6807505 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"RNA polymerase II transcribes snRNA genes" XP_037294194.1 3 MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217 "Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage" XP_037295622.1 11 Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-418597 "PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"PKA activation";"Purine metabolism";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events" XP_030033080.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037297649.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_037301286.1 12 Reactome: R-HSA-2894862;Reactome: R-HSA-1251985;Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-9013700;Reactome: R-HSA-977225;Reactome: R-HSA-9017802 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"Noncanonical activation of NOTCH3" XP_030038067.2 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037301796.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_037295464.1 3 Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-5250924 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression" XP_030031770.1 7 MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-5461 "Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation" XP_030026249.2 6 MetaCyc: PWY-5686;Reactome: R-HSA-500753;KEGG: 00240+2.4.2.10;KEGG: 00983+2.4.2.10;MetaCyc: PWY-7790;MetaCyc: PWY-7791 "UMP biosynthesis I";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"UMP biosynthesis II";"UMP biosynthesis III" XP_037297108.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_030034609.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-201722 "Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex" XP_030020324.1 2 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis" XP_037293132.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_037299417.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_037295877.1 6 KEGG: 00562+3.1.3.56;MetaCyc: PWY-6362;Reactome: R-HSA-1855183;MetaCyc: PWY-6364;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6363 "Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation" XP_030024341.1 8 Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-174430 "DNA replication initiation";"Polymerase switching";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation" XP_030025807.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030023481.2 1 Reactome: R-HSA-8951664 "Neddylation" XP_030029283.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037302277.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_030035505.2 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" XP_037298658.1 20 MetaCyc: PWY-6837;MetaCyc: PWY-7726;Reactome: R-HSA-9033241;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7858;MetaCyc: PWY-7338;MetaCyc: PWY-6920;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7340;MetaCyc: PWY-7337;MetaCyc: PWY-735;MetaCyc: PWY-7291;MetaCyc: PWY-7288;MetaCyc: PWY-7574;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6;MetaCyc: PWY-5136;KEGG: 00410+1.3.3.6 "Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(5Z)-dodecenoate biosynthesis II";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoyl-coa degradation II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism" XP_030041299.2 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_030028941.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_030025064.1 18 KEGG: 00350+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00360+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00950+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-6643;MetaCyc: PWY-6642;MetaCyc: PWY-7383;KEGG: 00270+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-5913 "Tyrosine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Alanine, aspartate and glutamate metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Novobiocin biosynthesis";"Sulfolactate degradation III";"Phenylalanine metabolism";"Arginine and proline metabolism";"Arginine biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Isoquinoline alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Coenzyme M biosynthesis II";"(R)-cysteate degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Cysteine and methionine metabolism";"Carbon fixation in photosynthetic organisms";"Partial TCA cycle (obligate autotrophs)" XP_030030936.2 1 Reactome: R-HSA-8949613 "Cristae formation" XP_030038565.2 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_037299451.1 14 MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199 "Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Fatty acid elongation" XP_030024802.2 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_030025802.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_037298097.1 14 Reactome: R-HSA-112043;MetaCyc: PWY-8052;Reactome: R-HSA-4086398;KEGG: 00562+3.1.4.11;Reactome: R-HSA-500657;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;Reactome: R-HSA-434316;MetaCyc: PWY-6351;Reactome: R-HSA-399997;Reactome: R-HSA-418217;MetaCyc: PWY-6367;Reactome: R-HSA-416476;KEGG: 04070+3.1.4.11 "PLC beta mediated events";"2-arachidonoylglycerol biosynthesis";"Ca2+ pathway";"Inositol phosphate metabolism";"Presynaptic function of Kainate receptors";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Acetylcholine regulates insulin secretion";"G beta:gamma signalling through PLC beta";"D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events";"Phosphatidylinositol signaling system" XP_030023014.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_030023447.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037295742.1 4 KEGG: 00270+1.13.11.20;KEGG: 00430+1.13.11.20;Reactome: R-HSA-1614558;MetaCyc: PWY-5331 "Cysteine and methionine metabolism";"Taurine and hypotaurine metabolism";"Degradation of cysteine and homocysteine";"Taurine biosynthesis I" XP_030023655.2 5 KEGG: 00531+3.1.6.14;Reactome: R-HSA-432720;Reactome: R-HSA-2022857;Reactome: R-HSA-6798695;Reactome: R-HSA-2206305 "Glycosaminoglycan degradation";"Lysosome Vesicle Biogenesis";"Keratan sulfate degradation";"Neutrophil degranulation";"MPS IIID - Sanfilippo syndrome D" XP_037298756.1 11 Reactome: R-HSA-164378;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-163359 "PKA activation in glucagon signalling";"PKA activation";"Purine metabolism";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Hedgehog 'off' state";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation" XP_030024547.2 12 MetaCyc: PWY-601;MetaCyc: PWY-801;MetaCyc: PWY-2821;MetaCyc: PWY-6842;MetaCyc: PWY-6309;KEGG: 00270+4.4.1.13;Reactome: R-HSA-71240;MetaCyc: PWY-6936;MetaCyc: PWY-7901;MetaCyc: PWY-1187;KEGG: 00450+4.4.1.13;KEGG: 00380+2.6.1.7 "Glucosinolate biosynthesis from tryptophan";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from phenylalanine";"Glutathione-mediated detoxification II";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Cysteine and methionine metabolism";"Tryptophan catabolism";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from homomethionine";"Selenocompound metabolism";"Tryptophan metabolism" XP_030020371.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_030031453.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556 "Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes" XP_037296678.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030026589.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_037293134.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_030033705.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_030029789.2 7 KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_037300085.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037303447.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-6807505;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"RNA polymerase II transcribes snRNA genes";"Protein ubiquitination" XP_030027335.1 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" XP_037303625.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030030476.1 3 Reactome: R-HSA-1358803;Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037297496.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_030036366.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_030031567.1 10 Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-3108214;Reactome: R-HSA-5693607 "Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"SUMOylation of DNA damage response and repair proteins";"Processing of DNA double-strand break ends" XP_037298840.1 11 KEGG: 00630+6.3.1.2;MetaCyc: PWY-6963;MetaCyc: PWY-381;MetaCyc: PWY-5675;MetaCyc: PWY-6964;Reactome: R-HSA-8964539;KEGG: 00910+6.3.1.2;KEGG: 00250+6.3.1.2;Reactome: R-HSA-210455;MetaCyc: PWY-6549;KEGG: 00220+6.3.1.2 "Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle I";"Nitrate reduction II (assimilatory)";"Nitrate reduction V (assimilatory)";"Ammonia assimilation cycle II";"Glutamate and glutamine metabolism";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"L-glutamine biosynthesis III";"Arginine biosynthesis" XP_037300703.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037301771.1 6 KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039 "Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule" XP_030024524.2 18 MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;MetaCyc: PWY-7417;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482925;Reactome: R-HSA-1482922;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409 "Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Acyl chain remodelling of PS";"Anandamide biosynthesis II";"Synthesis of PA";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PG";"Acyl chain remodelling of PI";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)" XP_037301952.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037294117.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_037293818.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_030029481.2 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_030027165.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins" XP_037303487.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037296996.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins" XP_030021358.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030021481.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-8873719;Reactome: R-HSA-1660499;Reactome: R-HSA-6798695;Reactome: R-HSA-8876198 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RAB geranylgeranylation";"Synthesis of PIPs at the plasma membrane";"Neutrophil degranulation";"RAB GEFs exchange GTP for GDP on RABs" XP_030024164.2 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_030022465.2 3 MetaCyc: PWY-7892;Reactome: R-HSA-6787450;MetaCyc: PWY-7887 "Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion";"Protein SAMPylation and SAMP-mediated thiolation" XP_030029763.2 7 MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-5469 "Justicidin B biosynthesis";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Sesamin biosynthesis" XP_030040919.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_030020995.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_030039805.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_037299321.1 12 MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-6803;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4 "Plasmalogen degradation";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism" XP_037297171.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_030041077.2 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_037298723.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553 "Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs" XP_037293860.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_037301240.1 4 Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_037298560.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_037300147.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_030027069.1 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" XP_037302851.1 1 KEGG: 00230+3.6.1.29 "Purine metabolism" XP_037298735.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_030033760.2 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_030026694.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_037292365.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_030023954.2 12 Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-1169408;Reactome: R-HSA-9010553;Reactome: R-HSA-72662;Reactome: R-HSA-450408;Reactome: R-HSA-429947;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-166208 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"ISG15 antiviral mechanism";"Regulation of expression of SLITs and ROBOs";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Deadenylation of mRNA";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"mTORC1-mediated signalling" XP_030026842.2 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037302311.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_037293020.1 3 Reactome: R-HSA-418457;Reactome: R-HSA-4086398;Reactome: R-HSA-392517 "cGMP effects";"Ca2+ pathway";"Rap1 signalling" XP_037293036.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_030036177.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037295717.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037302149.1 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" XP_037303042.1 24 Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-9648025;Reactome: R-HSA-983189;Reactome: R-HSA-9646399 "Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"MHC class II antigen presentation";"HCMV Early Events";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Recycling pathway of L1";"EML4 and NUDC in mitotic spindle formation";"Kinesins";"Aggrephagy" XP_030028805.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_030036938.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_030020396.2 6 Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-6798695;Reactome: R-HSA-77387 "Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Neutrophil degranulation";"Insulin receptor recycling" XP_030035964.2 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_030034221.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-6433 "Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)" XP_030023275.2 9 KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"Thermogenesis" XP_037300467.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_030026789.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037296865.1 5 Reactome: R-HSA-5649702;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-5685939;Reactome: R-HSA-110381 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through MMEJ (alt-NHEJ)";"Resolution of AP sites via the single-nucleotide replacement pathway" XP_037292616.1 4 KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737;Reactome: R-HSA-70688;MetaCyc: PWY-6922 "Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism";"L-Ndelta-acetylornithine biosynthesis" XP_030024978.1 5 MetaCyc: PWY-7279;MetaCyc: PWY-6692;MetaCyc: PWY-3781;MetaCyc: PWY-7082;KEGG: 00190+7.1.1.8 "Aerobic respiration II (cytochrome c) (yeast)";"Fe(II) oxidation";"Aerobic respiration I (cytochrome c)";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Oxidative phosphorylation" XP_037301025.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037294321.1 3 Reactome: R-HSA-159230;Reactome: R-HSA-77588;Reactome: R-HSA-73856 "Transport of the SLBP Dependant Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination" XP_037297491.1 5 MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)" XP_037294612.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_030026798.2 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_030028758.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_030029025.2 5 Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Late endosomal microautophagy";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_037296082.1 15 Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-2173796;Reactome: R-HSA-6807505;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-176034;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-167238 "Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RNA polymerase II transcribes snRNA genes";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Interactions of Tat with host cellular proteins";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation" XP_037292350.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030020022.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037300942.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037294249.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_030020631.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" YP_001650756.1 7 MetaCyc: PWY-3781;KEGG: 00190+7.1.1.2;Reactome: R-HSA-6799198;Reactome: R-HSA-611105;MetaCyc: PWY-4302;MetaCyc: PWY-5083;MetaCyc: PWY-6692 "Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"Complex I biogenesis";"Respiratory electron transport";"Aerobic respiration III (alternative oxidase pathway)";"NAD/NADH phosphorylation and dephosphorylation";"Fe(II) oxidation" XP_030034190.2 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037298971.1 27 Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-159236 "Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_030032473.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037299975.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_030027287.2 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_030027266.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_030023221.1 1 Reactome: R-HSA-417973 "Adenosine P1 receptors" XP_030036553.1 5 Reactome: R-HSA-9648895;Reactome: R-HSA-8963693;KEGG: 00250+6.3.5.4;Reactome: R-HSA-380994;Reactome: R-HSA-9633012 "Response of EIF2AK1 (HRI) to heme deficiency";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_030031119.2 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_030023208.2 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_030034816.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_030029871.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_030033391.2 4 Reactome: R-HSA-6807505;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "RNA polymerase II transcribes snRNA genes";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037297825.1 5 Reactome: R-HSA-917937;Reactome: R-HSA-2173789;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603 "Iron uptake and transport";"TGF-beta receptor signaling activates SMADs";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"UCH proteinases" XP_037294570.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_030033060.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_037297959.1 2 Reactome: R-HSA-5601884;Reactome: R-HSA-1221632 "PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis" XP_037298347.1 4 Reactome: R-HSA-6794361;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825 "Neurexins and neuroligins";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis" XP_037295363.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_037294900.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_037294425.1 3 Reactome: R-HSA-159230;Reactome: R-HSA-77588;Reactome: R-HSA-73856 "Transport of the SLBP Dependant Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination" XP_030026222.2 24 Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-190840 "Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"Recycling pathway of L1";"Mitotic Prometaphase";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"HCMV Early Events";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane" XP_037297499.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037292261.1 7 KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis" XP_037292322.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_030021597.1 3 MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3 "Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism" XP_037295335.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037295285.1 5 KEGG: 00600+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22 "Sphingolipid metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Galactose metabolism" XP_037295126.1 2 Reactome: R-HSA-9033500;Reactome: R-HSA-9033241 "TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import" XP_030020076.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004 "Clathrin-mediated endocytosis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity" XP_037300739.1 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_030040490.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_037299244.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_030024051.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_037298759.1 2 Reactome: R-HSA-5619039;Reactome: R-HSA-426117 "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters" XP_037297291.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_030036497.1 56 Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-174154 "Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Degradation of DVL";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin" XP_030037872.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037303480.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037298053.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037299096.1 4 Reactome: R-HSA-3371453;Reactome: R-HSA-1268020;Reactome: R-HSA-8950505;Reactome: R-HSA-8949613 "Regulation of HSF1-mediated heat shock response";"Mitochondrial protein import";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Cristae formation" XP_030036936.2 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037295511.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_037303354.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_037297185.1 3 Reactome: R-HSA-2024101;Reactome: R-HSA-2024096;Reactome: R-HSA-2206296 "CS/DS degradation";"HS-GAG degradation";"MPS II - Hunter syndrome" XP_037293730.1 8 Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-3371571 "Macroautophagy";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"mTOR signalling";"HSF1-dependent transactivation" XP_030025178.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_030024744.2 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_037297703.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037300409.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_030027594.2 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5689880 "UCH proteinases";"Ub-specific processing proteases" XP_037296732.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_030028225.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_030033704.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_037294175.1 15 Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700 "Oncogene Induced Senescence";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" XP_030027571.2 1 KEGG: 00240+3.1.3.89 "Pyrimidine metabolism" XP_030020128.2 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037294064.1 8 KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection" XP_030041142.1 4 MetaCyc: PWY-7204;Reactome: R-HSA-964975;MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5 "Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism" XP_030036698.2 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_030029126.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037300151.1 7 MetaCyc: PWY-7255;KEGG: 00480+6.3.2.2;Reactome: R-HSA-174403;MetaCyc: PWY-6840;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.2;Reactome: R-HSA-5578999 "Ergothioneine biosynthesis I (bacteria)";"Glutathione metabolism";"Glutathione synthesis and recycling";"Homoglutathione biosynthesis";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)" XP_037302815.1 6 KEGG: 00720+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;Reactome: R-HSA-71403;KEGG: 00630+4.2.1.3;Reactome: R-HSA-1268020 "Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Citric acid cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Mitochondrial protein import" XP_037298565.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_037297582.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-419037 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions" XP_030027955.2 13 Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706 "Peptide chain elongation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_030032149.1 6 MetaCyc: PWY-5941;MetaCyc: PWY-7238;Reactome: R-HSA-70221;KEGG: 00500+2.4.1.1;MetaCyc: PWY-6731;MetaCyc: PWY-6737 "Glycogen degradation II";"Sucrose biosynthesis II";"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism";"Starch degradation III";"Starch degradation V" XP_030030638.1 56 Reactome: R-HSA-8939902;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-1234176;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-382556;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-4641258;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-983168;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785 "Regulation of RUNX2 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Vpu mediated degradation of CD4";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"ABC-family proteins mediated transport";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Degradation of DVL";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Antigen processing: Ubiquitination & Proteasome degradation";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome" XP_037294543.1 8 Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-5689880;Reactome: R-HSA-8854518 "Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Ub-specific processing proteases";"AURKA Activation by TPX2" XP_030040377.1 8 Reactome: R-HSA-9636467;Reactome: R-HSA-182218;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-167590;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "Blockage of phagosome acidification";"Nef Mediated CD8 Down-regulation";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Nef Mediated CD4 Down-regulation";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_037294302.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_030020899.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_030031107.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030021386.1 3 KEGG: 00970+6.1.1.7;Reactome: R-HSA-379716;Reactome: R-HSA-5368286 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial translation initiation" XP_037294563.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_037298573.1 3 Reactome: R-HSA-174403;MetaCyc: PWY-4041;KEGG: 00480+4.3.2.9 "Glutathione synthesis and recycling";"Gamma-glutamyl cycle";"Glutathione metabolism" XP_037298055.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_037302606.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037302408.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7619 "Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis" XP_037293787.1 3 Reactome: R-HSA-429947;Reactome: R-HSA-380994;Reactome: R-HSA-450604 "Deadenylation of mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA" XP_030037709.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes" XP_037293052.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" YP_001650750.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_030030645.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_030031110.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_030025873.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037301438.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_030041100.2 10 KEGG: 05165+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-201722;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3214847 "Human papillomavirus infection";"Ub-specific processing proteases";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Formation of the beta-catenin:TCF transactivating complex";"Human immunodeficiency virus 1 infection";"HATs acetylate histones" XP_030020501.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030030954.2 9 Reactome: R-HSA-975634;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-4420332;Reactome: R-HSA-2022928 "Retinoid metabolism and transport";"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG biosynthesis" XP_037294725.1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490 "Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation" XP_030019583.2 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_037301817.1 2 MetaCyc: PWY-5697;KEGG: 00230+3.5.3.4 "Allantoin degradation to ureidoglycolate I (urea producing)";"Purine metabolism" XP_030020260.2 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins" XP_037298821.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_030035586.2 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" XP_030025049.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-4085001;Reactome: R-HSA-1660662;Reactome: R-HSA-4341670 "Neutrophil degranulation";"MHC class II antigen presentation";"Sialic acid metabolism";"Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis" XP_030019981.1 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" XP_030040065.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012 "SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_030019982.1 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" XP_037294489.1 6 MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;Reactome: R-HSA-913709 "Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins" XP_030029339.1 6 Reactome: R-HSA-3878781;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;MetaCyc: PWY-7900;Reactome: R-HSA-3322077 "Glycogen storage disease type IV (GBE1)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen synthesis" XP_037299475.1 5 Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2 "Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation" XP_037295272.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_030041072.1 1 Reactome: R-HSA-2173788 "Downregulation of TGF-beta receptor signaling" XP_037298256.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037296563.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_030024960.1 16 Reactome: R-HSA-426496;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-2559580;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-2559585;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408 "Post-transcriptional silencing by small RNAs";"Ca2+ pathway";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oxidative Stress Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Oncogene Induced Senescence";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation" XP_030024928.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_037296852.1 8 MetaCyc: PWY-7765;MetaCyc: PWY-7717;MetaCyc: PWY-6309;KEGG: 00380+3.5.1.9;MetaCyc: PWY-7733;KEGG: 00630+3.5.1.9;MetaCyc: PWY-7734;MetaCyc: PWY-5651 "3-hydroxy-4-methyl-anthranilate biosynthesis II";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"3-hydroxyquinaldate biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Quinoxaline-2-carboxylate biosynthesis";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde" XP_037294712.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037296543.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-6783310;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Fanconi Anemia Pathway";"Protein ubiquitination" XP_037297748.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_037301768.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_037298505.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_037298344.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030020763.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_030035183.2 8 Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-68952 "Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Polymerase switching";"DNA replication initiation" XP_030034771.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030023205.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_030041036.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_037294730.1 13 Reactome: R-HSA-5607763;Reactome: R-HSA-2871809;Reactome: R-HSA-5578775;Reactome: R-HSA-381676;Reactome: R-HSA-4086398;Reactome: R-HSA-114508;Reactome: R-HSA-139853;Reactome: R-HSA-2029485;Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-422356;Reactome: R-HSA-5218921;Reactome: R-HSA-1489509 "CLEC7A (Dectin-1) induces NFAT activation";"FCERI mediated Ca+2 mobilization";"Ion homeostasis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway";"Effects of PIP2 hydrolysis";"Elevation of cytosolic Ca2+ levels";"Role of phospholipids in phagocytosis";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Regulation of insulin secretion";"VEGFR2 mediated cell proliferation";"DAG and IP3 signaling" XP_037294011.1 4 KEGG: 00250+6.3.4.4;MetaCyc: PWY-7219;KEGG: 00230+6.3.4.4;Reactome: R-HSA-73817 "Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis" XP_037293483.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection" XP_030032129.1 18 Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;MetaCyc: PWY-7511;Reactome: R-HSA-3108214;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-912446;Reactome: R-HSA-1221632;Reactome: R-HSA-5685942;Reactome: R-HSA-6796648;Reactome: R-HSA-5689901;Reactome: R-HSA-5693554;Reactome: R-HSA-8953750 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Meiotic recombination";"Meiotic synapsis";"HDR through Homologous Recombination (HRR)";"TP53 Regulates Transcription of DNA Repair Genes";"Metalloprotease DUBs";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Transcriptional Regulation by E2F6" XP_037301799.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_030024010.2 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_030020884.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_037299865.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_030026828.2 14 KEGG: 00564+3.1.3.4;MetaCyc: PWY-8053;Reactome: R-HSA-1483191;KEGG: 00600+3.1.3.4;Reactome: R-HSA-4419969;MetaCyc: PWY-8052;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-6453;Reactome: R-HSA-1483213;KEGG: 00561+3.1.3.4;MetaCyc: PWY-7782;Reactome: R-HSA-75109 "Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Synthesis of PC";"Sphingolipid metabolism";"Depolymerisation of the Nuclear Lamina";"2-arachidonoylglycerol biosynthesis";"Ether lipid metabolism";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Synthesis of PE";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Triglyceride biosynthesis" XP_030023560.2 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_030030238.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037294834.1 2 Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_037293152.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_030034686.2 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_037303228.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_030021419.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518 "Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2" XP_037301415.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_037293018.1 6 Reactome: R-HSA-191273;MetaCyc: PWY-922;Reactome: R-HSA-2426168;KEGG: 00900+4.1.1.33;Reactome: R-HSA-446199;MetaCyc: PWY-7391 "Cholesterol biosynthesis";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Synthesis of Dolichyl-phosphate";"Isoprene biosynthesis II (engineered)" XP_030038162.2 14 Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7724 "Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_030029414.2 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_030036874.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_030020165.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_030037865.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037295446.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-8949215 "Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport" XP_030031957.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_030033316.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_030023368.1 20 Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-176187;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-5656169;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5651801;Reactome: R-HSA-6804756;Reactome: R-HSA-5655862;Reactome: R-HSA-69473;Reactome: R-HSA-5685938 "Translesion synthesis by REV1";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Polymerase switching";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Termination of translesion DNA synthesis";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLK";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)" XP_030020540.2 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_030022793.1 3 Reactome: R-HSA-2022854;Reactome: R-HSA-5173105;Reactome: R-HSA-5083627 "Keratan sulfate biosynthesis";"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6" XP_037296982.1 3 Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154 "Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase" XP_030022276.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037298533.1 19 MetaCyc: PWY-7176;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7205;Reactome: R-HSA-380320;MetaCyc: PWY-7197;MetaCyc: PWY-7224;MetaCyc: PWY-7210;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7221;Reactome: R-HSA-380270;MetaCyc: PWY-7198;MetaCyc: PWY-6545;MetaCyc: PWY-7220;MetaCyc: PWY-7184;MetaCyc: PWY-7226;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7187 "UTP and CTP de novo biosynthesis";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Recruitment of NuMA to mitotic centrosomes";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Recruitment of mitotic centrosome proteins and complexes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II" XP_030033548.2 5 KEGG: 00860+4.1.1.37;MetaCyc: PWY-7159;MetaCyc: PWY-7766;MetaCyc: PWY-5531;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme b biosynthesis IV (Gram-positive bacteria)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Heme biosynthesis" XP_030040236.1 19 KEGG: 00020+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-5392;KEGG: 00630+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-6728;KEGG: 00680+1.1.1.37;Reactome: R-HSA-70263;Reactome: R-HSA-71403;MetaCyc: PWY-7115;MetaCyc: PWY-561;MetaCyc: PWY-7383;KEGG: 00710+1.1.1.37;MetaCyc: PWY-8086;KEGG: 00620+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-5690 "Citrate cycle (TCA cycle)";"Formaldehyde assimilation I (serine pathway)";"Reductive TCA cycle II";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Methane metabolism";"Gluconeogenesis";"Citric acid cycle (TCA cycle)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Superpathway of glyoxylate cycle and fatty acid degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation in photosynthetic organisms";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Cysteine and methionine metabolism";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)" XP_037302232.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_030035972.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037300497.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030031717.1 9 Reactome: R-HSA-6782135;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-8951664 "Dual incision in TC-NER";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Neddylation" XP_037297418.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030029837.2 12 MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-6803;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4 "Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism" XP_037294629.1 29 Reactome: R-HSA-77075;Reactome: R-HSA-167161;Reactome: R-HSA-167200;Reactome: R-HSA-73772;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-6781827;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-73863;Reactome: R-HSA-5696395;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-73776;Reactome: R-HSA-5696400 "RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Termination";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Promoter Escape";"Dual Incision in GG-NER" XP_037303582.1 27 Reactome: R-HSA-180910;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379 "Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events" XP_037295422.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_037294410.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862 "NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_037301896.1 5 KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22 "Galactose metabolism";"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Sphingolipid metabolism" XP_037300610.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030036908.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_037300356.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_030030941.2 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_030031108.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030032282.1 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_037301177.1 3 Reactome: R-HSA-1660517;Reactome: R-HSA-1660514;Reactome: R-HSA-1660516 "Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane" XP_030030607.2 17 KEGG: 00020+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-5392;KEGG: 00630+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-6728;KEGG: 00680+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-561;MetaCyc: PWY-7383;MetaCyc: PWY-8086;KEGG: 00710+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-5690 "Citrate cycle (TCA cycle)";"Formaldehyde assimilation I (serine pathway)";"Reductive TCA cycle II";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Methane metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Superpathway of glyoxylate cycle and fatty acid degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation in photosynthetic organisms";"Pyruvate metabolism";"Cysteine and methionine metabolism";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)" XP_030034174.2 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_030037274.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_030026624.1 2 Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" XP_037303337.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037294461.1 13 Reactome: R-HSA-6802952;Reactome: R-HSA-5674135;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6802948;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6802946;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948 "Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Signaling by high-kinase activity BRAF mutants";"Human papillomavirus infection";"Signaling by moderate kinase activity BRAF mutants";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants" XP_030025268.2 4 MetaCyc: PWY-8026;KEGG: 00100+1.3.1.72;Reactome: R-HSA-6807047;Reactome: R-HSA-6807062 "Sterol biosynthesis (methylotrophs)";"Steroid biosynthesis";"Cholesterol biosynthesis via desmosterol";"Cholesterol biosynthesis via lathosterol" XP_030034418.1 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" XP_037301682.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_037295471.1 20 MetaCyc: PWY-7338;MetaCyc: PWY-6920;MetaCyc: PWY-7854;MetaCyc: PWY-7858;MetaCyc: PWY-7337;MetaCyc: PWY-7340;MetaCyc: PWY-7007;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6837;KEGG: 00592+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7726;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-735;MetaCyc: PWY-7288 "10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(5Z)-dodecenoate biosynthesis II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"alpha-Linolenic acid metabolism";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation VII (yeast peroxisome)" XP_030020533.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73776 "Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape" XP_037301005.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_037298822.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_037297428.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2 "VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway" XP_037292857.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030026662.1 14 MetaCyc: PWY-6886;MetaCyc: PWY-5723;MetaCyc: PWY-7218;MetaCyc: PWY-7124;KEGG: 00010+4.2.1.11;MetaCyc: PWY-1622;MetaCyc: PWY-1042;KEGG: 00680+4.2.1.11;MetaCyc: PWY-7003;MetaCyc: PWY-6142;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-2221;MetaCyc: PWY-8004 "1-butanol autotrophic biosynthesis (engineered)";"Rubisco shunt";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Ethylene biosynthesis V (engineered)";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I" XP_030027157.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_030034273.2 7 Reactome: R-HSA-389661;Reactome: R-HSA-71403;KEGG: 00380+2.3.1.61;Reactome: R-HSA-71064;KEGG: 00310+2.3.1.61;KEGG: 00020+2.3.1.61;MetaCyc: PWY-5084 "Glyoxylate metabolism and glycine degradation";"Citric acid cycle (TCA cycle)";"Tryptophan metabolism";"Lysine catabolism";"Lysine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_037292247.1 5 Reactome: R-HSA-3928662;Reactome: R-HSA-5218921;Reactome: R-HSA-5658442;Reactome: R-HSA-186763;Reactome: R-HSA-8849471 "EPHB-mediated forward signaling";"VEGFR2 mediated cell proliferation";"Regulation of RAS by GAPs";"Downstream signal transduction";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases" XP_030033048.1 10 Reactome: R-HSA-1445148;Reactome: R-HSA-163680;Reactome: R-HSA-380972;Reactome: R-HSA-200425;Reactome: R-HSA-2151209;Reactome: R-HSA-1632852;Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;Reactome: R-HSA-5628897;Reactome: R-HSA-9613354 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"Carnitine metabolism";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Macroautophagy";"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Metabolic Genes";"Lipophagy" XP_030019636.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_030041149.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_030025283.2 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_030022678.1 4 MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817 "Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis" XP_030034446.2 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_030034485.1 3 Reactome: R-HSA-212676;Reactome: R-HSA-9609736;Reactome: R-HSA-6794361 "Dopamine Neurotransmitter Release Cycle";"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins" XP_037293551.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037303570.1 12 Reactome: R-HSA-73762;Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-5250924;Reactome: R-HSA-3214847;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-8941856;Reactome: R-HSA-350054;Reactome: R-HSA-1912408 "RNA Polymerase I Transcription Initiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"B-WICH complex positively regulates rRNA expression";"HATs acetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation" XP_030023563.2 2 Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_037296832.1 11 Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167243 "Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery" XP_030024756.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_030020624.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9010553 "Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs" XP_030028164.2 4 Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_037296142.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030026246.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_037299929.1 2 Reactome: R-HSA-6783984;Reactome: R-HSA-389661 "Glycine degradation";"Glyoxylate metabolism and glycine degradation" XP_030026703.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_030029888.2 5 Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73863 "RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination" XP_030028451.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037302221.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_030035196.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_037300394.1 4 KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;MetaCyc: PWY-7193 "Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I" XP_030020098.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_030029582.2 6 MetaCyc: PWY-6898;Reactome: R-HSA-196819;MetaCyc: PWY-6907;KEGG: 00730+2.7.6.2;MetaCyc: PWY-7356;MetaCyc: PWY-6908 "Thiamine salvage III";"Vitamin B1 (thiamin) metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine metabolism";"Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis IV (eukaryotes)" XP_037295516.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_030029360.2 2 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Synthesis of PG";"Synthesis of PA" XP_030020512.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_030035245.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_030031096.2 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_037300171.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030026826.2 14 KEGG: 00565+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-8051;Reactome: R-HSA-1483213;MetaCyc: PWY-6453;KEGG: 00561+3.1.3.4;MetaCyc: PWY-7782;Reactome: R-HSA-75109;MetaCyc: PWY-8053;KEGG: 00564+3.1.3.4;Reactome: R-HSA-1483191;KEGG: 00600+3.1.3.4;Reactome: R-HSA-4419969;MetaCyc: PWY-8052 "Ether lipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Synthesis of PE";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Triglyceride biosynthesis";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Synthesis of PC";"Sphingolipid metabolism";"Depolymerisation of the Nuclear Lamina";"2-arachidonoylglycerol biosynthesis" XP_037301034.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_037292977.1 5 MetaCyc: PWY-5083;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-7269 "NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_030031775.1 7 MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469 "Justicidin B biosynthesis";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis" XP_037292266.1 7 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_030027902.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_037294769.1 3 Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691 "Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_037294306.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_030025016.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_030022274.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030030440.1 12 KEGG: 00670+2.1.2.9;KEGG: 00230+6.3.4.13;KEGG: 00230+6.3.3.1;Reactome: R-HSA-196780;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.2;MetaCyc: PWY-6613;KEGG: 00970+2.1.2.9;KEGG: 00230+2.1.2.2;MetaCyc: PWY-6121;MetaCyc: PWY-6277;MetaCyc: PWY-6122 "One carbon pool by folate";"Purine metabolism";"Purine metabolism";"Biotin transport and metabolism";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Aminoacyl-tRNA biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II" XP_030022845.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037301255.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_037295514.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_030026402.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-113507 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation" XP_030026256.1 11 Reactome: R-HSA-3214858;Reactome: R-HSA-400206;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-6804114;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-9018519;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201 "RMTs methylate histone arginines";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Estrogen-dependent gene expression";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis" XP_030036082.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037292749.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037294847.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_037300268.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_030027593.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_030020378.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037296495.1 6 Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-416476 "Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events" XP_030023662.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72764 "Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Eukaryotic Translation Termination" XP_037292683.1 3 KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1 "Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"Cyanoamino acid metabolism" XP_030032914.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_030027059.2 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_030027358.2 5 MetaCyc: PWY-4983;KEGG: 00220+1.14.13.39;Reactome: R-HSA-392154;KEGG: 00330+1.14.13.39;Reactome: R-HSA-1222556 "Nitric oxide biosynthesis II (mammals)";"Arginine biosynthesis";"Nitric oxide stimulates guanylate cyclase";"Arginine and proline metabolism";"ROS and RNS production in phagocytes" XP_030028797.1 2 Reactome: R-HSA-8854518;Reactome: R-HSA-6804756 "AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation" XP_037294598.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037300127.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037294695.1 5 Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-983170 "Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" XP_037299296.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556 "Insulin receptor recycling";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes" XP_037296888.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_030031604.2 2 Reactome: R-HSA-611105;Reactome: R-HSA-8876725 "Respiratory electron transport";"Protein methylation" XP_030040427.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030033759.1 3 Reactome: R-HSA-418597;Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13 "G alpha (z) signalling events";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system" XP_037302002.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037292841.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_030021038.1 8 Reactome: R-HSA-8866652;Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-6782210;Reactome: R-HSA-8948747;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135 "Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Ub-specific processing proteases";"Regulation of TP53 Degradation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of PTEN localization";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER" XP_030021568.2 40 MetaCyc: PWY-7007;MetaCyc: PWY-6883;MetaCyc: PWY-6583;MetaCyc: PWY-7401;MetaCyc: PWY-5177;MetaCyc: PWY-7656;MetaCyc: PWY-7094;MetaCyc: PWY-7726;MetaCyc: PWY-6863;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;MetaCyc: PWY-6946;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;MetaCyc: PWY-5138;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6944;MetaCyc: PWY-7654;MetaCyc: PWY-5109;KEGG: 00360+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-6945;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;MetaCyc: PWY-1361;MetaCyc: PWY-6435;KEGG: 00410+4.2.1.17;MetaCyc: PWY-5136;MetaCyc: PWY-7778;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35 "Methyl ketone biosynthesis (engineered)";"Pyruvate fermentation to butanol II (engineered)";"Pyruvate fermentation to butanol I";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Glutaryl-coa degradation";"Spodoptera littoralis pheromone biosynthesis";"Fatty acid salvage";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Pyruvate fermentation to hexanol (engineered)";"Geraniol degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Caprolactam degradation";"Limonene and pinene degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Butanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Aminobenzoate degradation";"Androstenedione degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fermentation to 2-methylbutanoate";"Phenylalanine metabolism";"Benzoate degradation";"Fatty acid elongation";"Toluene degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Valine, leucine and isoleucine degradation";"Propanoate metabolism";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fatty acid degradation";"Methyl tert-butyl ether degradation";"Benzoyl-coa degradation I (aerobic)";"4-hydroxybenzoate biosynthesis III (plants)";"beta-Alanine metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"2-methylpropene degradation";"Tryptophan metabolism";"Carbon fixation pathways in prokaryotes";"alpha-Linolenic acid metabolism";"Lysine degradation" XP_030024197.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_030033206.2 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_030027965.2 5 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-5617472;Reactome: R-HSA-3769402 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex" XP_030027832.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_030028765.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_030020397.2 6 Reactome: R-HSA-77387;Reactome: R-HSA-6798695;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "Insulin receptor recycling";"Neutrophil degranulation";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport" XP_037295914.1 3 Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-381038 "Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"XBP1(S) activates chaperone genes" XP_037292372.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_037297031.1 7 MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469 "Justicidin B biosynthesis";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis" XP_037299655.1 6 Reactome: R-HSA-4793952;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143 "Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis" XP_030019687.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030024750.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037302648.1 3 Reactome: R-HSA-5696394;Reactome: R-HSA-5689877;Reactome: R-HSA-5696395 "DNA Damage Recognition in GG-NER";"Josephin domain DUBs";"Formation of Incision Complex in GG-NER" XP_037298708.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_030031674.1 17 Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-6790901;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553 "Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"rRNA modification in the nucleus and cytosol";"Viral mRNA Translation";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs" XP_030030576.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030040128.1 1 Reactome: R-HSA-2514859 "Inactivation, recovery and regulation of the phototransduction cascade" XP_037303444.1 3 Reactome: R-HSA-6807505;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "RNA polymerase II transcribes snRNA genes";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037302706.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037300361.1 27 Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214 "Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins" XP_037297749.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_037292667.1 4 MetaCyc: PWY-6922;Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737 "L-Ndelta-acetylornithine biosynthesis";"Proline catabolism";"Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis" XP_037292352.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_030040813.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_037293259.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037299978.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_037294843.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_030024200.2 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037294835.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037293930.1 7 KEGG: 00310+2.3.1.61;KEGG: 00020+2.3.1.61;MetaCyc: PWY-5084;Reactome: R-HSA-389661;Reactome: R-HSA-71403;KEGG: 00380+2.3.1.61;Reactome: R-HSA-71064 "Lysine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citric acid cycle (TCA cycle)";"Tryptophan metabolism";"Lysine catabolism" XP_037303088.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_030028873.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_030029634.1 3 Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_030024764.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030034614.2 6 Reactome: R-HSA-5632987;Reactome: R-HSA-5545483;Reactome: R-HSA-6796648;Reactome: R-HSA-5358606;Reactome: R-HSA-912446;Reactome: R-HSA-5358565 "Defective Mismatch Repair Associated With PMS2";"Defective Mismatch Repair Associated With MLH1";"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)" XP_030034290.2 1 Reactome: R-HSA-264876 "Insulin processing" XP_037292689.1 6 Reactome: R-HSA-6803207;Reactome: R-HSA-6803211;Reactome: R-HSA-6803204;Reactome: R-HSA-6804759;Reactome: R-HSA-139915;Reactome: R-HSA-6803205 "TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Regulation of TP53 Activity through Association with Co-factors";"Activation of PUMA and translocation to mitochondria";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain" XP_030028432.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_030040982.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_030020240.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030039546.1 9 Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-76042 "RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_030038409.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030034078.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_037303372.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_030023479.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_037297287.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_030019941.1 29 Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-73772;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-167161;Reactome: R-HSA-73863;Reactome: R-HSA-5696395;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-76042;Reactome: R-HSA-6781823;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-167152;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-73776;Reactome: R-HSA-5696400;Reactome: R-HSA-167158 "Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation";"RNA Polymerase I Transcription Termination";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"RNA Polymerase II Promoter Escape";"Dual Incision in GG-NER";"Formation of the HIV-1 Early Elongation Complex" XP_030041234.1 3 KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048 "Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG" XP_037300275.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_037303466.1 6 MetaCyc: PWY-6367;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.64+3.1.3.95;MetaCyc: PWY-6580;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.64+3.1.3.95 "D-myo-inositol-5-phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Phosphatidylinositol biosynthesis I (bacteria)";"3-phosphoinositide degradation";"Inositol phosphate metabolism" XP_037294745.1 11 Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-418555 "Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Purine metabolism";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events" XP_030022119.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037292944.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320 "Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes" XP_037301478.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_037295410.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_030024868.2 16 Reactome: R-HSA-9018519;Reactome: R-HSA-3214847;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693548;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565 "Estrogen-dependent gene expression";"HATs acetylate histones";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Sensing of DNA Double Strand Breaks";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_037300850.1 9 Reactome: R-HSA-69205;Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-113501 "G1/S-Specific Transcription";"Removal of the Flap Intermediate";"Polymerase switching";"Activation of the pre-replicative complex";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1" XP_030024686.1 4 Reactome: R-HSA-8953750;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-69656 "Transcriptional Regulation by E2F6";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry" XP_030020586.1 3 Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894 "Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation" XP_037300605.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037294482.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_030022753.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_030021451.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037296128.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_037298983.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_037294889.1 4 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315;KEGG: 00908+2.5.1.75;MetaCyc: PWY-2781 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol";"Zeatin biosynthesis";"Cis-zeatin biosynthesis" XP_030024478.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037302486.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_037292729.1 27 Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-170822;Reactome: R-HSA-3371453 "tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response" XP_030033238.2 2 KEGG: 00500+3.2.1.26;KEGG: 00052+3.2.1.26 "Starch and sucrose metabolism";"Galactose metabolism" XP_037296152.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030033762.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_030022482.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037300611.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037299195.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_030036661.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030024629.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_037300253.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_030036703.2 57 Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-5610783 "Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"UCH proteinases";"Vpu mediated degradation of CD4";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome" XP_037297194.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes" XP_037292845.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_030026223.2 24 Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257 "The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"Mitotic Prometaphase";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"MHC class II antigen presentation";"HCMV Early Events";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion" XP_030023801.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037295917.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037296279.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" XP_037293431.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection" XP_030030699.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_037292433.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955 "RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation" XP_030024728.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_030022483.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_030035433.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_030033191.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_030023788.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_037293856.1 33 Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-68877;Reactome: R-HSA-180746 "SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"RHO GTPases Activate Formins";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"Mitotic Prometaphase";"Nuclear import of Rev protein" XP_037300976.1 5 MetaCyc: PWY-6855;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;Reactome: R-HSA-189085 "Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate" XP_037297443.1 3 Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2 "Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway" XP_037293855.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_037302110.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_037299379.1 2 KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_037298677.1 16 KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198;Reactome: R-HSA-1614558;MetaCyc: PWY-7184;MetaCyc: PWY-7220;MetaCyc: PWY-6545;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7222;Reactome: R-HSA-499943;Reactome: R-HSA-1614603;KEGG: 00230+1.17.4.1;KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1;Reactome: R-HSA-2408508;MetaCyc: PWY-7210 "Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Degradation of cysteine and homocysteine";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Cysteine formation from homocysteine";"Purine metabolism";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" XP_030023284.2 9 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674400 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Constitutive Signaling by AKT1 E17K in Cancer" XP_030026787.2 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_030037736.2 1 Reactome: R-HSA-8949613 "Cristae formation" XP_030023673.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037296853.1 2 Reactome: R-HSA-2022377;Reactome: R-HSA-6798695 "Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation" XP_030038281.2 3 Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394 "Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER" XP_030023521.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_030028786.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_030041006.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037297351.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_030030995.1 15 Reactome: R-HSA-5693548;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-5685939;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-5693554 "Sensing of DNA Double Strand Breaks";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"HDR through MMEJ (alt-NHEJ)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_037300862.1 4 Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_030022383.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557 "Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis" XP_030023043.1 8 Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68827 "Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex" XP_037303280.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037299609.1 2 MetaCyc: PWY-6558;Reactome: R-HSA-2022928 "Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis" XP_030020686.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_030035968.2 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" YP_001650753.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_030027898.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" XP_030034842.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_030033702.2 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_037292284.1 1 Reactome: R-HSA-9617828 "FOXO-mediated transcription of cell cycle genes" XP_030028888.2 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_030027812.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_030026607.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" XP_037295873.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_030027035.2 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_030025311.1 29 Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-73863;Reactome: R-HSA-5696395;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-76042;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-73772;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-167161;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-5696400;Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-75955;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-6782210 "Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Termination";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual Incision in GG-NER";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_030033681.2 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_030038273.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030029851.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030035025.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037300148.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_030030670.1 2 Reactome: R-HSA-446193;Reactome: R-HSA-4570571 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)" XP_030026821.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes" XP_030027274.1 2 Reactome: R-HSA-2142700;Reactome: R-HSA-2142691 "Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_030022240.2 8 MetaCyc: PWY-5651;KEGG: 00630+3.5.1.9;KEGG: 00380+3.5.1.9;MetaCyc: PWY-7733;MetaCyc: PWY-6309;MetaCyc: PWY-7734;MetaCyc: PWY-7717;MetaCyc: PWY-7765 "L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Glyoxylate and dicarboxylate metabolism";"Tryptophan metabolism";"3-hydroxyquinaldate biosynthesis";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Quinoxaline-2-carboxylate biosynthesis";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"3-hydroxy-4-methyl-anthranilate biosynthesis II" XP_037296714.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_030022211.1 25 Reactome: R-HSA-432040;Reactome: R-HSA-416476;Reactome: R-HSA-202040;Reactome: R-HSA-428930;Reactome: R-HSA-418597;Reactome: R-HSA-500657;Reactome: R-HSA-381771;Reactome: R-HSA-420092;Reactome: R-HSA-400042;Reactome: R-HSA-8964616;Reactome: R-HSA-4086398;Reactome: R-HSA-381676;Reactome: R-HSA-456926;Reactome: R-HSA-418217;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-392170;Reactome: R-HSA-416482;Reactome: R-HSA-163359;Reactome: R-HSA-392851;Reactome: R-HSA-418592;Reactome: R-HSA-418555;Reactome: R-HSA-9009391;Reactome: R-HSA-8964315;Reactome: R-HSA-392451 "Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (q) signalling events";"G-protein activation";"Thromboxane signalling through TP receptor";"G alpha (z) signalling events";"Presynaptic function of Kainate receptors";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Glucagon-type ligand receptors";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through CDC42";"Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through PLC beta";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"ADP signalling through P2Y purinoceptor 12";"G alpha (12/13) signalling events";"Glucagon signaling in metabolic regulation";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 1";"G alpha (s) signalling events";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through BTK";"G beta:gamma signalling through PI3Kgamma" XP_030028300.2 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037295109.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-8876198 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_037294747.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037296154.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037298444.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_030032935.1 4 Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957 "Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_037292356.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037300130.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_030035868.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_030026565.2 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_037295383.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_030041017.1 3 Reactome: R-HSA-430039;Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_037298611.1 14 MetaCyc: PWY-8051;MetaCyc: PWY-8055;Reactome: R-HSA-1483213;MetaCyc: PWY-6453;KEGG: 00565+3.1.3.4;Reactome: R-HSA-75109;KEGG: 00561+3.1.3.4;MetaCyc: PWY-7782;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8053;Reactome: R-HSA-1483191;Reactome: R-HSA-4419969;MetaCyc: PWY-8052;KEGG: 00600+3.1.3.4 "Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PE";"Stigma estolide biosynthesis";"Ether lipid metabolism";"Triglyceride biosynthesis";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Synthesis of PC";"Depolymerisation of the Nuclear Lamina";"2-arachidonoylglycerol biosynthesis";"Sphingolipid metabolism" XP_037293247.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_037292268.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway" XP_030038768.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_030026507.2 13 MetaCyc: PWY-7182;MetaCyc: PWY-7410;MetaCyc: PWY-7141;MetaCyc: PWY-7102;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-5123;MetaCyc: PWY-5122;MetaCyc: PWY-7736;MetaCyc: PWY-6859;MetaCyc: PWY-7709;MetaCyc: PWY-6383;MetaCyc: PWY-7721;MetaCyc: PWY-7659 "Linalool biosynthesis I";"Ipsdienol biosynthesis";"(3S)-linalool biosynthesis";"Bisabolene biosynthesis (engineered)";"Terpenoid backbone biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Geranyl diphosphate biosynthesis";"Stellatic acid biosynthesis";"All-trans-farnesol biosynthesis";"(3R)-linalool biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"Viridicatumtoxin biosynthesis" XP_030037897.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037298562.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_037293758.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_030037441.2 6 KEGG: 00040+1.1.1.22;KEGG: 00053+1.1.1.22;KEGG: 00520+1.1.1.22;MetaCyc: PWY-7820;MetaCyc: PWY-7346;Reactome: R-HSA-173599 "Pentose and glucuronate interconversions";"Ascorbate and aldarate metabolism";"Amino sugar and nucleotide sugar metabolism";"Teichuronic acid biosynthesis (B. subtilis 168)";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Formation of the active cofactor, UDP-glucuronate" XP_030021234.1 6 Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-6798695;Reactome: R-HSA-77387 "Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Neutrophil degranulation";"Insulin receptor recycling" XP_030033081.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_030027911.1 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" XP_037302177.1 24 Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-9648025;Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-1445148 "Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"Aggrephagy";"Mitotic Prometaphase";"Recycling pathway of L1";"EML4 and NUDC in mitotic spindle formation";"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"Cilium Assembly";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_037296715.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_037293692.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037294192.1 3 MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217 "Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage" XP_037292839.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_030028408.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_037298957.1 1 Reactome: R-HSA-8950505 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_030034099.1 2 Reactome: R-HSA-3299685;Reactome: R-HSA-211945 "Detoxification of Reactive Oxygen Species";"Phase I - Functionalization of compounds" XP_037295712.1 4 MetaCyc: PWY-8072;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8040;MetaCyc: PWY-7383 "Alanine racemization";"D-Alanine metabolism";"Ansatrienin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_037299242.1 7 Reactome: R-HSA-2151201;Reactome: R-HSA-8949613;Reactome: R-HSA-163210;MetaCyc: PWY-7980;Reactome: R-HSA-1268020;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2 "Transcriptional activation of mitochondrial biogenesis";"Cristae formation";"Formation of ATP by chemiosmotic coupling";"ATP biosynthesis";"Mitochondrial protein import";"Oxidative phosphorylation";"Photosynthesis" XP_037296620.1 7 MetaCyc: PWY-7839;Reactome: R-HSA-1660662;MetaCyc: PWY-7838;MetaCyc: PWY-7836;MetaCyc: PWY-7841;MetaCyc: PWY-5129;KEGG: 00600+2.4.1.80 "Lacto-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Globo-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism" XP_030026595.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_030028591.2 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" XP_030025863.1 2 Reactome: R-HSA-1566948;Reactome: R-HSA-2243919 "Elastic fibre formation";"Crosslinking of collagen fibrils" XP_037299147.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037302740.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_030021926.2 3 Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646 "Defective ACY1 causes encephalopathy";"Arginine biosynthesis";"Aflatoxin activation and detoxification" XP_037293752.1 4 Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955 "E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation" XP_030025819.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-191859 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"snRNP Assembly" XP_030034160.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037298375.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_037292913.1 7 KEGG: 00010+2.3.1.12;Reactome: R-HSA-389661;KEGG: 00020+2.3.1.12;KEGG: 00620+2.3.1.12;Reactome: R-HSA-204174;Reactome: R-HSA-5362517;Reactome: R-HSA-70268 "Glycolysis / Gluconeogenesis";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Pyruvate metabolism" XP_037298637.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_030035734.1 2 KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859 "Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade" XP_030034203.2 3 Reactome: R-HSA-1810476;Reactome: R-HSA-933542;Reactome: R-HSA-445989 "RIP-mediated NFkB activation via ZBP1";"TRAF6 mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex" XP_037293944.1 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" XP_030030680.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_030034948.1 3 Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B "Neutrophil degranulation";"Folate biosynthesis";"Glutamate removal from folates" XP_030024125.2 11 MetaCyc: PWY-5675;MetaCyc: PWY-381;MetaCyc: PWY-6963;KEGG: 00630+6.3.1.2;Reactome: R-HSA-210455;KEGG: 00220+6.3.1.2;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6549;KEGG: 00910+6.3.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-6964 "Nitrate reduction V (assimilatory)";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle I";"Glyoxylate and dicarboxylate metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"L-glutamine biosynthesis III";"Nitrogen metabolism";"Glutamate and glutamine metabolism";"Ammonia assimilation cycle II" XP_037295286.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_037293501.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_030031128.2 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_030020575.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_030032153.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_030022081.1 11 Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-418555 "Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Purine metabolism";"PKA activation";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"G alpha (z) signalling events";"G alpha (s) signalling events" XP_030040354.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_030022165.1 3 Reactome: R-HSA-8854214;Reactome: R-HSA-8856828;Reactome: R-HSA-8875656 "TBC/RABGAPs";"Clathrin-mediated endocytosis";"MET receptor recycling" XP_037297326.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037298046.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037300564.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" XP_037299490.1 14 MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7601 "(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_030027524.2 9 Reactome: R-HSA-1483166;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.94;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-6118;MetaCyc: PWY-7385;MetaCyc: PWY-7902 "Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Glycerol-3-phosphate shuttle";"1,3-propanediol biosynthesis (engineered)";"Glucosylglycerol biosynthesis" XP_030030489.1 5 Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-72163 "Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway" XP_030027618.2 6 MetaCyc: PWY-6829;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6787450;MetaCyc: PWY-7286;MetaCyc: PWY-7285 "Trna methylation (yeast)";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis" XP_037299719.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037301559.1 5 Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695 "COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Neutrophil degranulation" XP_037302410.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_030041080.2 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_030041126.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_030032590.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_030040151.2 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037297365.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-3000178 "Protein ubiquitination";"ECM proteoglycans" XP_030023304.2 9 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674400 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Constitutive Signaling by AKT1 E17K in Cancer" XP_030021964.1 3 Reactome: R-HSA-2299718;Reactome: R-HSA-3214841;Reactome: R-HSA-6804760 "Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines";"Regulation of TP53 Activity through Methylation" XP_030037218.2 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_030026790.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037296147.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030036652.2 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_030031414.1 5 Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5689901;Reactome: R-HSA-5693607 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Metalloprotease DUBs";"Processing of DNA double-strand break ends" XP_030029655.2 3 MetaCyc: PWY-8099;KEGG: 00790+4.2.1.96;MetaCyc: PWY-7158 "Tetrahydropteridine recycling";"Folate biosynthesis";"L-phenylalanine degradation V" XP_037292797.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037296548.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_030027281.1 14 Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-141444;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5620912;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Anchoring of the basal body to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_037297974.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_030028005.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_030027827.2 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_030021153.1 2 Reactome: R-HSA-5576886;Reactome: R-HSA-1299308 "Phase 4 - resting membrane potential";"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)" XP_030021879.1 4 Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219 "Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_030032349.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_037301762.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_030022272.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030023660.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_037298587.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_030035274.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030021111.2 56 Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-9020702;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-75815 "Degradation of AXIN";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Interleukin-1 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D" XP_037295448.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_037302423.1 42 Reactome: R-HSA-3214847;Reactome: R-HSA-4551638;Reactome: R-HSA-110330;Reactome: R-HSA-110328;Reactome: R-HSA-171306;Reactome: R-HSA-977225;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-3214841;Reactome: R-HSA-3214815;Reactome: R-HSA-1221632;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-201722;Reactome: R-HSA-3214842;Reactome: R-HSA-110329;Reactome: R-HSA-110331;Reactome: R-HSA-73728;Reactome: R-HSA-2299718;Reactome: R-HSA-5693565;Reactome: R-HSA-212300;Reactome: R-HSA-9616222;Reactome: R-HSA-5250924;Reactome: R-HSA-9018519;Reactome: R-HSA-8939236;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-3214858;Reactome: R-HSA-912446;Reactome: R-HSA-2559582;Reactome: R-HSA-9610379;Reactome: R-HSA-5334118;Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-8936459;Reactome: R-HSA-606279;Reactome: R-HSA-69473;Reactome: R-HSA-73772;Reactome: R-HSA-1912408;Reactome: R-HSA-9609690;Reactome: R-HSA-427389;Reactome: R-HSA-5693571 "HATs acetylate histones";"SUMOylation of chromatin organization proteins";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Packaging Of Telomere Ends";"Amyloid fiber formation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"PKMTs methylate histone lysines";"HDACs deacetylate histones";"Meiotic synapsis";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Formation of the beta-catenin:TCF transactivating complex";"HDMs demethylate histones";"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine";"RNA Polymerase I Promoter Opening";"Condensation of Prophase Chromosomes";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PRC2 methylates histones and DNA";"Transcriptional regulation of granulopoiesis";"B-WICH complex positively regulates rRNA expression";"Estrogen-dependent gene expression";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"RMTs methylate histone arginines";"Meiotic recombination";"Senescence-Associated Secretory Phenotype (SASP)";"HCMV Late Events";"DNA methylation";"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deposition of new CENPA-containing nucleosomes at the centromere";"G2/M DNA damage checkpoint";"RNA Polymerase I Promoter Escape";"Pre-NOTCH Transcription and Translation";"HCMV Early Events";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Nonhomologous End-Joining (NHEJ)" XP_037297587.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation" XP_030022937.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_030026608.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_037302733.1 1 Reactome: R-HSA-2467813 "Separation of Sister Chromatids" XP_030035405.1 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" XP_037302900.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_030020502.2 4 Reactome: R-HSA-975138;Reactome: R-HSA-975871;Reactome: R-HSA-6799198;Reactome: R-HSA-166058 "TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 cascade initiated on plasma membrane";"Complex I biogenesis";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane" XP_030032756.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_037300811.1 9 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-9615710;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-9613829;Reactome: R-HSA-5678895;Reactome: R-HSA-9646399;Reactome: R-HSA-5627083 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Late endosomal microautophagy";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"Chaperone Mediated Autophagy";"Defective CFTR causes cystic fibrosis";"Aggrephagy";"RHO GTPases regulate CFTR trafficking" XP_030028794.1 10 Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-5689880;Reactome: R-HSA-917729;Reactome: R-HSA-8856825;Reactome: R-HSA-432720;Reactome: R-HSA-9636383;Reactome: R-HSA-9635644;Reactome: R-HSA-8856828 "EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Ub-specific processing proteases";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Cargo recognition for clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Prevention of phagosomal-lysosomal fusion";"Inhibition of membrane repair";"Clathrin-mediated endocytosis" XP_037293151.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_030021843.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_037302833.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_030024850.1 24 Reactome: R-HSA-418597;Reactome: R-HSA-420092;Reactome: R-HSA-500657;Reactome: R-HSA-400042;Reactome: R-HSA-4086398;Reactome: R-HSA-381676;Reactome: R-HSA-8964616;Reactome: R-HSA-432040;Reactome: R-HSA-202040;Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-392851;Reactome: R-HSA-163359;Reactome: R-HSA-418592;Reactome: R-HSA-8964315;Reactome: R-HSA-9009391;Reactome: R-HSA-418555;Reactome: R-HSA-392451;Reactome: R-HSA-456926;Reactome: R-HSA-418217;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-416482;Reactome: R-HSA-392170 "G alpha (z) signalling events";"Glucagon-type ligand receptors";"Presynaptic function of Kainate receptors";"Adrenaline,noradrenaline inhibits insulin secretion";"Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through CDC42";"Vasopressin regulates renal water homeostasis via Aquaporins";"G-protein activation";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"Prostacyclin signalling through prostacyclin receptor";"Glucagon signaling in metabolic regulation";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through BTK";"Extra-nuclear estrogen signaling";"G alpha (s) signalling events";"G beta:gamma signalling through PI3Kgamma";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through PLC beta";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (12/13) signalling events";"ADP signalling through P2Y purinoceptor 12" XP_037296729.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_030040880.2 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_030040721.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_037300841.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037298941.1 9 Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-6807505 "RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes" XP_030038958.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_037293659.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_030022891.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_030022275.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037300430.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_030024198.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_037298958.1 1 Reactome: R-HSA-8950505 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_037300537.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_037298574.1 17 Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6790901 "Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"rRNA modification in the nucleus and cytosol" XP_037295433.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" XP_030028986.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037295687.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030037962.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379 "Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"HCMV Late Events" XP_030034479.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_030024401.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030028441.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037299790.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_037300038.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037295533.1 19 Reactome: R-HSA-8856825;Reactome: R-HSA-5686938;Reactome: R-HSA-8866423;Reactome: R-HSA-3000471;Reactome: R-HSA-3000497;Reactome: R-HSA-975634;Reactome: R-HSA-8964046;Reactome: R-HSA-3000484;Reactome: R-HSA-432142;Reactome: R-HSA-8856828;Reactome: R-HSA-8964038;Reactome: R-HSA-8963888;Reactome: R-HSA-8957275;Reactome: R-HSA-3000480;Reactome: R-HSA-381426;Reactome: R-HSA-8963901;Reactome: R-HSA-8964026;Reactome: R-HSA-8964041;Reactome: R-HSA-202733 "Cargo recognition for clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"VLDL assembly";"Scavenging by Class B Receptors";"Scavenging by Class H Receptors";"Retinoid metabolism and transport";"VLDL clearance";"Scavenging by Class F Receptors";"Platelet sensitization by LDL";"Clathrin-mediated endocytosis";"LDL clearance";"Chylomicron assembly";"Post-translational protein phosphorylation";"Scavenging by Class A Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron remodeling";"Chylomicron clearance";"LDL remodeling";"Cell surface interactions at the vascular wall" XP_030020990.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_037293462.1 7 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway" XP_030021377.1 2 Reactome: R-HSA-1912399;KEGG: 00514+2.4.1.221 "Pre-NOTCH Processing in the Endoplasmic Reticulum";"Other types of O-glycan biosynthesis" XP_037299354.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_030019735.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" XP_037294383.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_030033650.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_037293362.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553 "SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs" XP_037298673.1 6 Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs" XP_037300094.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_037294469.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_030024948.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_030026435.1 12 Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-193692;Reactome: R-HSA-3928665;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-977225;Reactome: R-HSA-2894862;Reactome: R-HSA-1251985;Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-2122948 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"EPH-ephrin mediated repulsion of cells";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_030041159.1 4 MetaCyc: PWY-7204;Reactome: R-HSA-964975;MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5 "Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism" XP_037295312.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_030029714.1 8 MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-6142;MetaCyc: PWY-7115;MetaCyc: PWY-5743 "C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle" XP_037298319.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_037300146.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037302542.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_030023573.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_030032453.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism" XP_030026678.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037295114.1 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" XP_037297300.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_030033652.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030020687.1 4 MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822 "Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)" XP_030035894.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649 "Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation" XP_030024403.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_030027161.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins" XP_037294129.1 4 Reactome: R-HSA-5660862;Reactome: R-HSA-210991;Reactome: R-HSA-352230;Reactome: R-HSA-71240 "Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Basigin interactions";"Amino acid transport across the plasma membrane";"Tryptophan catabolism" XP_037297138.1 3 Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import" XP_030024909.1 14 MetaCyc: PWY-3661;KEGG: 00630+2.1.2.1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-3841;MetaCyc: PWY-3661-1;MetaCyc: PWY-1622;MetaCyc: PWY-2201;KEGG: 00260+2.1.2.1;MetaCyc: PWY-181;MetaCyc: PWY-2161;MetaCyc: PWY-5497;Reactome: R-HSA-196757;KEGG: 00680+2.1.2.1;KEGG: 00460+2.1.2.1 "Glycine betaine degradation I";"Glyoxylate and dicarboxylate metabolism";"One carbon pool by folate";"Folate transformations II (plants)";"Glycine betaine degradation II (mammalian)";"Formaldehyde assimilation I (serine pathway)";"Folate transformations I";"Glycine, serine and threonine metabolism";"Photorespiration ";"Folate polyglutamylation";"Purine nucleobases degradation II (anaerobic)";"Metabolism of folate and pterines";"Methane metabolism";"Cyanoamino acid metabolism" XP_037300680.1 1 KEGG: 00230+3.6.1.29 "Purine metabolism" XP_030034175.2 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037302577.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_037298722.1 20 MetaCyc: PWY-7854;MetaCyc: PWY-7858;MetaCyc: PWY-7338;MetaCyc: PWY-6920;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7340;MetaCyc: PWY-7337;MetaCyc: PWY-6837;MetaCyc: PWY-7726;Reactome: R-HSA-9033241;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7574;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-5136;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-735;MetaCyc: PWY-7288 "Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(5Z)-dodecenoate biosynthesis II";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"alpha-Linolenic acid metabolism";"Propanoyl-coa degradation II";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation VII (yeast peroxisome)" XP_030039431.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_037301494.1 9 Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-6804756 "Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation" XP_037298348.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6794361;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958 "Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)" XP_030031150.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_030029165.2 3 MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482 "Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)" XP_037292190.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154 "Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase" XP_037293030.1 2 Reactome: R-HSA-70263;Reactome: R-HSA-70171 "Gluconeogenesis";"Glycolysis" XP_037299879.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-6804758 "HDACs deacetylate histones";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation" XP_037302637.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_030021483.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_030032870.1 6 Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-380994 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_037297016.1 7 MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445 "Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation" XP_030037089.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037300095.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_030034508.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_030021687.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_030022959.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-192823 "Eukaryotic Translation Termination";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation" XP_037301974.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_037292388.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037294603.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037298529.1 1 KEGG: 00970+6.1.1.5 "Aminoacyl-tRNA biosynthesis" XP_030032440.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_030040916.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030030512.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037303363.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_030039832.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_030035343.1 9 Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-1989781;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-191859 "RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"snRNP Assembly" XP_030032569.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_030021919.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_037293547.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_037294684.1 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_037297333.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037295781.1 6 Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-3769402 "Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex" XP_030034883.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037300314.1 13 MetaCyc: PWY-6969;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-5538;KEGG: 00020+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;Reactome: R-HSA-71403;MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"Pyruvate fermentation to acetate V";"Pyruvate fermentation to acetate VI";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes" XP_030026667.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_030036112.1 1 Reactome: R-HSA-8964572 "Lipid particle organization" XP_030040896.2 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_030022879.2 4 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" XP_030031827.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_037301684.1 83 Reactome: R-HSA-5654710;Reactome: R-HSA-1250196;Reactome: R-HSA-210993;Reactome: R-HSA-912526;Reactome: R-HSA-9026519;Reactome: R-HSA-8856825;Reactome: R-HSA-112412;Reactome: R-HSA-8853334;Reactome: R-HSA-9028731;Reactome: R-HSA-1433559;Reactome: R-HSA-5654712;Reactome: R-HSA-8851805;Reactome: R-HSA-5663213;Reactome: R-HSA-180292;Reactome: R-HSA-5655302;Reactome: R-HSA-512988;Reactome: R-HSA-8983432;Reactome: R-HSA-9634285;Reactome: R-HSA-1295596;Reactome: R-HSA-5673001;Reactome: R-HSA-8856828;Reactome: R-HSA-912631;Reactome: R-HSA-6807004;Reactome: R-HSA-5654693;Reactome: R-HSA-2424491;Reactome: R-HSA-1433557;Reactome: R-HSA-9028335;Reactome: R-HSA-5654727;Reactome: R-HSA-2871796;Reactome: R-HSA-5654733;Reactome: R-HSA-5654689;Reactome: R-HSA-5654706;Reactome: R-HSA-5654719;Reactome: R-HSA-167044;Reactome: R-HSA-186763;Reactome: R-HSA-9664565;Reactome: R-HSA-983695;Reactome: R-HSA-9607240;Reactome: R-HSA-8853338;Reactome: R-HSA-1250347;Reactome: R-HSA-109704;Reactome: R-HSA-2871809;Reactome: R-HSA-1839117;Reactome: R-HSA-180336;Reactome: R-HSA-2219530;Reactome: R-HSA-8875555;Reactome: R-HSA-8865999;Reactome: R-HSA-391160;Reactome: R-HSA-74751;Reactome: R-HSA-5654695;Reactome: R-HSA-388841;Reactome: R-HSA-179812;Reactome: R-HSA-8875360;Reactome: R-HSA-2179392;Reactome: R-HSA-182971;Reactome: R-HSA-2730905;Reactome: R-HSA-5655253;Reactome: R-HSA-5654699;Reactome: R-HSA-5654732;Reactome: R-HSA-8875656;Reactome: R-HSA-9027284;Reactome: R-HSA-6811558;Reactome: R-HSA-9645135;Reactome: R-HSA-74749;Reactome: R-HSA-5637810;Reactome: R-HSA-354194;Reactome: R-HSA-1963640;Reactome: R-HSA-1257604;Reactome: R-HSA-389359;Reactome: R-HSA-5654720;Reactome: R-HSA-375165;Reactome: R-HSA-9034864;Reactome: R-HSA-1236382;Reactome: R-HSA-2029482;Reactome: R-HSA-5654704;Reactome: R-HSA-8853659;Reactome: R-HSA-5654688;Reactome: R-HSA-5655291;Reactome: R-HSA-8851907;Reactome: R-HSA-5654726;Reactome: R-HSA-2428933;Reactome: R-HSA-1963642;Reactome: R-HSA-5654700 "PI-3K cascade:FGFR3";"SHC1 events in ERBB2 signaling";"Tie2 Signaling";"Interleukin receptor SHC signaling";"Activated NTRK2 signals through RAS";"Cargo recognition for clathrin-mediated endocytosis";"SOS-mediated signalling";"Signaling by FGFR3 fusions in cancer";"Activated NTRK2 signals through FRS2 and FRS3";"Regulation of KIT signaling";"FRS-mediated FGFR4 signaling";"MET activates RAS signaling";"RHO GTPases Activate WASPs and WAVEs";"GAB1 signalosome";"Signaling by FGFR1 in disease";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Interleukin-15 signaling";"Constitutive Signaling by Overexpressed ERBB2";"Spry regulation of FGF signaling";"RAF/MAP kinase cascade";"Clathrin-mediated endocytosis";"Regulation of signaling by CBL";"Negative regulation of MET activity";"FRS-mediated FGFR1 signaling";"DAP12 signaling";"Signaling by SCF-KIT";"Activated NTRK2 signals through PI3K";"Negative regulation of FGFR2 signaling";"FCERI mediated MAPK activation";"Negative regulation of FGFR4 signaling";"PI-3K cascade:FGFR1";"FRS-mediated FGFR3 signaling";"SHC-mediated cascade:FGFR4";"Signalling to RAS";"Downstream signal transduction";"Signaling by ERBB2 KD Mutants";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FLT3 Signaling";"Signaling by FGFR3 point mutants in cancer";"SHC1 events in ERBB4 signaling";"PI3K Cascade";"FCERI mediated Ca+2 mobilization";"Signaling by cytosolic FGFR1 fusion mutants";"SHC1 events in EGFR signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"MET activates RAP1 and RAC1";"MET activates PTPN11";"Signal regulatory protein family interactions";"Insulin receptor signalling cascade";"PI-3K cascade:FGFR2";"Costimulation by the CD28 family";"GRB2 events in EGFR signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR Transactivation by Gastrin";"EGFR downregulation";"Role of LAT2/NTAL/LAB on calcium mobilization";"Signaling by FGFR2 in disease";"SHC-mediated cascade:FGFR2";"Negative regulation of FGFR3 signaling";"MET receptor recycling";"Erythropoietin activates RAS";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"STAT5 Activation";"Signal attenuation";"Constitutive Signaling by EGFRvIII";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"GRB2 events in ERBB2 signaling";"PIP3 activates AKT signaling";"CD28 dependent Vav1 pathway";"PI-3K cascade:FGFR4";"NCAM signaling for neurite out-growth";"Activated NTRK3 signals through RAS";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Regulation of actin dynamics for phagocytic cup formation";"SHC-mediated cascade:FGFR3";"RET signaling";"SHC-mediated cascade:FGFR1";"Signaling by FGFR4 in disease";"MET activates PI3K/AKT signaling";"Negative regulation of FGFR1 signaling";"SHC-related events triggered by IGF1R";"PI3K events in ERBB2 signaling";"FRS-mediated FGFR2 signaling" XP_037300475.1 7 MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469 "Justicidin B biosynthesis";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis" XP_030021801.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037299519.1 3 Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646 "Defective ACY1 causes encephalopathy";"Arginine biosynthesis";"Aflatoxin activation and detoxification" XP_030033502.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_030037622.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037296321.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_030034180.2 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_030023728.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265 "Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes" XP_037295378.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030024539.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037293550.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_037297342.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_030028644.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_030031217.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037298117.1 2 Reactome: R-HSA-6811436;Reactome: R-HSA-8876198 "COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_030024655.2 5 Reactome: R-HSA-381038;MetaCyc: PWY-7511;Reactome: R-HSA-901032;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346 "XBP1(S) activates chaperone genes";"Protein ubiquitination";"ER Quality Control Compartment (ERQC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis" XP_037295067.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_037301947.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_030024678.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_037301578.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037300725.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_037295642.1 3 KEGG: 00860+2.5.1.141;MetaCyc: PWY-7856;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"Heme a biosynthesis";"Heme biosynthesis" XP_030037098.1 3 MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23 "Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism" XP_037299345.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037301695.1 16 Reactome: R-HSA-176407;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-174048;Reactome: R-HSA-141430 "Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"Inactivation of APC/C via direct inhibition of the APC/C complex" XP_037301987.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_030035116.2 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_030021063.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037303495.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_037298085.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037300933.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_030031331.1 12 Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-141444 "RHO GTPases Activate Formins";"HCMV Early Events";"Aggrephagy";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_030021550.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030023241.1 4 Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_030021375.1 2 Reactome: R-HSA-1912399;KEGG: 00514+2.4.1.221 "Pre-NOTCH Processing in the Endoplasmic Reticulum";"Other types of O-glycan biosynthesis" XP_030037827.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030028759.2 15 MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-7218;KEGG: 00230+2.7.1.40;MetaCyc: PWY-5723;MetaCyc: PWY-6886;KEGG: 00620+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-6142;MetaCyc: PWY-7003 "Glycolysis IV (plant cytosol)";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Purine metabolism";"Rubisco shunt";"1-butanol autotrophic biosynthesis (engineered)";"Pyruvate metabolism";"Entner-Doudoroff pathway I";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol" XP_030041181.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_030019867.2 6 Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1855183;Reactome: R-HSA-1660516;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.66 "Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the early endosome membrane";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system" XP_037300461.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037295853.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_030032734.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_030032567.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_030040993.2 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_037295617.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030034167.2 6 Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649 "L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation" XP_030028376.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037294111.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_030023677.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" XP_030024271.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_030035625.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_030036540.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_030019737.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" XP_037296578.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_030026873.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_037303037.1 24 Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257 "The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Kinesins";"Aggrephagy";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion" XP_030036158.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_030040711.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_030028419.1 3 Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis" XP_030024132.2 1 Reactome: R-HSA-2468052 "Establishment of Sister Chromatid Cohesion" XP_037295515.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_030040533.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_030028474.1 2 KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201 "Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_037302533.1 1 Reactome: R-HSA-379716 "Cytosolic tRNA aminoacylation" XP_037302356.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_037300125.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_030031315.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_030028371.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037299300.1 7 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway" XP_030028392.1 17 Reactome: R-HSA-2173796;Reactome: R-HSA-8953750;Reactome: R-HSA-1362300;Reactome: R-HSA-2559580;Reactome: R-HSA-2559585;Reactome: R-HSA-113501;Reactome: R-HSA-6804114;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-139915;Reactome: R-HSA-9616222;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-69231;Reactome: R-HSA-1912408;Reactome: R-HSA-111448;Reactome: R-HSA-1538133 "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcriptional Regulation by E2F6";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Oxidative Stress Induced Senescence";"Oncogene Induced Senescence";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Activation of PUMA and translocation to mitochondria";"Transcriptional regulation of granulopoiesis";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Cyclin D associated events in G1";"Pre-NOTCH Transcription and Translation";"Activation of NOXA and translocation to mitochondria";"G0 and Early G1" XP_030022431.1 1 Reactome: R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" XP_030024300.2 7 MetaCyc: PWY-7791;MetaCyc: PWY-5697;MetaCyc: PWY-7790;KEGG: 00240+3.5.2.3;KEGG: 00230+3.5.2.5;MetaCyc: PWY-5698;MetaCyc: PWY-5686 "UMP biosynthesis III";"Allantoin degradation to ureidoglycolate I (urea producing)";"UMP biosynthesis II";"Pyrimidine metabolism";"Purine metabolism";"Allantoin degradation to ureidoglycolate II (ammonia producing)";"UMP biosynthesis I" XP_037294371.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037292528.1 1 Reactome: R-HSA-110357 "Displacement of DNA glycosylase by APEX1" XP_037301877.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030028382.1 4 Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_030041000.2 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_030028384.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_030022642.1 14 MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-6453;MetaCyc: PWY-5981;MetaCyc: PWY-7782;Reactome: R-HSA-1483166 "Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"Synthesis of PA" XP_030037238.1 1 Reactome: R-HSA-419771 "Opsins" XP_037297593.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706 "Eukaryotic Translation Termination";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037298812.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_030033912.2 8 KEGG: 00564+3.1.3.27;MetaCyc: PWY-5668;MetaCyc: PWY-5269;Reactome: R-HSA-1483148;KEGG: 04660+3.1.3.16;MetaCyc: PWY-7817;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "Glycerophospholipid metabolism";"Cardiolipin biosynthesis I";"Cardiolipin biosynthesis II";"Synthesis of PG";"T cell receptor signaling pathway";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_030034884.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_030023598.2 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_030027056.2 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037293652.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_030028312.2 5 KEGG: 00640+1.2.4.4;MetaCyc: PWY-5046;Reactome: R-HSA-70895;KEGG: 00280+1.2.4.4;Reactome: R-HSA-389661 "Propanoate metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation";"Glyoxylate metabolism and glycine degradation" XP_037296150.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030030658.1 2 Reactome: R-HSA-5683371;Reactome: R-HSA-1369007 "Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters" XP_030027470.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_030032182.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_037300859.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_037297208.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_037295333.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037294193.1 3 Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596 "Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I" XP_030028381.1 4 KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219 "Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_030031075.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_030033500.2 3 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.4;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism" XP_037299202.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_030020500.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030039307.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037296143.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037299720.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_030019706.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_037299135.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_030028850.1 17 MetaCyc: PWY-6722;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5966-1;KEGG: 00061+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-6679;Reactome: R-HSA-163765;MetaCyc: PWY-4381;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5744;Reactome: R-HSA-196780;MetaCyc: PWY-5743;Reactome: R-HSA-200425;KEGG: 00620+6.4.1.2;Reactome: R-HSA-2426168;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5789 "Candicidin biosynthesis";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Jadomycin biosynthesis";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (bacteria and plants)";"Propanoate metabolism";"Glyoxylate assimilation";"Biotin transport and metabolism";"3-hydroxypropanoate cycle";"Carnitine metabolism";"Pyruvate metabolism";"Activation of gene expression by SREBF (SREBP)";"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate/4-hydroxybutanate cycle" XP_030025251.2 2 Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_030036933.2 4 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling" XP_030041035.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_037302898.1 7 MetaCyc: PWY-8052;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039 "2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule" XP_030023138.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037296969.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_037294406.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862 "Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_037295392.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_037296507.1 9 Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-400253 "RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock" XP_037301811.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_037292425.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_030038615.2 4 Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-381771 "Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" XP_030040984.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_030037828.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_030040677.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_030034421.1 32 Reactome: R-HSA-167161;Reactome: R-HSA-167287;Reactome: R-HSA-75953;Reactome: R-HSA-72165;Reactome: R-HSA-76042;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-6803529;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-168325;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-72203;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-8851708;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-167243;Reactome: R-HSA-9018519 "HIV Transcription Initiation";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Viral Messenger RNA Synthesis";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated HIV elongation arrest and recovery";"Estrogen-dependent gene expression" XP_037298659.1 20 KEGG: 00592+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7726;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7007;MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7338;MetaCyc: PWY-7854;MetaCyc: PWY-7858;MetaCyc: PWY-7288;MetaCyc: PWY-7291;MetaCyc: PWY-735;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7574 "alpha-Linolenic acid metabolism";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Methyl ketone biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"6-gingerol analog biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"beta-Alanine metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoyl-coa degradation II" XP_030032060.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012 "SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_030032287.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118 "SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors" XP_030021743.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_030035635.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_030036311.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_037299980.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_030029521.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037296727.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_030027124.2 8 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Activation of RAC1";"Human immunodeficiency virus 1 infection" XP_037298568.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_030021582.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_037300413.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_030024753.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037294992.1 14 MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-5972 "Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)" XP_037298407.1 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_030025904.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_030025920.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037299217.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_030024361.2 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_037295361.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_030031955.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_030021955.1 7 Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-1834949 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA" XP_030021380.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553 "Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs" XP_037296309.1 56 Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-983168;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-382556;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-8939902;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-1234176;Reactome: R-HSA-8939236 "Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Antigen processing: Ubiquitination & Proteasome degradation";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Degradation of DVL";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"Hedgehog 'on' state";"ABC-family proteins mediated transport";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX2 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_037297198.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518 "Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2" XP_030023852.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_037301790.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_037294830.1 2 Reactome: R-HSA-442660;Reactome: R-HSA-352230 "Na+/Cl- dependent neurotransmitter transporters";"Amino acid transport across the plasma membrane" XP_037295547.1 27 Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107 "Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)" XP_030021064.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030021880.1 4 KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3 "Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_030030976.2 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_037298366.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_030040497.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030020901.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_030022878.2 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037297751.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_037299241.1 7 Reactome: R-HSA-8949613;Reactome: R-HSA-2151201;MetaCyc: PWY-7980;Reactome: R-HSA-1268020;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-163210 "Cristae formation";"Transcriptional activation of mitochondrial biogenesis";"ATP biosynthesis";"Mitochondrial protein import";"Photosynthesis";"Oxidative phosphorylation";"Formation of ATP by chemiosmotic coupling" XP_030023007.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037292429.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_037293294.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037302066.1 5 KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;MetaCyc: PWY-6749 "Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"CMP-legionaminate biosynthesis I" XP_037300790.1 7 Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-373753;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-264870;Reactome: R-HSA-6798695 "NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"Nephrin family interactions";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation" XP_030040624.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_030040045.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030030180.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_030033196.2 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037293998.1 22 Reactome: R-HSA-5358747;Reactome: R-HSA-5358752;Reactome: R-HSA-9648025;Reactome: R-HSA-432142;Reactome: R-HSA-68877;Reactome: R-HSA-5358749;Reactome: R-HSA-5673000;Reactome: R-HSA-2467813;Reactome: R-HSA-196299;Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-5467348;Reactome: R-HSA-141444;Reactome: R-HSA-6811558;Reactome: R-HSA-4641262;Reactome: R-HSA-389513;Reactome: R-HSA-5675221;Reactome: R-HSA-5663220;Reactome: R-HSA-5339716;Reactome: R-HSA-5467340;Reactome: R-HSA-2500257;Reactome: R-HSA-5358751 "S33 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"Platelet sensitization by LDL";"Mitotic Prometaphase";"S37 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Separation of Sister Chromatids";"Beta-catenin phosphorylation cascade";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"CTLA4 inhibitory signaling";"Negative regulation of MAPK pathway";"RHO GTPases Activate Formins";"Misspliced GSK3beta mutants stabilize beta-catenin";"AXIN missense mutants destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion";"S45 mutants of beta-catenin aren't phosphorylated" XP_037297190.1 1 Reactome: R-HSA-72731 "Recycling of eIF2:GDP" XP_030026093.1 7 Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2660826 "Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant" XP_030021491.1 3 MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106 "Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)" XP_037295077.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_037296551.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_030037146.2 7 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_037302223.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037297158.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_037293732.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_030034802.2 3 Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5621575 "NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"CD209 (DC-SIGN) signaling" XP_037299215.1 6 Reactome: R-HSA-416993;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-204005;Reactome: R-HSA-6811438 "Trafficking of GluR2-containing AMPA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport";"Intra-Golgi traffic" XP_030021356.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030026779.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_037303106.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037292567.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037292307.1 30 Reactome: R-HSA-167161;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-73772;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-76042;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-5696395;Reactome: R-HSA-73863;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-2564830;Reactome: R-HSA-75955;Reactome: R-HSA-167160;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-5696400;Reactome: R-HSA-73776 "HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Termination";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Cytosolic iron-sulfur cluster assembly";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"Dual Incision in GG-NER";"RNA Polymerase II Promoter Escape" XP_037296056.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_030040455.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156902 "Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Peptide chain elongation" XP_030040939.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_030031224.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" XP_037293650.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_030023965.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_030032283.1 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_030032167.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037293393.1 7 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection" XP_037294779.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_037297478.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_030032995.1 12 Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167243 "HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery" XP_030024454.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_037293426.1 7 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection" XP_030020636.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_030027794.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030035891.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_030024796.2 3 Reactome: R-HSA-2980766;Reactome: R-HSA-2995383;Reactome: R-HSA-4419969 "Nuclear Envelope Breakdown";"Initiation of Nuclear Envelope Reformation";"Depolymerisation of the Nuclear Lamina" XP_030023206.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_030039493.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037296163.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037295162.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_037298977.1 3 MetaCyc: PWY-7799;Reactome: R-HSA-2514859;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Inactivation, recovery and regulation of the phototransduction cascade";"Ac/N-end rule pathway" XP_030019731.1 2 Reactome: R-HSA-8854214;Reactome: R-HSA-977225 "TBC/RABGAPs";"Amyloid fiber formation" XP_037293503.1 7 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_030030997.1 29 Reactome: R-HSA-5693607;Reactome: R-HSA-5696395;Reactome: R-HSA-5693616;Reactome: R-HSA-3108214;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-3371453;Reactome: R-HSA-5655862;Reactome: R-HSA-6804756;Reactome: R-HSA-5651801;Reactome: R-HSA-68962;Reactome: R-HSA-5696400;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-174437;Reactome: R-HSA-3371511;Reactome: R-HSA-6783310;Reactome: R-HSA-69166;Reactome: R-HSA-5696397;Reactome: R-HSA-5358606;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5358565;Reactome: R-HSA-912446;Reactome: R-HSA-176187;Reactome: R-HSA-110314;Reactome: R-HSA-6782210 "Processing of DNA double-strand break ends";"Formation of Incision Complex in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"SUMOylation of DNA damage response and repair proteins";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Regulation of HSF1-mediated heat shock response";"Translesion synthesis by POLK";"Regulation of TP53 Activity through Phosphorylation";"PCNA-Dependent Long Patch Base Excision Repair";"Activation of the pre-replicative complex";"Dual Incision in GG-NER";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Removal of the Flap Intermediate from the C-strand";"HSF1 activation";"Fanconi Anemia Pathway";"Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Meiotic recombination";"Activation of ATR in response to replication stress";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_030027263.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_030033111.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037292252.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_030023595.2 1 Reactome: R-HSA-75153 "Apoptotic execution phase" XP_030030757.2 1 Reactome: R-HSA-8951664 "Neddylation" XP_030021842.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_037297442.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" XP_030031524.2 4 Reactome: R-HSA-167160;MetaCyc: PWY-7375;Reactome: R-HSA-77075;Reactome: R-HSA-72086 "RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping" XP_037302781.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037294965.1 7 Reactome: R-HSA-5083628;Reactome: R-HSA-3000171;Reactome: R-HSA-5083629;Reactome: R-HSA-9010553;Reactome: R-HSA-5083633;Reactome: R-HSA-5173105;Reactome: R-HSA-3000178 "Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Regulation of expression of SLITs and ROBOs";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation";"ECM proteoglycans" XP_030028158.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030035610.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037301340.1 10 MetaCyc: PWY-6453;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.15;MetaCyc: PWY-5667 "Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I" XP_030041092.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_030029020.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_037297176.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037294758.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_037300872.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_037292347.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037296164.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030041045.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_030029602.1 11 MetaCyc: PWY-6859;MetaCyc: PWY-6383;MetaCyc: PWY-7391;MetaCyc: PWY-7524;MetaCyc: PWY-5123;MetaCyc: PWY-922;MetaCyc: PWY-7102;KEGG: 00900+5.3.3.2;MetaCyc: PWY-7560;MetaCyc: PWY-6174;Reactome: R-HSA-191273 "All-trans-farnesol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Trans, trans-farnesyl diphosphate biosynthesis";"Mevalonate pathway I";"Bisabolene biosynthesis (engineered)";"Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II";"Mevalonate pathway II (archaea)";"Cholesterol biosynthesis" XP_030026847.2 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_037299985.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_030023541.2 6 KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817 "Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_030035666.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037296028.1 29 Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-73772;Reactome: R-HSA-6782135;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-76042;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-5696395;Reactome: R-HSA-73863;Reactome: R-HSA-113418;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167160;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-5696400;Reactome: R-HSA-73776 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Promoter Escape";"Dual incision in TC-NER";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Termination";"Formation of the Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Dual Incision in GG-NER";"RNA Polymerase II Promoter Escape" XP_030039468.1 2 KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111 "Fatty acid degradation";"Mitochondrial L-carnitine shuttle" XP_037292679.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_037299458.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_030040320.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_037293193.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-1834949 "Neutrophil degranulation";"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA" XP_037297091.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_037298579.1 17 Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-6790901;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"rRNA modification in the nucleus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination" XP_037298222.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037294167.1 13 MetaCyc: PWY-2201;MetaCyc: PWY-2161;KEGG: 00670+6.3.4.3;MetaCyc: PWY-1722;MetaCyc: PWY-5030;MetaCyc: PWY-5497;KEGG: 00670+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00720+6.3.4.3;MetaCyc: PWY-6613;MetaCyc: PWY-3841;MetaCyc: PWY-7909 "Folate transformations I";"Folate polyglutamylation";"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"L-histidine degradation III";"Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations II (plants)";"Formaldehyde oxidation VII (THF pathway)" XP_030022353.2 7 MetaCyc: PWY-6614;Reactome: R-HSA-1474151;Reactome: R-HSA-69205;KEGG: 00670+1.5.1.3;Reactome: R-HSA-196757;MetaCyc: PWY-3841;KEGG: 00790+1.5.1.3 "Tetrahydrofolate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"G1/S-Specific Transcription";"One carbon pool by folate";"Metabolism of folate and pterines";"Folate transformations II (plants)";"Folate biosynthesis" XP_030024685.1 4 Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-8953750;Reactome: R-HSA-1362277 "Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional Regulation by E2F6";"Transcription of E2F targets under negative control by DREAM complex" XP_030035453.2 7 Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-6798695;Reactome: R-HSA-389960;Reactome: R-HSA-390450 "Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC" XP_037300779.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_030022030.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823 "Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation" XP_037298367.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037302126.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030032226.2 3 Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191 "Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC" XP_037302394.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-77595 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs" XP_030040976.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_030035736.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_030032315.2 3 KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282;Reactome: R-HSA-2024096 "Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B";"HS-GAG degradation" XP_037302536.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_037303024.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_030023286.2 2 Reactome: R-HSA-203927;Reactome: R-HSA-8986944 "MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2" XP_030023773.2 3 Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6787450 "rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion" XP_037300286.1 22 MetaCyc: PWY-7049;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-5353;MetaCyc: PWY-8041;MetaCyc: PWY-7606;MetaCyc: PWY-7725;MetaCyc: PWY-7592;MetaCyc: PWY-7728;MetaCyc: PWY-6958;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7726;MetaCyc: PWY-7727;MetaCyc: PWY-7724;MetaCyc: PWY-6598;Reactome: R-HSA-75876;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7053;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7601 "Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_037292906.1 14 Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-1632852;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-5620924;Reactome: R-HSA-141444;Reactome: R-HSA-3371497 "COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Macroautophagy";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HCMV Early Events";"Aggrephagy";"Intraflagellar transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_030028357.2 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_037294841.1 16 Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823 "Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation" XP_037300122.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_030028427.2 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_030020583.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_030023223.2 3 KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317 "Glycolysis / Gluconeogenesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)" XP_037303581.1 27 Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-6784531 "Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus" XP_037295534.1 11 Reactome: R-HSA-210455;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6549;KEGG: 00250+6.3.1.2;KEGG: 00910+6.3.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-6964;MetaCyc: PWY-5675;MetaCyc: PWY-381;MetaCyc: PWY-6963;KEGG: 00630+6.3.1.2 "Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Arginine biosynthesis";"L-glutamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Glutamate and glutamine metabolism";"Ammonia assimilation cycle II";"Nitrate reduction V (assimilatory)";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle I";"Glyoxylate and dicarboxylate metabolism" XP_037297838.1 1 Reactome: R-HSA-1483101 "Synthesis of PS" XP_037295872.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_030032915.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1" XP_030036401.1 1 Reactome: R-HSA-9018519 "Estrogen-dependent gene expression" XP_030021329.2 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" XP_037295614.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_037300925.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" XP_030028795.1 10 Reactome: R-HSA-9636383;Reactome: R-HSA-432720;Reactome: R-HSA-9635644;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-917729;Reactome: R-HSA-5689880;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8875360 "Prevention of phagosomal-lysosomal fusion";"Lysosome Vesicle Biogenesis";"Inhibition of membrane repair";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Ub-specific processing proteases";"Negative regulation of MET activity";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell" XP_030031297.2 2 Reactome: R-HSA-2151201;Reactome: R-HSA-8964539 "Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism" XP_037294051.1 10 Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-9018519;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-76042 "Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Estrogen-dependent gene expression";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_037300132.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037294464.1 13 Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6802946;Reactome: R-HSA-6802948;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6802952;Reactome: R-HSA-5674135 "Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Signaling by moderate kinase activity BRAF mutants";"Signaling by high-kinase activity BRAF mutants";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation" XP_030041094.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_037301474.1 15 Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-8943723;Reactome: R-HSA-2559580;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569 "Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Oncogene Induced Senescence";"Regulation of PTEN mRNA translation";"Oxidative Stress Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_037301761.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_030030583.2 10 MetaCyc: PWY-7328;Reactome: R-HSA-70370;Reactome: R-HSA-5609977;KEGG: 00052+5.1.3.2;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6317;MetaCyc: PWY-7344;MetaCyc: PWY-6397;MetaCyc: PWY-3821;MetaCyc: PWY-6527 "Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose catabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"UDP-alpha-D-galactose biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose detoxification";"Stachyose degradation" XP_030026911.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_030032688.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_030036181.2 7 Reactome: R-HSA-71403;Reactome: R-HSA-389661;KEGG: 00380+2.3.1.61;Reactome: R-HSA-71064;KEGG: 00310+2.3.1.61;KEGG: 00020+2.3.1.61;MetaCyc: PWY-5084 "Citric acid cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Lysine catabolism";"Lysine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_037292206.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037300754.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037294711.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037292637.1 6 Reactome: R-HSA-6804759;Reactome: R-HSA-6803205;Reactome: R-HSA-139915;Reactome: R-HSA-6803211;Reactome: R-HSA-6803204;Reactome: R-HSA-6803207 "Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Caspase Activators and Caspases" XP_037300814.1 7 MetaCyc: PWY-6121;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6122;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6277;Reactome: R-HSA-73817;MetaCyc: PWY-7282 "5-aminoimidazole ribonucleotide biosynthesis I";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis" XP_030027388.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_030033551.2 3 Reactome: R-HSA-4724325;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.265 "Defective ALG8 causes ALG8-CDG (CDG-1h)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis" XP_030028414.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_037293864.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_030020733.2 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_030021680.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_030023857.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_030022504.1 4 MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603 "Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis";"HATs acetylate histones";"UCH proteinases" XP_037300917.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037292946.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518 "Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2" XP_030035661.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_030020551.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030028104.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434 "MHC class II antigen presentation";"Kinesins";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037294254.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037300749.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_037300664.1 10 Reactome: R-HSA-6798695;Reactome: R-HSA-2453864;Reactome: R-HSA-3000171;MetaCyc: PWY-7849;Reactome: R-HSA-977225;KEGG: 00230+3.5.2.17;Reactome: R-HSA-2453902;MetaCyc: PWY-5691;MetaCyc: PWY-7394;Reactome: R-HSA-975634 "Neutrophil degranulation";"Retinoid cycle disease events";"Non-integrin membrane-ECM interactions";"Urate conversion to allantoin III";"Amyloid fiber formation";"Purine metabolism";"The canonical retinoid cycle in rods (twilight vision)";"Urate conversion to allantoin I";"Urate conversion to allantoin II";"Retinoid metabolism and transport" XP_037300271.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_030031537.2 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_030027542.1 179 Reactome: R-HSA-5689877;Reactome: R-HSA-8866654;Reactome: R-HSA-975163;Reactome: R-HSA-174178;Reactome: R-HSA-2691232;Reactome: R-HSA-6782135;Reactome: R-HSA-5693607;Reactome: R-HSA-72764;Reactome: R-HSA-2122948;Reactome: R-HSA-937042;Reactome: R-HSA-5362768;Reactome: R-HSA-2559580;Reactome: R-HSA-8948751;Reactome: R-HSA-5685942;Reactome: R-HSA-5684264;Reactome: R-HSA-8948747;Reactome: R-HSA-936964;Reactome: R-HSA-9636383;Reactome: R-HSA-110312;Reactome: R-HSA-2672351;Reactome: R-HSA-5696400;Reactome: R-HSA-5607764;Reactome: R-HSA-2979096;Reactome: R-HSA-1236382;Reactome: R-HSA-5610783;Reactome: R-HSA-9013507;Reactome: R-HSA-5654726;Reactome: R-HSA-9645460;Reactome: R-HSA-9604323;Reactome: R-HSA-5656169;Reactome: R-HSA-2559585;Reactome: R-HSA-201681;Reactome: R-HSA-4641263;Reactome: R-HSA-2173788;Reactome: R-HSA-4641257;Reactome: R-HSA-68949;Reactome: R-HSA-72706;Reactome: R-HSA-209560;Reactome: R-HSA-6782210;Reactome: R-HSA-975144;Reactome: R-HSA-180534;Reactome: R-HSA-5696397;Reactome: R-HSA-5678895;Reactome: R-HSA-2173796;Reactome: R-HSA-5676590;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-187577;Reactome: R-HSA-9033241;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-9637628;Reactome: R-HSA-8856828;Reactome: R-HSA-445989;Reactome: R-HSA-6781823;Reactome: R-HSA-205043;Reactome: R-HSA-195253;Reactome: R-HSA-5357905;Reactome: R-HSA-75815;Reactome: R-HSA-9613829;Reactome: R-HSA-977225;Reactome: R-HSA-9646399;Reactome: R-HSA-110320;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-6783310;Reactome: R-HSA-5205685;Reactome: R-HSA-1169091;Reactome: R-HSA-8856825;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-5696394;Reactome: R-HSA-5357956;Reactome: R-HSA-5675221;Reactome: R-HSA-69541;Reactome: R-HSA-9014325;Reactome: R-HSA-3134975;Reactome: R-HSA-5696395;Reactome: R-HSA-8941858;Reactome: R-HSA-180585;Reactome: R-HSA-6807004;Reactome: R-HSA-5689603;Reactome: R-HSA-5689901;Reactome: R-HSA-8939902;Reactome: R-HSA-2173791;Reactome: R-HSA-450408;Reactome: R-HSA-5654733;Reactome: R-HSA-8939236;Reactome: R-HSA-8863795;Reactome: R-HSA-156827;Reactome: R-HSA-5655862;Reactome: R-HSA-5693565;Reactome: R-HSA-2644606;Reactome: R-HSA-174184;Reactome: R-HSA-8866652;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-936440;Reactome: R-HSA-5675482;Reactome: R-HSA-2894862;Reactome: R-HSA-5654732;Reactome: R-HSA-1169408;Reactome: R-HSA-110314;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-68827;Reactome: R-HSA-2408557;Reactome: R-HSA-8876493;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-168638;Reactome: R-HSA-9615710;Reactome: R-HSA-975110;Reactome: R-HSA-174490;Reactome: R-HSA-6804757;Reactome: R-HSA-69017;Reactome: R-HSA-6804760;Reactome: R-HSA-3785653;Reactome: R-HSA-5687128;Reactome: R-HSA-8849469;Reactome: R-HSA-901032;Reactome: R-HSA-9010553;Reactome: R-HSA-917937;Reactome: R-HSA-69601;Reactome: R-HSA-1253288;Reactome: R-HSA-450321;Reactome: R-HSA-1234176;Reactome: R-HSA-5656121;Reactome: R-HSA-9633012;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-175474;Reactome: R-HSA-9013973;Reactome: R-HSA-69231;Reactome: R-HSA-202424;Reactome: R-HSA-912631;Reactome: R-HSA-5358346;Reactome: R-HSA-1295596;Reactome: R-HSA-5610780;Reactome: R-HSA-72689;Reactome: R-HSA-162588;Reactome: R-HSA-975956;Reactome: R-HSA-168927;Reactome: R-HSA-168928;Reactome: R-HSA-4641258;Reactome: R-HSA-532668;Reactome: R-HSA-3322077;Reactome: R-HSA-400253;Reactome: R-HSA-937072;Reactome: R-HSA-2565942;Reactome: R-HSA-211733;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-382556;Reactome: R-HSA-6804756;Reactome: R-HSA-5689896;Reactome: R-HSA-349425;Reactome: R-HSA-937039;Reactome: R-HSA-6781827;Reactome: R-HSA-2173795;Reactome: R-HSA-937041;Reactome: R-HSA-5668541;Reactome: R-HSA-6791226;Reactome: R-HSA-209543;Reactome: R-HSA-174154;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-975957;Reactome: R-HSA-5654727;Reactome: R-HSA-450302;Reactome: R-HSA-1358803;Reactome: R-HSA-174048;Reactome: R-HSA-917729;Reactome: R-HSA-156902 "Josephin domain DUBs";"E3 ubiquitin ligases ubiquitinate target proteins";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Dual incision in TC-NER";"Processing of DNA double-strand break ends";"Eukaryotic Translation Termination";"Activated NOTCH1 Transmits Signal to the Nucleus";"IRAK2 mediated activation of TAK1 complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Oxidative Stress Induced Senescence";"Regulation of PTEN stability and activity";"HDR through Homologous Recombination (HRR)";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of PTEN localization";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Prevention of phagosomal-lysosomal fusion";"Translesion synthesis by REV1";"Stimuli-sensing channels";"Dual Incision in GG-NER";"CLEC7A (Dectin-1) signaling";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Degradation of GLI2 by the proteasome";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Negative regulation of FGFR1 signaling";"Alpha-protein kinase 1 signaling pathway";"Negative regulation of NOTCH4 signaling";"Termination of translesion DNA synthesis";"Oncogene Induced Senescence";"TCF dependent signaling in response to WNT";"Regulation of FZD by ubiquitination";"Downregulation of TGF-beta receptor signaling";"Degradation of AXIN";"Orc1 removal from chromatin";"GTP hydrolysis and joining of the 60S ribosomal subunit";"NF-kB is activated and signals survival";"Gap-filling DNA repair synthesis and ligation in TC-NER";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Vpu mediated degradation of CD4";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Defective CFTR causes cystic fibrosis";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NIK-->noncanonical NF-kB signaling";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"SCF(Skp2)-mediated degradation of p27/p21";"Peroxisomal protein import";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Modulation by Mtb of host immune system";"Clathrin-mediated endocytosis";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Formation of TC-NER Pre-Incision Complex";"NRIF signals cell death from the nucleus";"Degradation of beta-catenin by the destruction complex";"Regulation of TNFR1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Chaperone Mediated Autophagy";"Amyloid fiber formation";"Aggrephagy";"Translesion Synthesis by POLH";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Fanconi Anemia Pathway";"Pink/Parkin Mediated Mitophagy";"Activation of NF-kappaB in B cells";"Cargo recognition for clathrin-mediated endocytosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"DNA Damage Recognition in GG-NER";"TNFR1-induced NFkappaB signaling pathway";"Negative regulation of MAPK pathway";"Stabilization of p53";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Regulation of innate immune responses to cytosolic DNA";"Formation of Incision Complex in GG-NER";"Regulation of RUNX3 expression and activity";"Vif-mediated degradation of APOBEC3G";"Negative regulation of MET activity";"UCH proteinases";"Metalloprotease DUBs";"Regulation of RUNX2 expression and activity";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Negative regulation of FGFR4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downregulation of ERBB2 signaling";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translesion synthesis by POLK";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Negative regulators of DDX58/IFIH1 signaling";"Regulation of necroptotic cell death";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Negative regulation of FGFR3 signaling";"ISG15 antiviral mechanism";"Recognition of DNA damage by PCNA-containing replication complex";"Separation of Sister Chromatids";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"CDT1 association with the CDC6:ORC:origin complex";"Selenocysteine synthesis";"InlA-mediated entry of Listeria monocytogenes into host cells";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"NOD1/2 Signaling Pathway";"Late endosomal microautophagy";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Membrane binding and targetting of GAG proteins";"Regulation of TP53 Degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of TP53 Activity through Methylation";"Myoclonic epilepsy of Lafora";"MAPK6/MAPK4 signaling";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"ER Quality Control Compartment (ERQC)";"Regulation of expression of SLITs and ROBOs";"Iron uptake and transport";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downregulation of ERBB4 signaling";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Translesion synthesis by POLI";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Assembly Of The HIV Virion";"TICAM1-dependent activation of IRF3/IRF7";"Cyclin D associated events in G1";"Downstream TCR signaling";"Regulation of signaling by CBL";"Hedgehog ligand biogenesis";"Spry regulation of FGF signaling";"Degradation of GLI1 by the proteasome";"Formation of a pool of free 40S subunits";"Budding and maturation of HIV virion";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"TICAM1, RIP1-mediated IKK complex recruitment";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Degradation of DVL";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Glycogen synthesis";"Circadian Clock";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Regulation of PLK1 Activity at G2/M Transition";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"ABC-family proteins mediated transport";"Regulation of TP53 Activity through Phosphorylation";"Ovarian tumor domain proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"IRAK1 recruits IKK complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"IKK complex recruitment mediated by RIP1";"TNFR2 non-canonical NF-kB pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"p75NTR recruits signalling complexes";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Negative regulation of FGFR2 signaling";"activated TAK1 mediates p38 MAPK activation";"Downregulation of ERBB2:ERBB3 signaling";"APC/C:Cdc20 mediated degradation of Cyclin B";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Peptide chain elongation" XP_030030432.1 16 Reactome: R-HSA-190873;Reactome: R-HSA-8964038;Reactome: R-HSA-5099900;Reactome: R-HSA-8856828;Reactome: R-HSA-8866427;Reactome: R-HSA-2132295;Reactome: R-HSA-3928665;Reactome: R-HSA-196025;Reactome: R-HSA-177504;Reactome: R-HSA-164939;Reactome: R-HSA-8856825;Reactome: R-HSA-416993;Reactome: R-HSA-182218;Reactome: R-HSA-5140745;Reactome: R-HSA-167590;Reactome: R-HSA-437239 "Gap junction degradation";"LDL clearance";"WNT5A-dependent internalization of FZD4";"Clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"MHC class II antigen presentation";"EPH-ephrin mediated repulsion of cells";"Formation of annular gap junctions";"Retrograde neurotrophin signalling";"Nef mediated downregulation of CD28 cell surface expression";"Cargo recognition for clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors";"Nef Mediated CD8 Down-regulation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Nef Mediated CD4 Down-regulation";"Recycling pathway of L1" XP_030031713.2 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_030024412.1 2 Reactome: R-HSA-5632681;Reactome: R-HSA-5635838 "Ligand-receptor interactions";"Activation of SMO" XP_037298223.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_030026868.2 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_037298912.1 3 KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis" XP_037299308.1 5 Reactome: R-HSA-5579026;Reactome: R-HSA-1362409;Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-196108 "Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis" XP_037302876.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_030037430.2 1 Reactome: R-HSA-211981 "Xenobiotics" XP_037293402.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_030021659.1 8 KEGG: 00350+1.14.16.2;KEGG: 00790+1.14.16.2;MetaCyc: PWY-5394;MetaCyc: PWY-5049;MetaCyc: PWY-6133;KEGG: 00950+1.14.16.2;MetaCyc: PWY-3581;Reactome: R-HSA-209905 "Tyrosine metabolism";"Folate biosynthesis";"Betalamic acid biosynthesis";"Rosmarinic acid biosynthesis II";"(S)-reticuline biosynthesis II";"Isoquinoline alkaloid biosynthesis";"(S)-reticuline biosynthesis I";"Catecholamine biosynthesis" XP_037292262.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway" XP_030038559.2 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_037300292.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_030025201.1 3 Reactome: R-HSA-174403;MetaCyc: PWY-4041;KEGG: 00480+4.3.2.9 "Glutathione synthesis and recycling";"Gamma-glutamyl cycle";"Glutathione metabolism" XP_037303483.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_030031117.1 9 KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"tRNA modification in the nucleus and cytosol";"Human immunodeficiency virus 1 infection" XP_030020135.2 3 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.5;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism" XP_037301253.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_030029656.2 4 Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554 "Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_030029632.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030032348.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_030028113.2 3 MetaCyc: PWY-7221;Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions";"Purine metabolism" XP_030021778.2 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_037300278.1 5 KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922 "Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_030040311.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_037296162.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030026987.1 2 Reactome: R-HSA-6803205;Reactome: R-HSA-8873719 "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation" XP_030026357.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553 "Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs" XP_030031518.1 57 Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-180534;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553 "Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Vpu mediated degradation of CD4";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Regulation of expression of SLITs and ROBOs" XP_037296995.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_037303596.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_037301643.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664 "Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation" XP_030030896.1 33 MetaCyc: PWY-7798;MetaCyc: PWY-6342;MetaCyc: PWY-1801;MetaCyc: PWY-5057;KEGG: 00982+1.1.1.1;MetaCyc: PWY-6587;KEGG: 00071+1.1.1.1;MetaCyc: PWY-7396;MetaCyc: PWY-5079;MetaCyc: PWY-6802;Reactome: R-HSA-71384;MetaCyc: PWY-7118;MetaCyc: PWY-6313;MetaCyc: PWY-3162;MetaCyc: PWY-7111;MetaCyc: PWY-5076;KEGG: 00625+1.1.1.1;MetaCyc: PWY-5751;KEGG: 00260+1.1.1.1;MetaCyc: PWY-7013;MetaCyc: PWY-6333;KEGG: 00350+1.1.1.1;KEGG: 00626+1.1.1.1;MetaCyc: PWY-5486;KEGG: 00680+1.1.1.284;MetaCyc: PWY-6871;MetaCyc: PWY-5078;KEGG: 00980+1.1.1.1;MetaCyc: PWY-5480;KEGG: 00010+1.1.1.1;KEGG: 00830+1.1.1.1;MetaCyc: PWY-5082;KEGG: 00592+1.1.1.1 "Protein S-nitrosylation and denitrosylation";"Noradrenaline and adrenaline degradation";"Formaldehyde oxidation II (glutathione-dependent)";"L-valine degradation II";"Drug metabolism - cytochrome P450";"Pyruvate fermentation to ethanol III";"Fatty acid degradation";"Butanol and isobutanol biosynthesis (engineered)";"L-phenylalanine degradation III";"Salidroside biosynthesis";"Ethanol oxidation";"Chitin degradation to ethanol";"Serotonin degradation";"L-tryptophan degradation V (side chain pathway)";"Pyruvate fermentation to isobutanol (engineered)";"L-leucine degradation III";"Chloroalkane and chloroalkene degradation";"Phenylethanol biosynthesis";"Glycine, serine and threonine metabolism";"(S)-propane-1,2-diol degradation";"Acetaldehyde biosynthesis I";"Tyrosine metabolism";"Naphthalene degradation";"Pyruvate fermentation to ethanol II";"Methane metabolism";"3-methylbutanol biosynthesis (engineered)";"L-isoleucine degradation II";"Metabolism of xenobiotics by cytochrome P450";"Pyruvate fermentation to ethanol I";"Glycolysis / Gluconeogenesis";"Retinol metabolism";"L-methionine degradation III";"alpha-Linolenic acid metabolism" XP_030026429.1 4 MetaCyc: PWY-6483;Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119 "Ceramide degradation (generic)";"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)" XP_037297329.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037292681.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_030022192.1 2 Reactome: R-HSA-6803205;Reactome: R-HSA-8873719 "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation" XP_030025183.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_037297157.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_030030457.1 2 Reactome: R-HSA-162588;Reactome: R-HSA-917729 "Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_037292756.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_030020317.2 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_030029137.1 4 Reactome: R-HSA-389661;Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-77289 "Glyoxylate metabolism and glycine degradation";"Respiratory electron transport";"Complex I biogenesis";"Mitochondrial Fatty Acid Beta-Oxidation" XP_030038232.2 11 Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-1251985;Reactome: R-HSA-205043;Reactome: R-HSA-2122948;Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3" XP_030040231.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823 "Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation" XP_037301997.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037300989.1 24 Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-1445148;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434 "The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Kinesins";"Recycling pathway of L1";"Mitotic Prometaphase";"Aggrephagy";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"Cilium Assembly";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic" XP_030037348.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037294600.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_030040373.2 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037295908.1 8 MetaCyc: PWY-6174;Reactome: R-HSA-1989781;Reactome: R-HSA-191273;KEGG: 00900+1.1.1.34;MetaCyc: PWY-7391;MetaCyc: PWY-7524;MetaCyc: PWY-922;Reactome: R-HSA-2426168 "Mevalonate pathway II (archaea)";"PPARA activates gene expression";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)" XP_037295338.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037292610.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_030025112.2 16 Reactome: R-HSA-8853884;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-174048;Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-179409 "Transcriptional Regulation by VENTX";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A" XP_037293759.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_030036116.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_037295339.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037293612.1 2 Reactome: R-HSA-6802953;Reactome: R-HSA-5658442 "RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs" XP_030029399.2 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_030021592.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_037295787.1 6 Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-201722;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-3769402 "Repression of WNT target genes";"Ca2+ pathway";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex" XP_037293644.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_037298068.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_030030438.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_037295875.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_030020921.1 15 MetaCyc: PWY-7218;KEGG: 00230+2.7.1.40;MetaCyc: PWY-5723;MetaCyc: PWY-6886;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-8004;KEGG: 00620+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383 "Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Purine metabolism";"Rubisco shunt";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Pyruvate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_030020210.2 7 Reactome: R-HSA-9609690;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-8953750;Reactome: R-HSA-212300;Reactome: R-HSA-8943724;Reactome: R-HSA-3214841 "HCMV Early Events";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional Regulation by E2F6";"PRC2 methylates histones and DNA";"Regulation of PTEN gene transcription";"PKMTs methylate histone lysines" XP_037296126.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_037292979.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_030019883.2 8 Reactome: R-HSA-141444;Reactome: R-HSA-6783310;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-606279;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Fanconi Anemia Pathway";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_037294746.1 11 Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-418597 "PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"PKA activation";"Purine metabolism";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events" XP_030030331.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_030020485.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037296569.1 1 Reactome: R-HSA-6785631 "ERBB2 Regulates Cell Motility" XP_030023189.2 44 Reactome: R-HSA-198753;Reactome: R-HSA-2559580;Reactome: R-HSA-881907;Reactome: R-HSA-9649948;Reactome: R-HSA-9627069;Reactome: R-HSA-445144;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-9635465;Reactome: R-HSA-5663213;Reactome: R-HSA-6802955;Reactome: R-HSA-170968;Reactome: R-HSA-982772;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-3371453;Reactome: R-HSA-112409;Reactome: R-HSA-6811558;Reactome: R-HSA-1295596;Reactome: R-HSA-5654732;Reactome: R-HSA-74749;Reactome: R-HSA-162658;Reactome: R-HSA-9634638;Reactome: R-HSA-5673001;Reactome: R-HSA-879415;Reactome: R-HSA-444257;Reactome: R-HSA-5654727;Reactome: R-HSA-6802948;Reactome: R-HSA-5654733;Reactome: R-HSA-2871796;Reactome: R-HSA-202670;Reactome: R-HSA-5674499;Reactome: R-HSA-375165;Reactome: R-HSA-8939211;Reactome: R-HSA-2029482;Reactome: R-HSA-456926;Reactome: R-HSA-5668599;Reactome: R-HSA-8943724;Reactome: R-HSA-2559582;Reactome: R-HSA-8940973;Reactome: R-HSA-5674135;Reactome: R-HSA-2559585;Reactome: R-HSA-5675221;Reactome: R-HSA-5654726 "ERK/MAPK targets";"Oxidative Stress Induced Senescence";"Gastrin-CREB signalling pathway via PKC and MAPK";"Signaling downstream of RAS mutants";"Regulation of the apoptosome activity";"Signal transduction by L1";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Suppression of apoptosis";"RHO GTPases Activate WASPs and WAVEs";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Frs2-mediated activation";"Growth hormone receptor signaling";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"Regulation of HSF1-mediated heat shock response";"RAF-independent MAPK1/3 activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Spry regulation of FGF signaling";"Negative regulation of FGFR3 signaling";"Signal attenuation";"Golgi Cisternae Pericentriolar Stack Reorganization";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RAF/MAP kinase cascade";"Advanced glycosylation endproduct receptor signaling";"RSK activation";"Negative regulation of FGFR2 signaling";"Signaling by high-kinase activity BRAF mutants";"Negative regulation of FGFR4 signaling";"FCERI mediated MAPK activation";"ERKs are inactivated";"Negative feedback regulation of MAPK pathway";"NCAM signaling for neurite out-growth";"ESR-mediated signaling";"Regulation of actin dynamics for phagocytic cup formation";"Thrombin signalling through proteinase activated receptors (PARs)";"RHO GTPases Activate NADPH Oxidases";"Regulation of PTEN gene transcription";"Senescence-Associated Secretory Phenotype (SASP)";"RUNX2 regulates osteoblast differentiation";"MAP2K and MAPK activation";"Oncogene Induced Senescence";"Negative regulation of MAPK pathway";"Negative regulation of FGFR1 signaling" XP_037297785.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_030020008.1 3 MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367 "3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism" XP_030041109.1 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_037301831.1 12 KEGG: 05165+2.7.11.1;Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_037293566.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037301139.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_030022481.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_030033987.2 3 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_030036428.1 4 MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6902 "Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)" XP_030031020.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_030026534.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_030038652.2 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_030029314.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_037292673.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030021002.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_030038840.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_030027444.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037297235.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_037292490.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037303085.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_030029018.1 3 Reactome: R-HSA-450604;Reactome: R-HSA-429947;Reactome: R-HSA-380994 "KSRP (KHSRP) binds and destabilizes mRNA";"Deadenylation of mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_030035110.2 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_030032565.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_037295517.1 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" XP_030036049.2 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_037298402.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_030024826.2 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_030034183.2 6 Reactome: R-HSA-5651801;Reactome: R-HSA-5685939;Reactome: R-HSA-174437;Reactome: R-HSA-110362;Reactome: R-HSA-69166;Reactome: R-HSA-162594 "PCNA-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)";"Removal of the Flap Intermediate from the C-strand";"POLB-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate";"Early Phase of HIV Life Cycle" XP_030024952.2 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_030035724.2 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_030026705.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_030021267.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030020936.1 1 Reactome: R-HSA-5689896 "Ovarian tumor domain proteases" XP_037295111.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_037300533.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-1268020 "Cristae formation";"Mitochondrial protein import" XP_037300034.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_030024755.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037294967.1 5 Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-110328;Reactome: R-HSA-5221030;Reactome: R-HSA-110357 "Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1" XP_037300776.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037295573.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_030033910.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_037293339.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_030035175.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_030025476.2 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_030023670.1 8 KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1 "Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Galactose metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis" XP_030027258.1 10 Reactome: R-HSA-2206292;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2160916 "MPS VII - Sly syndrome";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"HS-GAG degradation";"Sphingolipid metabolism";"Neutrophil degranulation";"Galactose metabolism";"Hyaluronan uptake and degradation" XP_030028606.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_037292487.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037299916.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_030029674.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_030024982.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_030021858.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_030025106.1 11 KEGG: 00760+3.6.1.9;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7206;MetaCyc: PWY-7187;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00770+3.6.1.9;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00500+3.6.1.9;MetaCyc: PWY-6545 "Nicotinate and nicotinamide metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Riboflavin metabolism";"Tunicamycin biosynthesis";"Pantothenate and CoA biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" XP_030032936.1 4 Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957 "Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_037297775.1 9 Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73776 "HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape" XP_037294922.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_037300986.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_037297952.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression" XP_037303366.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037298025.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_030041103.2 10 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-201722;Reactome: R-HSA-3214847;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"Ub-specific processing proteases";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones";"Human immunodeficiency virus 1 infection" XP_030021774.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_037303365.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_030036369.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037303567.1 7 Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76066 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_030021595.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_037302526.1 2 Reactome: R-HSA-3214815;Reactome: R-HSA-427413 "HDACs deacetylate histones";"NoRC negatively regulates rRNA expression" XP_037301777.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_030037352.2 14 Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7724 "Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_037300839.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037292348.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037292929.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_037296184.1 1 Reactome: R-HSA-437239 "Recycling pathway of L1" XP_030032036.1 6 MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-3341;MetaCyc: PWY-6344;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6922 "L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis" XP_030023467.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_030030756.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs" XP_037292933.1 5 Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;Reactome: R-HSA-450321;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24 "Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway" XP_037292893.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_030036006.1 8 Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-5610787;Reactome: R-HSA-442720 "PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state";"CREB1 phosphorylation through the activation of Adenylate Cyclase" XP_037295010.1 13 MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52 "Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series" XP_030022210.1 5 Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855 "Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)" XP_037301244.1 11 KEGG: 05170+2.7.11.1;Reactome: R-HSA-163680;KEGG: 04714+2.7.11.1;Reactome: R-HSA-380972;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9614657;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804756 "Human immunodeficiency virus 1 infection";"AMPK inhibits chREBP transcriptional activation activity";"Thermogenesis";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human cytomegalovirus infection";"mTOR signaling pathway";"FOXO-mediated transcription of cell death genes";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Regulation of TP53 Activity through Phosphorylation" XP_030023255.1 7 Reactome: R-HSA-168333;Reactome: R-HSA-1655829;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-203927 "NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"MicroRNA (miRNA) biogenesis" XP_037295374.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_030028120.2 15 KEGG: 00230+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-6886;MetaCyc: PWY-5723;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-2221;MetaCyc: PWY-8004;KEGG: 00620+2.7.1.40;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-6142;MetaCyc: PWY-6901;MetaCyc: PWY-5484 "Purine metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Glycolysis";"Glycerol degradation to butanol";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)" XP_030030246.2 9 Reactome: R-HSA-69205;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68867 "G1/S-Specific Transcription";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex" XP_030032221.2 14 Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-69091;Reactome: R-HSA-5655862 "Translesion synthesis by POLI";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching";"Translesion synthesis by POLK" XP_030026685.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_030024430.1 6 MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085 "Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_030029005.1 3 Reactome: R-HSA-6784531;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470 "tRNA processing in the nucleus";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion" XP_037303240.1 56 Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_030034182.2 22 MetaCyc: PWY-6142;Reactome: R-HSA-6798695;KEGG: 00520+5.3.1.9;MetaCyc: PWY-7385;MetaCyc: PWY-5054;KEGG: 00010+5.3.1.9;MetaCyc: PWY-8013;MetaCyc: PWY-5384;MetaCyc: PWY-622;MetaCyc: PWY-6992;MetaCyc: PWY-5514;MetaCyc: PWY-6981;Reactome: R-HSA-5628897;KEGG: 00030+5.3.1.9;MetaCyc: PWY-7238;Reactome: R-HSA-70263;MetaCyc: PWY-621;Reactome: R-HSA-70171;MetaCyc: PWY-5659;MetaCyc: PWY-7347;KEGG: 00500+5.3.1.9;MetaCyc: PWY-3801 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Neutrophil degranulation";"Amino sugar and nucleotide sugar metabolism";"1,3-propanediol biosynthesis (engineered)";"D-sorbitol biosynthesis I";"Glycolysis / Gluconeogenesis";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Sucrose degradation IV (sucrose phosphorylase)";"Starch biosynthesis";"1,5-anhydrofructose degradation";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin biosynthesis";"TP53 Regulates Metabolic Genes";"Pentose phosphate pathway";"Sucrose biosynthesis II";"Gluconeogenesis";"Sucrose degradation III (sucrose invertase)";"Glycolysis";"GDP-mannose biosynthesis";"Sucrose biosynthesis III";"Starch and sucrose metabolism";"Sucrose degradation II (sucrose synthase)" XP_030025896.1 31 MetaCyc: PWY-7663;MetaCyc: PWY-5366;Reactome: R-HSA-199220;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5147;MetaCyc: PWY-5994;MetaCyc: PWY-5971;MetaCyc: PWY-7388;MetaCyc: PWY-5142;Reactome: R-HSA-75105;MetaCyc: PWY-5989;MetaCyc: PWY-5973;MetaCyc: PWY-7858;MetaCyc: PWYG-321;Reactome: R-HSA-2426168;MetaCyc: PWY-8012;MetaCyc: PWY-8047;MetaCyc: PWY-7746;MetaCyc: PWY-5966-1;MetaCyc: PWY-6113;MetaCyc: PWY-8049;MetaCyc: PWY-7723;Reactome: R-HSA-9029558;MetaCyc: PWY-6282;MetaCyc: PWY-5367;MetaCyc: PWY-7664;MetaCyc: PWY-4381;MetaCyc: PWY-6799;MetaCyc: PWY-6519;Reactome: R-HSA-163765;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41 "Gondoate biosynthesis (anaerobic)";"Palmitoleate biosynthesis II (plants and bacteria)";"Vitamin B5 (pantothenate) metabolism";"Fatty acid biosynthesis";"Oleate biosynthesis I (plants)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acyl-CoA biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Cis-vaccenate biosynthesis";"(5Z)-dodecenoate biosynthesis II";"";"Activation of gene expression by SREBF (SREBP)";"Mupirocin biosynthesis";"Bryostatin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Superpathway of mycolate biosynthesis";"Pederin biosynthesis";"Bacterial bioluminescence";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Petroselinate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"8-amino-7-oxononanoate biosynthesis I";"ChREBP activates metabolic gene expression";"Biotin metabolism" XP_030022319.2 2 Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22 "Histidine catabolism";"Histidine metabolism" XP_030034294.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_030040597.1 2 Reactome: R-HSA-8953750;Reactome: R-HSA-8939243 "Transcriptional Regulation by E2F6";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_030027019.2 4 Reactome: R-HSA-947581;Reactome: R-HSA-1362409;KEGG: 00730+2.8.1.7;MetaCyc: PWY-7250 "Molybdenum cofactor biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Thiamine metabolism";"[2Fe-2S] iron-sulfur cluster biosynthesis" XP_030023966.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_030030510.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_030038133.2 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037292885.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway" XP_030026363.2 11 Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-167246 "Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript" XP_030024644.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_030019699.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_030020510.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_030038038.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_030031614.2 2 KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_030040122.2 5 Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-174490 "HCMV Late Events";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins" XP_030032456.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030023668.1 8 KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1 "Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Fructose and mannose metabolism" XP_030039417.1 6 Reactome: R-HSA-111367;Reactome: R-HSA-191859;Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-77588 "SLBP independent Processing of Histone Pre-mRNAs";"snRNP Assembly";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" XP_030033504.2 7 MetaCyc: PWY-5695;KEGG: 00983+1.1.1.205;MetaCyc: PWY-6596;MetaCyc: PWY-7221;KEGG: 00230+1.1.1.205;Reactome: R-HSA-6798695;Reactome: R-HSA-73817 "Inosine 5'-phosphate degradation";"Drug metabolism - other enzymes";"Adenosine nucleotides degradation I";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Neutrophil degranulation";"Purine ribonucleoside monophosphate biosynthesis" XP_037299288.1 5 KEGG: 00564+2.7.7.41;MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5981 "Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III" XP_037301964.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-6784531;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595 "mRNA Splicing - Major Pathway";"tRNA processing in the nucleus";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs" XP_030040485.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_030035251.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_037297953.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340 "PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_030030635.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226 "Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_030019995.1 13 MetaCyc: PWY-6842;MetaCyc: PWY-6370;MetaCyc: PWY-7112;KEGG: 00982+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-2261;Reactome: R-HSA-156590;KEGG: 00980+2.5.1.18;Reactome: R-HSA-196836;KEGG: 00053+1.8.5.1;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-4061 "Glutathione-mediated detoxification II";"Ascorbate recycling (cytosolic)";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - cytochrome P450";"Glutathione metabolism";"Ascorbate glutathione cycle";"Glutathione conjugation";"Metabolism of xenobiotics by cytochrome P450";"Vitamin C (ascorbate) metabolism";"Ascorbate and aldarate metabolism";"Drug metabolism - other enzymes";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I" XP_037301543.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037293746.1 4 Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-8866654 "RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins" XP_030032121.1 4 Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037301390.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_037302426.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_030022961.1 56 Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-8939236;Reactome: R-HSA-8939902;Reactome: R-HSA-69601;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-180585;Reactome: R-HSA-174154;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-382556 "Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Degradation of DVL";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX2 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G";"APC/C:Cdc20 mediated degradation of Securin";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport" XP_037294923.1 4 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315;KEGG: 00908+2.5.1.75;MetaCyc: PWY-2781 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol";"Zeatin biosynthesis";"Cis-zeatin biosynthesis" XP_030041257.1 3 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109 "Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis" XP_030023683.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_037292643.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_037299355.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037303183.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-68884;Reactome: R-HSA-2132295;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Telophase/Cytokinesis";"MHC class II antigen presentation";"Kinesins" XP_037292597.1 12 KEGG: 00051+4.1.2.13;MetaCyc: PWY-5484;MetaCyc: PWY-7385;MetaCyc: PWY-6142;MetaCyc: PWY-1861;KEGG: 00710+4.1.2.13;KEGG: 00010+4.1.2.13;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1042;Reactome: R-HSA-70171;Reactome: R-HSA-70263;KEGG: 00680+4.1.2.13 "Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Glycolysis";"Gluconeogenesis";"Methane metabolism" XP_030025001.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037295186.1 5 Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_030020002.1 13 MetaCyc: PWY-7112;MetaCyc: PWY-6370;MetaCyc: PWY-2261;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00053+1.8.5.1;Reactome: R-HSA-196836;MetaCyc: PWY-7533;MetaCyc: PWY-4061;KEGG: 00983+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00980+2.5.1.18 "4-hydroxy-2-nonenal detoxification";"Ascorbate recycling (cytosolic)";"Ascorbate glutathione cycle";"Glutathione metabolism";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II";"Ascorbate and aldarate metabolism";"Vitamin C (ascorbate) metabolism";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"Drug metabolism - other enzymes";"Glutathione conjugation";"Metabolism of xenobiotics by cytochrome P450" XP_030037376.1 7 MetaCyc: PWY-7184;MetaCyc: PWY-7185;MetaCyc: PWY-7210;MetaCyc: PWY-6545;MetaCyc: PWY-7198;KEGG: 00230+3.6.1.15;KEGG: 00730+3.6.1.15 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Thiamine metabolism" XP_037299825.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037298581.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037298041.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_030032401.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_030028540.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037299984.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_030026960.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_037294096.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_037299477.1 5 Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2 "Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation" XP_030033358.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030025237.2 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_030032032.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_030036196.1 9 KEGG: 00130+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00401+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00360+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00270+2.6.1.5 "Ubiquinone and other terpenoid-quinone biosynthesis";"Isoquinoline alkaloid biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Tyrosine metabolism";"Novobiocin biosynthesis";"Tyrosine catabolism";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Cysteine and methionine metabolism" XP_030031078.2 8 Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-69166 "Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Telomere C-strand synthesis initiation";"Polymerase switching";"Activation of the pre-replicative complex";"DNA replication initiation";"Removal of the Flap Intermediate" XP_030026230.1 24 Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-9648025 "Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"HCMV Early Events";"Cilium Assembly";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"Aggrephagy";"Recycling pathway of L1";"Mitotic Prometaphase";"Kinesins";"EML4 and NUDC in mitotic spindle formation" XP_030021965.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_030025221.2 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037302119.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_030020329.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037300215.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030021570.1 2 Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2 "Glycine degradation";"Glycine, serine and threonine metabolism" XP_037297575.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_030026018.1 2 Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14 "Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms" XP_037302584.1 3 Reactome: R-HSA-196757;MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17 "Metabolism of folate and pterines";"Folate polyglutamylation";"Folate biosynthesis" XP_037296295.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_037303569.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_037292672.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030036752.1 4 Reactome: R-HSA-1632852;Reactome: R-HSA-5205685;Reactome: R-HSA-8934903;Reactome: R-HSA-936440 "Macroautophagy";"Pink/Parkin Mediated Mitophagy";"Receptor Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling" XP_030019901.2 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_030034442.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037292276.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_030029619.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_030034137.2 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2299718 "Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes" XP_037292680.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_030034968.2 5 Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-390450 "Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC" XP_037299297.1 5 Reactome: R-HSA-5689880;Reactome: R-HSA-5545619;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-201681 "Ub-specific processing proteases";"XAV939 inhibits tankyrase, stabilizing AXIN";"Degradation of AXIN";"Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT" XP_030021653.1 6 Reactome: R-HSA-9033241;Reactome: R-HSA-9615017;Reactome: R-HSA-6798695;Reactome: R-HSA-3299685;KEGG: 00630+1.11.1.6;KEGG: 00380+1.11.1.6 "Peroxisomal protein import";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Neutrophil degranulation";"Detoxification of Reactive Oxygen Species";"Glyoxylate and dicarboxylate metabolism";"Tryptophan metabolism" XP_037300816.1 7 MetaCyc: PWY-6121;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6122;KEGG: 00230+2.4.2.14;Reactome: R-HSA-73817;MetaCyc: PWY-6277;MetaCyc: PWY-7282 "5-aminoimidazole ribonucleotide biosynthesis I";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis" XP_030041074.2 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_037293242.1 9 MetaCyc: PWY-6983;Reactome: R-HSA-1474151;KEGG: 00790+3.5.4.16;MetaCyc: PWY-7442;MetaCyc: PWY-5663;MetaCyc: PWY-6147;MetaCyc: PWY-7852;MetaCyc: PWY-5664;MetaCyc: PWY-6703 "Threo-tetrahydrobiopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Erythro-tetrahydrobiopterin biosynthesis II";"Preq0 biosynthesis" XP_030034432.2 1 Reactome: R-HSA-6804756 "Regulation of TP53 Activity through Phosphorylation" XP_037297166.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037296728.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_030028838.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_030040672.2 5 Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-109704 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"PI3K Cascade" XP_037300638.1 5 KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22 "Glycerolipid metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Galactose metabolism" XP_030029346.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_030039842.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037303385.1 5 Reactome: R-HSA-3371497;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Neutrophil degranulation";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic" XP_037294365.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037297497.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_030021537.1 14 MetaCyc: PWY-7589;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-5981;MetaCyc: PWY-6453;MetaCyc: PWY-7782;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7411 "Palmitoleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)" XP_037302559.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway" XP_030021983.2 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_037297860.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030023723.2 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_037295437.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-983231 "Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production" XP_030038300.1 8 Reactome: R-HSA-9633012;Reactome: R-HSA-8943724;Reactome: R-HSA-450341;Reactome: R-HSA-6796648;Reactome: R-HSA-400253;Reactome: R-HSA-3214847;Reactome: R-HSA-9018519;Reactome: R-HSA-2151201 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of PTEN gene transcription";"Activation of the AP-1 family of transcription factors";"TP53 Regulates Transcription of DNA Repair Genes";"Circadian Clock";"HATs acetylate histones";"Estrogen-dependent gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_030025928.1 12 MetaCyc: PWY-7238;MetaCyc: PWY-3801;KEGG: 00500+2.7.7.9;MetaCyc: PWY-6527;MetaCyc: PWY-7343;KEGG: 00561+2.7.7.9;KEGG: 00040+2.7.7.9;Reactome: R-HSA-173599;Reactome: R-HSA-3322077;KEGG: 00052+2.7.7.9;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7817 "Sucrose biosynthesis II";"Sucrose degradation II (sucrose synthase)";"Starch and sucrose metabolism";"Stachyose degradation";"UDP-alpha-D-glucose biosynthesis I";"Glycerolipid metabolism";"Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate";"Glycogen synthesis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_030040380.1 3 Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689 "tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I" XP_037302155.1 3 KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221 "Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis" XP_030037856.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030034328.2 57 Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-69601;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-174154;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-9020702;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-195253;Reactome: R-HSA-5610780 "FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Interleukin-1 signaling";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome" XP_030040898.2 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_030025163.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_030031398.1 4 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling" XP_030034049.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_037292615.1 4 KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737;Reactome: R-HSA-70688;MetaCyc: PWY-6922 "Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism";"L-Ndelta-acetylornithine biosynthesis" XP_037297379.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_037292556.1 3 Reactome: R-HSA-8953750;Reactome: R-HSA-73772;Reactome: R-HSA-427389 "Transcriptional Regulation by E2F6";"RNA Polymerase I Promoter Escape";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_030041143.1 4 Reactome: R-HSA-72086;Reactome: R-HSA-77075;MetaCyc: PWY-7375;Reactome: R-HSA-167160 "mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection" XP_030039553.1 9 Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-6804756 "RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation" XP_030025063.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037296673.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030022927.1 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" XP_037294014.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037297337.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-2408508 "Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_037299005.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_030021771.2 5 Reactome: R-HSA-5221030;Reactome: R-HSA-3108214;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110357 "TET1,2,3 and TDG demethylate DNA";"SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1" XP_030023204.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_037300178.1 3 Reactome: R-HSA-156590;Reactome: R-HSA-204174;Reactome: R-HSA-8963684 "Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism" XP_037302111.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037293373.1 4 Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165 "RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth" XP_030030198.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_030021660.1 8 KEGG: 00350+1.14.16.2;KEGG: 00790+1.14.16.2;MetaCyc: PWY-6133;MetaCyc: PWY-5049;MetaCyc: PWY-5394;KEGG: 00950+1.14.16.2;Reactome: R-HSA-209905;MetaCyc: PWY-3581 "Tyrosine metabolism";"Folate biosynthesis";"(S)-reticuline biosynthesis II";"Rosmarinic acid biosynthesis II";"Betalamic acid biosynthesis";"Isoquinoline alkaloid biosynthesis";"Catecholamine biosynthesis";"(S)-reticuline biosynthesis I" XP_030019582.2 15 Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167200 "Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_030027034.2 5 KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;MetaCyc: PWY-6749 "Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"CMP-legionaminate biosynthesis I" XP_037298640.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_037300468.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_030039250.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030024786.2 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_030021654.1 1 Reactome: R-HSA-428359 "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA" XP_030028466.1 5 KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22 "Galactose metabolism";"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Sphingolipid metabolism" XP_037303191.1 13 Reactome: R-HSA-5578775;Reactome: R-HSA-2871809;Reactome: R-HSA-5607763;Reactome: R-HSA-112043;Reactome: R-HSA-2029485;Reactome: R-HSA-139853;Reactome: R-HSA-114508;Reactome: R-HSA-381676;Reactome: R-HSA-4086398;Reactome: R-HSA-422356;Reactome: R-HSA-983695;Reactome: R-HSA-1489509;Reactome: R-HSA-5218921 "Ion homeostasis";"FCERI mediated Ca+2 mobilization";"CLEC7A (Dectin-1) induces NFAT activation";"PLC beta mediated events";"Role of phospholipids in phagocytosis";"Elevation of cytosolic Ca2+ levels";"Effects of PIP2 hydrolysis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway";"Regulation of insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"DAG and IP3 signaling";"VEGFR2 mediated cell proliferation" XP_037299057.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_030024548.2 12 KEGG: 00380+2.6.1.7;KEGG: 00450+4.4.1.13;MetaCyc: PWY-1187;MetaCyc: PWY-6936;MetaCyc: PWY-7901;Reactome: R-HSA-71240;MetaCyc: PWY-6309;KEGG: 00270+4.4.1.13;MetaCyc: PWY-6842;MetaCyc: PWY-2821;MetaCyc: PWY-801;MetaCyc: PWY-601 "Tryptophan metabolism";"Selenocompound metabolism";"Glucosinolate biosynthesis from homomethionine";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from tyrosine";"Tryptophan catabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Cysteine and methionine metabolism";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from phenylalanine";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from tryptophan" XP_030020496.2 6 MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system" XP_030031485.1 1 Reactome: R-HSA-1483166 "Synthesis of PA" XP_037294248.1 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_030020643.1 11 MetaCyc: PWY-5497;Reactome: R-HSA-8851680;Reactome: R-HSA-74259;MetaCyc: PWY-6606;MetaCyc: PWY-6538;MetaCyc: PWY-6608;MetaCyc: PWY-6596;MetaCyc: PWY-6999;MetaCyc: PWY-5695;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6607 "Purine nucleobases degradation II (anaerobic)";"Butyrophilin (BTN) family interactions";"Purine catabolism";"Guanosine nucleotides degradation II";"Caffeine degradation III (bacteria, via demethylation)";"Guanosine nucleotides degradation III";"Adenosine nucleotides degradation I";"Theophylline degradation";"Inosine 5'-phosphate degradation";"Purine metabolism";"Guanosine nucleotides degradation I" XP_030024673.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_037298913.1 3 KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis" XP_037302953.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_030021891.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_030038469.2 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_030030339.1 5 Reactome: R-HSA-6811434;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-204005 "COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic";"COPII-mediated vesicle transport" XP_037300493.1 14 MetaCyc: PWY-7782;Reactome: R-HSA-1483166;MetaCyc: PWY-7589;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-7587 "Plasmalogen biosynthesis";"Synthesis of PA";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)" XP_037300152.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_030029216.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037301583.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_030020133.2 5 MetaCyc: PWY-7391;MetaCyc: PWY-922;KEGG: 00900+2.7.4.2;Reactome: R-HSA-2426168;Reactome: R-HSA-191273 "Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis" XP_030032912.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_030023594.2 1 Reactome: R-HSA-75153 "Apoptotic execution phase" XP_030031449.1 4 Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554 "Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_030025017.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_037297705.1 12 Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"HCMV Early Events";"Aggrephagy";"Mitotic Prometaphase";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_037297327.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_030037469.1 7 Reactome: R-HSA-171306;Reactome: R-HSA-1221632;Reactome: R-HSA-2559586;Reactome: R-HSA-110330;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110331 "Packaging Of Telomere Ends";"Meiotic synapsis";"DNA Damage/Telomere Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine" XP_030026508.2 13 MetaCyc: PWY-7182;MetaCyc: PWY-7410;MetaCyc: PWY-7141;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7102;MetaCyc: PWY-7736;MetaCyc: PWY-5122;MetaCyc: PWY-5123;MetaCyc: PWY-7659;MetaCyc: PWY-7721;MetaCyc: PWY-6859;MetaCyc: PWY-6383;MetaCyc: PWY-7709 "Linalool biosynthesis I";"Ipsdienol biosynthesis";"(3S)-linalool biosynthesis";"Terpenoid backbone biosynthesis";"Bisabolene biosynthesis (engineered)";"Stellatic acid biosynthesis";"Geranyl diphosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Viridicatumtoxin biosynthesis";"Methyl phomopsenoate biosynthesis";"All-trans-farnesol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"(3R)-linalool biosynthesis" XP_037292698.1 9 Reactome: R-HSA-5649702;Reactome: R-HSA-9657050;Reactome: R-HSA-110329;Reactome: R-HSA-110331;Reactome: R-HSA-110357;Reactome: R-HSA-9656256;Reactome: R-HSA-110330;Reactome: R-HSA-110328;Reactome: R-HSA-9656255 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Defective OGG1 Localization";"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1";"Defective OGG1 Substrate Processing";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective OGG1 Substrate Binding" XP_030035249.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_037296032.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_037302787.1 11 Reactome: R-HSA-5696400;Reactome: R-HSA-174430;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-68952;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-68962;Reactome: R-HSA-6782210 "Dual Incision in GG-NER";"Telomere C-strand synthesis initiation";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"DNA replication initiation";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_030032899.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_037302923.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_030023015.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_037302698.1 6 KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;Reactome: R-HSA-4793952;MetaCyc: PWY-7920;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143 "Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis" XP_037294050.1 4 Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-8943724 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription" XP_037299556.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_030034542.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_030024311.1 18 Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-75955 "Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Elongation" XP_030038424.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037293727.1 8 Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897 "Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"Macroautophagy";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes" XP_030028313.2 5 Reactome: R-HSA-389661;KEGG: 00280+1.2.4.4;Reactome: R-HSA-70895;KEGG: 00640+1.2.4.4;MetaCyc: PWY-5046 "Glyoxylate metabolism and glycine degradation";"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"Propanoate metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA" XP_037292690.1 6 Reactome: R-HSA-6803211;Reactome: R-HSA-6803204;Reactome: R-HSA-6803207;Reactome: R-HSA-6804759;Reactome: R-HSA-6803205;Reactome: R-HSA-139915 "TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria" XP_030022311.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030030663.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_030024250.1 2 Reactome: R-HSA-416482;Reactome: R-HSA-456926 "G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)" XP_030022844.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_030030162.1 5 Reactome: R-HSA-9627069;Reactome: R-HSA-111457;Reactome: R-HSA-111464;Reactome: R-HSA-111469;Reactome: R-HSA-111463 "Regulation of the apoptosome activity";"Release of apoptotic factors from the mitochondria";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC, XIAP-regulated apoptotic response";"SMAC (DIABLO) binds to IAPs" XP_030029388.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Association of TriC/CCT with target proteins during biosynthesis";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037297906.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037293500.1 7 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection" XP_030031098.2 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_030032278.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_030041007.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030022213.1 25 Reactome: R-HSA-456926;Reactome: R-HSA-418217;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-392170;Reactome: R-HSA-416482;Reactome: R-HSA-8964315;Reactome: R-HSA-418555;Reactome: R-HSA-9009391;Reactome: R-HSA-392451;Reactome: R-HSA-392851;Reactome: R-HSA-163359;Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-432040;Reactome: R-HSA-202040;Reactome: R-HSA-416476;Reactome: R-HSA-400042;Reactome: R-HSA-4086398;Reactome: R-HSA-381676;Reactome: R-HSA-8964616;Reactome: R-HSA-418597;Reactome: R-HSA-381771;Reactome: R-HSA-500657;Reactome: R-HSA-420092 "Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through PLC beta";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"ADP signalling through P2Y purinoceptor 12";"G alpha (12/13) signalling events";"G beta:gamma signalling through BTK";"G alpha (s) signalling events";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through PI3Kgamma";"Prostacyclin signalling through prostacyclin receptor";"Glucagon signaling in metabolic regulation";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"G-protein activation";"G alpha (q) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through CDC42";"G alpha (z) signalling events";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Presynaptic function of Kainate receptors";"Glucagon-type ligand receptors" XP_030035330.2 6 MetaCyc: PWY-6527;Reactome: R-HSA-70370;KEGG: 00520+2.7.7.12;Reactome: R-HSA-5609978;KEGG: 00052+2.7.7.12;MetaCyc: PWY-6317 "Stachyose degradation";"Galactose catabolism";"Amino sugar and nucleotide sugar metabolism";"Defective GALT can cause Galactosemia";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)" XP_030030249.2 6 Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-69052 "Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state" XP_030024532.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_030026247.1 16 Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72689 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits" XP_030029380.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037299903.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" XP_030020869.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_030027579.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827 "Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_030029870.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_030035200.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_030033282.1 6 KEGG: 00030+5.1.3.1;KEGG: 00710+5.1.3.1;Reactome: R-HSA-71336;MetaCyc: PWY-1861;KEGG: 00040+5.1.3.1;MetaCyc: PWY-5723 "Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose and glucuronate interconversions";"Rubisco shunt" XP_037301953.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_030021605.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_037297305.1 19 Reactome: R-HSA-3214858;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-8876725;Reactome: R-HSA-6790901;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764 "RMTs methylate histone arginines";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Protein methylation";"rRNA modification in the nucleus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination" XP_030034441.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037302441.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030031814.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037296265.1 6 Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968;Reactome: R-HSA-6796648;Reactome: R-HSA-5358606;Reactome: R-HSA-5632927 "Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6";"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MSH3" XP_030022284.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_037301054.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037298146.1 15 Reactome: R-HSA-9009391;Reactome: R-HSA-912631;Reactome: R-HSA-388841;Reactome: R-HSA-6811558;Reactome: R-HSA-114604;Reactome: R-HSA-1266695;Reactome: R-HSA-2219530;Reactome: R-HSA-1433557;Reactome: R-HSA-8853659;Reactome: R-HSA-912526;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-512988;Reactome: R-HSA-1660499;Reactome: R-HSA-416476 "Extra-nuclear estrogen signaling";"Regulation of signaling by CBL";"Costimulation by the CD28 family";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"GPVI-mediated activation cascade";"Interleukin-7 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by SCF-KIT";"RET signaling";"Interleukin receptor SHC signaling";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Synthesis of PIPs at the plasma membrane";"G alpha (q) signalling events" XP_037297239.1 3 Reactome: R-HSA-1660662;Reactome: R-HSA-193681;Reactome: R-HSA-5626978 "Glycosphingolipid metabolism";"Ceramide signalling";"TNFR1-mediated ceramide production" XP_030023016.1 3 Reactome: R-HSA-2206291;Reactome: R-HSA-6798695;Reactome: R-HSA-2024096 "MPS IIIC - Sanfilippo syndrome C";"Neutrophil degranulation";"HS-GAG degradation" XP_030026229.1 24 Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-9648025;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332 "Aggrephagy";"Mitotic Prometaphase";"Recycling pathway of L1";"EML4 and NUDC in mitotic spindle formation";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin" XP_037299974.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_037300112.1 8 Reactome: R-HSA-70635;KEGG: 00220+6.3.4.5;MetaCyc: PWY-4984;MetaCyc: PWY-5154;KEGG: 00250+6.3.4.5;MetaCyc: PWY-4983;MetaCyc: PWY-7400;MetaCyc: PWY-5 "Urea cycle";"Arginine biosynthesis";"Urea cycle";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"Nitric oxide biosynthesis II (mammals)";"L-arginine biosynthesis IV (archaebacteria)";"Canavanine biosynthesis" XP_030032472.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_030036523.1 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" XP_030026441.1 2 Reactome: R-HSA-70350;Reactome: R-HSA-168928 "Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta" XP_037303449.1 5 Reactome: R-HSA-2426168;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-381183;Reactome: R-HSA-380994 "Activation of gene expression by SREBF (SREBP)";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_037299145.1 19 Reactome: R-HSA-432142;Reactome: R-HSA-975634;Reactome: R-HSA-8964046;Reactome: R-HSA-3000484;Reactome: R-HSA-8856825;Reactome: R-HSA-5686938;Reactome: R-HSA-3000471;Reactome: R-HSA-8866423;Reactome: R-HSA-3000497;Reactome: R-HSA-202733;Reactome: R-HSA-8964026;Reactome: R-HSA-8963901;Reactome: R-HSA-8964041;Reactome: R-HSA-8957275;Reactome: R-HSA-3000480;Reactome: R-HSA-381426;Reactome: R-HSA-8856828;Reactome: R-HSA-8964038;Reactome: R-HSA-8963888 "Platelet sensitization by LDL";"Retinoid metabolism and transport";"VLDL clearance";"Scavenging by Class F Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"Scavenging by Class B Receptors";"VLDL assembly";"Scavenging by Class H Receptors";"Cell surface interactions at the vascular wall";"Chylomicron clearance";"Chylomicron remodeling";"LDL remodeling";"Post-translational protein phosphorylation";"Scavenging by Class A Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Clathrin-mediated endocytosis";"LDL clearance";"Chylomicron assembly" XP_037299155.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030038169.1 3 Reactome: R-HSA-156590;Reactome: R-HSA-204174;Reactome: R-HSA-8963684 "Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism" XP_037301935.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_030030702.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030030622.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_030030170.1 5 MetaCyc: PWY-6168;MetaCyc: PWY-5523;Reactome: R-HSA-196843;KEGG: 00740+2.7.1.26;MetaCyc: PWY-7863 "Flavin biosynthesis III (fungi)";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Vitamin B2 (riboflavin) metabolism";"Riboflavin metabolism";"Roseoflavin biosynthesis" XP_037303464.1 6 KEGG: 00562+3.1.3.64+3.1.3.95;MetaCyc: PWY-6580;MetaCyc: PWY-6368;MetaCyc: PWY-6367;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.64+3.1.3.95 "Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)";"3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system" XP_037300182.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_030033713.1 7 Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2660826 "Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant" XP_037297789.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_030036449.1 6 MetaCyc: PWY-7511;Reactome: R-HSA-8939902;Reactome: R-HSA-8863795;Reactome: R-HSA-2173788;Reactome: R-HSA-8948751;Reactome: R-HSA-983168 "Protein ubiquitination";"Regulation of RUNX2 expression and activity";"Downregulation of ERBB2 signaling";"Downregulation of TGF-beta receptor signaling";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037293368.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins" XP_037292373.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_030031465.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_030030439.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_030036616.2 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_030020091.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722 "NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex" XP_030037831.1 7 KEGG: 00510+2.7.8.15;MetaCyc: PWY-6470;Reactome: R-HSA-446193;MetaCyc: PWY-5265;Reactome: R-HSA-4549356;KEGG: 00550+2.7.8.13;MetaCyc: PWY-6471 "N-Glycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis II (staphylococci)";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)" XP_037300266.1 14 MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-5981;MetaCyc: PWY-6453;MetaCyc: PWY-7589;KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667 "Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Stigma estolide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Synthesis of PA";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I" XP_037302227.1 4 MetaCyc: PWY-4841;Reactome: R-HSA-1855183;KEGG: 00562+1.13.99.1;KEGG: 00053+1.13.99.1 "UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Ascorbate and aldarate metabolism" XP_037293629.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037293569.1 5 Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_030036315.1 4 KEGG: 00510+2.4.1.257+2.4.1.132;KEGG: 00513+2.4.1.257+2.4.1.132;Reactome: R-HSA-446193;Reactome: R-HSA-4549349 "N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG2 causes ALG2-CDG (CDG-1i)" XP_030035432.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_037292697.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037293348.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037302607.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_030031235.1 14 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-450520;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-69273;Reactome: R-HSA-9634638;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-168333;Reactome: R-HSA-3769402;Reactome: R-HSA-5687128;Reactome: R-HSA-2173788 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"HuR (ELAVL1) binds and stabilizes mRNA";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Cyclin A/B1/B2 associated events during G2/M transition";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery";"Deactivation of the beta-catenin transactivating complex";"MAPK6/MAPK4 signaling";"Downregulation of TGF-beta receptor signaling" XP_037295132.1 1 Reactome: R-HSA-375276 "Peptide ligand-binding receptors" XP_030028781.1 6 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166;MetaCyc: PWY-5269;MetaCyc: PWY-5668;KEGG: 00564+2.7.8.5;MetaCyc: PWY-7817 "Synthesis of PG";"Synthesis of PA";"Cardiolipin biosynthesis II";"Cardiolipin biosynthesis I";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_030035157.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_030021764.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_037303276.1 4 MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6902 "Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)" XP_037302063.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037292970.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_030036662.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030031097.2 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_037293131.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_037300908.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_030022788.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" XP_037302543.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037294463.1 13 KEGG: 04150+2.7.11.1;Reactome: R-HSA-6802955;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9649948;Reactome: R-HSA-6802948;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6802946;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674135;Reactome: R-HSA-6802952;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Relaxin signaling pathway";"Signaling downstream of RAS mutants";"Signaling by high-kinase activity BRAF mutants";"PI3K-Akt signaling pathway";"Signaling by moderate kinase activity BRAF mutants";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions";"Human cytomegalovirus infection";"Thermogenesis" XP_030029867.1 5 MetaCyc: PWY-5381;MetaCyc: PWY-5653;Reactome: R-HSA-196807;KEGG: 00760+2.7.7.18;MetaCyc: PWY-7761 "Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)" XP_030038940.1 2 Reactome: R-HSA-375280;Reactome: R-HSA-416476 "Amine ligand-binding receptors";"G alpha (q) signalling events" XP_037300540.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_030023791.2 7 MetaCyc: PWY-6124;MetaCyc: PWY-7234;Reactome: R-HSA-73817;KEGG: 00230+4.3.2.2;KEGG: 00250+4.3.2.2;MetaCyc: PWY-6123;MetaCyc: PWY-7219 "Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis I";"Adenosine ribonucleotides de novo biosynthesis" XP_037297187.1 3 Reactome: R-HSA-6787639;Reactome: R-HSA-5619078;Reactome: R-HSA-727802 "GDP-fucose biosynthesis";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)";"Transport of nucleotide sugars" XP_037303193.1 15 Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-2559580;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Oncogene Induced Senescence";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Oxidative Stress Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity" XP_030030593.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_030028191.2 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_030034978.1 2 Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286 "Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism" XP_030035262.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_037295485.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_030025800.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_037300875.1 3 KEGG: 00970+6.1.1.4;Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_030020134.2 5 Reactome: R-HSA-191273;Reactome: R-HSA-2426168;MetaCyc: PWY-922;KEGG: 00900+2.7.4.2;MetaCyc: PWY-7391 "Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)" XP_037293955.1 6 Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450604 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA" XP_030030224.1 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" XP_030022621.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037295578.1 10 KEGG: 05165+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 05163+2.7.1.153;KEGG: 04070+2.7.1.153;KEGG: 04150+2.7.1.153;MetaCyc: PWY-6352;Reactome: R-HSA-9027276;KEGG: 05170+2.7.1.153;KEGG: 00562+2.7.1.153;KEGG: 04151+2.7.1.153 "Human papillomavirus infection";"Synthesis of PIPs at the plasma membrane";"Human cytomegalovirus infection";"Phosphatidylinositol signaling system";"mTOR signaling pathway";"3-phosphoinositide biosynthesis";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human immunodeficiency virus 1 infection";"Inositol phosphate metabolism";"PI3K-Akt signaling pathway" XP_037302674.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_030023407.1 5 MetaCyc: PWY-8060;Reactome: R-HSA-71336;MetaCyc: PWY-7180;Reactome: R-HSA-6798695;KEGG: 00030+4.1.2.4 "2-deoxy-D-ribose degradation I";"Pentose phosphate pathway";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Neutrophil degranulation";"Pentose phosphate pathway" XP_030024615.2 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_030029874.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_037295999.1 4 Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis" XP_037298069.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_030029824.2 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_030020532.1 9 Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-167161 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation" XP_030030676.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037300410.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037293300.1 1 Reactome: R-HSA-975578 "Reactions specific to the complex N-glycan synthesis pathway" XP_030036012.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_030026426.1 4 MetaCyc: PWY-6483;Reactome: R-HSA-1660662;MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23 "Ceramide degradation (generic)";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism" XP_030037347.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037294986.1 5 Reactome: R-HSA-3108214;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-5221030;Reactome: R-HSA-110357 "SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1" XP_030040197.2 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_037298810.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" XP_030020266.2 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037302153.1 3 KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221 "Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis" XP_030036368.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_030028908.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030031441.2 14 MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-6598;Reactome: R-HSA-75876 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs" XP_037301248.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7724 "Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_037299122.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_030038422.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72695 "Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex" XP_037292359.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_030035263.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_037299904.1 2 MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24 "Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis" XP_037293671.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_030031432.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037297258.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037300049.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_030022061.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_037299989.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_037303645.1 1 Reactome: R-HSA-6804760 "Regulation of TP53 Activity through Methylation" XP_037293971.1 4 MetaCyc: PWY-7887;KEGG: 00790+2.8.1.12;MetaCyc: PWY-6823;Reactome: R-HSA-947581 "Protein SAMPylation and SAMP-mediated thiolation";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_030030675.1 7 Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724 "mTOR signalling";"mTORC1-mediated signalling";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription" XP_030038072.2 2 Reactome: R-HSA-1799339;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation" XP_030021525.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"(9Z)-tricosene biosynthesis" XP_030021312.2 9 MetaCyc: PWY-5265;Reactome: R-HSA-5633231;KEGG: 00510+2.4.1.141;MetaCyc: PWY-6470;KEGG: 00550+2.4.1.227;Reactome: R-HSA-446193;MetaCyc: PWY-6385;MetaCyc: PWY-6471;KEGG: 00513+2.4.1.141 "Peptidoglycan biosynthesis II (staphylococci)";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Various types of N-glycan biosynthesis" XP_030031503.1 14 Reactome: R-HSA-5651801;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-5655862;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400 "PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Dual Incision in GG-NER" XP_037297250.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_030038560.2 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_030021423.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_030033673.1 2 Reactome: R-HSA-389957;Reactome: R-HSA-8953750 "Prefoldin mediated transfer of substrate to CCT/TriC";"Transcriptional Regulation by E2F6" XP_030021006.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_030028370.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_030034295.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_030021007.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_037293080.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_030031294.2 7 Reactome: R-HSA-389661;Reactome: R-HSA-204174;KEGG: 00010+1.2.4.1;KEGG: 00020+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-70268;KEGG: 00620+1.2.4.1 "Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Pyruvate metabolism" XP_030035448.2 1 Reactome: R-HSA-8874211 "CREB3 factors activate genes" XP_030028984.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_030040899.2 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_037301337.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_030036490.2 8 KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"Thermogenesis";"Human cytomegalovirus infection" XP_030036886.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037292289.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_030023885.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_030038457.2 14 MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7619 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis" XP_037297835.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037295577.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_030023268.2 9 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway" XP_037297930.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_030021670.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030025048.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-4341670;Reactome: R-HSA-4085001;Reactome: R-HSA-1660662 "Neutrophil degranulation";"MHC class II antigen presentation";"Defective NEU1 causes sialidosis";"Sialic acid metabolism";"Glycosphingolipid metabolism" XP_030034445.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_030030171.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-192823 "Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation" XP_030030643.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339 "Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane" XP_030025814.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030033397.2 4 KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3 "Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_030023823.2 6 MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290;Reactome: R-HSA-5083632;Reactome: R-HSA-913709 "Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins" XP_030023766.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012 "L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_037298036.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_030022271.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037298265.1 8 Reactome: R-HSA-438066;MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736 "Unblocking of NMDA receptors, glutamate binding and activation";"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors" XP_030030202.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_037303445.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-6807505;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"RNA polymerase II transcribes snRNA genes";"Protein ubiquitination" XP_037292638.1 6 Reactome: R-HSA-6803205;Reactome: R-HSA-139915;Reactome: R-HSA-6804759;Reactome: R-HSA-6803211;Reactome: R-HSA-6803204;Reactome: R-HSA-6803207 "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Caspase Activators and Caspases" XP_030027990.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling" XP_030035751.1 13 MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52 "Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series" XP_037292954.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_030026837.2 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_037300781.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_030027144.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_030027387.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037294633.1 2 MetaCyc: PWY-7533;Reactome: R-HSA-1268020 "Gliotoxin biosynthesis";"Mitochondrial protein import" XP_030022266.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030029916.1 5 Reactome: R-HSA-75109;KEGG: 00073+2.3.1.20;Reactome: R-HSA-1482883;Reactome: R-HSA-6798695;KEGG: 00561+2.3.1.20 "Triglyceride biosynthesis";"Cutin, suberine and wax biosynthesis";"Acyl chain remodeling of DAG and TAG";"Neutrophil degranulation";"Glycerolipid metabolism" XP_030027355.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037293048.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_030030900.1 4 Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48 "Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Drug metabolism - other enzymes" XP_037300619.1 2 KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019 "Pyrimidine metabolism";"Pseudouridine degradation" XP_030021477.1 5 Reactome: R-HSA-1660499;Reactome: R-HSA-1445148;Reactome: R-HSA-6798695;Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "Synthesis of PIPs at the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Neutrophil degranulation";"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_030023575.2 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_037293438.1 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_037299997.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_030022752.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037292941.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-5620912 "AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane" XP_030022790.1 3 Reactome: R-HSA-9609523;Reactome: R-HSA-1236974;Reactome: R-HSA-1799339 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane" XP_030039289.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030034272.2 7 Reactome: R-HSA-389661;Reactome: R-HSA-71403;KEGG: 00380+2.3.1.61;Reactome: R-HSA-71064;KEGG: 00020+2.3.1.61;MetaCyc: PWY-5084;KEGG: 00310+2.3.1.61 "Glyoxylate metabolism and glycine degradation";"Citric acid cycle (TCA cycle)";"Tryptophan metabolism";"Lysine catabolism";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation" XP_030022605.1 56 Reactome: R-HSA-9020702;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-5362768;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-8939902;Reactome: R-HSA-69601;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-8939236;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-174154;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-349425;Reactome: R-HSA-5607761 "Interleukin-1 signaling";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Regulation of RUNX2 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling" XP_037299994.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_030031330.1 12 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-141444 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Aggrephagy";"HCMV Early Events";"Mitotic Prometaphase";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_037292611.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_030019732.1 13 Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-5674400;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-5218920;Reactome: R-HSA-5628897;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-8943724;Reactome: R-HSA-1257604;Reactome: R-HSA-1632852 "HSF1-dependent transactivation";"mTORC1-mediated signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"VEGFR2 mediated vascular permeability";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"Regulation of PTEN gene transcription";"PIP3 activates AKT signaling";"Macroautophagy" XP_030034467.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_030022146.1 4 MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943 "Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_030032313.2 13 MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902 "Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"CS/DS degradation";"Other glycan degradation";"Chitin degradation II (Vibrio)" XP_037302926.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037293598.1 5 Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-75105;Reactome: R-HSA-9029558;Reactome: R-HSA-199220 "Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism" XP_030023063.1 13 Reactome: R-HSA-71403;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5538;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-7384;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-5913 "Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"Pyruvate fermentation to acetate V";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)" XP_030035851.1 14 Reactome: R-HSA-71403;MetaCyc: PWY-3781;KEGG: 00020+1.3.5.1;MetaCyc: PWY-6728;KEGG: 00650+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-561;KEGG: 00720+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-4302;MetaCyc: PWY-6969;MetaCyc: PWY-7254;KEGG: 00190+1.3.5.1;MetaCyc: PWY-7279 "Citric acid cycle (TCA cycle)";"Aerobic respiration I (cytochrome c)";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Butanoate metabolism";"Respiratory electron transport";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle VII (acetate-producers)";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)" XP_037299555.1 14 MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199 "Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Fatty acid elongation" XP_037301120.1 17 Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-174048 "Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B" XP_037294166.1 13 KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613;KEGG: 00720+6.3.4.3;MetaCyc: PWY-3841;MetaCyc: PWY-7909;KEGG: 00670+6.3.4.3;MetaCyc: PWY-2161;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;MetaCyc: PWY-1722;MetaCyc: PWY-5030;MetaCyc: PWY-5497 "Carbon fixation pathways in prokaryotes";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)";"Formaldehyde oxidation VII (THF pathway)";"One carbon pool by folate";"Folate polyglutamylation";"Folate transformations I";"One carbon pool by folate";"Metabolism of folate and pterines";"Formate assimilation into 5,10-methylenetetrahydrofolate";"L-histidine degradation III";"Purine nucleobases degradation II (anaerobic)" XP_037298818.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_030035148.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_030023681.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_030031877.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_037301720.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_030036968.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706 "Eukaryotic Translation Termination";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037295387.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_030036143.1 2 Reactome: R-HSA-9033500;Reactome: R-HSA-9033241 "TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import" XP_037300219.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037297530.1 6 KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;MetaCyc: PWY-7039 "Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule" XP_037292890.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_030027464.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_030022147.1 3 Reactome: R-HSA-901042;Reactome: R-HSA-1236974;Reactome: R-HSA-983170 "Calnexin/calreticulin cycle";"ER-Phagosome pathway";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" XP_030040444.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_037302960.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037296110.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_037301144.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_030036085.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030031429.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_030033503.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_030029387.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Association of TriC/CCT with target proteins during biosynthesis";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_030021036.1 8 Reactome: R-HSA-6804757;Reactome: R-HSA-5689880;Reactome: R-HSA-6782210;Reactome: R-HSA-8866652;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-8948747;Reactome: R-HSA-6782135 "Regulation of TP53 Degradation";"Ub-specific processing proteases";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Regulation of PTEN localization";"Dual incision in TC-NER" XP_030023175.1 3 Reactome: R-HSA-6783310;Reactome: R-HSA-110314;Reactome: R-HSA-5689880 "Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex";"Ub-specific processing proteases" XP_030030875.2 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_037294411.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606 "NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_030034751.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037302287.1 83 Reactome: R-HSA-2871809;Reactome: R-HSA-1839117;Reactome: R-HSA-180336;Reactome: R-HSA-2219530;Reactome: R-HSA-167044;Reactome: R-HSA-983695;Reactome: R-HSA-186763;Reactome: R-HSA-9664565;Reactome: R-HSA-9607240;Reactome: R-HSA-8853338;Reactome: R-HSA-109704;Reactome: R-HSA-1250347;Reactome: R-HSA-2871796;Reactome: R-HSA-5654733;Reactome: R-HSA-5654689;Reactome: R-HSA-5654706;Reactome: R-HSA-5654719;Reactome: R-HSA-6807004;Reactome: R-HSA-5654693;Reactome: R-HSA-2424491;Reactome: R-HSA-1433557;Reactome: R-HSA-9028335;Reactome: R-HSA-5654727;Reactome: R-HSA-9634285;Reactome: R-HSA-8983432;Reactome: R-HSA-1295596;Reactome: R-HSA-5673001;Reactome: R-HSA-8856828;Reactome: R-HSA-912631;Reactome: R-HSA-5654712;Reactome: R-HSA-8851805;Reactome: R-HSA-5663213;Reactome: R-HSA-180292;Reactome: R-HSA-5655302;Reactome: R-HSA-512988;Reactome: R-HSA-8856825;Reactome: R-HSA-112412;Reactome: R-HSA-8853334;Reactome: R-HSA-9028731;Reactome: R-HSA-1433559;Reactome: R-HSA-5654710;Reactome: R-HSA-1250196;Reactome: R-HSA-210993;Reactome: R-HSA-9026519;Reactome: R-HSA-912526;Reactome: R-HSA-8851907;Reactome: R-HSA-5655291;Reactome: R-HSA-5654726;Reactome: R-HSA-1963642;Reactome: R-HSA-2428933;Reactome: R-HSA-5654700;Reactome: R-HSA-1236382;Reactome: R-HSA-9034864;Reactome: R-HSA-2029482;Reactome: R-HSA-5654704;Reactome: R-HSA-8853659;Reactome: R-HSA-5654688;Reactome: R-HSA-389359;Reactome: R-HSA-5654720;Reactome: R-HSA-375165;Reactome: R-HSA-5637810;Reactome: R-HSA-354194;Reactome: R-HSA-1963640;Reactome: R-HSA-1257604;Reactome: R-HSA-5654732;Reactome: R-HSA-9027284;Reactome: R-HSA-8875656;Reactome: R-HSA-6811558;Reactome: R-HSA-9645135;Reactome: R-HSA-74749;Reactome: R-HSA-2179392;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-2730905;Reactome: R-HSA-5655253;Reactome: R-HSA-5654699;Reactome: R-HSA-179812;Reactome: R-HSA-388841;Reactome: R-HSA-8875555;Reactome: R-HSA-8865999;Reactome: R-HSA-391160;Reactome: R-HSA-74751;Reactome: R-HSA-5654695 "FCERI mediated Ca+2 mobilization";"Signaling by cytosolic FGFR1 fusion mutants";"SHC1 events in EGFR signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signalling to RAS";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Downstream signal transduction";"Signaling by ERBB2 KD Mutants";"FLT3 Signaling";"Signaling by FGFR3 point mutants in cancer";"PI3K Cascade";"SHC1 events in ERBB4 signaling";"FCERI mediated MAPK activation";"Negative regulation of FGFR4 signaling";"PI-3K cascade:FGFR1";"FRS-mediated FGFR3 signaling";"SHC-mediated cascade:FGFR4";"Negative regulation of MET activity";"FRS-mediated FGFR1 signaling";"DAP12 signaling";"Signaling by SCF-KIT";"Activated NTRK2 signals through PI3K";"Negative regulation of FGFR2 signaling";"Constitutive Signaling by Overexpressed ERBB2";"Interleukin-15 signaling";"Spry regulation of FGF signaling";"RAF/MAP kinase cascade";"Clathrin-mediated endocytosis";"Regulation of signaling by CBL";"FRS-mediated FGFR4 signaling";"MET activates RAS signaling";"RHO GTPases Activate WASPs and WAVEs";"GAB1 signalosome";"Signaling by FGFR1 in disease";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Cargo recognition for clathrin-mediated endocytosis";"SOS-mediated signalling";"Signaling by FGFR3 fusions in cancer";"Activated NTRK2 signals through FRS2 and FRS3";"Regulation of KIT signaling";"PI-3K cascade:FGFR3";"SHC1 events in ERBB2 signaling";"Tie2 Signaling";"Activated NTRK2 signals through RAS";"Interleukin receptor SHC signaling";"MET activates PI3K/AKT signaling";"Signaling by FGFR4 in disease";"Negative regulation of FGFR1 signaling";"PI3K events in ERBB2 signaling";"SHC-related events triggered by IGF1R";"FRS-mediated FGFR2 signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Activated NTRK3 signals through RAS";"Regulation of actin dynamics for phagocytic cup formation";"SHC-mediated cascade:FGFR3";"RET signaling";"SHC-mediated cascade:FGFR1";"CD28 dependent Vav1 pathway";"PI-3K cascade:FGFR4";"NCAM signaling for neurite out-growth";"Constitutive Signaling by EGFRvIII";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"GRB2 events in ERBB2 signaling";"PIP3 activates AKT signaling";"Negative regulation of FGFR3 signaling";"Erythropoietin activates RAS";"MET receptor recycling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"STAT5 Activation";"Signal attenuation";"EGFR Transactivation by Gastrin";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Role of LAT2/NTAL/LAB on calcium mobilization";"Signaling by FGFR2 in disease";"SHC-mediated cascade:FGFR2";"GRB2 events in EGFR signaling";"Costimulation by the CD28 family";"MET activates RAP1 and RAC1";"MET activates PTPN11";"Signal regulatory protein family interactions";"Insulin receptor signalling cascade";"PI-3K cascade:FGFR2" XP_030035514.2 31 KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6799;MetaCyc: PWY-7664;MetaCyc: PWY-4381;Reactome: R-HSA-163765;MetaCyc: PWY-6519;MetaCyc: PWY-5367;MetaCyc: PWY-6282;Reactome: R-HSA-9029558;MetaCyc: PWY-7723;MetaCyc: PWY-8049;MetaCyc: PWY-6113;MetaCyc: PWY-5966-1;MetaCyc: PWY-7746;MetaCyc: PWY-8012;MetaCyc: PWY-8047;Reactome: R-HSA-2426168;MetaCyc: PWYG-321;MetaCyc: PWY-5989;MetaCyc: PWY-5973;MetaCyc: PWY-7858;Reactome: R-HSA-75105;MetaCyc: PWY-5142;MetaCyc: PWY-7388;MetaCyc: PWY-5971;MetaCyc: PWY-5994;MetaCyc: PWY-5147;Reactome: R-HSA-199220;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5366;MetaCyc: PWY-7663 "Biotin metabolism";"Fatty acid biosynthesis initiation (plant mitochondria)";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (bacteria and plants)";"ChREBP activates metabolic gene expression";"8-amino-7-oxononanoate biosynthesis I";"Petroselinate biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Bacterial bioluminescence";"Pederin biosynthesis";"Superpathway of mycolate biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Mycobacterial sulfolipid biosynthesis";"Mupirocin biosynthesis";"Bryostatin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"";"Stearate biosynthesis II (bacteria and plants)";"Cis-vaccenate biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Fatty acyl-CoA biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Oleate biosynthesis I (plants)";"Vitamin B5 (pantothenate) metabolism";"Fatty acid biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Gondoate biosynthesis (anaerobic)" XP_037298259.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_030024783.1 5 MetaCyc: PWY-5189;KEGG: 00860+2.3.1.37;Reactome: R-HSA-189451;KEGG: 00260+2.3.1.37;MetaCyc: PWY-7536 "Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Glycine, serine and threonine metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis" XP_030035264.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_037299995.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_037299436.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037294097.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_037293941.1 4 MetaCyc: PWY-7511;Reactome: R-HSA-975144;Reactome: R-HSA-9020702;Reactome: R-HSA-937039 "Protein ubiquitination";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling";"IRAK1 recruits IKK complex" XP_030033207.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037294409.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606 "Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_037295013.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_030022640.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-156827 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_030027143.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_030035983.1 3 Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (i) signalling events";"G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_030037273.1 6 Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-380994 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_030029589.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037296669.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_030029630.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_037300635.1 6 KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039 "Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule" XP_037303078.1 7 KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;MetaCyc: PWY-6367;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052 "Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis" XP_037296896.1 4 KEGG: 00040+2.7.1.17;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-5661270 "Pentose and glucuronate interconversions";"Glycerol degradation I";"Glycerolipid metabolism";"Formation of xylulose-5-phosphate" XP_037293556.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_030027000.1 57 Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-5362768;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-174154;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-1234176;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553 "Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Vpu mediated degradation of CD4";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs" XP_037297968.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-9010553 "Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs" XP_037302866.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037293372.1 4 Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001 "NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade" XP_030032266.2 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_030021923.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_037294265.1 4 Reactome: R-HSA-5660862;Reactome: R-HSA-210991;Reactome: R-HSA-71240;Reactome: R-HSA-352230 "Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Basigin interactions";"Tryptophan catabolism";"Amino acid transport across the plasma membrane" XP_030023044.1 8 Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68827 "Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex" XP_037298554.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" YP_001650749.1 7 MetaCyc: PWY-6692;MetaCyc: PWY-5083;MetaCyc: PWY-4302;Reactome: R-HSA-611105;Reactome: R-HSA-6799198;KEGG: 00190+7.1.1.2;MetaCyc: PWY-3781 "Fe(II) oxidation";"NAD/NADH phosphorylation and dephosphorylation";"Aerobic respiration III (alternative oxidase pathway)";"Respiratory electron transport";"Complex I biogenesis";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)" XP_030027676.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_037297409.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2 "VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway" XP_030028944.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_030020770.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037295465.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_030041150.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037296594.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_030023880.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_037295527.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73776 "Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape" XP_037300977.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_030041064.2 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_030023798.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_030038036.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-77595 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs" XP_030023097.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_037300255.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_030027545.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_030023724.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947 "Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription" XP_037295110.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-8876198 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_030021716.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226 "Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_030040706.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_030030179.2 2 MetaCyc: PWY-7511;Reactome: R-HSA-6798695 "Protein ubiquitination";"Neutrophil degranulation" XP_030036171.2 1 Reactome: R-HSA-8876725 "Protein methylation" XP_037299430.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037298119.1 2 Reactome: R-HSA-6811436;Reactome: R-HSA-8876198 "COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_037294288.1 10 Reactome: R-HSA-6798695;Reactome: R-HSA-2160916;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-2206292;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23 "Neutrophil degranulation";"Hyaluronan uptake and degradation";"Galactose metabolism";"Sphingolipid metabolism";"HS-GAG degradation";"MPS VII - Sly syndrome";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Other glycan degradation" XP_037301313.1 17 Reactome: R-HSA-5685942;Reactome: R-HSA-69166;Reactome: R-HSA-5358606;Reactome: R-HSA-5696397;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5358565;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-69183;Reactome: R-HSA-174437;Reactome: R-HSA-5651801;Reactome: R-HSA-174414;Reactome: R-HSA-174417;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-174411 "HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate from the C-strand";"PCNA-Dependent Long Patch Base Excision Repair";"Processive synthesis on the C-strand of the telomere";"Telomere C-strand (Lagging Strand) Synthesis";"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere" XP_037302552.1 1 Reactome: R-HSA-2565942 "Regulation of PLK1 Activity at G2/M Transition" XP_030029343.1 8 Reactome: R-HSA-4608870;Reactome: R-HSA-4086398;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900;Reactome: R-HSA-373080;Reactome: R-HSA-5340588;Reactome: R-HSA-8856825;Reactome: R-HSA-4641263 "Asymmetric localization of PCP proteins";"Ca2+ pathway";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Class B/2 (Secretin family receptors)";"RNF mutants show enhanced WNT signaling and proliferation";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of FZD by ubiquitination" XP_030025186.2 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037299134.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_037292599.1 12 KEGG: 00051+4.1.2.13;MetaCyc: PWY-5484;MetaCyc: PWY-7385;MetaCyc: PWY-6142;MetaCyc: PWY-1861;KEGG: 00710+4.1.2.13;KEGG: 00010+4.1.2.13;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1042;Reactome: R-HSA-70171;Reactome: R-HSA-70263;KEGG: 00680+4.1.2.13 "Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Glycolysis";"Gluconeogenesis";"Methane metabolism" XP_030036318.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_030031325.1 12 Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"HCMV Early Events";"Aggrephagy";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_030026800.2 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_037297912.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037303591.1 8 Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852 "Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Neutrophil degranulation";"mTOR signalling";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Macroautophagy" XP_037299902.1 2 MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24 "Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis" XP_030034274.2 7 Reactome: R-HSA-389661;Reactome: R-HSA-71403;Reactome: R-HSA-71064;KEGG: 00380+2.3.1.61;MetaCyc: PWY-5084;KEGG: 00020+2.3.1.61;KEGG: 00310+2.3.1.61 "Glyoxylate metabolism and glycine degradation";"Citric acid cycle (TCA cycle)";"Lysine catabolism";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Lysine degradation" XP_030040762.1 18 MetaCyc: PWY-7417;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;Reactome: R-HSA-1482925;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8051;Reactome: R-HSA-1482922;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-8053;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;KEGG: 00591+3.1.1.4 "Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Acyl chain remodelling of PG";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Acyl chain remodelling of PI";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PS";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Synthesis of PA";"Linoleic acid metabolism" XP_030023549.2 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_030035513.2 31 MetaCyc: PWY-5971;MetaCyc: PWY-5994;MetaCyc: PWY-7388;Reactome: R-HSA-199220;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5366;MetaCyc: PWY-7663;MetaCyc: PWY-5147;MetaCyc: PWYG-321;Reactome: R-HSA-2426168;MetaCyc: PWY-5142;MetaCyc: PWY-5989;MetaCyc: PWY-5973;Reactome: R-HSA-75105;MetaCyc: PWY-7858;MetaCyc: PWY-7746;MetaCyc: PWY-6113;MetaCyc: PWY-5966-1;MetaCyc: PWY-8012;MetaCyc: PWY-8047;MetaCyc: PWY-4381;MetaCyc: PWY-7664;MetaCyc: PWY-6799;Reactome: R-HSA-163765;MetaCyc: PWY-6519;MetaCyc: PWY-6282;MetaCyc: PWY-5367;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8049;MetaCyc: PWY-7723;Reactome: R-HSA-9029558 "Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Vitamin B5 (pantothenate) metabolism";"Fatty acid biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Gondoate biosynthesis (anaerobic)";"Oleate biosynthesis I (plants)";"";"Activation of gene expression by SREBF (SREBP)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Stearate biosynthesis II (bacteria and plants)";"Cis-vaccenate biosynthesis";"Fatty acyl-CoA biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Mycobacterial sulfolipid biosynthesis";"Superpathway of mycolate biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Mupirocin biosynthesis";"Bryostatin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (plant mitochondria)";"ChREBP activates metabolic gene expression";"8-amino-7-oxononanoate biosynthesis I";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Petroselinate biosynthesis";"Biotin metabolism";"Pederin biosynthesis";"Bacterial bioluminescence";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis" XP_030032449.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037295290.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037301456.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" XP_030032394.2 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_037295558.1 20 KEGG: 00071+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7007;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-6920;MetaCyc: PWY-7858;MetaCyc: PWY-7854;Reactome: R-HSA-9033241;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6;MetaCyc: PWY-5136;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7288;MetaCyc: PWY-7291;MetaCyc: PWY-735 "Fatty acid degradation";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Methyl ketone biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis" XP_030022618.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8949664 "Mitochondrial protein import";"Processing of SMDT1" XP_037295692.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037296994.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_037298252.1 12 Reactome: R-HSA-9617324;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-447038;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;MetaCyc: PWY-7221;Reactome: R-HSA-399719;Reactome: R-HSA-451308 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"NrCAM interactions";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Guanosine ribonucleotides de novo biosynthesis";"Trafficking of AMPA receptors";"Activation of Ca-permeable Kainate Receptor" XP_030025987.1 4 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling" XP_030038548.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_037297909.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_030039861.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_030024719.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030038701.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_030041413.1 8 Reactome: R-HSA-2426168;MetaCyc: PWY-922;MetaCyc: PWY-7391;MetaCyc: PWY-7524;KEGG: 00900+1.1.1.34;Reactome: R-HSA-191273;Reactome: R-HSA-1989781;MetaCyc: PWY-6174 "Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"PPARA activates gene expression";"Mevalonate pathway II (archaea)" XP_037292695.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037302754.1 19 MetaCyc: PWY-6920;MetaCyc: PWY-7338;MetaCyc: PWY-7858;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7340;MetaCyc: PWY-7007;MetaCyc: PWY-6837;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7606;MetaCyc: PWY-5136;KEGG: 00640+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7291;MetaCyc: PWY-7288 "6-gingerol analog biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation";"10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"Propanoyl-coa degradation II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoate metabolism";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)" XP_030028860.1 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_030025161.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_030027964.1 5 Reactome: R-HSA-5617472;Reactome: R-HSA-3769402;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-201722 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex" XP_037296158.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030024242.2 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_030025850.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_030030006.1 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_037298630.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_030026592.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_037294978.1 5 Reactome: R-HSA-110357;Reactome: R-HSA-5221030;Reactome: R-HSA-3108214;Reactome: R-HSA-110328;Reactome: R-HSA-110329 "Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA";"SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine" XP_030030536.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_030021674.1 24 Reactome: R-HSA-428930;Reactome: R-HSA-432040;Reactome: R-HSA-202040;Reactome: R-HSA-416476;Reactome: R-HSA-400042;Reactome: R-HSA-381676;Reactome: R-HSA-4086398;Reactome: R-HSA-8964616;Reactome: R-HSA-418597;Reactome: R-HSA-500657;Reactome: R-HSA-420092;Reactome: R-HSA-456926;Reactome: R-HSA-418217;Reactome: R-HSA-392170;Reactome: R-HSA-416482;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-8964315;Reactome: R-HSA-418555;Reactome: R-HSA-9009391;Reactome: R-HSA-392451;Reactome: R-HSA-392851;Reactome: R-HSA-163359;Reactome: R-HSA-418592 "Thromboxane signalling through TP receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"G-protein activation";"G alpha (q) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway";"G beta:gamma signalling through CDC42";"G alpha (z) signalling events";"Presynaptic function of Kainate receptors";"Glucagon-type ligand receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 12";"G alpha (12/13) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"G beta:gamma signalling through BTK";"G alpha (s) signalling events";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through PI3Kgamma";"Prostacyclin signalling through prostacyclin receptor";"Glucagon signaling in metabolic regulation";"ADP signalling through P2Y purinoceptor 1" XP_037295011.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_037297606.1 14 Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5656121 "Translesion synthesis by POLK";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Translesion synthesis by POLI" XP_037301915.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_037300634.1 3 Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-73856 "SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination" XP_037298515.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_030034157.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037302229.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037297654.1 4 MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7;Reactome: R-HSA-947581;Reactome: R-HSA-1362409 "[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism";"Molybdenum cofactor biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis" XP_030028542.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_037296593.1 5 Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-3214841;Reactome: R-HSA-3769402;Reactome: R-HSA-5617472 "Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines";"Deactivation of the beta-catenin transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_037299996.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_030024697.2 2 Reactome: R-HSA-163282;Reactome: R-HSA-2151201 "Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis" XP_030031502.1 14 Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-110312;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862 "Translesion synthesis by POLI";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK" XP_037293346.1 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" XP_030028507.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_037303641.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_030033315.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037300573.1 7 Reactome: R-HSA-381070;Reactome: R-HSA-3371453;Reactome: R-HSA-381183;Reactome: R-HSA-381042;Reactome: R-HSA-381033;Reactome: R-HSA-983170;Reactome: R-HSA-114608 "IRE1alpha activates chaperones";"Regulation of HSF1-mediated heat shock response";"ATF6 (ATF6-alpha) activates chaperone genes";"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperones";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Platelet degranulation" XP_037294650.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_030031880.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_030026566.2 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_037295375.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030029083.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_037293519.1 16 Reactome: R-HSA-9018519;Reactome: R-HSA-3214847;Reactome: R-HSA-5693554;Reactome: R-HSA-5693548;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-2559586;Reactome: R-HSA-201722;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565 "Estrogen-dependent gene expression";"HATs acetylate histones";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Sensing of DNA Double Strand Breaks";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"DNA Damage/Telomere Stress Induced Senescence";"Formation of the beta-catenin:TCF transactivating complex";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_037292574.1 18 KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482801;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;MetaCyc: PWY-6803;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-8051;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482925 "Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PS";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Synthesis of PA";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PI";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PG" XP_037296499.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling" XP_037295836.1 5 MetaCyc: PWY-7268;MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism" XP_037292275.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037298884.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030034885.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037299737.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_030035117.2 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_030024493.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-110320 "Ub-specific processing proteases";"Translesion Synthesis by POLH" XP_037292200.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037295207.1 2 Reactome: R-HSA-5685938;Reactome: R-HSA-3108214 "HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins" XP_030036930.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_030029106.1 2 KEGG: 00970+6.1.1.9;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_037299738.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037294836.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_030020163.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_030027797.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030032558.1 6 Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-176974 "Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Unwinding of DNA" XP_030040476.1 14 KEGG: 00190+1.3.5.1;MetaCyc: PWY-7254;MetaCyc: PWY-7279;MetaCyc: PWY-6969;MetaCyc: PWY-4302;MetaCyc: PWY-5690;KEGG: 00720+1.3.5.1;MetaCyc: PWY-561;Reactome: R-HSA-611105;KEGG: 00650+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-6728;MetaCyc: PWY-3781;Reactome: R-HSA-71403 "Oxidative phosphorylation";"TCA cycle VII (acetate-producers)";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"Respiratory electron transport";"Butanoate metabolism";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Aerobic respiration I (cytochrome c)";"Citric acid cycle (TCA cycle)" XP_030023540.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_030023308.2 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_030031621.1 14 Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-113418 "Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex" XP_030022810.2 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_030032240.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_030026616.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_030021484.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_030026614.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_030024150.2 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_030029079.2 6 MetaCyc: PWY-6722;MetaCyc: PWY-4381;MetaCyc: PWY-5743;Reactome: R-HSA-196780;MetaCyc: PWY-5789;MetaCyc: PWY-5744 "Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate cycle";"Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation" XP_030023058.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030040942.1 6 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)" XP_030041090.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_030025134.2 15 Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128 "Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling" XP_030029247.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_037303153.1 6 Reactome: R-HSA-77588;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-191859;Reactome: R-HSA-111367 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"snRNP Assembly";"SLBP independent Processing of Histone Pre-mRNAs" XP_030039698.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030027825.1 2 Reactome: R-HSA-3214815;Reactome: R-HSA-427413 "HDACs deacetylate histones";"NoRC negatively regulates rRNA expression" XP_030028560.2 4 Reactome: R-HSA-9615017;Reactome: R-HSA-9614399;Reactome: R-HSA-5674400;Reactome: R-HSA-198693 "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of localization of FOXO transcription factors";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the nucleus" XP_037303402.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-171319 "HATs acetylate histones";"Telomere Extension By Telomerase" XP_037303296.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_030036302.2 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_037299520.1 3 Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646 "Defective ACY1 causes encephalopathy";"Arginine biosynthesis";"Aflatoxin activation and detoxification" XP_037292285.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_030020938.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" XP_030035720.2 4 MetaCyc: PWY-7807;Reactome: R-HSA-71737;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805 "Glyphosate degradation III";"Pyrophosphate hydrolysis";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation" XP_037297242.1 3 Reactome: R-HSA-5626978;Reactome: R-HSA-1660662;Reactome: R-HSA-193681 "TNFR1-mediated ceramide production";"Glycosphingolipid metabolism";"Ceramide signalling" XP_030020364.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_030025376.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-6798695 "Glycosphingolipid metabolism";"Neutrophil degranulation" XP_037300602.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_037303410.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_037294408.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription" XP_037297588.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase" XP_037302175.1 5 MetaCyc: PWY-5083;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-7269 "NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_030025114.1 3 Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395 "Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER" XP_030040866.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_030025804.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030025809.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030032414.2 5 Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_030032752.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037296161.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030033447.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_030036762.2 56 Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-8939236;Reactome: R-HSA-8939902;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-5607764;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-174084 "Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Vpu mediated degradation of CD4";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX2 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CLEC7A (Dectin-1) signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Degradation of DVL";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C" XP_037297643.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_037293905.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_030040917.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_030040702.1 40 Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-72203;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-5578749;Reactome: R-HSA-6781827;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-5601884;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-167162;Reactome: R-HSA-8851708;Reactome: R-HSA-72163;Reactome: R-HSA-167243;Reactome: R-HSA-9018519;Reactome: R-HSA-167161;Reactome: R-HSA-72165;Reactome: R-HSA-75953;Reactome: R-HSA-167287;Reactome: R-HSA-6782135;Reactome: R-HSA-167242;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-203927;Reactome: R-HSA-167238;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-168325;Reactome: R-HSA-6803529;Reactome: R-HSA-75955;Reactome: R-HSA-5617472;Reactome: R-HSA-6796648;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-73776 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Processing of Capped Intron-Containing Pre-mRNA";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"Transcriptional regulation by small RNAs";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"PIWI-interacting RNA (piRNA) biogenesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II HIV Promoter Escape";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Major Pathway";"Tat-mediated HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"HIV Transcription Initiation";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation";"HIV elongation arrest and recovery";"Dual incision in TC-NER";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"MicroRNA (miRNA) biogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"Viral Messenger RNA Synthesis";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Promoter Escape" XP_030030459.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-162588 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion" XP_037297424.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_037300529.1 3 MetaCyc: PWY-1801;Reactome: R-HSA-156590;KEGG: 00680+3.1.2.12 "Formaldehyde oxidation II (glutathione-dependent)";"Glutathione conjugation";"Methane metabolism" XP_037293756.1 4 Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-8866654 "RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins" XP_030022739.2 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" XP_030021920.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_037302635.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_030038404.2 5 Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264;MetaCyc: PWY-5381 "Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)" XP_030029673.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-76042 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_037301957.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_030023543.2 6 Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039 "Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule" XP_037302313.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_030032587.2 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_030029402.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_030040876.1 3 KEGG: 00130+1.17.4.4;MetaCyc: PWY-7999;Reactome: R-HSA-6806664 "Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle";"Metabolism of vitamin K" XP_037299988.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_030028262.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_037294475.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" XP_037292189.1 3 Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2 "Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism" XP_030039798.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_030030897.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037300786.1 7 Reactome: R-HSA-6798695;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-264870;Reactome: R-HSA-373753 "Neutrophil degranulation";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Caspase-mediated cleavage of cytoskeletal proteins";"Nephrin family interactions" XP_030027064.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037293915.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_030022700.1 57 Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Hedgehog 'on' state";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases" XP_030029122.1 7 Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-69205 "Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription" XP_030037960.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_030040821.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_030041003.2 3 KEGG: 00330+2.3.1.57;MetaCyc: PWY-0;MetaCyc: PWY-6117 "Arginine and proline metabolism";"Putrescine degradation III";"Spermine and spermidine degradation I" XP_030021165.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_030027145.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_030029911.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_030027855.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_037293555.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_030024782.2 4 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_030020776.1 4 Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination" XP_030031132.2 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_037302639.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_037303369.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037296739.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_030021376.2 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_037293942.1 4 Reactome: R-HSA-937039;Reactome: R-HSA-9020702;Reactome: R-HSA-975144;MetaCyc: PWY-7511 "IRAK1 recruits IKK complex";"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Protein ubiquitination" XP_030030259.2 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" XP_030033936.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_037293467.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection" XP_030037166.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037295583.1 10 KEGG: 05170+2.7.1.153;KEGG: 00562+2.7.1.153;KEGG: 04151+2.7.1.153;KEGG: 05165+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 04070+2.7.1.153;KEGG: 05163+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 04150+2.7.1.153;MetaCyc: PWY-6352 "Human immunodeficiency virus 1 infection";"Inositol phosphate metabolism";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Human cytomegalovirus infection";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"mTOR signaling pathway";"3-phosphoinositide biosynthesis" XP_037294713.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_030039290.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_037295154.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037300894.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_037299892.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-3214815 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones" XP_030020069.1 5 Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037298283.1 3 Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007 "Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy" XP_030021956.1 7 Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76066 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_030034875.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_030028422.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_030034350.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823 "Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex" XP_030040946.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_030024996.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037298752.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_030027067.2 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_030040523.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_030027498.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_037298613.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_030032665.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_037295163.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030040613.1 5 Reactome: R-HSA-73614;Reactome: R-HSA-73621;KEGG: 00983+2.4.2.3;MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3 "Pyrimidine salvage";"Pyrimidine catabolism";"Drug metabolism - other enzymes";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism" XP_037293522.1 9 Reactome: R-HSA-416476;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-112043 "G alpha (q) signalling events";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events" XP_037303285.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037302959.1 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_030026707.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037293798.1 1 Reactome: R-HSA-427601 "Multifunctional anion exchangers" XP_037298094.1 3 KEGG: 00600+3.2.1.45;KEGG: 00511+3.2.1.45;Reactome: R-HSA-1660662 "Sphingolipid metabolism";"Other glycan degradation";"Glycosphingolipid metabolism" XP_037301202.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_030025232.1 4 Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814 "Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes" XP_030033062.2 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_030028228.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_030022392.2 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_037293565.1 16 Reactome: R-HSA-2559582;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-2467813 "Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"Separation of Sister Chromatids" XP_037294741.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037295096.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_030027449.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_030024427.2 4 Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_030028914.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_030035674.2 2 Reactome: R-HSA-2564830;Reactome: R-HSA-5693554 "Cytosolic iron-sulfur cluster assembly";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_037293558.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037300205.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_037293487.1 9 Reactome: R-HSA-70263;Reactome: R-HSA-3371599;KEGG: 00020+6.4.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-8086;KEGG: 00620+6.4.1.1;KEGG: 00720+6.4.1.1;MetaCyc: PWY-6146;Reactome: R-HSA-196780 "Gluconeogenesis";"Defective HLCS causes multiple carboxylase deficiency";"Citrate cycle (TCA cycle)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Biotin transport and metabolism" XP_030033989.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030020639.1 52 Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-73772;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-72203;Reactome: R-HSA-167290;Reactome: R-HSA-73863;Reactome: R-HSA-5601884;Reactome: R-HSA-112382;Reactome: R-HSA-5578749;Reactome: R-HSA-6781827;Reactome: R-HSA-427413;Reactome: R-HSA-8851708;Reactome: R-HSA-72163;Reactome: R-HSA-167162;Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-9018519;Reactome: R-HSA-5250924;Reactome: R-HSA-76061;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-72165;Reactome: R-HSA-75953;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-73780;Reactome: R-HSA-6782135;Reactome: R-HSA-73980;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-167242;Reactome: R-HSA-73762;Reactome: R-HSA-168325;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-5617472;Reactome: R-HSA-6803529;Reactome: R-HSA-75955;Reactome: R-HSA-203927;Reactome: R-HSA-167238;Reactome: R-HSA-72086;Reactome: R-HSA-1834949;Reactome: R-HSA-73776;Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-167158 "Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase I Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of HIV elongation";"RNA Polymerase I Transcription Termination";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of RNA Pol II elongation complex";"Transcriptional regulation by small RNAs";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NoRC negatively regulates rRNA expression";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Major Pathway";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Estrogen-dependent gene expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"RNA Polymerase III Chain Elongation";"Dual incision in TC-NER";"RNA Polymerase III Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase I Transcription Initiation";"Viral Messenger RNA Synthesis";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Elongation";"MicroRNA (miRNA) biogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Capping";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex" XP_030035693.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_030040242.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" XP_030019700.1 3 Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3;KEGG: 00680+3.1.3.3 "Serine biosynthesis";"Glycine, serine and threonine metabolism";"Methane metabolism" XP_037292414.1 12 Reactome: R-HSA-177929;Reactome: R-HSA-75893;Reactome: R-HSA-982772;Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-5362798;Reactome: R-HSA-2660826;Reactome: R-HSA-1442490;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-1251985 "Signaling by EGFR";"TNF signaling";"Growth hormone receptor signaling";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Release of Hh-Np from the secreting cell";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Collagen degradation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Nuclear signaling by ERBB4" XP_037300803.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_030029995.2 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_037296890.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_037297591.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_030040313.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_037299400.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030020801.1 26 Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-389960;Reactome: R-HSA-389977;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332 "Kinesins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Recycling pathway of L1";"Formation of tubulin folding intermediates by CCT/TriC";"Post-chaperonin tubulin folding pathway";"Aggrephagy";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Cilium Assembly";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin" XP_030035258.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_037295457.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_030029024.1 4 Reactome: R-HSA-2408557;MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11;Reactome: R-HSA-379716 "Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_037298561.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_037301128.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_030035917.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72706 "Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_030025078.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_030041010.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030028190.2 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037298483.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_030034687.2 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_030040578.2 11 Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-68952;Reactome: R-HSA-110314;Reactome: R-HSA-68962;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-174430;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169 "Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"DNA replication initiation";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Telomere C-strand synthesis initiation";"Dual incision in TC-NER";"Termination of translesion DNA synthesis" XP_037300290.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037303347.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_030019747.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037301200.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_030040688.2 5 Reactome: R-HSA-211945;Reactome: R-HSA-1989781;Reactome: R-HSA-8937144;Reactome: R-HSA-211976;Reactome: R-HSA-211981 "Phase I - Functionalization of compounds";"PPARA activates gene expression";"Aryl hydrocarbon receptor signalling";"Endogenous sterols";"Xenobiotics" XP_030024199.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_030037615.2 1 Reactome: R-HSA-74217 "Purine salvage" XP_030032181.1 6 KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143 "N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis" XP_030021717.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_030020714.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68962 "Switching of origins to a post-replicative state";"Unwinding of DNA";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex" XP_030031295.2 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_030041202.1 11 Reactome: R-HSA-1368108;Reactome: R-HSA-9018519;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-212436;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-383280;Reactome: R-HSA-400206;Reactome: R-HSA-1989781 "BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Estrogen-dependent gene expression";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"Generic Transcription Pathway";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Nuclear Receptor transcription pathway";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression" XP_037297237.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_037300536.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_030036491.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037300883.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_030037585.1 3 Reactome: R-HSA-70268;MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5 "Pyruvate metabolism";"Methylglyoxal degradation I";"Pyruvate metabolism" XP_037301350.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030024619.2 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_037294048.1 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2299718 "Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes" XP_037297925.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_030022610.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_030037750.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-6791226 "mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_030027935.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-194840 "RAB GEFs exchange GTP for GDP on RABs";"Rho GTPase cycle" XP_030030967.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037294080.1 8 Reactome: R-HSA-5083633;Reactome: R-HSA-5173105;MetaCyc: PWY-7922;Reactome: R-HSA-5083629;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921 "Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)" XP_030040540.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_030022380.1 56 Reactome: R-HSA-1234176;Reactome: R-HSA-8939236;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-180585;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-187577 "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Vif-mediated degradation of APOBEC3G";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21" XP_030029471.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037296956.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_037300186.1 13 MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5538;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-5913;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5537 "Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"Pyruvate fermentation to acetate V" XP_030032003.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_037303339.1 8 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-165054 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA" XP_030036708.2 12 Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-1042;KEGG: 00680+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-7385;MetaCyc: PWY-5484;KEGG: 00051+4.1.2.13;KEGG: 00030+4.1.2.13;KEGG: 00010+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-1861 "Gluconeogenesis";"Glycolysis";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" XP_037299564.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_030029488.2 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_037300099.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_030037471.1 3 Reactome: R-HSA-349425;Reactome: R-HSA-8951664;MetaCyc: PWY-7511 "Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"Protein ubiquitination" XP_030021138.1 8 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"Signaling by Hippo";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway" XP_037300080.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030026425.1 4 MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-6483 "Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide degradation (generic)" XP_030030671.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_030023269.1 5 Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-1445148 "RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_037297786.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_030031141.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037302734.1 5 Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-2132295 "Cargo concentration in the ER";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation" XP_030024977.2 1 Reactome: R-HSA-8951664 "Neddylation" XP_030036929.1 12 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9619483;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-5628897;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-380972;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Activation of AMPK downstream of NMDARs";"Human papillomavirus infection";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Metabolic Genes";"PI3K-Akt signaling pathway";"Macroautophagy";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human cytomegalovirus infection" XP_037301055.1 42 Reactome: R-HSA-73772;Reactome: R-HSA-606279;Reactome: R-HSA-69473;Reactome: R-HSA-1912408;Reactome: R-HSA-427389;Reactome: R-HSA-9609690;Reactome: R-HSA-5693571;Reactome: R-HSA-2559582;Reactome: R-HSA-9610379;Reactome: R-HSA-5334118;Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-8936459;Reactome: R-HSA-3214858;Reactome: R-HSA-912446;Reactome: R-HSA-9018519;Reactome: R-HSA-5250924;Reactome: R-HSA-8939236;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-110331;Reactome: R-HSA-110329;Reactome: R-HSA-73728;Reactome: R-HSA-2299718;Reactome: R-HSA-212300;Reactome: R-HSA-9616222;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-3214842;Reactome: R-HSA-2559586;Reactome: R-HSA-201722;Reactome: R-HSA-977225;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-3214841;Reactome: R-HSA-1221632;Reactome: R-HSA-3214815;Reactome: R-HSA-110330;Reactome: R-HSA-4551638;Reactome: R-HSA-3214847;Reactome: R-HSA-110328;Reactome: R-HSA-171306 "RNA Polymerase I Promoter Escape";"Deposition of new CENPA-containing nucleosomes at the centromere";"G2/M DNA damage checkpoint";"Pre-NOTCH Transcription and Translation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HCMV Early Events";"Nonhomologous End-Joining (NHEJ)";"Senescence-Associated Secretory Phenotype (SASP)";"HCMV Late Events";"DNA methylation";"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RMTs methylate histone arginines";"Meiotic recombination";"Estrogen-dependent gene expression";"B-WICH complex positively regulates rRNA expression";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"Cleavage of the damaged purine";"Cleavage of the damaged pyrimidine";"RNA Polymerase I Promoter Opening";"Condensation of Prophase Chromosomes";"PRC2 methylates histones and DNA";"Transcriptional regulation of granulopoiesis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"HDMs demethylate histones";"DNA Damage/Telomere Stress Induced Senescence";"Formation of the beta-catenin:TCF transactivating complex";"Amyloid fiber formation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"PKMTs methylate histone lysines";"Meiotic synapsis";"HDACs deacetylate histones";"Recognition and association of DNA glycosylase with site containing an affected purine";"SUMOylation of chromatin organization proteins";"HATs acetylate histones";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Packaging Of Telomere Ends" XP_030021596.1 3 KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857;Reactome: R-HSA-192456 "Glycerolipid metabolism";"Retinol biosynthesis";"Digestion of dietary lipid" XP_030024940.2 5 KEGG: 00230+3.6.1.6;KEGG: 00240+3.6.1.6;Reactome: R-HSA-6798695;MetaCyc: PWY-7210;MetaCyc: PWY-7185 "Purine metabolism";"Pyrimidine metabolism";"Neutrophil degranulation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP dephosphorylation I" XP_030034607.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_030032021.1 3 MetaCyc: PWY-4361;Reactome: R-HSA-1237112;KEGG: 00270+1.13.11.54 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"Cysteine and methionine metabolism" XP_030040111.2 2 Reactome: R-HSA-162710;KEGG: 00563+3.5.1.89 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_037300491.1 11 KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04926+2.7.11.1;Reactome: R-HSA-450302;Reactome: R-HSA-171007;Reactome: R-HSA-4420097;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"Relaxin signaling pathway";"activated TAK1 mediates p38 MAPK activation";"p38MAPK events";"VEGFA-VEGFR2 Pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_030025318.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_037294450.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_030036392.2 3 Reactome: R-HSA-159740;KEGG: 00130+4.1.1.90;MetaCyc: PWY-7999 "Gamma-carboxylation of protein precursors";"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle" XP_030020727.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_037303016.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-8876725 "Respiratory electron transport";"Protein methylation" XP_037298747.1 2 Reactome: R-HSA-5687128;KEGG: 04150+2.7.11.24 "MAPK6/MAPK4 signaling";"mTOR signaling pathway" XP_030022264.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030027153.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_037299104.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_037295984.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030035816.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037302835.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_037297331.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037300294.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037295334.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037302015.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_037300460.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030027354.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_030036689.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_030023997.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8854214 "RAB geranylgeranylation";"TBC/RABGAPs" XP_037295643.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_030034178.2 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037301510.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037295487.1 16 Reactome: R-HSA-975155;Reactome: R-HSA-1257604;Reactome: R-HSA-5602498;Reactome: R-HSA-5602680;Reactome: R-HSA-9020702;Reactome: R-HSA-975871;Reactome: R-HSA-975138;Reactome: R-HSA-975110;Reactome: R-HSA-5603041;Reactome: R-HSA-166058;Reactome: R-HSA-1236974;Reactome: R-HSA-5603037;Reactome: R-HSA-1810476;Reactome: R-HSA-209543;Reactome: R-HSA-3134963;Reactome: R-HSA-6811558 "MyD88 dependent cascade initiated on endosome";"PIP3 activates AKT signaling";"MyD88 deficiency (TLR2/4)";"MyD88 deficiency (TLR5)";"Interleukin-1 signaling";"MyD88 cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"IRAK4 deficiency (TLR2/4)";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"ER-Phagosome pathway";"IRAK4 deficiency (TLR5)";"RIP-mediated NFkB activation via ZBP1";"p75NTR recruits signalling complexes";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_030025217.1 5 Reactome: R-HSA-389661;MetaCyc: PWY-7382;MetaCyc: PWY-6987;KEGG: 00785+6.3.1.20;KEGG: 00785+2.3.1.181 "Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Lipoic acid metabolism" XP_030023671.1 8 Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1 "Glycolysis";"Streptomycin biosynthesis";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Galactose metabolism";"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis" XP_030040874.1 3 Reactome: R-HSA-6806664;KEGG: 00130+1.17.4.4;MetaCyc: PWY-7999 "Metabolism of vitamin K";"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle" XP_030032471.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037299056.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_037297928.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_030029332.2 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" XP_037292805.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_030031738.1 9 Reactome: R-HSA-6782135;Reactome: R-HSA-5696394;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-8951664 "Dual incision in TC-NER";"DNA Damage Recognition in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Neddylation" XP_030021025.2 16 Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-6791226 "Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037296929.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_037299979.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_037297111.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_030025219.1 5 Reactome: R-HSA-389661;MetaCyc: PWY-7382;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;KEGG: 00785+6.3.1.20 "Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Lipoic acid metabolism" XP_037297657.1 18 Reactome: R-HSA-1482925;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-8051;MetaCyc: PWY-6803;MetaCyc: PWY-7417;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;Reactome: R-HSA-1483166;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416 "Acyl chain remodelling of PG";"Plasmalogen degradation";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Acyl chain remodelling of PI";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Synthesis of PA";"Linoleic acid metabolism";"Acyl chain remodelling of PS";"Anandamide biosynthesis II";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)" XP_037293675.1 7 Reactome: R-HSA-5674400;Reactome: R-HSA-165181;Reactome: R-HSA-198323;Reactome: R-HSA-1632852;Reactome: R-HSA-8854214;Reactome: R-HSA-380972;Reactome: R-HSA-5628897 "Constitutive Signaling by AKT1 E17K in Cancer";"Inhibition of TSC complex formation by PKB";"AKT phosphorylates targets in the cytosol";"Macroautophagy";"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes" XP_030023397.2 9 Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167162 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape" XP_030034270.2 7 Reactome: R-HSA-71064;KEGG: 00380+2.3.1.61;Reactome: R-HSA-389661;Reactome: R-HSA-71403;MetaCyc: PWY-5084;KEGG: 00020+2.3.1.61;KEGG: 00310+2.3.1.61 "Lysine catabolism";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Citric acid cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Lysine degradation" XP_037298072.1 4 MetaCyc: PWY-7494;MetaCyc: PWY-3722;Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1 "Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism";"Glycine, serine and threonine metabolism" XP_030019868.2 6 MetaCyc: PWY-6368;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660516;Reactome: R-HSA-1855183;Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.66 "3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism" XP_030024423.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030023952.2 12 Reactome: R-HSA-156827;Reactome: R-HSA-166208;Reactome: R-HSA-72702;Reactome: R-HSA-429947;Reactome: R-HSA-72649;Reactome: R-HSA-72662;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-1169408;Reactome: R-HSA-72706 "L13a-mediated translational silencing of Ceruloplasmin expression";"mTORC1-mediated signalling";"Ribosomal scanning and start codon recognition";"Deadenylation of mRNA";"Translation initiation complex formation";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"ISG15 antiviral mechanism";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_030026356.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-9010553 "Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs" XP_030020400.2 1 Reactome: R-HSA-8949613 "Cristae formation" XP_030028628.1 24 Reactome: R-HSA-400042;Reactome: R-HSA-4086398;Reactome: R-HSA-381676;Reactome: R-HSA-8964616;Reactome: R-HSA-418597;Reactome: R-HSA-500657;Reactome: R-HSA-420092;Reactome: R-HSA-428930;Reactome: R-HSA-432040;Reactome: R-HSA-416476;Reactome: R-HSA-202040;Reactome: R-HSA-418555;Reactome: R-HSA-9009391;Reactome: R-HSA-8964315;Reactome: R-HSA-392451;Reactome: R-HSA-163359;Reactome: R-HSA-392851;Reactome: R-HSA-418592;Reactome: R-HSA-418217;Reactome: R-HSA-456926;Reactome: R-HSA-418594;Reactome: R-HSA-416482;Reactome: R-HSA-392170;Reactome: R-HSA-6814122 "Adrenaline,noradrenaline inhibits insulin secretion";"Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through CDC42";"G alpha (z) signalling events";"Presynaptic function of Kainate receptors";"Glucagon-type ligand receptors";"Thromboxane signalling through TP receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (q) signalling events";"G-protein activation";"G alpha (s) signalling events";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through BTK";"G beta:gamma signalling through PI3Kgamma";"Glucagon signaling in metabolic regulation";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PLC beta";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (i) signalling events";"G alpha (12/13) signalling events";"ADP signalling through P2Y purinoceptor 12";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_037297674.1 6 MetaCyc: PWY-6118;MetaCyc: PWY-6952;KEGG: 00564+1.1.5.3;MetaCyc: PWY-4261;Reactome: R-HSA-1483166;Reactome: R-HSA-163560 "Glycerol-3-phosphate shuttle";"Glycerophosphodiester degradation";"Glycerophospholipid metabolism";"Glycerol degradation I";"Synthesis of PA";"Triglyceride catabolism" XP_030036538.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_037300030.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_030030451.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_030027851.2 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" XP_037301834.1 4 MetaCyc: PWY-7887;Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+2.8.1.12 "Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_030022789.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037300539.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_037295105.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_037294969.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037293936.1 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" XP_037298054.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030032751.1 4 Reactome: R-HSA-1855183;KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841;KEGG: 00053+1.13.99.1 "Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Ascorbate and aldarate metabolism" XP_030021016.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72689 "Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits" XP_030029676.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037294588.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_030022797.1 3 Reactome: R-HSA-5173105;Reactome: R-HSA-5083627;Reactome: R-HSA-2022854 "O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6";"Keratan sulfate biosynthesis" XP_030029771.1 12 Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-205043;Reactome: R-HSA-1251985;Reactome: R-HSA-9013507;Reactome: R-HSA-9017802;Reactome: R-HSA-977225;Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-3928665;Reactome: R-HSA-2979096;Reactome: R-HSA-9013700 "Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NRIF signals cell death from the nucleus";"Nuclear signaling by ERBB4";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Amyloid fiber formation";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus" XP_030027075.2 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_037297230.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030026103.2 56 Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-5362768;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-174154;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-1234176;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553 "Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"ABC-family proteins mediated transport";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Vpu mediated degradation of CD4";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs" XP_037298557.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037301891.1 7 MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461 "Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Betanidin degradation" XP_037292632.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_030036957.2 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_030025265.1 5 MetaCyc: PWY-6344;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981;Reactome: R-HSA-8964539 "L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism" XP_030023448.2 21 MetaCyc: PWY-7210;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7197;MetaCyc: PWY-7176;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7205;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7187;KEGG: 00230+2.7.4.6+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7227;MetaCyc: PWY-7226;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7220;MetaCyc: PWY-7184;MetaCyc: PWY-7219;MetaCyc: PWY-6545;MetaCyc: PWY-7198;MetaCyc: PWY-7221 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotide phosphorylation";"UTP and CTP de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Thiamine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine ribonucleotides de novo biosynthesis" XP_037300780.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037297100.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_037294273.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037301018.1 7 MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-5469 "Matairesinol biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Sesamin biosynthesis" XP_037299834.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037294098.1 2 Reactome: R-HSA-6785470;Reactome: R-HSA-6784531 "tRNA processing in the mitochondrion";"tRNA processing in the nucleus" XP_037302894.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_030022534.1 3 Reactome: R-HSA-1474151;KEGG: 00790+1.1.1.153;Reactome: R-HSA-203615 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis";"eNOS activation" XP_030037635.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_030021062.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030041049.2 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_030034960.1 5 Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-3214815;Reactome: R-HSA-2894862 "NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_030031974.2 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_037297604.1 14 Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-110320 "Translesion synthesis by REV1";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Translesion synthesis by POLI";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH" XP_030024747.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_030022366.2 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037299370.1 14 MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7725 "Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_037293304.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_037293774.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_030030200.2 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_030033586.2 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" XP_030030326.2 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_037299313.1 5 Reactome: R-HSA-5674400;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-1257604 "Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling" XP_037298369.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_030031427.1 4 MetaCyc: PWY-7174;Reactome: R-HSA-1237112;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism" XP_030021067.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037297865.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037302184.1 3 MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757 "Folate polyglutamylation";"Folate biosynthesis";"Metabolism of folate and pterines" XP_030038851.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_030026668.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-2173788 "UCH proteinases";"Downregulation of TGF-beta receptor signaling" XP_037295719.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037297695.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_030021233.1 22 MetaCyc: PWY-6958;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7592;MetaCyc: PWY-7728;MetaCyc: PWY-8041;MetaCyc: PWY-7606;MetaCyc: PWY-5353;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7049;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7053;MetaCyc: PWY-6598;Reactome: R-HSA-75876;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7724;MetaCyc: PWY-7727;MetaCyc: PWY-7726;MetaCyc: PWY-7035 "Icosapentaenoate biosynthesis I (lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Ultra-long-chain fatty acid biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(9Z)-tricosene biosynthesis" XP_030020198.1 7 Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-8950505;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390450 "Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC" XP_030040487.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957 "Eukaryotic Translation Termination";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_030019721.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_030040202.1 1 Reactome: R-HSA-5626467 "RHO GTPases activate IQGAPs" XP_030020242.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030024645.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030020275.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_037295435.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_037294963.1 7 Reactome: R-HSA-5083628;Reactome: R-HSA-3000171;Reactome: R-HSA-5083629;Reactome: R-HSA-9010553;Reactome: R-HSA-5083633;Reactome: R-HSA-5173105;Reactome: R-HSA-3000178 "Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Regulation of expression of SLITs and ROBOs";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation";"ECM proteoglycans" XP_030027096.2 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_030027624.2 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" XP_030029341.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_037294699.1 4 KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614 "Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage" XP_030023477.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-983231 "Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production" XP_037298633.1 3 Reactome: R-HSA-174403;KEGG: 00480+4.3.2.9;MetaCyc: PWY-4041 "Glutathione synthesis and recycling";"Glutathione metabolism";"Gamma-glutamyl cycle" XP_037293631.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037299857.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_037295128.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-9033500 "Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins" XP_030028830.2 4 MetaCyc: PWY-6309;MetaCyc: PWY-5651;Reactome: R-HSA-71240;KEGG: 00380+3.7.1.3 "L-tryptophan degradation XI (mammalian, via kynurenine)";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Tryptophan catabolism";"Tryptophan metabolism" XP_030029637.1 3 KEGG: 00511+3.2.1.25;Reactome: R-HSA-6798695;Reactome: R-HSA-8853383 "Other glycan degradation";"Neutrophil degranulation";"Lysosomal oligosaccharide catabolism" XP_030024322.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_037298910.1 3 Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33 "Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis" XP_037296512.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_037301127.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037293843.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037302439.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037302627.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_030034827.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037296040.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_030041164.2 13 KEGG: 00760+3.6.1.9;MetaCyc: PWY-7206;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00230+3.6.1.9;KEGG: 00770+3.6.1.9;KEGG: 00230+3.6.1.66;MetaCyc: PWY-7184;MetaCyc: PWY-6545;Reactome: R-HSA-74259;KEGG: 00500+3.6.1.9 "Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine metabolism";"Tunicamycin biosynthesis";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pantothenate and CoA biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine catabolism";"Starch and sucrose metabolism" XP_030031561.2 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_037298415.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_030024752.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037293694.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037295982.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037294492.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_030029984.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037300298.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_037294504.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037299258.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_037303565.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030032290.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_037298609.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_030030822.2 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" XP_030035612.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_030024711.2 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_030028189.2 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037292633.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037299139.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_037296584.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_030022960.1 56 Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-8939236;Reactome: R-HSA-8939902;Reactome: R-HSA-69601;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-5607764;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-174084 "Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX2 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CLEC7A (Dectin-1) signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C" XP_030020755.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037303575.1 12 Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-73762;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-3214847;Reactome: R-HSA-5250924 "RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RNA Polymerase I Transcription Initiation";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"B-WICH complex positively regulates rRNA expression" XP_030040643.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_030028527.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030027662.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_030021720.1 11 Reactome: R-HSA-2151201;Reactome: R-HSA-611105;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-1268020;Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-3299685;Reactome: R-HSA-111457;Reactome: R-HSA-9627069;Reactome: R-HSA-5628897 "Transcriptional activation of mitochondrial biogenesis";"Respiratory electron transport";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Mitochondrial protein import";"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"Detoxification of Reactive Oxygen Species";"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity";"TP53 Regulates Metabolic Genes" XP_037302148.1 3 KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1 "Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis" XP_037300738.1 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_030019541.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030034343.2 1 Reactome: R-HSA-3295583 "TRP channels" XP_030019968.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037298745.1 2 Reactome: R-HSA-5687128;KEGG: 04150+2.7.11.24 "MAPK6/MAPK4 signaling";"mTOR signaling pathway" XP_030019833.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037303608.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_037294444.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" XP_030023612.2 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_030023652.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_037295070.1 5 Reactome: R-HSA-9013973;Reactome: R-HSA-936440;Reactome: R-HSA-936964;Reactome: R-HSA-918233;Reactome: R-HSA-933541 "TICAM1-dependent activation of IRF3/IRF7";"Negative regulators of DDX58/IFIH1 signaling";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF3-dependent IRF activation pathway";"TRAF6 mediated IRF7 activation" XP_037302862.1 4 Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216 "Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization" XP_030028187.2 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_030022839.2 5 MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922 "Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_037298760.1 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" XP_030037540.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_037293404.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037298981.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_030020316.2 2 KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281 "Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_030032328.1 12 MetaCyc: PWY-5857;MetaCyc: PWY-5855;Reactome: R-HSA-2142789;MetaCyc: PWY-5870;MetaCyc: PWY-5871;MetaCyc: PWY-7233;MetaCyc: PWY-7230;MetaCyc: PWY-5873;MetaCyc: PWY-5856;MetaCyc: PWY-5872;MetaCyc: PWY-6708;KEGG: 00130+1.14.99.60 "Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_037301972.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_037293736.1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway" XP_030030271.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030019944.2 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037300975.1 1 Reactome: R-HSA-8950505 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_037293370.1 4 Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-445095 "RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins" XP_030028995.1 8 MetaCyc: PWY-7210;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-6545;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7198 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" XP_037298051.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037292980.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_037294083.1 8 Reactome: R-HSA-5083633;Reactome: R-HSA-5173105;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083629;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921 "Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)" XP_030029317.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_030029894.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030028070.1 7 MetaCyc: PWY-46;MetaCyc: PWY-4984;Reactome: R-HSA-70635;KEGG: 00220+3.5.3.1;MetaCyc: PWY-31;MetaCyc: PWY-6922;KEGG: 00330+3.5.3.1 "Putrescine biosynthesis III";"Urea cycle";"Urea cycle";"Arginine biosynthesis";"Canavanine degradation";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism" XP_037292399.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037293918.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_030026780.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_030029398.2 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection" XP_030038881.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_030032570.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_030025537.1 4 Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590 "Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"NIK-->noncanonical NF-kB signaling" XP_037297589.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_037303090.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_030031766.1 7 MetaCyc: PWY-5469;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5466 "Sesamin biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Matairesinol biosynthesis" XP_037294782.1 4 Reactome: R-HSA-912631;Reactome: R-HSA-8875555;Reactome: R-HSA-8875656;Reactome: R-HSA-186763 "Regulation of signaling by CBL";"MET activates RAP1 and RAC1";"MET receptor recycling";"Downstream signal transduction" XP_037299413.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_030025176.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_037292186.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_037294366.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037292864.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_037296500.1 4 Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5676590 "Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling" XP_030020693.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_037300758.1 6 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-5632684;Reactome: R-HSA-75955;Reactome: R-HSA-201722;Reactome: R-HSA-8866654 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Hedgehog 'on' state";"RNA Polymerase II Transcription Elongation";"Formation of the beta-catenin:TCF transactivating complex";"E3 ubiquitin ligases ubiquitinate target proteins" XP_030023028.1 3 MetaCyc: PWY-6100;Reactome: R-HSA-71262;KEGG: 00310+1.14.11.8 "L-carnitine biosynthesis";"Carnitine synthesis";"Lysine degradation" XP_037303274.1 5 Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-109704;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001 "Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K Cascade";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade" XP_030020179.2 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_030025377.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_030037490.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_030022393.2 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_037297232.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037295510.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_037299292.1 11 Reactome: R-HSA-8866654;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1834949;Reactome: R-HSA-3270619;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693571;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "E3 ubiquitin ligases ubiquitinate target proteins";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Nonhomologous End-Joining (NHEJ)";"Relaxin signaling pathway";"mTOR signaling pathway" XP_030034095.1 27 Reactome: R-HSA-159231;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749 "Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs" XP_030019986.1 5 Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-69205 "Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"G1/S-Specific Transcription" XP_037303286.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_030040868.2 13 Reactome: R-HSA-2132295;Reactome: R-HSA-8866427;Reactome: R-HSA-437239;Reactome: R-HSA-3928665;Reactome: R-HSA-177504;Reactome: R-HSA-8856825;Reactome: R-HSA-182218;Reactome: R-HSA-416993;Reactome: R-HSA-8856828;Reactome: R-HSA-167590;Reactome: R-HSA-5140745;Reactome: R-HSA-8964038;Reactome: R-HSA-5099900 "MHC class II antigen presentation";"VLDLR internalisation and degradation";"Recycling pathway of L1";"EPH-ephrin mediated repulsion of cells";"Retrograde neurotrophin signalling";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD8 Down-regulation";"Trafficking of GluR2-containing AMPA receptors";"Clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"LDL clearance";"WNT5A-dependent internalization of FZD4" XP_030029004.1 3 Reactome: R-HSA-6784531;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766 "tRNA processing in the nucleus";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion" XP_037300072.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_030019734.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" XP_037293552.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_030035329.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_030027253.2 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_037298542.1 2 Reactome: R-HSA-5693571;Reactome: R-HSA-164843 "Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation" XP_030040153.2 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037296733.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_037298799.1 20 MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-5136;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-735;MetaCyc: PWY-7288;MetaCyc: PWY-6920;MetaCyc: PWY-7338;MetaCyc: PWY-7854;MetaCyc: PWY-7858;MetaCyc: PWY-7337;MetaCyc: PWY-7007;MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6837;KEGG: 00592+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7726 "Propanoyl-coa degradation II";"beta-Alanine metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoate metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation VII (yeast peroxisome)";"6-gingerol analog biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(5Z)-dodecenoate biosynthesis II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Methyl ketone biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"alpha-Linolenic acid metabolism";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)" XP_037293703.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037296718.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_030040353.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_030036702.2 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_030028185.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_037298564.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_037300679.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_030019834.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_030026070.2 1 Reactome: R-HSA-1614603 "Cysteine formation from homocysteine" XP_037303041.1 24 Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-9648025;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-9646399 "Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Cilium Assembly";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"EML4 and NUDC in mitotic spindle formation";"Kinesins";"Recycling pathway of L1";"Mitotic Prometaphase";"Aggrephagy" XP_030035885.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_037302939.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_030040616.1 5 KEGG: 00240+2.4.2.3;MetaCyc: PWY-5532;Reactome: R-HSA-73621;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614 "Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine catabolism";"Drug metabolism - other enzymes";"Pyrimidine salvage" XP_030026940.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_030036467.2 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037293883.1 9 MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52 "Chitin degradation II (Vibrio)";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series" XP_037292454.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030033104.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_037292898.1 7 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway" XP_030027619.2 3 Reactome: R-HSA-9609523;Reactome: R-HSA-6798695;Reactome: R-HSA-1660661 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Neutrophil degranulation";"Sphingolipid de novo biosynthesis" XP_037297783.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_037293154.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_037298899.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_030029117.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037292646.1 6 Reactome: R-HSA-191273;KEGG: 00900+2.7.1.36;MetaCyc: PWY-922;Reactome: R-HSA-2426168;MetaCyc: PWY-7391;MetaCyc: PWY-6174 "Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)" XP_030024281.2 5 MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-6902 "Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)" XP_037302442.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037292618.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037293235.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037295535.1 11 Reactome: R-HSA-8964539;MetaCyc: PWY-6964;Reactome: R-HSA-210455;MetaCyc: PWY-6549;KEGG: 00220+6.3.1.2;KEGG: 00250+6.3.1.2;KEGG: 00910+6.3.1.2;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6963;MetaCyc: PWY-5675;MetaCyc: PWY-381 "Glutamate and glutamine metabolism";"Ammonia assimilation cycle II";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"L-glutamine biosynthesis III";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle I";"Nitrate reduction V (assimilatory)";"Nitrate reduction II (assimilatory)" XP_037294720.1 13 Reactome: R-HSA-381676;Reactome: R-HSA-4086398;Reactome: R-HSA-114508;Reactome: R-HSA-139853;Reactome: R-HSA-2029485;Reactome: R-HSA-112043;Reactome: R-HSA-5607763;Reactome: R-HSA-2871809;Reactome: R-HSA-5578775;Reactome: R-HSA-5218921;Reactome: R-HSA-1489509;Reactome: R-HSA-983695;Reactome: R-HSA-422356 "Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway";"Effects of PIP2 hydrolysis";"Elevation of cytosolic Ca2+ levels";"Role of phospholipids in phagocytosis";"PLC beta mediated events";"CLEC7A (Dectin-1) induces NFAT activation";"FCERI mediated Ca+2 mobilization";"Ion homeostasis";"VEGFR2 mediated cell proliferation";"DAG and IP3 signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Regulation of insulin secretion" XP_037300755.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_030028538.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037296568.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_030027626.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_030024081.2 7 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway" XP_030027674.1 20 Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-5656121;Reactome: R-HSA-176187;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-110320 "Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"Translesion synthesis by POLI";"Activation of ATR in response to replication stress";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH" XP_030029873.1 2 KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10 "Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism" XP_037299289.1 7 Reactome: R-HSA-110362;Reactome: R-HSA-5696394;Reactome: R-HSA-2173795;Reactome: R-HSA-5685939;Reactome: R-HSA-5696400;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395 "POLB-Dependent Long Patch Base Excision Repair";"DNA Damage Recognition in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"HDR through MMEJ (alt-NHEJ)";"Dual Incision in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER" XP_030025606.1 29 Reactome: R-HSA-5696400;Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-167160;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-5696395;Reactome: R-HSA-73863;Reactome: R-HSA-113418;Reactome: R-HSA-6782135;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-73772;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-77075 "Dual Incision in GG-NER";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Termination";"Formation of the Early Elongation Complex";"Dual incision in TC-NER";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE" XP_037297352.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_037302656.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_030040092.1 24 Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-380320 "RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"HCMV Early Events";"MHC class II antigen presentation";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Kinesins";"Recycling pathway of L1";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes" XP_030029119.1 3 Reactome: R-HSA-111471;Reactome: R-HSA-140837;Reactome: R-HSA-9645722 "Apoptotic factor-mediated response";"Intrinsic Pathway of Fibrin Clot Formation";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function" XP_037301030.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_030025998.1 20 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-8943724;Reactome: R-HSA-6804757;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;KEGG: 05170+2.7.11.1;Reactome: R-HSA-166208;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;Reactome: R-HSA-380972;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"HSF1-dependent transactivation";"mTOR signalling";"Amino acids regulate mTORC1";"Relaxin signaling pathway";"VEGFR2 mediated vascular permeability";"Regulation of PTEN gene transcription";"Regulation of TP53 Degradation";"PI3K-Akt signaling pathway";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Human immunodeficiency virus 1 infection";"mTORC1-mediated signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human cytomegalovirus infection" XP_030029298.1 5 KEGG: 00240+2.4.2.3;MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73621;Reactome: R-HSA-73614 "Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes";"Pyrimidine catabolism";"Pyrimidine salvage" XP_037294372.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037300179.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037292312.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_030023152.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030027583.1 14 Reactome: R-HSA-426496;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-203927;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692 "Post-transcriptional silencing by small RNAs";"Ca2+ pathway";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"MicroRNA (miRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity" XP_030029913.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_037301382.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-6784531;Reactome: R-HSA-72163;Reactome: R-HSA-77595 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"tRNA processing in the nucleus";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs" XP_037292314.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_030025314.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_030031394.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_037298498.1 12 Reactome: R-HSA-73772;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-73863;Reactome: R-HSA-73780;Reactome: R-HSA-5250924;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-76061 "RNA Polymerase I Promoter Escape";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Chain Elongation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_037298013.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_030035948.2 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_037295488.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_030036057.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_037297090.1 5 MetaCyc: PWY-3341;MetaCyc: PWY-6344;MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539 "L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism" XP_030032523.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030021581.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72689 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits" XP_030022343.2 4 KEGG: 00010+3.1.3.9;KEGG: 00500+3.1.3.9;Reactome: R-HSA-70263;KEGG: 00052+3.1.3.9 "Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Gluconeogenesis";"Galactose metabolism" XP_030027617.2 6 Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;MetaCyc: PWY-6829;Reactome: R-HSA-6787450;MetaCyc: PWY-7285;MetaCyc: PWY-7286 "rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"Trna methylation (yeast)";"tRNA modification in the mitochondrion";"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis" XP_037292415.1 12 Reactome: R-HSA-1442490;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-1251985;Reactome: R-HSA-177929;Reactome: R-HSA-75893;Reactome: R-HSA-982772;Reactome: R-HSA-2644606;Reactome: R-HSA-5362798;Reactome: R-HSA-193692;Reactome: R-HSA-2660826 "Collagen degradation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Nuclear signaling by ERBB4";"Signaling by EGFR";"TNF signaling";"Growth hormone receptor signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Release of Hh-Np from the secreting cell";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant" XP_037301622.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_030019945.2 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_030027080.1 7 Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-1989781;Reactome: R-HSA-2173796;Reactome: R-HSA-2122947;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"PPARA activates gene expression";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_030031296.2 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_037295407.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_037301245.1 14 MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-5972 "Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)" XP_030031359.1 5 Reactome: R-HSA-5689901;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565 "Metalloprotease DUBs";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_030024561.2 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_030025417.2 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_030027146.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_037292421.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-936837 "Neutrophil degranulation";"Ion transport by P-type ATPases" XP_030035034.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037297971.1 9 KEGG: 00960+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00401+2.6.1.5;Reactome: R-HSA-8963684 "Tropane, piperidine and pyridine alkaloid biosynthesis";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism";"Cysteine and methionine metabolism";"Novobiocin biosynthesis";"Tyrosine catabolism" XP_037295992.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030024710.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037298269.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_030040330.1 11 Reactome: R-HSA-6785631;Reactome: R-HSA-1227986;Reactome: R-HSA-1257604;Reactome: R-HSA-1250196;Reactome: R-HSA-9664565;Reactome: R-HSA-8847993;Reactome: R-HSA-1963642;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-8863795;Reactome: R-HSA-6811558 "ERBB2 Regulates Cell Motility";"Signaling by ERBB2";"PIP3 activates AKT signaling";"SHC1 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"ERBB2 Activates PTK6 Signaling";"PI3K events in ERBB2 signaling";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"Downregulation of ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_037300220.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030020174.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_030029086.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_030036175.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_030039072.1 52 Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-73772;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-72203;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-5601884;Reactome: R-HSA-73863;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-167160;Reactome: R-HSA-167162;Reactome: R-HSA-72163;Reactome: R-HSA-8851708;Reactome: R-HSA-6782210;Reactome: R-HSA-5250924;Reactome: R-HSA-9018519;Reactome: R-HSA-76061;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-72165;Reactome: R-HSA-167287;Reactome: R-HSA-167161;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-674695;Reactome: R-HSA-73780;Reactome: R-HSA-113418;Reactome: R-HSA-73980;Reactome: R-HSA-6782135;Reactome: R-HSA-73762;Reactome: R-HSA-167242;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-168325;Reactome: R-HSA-167152;Reactome: R-HSA-6803529;Reactome: R-HSA-5617472;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-203927;Reactome: R-HSA-167238;Reactome: R-HSA-1834949;Reactome: R-HSA-72086;Reactome: R-HSA-73776;Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-167158 "Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase I Transcription Termination";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II HIV Promoter Escape";"mRNA Splicing - Major Pathway";"Signaling by FGFR2 IIIa TM";"Gap-filling DNA repair synthesis and ligation in TC-NER";"B-WICH complex positively regulates rRNA expression";"Estrogen-dependent gene expression";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Minor Pathway";"HIV elongation arrest and recovery";"HIV Transcription Initiation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase III Chain Elongation";"Formation of the Early Elongation Complex";"RNA Polymerase III Transcription Termination";"Dual incision in TC-NER";"RNA Polymerase I Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Viral Messenger RNA Synthesis";"Formation of HIV elongation complex in the absence of HIV Tat";"FGFR2 alternative splicing";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"MicroRNA (miRNA) biogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"Cytosolic sensors of pathogen-associated DNA";"mRNA Capping";"RNA Polymerase II Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex" XP_037295628.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037295574.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_037302675.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_030027987.1 2 MetaCyc: PWY-5697;KEGG: 00230+3.5.3.4 "Allantoin degradation to ureidoglycolate I (urea producing)";"Purine metabolism" XP_037299776.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_030037621.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037299583.1 2 KEGG: 00280+1.3.8.4;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism" XP_037298709.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_030033763.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_030024658.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823 "mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex" XP_030021780.1 8 KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171 "Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Galactose metabolism";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Glycolysis" XP_037300355.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_030028508.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_030041067.2 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_030028604.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_030022662.2 3 Reactome: R-HSA-191859;Reactome: R-HSA-3214858;Reactome: R-HSA-6804760 "snRNP Assembly";"RMTs methylate histone arginines";"Regulation of TP53 Activity through Methylation" XP_030032171.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_037302268.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_030022450.1 1 Reactome: R-HSA-200425 "Carnitine metabolism" XP_030026218.1 4 KEGG: 00270+1.13.11.20;KEGG: 00430+1.13.11.20;MetaCyc: PWY-5331;Reactome: R-HSA-1614558 "Cysteine and methionine metabolism";"Taurine and hypotaurine metabolism";"Taurine biosynthesis I";"Degradation of cysteine and homocysteine" XP_030036712.2 12 KEGG: 00051+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-1861;KEGG: 00710+4.1.2.13;KEGG: 00010+4.1.2.13;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1042;Reactome: R-HSA-70171;Reactome: R-HSA-70263;KEGG: 00680+4.1.2.13 "Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Glycolysis";"Gluconeogenesis";"Methane metabolism" XP_030034465.2 4 Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395 "Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER" XP_037292264.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_037292553.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex" XP_030031127.2 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_030026545.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_030022414.2 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_030032900.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_030021028.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037300111.1 8 MetaCyc: PWY-7400;MetaCyc: PWY-5;MetaCyc: PWY-4983;KEGG: 00250+6.3.4.5;MetaCyc: PWY-5154;Reactome: R-HSA-70635;KEGG: 00220+6.3.4.5;MetaCyc: PWY-4984 "L-arginine biosynthesis IV (archaebacteria)";"Canavanine biosynthesis";"Nitric oxide biosynthesis II (mammals)";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Urea cycle";"Arginine biosynthesis";"Urea cycle" XP_037298714.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606 "NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_037293627.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037295273.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_030040080.2 4 KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-4720454;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.261 "N-Glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis" XP_030029787.2 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_037303172.1 2 Reactome: R-HSA-3214815;Reactome: R-HSA-427413 "HDACs deacetylate histones";"NoRC negatively regulates rRNA expression" XP_030029065.2 2 KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281 "Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_030041171.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" XP_030040895.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_030024078.2 7 KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway" XP_030034776.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030030164.1 3 Reactome: R-HSA-6783984;KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine degradation";"Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_030035177.2 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_030022123.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-390471;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins" XP_037292258.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection" XP_030033224.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037302388.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037294819.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037300572.1 12 MetaCyc: PWY-5188;Reactome: R-HSA-6798695;Reactome: R-HSA-381042;MetaCyc: PWY-5189;Reactome: R-HSA-114608;Reactome: R-HSA-983170;Reactome: R-HSA-381033;KEGG: 00860+4.2.1.24;Reactome: R-HSA-189451;Reactome: R-HSA-381070;Reactome: R-HSA-381183;Reactome: R-HSA-3371453 "Tetrapyrrole biosynthesis I (from glutamate)";"Neutrophil degranulation";"PERK regulates gene expression";"Tetrapyrrole biosynthesis II (from glycine)";"Platelet degranulation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperones";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"IRE1alpha activates chaperones";"ATF6 (ATF6-alpha) activates chaperone genes";"Regulation of HSF1-mediated heat shock response" XP_030041393.2 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037293480.1 4 Reactome: R-HSA-8849175;MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-5358493 "Threonine catabolism";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2" XP_037294721.1 56 Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-4641258 "Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Degradation of DVL" XP_037293367.1 4 Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport" XP_037299607.1 2 Reactome: R-HSA-2022928;MetaCyc: PWY-6558 "HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)" XP_037296156.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037299612.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_037300329.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-983168 "Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_030021976.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" XP_030033419.2 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_030031122.2 7 MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469 "Justicidin B biosynthesis";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis" XP_030035260.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_037292757.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_030031903.1 2 Reactome: R-HSA-190373;Reactome: R-HSA-5654726 "FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling" XP_037302043.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_030024448.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_030020808.2 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_030041289.1 6 Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-434316 "G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion" XP_037295860.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_030028363.2 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_030030750.2 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_037293498.1 7 KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis" XP_030040386.1 5 Reactome: R-HSA-5632684;Reactome: R-HSA-373080;Reactome: R-HSA-5610787;Reactome: R-HSA-5635838;Reactome: R-HSA-5620922 "Hedgehog 'on' state";"Class B/2 (Secretin family receptors)";"Hedgehog 'off' state";"Activation of SMO";"BBSome-mediated cargo-targeting to cilium" XP_037300452.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-174490 "Late endosomal microautophagy";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins" XP_037303011.1 6 Reactome: R-HSA-500753;MetaCyc: PWY-5686;KEGG: 00240+2.4.2.10;KEGG: 00983+2.4.2.10;MetaCyc: PWY-7790;MetaCyc: PWY-7791 "Pyrimidine biosynthesis";"UMP biosynthesis I";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"UMP biosynthesis II";"UMP biosynthesis III" XP_037302678.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_030034164.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_030034781.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037292792.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_037299381.1 11 KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052;Reactome: R-HSA-2029485;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8053;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;KEGG: 00565+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8055;MetaCyc: PWY-8051 "Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Role of phospholipids in phagocytosis";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Ether lipid metabolism";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I" XP_037300059.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037295068.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_030033669.1 3 MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217 "Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage" XP_030039527.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167162 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape" XP_030034962.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037294086.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_037296127.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_030038230.2 11 Reactome: R-HSA-193692;Reactome: R-HSA-2979096;Reactome: R-HSA-3928665;Reactome: R-HSA-2644606;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948 "Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_037295844.1 5 KEGG: 00630+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00720+4.2.1.3 "Glyoxylate and dicarboxylate metabolism";"Iron uptake and transport";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Carbon fixation pathways in prokaryotes" XP_037300412.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037299492.1 14 MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I" XP_030025267.2 4 KEGG: 00100+1.3.1.72;Reactome: R-HSA-6807047;Reactome: R-HSA-6807062;MetaCyc: PWY-8026 "Steroid biosynthesis";"Cholesterol biosynthesis via desmosterol";"Cholesterol biosynthesis via lathosterol";"Sterol biosynthesis (methylotrophs)" XP_037299441.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_030027199.2 17 Reactome: R-HSA-5696400;Reactome: R-HSA-174437;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-5358606;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-5358565;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-6782210;Reactome: R-HSA-174417;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-174414;Reactome: R-HSA-5651801 "Dual Incision in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand (Lagging Strand) Synthesis";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"Processive synthesis on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair" XP_037294671.1 5 Reactome: R-HSA-5689880;MetaCyc: PWY-7511;Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751 "Ub-specific processing proteases";"Protein ubiquitination";"TCF dependent signaling in response to WNT";"Degradation of AXIN";"Regulation of PTEN stability and activity" XP_037295214.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_030024942.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037300025.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_030034537.1 6 KEGG: 04070+3.1.3.36;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.36;Reactome: R-HSA-194840;Reactome: R-HSA-1855204;Reactome: R-HSA-1855183 "Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Rho GTPase cycle";"Synthesis of IP3 and IP4 in the cytosol";"Synthesis of IP2, IP, and Ins in the cytosol" XP_030034575.2 13 Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553 "SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs" XP_030027768.2 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation" XP_037294973.1 5 Reactome: R-HSA-3108214;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-5221030;Reactome: R-HSA-110357 "SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1" XP_030027504.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_037292755.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_030032296.1 4 Reactome: R-HSA-1268020;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial protein import";"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037303636.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_037299136.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_030024202.2 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_030030898.2 10 Reactome: R-HSA-70171;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00052+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-7385;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1861 "Glycolysis";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Galactose metabolism";"Methane metabolism";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" XP_030032164.1 2 Reactome: R-HSA-2024096;Reactome: R-HSA-2206307 "HS-GAG degradation";"MPS IIIA - Sanfilippo syndrome A" XP_037293236.1 3 Reactome: R-HSA-74217;MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20 "Purine salvage";"Adenine and adenosine salvage VI";"Purine metabolism" XP_037300470.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037294561.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_030033186.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_030026147.1 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_030036731.1 26 Reactome: R-HSA-1362277;Reactome: R-HSA-174417;Reactome: R-HSA-8866654;Reactome: R-HSA-6804114;Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-69205;Reactome: R-HSA-5655862;Reactome: R-HSA-174414;Reactome: R-HSA-4615885;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-174437;Reactome: R-HSA-69183;Reactome: R-HSA-5358606;Reactome: R-HSA-69166;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-5358565;Reactome: R-HSA-110314;Reactome: R-HSA-69091 "Transcription of E2F targets under negative control by DREAM complex";"Telomere C-strand (Lagging Strand) Synthesis";"E3 ubiquitin ligases ubiquitinate target proteins";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"G1/S-Specific Transcription";"Translesion synthesis by POLK";"Processive synthesis on the C-strand of the telomere";"SUMOylation of DNA replication proteins";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Removal of the Flap Intermediate from the C-strand";"Processive synthesis on the lagging strand";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching" XP_030032154.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037295125.1 2 Reactome: R-HSA-9033500;Reactome: R-HSA-9033241 "TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import" XP_037292668.1 4 Reactome: R-HSA-70688;MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922 "Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis" XP_030020365.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_030026518.1 56 Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-69601;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-8939902;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-382556;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-983168;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX2 expression and activity";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"ABC-family proteins mediated transport";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins" XP_037295317.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_030029224.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037300864.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_037294106.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_030038634.1 5 Reactome: R-HSA-168164;Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-937041 "Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1" XP_037293691.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_030024273.1 7 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection" XP_030027546.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_030030968.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030026819.1 5 Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_030032648.2 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_030032645.2 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037292470.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_030037380.2 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_030031742.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_037295833.1 10 Reactome: R-HSA-9022702;Reactome: R-HSA-9615017;Reactome: R-HSA-9022699;Reactome: R-HSA-9022538;Reactome: R-HSA-3899300;Reactome: R-HSA-427413;Reactome: R-HSA-983231;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-400206 "MECP2 regulates transcription of neuronal ligands";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"MECP2 regulates neuronal receptors and channels";"Loss of MECP2 binding ability to 5mC-DNA";"SUMOylation of transcription cofactors";"NoRC negatively regulates rRNA expression";"Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Regulation of lipid metabolism by PPARalpha" XP_030023830.2 5 Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-427413 "RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression" XP_037301102.1 10 Reactome: R-HSA-2197563;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-2122947;Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-350054 "NOTCH2 intracellular domain regulates transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway" XP_037296731.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_030029498.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_037296146.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030022206.2 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_030026620.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_030039540.1 9 Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-6804756 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation" XP_030025149.1 6 Reactome: R-HSA-1474151;MetaCyc: PWY-5664;MetaCyc: PWY-7442;KEGG: 00790+4.2.3.12;MetaCyc: PWY-6983;MetaCyc: PWY-5663 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis II";"Drosopterin and aurodrosopterin biosynthesis";"Folate biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I" XP_030024937.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_037303288.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037294925.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_030035651.1 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" XP_030035519.2 3 Reactome: R-HSA-6807505;Reactome: R-HSA-749476;Reactome: R-HSA-76071 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_030036185.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_030028875.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_030019653.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030032437.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_030028767.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_030025247.2 2 Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_030019919.2 1 Reactome: R-HSA-8876725 "Protein methylation" XP_030028386.1 1 Reactome: R-HSA-1474151 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_030025892.2 31 MetaCyc: PWY-5971;MetaCyc: PWY-5994;MetaCyc: PWY-7388;Reactome: R-HSA-199220;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7663;MetaCyc: PWY-5366;MetaCyc: PWY-5147;MetaCyc: PWYG-321;Reactome: R-HSA-2426168;MetaCyc: PWY-5142;MetaCyc: PWY-5989;Reactome: R-HSA-75105;MetaCyc: PWY-5973;MetaCyc: PWY-7858;MetaCyc: PWY-7746;MetaCyc: PWY-6113;MetaCyc: PWY-5966-1;MetaCyc: PWY-8047;MetaCyc: PWY-8012;MetaCyc: PWY-6799;MetaCyc: PWY-7664;MetaCyc: PWY-6519;MetaCyc: PWY-4381;Reactome: R-HSA-163765;MetaCyc: PWY-5367;MetaCyc: PWY-6282;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8049;MetaCyc: PWY-7723;Reactome: R-HSA-9029558 "Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Vitamin B5 (pantothenate) metabolism";"Fatty acid biosynthesis";"Gondoate biosynthesis (anaerobic)";"Palmitoleate biosynthesis II (plants and bacteria)";"Oleate biosynthesis I (plants)";"";"Activation of gene expression by SREBF (SREBP)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Stearate biosynthesis II (bacteria and plants)";"Fatty acyl-CoA biosynthesis";"Cis-vaccenate biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Mycobacterial sulfolipid biosynthesis";"Superpathway of mycolate biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Bryostatin biosynthesis";"Mupirocin biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Oleate biosynthesis IV (anaerobic)";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (bacteria and plants)";"ChREBP activates metabolic gene expression";"Petroselinate biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Biotin metabolism";"Pederin biosynthesis";"Bacterial bioluminescence";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis" XP_030040249.2 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_030027989.2 4 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_030035692.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_030025769.1 7 Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-1221632;Reactome: R-HSA-2559586;Reactome: R-HSA-171306 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Meiotic synapsis";"DNA Damage/Telomere Stress Induced Senescence";"Packaging Of Telomere Ends" XP_037300893.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_037293693.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_030028306.2 6 KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165;KEGG: 00030+3.1.1.17;MetaCyc: PWY-2221;KEGG: 00930+3.1.1.17;MetaCyc: PWY-5530 "Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)";"Pentose phosphate pathway";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Caprolactam degradation";"Sorbitol biosynthesis II" XP_030027411.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" XP_037299067.1 12 KEGG: 00261+2.7.7.4;Reactome: R-HSA-2408550;MetaCyc: PWY-5278;MetaCyc: PWY-6932;Reactome: R-HSA-174362;KEGG: 00230+2.7.1.25;KEGG: 00230+2.7.7.4;KEGG: 00450+2.7.7.4;MetaCyc: PWY-6683;KEGG: 00920+2.7.7.4;MetaCyc: PWY-5340;KEGG: 00920+2.7.1.25 "Monobactam biosynthesis";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfite oxidation III";"Selenate reduction";"Transport and synthesis of PAPS";"Purine metabolism";"Purine metabolism";"Selenocompound metabolism";"Assimilatory sulfate reduction III";"Sulfur metabolism";"Sulfate activation for sulfonation";"Sulfur metabolism" XP_030029170.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037302957.1 15 Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167238 "Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation" XP_030034285.1 3 Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-72165 "snRNP Assembly";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_030026248.2 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037300764.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_030024703.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037303413.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030032452.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807 "Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism" XP_037300141.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037300980.1 5 MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-6902 "Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)" XP_037303045.1 24 Reactome: R-HSA-1445148;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Kinesins";"Recycling pathway of L1";"Mitotic Prometaphase";"Aggrephagy";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors" XP_030033089.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_037297746.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_037300093.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_030027152.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_030026470.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_030026846.2 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_030035833.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823 "Eukaryotic Translation Termination";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation" XP_037293646.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-5689880 "G alpha (i) signalling events";"Degradation of AXIN";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases" XP_037300131.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037293441.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-375276 "G alpha (s) signalling events";"Peptide ligand-binding receptors" XP_037293651.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037296065.1 10 MetaCyc: PWY-6453;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-5667 "Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I" XP_030034967.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037298943.1 3 KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" XP_030035120.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_037297938.1 7 Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;MetaCyc: PWY-7511;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096 "Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus" XP_030024213.1 2 Reactome: R-HSA-168138;Reactome: R-HSA-983231 "Toll Like Receptor 9 (TLR9) Cascade";"Factors involved in megakaryocyte development and platelet production" XP_037292355.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_030027760.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_030031448.1 4 Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554 "Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_030035385.1 6 Reactome: R-HSA-9615017;Reactome: R-HSA-6798695;Reactome: R-HSA-3299685;Reactome: R-HSA-9033241;KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6 "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Neutrophil degranulation";"Detoxification of Reactive Oxygen Species";"Peroxisomal protein import";"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism" XP_037298798.1 20 MetaCyc: PWY-7574;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6;MetaCyc: PWY-5136;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7291;MetaCyc: PWY-7288;MetaCyc: PWY-7858;MetaCyc: PWY-7854;MetaCyc: PWY-7338;MetaCyc: PWY-6920;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7340;MetaCyc: PWY-7337;MetaCyc: PWY-6837;MetaCyc: PWY-7726;Reactome: R-HSA-9033241;KEGG: 00592+1.3.3.6 "Propanoyl-coa degradation II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"alpha-Linolenic acid metabolism" XP_030035383.1 2 Reactome: R-HSA-1236974;Reactome: R-HSA-1799339 "ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane" XP_030035966.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_030024900.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" XP_037298083.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_030028853.1 17 MetaCyc: PWY-5743;Reactome: R-HSA-200425;KEGG: 00620+6.4.1.2;Reactome: R-HSA-2426168;MetaCyc: PWY-5789;KEGG: 00720+6.4.1.2;MetaCyc: PWY-6722;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5966-1;KEGG: 00061+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-6679;MetaCyc: PWY-4381;Reactome: R-HSA-163765;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5744;Reactome: R-HSA-196780 "3-hydroxypropanoate cycle";"Carnitine metabolism";"Pyruvate metabolism";"Activation of gene expression by SREBF (SREBP)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Carbon fixation pathways in prokaryotes";"Candicidin biosynthesis";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"ChREBP activates metabolic gene expression";"Propanoate metabolism";"Glyoxylate assimilation";"Biotin transport and metabolism" XP_037298903.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_037300102.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_037294708.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_030038767.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_030031074.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_030021911.1 3 Reactome: R-HSA-427389;Reactome: R-HSA-73772;Reactome: R-HSA-8953750 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Escape";"Transcriptional Regulation by E2F6" XP_030025335.1 14 Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-203927;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-426496;Reactome: R-HSA-4086398 "Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"Post-transcriptional silencing by small RNAs";"Ca2+ pathway" XP_037301759.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037292688.1 6 Reactome: R-HSA-6804759;Reactome: R-HSA-139915;Reactome: R-HSA-6803205;Reactome: R-HSA-6803204;Reactome: R-HSA-6803211;Reactome: R-HSA-6803207 "Regulation of TP53 Activity through Association with Co-factors";"Activation of PUMA and translocation to mitochondria";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Caspase Activators and Caspases" XP_037297426.1 7 Reactome: R-HSA-2029485;Reactome: R-HSA-1483166;Reactome: R-HSA-1483148;MetaCyc: PWY-7039;KEGG: 00564+3.1.4.4;KEGG: 00565+3.1.4.4;MetaCyc: PWY-3561 "Role of phospholipids in phagocytosis";"Synthesis of PA";"Synthesis of PG";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Choline biosynthesis III" XP_030032709.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030032291.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300 "SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors" XP_030031608.2 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_037293799.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_037301590.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037297939.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037303129.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_030021378.1 2 KEGG: 00514+2.4.1.221;Reactome: R-HSA-1912399 "Other types of O-glycan biosynthesis";"Pre-NOTCH Processing in the Endoplasmic Reticulum" XP_037296185.1 5 MetaCyc: PWY-7761;MetaCyc: PWY-5381;Reactome: R-HSA-196807;MetaCyc: PWY-5653;KEGG: 00760+2.7.7.18 "NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism" XP_037292267.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_030021779.1 8 Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1 "Glycolysis";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Starch and sucrose metabolism" XP_037297380.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_030031725.1 9 Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-6782135;Reactome: R-HSA-8951664;Reactome: R-HSA-6782210;Reactome: R-HSA-110314 "Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Dual incision in TC-NER";"Neddylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex" XP_030026799.2 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_030024082.2 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_037299411.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_030032410.2 3 Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_037294503.1 3 Reactome: R-HSA-6806664;KEGG: 00130+1.17.4.4;MetaCyc: PWY-7999 "Metabolism of vitamin K";"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle" XP_030020638.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_030021061.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037292235.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_037297641.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_030023716.1 10 KEGG: 00670+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;MetaCyc: PWY-1722;MetaCyc: PWY-5497;MetaCyc: PWY-5030;MetaCyc: PWY-2201;MetaCyc: PWY-7909;MetaCyc: PWY-3841;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613 "One carbon pool by folate";"Metabolism of folate and pterines";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"L-histidine degradation III";"Folate transformations I";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate" XP_030028761.2 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_037302019.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_030023300.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553 "Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs" XP_030029945.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030034756.2 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037292674.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030021246.1 56 Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-8939902;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-1234176;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-174154;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-5362768;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-5610780 "FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX2 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Degradation of DVL";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome" XP_030032556.2 7 Reactome: R-HSA-5362798;Reactome: R-HSA-5635838;Reactome: R-HSA-373080;Reactome: R-HSA-5358346;Reactome: R-HSA-5658034;Reactome: R-HSA-5632684;Reactome: R-HSA-5632681 "Release of Hh-Np from the secreting cell";"Activation of SMO";"Class B/2 (Secretin family receptors)";"Hedgehog ligand biogenesis";"HHAT G278V abrogates palmitoylation of Hh-Np";"Hedgehog 'on' state";"Ligand-receptor interactions" XP_030038405.2 3 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.14;Reactome: R-HSA-379726 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_037297975.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037294710.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037302161.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037299280.1 7 MetaCyc: PWY-6737;Reactome: R-HSA-6798695;MetaCyc: PWY-6724;Reactome: R-HSA-70221;MetaCyc: PWY-7238;MetaCyc: PWY-5941;KEGG: 00500+2.4.1.25 "Starch degradation V";"Neutrophil degranulation";"Starch degradation II";"Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II";"Glycogen degradation II";"Starch and sucrose metabolism" XP_030021204.1 16 Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72689 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits" XP_030031872.2 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037293499.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_037292202.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_030027211.2 8 MetaCyc: PWY-5651;MetaCyc: PWY-7733;KEGG: 00380+3.5.1.9;MetaCyc: PWY-6309;KEGG: 00630+3.5.1.9;MetaCyc: PWY-7734;MetaCyc: PWY-7717;MetaCyc: PWY-7765 "L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxyquinaldate biosynthesis";"Tryptophan metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glyoxylate and dicarboxylate metabolism";"Quinoxaline-2-carboxylate biosynthesis";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"3-hydroxy-4-methyl-anthranilate biosynthesis II" XP_037297711.1 4 Reactome: R-HSA-186763;Reactome: R-HSA-373753;Reactome: R-HSA-4420097;Reactome: R-HSA-428540 "Downstream signal transduction";"Nephrin family interactions";"VEGFA-VEGFR2 Pathway";"Activation of RAC1" XP_030035184.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_030041118.1 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" XP_037295693.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030024126.2 11 MetaCyc: PWY-6964;Reactome: R-HSA-8964539;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6549;Reactome: R-HSA-210455;KEGG: 00220+6.3.1.2;KEGG: 00250+6.3.1.2;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6963;MetaCyc: PWY-381;MetaCyc: PWY-5675 "Ammonia assimilation cycle II";"Glutamate and glutamine metabolism";"Nitrogen metabolism";"L-glutamine biosynthesis III";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle I";"Nitrate reduction II (assimilatory)";"Nitrate reduction V (assimilatory)" XP_037301333.1 5 Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-983170 "Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" XP_037295173.1 13 MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;Reactome: R-HSA-2024101;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822 "Chitin degradation II (Vibrio)";"Other glycan degradation";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"CS/DS degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)" XP_037296325.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" XP_030021958.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030030806.2 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_030040449.1 58 Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-174154;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-5689901;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-8939236;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5658442 "Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"APC/C:Cdc20 mediated degradation of Securin";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Metalloprotease DUBs";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs" XP_037302142.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_037293863.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_030025988.2 2 Reactome: R-HSA-5689880;Reactome: R-HSA-8949215 "Ub-specific processing proteases";"Mitochondrial calcium ion transport" XP_030029464.2 6 KEGG: 04660+3.1.3.16;Reactome: R-HSA-8939211;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5693565;Reactome: R-HSA-5675221 "T cell receptor signaling pathway";"ESR-mediated signaling";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Negative regulation of MAPK pathway" XP_030032070.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_030033639.1 3 MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217 "Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage" XP_030035711.2 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037300954.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_030032669.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_037292620.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_030038421.2 5 Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73772 "RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape" XP_037293057.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037300438.1 32 Reactome: R-HSA-167161;Reactome: R-HSA-167287;Reactome: R-HSA-72165;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-6803529;Reactome: R-HSA-168325;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-77075;Reactome: R-HSA-72203;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-8851708;Reactome: R-HSA-167162;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-167243;Reactome: R-HSA-9018519 "HIV Transcription Initiation";"HIV elongation arrest and recovery";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"FGFR2 alternative splicing";"Viral Messenger RNA Synthesis";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II HIV Promoter Escape";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated HIV elongation arrest and recovery";"Estrogen-dependent gene expression" XP_037300265.1 14 MetaCyc: PWY-7587;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7589;Reactome: R-HSA-1483166;MetaCyc: PWY-7782 "Oleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Plasmalogen biosynthesis" XP_030029677.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037299129.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035 "Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"(9Z)-tricosene biosynthesis" XP_037294334.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_037301101.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_037295069.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_030030797.2 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_030041009.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037296928.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_030027078.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664 "Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation" XP_030038540.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_030034835.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" XP_037301542.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_030021840.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_037293642.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_037296637.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_030029338.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_030029644.2 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_037297997.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_030026575.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030032531.1 7 MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897;KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-210500;KEGG: 00250+3.5.1.2 "Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis";"TP53 Regulates Metabolic Genes";"D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"Glutamate Neurotransmitter Release Cycle";"Alanine, aspartate and glutamate metabolism" XP_030033360.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030025250.2 2 Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_037302963.1 6 Reactome: R-HSA-75955;Reactome: R-HSA-5632684;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-201722 "RNA Polymerase II Transcription Elongation";"Hedgehog 'on' state";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of the beta-catenin:TCF transactivating complex" XP_030020182.1 8 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Signaling by Hippo";"Thermogenesis";"Human cytomegalovirus infection" XP_030029361.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_030037202.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_030030324.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_030038923.2 6 Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-429958 "Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease" XP_030028401.1 13 Reactome: R-HSA-2243919;Reactome: R-HSA-419037;Reactome: R-HSA-3000171;Reactome: R-HSA-1442490;Reactome: R-HSA-2214320;Reactome: R-HSA-2022090;Reactome: R-HSA-3000157;Reactome: R-HSA-8948216;Reactome: R-HSA-1474244;Reactome: R-HSA-216083;Reactome: R-HSA-1650814;Reactome: R-HSA-186797;Reactome: R-HSA-3000178 "Crosslinking of collagen fibrils";"NCAM1 interactions";"Non-integrin membrane-ECM interactions";"Collagen degradation";"Anchoring fibril formation";"Assembly of collagen fibrils and other multimeric structures";"Laminin interactions";"Collagen chain trimerization";"Extracellular matrix organization";"Integrin cell surface interactions";"Collagen biosynthesis and modifying enzymes";"Signaling by PDGF";"ECM proteoglycans" XP_030033409.1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_037299874.1 19 Reactome: R-HSA-8963888;Reactome: R-HSA-8964038;Reactome: R-HSA-8856828;Reactome: R-HSA-381426;Reactome: R-HSA-3000480;Reactome: R-HSA-8957275;Reactome: R-HSA-8964041;Reactome: R-HSA-8964026;Reactome: R-HSA-8963901;Reactome: R-HSA-202733;Reactome: R-HSA-3000497;Reactome: R-HSA-8866423;Reactome: R-HSA-3000471;Reactome: R-HSA-5686938;Reactome: R-HSA-8856825;Reactome: R-HSA-3000484;Reactome: R-HSA-8964046;Reactome: R-HSA-975634;Reactome: R-HSA-432142 "Chylomicron assembly";"LDL clearance";"Clathrin-mediated endocytosis";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class A Receptors";"Post-translational protein phosphorylation";"LDL remodeling";"Chylomicron clearance";"Chylomicron remodeling";"Cell surface interactions at the vascular wall";"Scavenging by Class H Receptors";"VLDL assembly";"Scavenging by Class B Receptors";"Regulation of TLR by endogenous ligand";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class F Receptors";"VLDL clearance";"Retinoid metabolism and transport";"Platelet sensitization by LDL" XP_030020079.2 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_030022167.1 3 Reactome: R-HSA-8856828;Reactome: R-HSA-8854214;Reactome: R-HSA-8875656 "Clathrin-mediated endocytosis";"TBC/RABGAPs";"MET receptor recycling" XP_030028393.1 17 Reactome: R-HSA-1362300;Reactome: R-HSA-2559580;Reactome: R-HSA-2173796;Reactome: R-HSA-8953750;Reactome: R-HSA-9616222;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-69231;Reactome: R-HSA-1912408;Reactome: R-HSA-1538133;Reactome: R-HSA-111448;Reactome: R-HSA-2559585;Reactome: R-HSA-69656;Reactome: R-HSA-113501;Reactome: R-HSA-6804114;Reactome: R-HSA-1362277;Reactome: R-HSA-139915 "Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Oxidative Stress Induced Senescence";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcriptional Regulation by E2F6";"Transcriptional regulation of granulopoiesis";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Cyclin D associated events in G1";"Pre-NOTCH Transcription and Translation";"G0 and Early G1";"Activation of NOXA and translocation to mitochondria";"Oncogene Induced Senescence";"Cyclin A:Cdk2-associated events at S phase entry";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcription of E2F targets under negative control by DREAM complex";"Activation of PUMA and translocation to mitochondria" XP_030020439.2 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_037295548.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037295840.1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_030030623.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_030041213.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_030022258.2 8 Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68827 "E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex" XP_030020102.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030031467.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_030027197.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_030034690.2 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_037302291.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_037302872.1 4 MetaCyc: PWY-4841;Reactome: R-HSA-1855183;KEGG: 00562+1.13.99.1;KEGG: 00053+1.13.99.1 "UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Ascorbate and aldarate metabolism" XP_030041326.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_030041095.1 3 MetaCyc: PWY-5129;KEGG: 00600+1.14.19.17;Reactome: R-HSA-1660661 "Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism";"Sphingolipid de novo biosynthesis" XP_037298523.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030023285.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037292277.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_030031564.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_037302611.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556 "Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes" XP_030021773.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_030033392.1 3 MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757 "Folate polyglutamylation";"Folate biosynthesis";"Metabolism of folate and pterines" XP_030027758.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037298610.1 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" XP_030040680.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_030022679.1 4 MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2;Reactome: R-HSA-73817;KEGG: 00230+6.3.5.2 "Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism" XP_037295619.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037299932.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_030024425.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037301800.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_030028517.1 4 Reactome: R-HSA-209931;KEGG: 00790+1.14.16.4;MetaCyc: PWY-6030;KEGG: 00380+1.14.16.4 "Serotonin and melatonin biosynthesis";"Folate biosynthesis";"Serotonin and melatonin biosynthesis";"Tryptophan metabolism" XP_030025905.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_030028000.1 22 MetaCyc: PWY-6598;Reactome: R-HSA-75876;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7053;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7726;MetaCyc: PWY-7035;MetaCyc: PWY-7727;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7606;MetaCyc: PWY-7725;MetaCyc: PWY-7728;MetaCyc: PWY-7592;MetaCyc: PWY-6958;MetaCyc: PWY-7036;MetaCyc: PWY-7049;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-5353 "Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(9Z)-tricosene biosynthesis";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)" XP_030031404.1 5 Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-6783310 "HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Fanconi Anemia Pathway" XP_030027239.1 20 Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-176187;Reactome: R-HSA-6782210;Reactome: R-HSA-69091;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5696397 "Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER" XP_030021486.1 16 Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-8853884;Reactome: R-HSA-174048;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-141430 "Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex" XP_037300778.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_030035578.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_037301249.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-1663150 "Glycosphingolipid metabolism";"The activation of arylsulfatases" XP_037300336.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_037297417.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030040645.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_030022415.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_030032187.1 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_030022796.1 3 Reactome: R-HSA-2022854;Reactome: R-HSA-5173105;Reactome: R-HSA-5083627 "Keratan sulfate biosynthesis";"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6" XP_030025079.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_037293935.1 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" XP_037299351.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037295584.1 10 KEGG: 00562+2.7.1.153;KEGG: 05170+2.7.1.153;KEGG: 04151+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 05165+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 04150+2.7.1.153;MetaCyc: PWY-6352;KEGG: 04070+2.7.1.153;KEGG: 05163+2.7.1.153 "Inositol phosphate metabolism";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Synthesis of PIPs at the plasma membrane";"Human papillomavirus infection";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"mTOR signaling pathway";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Human cytomegalovirus infection" XP_030022307.1 5 Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390450 "Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC" XP_030019698.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_030038733.1 11 Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-163359 "PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Purine metabolism";"PKA activation";"G alpha (s) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation" XP_030030448.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030033700.1 56 Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-9020702;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-8941858 "Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Interleukin-1 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity" XP_037302312.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_030028197.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_030020866.1 17 MetaCyc: PWY-7187;MetaCyc: PWY-7227;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7220;MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7198;MetaCyc: PWY-7221;MetaCyc: PWY-7210;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7197;MetaCyc: PWY-7176;MetaCyc: PWY-7222;MetaCyc: PWY-7205;KEGG: 00240+2.7.4.6 "Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotide phosphorylation";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Pyrimidine metabolism" XP_037298980.1 7 MetaCyc: PWY-6367;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351 "D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis" XP_037297590.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening" XP_037300199.1 5 Reactome: R-HSA-1912408;Reactome: R-HSA-1912420;Reactome: R-HSA-350054;Reactome: R-HSA-5083630;Reactome: R-HSA-1912399 "Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in Golgi";"Notch-HLH transcription pathway";"Defective LFNG causes SCDO3";"Pre-NOTCH Processing in the Endoplasmic Reticulum" XP_037294182.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380320 "Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes" XP_030022273.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037299264.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030036367.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_030031638.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037294812.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037298585.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_030031999.1 5 KEGG: 04150+2.7.11.24;Reactome: R-HSA-4420097;Reactome: R-HSA-376172;Reactome: R-HSA-171007;Reactome: R-HSA-168638 "mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"DSCAM interactions";"p38MAPK events";"NOD1/2 Signaling Pathway" XP_030031633.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037301703.1 2 Reactome: R-HSA-1663150;Reactome: R-HSA-1660662 "The activation of arylsulfatases";"Glycosphingolipid metabolism" XP_030023824.2 6 MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;Reactome: R-HSA-913709 "Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins" XP_030037262.2 4 MetaCyc: PWY-5188;Reactome: R-HSA-189451;KEGG: 00860+4.2.1.75;MetaCyc: PWY-5189 "Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)" XP_030024435.2 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_030021144.1 2 Reactome: R-HSA-5576886;Reactome: R-HSA-1299308 "Phase 4 - resting membrane potential";"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)" XP_030026447.2 27 Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-180746 "SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein" XP_037295071.1 3 Reactome: R-HSA-1660517;Reactome: R-HSA-1660514;Reactome: R-HSA-1660516 "Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane" XP_030036487.2 3 Reactome: R-HSA-162658;Reactome: R-HSA-6807878;Reactome: R-HSA-204005 "Golgi Cisternae Pericentriolar Stack Reorganization";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport" XP_030035189.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_037292371.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_037296717.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_030021415.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037299054.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_030029365.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_030037989.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037300766.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_030022643.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030027356.1 5 KEGG: 00330+1.14.13.39;Reactome: R-HSA-1222556;MetaCyc: PWY-4983;KEGG: 00220+1.14.13.39;Reactome: R-HSA-392154 "Arginine and proline metabolism";"ROS and RNS production in phagocytes";"Nitric oxide biosynthesis II (mammals)";"Arginine biosynthesis";"Nitric oxide stimulates guanylate cyclase" XP_030021625.1 26 Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-389977;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-389960;Reactome: R-HSA-9648025;Reactome: R-HSA-983189 "Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"HCMV Early Events";"Cilium Assembly";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"Post-chaperonin tubulin folding pathway";"Aggrephagy";"Mitotic Prometaphase";"Recycling pathway of L1";"Formation of tubulin folding intermediates by CCT/TriC";"EML4 and NUDC in mitotic spindle formation";"Kinesins" XP_030033718.1 7 Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606 "Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_037298260.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_037295994.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037293615.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_030021137.1 8 KEGG: 05170+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"Signaling by Hippo";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_037295318.1 2 Reactome: R-HSA-5673001;Reactome: R-HSA-8853659 "RAF/MAP kinase cascade";"RET signaling" XP_030020040.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037302531.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037292978.1 5 MetaCyc: PWY-7268;MetaCyc: PWY-7269;MetaCyc: PWY-5083;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism" XP_030031973.2 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_030030458.1 2 Reactome: R-HSA-162588;Reactome: R-HSA-917729 "Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_030035219.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394 "Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER" XP_030037786.2 15 Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-2559585;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398 "Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Oncogene Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway" XP_030029557.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport" XP_030026786.2 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_030020547.1 4 MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17;KEGG: 00790+4.1.99.22 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Folate biosynthesis" XP_030039194.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_030037393.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_030041138.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_030021918.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_030022843.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_030025035.1 13 Reactome: R-HSA-3928663;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3928662;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-5627117;Reactome: R-HSA-4420097;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "EPHA-mediated growth cone collapse";"Relaxin signaling pathway";"G alpha (12/13) signalling events";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"EPHB-mediated forward signaling";"Human papillomavirus infection";"Sema4D induced cell migration and growth-cone collapse";"RHO GTPases Activate ROCKs";"VEGFA-VEGFR2 Pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis" XP_030040229.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_030027938.1 11 MetaCyc: PWY-6608;MetaCyc: PWY-6596;KEGG: 00230+3.1.3.5;MetaCyc: PWY-5381;MetaCyc: PWY-5695;KEGG: 00760+3.1.3.5;MetaCyc: PWY-6607;MetaCyc: PWY-7821;MetaCyc: PWY-7185;KEGG: 00240+3.1.3.5;MetaCyc: PWY-6606 "Guanosine nucleotides degradation III";"Adenosine nucleotides degradation I";"Purine metabolism";"Pyridine nucleotide cycling (plants)";"Inosine 5'-phosphate degradation";"Nicotinate and nicotinamide metabolism";"Guanosine nucleotides degradation I";"Tunicamycin biosynthesis";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism";"Guanosine nucleotides degradation II" XP_030033600.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_030035422.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037294250.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_030035276.1 27 Reactome: R-HSA-159230;Reactome: R-HSA-72187;Reactome: R-HSA-72165;Reactome: R-HSA-72203;Reactome: R-HSA-167200;Reactome: R-HSA-159227;Reactome: R-HSA-77588;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-8851708;Reactome: R-HSA-9010553;Reactome: R-HSA-159231;Reactome: R-HSA-6803529;Reactome: R-HSA-167152;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72086;Reactome: R-HSA-77595;Reactome: R-HSA-111367;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-167158;Reactome: R-HSA-6807505 "Transport of the SLBP Dependant Mature mRNA";"mRNA 3'-end processing";"mRNA Splicing - Minor Pathway";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transport of the SLBP independent Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"Signaling by FGFR2 IIIa TM";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA Derived from an Intronless Transcript";"FGFR2 alternative splicing";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"mRNA Capping";"Processing of Intronless Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes" XP_030039873.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_030032997.2 4 Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange" XP_030023902.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_030030484.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_030024178.2 4 Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-382556 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport" XP_030020315.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-5689880 "HATs acetylate histones";"Ub-specific processing proteases" XP_037302074.1 2 Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_037292837.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037294556.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_037303015.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_030033166.1 17 MetaCyc: PWY-7179;MetaCyc: PWY-6644;MetaCyc: PWY-5532;MetaCyc: PWY-6608;MetaCyc: PWY-5695;MetaCyc: PWY-6627;MetaCyc: PWY-7179-1;Reactome: R-HSA-6798695;MetaCyc: PWY-6609;Reactome: R-HSA-74217;MetaCyc: PWY-6611;Reactome: R-HSA-74259;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6620;KEGG: 00760+2.4.2.1;KEGG: 00240+2.4.2.1;MetaCyc: PWY-4202 "Purine deoxyribonucleosides degradation I";"Fluoroacetate and fluorothreonine biosynthesis";"Nucleoside and nucleotide degradation (archaea)";"Guanosine nucleotides degradation III";"Inosine 5'-phosphate degradation";"Salinosporamide A biosynthesis";"Purine deoxyribonucleosides degradation II";"Neutrophil degranulation";"Adenine and adenosine salvage III";"Purine salvage";"Adenine and adenosine salvage V";"Purine catabolism";"Purine metabolism";"Guanine and guanosine salvage";"Nicotinate and nicotinamide metabolism";"Pyrimidine metabolism";"Arsenate detoxification I (mammalian)" XP_037292806.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_030028496.1 3 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109 "Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis" XP_030030939.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_030025999.2 20 KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-166208;KEGG: 05163+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-5628897;KEGG: 04151+2.7.11.1;Reactome: R-HSA-8943724;Reactome: R-HSA-6804757;Reactome: R-HSA-1632852;Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-1257604 "Human immunodeficiency virus 1 infection";"Constitutive Signaling by AKT1 E17K in Cancer";"mTORC1-mediated signalling";"Human cytomegalovirus infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"Thermogenesis";"Relaxin signaling pathway";"VEGFR2 mediated vascular permeability";"TP53 Regulates Metabolic Genes";"PI3K-Akt signaling pathway";"Regulation of PTEN gene transcription";"Regulation of TP53 Degradation";"Macroautophagy";"HSF1-dependent transactivation";"mTOR signalling";"Amino acids regulate mTORC1";"mTOR signaling pathway";"Human papillomavirus infection";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling" XP_037297375.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_037299580.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_030022260.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030022261.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037298896.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_030036918.1 3 Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-8939243 "Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_037301910.1 7 MetaCyc: PWY-6124;MetaCyc: PWY-7234;Reactome: R-HSA-73817;KEGG: 00250+4.3.2.2;MetaCyc: PWY-6123;KEGG: 00230+4.3.2.2;MetaCyc: PWY-7219 "Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_037302488.1 32 Reactome: R-HSA-167243;Reactome: R-HSA-9018519;Reactome: R-HSA-167160;Reactome: R-HSA-167162;Reactome: R-HSA-8851708;Reactome: R-HSA-72163;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-77075;Reactome: R-HSA-72203;Reactome: R-HSA-167200;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-6803529;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-168325;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-76042;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-72165;Reactome: R-HSA-75953;Reactome: R-HSA-167287 "Tat-mediated HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II HIV Promoter Escape";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Major Pathway";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Viral Messenger RNA Synthesis";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation";"HIV elongation arrest and recovery" XP_030036909.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_030027999.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9010553 "SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs" XP_030028202.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_030029581.2 6 KEGG: 00730+2.7.6.2;MetaCyc: PWY-6908;MetaCyc: PWY-7356;MetaCyc: PWY-6898;Reactome: R-HSA-196819;MetaCyc: PWY-6907 "Thiamine metabolism";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine salvage IV (yeast)";"Thiamine salvage III";"Vitamin B1 (thiamin) metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)" XP_030040318.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_037293705.1 3 KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420 "Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)" XP_030020267.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_030021421.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912 "Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane" XP_037295871.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_030023492.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_037301058.1 2 Reactome: R-HSA-1221632;Reactome: R-HSA-5601884 "Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis" XP_030037890.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037302474.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism" XP_030041222.1 11 Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-2173796;Reactome: R-HSA-9013695;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-8941856;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-72163;Reactome: R-HSA-350054 "Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"mRNA Splicing - Major Pathway";"Notch-HLH transcription pathway" XP_037302605.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_030026833.1 9 MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7115;Reactome: R-HSA-1475029;MetaCyc: PWY-5743 "3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate cycle" XP_030036660.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030028910.1 4 Reactome: R-HSA-3899300;Reactome: R-HSA-9613829;Reactome: R-HSA-9646399;Reactome: R-HSA-9615710 "SUMOylation of transcription cofactors";"Chaperone Mediated Autophagy";"Aggrephagy";"Late endosomal microautophagy" XP_030029212.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_030038245.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-8949215 "Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport" XP_030020137.2 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_030025010.1 7 KEGG: 00240+2.4.2.10;KEGG: 00983+2.4.2.10;MetaCyc: PWY-5686;Reactome: R-HSA-500753;MetaCyc: PWY-7791;MetaCyc: PWY-7790;KEGG: 00240+4.1.1.23 "Pyrimidine metabolism";"Drug metabolism - other enzymes";"UMP biosynthesis I";"Pyrimidine biosynthesis";"UMP biosynthesis III";"UMP biosynthesis II";"Pyrimidine metabolism" XP_030027126.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_037293711.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73776 "Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape" XP_030019873.2 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_030040644.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_037297947.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_037303442.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_030032859.1 7 Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-73980 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination" XP_030039514.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73776 "Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape" XP_030022531.2 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_037296549.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_030031347.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037296641.1 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" XP_037296237.1 4 Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695 "E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events" XP_030021410.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_030026843.2 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037295541.1 19 Reactome: R-HSA-3000471;Reactome: R-HSA-8866423;Reactome: R-HSA-3000497;Reactome: R-HSA-5686938;Reactome: R-HSA-8856825;Reactome: R-HSA-3000484;Reactome: R-HSA-975634;Reactome: R-HSA-8964046;Reactome: R-HSA-432142;Reactome: R-HSA-8963888;Reactome: R-HSA-8856828;Reactome: R-HSA-8964038;Reactome: R-HSA-381426;Reactome: R-HSA-3000480;Reactome: R-HSA-8957275;Reactome: R-HSA-8964041;Reactome: R-HSA-8963901;Reactome: R-HSA-8964026;Reactome: R-HSA-202733 "Scavenging by Class B Receptors";"VLDL assembly";"Scavenging by Class H Receptors";"Regulation of TLR by endogenous ligand";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class F Receptors";"Retinoid metabolism and transport";"VLDL clearance";"Platelet sensitization by LDL";"Chylomicron assembly";"Clathrin-mediated endocytosis";"LDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class A Receptors";"Post-translational protein phosphorylation";"LDL remodeling";"Chylomicron remodeling";"Chylomicron clearance";"Cell surface interactions at the vascular wall" XP_030020941.1 2 MetaCyc: PWY-7800;MetaCyc: PWY-7799 "Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)" XP_030032184.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_037300451.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-162588 "Late endosomal microautophagy";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion" XP_030040854.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_030035273.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037294714.1 13 Reactome: R-HSA-1489509;Reactome: R-HSA-5218921;Reactome: R-HSA-983695;Reactome: R-HSA-422356;Reactome: R-HSA-112043;Reactome: R-HSA-2029485;Reactome: R-HSA-139853;Reactome: R-HSA-114508;Reactome: R-HSA-381676;Reactome: R-HSA-4086398;Reactome: R-HSA-5578775;Reactome: R-HSA-2871809;Reactome: R-HSA-5607763 "DAG and IP3 signaling";"VEGFR2 mediated cell proliferation";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Regulation of insulin secretion";"PLC beta mediated events";"Role of phospholipids in phagocytosis";"Elevation of cytosolic Ca2+ levels";"Effects of PIP2 hydrolysis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway";"Ion homeostasis";"FCERI mediated Ca+2 mobilization";"CLEC7A (Dectin-1) induces NFAT activation" XP_030021445.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_037297949.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression" XP_030027562.2 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_037300403.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_030025443.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_030039854.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_030036488.2 3 Reactome: R-HSA-6807878;Reactome: R-HSA-162658;Reactome: R-HSA-204005 "COPI-mediated anterograde transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPII-mediated vesicle transport" XP_037294445.1 2 Reactome: R-HSA-5673001;Reactome: R-HSA-8853659 "RAF/MAP kinase cascade";"RET signaling" XP_030020852.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_030040873.1 3 Reactome: R-HSA-6806664;KEGG: 00130+1.17.4.4;MetaCyc: PWY-7999 "Metabolism of vitamin K";"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle" XP_030024314.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_030021167.2 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_030022078.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691 "Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_037299091.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-381038;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-3371497;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380259 "COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"XBP1(S) activates chaperone genes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes" XP_037295073.1 57 Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-8852276;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176 "SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"Hedgehog ligand biogenesis";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha" XP_030022488.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037293471.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway" XP_030035733.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_030022083.1 11 Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418555 "Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"PKA activation";"Purine metabolism";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (s) signalling events" XP_030019805.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes" XP_037293398.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_037293518.1 16 Reactome: R-HSA-9018519;Reactome: R-HSA-3214847;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693548;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-6804756 "Estrogen-dependent gene expression";"HATs acetylate histones";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Sensing of DNA Double Strand Breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Activity through Phosphorylation" XP_030037533.1 4 Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169 "Translesion synthesis by POLI";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis" XP_030027512.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_030025203.1 3 KEGG: 00480+4.3.2.9;MetaCyc: PWY-4041;Reactome: R-HSA-174403 "Glutathione metabolism";"Gamma-glutamyl cycle";"Glutathione synthesis and recycling" XP_030034759.2 8 MetaCyc: PWY-7573;KEGG: 00520+4.2.1.47;Reactome: R-HSA-6787639;MetaCyc: PWY-5738;KEGG: 00051+4.2.1.47;MetaCyc: PWY-66;MetaCyc: PWY-5739;MetaCyc: PWY-5740 "GDP-mycosamine biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis";"GDP-6-deoxy-D-talose biosynthesis";"Fructose and mannose metabolism";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-D-perosamine biosynthesis";"GDP-L-colitose biosynthesis" XP_037292677.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037300033.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_030029648.2 2 KEGG: 00290+4.3.1.19;KEGG: 00260+4.3.1.19 "Valine, leucine and isoleucine biosynthesis";"Glycine, serine and threonine metabolism" XP_030024546.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037294590.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037297193.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518 "Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2" XP_037297976.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_030031375.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_037294946.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_030032962.1 2 Reactome: R-HSA-196819;KEGG: 00230+4.6.1.1 "Vitamin B1 (thiamin) metabolism";"Purine metabolism" XP_030020300.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030037054.1 4 Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878 "NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport" XP_030031184.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030034466.2 4 Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395 "Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER" XP_030037506.2 1 Reactome: R-HSA-110357 "Displacement of DNA glycosylase by APEX1" XP_030020597.1 3 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901;Reactome: R-HSA-8951664 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol";"Neddylation" XP_037293620.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_037303284.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_030032066.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030040937.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_030028304.2 6 KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-2221;KEGG: 00030+3.1.1.17;KEGG: 00930+3.1.1.17;MetaCyc: PWY-5530 "Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pentose phosphate pathway";"Caprolactam degradation";"Sorbitol biosynthesis II" XP_037299375.1 6 Reactome: R-HSA-9609690;Reactome: R-HSA-9022692;Reactome: R-HSA-9022537;Reactome: R-HSA-3214815;Reactome: R-HSA-1989781;Reactome: R-HSA-9029569 "HCMV Early Events";"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"HDACs deacetylate histones";"PPARA activates gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_037294947.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_030031607.2 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037297908.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037294272.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661 "Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis" XP_030033171.1 3 MetaCyc: PWY-6689;MetaCyc: PWY-7803;Reactome: R-HSA-6784531 "Trna splicing I";"Trna splicing II";"tRNA processing in the nucleus" XP_030023822.2 6 Reactome: R-HSA-5083632;Reactome: R-HSA-913709;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122 "Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis" XP_037299399.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030029558.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling" XP_030032031.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_030040884.2 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037295901.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_030028129.2 15 MetaCyc: PWY-2221;MetaCyc: PWY-8004;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-6142;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-7003;MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-6886;MetaCyc: PWY-5723 "Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Glycolysis";"Purine metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Rubisco shunt" XP_037302046.1 1 Reactome: R-HSA-8849175 "Threonine catabolism" XP_030039508.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-73779 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_037292215.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037293507.1 7 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_037297907.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_030020042.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037300979.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_030020101.2 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037303484.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_030038594.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_030026817.2 3 Reactome: R-HSA-194313;Reactome: R-HSA-195399;Reactome: R-HSA-114608 "VEGF ligand-receptor interactions";"VEGF binds to VEGFR leading to receptor dimerization";"Platelet degranulation" XP_037300550.1 6 KEGG: 00230+4.1.1.21;MetaCyc: PWY-6123;KEGG: 00230+6.3.2.6;MetaCyc: PWY-7234;MetaCyc: PWY-6124;Reactome: R-HSA-73817 "Purine metabolism";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis" XP_030035509.2 56 Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-69601;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-8939902;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX2 expression and activity";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins" XP_030036880.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_030028648.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_030020398.2 6 Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556 "Neutrophil degranulation";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes" XP_030028467.1 5 KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22 "Galactose metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Glycerolipid metabolism" XP_030029396.2 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway" XP_037294305.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_037298580.1 5 KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;Reactome: R-HSA-197264;MetaCyc: PWY-5381 "Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)" XP_030034788.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827 "Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_037292260.1 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_030025643.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030037136.1 7 Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-6798695;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-5620922 "Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Neutrophil degranulation";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium" XP_030021765.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_037292657.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037297745.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_030020003.1 13 Reactome: R-HSA-156590;KEGG: 00980+2.5.1.18;Reactome: R-HSA-196836;KEGG: 00053+1.8.5.1;KEGG: 00983+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-7533;MetaCyc: PWY-6842;MetaCyc: PWY-6370;MetaCyc: PWY-7112;KEGG: 00982+2.5.1.18;MetaCyc: PWY-2261;KEGG: 00480+2.5.1.18+1.8.5.1 "Glutathione conjugation";"Metabolism of xenobiotics by cytochrome P450";"Vitamin C (ascorbate) metabolism";"Ascorbate and aldarate metabolism";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification II";"Ascorbate recycling (cytosolic)";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - cytochrome P450";"Ascorbate glutathione cycle";"Glutathione metabolism" XP_037299484.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037300436.1 4 KEGG: 00510+2.4.1.259+2.4.1.261;KEGG: 00513+2.4.1.261;Reactome: R-HSA-446193;Reactome: R-HSA-4720454 "N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG9 causes ALG9-CDG (CDG-1l)" XP_037303375.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037303642.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_030026824.1 5 Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-1445148 "RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_037300269.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_037297524.1 1 Reactome: R-HSA-203754 "NOSIP mediated eNOS trafficking" XP_030038297.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_030022382.1 6 Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs" XP_037297548.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_030034806.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_030032739.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_030024746.1 4 Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_030026189.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_030027347.1 4 KEGG: 00785+2.8.1.8;MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-389661 "Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation" XP_030040905.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_030029944.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_030036967.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_037302802.1 56 Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-69601;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-8939902;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-180585;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837 "Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX2 expression and activity";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation" XP_037299901.1 2 MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24 "Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis" XP_037292846.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" YP_001650754.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_030035254.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_037294413.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606 "NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_030031769.1 7 MetaCyc: PWY-5469;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5466 "Sesamin biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Matairesinol biosynthesis" XP_037297028.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030022507.2 8 Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-9627069;Reactome: R-HSA-6803207;Reactome: R-HSA-111463;Reactome: R-HSA-6798695;Reactome: R-HSA-8953750;Reactome: R-HSA-111464 "Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"Regulation of the apoptosome activity";"TP53 Regulates Transcription of Caspase Activators and Caspases";"SMAC (DIABLO) binds to IAPs";"Neutrophil degranulation";"Transcriptional Regulation by E2F6";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes" XP_037301670.1 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" XP_037295205.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" XP_030028522.2 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037292676.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037298365.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_030038402.2 5 MetaCyc: PWY-5381;Reactome: R-HSA-197264;KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108 "Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_037299473.1 5 Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2 "Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism" XP_037296636.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_037303055.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_030027627.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_030027458.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037295650.1 3 MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21 "Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system" XP_037295379.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037293611.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037299914.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037303281.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_030020078.2 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_037299653.1 4 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000178 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions";"ECM proteoglycans" XP_030037836.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037299133.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_037299471.1 5 Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084 "Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_037300757.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_037294460.1 13 KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674135;Reactome: R-HSA-6802952;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-6802948;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6802946;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Signaling by high-kinase activity BRAF mutants";"PI3K-Akt signaling pathway";"Signaling by moderate kinase activity BRAF mutants";"Human papillomavirus infection" XP_037295519.1 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" XP_030035931.2 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_030030460.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-162588 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion" XP_030029499.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_030037387.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72695 "Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex" XP_030033888.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037298368.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037298331.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_030031028.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037294005.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037294317.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_030035032.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-73980 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination" XP_030032637.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_037298090.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037303201.1 42 Reactome: R-HSA-110328;Reactome: R-HSA-110330;Reactome: R-HSA-4551638;Reactome: R-HSA-3214847;Reactome: R-HSA-171306;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-977225;Reactome: R-HSA-1221632;Reactome: R-HSA-3214815;Reactome: R-HSA-3214841;Reactome: R-HSA-5693607;Reactome: R-HSA-3214842;Reactome: R-HSA-2559586;Reactome: R-HSA-201722;Reactome: R-HSA-110331;Reactome: R-HSA-110329;Reactome: R-HSA-212300;Reactome: R-HSA-9616222;Reactome: R-HSA-5693565;Reactome: R-HSA-73728;Reactome: R-HSA-2299718;Reactome: R-HSA-8939236;Reactome: R-HSA-5250924;Reactome: R-HSA-9018519;Reactome: R-HSA-427359;Reactome: R-HSA-5625886;Reactome: R-HSA-912446;Reactome: R-HSA-3214858;Reactome: R-HSA-9610379;Reactome: R-HSA-5334118;Reactome: R-HSA-2559582;Reactome: R-HSA-8936459;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-1912408;Reactome: R-HSA-9609690;Reactome: R-HSA-427389;Reactome: R-HSA-73772;Reactome: R-HSA-69473;Reactome: R-HSA-606279;Reactome: R-HSA-5693571 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"SUMOylation of chromatin organization proteins";"HATs acetylate histones";"Packaging Of Telomere Ends";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Amyloid fiber formation";"Meiotic synapsis";"HDACs deacetylate histones";"PKMTs methylate histone lysines";"Processing of DNA double-strand break ends";"HDMs demethylate histones";"DNA Damage/Telomere Stress Induced Senescence";"Formation of the beta-catenin:TCF transactivating complex";"Cleavage of the damaged purine";"Cleavage of the damaged pyrimidine";"PRC2 methylates histones and DNA";"Transcriptional regulation of granulopoiesis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RNA Polymerase I Promoter Opening";"Condensation of Prophase Chromosomes";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"B-WICH complex positively regulates rRNA expression";"Estrogen-dependent gene expression";"SIRT1 negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Meiotic recombination";"RMTs methylate histone arginines";"HCMV Late Events";"DNA methylation";"Senescence-Associated Secretory Phenotype (SASP)";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"Pre-NOTCH Transcription and Translation";"HCMV Early Events";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Escape";"G2/M DNA damage checkpoint";"Deposition of new CENPA-containing nucleosomes at the centromere";"Nonhomologous End-Joining (NHEJ)" XP_030029111.1 5 MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6902;Reactome: R-HSA-189085 "Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate" XP_030022057.2 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_037294571.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037292728.1 27 Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-4615885;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142 "Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA replication proteins";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins" XP_030027457.1 7 Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724 "mTOR signalling";"mTORC1-mediated signalling";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription" XP_037298258.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_030041076.2 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_030026597.1 5 Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-9630222;Reactome: R-HSA-9630221;Reactome: R-HSA-110357 "Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective NTHL1 substrate binding";"Defective NTHL1 substrate processing";"Displacement of DNA glycosylase by APEX1" XP_030027532.1 5 Reactome: R-HSA-6783310;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400 "Fanconi Anemia Pathway";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER" XP_037296212.1 4 Reactome: R-HSA-1655829;Reactome: R-HSA-8874211;Reactome: R-HSA-381033;Reactome: R-HSA-8963889 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"CREB3 factors activate genes";"ATF6 (ATF6-alpha) activates chaperones";"Assembly of active LPL and LIPC lipase complexes" XP_030023131.1 7 MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-6824 "Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Justicidin B biosynthesis" XP_030023597.2 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_037292323.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_037299034.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_030030664.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_037298270.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_037300216.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037301476.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037300522.1 4 Reactome: R-HSA-936440;Reactome: R-HSA-5205685;Reactome: R-HSA-1632852;Reactome: R-HSA-8934903 "Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy";"Macroautophagy";"Receptor Mediated Mitophagy" XP_037295352.1 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection" XP_030033789.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037300808.1 9 Reactome: R-HSA-8856828;Reactome: R-HSA-9615710;Reactome: R-HSA-8856825;Reactome: R-HSA-9613829;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-5627083;Reactome: R-HSA-9646399;Reactome: R-HSA-5678895 "Clathrin-mediated endocytosis";"Late endosomal microautophagy";"Cargo recognition for clathrin-mediated endocytosis";"Chaperone Mediated Autophagy";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"RHO GTPases regulate CFTR trafficking";"Aggrephagy";"Defective CFTR causes cystic fibrosis" XP_030041127.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_030033352.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037303104.1 3 Reactome: R-HSA-2408508;Reactome: R-HSA-1614603;Reactome: R-HSA-1614558 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine" XP_030025897.1 31 MetaCyc: PWY-5142;MetaCyc: PWY-5989;Reactome: R-HSA-75105;MetaCyc: PWY-5973;MetaCyc: PWY-7858;MetaCyc: PWYG-321;Reactome: R-HSA-2426168;MetaCyc: PWY-7663;MetaCyc: PWY-5366;Reactome: R-HSA-199220;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5147;MetaCyc: PWY-5994;MetaCyc: PWY-5971;MetaCyc: PWY-7388;MetaCyc: PWY-8049;Reactome: R-HSA-9029558;MetaCyc: PWY-7723;MetaCyc: PWY-5367;MetaCyc: PWY-6282;MetaCyc: PWY-6799;MetaCyc: PWY-7664;MetaCyc: PWY-4381;MetaCyc: PWY-6519;Reactome: R-HSA-163765;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8047;MetaCyc: PWY-8012;MetaCyc: PWY-7746;MetaCyc: PWY-5966-1;MetaCyc: PWY-6113 "Acyl-[acyl-carrier protein] thioesterase pathway";"Stearate biosynthesis II (bacteria and plants)";"Fatty acyl-CoA biosynthesis";"Cis-vaccenate biosynthesis";"(5Z)-dodecenoate biosynthesis II";"";"Activation of gene expression by SREBF (SREBP)";"Gondoate biosynthesis (anaerobic)";"Palmitoleate biosynthesis II (plants and bacteria)";"Vitamin B5 (pantothenate) metabolism";"Fatty acid biosynthesis";"Oleate biosynthesis I (plants)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Pederin biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Bacterial bioluminescence";"Petroselinate biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"ChREBP activates metabolic gene expression";"Biotin metabolism";"Bryostatin biosynthesis";"Mupirocin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Superpathway of mycolate biosynthesis" XP_030030217.1 7 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway" XP_030020892.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_030020689.1 2 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol" XP_037298628.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_037300293.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037301818.1 2 MetaCyc: PWY-5697;KEGG: 00230+3.5.3.4 "Allantoin degradation to ureidoglycolate I (urea producing)";"Purine metabolism" XP_037298678.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037303592.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_030032705.2 3 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_030020588.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_037294232.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_030034606.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;MetaCyc: PWY-7511;Reactome: R-HSA-6782210 "mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Protein ubiquitination";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_037297776.1 9 Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-76042 "RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_030028915.1 3 MetaCyc: PWY-5067;Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11 "Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis";"Starch and sucrose metabolism" XP_037292726.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037292945.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes" XP_030027625.1 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" XP_037293672.1 7 Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-8854214;Reactome: R-HSA-165181;Reactome: R-HSA-5674400;Reactome: R-HSA-198323 "Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"TBC/RABGAPs";"Inhibition of TSC complex formation by PKB";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol" XP_030034097.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_030027584.1 14 Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-203927;Reactome: R-HSA-9029569;Reactome: R-HSA-426486;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-426496;Reactome: R-HSA-4086398 "Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"MicroRNA (miRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Small interfering RNA (siRNA) biogenesis";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Post-transcriptional silencing by small RNAs";"Ca2+ pathway" XP_037293903.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_030034374.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037298802.1 11 Reactome: R-HSA-2022928;Reactome: R-HSA-4420332;Reactome: R-HSA-3560783;Reactome: R-HSA-3560801;Reactome: R-HSA-1971475;Reactome: R-HSA-3000170;Reactome: R-HSA-3656253;Reactome: R-HSA-202733;Reactome: R-HSA-2024096;Reactome: R-HSA-3656237;Reactome: R-HSA-975634 "HS-GAG biosynthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GAT3 causes JDSSDHD";"A tetrasaccharide linker sequence is required for GAG synthesis";"Syndecan interactions";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Cell surface interactions at the vascular wall";"HS-GAG degradation";"Defective EXT2 causes exostoses 2";"Retinoid metabolism and transport" XP_037300081.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037301970.1 15 Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-9029569 "Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_037299347.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_030023637.2 12 MetaCyc: PWY-5857;MetaCyc: PWY-5855;MetaCyc: PWY-5870;Reactome: R-HSA-2142789;MetaCyc: PWY-5871;MetaCyc: PWY-7230;MetaCyc: PWY-5873;MetaCyc: PWY-7233;MetaCyc: PWY-5856;MetaCyc: PWY-5872;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-6708 "Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)" XP_030020511.2 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037301610.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030030175.1 5 KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-6902 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)" XP_030019611.1 2 Reactome: R-HSA-204174;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid" XP_037292309.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_030019904.2 8 Reactome: R-HSA-212300;Reactome: R-HSA-3214841;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-9609690;Reactome: R-HSA-5617472;Reactome: R-HSA-8953750;Reactome: R-HSA-4551638 "PRC2 methylates histones and DNA";"PKMTs methylate histone lysines";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"HCMV Early Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional Regulation by E2F6";"SUMOylation of chromatin organization proteins" XP_030034693.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_030022921.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_030034966.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037298986.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_037294501.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_030029491.2 4 Reactome: R-HSA-6802952;Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-983168 "Signaling by BRAF and RAF fusions";"Macroautophagy";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037300274.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6811434 "Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037295124.1 1 Reactome: R-HSA-375276 "Peptide ligand-binding receptors" XP_030024313.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_030020482.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037295180.1 6 MetaCyc: PWY-6722;MetaCyc: PWY-5743;MetaCyc: PWY-4381;MetaCyc: PWY-5789;Reactome: R-HSA-196780;MetaCyc: PWY-5744 "Candicidin biosynthesis";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"Glyoxylate assimilation" XP_030031397.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_037295631.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_030022628.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037301229.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037300435.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_037298837.1 11 MetaCyc: PWY-381;MetaCyc: PWY-5675;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6963;KEGG: 00910+6.3.1.2;Reactome: R-HSA-210455;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6549;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6964;Reactome: R-HSA-8964539 "Nitrate reduction II (assimilatory)";"Nitrate reduction V (assimilatory)";"Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle I";"Nitrogen metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Arginine biosynthesis";"L-glutamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle II";"Glutamate and glutamine metabolism" XP_030035668.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_030040954.1 6 KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085;MetaCyc: PWY-5067 "Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)" XP_030031902.1 2 Reactome: R-HSA-190373;Reactome: R-HSA-5654726 "FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling" XP_037299352.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_030021039.1 8 Reactome: R-HSA-8948747;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-8866652;Reactome: R-HSA-6804757;Reactome: R-HSA-5689880;Reactome: R-HSA-6782210 "Regulation of PTEN localization";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of TP53 Degradation";"Ub-specific processing proteases";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_037299322.1 7 Reactome: R-HSA-201722;Reactome: R-HSA-5696394;Reactome: R-HSA-5689880;Reactome: R-HSA-171319;Reactome: R-HSA-5689603;Reactome: R-HSA-606279;Reactome: R-HSA-3214847 "Formation of the beta-catenin:TCF transactivating complex";"DNA Damage Recognition in GG-NER";"Ub-specific processing proteases";"Telomere Extension By Telomerase";"UCH proteinases";"Deposition of new CENPA-containing nucleosomes at the centromere";"HATs acetylate histones" XP_030020909.1 18 MetaCyc: PWY-6969;KEGG: 00020+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00630+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-7383;KEGG: 00710+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-561;MetaCyc: PWY-5913;MetaCyc: PWY-5690;KEGG: 00620+1.1.1.37;KEGG: 00270+1.1.1.37;Reactome: R-HSA-70263;KEGG: 00680+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-7115 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Formaldehyde assimilation I (serine pathway)";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation in photosynthetic organisms";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glyoxylate cycle and fatty acid degradation";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Pyruvate metabolism";"Cysteine and methionine metabolism";"Gluconeogenesis";"Methane metabolism";"Methylaspartate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" XP_030030230.2 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_037302445.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037294471.1 2 MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24 "Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis" XP_030022162.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_030020074.1 5 Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828 "EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"Clathrin-mediated endocytosis" XP_037292263.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_037294253.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_030023719.2 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_030040196.2 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_030032239.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037301626.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_037298227.1 18 Reactome: R-HSA-912446;Reactome: R-HSA-1221632;Reactome: R-HSA-6796648;Reactome: R-HSA-5689901;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-8953750;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;MetaCyc: PWY-7511;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568 "Meiotic recombination";"Meiotic synapsis";"TP53 Regulates Transcription of DNA Repair Genes";"Metalloprotease DUBs";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Transcriptional Regulation by E2F6";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Protein ubiquitination";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_030021413.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_030034433.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_030028407.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_037303059.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_030033577.2 3 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism" XP_037296497.1 6 Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-434316 "G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion" XP_037298570.1 10 MetaCyc: PWY-7328;Reactome: R-HSA-70370;Reactome: R-HSA-5609977;KEGG: 00520+5.1.3.2;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-6317;MetaCyc: PWY-3821;MetaCyc: PWY-6397;MetaCyc: PWY-6527 "Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose catabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"UDP-alpha-D-galactose biosynthesis";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Stachyose degradation" XP_030028394.1 17 Reactome: R-HSA-111448;Reactome: R-HSA-1538133;Reactome: R-HSA-1912408;Reactome: R-HSA-69231;Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-9616222;Reactome: R-HSA-139915;Reactome: R-HSA-1362277;Reactome: R-HSA-6804114;Reactome: R-HSA-69656;Reactome: R-HSA-113501;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-1362300;Reactome: R-HSA-8953750;Reactome: R-HSA-2173796 "Activation of NOXA and translocation to mitochondria";"G0 and Early G1";"Pre-NOTCH Transcription and Translation";"Cyclin D associated events in G1";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"Transcriptional regulation of granulopoiesis";"Activation of PUMA and translocation to mitochondria";"Transcription of E2F targets under negative control by DREAM complex";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Cyclin A:Cdk2-associated events at S phase entry";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcriptional Regulation by E2F6";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription" XP_037297750.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_037294325.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955 "RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation" XP_030031629.2 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_030040409.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_037300559.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037296899.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_030032106.2 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_030029231.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_030027875.1 1 Reactome: R-HSA-163765 "ChREBP activates metabolic gene expression" XP_030033022.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037293442.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection" XP_037302990.1 4 Reactome: R-HSA-176974;Reactome: R-HSA-69205;Reactome: R-HSA-176187;Reactome: R-HSA-68962 "Unwinding of DNA";"G1/S-Specific Transcription";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex" XP_030028106.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434 "MHC class II antigen presentation";"Kinesins";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic" XP_030033212.1 6 MetaCyc: PWY-6309;MetaCyc: PWY-7765;Reactome: R-HSA-71240;KEGG: 00380+1.14.13.9;MetaCyc: PWY-7717;MetaCyc: PWY-5651 "L-tryptophan degradation XI (mammalian, via kynurenine)";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan catabolism";"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde" XP_030035594.2 3 Reactome: R-HSA-6804757;Reactome: R-HSA-3899300;Reactome: R-HSA-9609690 "Regulation of TP53 Degradation";"SUMOylation of transcription cofactors";"HCMV Early Events" XP_037302595.1 7 KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;MetaCyc: PWY-6367;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052 "Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis" XP_037293240.1 9 MetaCyc: PWY-6703;MetaCyc: PWY-5664;MetaCyc: PWY-7852;MetaCyc: PWY-7442;MetaCyc: PWY-6147;MetaCyc: PWY-5663;Reactome: R-HSA-1474151;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6983 "Preq0 biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Drosopterin and aurodrosopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis";"Threo-tetrahydrobiopterin biosynthesis" XP_037300084.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_030033674.1 3 MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6 "Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism" XP_030026591.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_037303184.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_030032099.2 7 MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445 "Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation" XP_030024475.2 18 Reactome: R-HSA-1482925;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8051;Reactome: R-HSA-1482922;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;Reactome: R-HSA-1483166;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-8053;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4 "Acyl chain remodelling of PG";"Plasmalogen degradation";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Acyl chain remodelling of PI";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Synthesis of PA";"Linoleic acid metabolism";"Acyl chain remodelling of PS";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism" XP_030028402.1 13 Reactome: R-HSA-186797;Reactome: R-HSA-3000178;Reactome: R-HSA-216083;Reactome: R-HSA-1650814;Reactome: R-HSA-1474244;Reactome: R-HSA-8948216;Reactome: R-HSA-3000157;Reactome: R-HSA-2214320;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-419037;Reactome: R-HSA-2243919;Reactome: R-HSA-3000171 "Signaling by PDGF";"ECM proteoglycans";"Integrin cell surface interactions";"Collagen biosynthesis and modifying enzymes";"Extracellular matrix organization";"Collagen chain trimerization";"Laminin interactions";"Anchoring fibril formation";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"NCAM1 interactions";"Crosslinking of collagen fibrils";"Non-integrin membrane-ECM interactions" XP_030040542.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037297368.1 2 Reactome: R-HSA-3000178;MetaCyc: PWY-7511 "ECM proteoglycans";"Protein ubiquitination" XP_030021203.2 4 Reactome: R-HSA-446199;Reactome: R-HSA-4755609;KEGG: 00900+2.5.1.87;MetaCyc: PWY-6129 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59";"Terpenoid backbone biosynthesis";"Dolichol and dolichyl phosphate biosynthesis" XP_030028100.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037298044.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037302976.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72695 "Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex" XP_037293734.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_037298566.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_037300276.1 5 MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922 "Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_037301236.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_030029058.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037297790.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_030036004.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_030023578.2 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_030020000.1 13 MetaCyc: PWY-6842;MetaCyc: PWY-6370;MetaCyc: PWY-7112;KEGG: 00982+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-2261;Reactome: R-HSA-156590;KEGG: 00980+2.5.1.18;Reactome: R-HSA-196836;KEGG: 00053+1.8.5.1;KEGG: 00983+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-7533 "Glutathione-mediated detoxification II";"Ascorbate recycling (cytosolic)";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - cytochrome P450";"Glutathione metabolism";"Ascorbate glutathione cycle";"Glutathione conjugation";"Metabolism of xenobiotics by cytochrome P450";"Vitamin C (ascorbate) metabolism";"Ascorbate and aldarate metabolism";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis" XP_037298224.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_030031645.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_030027951.1 3 Reactome: R-HSA-913709;KEGG: 00510+2.4.1.117;Reactome: R-HSA-480985 "O-linked glycosylation of mucins";"N-Glycan biosynthesis";"Synthesis of dolichyl-phosphate-glucose" XP_030021135.1 8 KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Signaling by Hippo";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway" XP_037295983.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037302868.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_030024447.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_030031731.1 9 Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-5696394;Reactome: R-HSA-6782135;Reactome: R-HSA-8951664;Reactome: R-HSA-6782210;Reactome: R-HSA-110314 "Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"DNA Damage Recognition in GG-NER";"Dual incision in TC-NER";"Neddylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex" XP_030040936.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_037293809.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037302871.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_030033276.2 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_030022265.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037300751.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_037303415.1 3 Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037296282.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_030030659.1 2 Reactome: R-HSA-1369007;Reactome: R-HSA-5683371 "Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)" XP_037297712.1 4 Reactome: R-HSA-186763;Reactome: R-HSA-373753;Reactome: R-HSA-4420097;Reactome: R-HSA-428540 "Downstream signal transduction";"Nephrin family interactions";"VEGFA-VEGFR2 Pathway";"Activation of RAC1" XP_030037832.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_037299130.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7725 "Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_030035118.2 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037299570.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_030025816.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_030027620.2 3 KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1 "Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis" XP_030032331.2 1 Reactome: R-HSA-72731 "Recycling of eIF2:GDP" XP_037298378.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037299964.1 11 KEGG: 00910+6.3.1.2;KEGG: 00220+6.3.1.2;Reactome: R-HSA-210455;MetaCyc: PWY-6549;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6964;Reactome: R-HSA-8964539;MetaCyc: PWY-381;MetaCyc: PWY-5675;MetaCyc: PWY-6963;KEGG: 00630+6.3.1.2 "Nitrogen metabolism";"Arginine biosynthesis";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"L-glutamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle II";"Glutamate and glutamine metabolism";"Nitrate reduction II (assimilatory)";"Nitrate reduction V (assimilatory)";"Ammonia assimilation cycle I";"Glyoxylate and dicarboxylate metabolism" XP_030021524.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-8041;Reactome: R-HSA-75876 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs" XP_037296640.1 10 Reactome: R-HSA-382556;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-9648895;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-381042;Reactome: R-HSA-72695;Reactome: R-HSA-72731;Reactome: R-HSA-156827 "ABC-family proteins mediated transport";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK1 (HRI) to heme deficiency";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"PERK regulates gene expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Recycling of eIF2:GDP";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_037302225.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_030033747.1 3 Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597 "Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"G alpha (z) signalling events" XP_030035441.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68962 "Switching of origins to a post-replicative state";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex" XP_037293445.1 7 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway" XP_030032635.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_030036545.1 5 Reactome: R-HSA-9633012;Reactome: R-HSA-380994;KEGG: 00250+6.3.5.4;Reactome: R-HSA-8963693;Reactome: R-HSA-9648895 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"Response of EIF2AK1 (HRI) to heme deficiency" XP_030037508.2 15 Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-176412;Reactome: R-HSA-141430 "Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex" XP_037294003.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037296960.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_030032209.2 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_030030247.2 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_037295618.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_030032295.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-191859 "RNA polymerase II transcribes snRNA genes";"snRNP Assembly"